Homo sapiens

261 known processes

PF4

platelet factor 4

(Aliases: SCYB4,CXCL4,MGC138298)

PF4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mhc class ii biosynthetic process GO:0045342 4 0.610
hemostasis GO:0007599 76 0.553
g protein coupled receptor signaling pathway GO:0007186 207 0.485
Human
blood coagulation GO:0007596 76 0.422
coagulation GO:0050817 78 0.405
regulation of camp metabolic process GO:0030814 52 0.389
leukocyte migration GO:0050900 107 0.379
regulation of mhc class ii biosynthetic process GO:0045346 4 0.377
regulation of body fluid levels GO:0050878 99 0.318
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 0.290
response to other organism GO:0051707 261 0.283
Human
cell adhesion GO:0007155 325 0.282
response to external biotic stimulus GO:0043207 261 0.279
Human
cell activation GO:0001775 213 0.274
hemopoiesis GO:0030097 180 0.273
blood vessel development GO:0001568 172 0.257
biological adhesion GO:0022610 331 0.254
response to bacterium GO:0009617 144 0.242
Human
response to biotic stimulus GO:0009607 276 0.238
Human
response to oxygen containing compound GO:1901700 369 0.228
Human
negative regulation of cell death GO:0060548 345 0.222
circulatory system development GO:0072359 262 0.220
cytokine production GO:0001816 247 0.213
platelet activation GO:0030168 44 0.206
sequestering of metal ion GO:0051238 24 0.197
negative regulation of apoptotic process GO:0043066 316 0.197
positive regulation of chemotaxis GO:0050921 57 0.196
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 20 0.196
regulation of response to external stimulus GO:0032101 222 0.190
negative regulation of developmental process GO:0051093 247 0.186
hematopoietic or lymphoid organ development GO:0048534 186 0.183
anatomical structure formation involved in morphogenesis GO:0048646 284 0.175
chemotaxis GO:0006935 157 0.175
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.175
cardiovascular system development GO:0072358 262 0.174
regulation of cell motility GO:2000145 299 0.170
Human
myeloid cell differentiation GO:0030099 117 0.167
digestive system development GO:0055123 75 0.167
regulation of locomotion GO:0040012 329 0.167
Human
response to cytokine GO:0034097 232 0.163
response to lipid GO:0033993 206 0.163
Human
regulation of behavior GO:0050795 82 0.161
positive regulation of cell motility GO:2000147 177 0.161
Human
regulation of cellular component movement GO:0051270 334 0.161
Human
granulocyte migration GO:0097530 40 0.160
apoptotic signaling pathway GO:0097190 268 0.158
regulation of cell migration GO:0030334 289 0.158
Human
regulation of camp mediated signaling GO:0043949 13 0.157
immune system development GO:0002520 195 0.155
positive regulation of camp metabolic process GO:0030816 41 0.149
cellular response to oxygen containing compound GO:1901701 276 0.147
Human
cell chemotaxis GO:0060326 112 0.147
regulation of apoptotic signaling pathway GO:2001233 175 0.145
cellular ion homeostasis GO:0006873 168 0.144
Human
regulation of purine nucleotide metabolic process GO:1900542 264 0.142
regulation of cell adhesion GO:0030155 166 0.141
negative regulation of vasculature development GO:1901343 43 0.140
positive regulation of behavior GO:0048520 60 0.138
positive regulation of cytokine production GO:0001819 167 0.138
cellular divalent inorganic cation homeostasis GO:0072503 128 0.137
Human
positive regulation of developmental process GO:0051094 314 0.137
vesicle mediated transport GO:0016192 371 0.132
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.132
cellular response to cytokine stimulus GO:0071345 181 0.132
sequestering of calcium ion GO:0051208 17 0.130
positive regulation of cyclic nucleotide metabolic process GO:0030801 49 0.129
positive regulation of transport GO:0051050 336 0.127
Human
neutrophil migration GO:1990266 25 0.126
myeloid leukocyte migration GO:0097529 62 0.125
negative regulation of multicellular organismal process GO:0051241 317 0.123
negative regulation of blood vessel morphogenesis GO:2000181 41 0.123
regulation of leukocyte migration GO:0002685 63 0.121
Human
positive regulation of immune system process GO:0002684 283 0.120
regulation of cellular amino acid metabolic process GO:0006521 6 0.119
single organismal cell cell adhesion GO:0016337 148 0.118
regulation of nucleotide metabolic process GO:0006140 269 0.118
single organism cell adhesion GO:0098602 179 0.117
extrinsic apoptotic signaling pathway GO:0097191 119 0.117
regulation of anatomical structure morphogenesis GO:0022603 286 0.114
regulation of sequestering of calcium ion GO:0051282 41 0.114
Human
taxis GO:0042330 157 0.114
positive regulation of nucleotide metabolic process GO:0045981 230 0.113
negative regulation of programmed cell death GO:0043069 321 0.112
cellular response to molecule of bacterial origin GO:0071219 62 0.111
Human
cellular amine metabolic process GO:0044106 41 0.110
regulation of angiogenesis GO:0045765 92 0.110
regulation of chemotaxis GO:0050920 74 0.108
regulation of cytokine production GO:0001817 232 0.105
granulocyte chemotaxis GO:0071621 37 0.102
wound healing GO:0042060 115 0.102
chemical homeostasis GO:0048878 306 0.101
Human
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.101
receptor internalization GO:0031623 43 0.095
metal ion homeostasis GO:0055065 169 0.094
Human
cytokine mediated signaling pathway GO:0019221 109 0.093
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.091
Human
cellular response to lipopolysaccharide GO:0071222 57 0.090
Human
cellular metal ion homeostasis GO:0006875 146 0.088
Human
positive regulation of response to external stimulus GO:0032103 88 0.088
ion homeostasis GO:0050801 230 0.088
Human
regulation of cell cycle GO:0051726 393 0.087
blood vessel morphogenesis GO:0048514 162 0.087
cation homeostasis GO:0055080 189 0.087
Human
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.086
regulation of tumor necrosis factor production GO:0032680 43 0.084
positive regulation of cellular component movement GO:0051272 181 0.083
Human
cellular cation homeostasis GO:0030003 163 0.082
Human
vasculature development GO:0001944 181 0.080
positive regulation of cellular component organization GO:0051130 376 0.078
tube development GO:0035295 125 0.078
positive regulation of cell death GO:0010942 263 0.078
homotypic cell cell adhesion GO:0034109 47 0.077
amine metabolic process GO:0009308 44 0.076
viral life cycle GO:0019058 132 0.075
regulation of cell differentiation GO:0045595 393 0.073
cytosolic calcium ion homeostasis GO:0051480 89 0.073
Human
positive regulation of cytoplasmic transport GO:1903651 82 0.072
Human
leukocyte migration involved in inflammatory response GO:0002523 2 0.072
defense response GO:0006952 315 0.071
cytoplasmic transport GO:0016482 379 0.071
Human
interspecies interaction between organisms GO:0044419 156 0.070
response to endoplasmic reticulum stress GO:0034976 49 0.069
cellular homeostasis GO:0019725 196 0.069
Human
cellular chemical homeostasis GO:0055082 180 0.069
Human
leukocyte chemotaxis GO:0030595 76 0.069
positive regulation of cellular amine metabolic process GO:0033240 7 0.068
multi organism cellular process GO:0044764 156 0.068
positive regulation of locomotion GO:0040017 186 0.067
Human
negative regulation of cell differentiation GO:0045596 171 0.067
positive regulation of hydrolase activity GO:0051345 331 0.067
positive regulation of cell differentiation GO:0045597 211 0.065
divalent metal ion transport GO:0070838 152 0.064
Human
positive regulation of cell migration GO:0030335 172 0.063
Human
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.063
positive regulation of cell proliferation GO:0008284 301 0.063
digestive tract development GO:0048565 75 0.063
multi organism metabolic process GO:0044033 41 0.062
erythrocyte development GO:0048821 3 0.062
regulation of ion transport GO:0043269 189 0.062
Human
viral process GO:0016032 146 0.061
camp mediated signaling GO:0019933 23 0.060
positive regulation of leukocyte migration GO:0002687 46 0.060
Human
cation transport GO:0006812 331 0.060
Human
regulation of cellular amine metabolic process GO:0033238 11 0.060
positive regulation of ion transport GO:0043270 87 0.059
Human
regulation of vasculature development GO:1901342 97 0.059
positive regulation of intracellular transport GO:0032388 104 0.059
Human
response to growth factor GO:0070848 205 0.059
negative regulation of cell proliferation GO:0008285 228 0.059
divalent inorganic cation homeostasis GO:0072507 136 0.058
Human
cyclic nucleotide metabolic process GO:0009187 82 0.058
immune response GO:0006955 307 0.058
Rat
cellular amino acid metabolic process GO:0006520 116 0.058
regulation of intracellular transport GO:0032386 195 0.055
Human
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 22 0.055
receptor metabolic process GO:0043112 81 0.055
angiogenesis GO:0001525 147 0.054
regulation of ion homeostasis GO:2000021 73 0.054
Human
regulation of multi organism process GO:0043900 157 0.053
regulation of cytoplasmic transport GO:1903649 149 0.053
Human
cellular response to lipid GO:0071396 127 0.052
Human
response to wounding GO:0009611 168 0.051
divalent inorganic cation transport GO:0072511 158 0.051
Human
myeloid leukocyte differentiation GO:0002573 60 0.051
intrinsic apoptotic signaling pathway GO:0097193 127 0.051
regulation of g protein coupled receptor protein signaling pathway GO:0008277 35 0.050
regulation of endopeptidase activity GO:0052548 170 0.050
positive regulation of programmed cell death GO:0043068 249 0.050
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.050
cell development GO:0048468 328 0.049
positive regulation of release of sequestered calcium ion into cytosol GO:0051281 16 0.049
Human
second messenger mediated signaling GO:0019932 78 0.049
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.049
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.049
negative regulation of apoptotic signaling pathway GO:2001234 97 0.049
positive regulation of apoptotic process GO:0043065 246 0.049
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 22 0.048
cellular ketone metabolic process GO:0042180 80 0.048
lipid metabolic process GO:0006629 381 0.048
cellular response to endogenous stimulus GO:0071495 336 0.047
regulation of proteolysis GO:0030162 293 0.047
negative regulation of catalytic activity GO:0043086 335 0.047
post embryonic development GO:0009791 2 0.046
cellular response to growth factor stimulus GO:0071363 197 0.046
regulation of homeostatic process GO:0032844 121 0.045
Human
regulation of hematopoietic progenitor cell differentiation GO:1901532 24 0.045
negative regulation of cell cycle GO:0045786 193 0.045
response to abiotic stimulus GO:0009628 336 0.045
maintenance of location GO:0051235 112 0.045
actin filament based process GO:0030029 224 0.044
protein maturation GO:0051604 233 0.044
protein oligomerization GO:0051259 173 0.044
protein processing GO:0016485 226 0.044
regulation of cellular ketone metabolic process GO:0010565 50 0.044
regulation of peptidase activity GO:0052547 180 0.043
regulation of myeloid cell differentiation GO:0045637 81 0.042
regulation of cellular component biogenesis GO:0044087 281 0.042
regulation of dna metabolic process GO:0051052 153 0.042
response to lipopolysaccharide GO:0032496 70 0.041
Human
regulation of macrophage derived foam cell differentiation GO:0010743 14 0.041
negative regulation of cellular protein metabolic process GO:0032269 353 0.041
positive regulation of organelle organization GO:0010638 195 0.041
cellular response to tumor necrosis factor GO:0071356 63 0.041
regulation of establishment of protein localization GO:0070201 242 0.041
response to tumor necrosis factor GO:0034612 76 0.040
ras protein signal transduction GO:0007265 73 0.040
positive regulation of calcium ion transport GO:0051928 51 0.040
Human
camp metabolic process GO:0046058 61 0.039
negative regulation of myeloid cell differentiation GO:0045638 42 0.039
defense response to bacterium GO:0042742 63 0.038
organophosphate catabolic process GO:0046434 430 0.038
nucleoside triphosphate metabolic process GO:0009141 422 0.038
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.038
organonitrogen compound biosynthetic process GO:1901566 200 0.037
single organism membrane organization GO:0044802 268 0.037
negative regulation of cellular component organization GO:0051129 235 0.037
epithelium migration GO:0090132 119 0.037
response to interleukin 1 GO:0070555 47 0.037
cellular lipid metabolic process GO:0044255 303 0.037
regulation of viral process GO:0050792 103 0.036
nucleoside catabolic process GO:0009164 408 0.036
female gamete generation GO:0007292 2 0.036
secretion GO:0046903 254 0.036
determination of adult lifespan GO:0008340 2 0.035
neutrophil chemotaxis GO:0030593 24 0.035
positive regulation of cellular component biogenesis GO:0044089 158 0.035
cell morphogenesis GO:0000902 296 0.035
response to molecule of bacterial origin GO:0002237 82 0.035
Human
behavior GO:0007610 112 0.035
metal ion transport GO:0030001 272 0.035
Human
carbohydrate derivative biosynthetic process GO:1901137 207 0.035
regulation of response to wounding GO:1903034 101 0.035
cellular response to interleukin 1 GO:0071347 35 0.034
regulation of defense response GO:0031347 154 0.034
inflammatory response GO:0006954 79 0.034
regulation of release of sequestered calcium ion into cytosol GO:0051279 27 0.034
Human
positive regulation of protein phosphorylation GO:0001934 313 0.034
purine ribonucleoside metabolic process GO:0046128 437 0.034
innate immune response GO:0045087 178 0.034
small molecule biosynthetic process GO:0044283 157 0.034
positive regulation of macrophage differentiation GO:0045651 7 0.034
ameboidal type cell migration GO:0001667 135 0.034
system process GO:0003008 349 0.034
mitotic cell cycle GO:0000278 326 0.033
regulation of macrophage differentiation GO:0045649 9 0.033
endocytosis GO:0006897 159 0.033
secretion by cell GO:0032940 226 0.033
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.032
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.032
cellular response to oxidative stress GO:0034599 85 0.032
oogenesis GO:0048477 2 0.032
alcohol metabolic process GO:0006066 114 0.032
purine nucleoside triphosphate metabolic process GO:0009144 412 0.032
regulation of myeloid leukocyte differentiation GO:0002761 39 0.032
calcium ion transport GO:0006816 147 0.032
Human
positive regulation of camp mediated signaling GO:0043950 10 0.032
hematopoietic progenitor cell differentiation GO:0002244 38 0.032
positive regulation of positive chemotaxis GO:0050927 13 0.031
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.031
nucleoside phosphate catabolic process GO:1901292 412 0.031
carbohydrate metabolic process GO:0005975 207 0.031
small gtpase mediated signal transduction GO:0007264 78 0.031
negative regulation of cell motility GO:2000146 104 0.030
regulation of viral genome replication GO:0045069 48 0.030
regulation of protein localization GO:0032880 296 0.030
multicellular organismal aging GO:0010259 3 0.030
single organism cellular localization GO:1902580 332 0.030
nucleoside triphosphate catabolic process GO:0009143 394 0.030
foam cell differentiation GO:0090077 15 0.029
nervous system development GO:0007399 293 0.029
cellular component morphogenesis GO:0032989 314 0.029
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 18 0.029
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.029
regulation of leukocyte differentiation GO:1902105 61 0.028
embryo development GO:0009790 123 0.028
response to fibroblast growth factor GO:0071774 39 0.028
ribonucleotide catabolic process GO:0009261 405 0.028
negative regulation of protein metabolic process GO:0051248 391 0.028
nucleotide catabolic process GO:0009166 408 0.028
response to decreased oxygen levels GO:0036293 96 0.028
regulation of actin filament based process GO:0032970 141 0.028
cell morphogenesis involved in differentiation GO:0000904 144 0.028
positive regulation of myeloid cell differentiation GO:0045639 39 0.028
response to hypoxia GO:0001666 96 0.028
purine ribonucleoside catabolic process GO:0046130 398 0.028
negative regulation of hematopoietic progenitor cell differentiation GO:1901533 18 0.027
actin cytoskeleton organization GO:0030036 207 0.027
chemokine mediated signaling pathway GO:0070098 16 0.027
Human
negative regulation of cellular component movement GO:0051271 106 0.027
defense response to fungus GO:0050832 4 0.027
cellular response to hydrogen peroxide GO:0070301 37 0.027
cell type specific apoptotic process GO:0097285 125 0.027
glycoprotein metabolic process GO:0009100 110 0.027
regulation of cell morphogenesis GO:0022604 153 0.026
i kappab kinase nf kappab signaling GO:0007249 166 0.026
purine containing compound catabolic process GO:0072523 411 0.026
viral genome replication GO:0019079 50 0.026
negative regulation of phosphorus metabolic process GO:0010563 267 0.026
reactive oxygen species metabolic process GO:0072593 75 0.026
cell projection organization GO:0030030 252 0.026
ribonucleoside catabolic process GO:0042454 406 0.026
positive regulation of catabolic process GO:0009896 310 0.026
regulation of cell activation GO:0050865 125 0.026
mitotic cell cycle process GO:1903047 286 0.026
regulation of secretion GO:0051046 194 0.026
regulation of sensory perception of pain GO:0051930 3 0.025
rho protein signal transduction GO:0007266 26 0.025
ribonucleoside triphosphate catabolic process GO:0009203 391 0.025
regulation of calcium ion transport into cytosol GO:0010522 33 0.025
Human
one carbon compound transport GO:0019755 4 0.025
positive regulation of myeloid leukocyte differentiation GO:0002763 24 0.025
regulation of actin cytoskeleton organization GO:0032956 116 0.025
motor neuron axon guidance GO:0008045 2 0.025
eosinophil differentiation GO:0030222 2 0.025
cytolysis GO:0019835 8 0.025
regulation of positive chemotaxis GO:0050926 14 0.025
ribonucleoside triphosphate metabolic process GO:0009199 412 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.025
central nervous system development GO:0007417 123 0.025
protein secretion GO:0009306 98 0.024
cellular response to biotic stimulus GO:0071216 71 0.024
Human
positive regulation of immune response GO:0050778 159 0.024
positive regulation of cellular catabolic process GO:0031331 284 0.024
chromatin organization GO:0006325 351 0.024
negative regulation of angiogenesis GO:0016525 39 0.024
regulation of thyroid hormone generation GO:2000609 2 0.024
purine nucleoside catabolic process GO:0006152 398 0.024
purine nucleoside triphosphate catabolic process GO:0009146 392 0.024
organophosphate biosynthetic process GO:0090407 163 0.024
regulation of cytoskeleton organization GO:0051493 177 0.024
regulation of secretion by cell GO:1903530 177 0.024
transmembrane transport GO:0055085 399 0.024
cell differentiation in spinal cord GO:0021515 1 0.024
cell substrate adhesion GO:0031589 132 0.023
regulation of cellular response to stress GO:0080135 244 0.023
response to inorganic substance GO:0010035 127 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.023
calcium ion homeostasis GO:0055074 122 0.023
Human
glycosyl compound catabolic process GO:1901658 413 0.023
purine nucleotide catabolic process GO:0006195 405 0.023
glycerolipid metabolic process GO:0046486 107 0.023
regulation of cysteine type endopeptidase activity GO:2000116 127 0.023
epithelial cell migration GO:0010631 119 0.023
guanosine containing compound catabolic process GO:1901069 239 0.023
cell division GO:0051301 168 0.023
memory GO:0007613 3 0.023
positive regulation of phosphorylation GO:0042327 394 0.023
regulation of myeloid leukocyte mediated immunity GO:0002886 4 0.023
actin filament organization GO:0007015 128 0.023
regulation of immune response GO:0050776 201 0.023
negative regulation of phosphate metabolic process GO:0045936 267 0.022
locomotory behavior GO:0007626 1 0.022
basophil differentiation GO:0030221 2 0.022
tissue migration GO:0090130 119 0.022
dephosphorylation GO:0016311 209 0.022
tumor necrosis factor production GO:0032640 43 0.022
response to oxygen levels GO:0070482 100 0.022
negative regulation of cell migration GO:0030336 102 0.022
leukocyte differentiation GO:0002521 98 0.022
regulation of protein transport GO:0051223 213 0.022
organic hydroxy compound metabolic process GO:1901615 147 0.022
regulation of epithelial cell proliferation GO:0050678 113 0.022
glycoprotein biosynthetic process GO:0009101 91 0.022
negative regulation of cellular amine metabolic process GO:0033239 3 0.022
response to fungus GO:0009620 4 0.021
negative regulation of locomotion GO:0040013 118 0.021
membrane organization GO:0061024 292 0.021
blood circulation GO:0008015 113 0.021
protein localization to membrane GO:0072657 160 0.021
positive regulation of leukocyte chemotaxis GO:0002690 38 0.021
leukocyte activation GO:0045321 164 0.021
regulation of protein processing GO:0070613 150 0.021
guanosine containing compound metabolic process GO:1901068 244 0.021
cellular macromolecule catabolic process GO:0044265 380 0.021
mature dendritic cell differentiation GO:0097029 2 0.021
cyclic nucleotide mediated signaling GO:0019935 26 0.021
regulation of protein complex assembly GO:0043254 147 0.021
posttranscriptional regulation of gene expression GO:0010608 213 0.021
regulation of mitotic cell cycle GO:0007346 189 0.020
positive regulation of protein transport GO:0051222 135 0.020
protein localization to organelle GO:0033365 280 0.020
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.020
endothelial cell migration GO:0043542 86 0.020
spinal cord development GO:0021510 4 0.020
hydrogen peroxide metabolic process GO:0042743 20 0.020
outflow tract septum morphogenesis GO:0003148 4 0.020
regulation of leukocyte chemotaxis GO:0002688 46 0.020
regulation of neural precursor cell proliferation GO:2000177 4 0.020
neuromuscular junction development GO:0007528 3 0.020
epithelium development GO:0060429 227 0.020
regulation of protein maturation GO:1903317 150 0.020
positive regulation of cell adhesion GO:0045785 84 0.020
positive regulation of proteolysis GO:0045862 142 0.020
organ morphogenesis GO:0009887 147 0.020
lipid biosynthetic process GO:0008610 177 0.019
megakaryocyte differentiation GO:0030219 25 0.019
epithelial cell proliferation GO:0050673 128 0.019
regulation of transferase activity GO:0051338 355 0.019
positive regulation of peptidase activity GO:0010952 88 0.019
regulation of megakaryocyte differentiation GO:0045652 22 0.019
defense response to other organism GO:0098542 129 0.019
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.019
regulation of vesicle mediated transport GO:0060627 130 0.019
regulation of nucleotide catabolic process GO:0030811 205 0.019
segmentation GO:0035282 4 0.019
positive regulation of aldosterone metabolic process GO:0032346 2 0.019
release of sequestered calcium ion into cytosol GO:0051209 41 0.019
Human
regeneration GO:0031099 4 0.019
brain development GO:0007420 97 0.019
covalent chromatin modification GO:0016569 254 0.019
oocyte development GO:0048599 1 0.019
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.019
response to oxidative stress GO:0006979 121 0.019
cell cycle arrest GO:0007050 71 0.019
regulation of protein secretion GO:0050708 86 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.019
negative regulation of blood pressure GO:0045776 3 0.019
regulation of kinase activity GO:0043549 314 0.019
cytosolic calcium ion transport GO:0060401 48 0.018
Human
negative regulation of hydrolase activity GO:0051346 182 0.018
oxidation reduction process GO:0055114 396 0.018
regulation of single stranded viral rna replication via double stranded dna intermediate GO:0045091 8 0.018
positive regulation of endopeptidase activity GO:0010950 84 0.018
single organism carbohydrate metabolic process GO:0044723 193 0.018
negative regulation of immune system process GO:0002683 136 0.018
positive regulation of epithelial cell proliferation involved in wound healing GO:0060054 3 0.018
cellular response to dna damage stimulus GO:0006974 379 0.018
negative regulation of protein processing GO:0010955 142 0.018
nitrogen compound transport GO:0071705 191 0.018
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.018
immune response activating signal transduction GO:0002757 90 0.018
positive regulation of aldosterone biosynthetic process GO:0032349 2 0.018
protein catabolic process GO:0030163 325 0.018
regulation of ras protein signal transduction GO:0046578 155 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.018
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.018
regulation of hemostasis GO:1900046 42 0.017
negative regulation of intracellular signal transduction GO:1902532 183 0.017
positive regulation of cytoskeleton organization GO:0051495 83 0.017
negative regulation of protein modification process GO:0031400 200 0.017
signal transduction in absence of ligand GO:0038034 22 0.017
disruption by host of symbiont cells GO:0051852 2 0.017
establishment of protein localization to membrane GO:0090150 121 0.017
organic anion transport GO:0015711 103 0.017
positive regulation of calcium ion transport into cytosol GO:0010524 20 0.017
Human
regulation of cell cycle process GO:0010564 266 0.017
gtp catabolic process GO:0006184 237 0.017
negative regulation of protein maturation GO:1903318 142 0.017
reactive oxygen species biosynthetic process GO:1903409 4 0.017
gtp metabolic process GO:0046039 239 0.017
negative regulation of peptidase activity GO:0010466 91 0.017
regulation of ras gtpase activity GO:0032318 128 0.017
anion transport GO:0006820 161 0.017
endomembrane system organization GO:0010256 196 0.017
single stranded viral rna replication via double stranded dna intermediate GO:0039692 9 0.017
regulation of purine nucleotide catabolic process GO:0033121 205 0.017
oocyte differentiation GO:0009994 2 0.016
negative regulation of eosinophil migration GO:2000417 2 0.016
negative regulation of cell adhesion GO:0007162 64 0.016
spermatid differentiation GO:0048515 4 0.016
regulation of epithelial cell migration GO:0010632 93 0.016
positive regulation of defense response GO:0031349 87 0.016
epithelial cell differentiation GO:0030855 141 0.016
purine ribonucleotide catabolic process GO:0009154 404 0.016
erythrocyte maturation GO:0043249 1 0.016
embryonic placenta development GO:0001892 1 0.016
phospholipid metabolic process GO:0006644 99 0.016
platelet aggregation GO:0070527 32 0.016
positive chemotaxis GO:0050918 33 0.016
regulation of nucleoside metabolic process GO:0009118 209 0.016
t cell differentiation in thymus GO:0033077 4 0.016
peptidyl tyrosine modification GO:0018212 170 0.016
cellular response to reactive oxygen species GO:0034614 50 0.016
endothelial cell proliferation GO:0001935 65 0.015
regulation of blood coagulation GO:0030193 42 0.015
receptor mediated endocytosis GO:0006898 84 0.015

PF4 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.216
hematopoietic system disease DOID:74 100 0.216
blood coagulation disease DOID:1247 21 0.046
disease of metabolism DOID:0014667 295 0.039
inherited metabolic disorder DOID:655 242 0.039
anemia DOID:2355 55 0.027
disease by infectious agent DOID:0050117 34 0.023
cancer DOID:162 167 0.023
disease of cellular proliferation DOID:14566 174 0.023
normocytic anemia DOID:720 20 0.022
sensory system disease DOID:0050155 203 0.021
nervous system disease DOID:863 431 0.021
organ system cancer DOID:0050686 164 0.021
hemolytic anemia DOID:583 20 0.021
eye and adnexa disease DOID:1492 150 0.019
eye disease DOID:5614 149 0.018
parasitic infectious disease DOID:1398 16 0.016
inherited blood coagulation disease DOID:2214 13 0.016