|
|
negative regulation of glomerulus development
|
GO:0090194 |
2 |
0.991
|
|
|
|
negative regulation of kidney development
|
GO:0090185 |
2 |
0.975
|
|
|
|
pattern specification involved in kidney development
|
GO:0061004 |
1 |
0.956
|
|
|
|
negative regulation of cell proliferation involved in kidney development
|
GO:1901723 |
2 |
0.955
|
|
|
|
negative regulation of glucocorticoid biosynthetic process
|
GO:0031947 |
4 |
0.946
|
|
|
|
negative regulation of steroid hormone biosynthetic process
|
GO:0090032 |
4 |
0.919
|
|
|
|
renal system pattern specification
|
GO:0072048 |
1 |
0.904
|
|
|
|
positive regulation of aldosterone metabolic process
|
GO:0032346 |
2 |
0.886
|
|
|
|
regulation of glomerulus development
|
GO:0090192 |
3 |
0.829
|
Mouse |
|
|
mesendoderm development
|
GO:0048382 |
1 |
0.814
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.812
|
Mouse |
|
|
negative regulation of cell fate specification
|
GO:0009996 |
3 |
0.786
|
Zebrafish |
|
|
regulation of cell proliferation involved in kidney development
|
GO:1901722 |
3 |
0.750
|
|
|
|
negative regulation of endodermal cell differentiation
|
GO:1903225 |
2 |
0.733
|
Zebrafish |
|
|
regulation of aldosterone biosynthetic process
|
GO:0032347 |
6 |
0.728
|
|
|
|
negative regulation of gastrulation
|
GO:2000542 |
4 |
0.705
|
Zebrafish |
|
|
negative regulation of glomerular mesangial cell proliferation
|
GO:0072125 |
2 |
0.680
|
|
|
|
positive regulation of aldosterone biosynthetic process
|
GO:0032349 |
2 |
0.671
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.602
|
Zebrafish |
|
|
regulation of endodermal cell fate specification
|
GO:0042663 |
1 |
0.589
|
Zebrafish |
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.586
|
Zebrafish |
|
|
cortisol biosynthetic process
|
GO:0034651 |
8 |
0.574
|
|
|
|
positive regulation of pathway restricted smad protein phosphorylation
|
GO:0010862 |
22 |
0.573
|
|
|
|
regulation of glomerular mesangial cell proliferation
|
GO:0072124 |
3 |
0.482
|
|
|
|
positive regulation of odontogenesis
|
GO:0042482 |
3 |
0.471
|
|
|
|
hyaluranon cable assembly
|
GO:0036118 |
3 |
0.465
|
|
|
|
bmp signaling pathway involved in heart development
|
GO:0061312 |
3 |
0.454
|
|
|
|
aldosterone biosynthetic process
|
GO:0032342 |
9 |
0.416
|
|
|
|
positive regulation of hormone biosynthetic process
|
GO:0046886 |
4 |
0.404
|
|
|
|
mineralocorticoid metabolic process
|
GO:0008212 |
9 |
0.397
|
|
|
|
cell proliferation involved in kidney development
|
GO:0072111 |
3 |
0.394
|
|
|
|
mesenchymal to epithelial transition involved in metanephros morphogenesis
|
GO:0003337 |
4 |
0.385
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.376
|
|
|
|
positive regulation of steroid hormone biosynthetic process
|
GO:0090031 |
2 |
0.374
|
|
|
|
enteroendocrine cell differentiation
|
GO:0035883 |
6 |
0.374
|
|
|
|
prostate gland morphogenesis
|
GO:0060512 |
1 |
0.338
|
Mouse |
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.332
|
|
|
|
kidney morphogenesis
|
GO:0060993 |
19 |
0.331
|
Mouse |
|
|
mesonephros development
|
GO:0001823 |
17 |
0.311
|
Mouse |
|
|
regulation of organ formation
|
GO:0003156 |
4 |
0.309
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.295
|
|
|
|
ureteric bud development
|
GO:0001657 |
13 |
0.278
|
Mouse |
|
|
type b pancreatic cell development
|
GO:0003323 |
4 |
0.278
|
|
|
|
negative regulation of mesenchymal cell proliferation
|
GO:0072201 |
3 |
0.277
|
|
|
|
negative regulation of glucocorticoid metabolic process
|
GO:0031944 |
4 |
0.268
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.262
|
Mouse |
|
|
regulation of cortisol biosynthetic process
|
GO:2000064 |
5 |
0.260
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.253
|
|
|
|
regulation of ketone biosynthetic process
|
GO:0010566 |
7 |
0.248
|
|
|
|
positive regulation of biomineral tissue development
|
GO:0070169 |
20 |
0.245
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.244
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.238
|
|
|
|
kidney epithelium development
|
GO:0072073 |
25 |
0.237
|
Mouse |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.236
|
|
|
|
glomerular mesangial cell proliferation
|
GO:0072110 |
3 |
0.236
|
|
|
|
bone mineralization
|
GO:0030282 |
34 |
0.232
|
|
|
|
forebrain regionalization
|
GO:0021871 |
3 |
0.226
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.225
|
|
|
|
glandular epithelial cell development
|
GO:0002068 |
5 |
0.222
|
|
|
|
nephron morphogenesis
|
GO:0072028 |
15 |
0.218
|
Mouse |
|
|
positive regulation of hyaluranon cable assembly
|
GO:1900106 |
3 |
0.215
|
|
|
|
ketone biosynthetic process
|
GO:0042181 |
17 |
0.212
|
|
|
|
mesonephric epithelium development
|
GO:0072163 |
14 |
0.207
|
Mouse |
|
|
endocrine pancreas development
|
GO:0031018 |
11 |
0.206
|
|
|
|
negative regulation of trophoblast cell migration
|
GO:1901164 |
3 |
0.206
|
|
|
|
branching involved in salivary gland morphogenesis
|
GO:0060445 |
1 |
0.202
|
|
|
|
regulation of activin receptor signaling pathway
|
GO:0032925 |
14 |
0.199
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.196
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.196
|
|
|
|
regulation of insulin like growth factor receptor signaling pathway
|
GO:0043567 |
8 |
0.195
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.195
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.194
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.186
|
|
|
|
mineralocorticoid biosynthetic process
|
GO:0006705 |
9 |
0.185
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.183
|
|
|
|
monocyte aggregation
|
GO:0070487 |
4 |
0.183
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.182
|
|
|
|
endodermal mesodermal cell signaling
|
GO:0003133 |
3 |
0.181
|
|
|
|
alcohol metabolic process
|
GO:0006066 |
114 |
0.177
|
|
|
|
embryonic skeletal joint morphogenesis
|
GO:0060272 |
2 |
0.177
|
|
|
|
cell fate commitment involved in formation of primary germ layer
|
GO:0060795 |
6 |
0.176
|
Zebrafish |
|
|
cellular hormone metabolic process
|
GO:0034754 |
41 |
0.175
|
|
|
|
hormone metabolic process
|
GO:0042445 |
61 |
0.174
|
|
|
|
negative regulation of insulin like growth factor receptor signaling pathway
|
GO:0043569 |
4 |
0.171
|
|
|
|
specification of organ identity
|
GO:0010092 |
3 |
0.170
|
|
|
|
mesonephric tubule development
|
GO:0072164 |
14 |
0.169
|
Mouse |
|
|
embryonic skeletal joint development
|
GO:0072498 |
2 |
0.169
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.168
|
|
|
|
regulation of muscle cell differentiation
|
GO:0051147 |
31 |
0.164
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.163
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.162
|
|
|
|
regulation of aldosterone metabolic process
|
GO:0032344 |
6 |
0.160
|
|
|
|
regulation of branching involved in ureteric bud morphogenesis
|
GO:0090189 |
3 |
0.159
|
Mouse |
|
|
positive regulation of ossification
|
GO:0045778 |
32 |
0.154
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.153
|
|
|
|
epithelial tube branching involved in lung morphogenesis
|
GO:0060441 |
4 |
0.150
|
|
|
|
embryonic camera type eye morphogenesis
|
GO:0048596 |
2 |
0.149
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.149
|
|
|
|
dna dependent dna replication
|
GO:0006261 |
44 |
0.140
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.138
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.134
|
Mouse |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.133
|
|
|
|
determination of dorsal ventral asymmetry
|
GO:0048262 |
4 |
0.133
|
|
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.133
|
|
|
|
positive regulation of alcohol biosynthetic process
|
GO:1902932 |
9 |
0.132
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.132
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.130
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.130
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
0.129
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.128
|
|
|
|
positive regulation of bone mineralization
|
GO:0030501 |
19 |
0.126
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.124
|
|
|
|
negative regulation of embryonic development
|
GO:0045992 |
4 |
0.124
|
Zebrafish |
|
|
activin receptor signaling pathway
|
GO:0032924 |
24 |
0.123
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
19 |
0.123
|
Mouse |
|
|
negative regulation of cortisol biosynthetic process
|
GO:2000065 |
4 |
0.122
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.122
|
|
|
|
c21 steroid hormone biosynthetic process
|
GO:0006700 |
11 |
0.121
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.121
|
|
|
|
glomerulus development
|
GO:0032835 |
15 |
0.120
|
Mouse |
|
|
endoderm formation
|
GO:0001706 |
33 |
0.119
|
Zebrafish Mouse |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.119
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.119
|
|
|
|
branch elongation involved in ureteric bud branching
|
GO:0060681 |
2 |
0.118
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.118
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.118
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.117
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.116
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.115
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.114
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.114
|
Zebrafish Mouse |
|
|
regulation of hormone biosynthetic process
|
GO:0046885 |
10 |
0.114
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
25 |
0.114
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.113
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.113
|
Mouse |
|
|
calcium independent cell cell adhesion via plasma membrane cell adhesion molecules
|
GO:0016338 |
2 |
0.113
|
|
|
|
lung alveolus development
|
GO:0048286 |
4 |
0.113
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.113
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.113
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.113
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.113
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.112
|
Mouse |
|
|
neuroendocrine cell differentiation
|
GO:0061101 |
2 |
0.112
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.111
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.111
|
|
|
|
ureteric bud elongation
|
GO:0060677 |
2 |
0.110
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.110
|
|
|
|
negative regulation of hormone metabolic process
|
GO:0032351 |
6 |
0.110
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.110
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.109
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.109
|
|
|
|
negative regulation of chorionic trophoblast cell proliferation
|
GO:1901383 |
2 |
0.108
|
|
|
|
regulation of steroid biosynthetic process
|
GO:0050810 |
23 |
0.107
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.106
|
|
|
|
regulation of bone mineralization
|
GO:0030500 |
29 |
0.106
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.105
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.105
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.104
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.104
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.101
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.101
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.100
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.100
|
|
|
|
regulation of smad protein import into nucleus
|
GO:0060390 |
10 |
0.100
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.099
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.097
|
Mouse |
|
|
steroid biosynthetic process
|
GO:0006694 |
46 |
0.097
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.097
|
|
|
|
endodermal cell differentiation
|
GO:0035987 |
31 |
0.096
|
Zebrafish |
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.096
|
|
|
|
heart formation
|
GO:0060914 |
2 |
0.096
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.095
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.094
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.094
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.094
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.093
|
|
|
|
ureter development
|
GO:0072189 |
3 |
0.093
|
|
|
|
metanephros development
|
GO:0001656 |
16 |
0.092
|
|
|
|
negative regulation of cardiac muscle cell differentiation
|
GO:2000726 |
3 |
0.092
|
|
|
|
patterning of blood vessels
|
GO:0001569 |
2 |
0.092
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.092
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.092
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.091
|
|
|
|
positive regulation of p38mapk cascade
|
GO:1900745 |
8 |
0.091
|
|
|
|
mesodermal cell fate commitment
|
GO:0001710 |
2 |
0.091
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.090
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.090
|
|
|
|
positive regulation of multicellular organismal metabolic process
|
GO:0044253 |
11 |
0.090
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.090
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.090
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.088
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.088
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.088
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.087
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.087
|
|
|
|
regulation of hormone metabolic process
|
GO:0032350 |
14 |
0.087
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.086
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.086
|
Zebrafish Mouse |
|
|
negative regulation of aldosterone biosynthetic process
|
GO:0032348 |
4 |
0.086
|
|
|
|
prostate gland development
|
GO:0030850 |
3 |
0.086
|
Mouse |
|
|
aldosterone metabolic process
|
GO:0032341 |
9 |
0.086
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.086
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.085
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.085
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.085
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.084
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.084
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.084
|
Mouse |
|
|
immune response
|
GO:0006955 |
307 |
0.084
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.083
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.083
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.083
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.082
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.082
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.082
|
Mouse |
|
|
organic hydroxy compound biosynthetic process
|
GO:1901617 |
71 |
0.082
|
|
|
|
positive regulation of sarcomere organization
|
GO:0060298 |
2 |
0.082
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.082
|
|
|
|
positive regulation of gliogenesis
|
GO:0014015 |
4 |
0.081
|
|
|
|
chorionic trophoblast cell proliferation
|
GO:0097360 |
2 |
0.081
|
|
|
|
type b pancreatic cell differentiation
|
GO:0003309 |
5 |
0.081
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.081
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.081
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.080
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.080
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.080
|
|
|
|
positive regulation of striated muscle cell differentiation
|
GO:0051155 |
9 |
0.080
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.080
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.080
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.080
|
Mouse |
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.079
|
|
|
|
glucocorticoid metabolic process
|
GO:0008211 |
10 |
0.079
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.079
|
Mouse |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.079
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.078
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.078
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.078
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.078
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.078
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.078
|
Mouse |
|
|
regulation of gastrulation
|
GO:0010470 |
12 |
0.077
|
Zebrafish |
|
|
ossification
|
GO:0001503 |
121 |
0.077
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.076
|
|
|
|
cortisol metabolic process
|
GO:0034650 |
8 |
0.076
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.076
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.076
|
|
|
|
regulation of odontogenesis
|
GO:0042481 |
4 |
0.075
|
|
|
|
regulation of biomineral tissue development
|
GO:0070167 |
31 |
0.075
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.075
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.075
|
|
|
|
striated muscle cell apoptotic process
|
GO:0010658 |
3 |
0.075
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.075
|
|
|
|
multicellular organismal metabolic process
|
GO:0044236 |
34 |
0.074
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.074
|
|
|
|
nephric duct development
|
GO:0072176 |
4 |
0.073
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.073
|
|
|
|
pericardium development
|
GO:0060039 |
2 |
0.073
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.073
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.072
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.072
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.071
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.071
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.071
|
|
|
|
apoptotic process involved in morphogenesis
|
GO:0060561 |
3 |
0.071
|
|
|
|
glucocorticoid biosynthetic process
|
GO:0006704 |
8 |
0.071
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.071
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.070
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.070
|
|
|
|
negative regulation of cell fate commitment
|
GO:0010454 |
3 |
0.070
|
Zebrafish |
|
|
morphogenesis of a branching structure
|
GO:0001763 |
21 |
0.070
|
Mouse |
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.070
|
|
|
|
negative regulation of striated muscle cell apoptotic process
|
GO:0010664 |
2 |
0.070
|
|
|
|
regulation of hyaluranon cable assembly
|
GO:1900104 |
3 |
0.070
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.070
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.070
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.069
|
Zebrafish Mouse |
|
|
regulation of chorionic trophoblast cell proliferation
|
GO:1901382 |
2 |
0.069
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.069
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.068
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.068
|
|
|
|
smad protein signal transduction
|
GO:0060395 |
10 |
0.068
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.068
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.067
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.067
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.067
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.067
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.067
|
|
|
|
nephron development
|
GO:0072006 |
30 |
0.067
|
Mouse |
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.066
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.066
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.066
|
|
|
|
system process
|
GO:0003008 |
349 |
0.065
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.065
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.065
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.065
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.065
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.065
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.064
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.064
|
Mouse |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.064
|
Mouse |
|
|
steroid metabolic process
|
GO:0008202 |
94 |
0.064
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.064
|
Mouse |
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.064
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.063
|
|
|
|
kidney vasculature development
|
GO:0061440 |
7 |
0.063
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.063
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.063
|
Mouse |
|
|
embryonic eye morphogenesis
|
GO:0048048 |
2 |
0.062
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.062
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.062
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.062
|
|
|
|
regulation of endodermal cell differentiation
|
GO:1903224 |
3 |
0.062
|
Zebrafish |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.062
|
Zebrafish Mouse |
|
|
axis elongation
|
GO:0003401 |
4 |
0.061
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.061
|
|
|
|
positive regulation of muscle organ development
|
GO:0048636 |
7 |
0.061
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.061
|
Mouse |
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.061
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.061
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.061
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.060
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.060
|
Mouse |
|
|
positive regulation of muscle cell differentiation
|
GO:0051149 |
15 |
0.060
|
|
|
|
endoderm development
|
GO:0007492 |
33 |
0.060
|
Zebrafish Mouse |
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.060
|
|
|
|
pancreas development
|
GO:0031016 |
19 |
0.059
|
|
|
|
energy homeostasis
|
GO:0097009 |
3 |
0.059
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.059
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.059
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.059
|
|
|
|
regulation of mesonephros development
|
GO:0061217 |
3 |
0.059
|
Mouse |
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.059
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.058
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.058
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.057
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.057
|
|
|
|
odontogenesis
|
GO:0042476 |
25 |
0.057
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.057
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.057
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.057
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.057
|
Mouse |
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.056
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.056
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.056
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.056
|
|
|
|
c21 steroid hormone metabolic process
|
GO:0008207 |
17 |
0.056
|
|
|
|
negative regulation of vasculature development
|
GO:1901343 |
43 |
0.056
|
|
|
|
nephric duct formation
|
GO:0072179 |
1 |
0.056
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.056
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.055
|
|
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.055
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.055
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.055
|
|
|
|
biomineral tissue development
|
GO:0031214 |
39 |
0.055
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.054
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.054
|
Mouse |
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.054
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.054
|
|
|
|
positive regulation of endothelial cell proliferation
|
GO:0001938 |
37 |
0.054
|
|
|
|
regulation of apoptotic process involved in morphogenesis
|
GO:1902337 |
1 |
0.054
|
|
|
|
positive regulation of dna replication
|
GO:0045740 |
35 |
0.054
|
|
|
|
glandular epithelial cell differentiation
|
GO:0002067 |
6 |
0.053
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.053
|
|
|
|
thymocyte apoptotic process
|
GO:0070242 |
2 |
0.053
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.053
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.053
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.053
|
|
|
|
bmp signaling pathway involved in heart induction
|
GO:0003130 |
3 |
0.053
|
|
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.051
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.051
|
Mouse |
|
|
gastrulation
|
GO:0007369 |
51 |
0.051
|
Zebrafish Mouse |
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.051
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.051
|
|
|
|
endodermal mesodermal cell signaling involved in heart induction
|
GO:0003134 |
3 |
0.051
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.050
|
|
|
|
growth
|
GO:0040007 |
202 |
0.050
|
Mouse |
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.050
|
Mouse |
|
|
oocyte development
|
GO:0048599 |
1 |
0.050
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.050
|
|
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
4 |
0.049
|
|
|
|
regulation of wnt signaling pathway involved in heart development
|
GO:0003307 |
3 |
0.049
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.049
|
|
|
|
alcohol biosynthetic process
|
GO:0046165 |
52 |
0.049
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.049
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.049
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.049
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.049
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.049
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.049
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.048
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.048
|
|
|
|
regulation of sarcomere organization
|
GO:0060297 |
3 |
0.048
|
|
|
|
regulation of cellular response to oxidative stress
|
GO:1900407 |
26 |
0.048
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.048
|
|
|
|
negative regulation of mesonephros development
|
GO:0061218 |
1 |
0.048
|
|
|
|
regulation of alcohol biosynthetic process
|
GO:1902930 |
22 |
0.047
|
|
|
|
secondary heart field specification
|
GO:0003139 |
2 |
0.047
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.046
|
Zebrafish Mouse |
|
|
regulation of dna replication
|
GO:0006275 |
68 |
0.046
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.046
|
|
|
|
regulation of cardiac muscle contraction
|
GO:0055117 |
33 |
0.046
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.046
|
|
|
|
response to dietary excess
|
GO:0002021 |
2 |
0.046
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.045
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.045
|
Mouse |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.045
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.045
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.045
|
|
|
|
glomerulus vasculature development
|
GO:0072012 |
6 |
0.045
|
|
|
|
hormone mediated signaling pathway
|
GO:0009755 |
22 |
0.045
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.045
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.045
|
Zebrafish Mouse |
|
|
heart field specification
|
GO:0003128 |
2 |
0.045
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.044
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.044
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.044
|
|
|
|
regulation of muscle organ development
|
GO:0048634 |
27 |
0.044
|
Mouse |
|
|
regulation of astrocyte differentiation
|
GO:0048710 |
3 |
0.044
|
Mouse |
|
|
heart development
|
GO:0007507 |
95 |
0.044
|
Mouse |
|
|
regulation of pathway restricted smad protein phosphorylation
|
GO:0060393 |
34 |
0.043
|
|
|
|
atrioventricular valve development
|
GO:0003171 |
3 |
0.043
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.043
|
Mouse |
|
|
regulation of cell fate commitment
|
GO:0010453 |
7 |
0.043
|
Zebrafish |
|
|
regulation of growth
|
GO:0040008 |
165 |
0.043
|
Mouse |
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.043
|
|
|
|
organ induction
|
GO:0001759 |
4 |
0.042
|
|
|
|
endocardial cushion development
|
GO:0003197 |
3 |
0.042
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.042
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus
|
GO:1901522 |
2 |
0.042
|
|
|
|
positive regulation of smad protein import into nucleus
|
GO:0060391 |
8 |
0.042
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.042
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.041
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.041
|
Zebrafish Mouse |
|
|
positive regulation of cardiac muscle cell differentiation
|
GO:2000727 |
4 |
0.041
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.041
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.041
|
|
|
|
dna biosynthetic process
|
GO:0071897 |
40 |
0.041
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.041
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.041
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.041
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.040
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.040
|
|
|
|
regulation of glial cell differentiation
|
GO:0045685 |
3 |
0.040
|
Mouse |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.040
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.040
|
|
|
|
regulation of stem cell maintenance
|
GO:2000036 |
4 |
0.039
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.039
|
|
|
|
negative regulation of steroid biosynthetic process
|
GO:0010894 |
15 |
0.039
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.039
|
|
|
|
s shaped body morphogenesis
|
GO:0072050 |
4 |
0.039
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.039
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.039
|
Mouse |
|
|
epithelial cell proliferation involved in lung morphogenesis
|
GO:0060502 |
3 |
0.039
|
|
|
|
astrocyte differentiation
|
GO:0048708 |
4 |
0.039
|
Mouse |
|
|
steroid hormone mediated signaling pathway
|
GO:0043401 |
12 |
0.039
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.039
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.038
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.038
|
Mouse |
|
|
pituitary gland development
|
GO:0021983 |
2 |
0.038
|
Mouse |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.038
|
|
|
|
renal vesicle development
|
GO:0072087 |
4 |
0.038
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.038
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.038
|
|
|
|
negative regulation of epidermal cell differentiation
|
GO:0045605 |
4 |
0.037
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.037
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.037
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.037
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.037
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.037
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.037
|
|
|
|
peptide secretion
|
GO:0002790 |
51 |
0.036
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.036
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.036
|
|
|
|
negative regulation of aldosterone metabolic process
|
GO:0032345 |
4 |
0.036
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.036
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.036
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.036
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.036
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.036
|
|
|
|
regulation of energy homeostasis
|
GO:2000505 |
1 |
0.035
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.035
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.035
|
Mouse |
|
|
smad protein import into nucleus
|
GO:0007184 |
13 |
0.035
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.035
|
|
|
|
positive regulation of muscle hypertrophy
|
GO:0014742 |
6 |
0.034
|
|
