IMP

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Homo sapiens

33 genes annotated in human

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positive chemotaxis

GO:0050918

The directed movement of a motile cell or organism towards a higher concentration of a chemical.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive chemotaxis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive chemotaxis" (in gray)

Name	Description	Probability	Func Analog Organism
EGFR	epidermal growth factor receptor	1.000
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.978
FGFR2	fibroblast growth factor receptor 2	0.966
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.963	Human
VEGFA	vascular endothelial growth factor A	0.949
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.920	Human
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.920	Human
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.883
TEK	TEK tyrosine kinase, endothelial	0.852
CCR5	chemokine (C-C motif) receptor 5	0.797
DPP4	dipeptidyl-peptidase 4	0.796
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.722
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.676
PLCG1	phospholipase C, gamma 1	0.661
FGFR1	fibroblast growth factor receptor 1	0.650
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.580
SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.567
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.560
LAT	linker for activation of T cells	0.549
IL8	interleukin 8	0.548
FGF1	fibroblast growth factor 1 (acidic)	0.546	Human
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.520
PTPRC	protein tyrosine phosphatase, receptor type, C	0.474
SEMA4A	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A	0.373	Fly
CXCL2	chemokine (C-X-C motif) ligand 2	0.370	Human
CDH5	cadherin 5, type 2 (vascular endothelium)	0.369
GAB1	GRB2-associated binding protein 1	0.348
NRP1	neuropilin 1	0.317	Mouse
CXCL3	chemokine (C-X-C motif) ligand 3	0.307	Human
CXCL10	chemokine (C-X-C motif) ligand 10	0.296	Human
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.282	Human
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.235	Human
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.224
CCL8	chemokine (C-C motif) ligand 8	0.223	Human
CCL2	chemokine (C-C motif) ligand 2	0.222	Human
CTNND1	catenin (cadherin-associated protein), delta 1	0.217
PLXNB1	plexin B1	0.211	Human
CXCL9	chemokine (C-X-C motif) ligand 9	0.178	Human
CCL5	chemokine (C-C motif) ligand 5	0.172
NTRK2	neurotrophic tyrosine kinase, receptor, type 2	0.157	Human
BMPR1A	bone morphogenetic protein receptor, type IA	0.148
FN1	fibronectin 1	0.143
CCL20	chemokine (C-C motif) ligand 20	0.141	Human
GRB7	growth factor receptor-bound protein 7	0.130
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.128	Human
CXCL11	chemokine (C-X-C motif) ligand 11	0.125	Human
CALCOCO2	calcium binding and coiled-coil domain 2	0.119
CCL4	chemokine (C-C motif) ligand 4	0.118	Human
CNKSR2	connector enhancer of kinase suppressor of Ras 2	0.114
APC	adenomatous polyposis coli	0.114
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.111
DSG2	desmoglein 2	0.111
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.107
SOS1	son of sevenless homolog 1 (Drosophila)	0.105
FGF10	fibroblast growth factor 10	0.105
RND1	Rho family GTPase 1	0.105
GHR	growth hormone receptor	0.099
ARHGEF11	Rho guanine nucleotide exchange factor (GEF) 11	0.096
IL6	interleukin 6 (interferon, beta 2)	0.094
FGA	fibrinogen alpha chain	0.093
TGIF1	TGFB-induced factor homeobox 1	0.090
GAS6	growth arrest-specific 6	0.089
CCL19	chemokine (C-C motif) ligand 19	0.086	Human
CCL3	chemokine (C-C motif) ligand 3	0.079
CAV1	caveolin 1, caveolae protein, 22kDa	0.075
IL1B	interleukin 1, beta	0.071
PLAU	plasminogen activator, urokinase	0.068	Human
VCAM1	vascular cell adhesion molecule 1	0.066
PLAT	plasminogen activator, tissue	0.065	Human
PGF	placental growth factor	0.064	Human
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.064
FGF7	fibroblast growth factor 7	0.062
CCR7	chemokine (C-C motif) receptor 7	0.062
PDGFC	platelet derived growth factor C	0.061
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.061
CSNK1A1	casein kinase 1, alpha 1	0.061
CCL7	chemokine (C-C motif) ligand 7	0.060	Human
CCR2	chemokine (C-C motif) receptor 2	0.059
S100B	S100 calcium binding protein B	0.051
DPYSL4	dihydropyrimidinase-like 4	0.050
CXCL5	chemokine (C-X-C motif) ligand 5	0.050	Human
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.049
CXCL13	chemokine (C-X-C motif) ligand 13	0.048
CCR1	chemokine (C-C motif) receptor 1	0.047
PLXND1	plexin D1	0.046	Human
ALB	albumin	0.046
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.044
UBD	ubiquitin D	0.042
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.042
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.042
ANGPT2	angiopoietin 2	0.041
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.041
PLXNB2	plexin B2	0.040	Human
PDGFA	platelet-derived growth factor alpha polypeptide	0.040	Human
CCL13	chemokine (C-C motif) ligand 13	0.039	Human
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.039
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.037
CCL14	chemokine (C-C motif) ligand 14	0.037	Human
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.037	Human
IFNG	interferon, gamma	0.036
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.036	Human
HSPG2	heparan sulfate proteoglycan 2	0.036
ANGPT1	angiopoietin 1	0.035
NTF4	neurotrophin 4	0.034	Human
NGF	nerve growth factor (beta polypeptide)	0.034	Human
TSC1	tuberous sclerosis 1	0.034
OSMR	oncostatin M receptor	0.034
PTPRB	protein tyrosine phosphatase, receptor type, B	0.033	Human
VEGFC	vascular endothelial growth factor C	0.033
NRP2	neuropilin 2	0.033
PSEN1	presenilin 1	0.032
FYN	FYN oncogene related to SRC, FGR, YES	0.032
PKP4	plakophilin 4	0.031
FLNA	filamin A, alpha	0.031
MMP1	matrix metallopeptidase 1 (interstitial collagenase)	0.031
FGF8	fibroblast growth factor 8 (androgen-induced)	0.030	Rat
MICA	MHC class I polypeptide-related sequence A	0.029
IL7R	interleukin 7 receptor	0.028
ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	0.027
HGF	hepatocyte growth factor (hepapoietin A; scatter factor)	0.027
LDLR	low density lipoprotein receptor	0.027
BDNF	brain-derived neurotrophic factor	0.026	Human
PTMA	prothymosin, alpha	0.026
SLA	Src-like-adaptor	0.025
DARC	Duffy blood group, chemokine receptor	0.025
INHBA	inhibin, beta A	0.024
TMSB10	thymosin beta 10	0.024
MST1R	macrophage stimulating 1 receptor (c-met-related tyrosine kinase)	0.024	Human
TIMP1	TIMP metallopeptidase inhibitor 1	0.024
CCL22	chemokine (C-C motif) ligand 22	0.024	Human
NTF3	neurotrophin 3	0.024
KITLG	KIT ligand	0.024
COL5A1	collagen, type V, alpha 1	0.023
BCAR1	breast cancer anti-estrogen resistance 1	0.022
CD69	CD69 molecule	0.021
CD22	CD22 molecule	0.021
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.021
DPT	dermatopontin	0.021
CCR4	chemokine (C-C motif) receptor 4	0.020	Rat
HMGB2	high mobility group box 2	0.020
TPM4	tropomyosin 4	0.020
COL6A1	collagen, type VI, alpha 1	0.020
RANBP9	RAN binding protein 9	0.020
ROBO4	roundabout homolog 4, magic roundabout (Drosophila)	0.020
CD2	CD2 molecule	0.019
DUT	deoxyuridine triphosphatase	0.019
ITGB4	integrin, beta 4	0.019
PLAUR	plasminogen activator, urokinase receptor	0.019
IL2RB	interleukin 2 receptor, beta	0.019
VKORC1	vitamin K epoxide reductase complex, subunit 1	0.019
FGF2	fibroblast growth factor 2 (basic)	0.018
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.018	Rat
CH25H	cholesterol 25-hydroxylase	0.018
TXN	thioredoxin	0.018
ADAMDEC1	ADAM-like, decysin 1	0.018
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.017
CD163	CD163 molecule	0.017
PXN	paxillin	0.017
BTRC	beta-transducin repeat containing	0.017
SRGN	serglycin	0.017
KNG1	kininogen 1	0.017
SELE	selectin E	0.017
SLIT2	slit homolog 2 (Drosophila)	0.016
WNT1	wingless-type MMTV integration site family, member 1	0.016
ITGA6	integrin, alpha 6	0.016
ANXA2	annexin A2	0.016
PHLDA1	pleckstrin homology-like domain, family A, member 1	0.016
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.016	Human
EMD	emerin	0.016
RGS16	regulator of G-protein signaling 16	0.016
CD40LG	CD40 ligand	0.016
TGFB2	transforming growth factor, beta 2	0.016
FPR3	formyl peptide receptor 3	0.016
CD63	CD63 molecule	0.016
PF4	platelet factor 4	0.016
MSC	musculin	0.016
SH3RF1	SH3 domain containing ring finger 1	0.015
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.015
TNF	tumor necrosis factor	0.015
DCN	decorin	0.015
WDYHV1	WDYHV motif containing 1	0.015
CLEC10A	C-type lectin domain family 10, member A	0.015
CXCR3	chemokine (C-X-C motif) receptor 3	0.015
TFPI2	tissue factor pathway inhibitor 2	0.015
ZFYVE9	zinc finger, FYVE domain containing 9	0.015
DSP	desmoplakin	0.015
CTGF	connective tissue growth factor	0.015
CRMP1	collapsin response mediator protein 1	0.015
WIPI1	WD repeat domain, phosphoinositide interacting 1	0.015
RGS1	regulator of G-protein signaling 1	0.015
HLA-DRA	major histocompatibility complex, class II, DR alpha	0.015
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.015
TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.015
SPRY4	sprouty homolog 4 (Drosophila)	0.015
LAMP3	lysosomal-associated membrane protein 3	0.015
VCL	vinculin	0.014
STC1	stanniocalcin 1	0.014
CTTN	cortactin	0.014
ENO1	enolase 1, (alpha)	0.014
S100A4	S100 calcium binding protein A4	0.014
PTPRD	protein tyrosine phosphatase, receptor type, D	0.014
FLT4	fms-related tyrosine kinase 4	0.014	Human
TRAF3IP3	TRAF3 interacting protein 3	0.014
LGALS1	lectin, galactoside-binding, soluble, 1	0.014	Human
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.013
KIAA1199	KIAA1199	0.013
CA12	carbonic anhydrase XII	0.013
ICAM1	intercellular adhesion molecule 1	0.013
CSK	c-src tyrosine kinase	0.013
CDC34	cell division cycle 34 homolog (S. cerevisiae)	0.013
CD83	CD83 molecule	0.013
CCL11	chemokine (C-C motif) ligand 11	0.013	Human
FGFBP1	fibroblast growth factor binding protein 1	0.013
IL1A	interleukin 1, alpha	0.012
EVI2A	ecotropic viral integration site 2A	0.012
HMGB1	high mobility group box 1	0.012	Human
CCR3	chemokine (C-C motif) receptor 3	0.012
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.012
NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1	0.012
LAMC2	laminin, gamma 2	0.012
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.012
TLN1	talin 1	0.012
TNC	tenascin C	0.012
STX8	syntaxin 8	0.012
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.012
NGFR	nerve growth factor receptor	0.012
TTR	transthyretin	0.012
DST	dystonin	0.012
SHC3	SHC (Src homology 2 domain containing) transforming protein 3	0.012
IL11	interleukin 11	0.012
C7	complement component 7	0.012
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.012
PLA2G7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	0.012
IDO1	indoleamine 2,3-dioxygenase 1	0.012
FGFR3	fibroblast growth factor receptor 3	0.012
CXCR6	chemokine (C-X-C motif) receptor 6	0.012
A1BG	alpha-1-B glycoprotein	0.011
PVR	poliovirus receptor	0.011
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.011
LAMB3	laminin, beta 3	0.011
ANP32E	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E	0.011
RICTOR	RPTOR independent companion of MTOR, complex 2	0.011
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.011
IRF8	interferon regulatory factor 8	0.011
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.011
STAB2	stabilin 2	0.011
CSF1	colony stimulating factor 1 (macrophage)	0.011
MMP7	matrix metallopeptidase 7 (matrilysin, uterine)	0.011
WNT2	wingless-type MMTV integration site family member 2	0.011
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.011
MMP10	matrix metallopeptidase 10 (stromelysin 2)	0.011
IDE	insulin-degrading enzyme	0.011
OLR1	oxidized low density lipoprotein (lectin-like) receptor 1	0.011
SRPX	sushi-repeat containing protein, X-linked	0.011
CD4	CD4 molecule	0.011
SERPINF2	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2	0.011
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.011
IL18R1	interleukin 18 receptor 1	0.011
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.011
TLR2	toll-like receptor 2	0.010
XCL1	chemokine (C motif) ligand 1	0.010	Human
PTHLH	parathyroid hormone-like hormone	0.010
TCF4	transcription factor 4	0.010
C2	complement component 2	0.010
MOBKL2B	MOB1, Mps One Binder kinase activator-like 2B (yeast)	0.010
NKG7	natural killer cell group 7 sequence	0.010
IL2RG	interleukin 2 receptor, gamma	0.010
GLIS2	GLIS family zinc finger 2	0.010
SYK	spleen tyrosine kinase	0.010
FGG	fibrinogen gamma chain	0.010
ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	0.010	Rat
SLAMF8	SLAM family member 8	0.010
BCL2A1	BCL2-related protein A1	0.010
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.010