IMP

Process View

Homo sapiens

14 genes annotated in human

mesonephric tubule development

The progression of a mesonephric tubule over time, from its initial formation to the mature structure. A mesonephric tubule is an epithelial tube that is part of the mesonephros.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "mesonephric tubule development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "mesonephric tubule development" (in gray)

Name	Description	Probability	Func Analog Organism
FGFR2	fibroblast growth factor receptor 2	1.000	Mouse
SMAD3	SMAD family member 3	1.000	Mouse
SMAD2	SMAD family member 2	0.973	Mouse
FGF1	fibroblast growth factor 1 (acidic)	0.973
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.959
SMAD1	SMAD family member 1	0.939	Mouse
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.894
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.708
SMAD7	SMAD family member 7	0.570	Mouse
RXRA	retinoid X receptor, alpha	0.473
MEIS1	Meis homeobox 1	0.432
FGF10	fibroblast growth factor 10	0.363	Human
MEIS2	Meis homeobox 2	0.355
EGR2	early growth response 2	0.348	Human
SMAD9	SMAD family member 9	0.319	Mouse
NKX2-1	NK2 homeobox 1	0.316
PLCG1	phospholipase C, gamma 1	0.293
PKD2	polycystic kidney disease 2 (autosomal dominant)	0.232
PKD1	polycystic kidney disease 1 (autosomal dominant)	0.231
FGF8	fibroblast growth factor 8 (androgen-induced)	0.210
HOXA10	homeobox A10	0.204
BMP7	bone morphogenetic protein 7	0.198	Mouse
FSTL1	follistatin-like 1	0.190
SKIL	SKI-like oncogene	0.185
MSN	moesin	0.174
NOG	noggin	0.169	Mouse
CCNE1	cyclin E1	0.164
MEOX1	mesenchyme homeobox 1	0.152
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.147
TRPV5	transient receptor potential cation channel, subfamily V, member 5	0.124
COL2A1	collagen, type II, alpha 1	0.113
FGF18	fibroblast growth factor 18	0.111
MAGED2	melanoma antigen family D, 2	0.111
SMAD6	SMAD family member 6	0.105	Mouse
ADAM17	ADAM metallopeptidase domain 17	0.092
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.091
TIMP3	TIMP metallopeptidase inhibitor 3	0.088
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.084
PJA1	praja ring finger 1	0.084
MED25	mediator complex subunit 25	0.084
PARVA	parvin, alpha	0.080
HOXB5	homeobox B5	0.080
FGFR3	fibroblast growth factor receptor 3	0.073
WNT1	wingless-type MMTV integration site family, member 1	0.071	Human Mouse
BCAM	basal cell adhesion molecule (Lutheran blood group)	0.067
CPE	carboxypeptidase E	0.062
NCOA1	nuclear receptor coactivator 1	0.059
PAX8	paired box 8	0.059
CXXC5	CXXC finger protein 5	0.058
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.058
NOTCH1	notch 1	0.057
FGF7	fibroblast growth factor 7	0.057	Human
TGFBR1	transforming growth factor, beta receptor 1	0.057
RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.055
ENG	endoglin	0.054
CREBBP	CREB binding protein	0.053
LBX1	ladybird homeobox 1	0.052
EGR1	early growth response 1	0.050	Human
FGF3	fibroblast growth factor 3	0.050	Human
BMP2	bone morphogenetic protein 2	0.048	Human Mouse
FGFR1	fibroblast growth factor receptor 1	0.046	Mouse
EGR3	early growth response 3	0.044	Human
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.044
TRPC1	transient receptor potential cation channel, subfamily C, member 1	0.039
PAX2	paired box 2	0.039
INHBB	inhibin, beta B	0.038
BMP4	bone morphogenetic protein 4	0.038
SMAD4	SMAD family member 4	0.036	Mouse
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.035
FOXF2	forkhead box F2	0.035
SPRY2	sprouty homolog 2 (Drosophila)	0.034
FBLN1	fibulin 1	0.033
FZD7	frizzled homolog 7 (Drosophila)	0.033
LAPTM5	lysosomal protein transmembrane 5	0.033
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.033
PRKD2	protein kinase D2	0.033
HOXC8	homeobox C8	0.030
FOXF1	forkhead box F1	0.030
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.029
FGF4	fibroblast growth factor 4	0.029	Human
HOXB6	homeobox B6	0.028
PAPPA	pregnancy-associated plasma protein A, pappalysin 1	0.028
PBK	PDZ binding kinase	0.027
AXIN1	axin 1	0.027
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.026
TGFB2	transforming growth factor, beta 2	0.026
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.025
HMGA2	high mobility group AT-hook 2	0.025
SFRP1	secreted frizzled-related protein 1	0.025	Mouse
FGF2	fibroblast growth factor 2 (basic)	0.024
FOXA2	forkhead box A2	0.024
SIM2	single-minded homolog 2 (Drosophila)	0.023
NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)	0.023
ADAMTS5	ADAM metallopeptidase with thrombospondin type 1 motif, 5	0.023
SIX2	SIX homeobox 2	0.023	Mouse
HOXA11	homeobox A11	0.022	Mouse
JAG2	jagged 2	0.022
SPRY4	sprouty homolog 4 (Drosophila)	0.021
NCOA6	nuclear receptor coactivator 6	0.021
WT1	Wilms tumor 1	0.020
WNT4	wingless-type MMTV integration site family, member 4	0.020	Human
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.020
THBS1	thrombospondin 1	0.020
SLIT2	slit homolog 2 (Drosophila)	0.020
HOXD13	homeobox D13	0.019
RUNX1	runt-related transcription factor 1	0.019
SMAD5	SMAD family member 5	0.019	Mouse
AR	androgen receptor	0.019
FOXC1	forkhead box C1	0.019	Mouse
TBX2	T-box 2	0.019
HNF1A	HNF1 homeobox A	0.018
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.018
GAS1	growth arrest-specific 1	0.018
FST	follistatin	0.018
COL13A1	collagen, type XIII, alpha 1	0.018
WNT11	wingless-type MMTV integration site family, member 11	0.018
BBS1	Bardet-Biedl syndrome 1	0.018
EZR	ezrin	0.018
EYA2	eyes absent homolog 2 (Drosophila)	0.018
WNT3	wingless-type MMTV integration site family, member 3	0.018	Human
FZD8	frizzled homolog 8 (Drosophila)	0.017
HMGA1	high mobility group AT-hook 1	0.017
MDFI	MyoD family inhibitor	0.017
CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)	0.017
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.016
WIF1	WNT inhibitory factor 1	0.016
SOX1	SRY (sex determining region Y)-box 1	0.016
GDNF	glial cell derived neurotrophic factor	0.016
SOX9	SRY (sex determining region Y)-box 9	0.016	Mouse
SOX2	SRY (sex determining region Y)-box 2	0.016
NPHP1	nephronophthisis 1 (juvenile)	0.016
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.016
SFRP4	secreted frizzled-related protein 4	0.016
TAOK1	TAO kinase 1	0.015
DIP2A	DIP2 disco-interacting protein 2 homolog A (Drosophila)	0.015
MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.015
CADM4	cell adhesion molecule 4	0.015
ZNF205	zinc finger protein 205	0.015
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.015
CSF2	colony stimulating factor 2 (granulocyte-macrophage)	0.015
FOXL1	forkhead box L1	0.015
AQP5	aquaporin 5	0.015
GLI3	GLI family zinc finger 3	0.014	Mouse
CSNK1E	casein kinase 1, epsilon	0.014
RAX	retina and anterior neural fold homeobox	0.014
TBX5	T-box 5	0.014
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.014
HOXB9	homeobox B9	0.014
CAPN6	calpain 6	0.014
MYH10	myosin, heavy chain 10, non-muscle	0.014
FZD10	frizzled homolog 10 (Drosophila)	0.014
THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)	0.014
HOXD10	homeobox D10	0.014
COL7A1	collagen, type VII, alpha 1	0.014
CLDN4	claudin 4	0.014
TCF4	transcription factor 4	0.013
SIX6	SIX homeobox 6	0.013
DLX4	distal-less homeobox 4	0.013
DUSP6	dual specificity phosphatase 6	0.013
SNAI1	snail homolog 1 (Drosophila)	0.013
GFRA1	GDNF family receptor alpha 1	0.013
FRS2	fibroblast growth factor receptor substrate 2	0.013
GATA2	GATA binding protein 2	0.013
CRHR1	corticotropin releasing hormone receptor 1	0.013
CALCA	calcitonin-related polypeptide alpha	0.013
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.012
MSX1	msh homeobox 1	0.012
C5orf13	chromosome 5 open reading frame 13	0.012
FGFR4	fibroblast growth factor receptor 4	0.012
PRRX2	paired related homeobox 2	0.012
ELN	elastin	0.012
IHH	Indian hedgehog	0.012
HES2	hairy and enhancer of split 2 (Drosophila)	0.012
HOXC5	homeobox C5	0.012
TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)	0.012
FOSB	FBJ murine osteosarcoma viral oncogene homolog B	0.012
STK36	serine/threonine kinase 36	0.012
EYA1	eyes absent homolog 1 (Drosophila)	0.012
RDH11	retinol dehydrogenase 11 (all-trans/9-cis/11-cis)	0.012
SEMA5A	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.011
ATF7IP	activating transcription factor 7 interacting protein	0.011
CLDN1	claudin 1	0.011
CHRD	chordin	0.011
THBS2	thrombospondin 2	0.011
GPC3	glypican 3	0.011
SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1	0.011
WNT7A	wingless-type MMTV integration site family, member 7A	0.011	Human
HIC1	hypermethylated in cancer 1	0.011
ZFYVE9	zinc finger, FYVE domain containing 9	0.011
JAG1	jagged 1	0.011
NEUROG2	neurogenin 2	0.011
NFIB	nuclear factor I/B	0.011
EVC2	Ellis van Creveld syndrome 2	0.011
MNX1	motor neuron and pancreas homeobox 1	0.010
CDC25B	cell division cycle 25 homolog B (S. pombe)	0.010
RBMS3	RNA binding motif, single stranded interacting protein 3	0.010
TCF21	transcription factor 21	0.010	Mouse
RSPO2	R-spondin 2 homolog (Xenopus laevis)	0.010
NKD2	naked cuticle homolog 2 (Drosophila)	0.010
PAX7	paired box 7	0.010
HOXB1	homeobox B1	0.010
NKX6-1	NK6 homeobox 1	0.010
LMO4	LIM domain only 4	0.010
FBLN2	fibulin 2	0.010
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.010
TBCD	tubulin folding cofactor D	0.010