Homo sapiens

20 known processes

PLEC

plectin

(Aliases: PLEC1,HD1,PLEC1b,EBS1,PLTN,EBSO,PCN,LGMD2Q)

PLEC biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory perception of smell GO:0007608 2 0.989
regulation of cellular component biogenesis GO:0044087 281 0.931
Fly
actin filament organization GO:0007015 128 0.897
microtubule cytoskeleton organization GO:0000226 176 0.880
Human Fly
tube development GO:0035295 125 0.851
Fly
actin filament based process GO:0030029 224 0.850
purine nucleotide catabolic process GO:0006195 405 0.794
actin cytoskeleton organization GO:0030036 207 0.792
regulation of cytoskeleton organization GO:0051493 177 0.780
Fly
nucleoside triphosphate catabolic process GO:0009143 394 0.724
response to growth factor GO:0070848 205 0.706
cation transport GO:0006812 331 0.678
plasma membrane organization GO:0007009 115 0.671
Human
cell junction assembly GO:0034329 67 0.650
sensory perception of chemical stimulus GO:0007606 38 0.647
circulatory system development GO:0072359 262 0.645
cell matrix adhesion GO:0007160 85 0.638
multicellular organismal aging GO:0010259 3 0.622
biological adhesion GO:0022610 331 0.594
positive regulation of cellular component organization GO:0051130 376 0.579
Fly
glycosyl compound catabolic process GO:1901658 413 0.563
purine nucleoside catabolic process GO:0006152 398 0.556
regulation of cell differentiation GO:0045595 393 0.551
Fly
positive regulation of hydrolase activity GO:0051345 331 0.549
regulation of anatomical structure morphogenesis GO:0022603 286 0.530
Fly
metal ion transport GO:0030001 272 0.528
cellular response to growth factor stimulus GO:0071363 197 0.525
guanosine containing compound catabolic process GO:1901069 239 0.513
salivary gland morphogenesis GO:0007435 4 0.511
regulation of purine nucleotide metabolic process GO:1900542 264 0.496
purine containing compound catabolic process GO:0072523 411 0.493
determination of adult lifespan GO:0008340 2 0.483
regulation of locomotion GO:0040012 329 0.477
anatomical structure formation involved in morphogenesis GO:0048646 284 0.475
Fly
purine ribonucleoside metabolic process GO:0046128 437 0.474
purine nucleoside triphosphate metabolic process GO:0009144 412 0.467
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.459
pericardium development GO:0060039 2 0.456
regulation of cellular ketone metabolic process GO:0010565 50 0.454
system process GO:0003008 349 0.454
leukocyte migration GO:0050900 107 0.447
positive regulation of gtpase activity GO:0043547 166 0.445
endomembrane system organization GO:0010256 196 0.424
Human
regulation of actin cytoskeleton organization GO:0032956 116 0.424
organ morphogenesis GO:0009887 147 0.412
protein catabolic process GO:0030163 325 0.411
regulation of rho protein signal transduction GO:0035023 79 0.400
nucleoside catabolic process GO:0009164 408 0.396
single organism cellular localization GO:1902580 332 0.378
Human
regulation of actin filament bundle assembly GO:0032231 36 0.378
positive regulation of locomotion GO:0040017 186 0.371
regulation of gtpase activity GO:0043087 180 0.370
cellular amine metabolic process GO:0044106 41 0.367
nucleoside phosphate catabolic process GO:1901292 412 0.367
cation transmembrane transport GO:0098655 238 0.355
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.350
cell matrix adhesion involved in ameboidal cell migration GO:0003366 2 0.345
muscle structure development GO:0061061 98 0.328
cell adhesion GO:0007155 325 0.325
stem cell development GO:0048864 69 0.325
cell morphogenesis GO:0000902 296 0.323
Fly
purine ribonucleotide catabolic process GO:0009154 404 0.319
calcium ion transport GO:0006816 147 0.302
taxis GO:0042330 157 0.296
Fly
neurological system process GO:0050877 163 0.295
protein localization to membrane GO:0072657 160 0.295
Human
regulation of collagen catabolic process GO:0010710 3 0.288
single organism membrane organization GO:0044802 268 0.288
Human
actomyosin structure organization GO:0031032 59 0.284
organ formation GO:0048645 3 0.284
memory GO:0007613 3 0.283
regulation of actin filament polymerization GO:0030833 50 0.282
nucleoside triphosphate metabolic process GO:0009141 422 0.279
regulation of nucleotide catabolic process GO:0030811 205 0.275
sensory perception GO:0007600 103 0.272
positive regulation of cellular catabolic process GO:0031331 284 0.270
negative regulation of cellular component movement GO:0051271 106 0.262
muscle cell development GO:0055001 29 0.261
regulation of protein localization GO:0032880 296 0.259
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.259
guanosine containing compound metabolic process GO:1901068 244 0.257
immune response GO:0006955 307 0.256
protein localization to plasma membrane GO:0072659 93 0.255
Human
regulation of collagen metabolic process GO:0010712 15 0.254
regulation of small gtpase mediated signal transduction GO:0051056 156 0.253
regulation of cell migration GO:0030334 289 0.252
cell cell adhesion mediated by integrin GO:0033631 8 0.250
positive regulation of developmental process GO:0051094 314 0.247
Fly
regulation of nucleoside metabolic process GO:0009118 209 0.246
regulation of establishment of protein localization GO:0070201 242 0.242
establishment of protein localization to membrane GO:0090150 121 0.238
Human
ribonucleoside catabolic process GO:0042454 406 0.227
cell substrate junction assembly GO:0007044 35 0.225
ribonucleotide catabolic process GO:0009261 405 0.225
vesicle mediated transport GO:0016192 371 0.223
Human
muscle contraction GO:0006936 73 0.222
regulation of membrane potential GO:0042391 95 0.221
cellular extravasation GO:0045123 21 0.219
establishment of protein localization to plasma membrane GO:0090002 68 0.217
Human
post embryonic development GO:0009791 2 0.214
inorganic ion transmembrane transport GO:0098660 231 0.213
regulation of purine nucleotide catabolic process GO:0033121 205 0.212
response to transforming growth factor beta GO:0071559 94 0.212
endodermal cell differentiation GO:0035987 31 0.210
integrin mediated signaling pathway GO:0007229 32 0.205
actin filament bundle assembly GO:0051017 54 0.204
skin development GO:0043588 76 0.196
heart development GO:0007507 95 0.194
connective tissue development GO:0061448 39 0.194
chemical homeostasis GO:0048878 306 0.194
neuron projection development GO:0031175 106 0.192
Fly
enzyme linked receptor protein signaling pathway GO:0007167 303 0.192
muscle system process GO:0003012 81 0.191
ribonucleoside triphosphate metabolic process GO:0009199 412 0.190
stress fiber assembly GO:0043149 40 0.188
establishment of nucleus localization GO:0040023 1 0.187
nervous system development GO:0007399 293 0.185
Fly
organophosphate catabolic process GO:0046434 430 0.183
purine nucleoside triphosphate catabolic process GO:0009146 392 0.182
regulation of ras protein signal transduction GO:0046578 155 0.181
negative regulation of cell migration GO:0030336 102 0.180
positive regulation of cell proliferation GO:0008284 301 0.180
cellular component morphogenesis GO:0032989 314 0.176
Fly
regulation of cellular amino acid metabolic process GO:0006521 6 0.176
chemotaxis GO:0006935 157 0.173
Fly
regulation of cell shape GO:0008360 48 0.172
embryo development GO:0009790 123 0.172
regulation of protein kinase activity GO:0045859 289 0.170
gtp metabolic process GO:0046039 239 0.168
collagen catabolic process GO:0030574 10 0.168
cellular response to endogenous stimulus GO:0071495 336 0.166
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.165
actin filament bundle organization GO:0061572 54 0.165
hematopoietic or lymphoid organ development GO:0048534 186 0.165
cytoplasmic transport GO:0016482 379 0.163
Human
cardiovascular system development GO:0072358 262 0.161
microtubule organizing center organization GO:0031023 62 0.160
regulation of gtp catabolic process GO:0033124 180 0.159
cell development GO:0048468 328 0.158
Fly
endoderm formation GO:0001706 33 0.154
single organism cell adhesion GO:0098602 179 0.154
central nervous system development GO:0007417 123 0.151
Fly
neuron differentiation GO:0030182 138 0.151
Fly
small gtpase mediated signal transduction GO:0007264 78 0.150
post embryonic organ development GO:0048569 1 0.147
positive regulation of nucleotide metabolic process GO:0045981 230 0.147
regulation of actin filament based process GO:0032970 141 0.146
regulation of cell morphogenesis GO:0022604 153 0.140
Fly
stem cell differentiation GO:0048863 93 0.139
negative regulation of locomotion GO:0040013 118 0.139
regulation of kinase activity GO:0043549 314 0.136
negative regulation of cell motility GO:2000146 104 0.133
ameboidal type cell migration GO:0001667 135 0.133
response to hypoxia GO:0001666 96 0.132
regulation of protein localization to nucleus GO:1900180 85 0.132
positive regulation of apoptotic process GO:0043065 246 0.129
positive regulation of protein phosphorylation GO:0001934 313 0.126
muscle cell differentiation GO:0042692 63 0.126
endoderm development GO:0007492 33 0.126
mitotic cell cycle process GO:1903047 286 0.123
multicellular organismal macromolecule metabolic process GO:0044259 29 0.120
purine ribonucleoside catabolic process GO:0046130 398 0.120
intracellular protein transport GO:0006886 270 0.120
Human
cell junction organization GO:0034330 79 0.118
cell projection morphogenesis GO:0048858 129 0.118
Fly
positive regulation of catabolic process GO:0009896 310 0.117
receptor mediated endocytosis GO:0006898 84 0.117
mitotic cell cycle GO:0000278 326 0.117
positive regulation of cell differentiation GO:0045597 211 0.117
Fly
cell activation GO:0001775 213 0.117
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.114
positive regulation of nucleotide catabolic process GO:0030813 185 0.112
regulation of cell adhesion GO:0030155 166 0.110
tube morphogenesis GO:0035239 95 0.110
Fly
cell morphogenesis involved in differentiation GO:0000904 144 0.110
Fly
response to alcohol GO:0097305 64 0.109
ras protein signal transduction GO:0007265 73 0.108
regulation of nucleotide metabolic process GO:0006140 269 0.107
carbohydrate derivative biosynthetic process GO:1901137 207 0.105
wound healing GO:0042060 115 0.105
calcium independent cell matrix adhesion GO:0007161 1 0.104
actin filament polymerization GO:0030041 45 0.102
growth GO:0040007 202 0.101
Fly
cell substrate adhesion GO:0031589 132 0.101
cell adhesion mediated by integrin GO:0033627 27 0.101
regulation of stress fiber assembly GO:0051492 32 0.099
cell part morphogenesis GO:0032990 137 0.099
Fly
negative regulation of developmental process GO:0051093 247 0.098
urogenital system development GO:0001655 65 0.098
mesodermal cell differentiation GO:0048333 10 0.097
epithelium development GO:0060429 227 0.097
Rat Fly
regulation of actin polymerization or depolymerization GO:0008064 56 0.096
dendritic spine maintenance GO:0097062 1 0.096
microtubule based process GO:0007017 210 0.095
Human Fly
female gamete generation GO:0007292 2 0.094
generation of neurons GO:0048699 152 0.094
Fly
negative regulation of transport GO:0051051 176 0.094
negative regulation of protein metabolic process GO:0051248 391 0.093
nucleoside monophosphate metabolic process GO:0009123 191 0.093
cytokinesis GO:0000910 96 0.091
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.091
gtp catabolic process GO:0006184 237 0.090
anoikis GO:0043276 22 0.090
calcium ion transmembrane transport GO:0070588 76 0.089
renal system development GO:0072001 63 0.089
regulation of multicellular organismal metabolic process GO:0044246 17 0.089
positive regulation of cellular amine metabolic process GO:0033240 7 0.088
organelle assembly GO:0070925 176 0.088
regulation of protein complex assembly GO:0043254 147 0.088
motor neuron axon guidance GO:0008045 2 0.088
nucleocytoplasmic transport GO:0006913 176 0.087
rho protein signal transduction GO:0007266 26 0.087
nucleus localization GO:0051647 1 0.087
circulatory system process GO:0003013 113 0.087
neuron development GO:0048666 113 0.084
Fly
organonitrogen compound biosynthetic process GO:1901566 200 0.084
i kappab kinase nf kappab signaling GO:0007249 166 0.083
cell projection assembly GO:0030031 126 0.083
Fly
epithelial cell cell adhesion GO:0090136 7 0.083
inorganic cation transmembrane transport GO:0098662 194 0.082
leukocyte cell cell adhesion GO:0007159 37 0.081
ossification GO:0001503 121 0.080
digestive tract morphogenesis GO:0048546 56 0.079
cell cell junction organization GO:0045216 69 0.079
positive regulation of transferase activity GO:0051347 227 0.078
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 22 0.078
multicellular organismal metabolic process GO:0044236 34 0.077
cellular component assembly involved in morphogenesis GO:0010927 73 0.077
striated muscle contraction GO:0006941 52 0.075
ion transmembrane transport GO:0034220 338 0.075
regulation of actin filament length GO:0030832 56 0.075
organelle fission GO:0048285 149 0.075
positive regulation of cell death GO:0010942 263 0.074
positive regulation of cell motility GO:2000147 177 0.074
regulation of epithelial cell migration GO:0010632 93 0.074
positive regulation of cell adhesion GO:0045785 84 0.073
cell projection organization GO:0030030 252 0.073
Fly
response to decreased oxygen levels GO:0036293 96 0.072
regulation of tor signaling GO:0032006 30 0.070
spermatid development GO:0007286 4 0.070
cellular homeostasis GO:0019725 196 0.070
membrane organization GO:0061024 292 0.069
Human
regulation of growth GO:0040008 165 0.069
Fly
organophosphate biosynthetic process GO:0090407 163 0.069
positive regulation of organelle organization GO:0010638 195 0.069
skeletal system development GO:0001501 79 0.069
myosin filament assembly GO:0031034 2 0.067
positive regulation of protein localization to plasma membrane GO:1903078 20 0.066
mesenchymal cell differentiation GO:0048762 52 0.066
endocytosis GO:0006897 159 0.065
single organism nuclear import GO:1902593 104 0.065
regulation of protein transport GO:0051223 213 0.064
gastrulation GO:0007369 51 0.064
endothelial cell migration GO:0043542 86 0.063
protein targeting GO:0006605 187 0.063
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.062
positive regulation of protein kinase activity GO:0045860 190 0.062
muscle organ development GO:0007517 56 0.062
neurogenesis GO:0022008 169 0.061
Fly
regulation of wnt signaling pathway GO:0030111 123 0.060
lipoprotein metabolic process GO:0042157 42 0.059
regulation of cell motility GO:2000145 299 0.058
regulation of intracellular transport GO:0032386 195 0.058
autophagy GO:0006914 88 0.057
regulation of cell cycle GO:0051726 393 0.057
cell fate determination GO:0001709 3 0.057
Fly
establishment of organelle localization GO:0051656 59 0.056
exocrine system development GO:0035272 7 0.056
establishment of protein localization to organelle GO:0072594 172 0.056
protein localization to nucleus GO:0034504 136 0.055
cell chemotaxis GO:0060326 112 0.055
positive regulation of camp biosynthetic process GO:0030819 35 0.055
negative regulation of multicellular organismal process GO:0051241 317 0.055
morphogenesis of an epithelial sheet GO:0002011 12 0.054
morphogenesis of an epithelium GO:0002009 60 0.054
Fly
substrate adhesion dependent cell spreading GO:0034446 41 0.054
reproductive system development GO:0061458 56 0.053
negative regulation of organelle organization GO:0010639 126 0.053
Fly
actin polymerization or depolymerization GO:0008154 56 0.052
cellular macromolecular complex assembly GO:0034622 324 0.051
regulation of protein binding GO:0043393 66 0.050
regulation of cell cell adhesion GO:0022407 57 0.050
aging GO:0007568 66 0.050
nucleoside phosphate biosynthetic process GO:1901293 109 0.050
transmembrane transport GO:0055085 399 0.050
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.049
semaphorin plexin signaling pathway GO:0071526 4 0.049
cellular cation homeostasis GO:0030003 163 0.049
monovalent inorganic cation transport GO:0015672 128 0.048
regeneration GO:0031099 4 0.047
negative regulation of intracellular signal transduction GO:1902532 183 0.047
regulation of metal ion transport GO:0010959 120 0.047
positive regulation of kinase activity GO:0033674 204 0.047
negative regulation of programmed cell death GO:0043069 321 0.047
regulation of vesicle mediated transport GO:0060627 130 0.046
cognition GO:0050890 43 0.046
ribonucleoside triphosphate catabolic process GO:0009203 391 0.046
digestive system development GO:0055123 75 0.046
mesenchymal cell development GO:0014031 50 0.045
regulation of protein polymerization GO:0032271 63 0.045
positive regulation of rac gtpase activity GO:0032855 31 0.044
divalent inorganic cation homeostasis GO:0072507 136 0.044
positive regulation of ras gtpase activity GO:0032320 117 0.044
regulation of protein import into nucleus GO:0042306 78 0.044
collagen metabolic process GO:0032963 28 0.043
locomotory behavior GO:0007626 1 0.043
negative regulation of anoikis GO:2000811 15 0.043
negative regulation of cell death GO:0060548 345 0.042
response to lipopolysaccharide GO:0032496 70 0.042
regulation of chromosome segregation GO:0051983 44 0.042
salivary gland development GO:0007431 5 0.041
formation of primary germ layer GO:0001704 42 0.041
spermatid differentiation GO:0048515 4 0.040
response to abiotic stimulus GO:0009628 336 0.040
interaction with host GO:0051701 42 0.040
divalent inorganic cation transport GO:0072511 158 0.040
lipid localization GO:0010876 106 0.039
reproductive structure development GO:0048608 55 0.039
oogenesis GO:0048477 2 0.039
hemopoiesis GO:0030097 180 0.039
regulation of cardioblast differentiation GO:0051890 4 0.039
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.039
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.039
single organismal cell cell adhesion GO:0016337 148 0.039
nuclear division GO:0000280 128 0.038
positive regulation of rho gtpase activity GO:0032321 56 0.038
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 38 0.038
protein targeting to nucleus GO:0044744 104 0.038
associative learning GO:0008306 1 0.038
peripheral nervous system development GO:0007422 2 0.038
cellular amino acid metabolic process GO:0006520 116 0.038
wnt signaling pathway GO:0016055 156 0.037
regulation of cytoplasmic transport GO:1903649 149 0.037
regulation of rho gtpase activity GO:0032319 66 0.037
vasculature development GO:0001944 181 0.037
cell division GO:0051301 168 0.037
mitochondrion organization GO:0007005 156 0.037
cartilage development GO:0051216 31 0.036
endothelium development GO:0003158 33 0.036
regulation of calcium ion transport GO:0051924 79 0.036
centrosome organization GO:0051297 58 0.036
regulation of ion transport GO:0043269 189 0.036
lens development in camera type eye GO:0002088 2 0.036
positive regulation of phosphorylation GO:0042327 394 0.036
regulation of cell substrate adhesion GO:0010810 68 0.036
axon development GO:0061564 34 0.036
Fly
divalent metal ion transport GO:0070838 152 0.036
positive regulation of establishment of protein localization to plasma membrane GO:0090004 18 0.036
positive regulation of cholesterol storage GO:0010886 4 0.035
regulation of cellular response to growth factor stimulus GO:0090287 76 0.035
cellular protein catabolic process GO:0044257 261 0.035
immune effector process GO:0002252 159 0.035
anion transmembrane transport GO:0098656 76 0.035
regulation of ras gtpase activity GO:0032318 128 0.034
cellular response to hypoxia GO:0071456 51 0.034
cellular response to oxygen containing compound GO:1901701 276 0.034
spindle organization GO:0007051 53 0.034
protein import into nucleus GO:0006606 104 0.034
epithelial cell migration GO:0010631 119 0.034
odontogenesis GO:0042476 25 0.033
response to oxygen containing compound GO:1901700 369 0.033
action potential GO:0001508 34 0.033
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.033
Fly
cardiac muscle tissue development GO:0048738 39 0.033
response to wounding GO:0009611 168 0.033
Human
cellular ion homeostasis GO:0006873 168 0.033
axon guidance GO:0007411 12 0.033
Fly
apoptotic signaling pathway GO:0097190 268 0.033
regulation of transferase activity GO:0051338 355 0.033
mitotic nuclear division GO:0007067 119 0.033
negative regulation of cell differentiation GO:0045596 171 0.033
cell fate commitment GO:0045165 27 0.033
Fly
lipid transport GO:0006869 90 0.032
amine metabolic process GO:0009308 44 0.032
nucleotide catabolic process GO:0009166 408 0.032
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.032
regulation of immune response GO:0050776 201 0.032
axonogenesis GO:0007409 31 0.032
Fly
ubiquitin dependent protein catabolic process GO:0006511 206 0.032
innate immune response GO:0045087 178 0.032
actin mediated cell contraction GO:0070252 12 0.032
regulation of protein catabolic process GO:0042176 155 0.032
angiogenesis GO:0001525 147 0.032
response to other organism GO:0051707 261 0.031
regulation of ion homeostasis GO:2000021 73 0.031
neuronal action potential GO:0019228 9 0.031
chromosome segregation GO:0007059 114 0.031
posttranscriptional regulation of gene expression GO:0010608 213 0.031
neuromuscular junction development GO:0007528 3 0.031
protein localization to organelle GO:0033365 280 0.031
skeletal muscle organ development GO:0060538 26 0.031
muscle tissue development GO:0060537 62 0.031
response to lipid GO:0033993 206 0.031
nail development GO:0035878 3 0.031
cellular potassium ion transport GO:0071804 60 0.030
tissue morphogenesis GO:0048729 96 0.030
Fly
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.030
cation homeostasis GO:0055080 189 0.030
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.030
modification dependent macromolecule catabolic process GO:0043632 212 0.030
positive regulation of protein localization to nucleus GO:1900182 48 0.030
neuron projection guidance GO:0097485 12 0.030
Fly
positive regulation of intracellular protein transport GO:0090316 76 0.029
nitrogen compound transport GO:0071705 191 0.029
regulation of axon guidance GO:1902667 3 0.029
kidney development GO:0001822 53 0.029
response to organonitrogen compound GO:0010243 156 0.029
multicellular organismal signaling GO:0035637 34 0.029
modification dependent protein catabolic process GO:0019941 209 0.029
receptor metabolic process GO:0043112 81 0.029
nucleotide biosynthetic process GO:0009165 109 0.028
regulation of cardiac muscle cell membrane potential GO:0086036 1 0.028
rac protein signal transduction GO:0016601 12 0.028
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.028
epithelial to mesenchymal transition GO:0001837 48 0.028
protein import GO:0017038 130 0.028
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.028
regulation of protein targeting GO:1903533 91 0.028
nuclear import GO:0051170 106 0.028
endosomal transport GO:0016197 129 0.027
protein oligomerization GO:0051259 173 0.027
cellular metal ion homeostasis GO:0006875 146 0.027
defense response GO:0006952 315 0.027
striated muscle myosin thick filament assembly GO:0071688 2 0.027
neuroblast proliferation GO:0007405 4 0.027
regulation of inflammatory response GO:0050727 46 0.027
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.027
actin crosslink formation GO:0051764 1 0.026
adult behavior GO:0030534 18 0.026
sex differentiation GO:0007548 45 0.026
response to hormone GO:0009725 175 0.026
positive regulation of odontogenesis GO:0042482 3 0.026
neuron projection regeneration GO:0031102 1 0.026
myeloid leukocyte differentiation GO:0002573 60 0.026
response to oxygen levels GO:0070482 100 0.026
renal system process GO:0003014 25 0.025
regulation of anatomical structure size GO:0090066 101 0.025
Fly
negative regulation of lipid transport GO:0032369 18 0.025
osteoblast differentiation GO:0001649 92 0.025
positive regulation of cell migration GO:0030335 172 0.025
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.025
inflammatory response GO:0006954 79 0.025
positive regulation of protein transport GO:0051222 135 0.025
organelle localization GO:0051640 84 0.025
cellular response to external stimulus GO:0071496 111 0.025
positive regulation of cellular component biogenesis GO:0044089 158 0.025
Fly
negative regulation of phosphorus metabolic process GO:0010563 267 0.025
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.024
regulation of response to wounding GO:1903034 101 0.024
regulation of mitotic cell cycle GO:0007346 189 0.024
regulation of chemotaxis GO:0050920 74 0.024
odontogenesis of dentin containing tooth GO:0042475 10 0.024
myeloid cell differentiation GO:0030099 117 0.024
morphogenesis of a branching epithelium GO:0061138 20 0.024
Fly
negative regulation of apoptotic process GO:0043066 316 0.024
regulation of cellular component movement GO:0051270 334 0.024
negative regulation of cellular protein metabolic process GO:0032269 353 0.023
ribose phosphate biosynthetic process GO:0046390 82 0.023
adherens junction assembly GO:0034333 34 0.023
embryo development ending in birth or egg hatching GO:0009792 34 0.023
immune system development GO:0002520 195 0.023
nuclear migration GO:0007097 1 0.023
positive regulation of gtp catabolic process GO:0033126 166 0.023
cellular protein complex assembly GO:0043623 188 0.023
anterior posterior axis specification GO:0009948 2 0.022
atp catabolic process GO:0006200 157 0.022
t cell activation GO:0042110 99 0.022

PLEC disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.556
muscle tissue disease DOID:66 113 0.556
myopathy DOID:423 104 0.556
muscular disease DOID:0080000 114 0.556
cardiovascular system disease DOID:1287 106 0.320
urinary system disease DOID:18 40 0.244
muscular dystrophy DOID:9884 51 0.136
kidney disease DOID:557 36 0.124
emery dreifuss muscular dystrophy DOID:11726 6 0.085
central nervous system disease DOID:331 186 0.037
nervous system disease DOID:863 431 0.037
cardiomyopathy DOID:0050700 50 0.033
intrinsic cardiomyopathy DOID:0060036 50 0.033
heart disease DOID:114 68 0.033
limb girdle muscular dystrophy DOID:11724 25 0.031
immune system disease DOID:2914 155 0.030
integumentary system disease DOID:16 43 0.026
skin disease DOID:37 33 0.026
lipodystrophy DOID:811 7 0.026
sensory system disease DOID:0050155 203 0.025
auditory system disease DOID:2742 53 0.025
neuromuscular disease DOID:440 38 0.024
neuropathy DOID:870 52 0.024
brain disease DOID:936 73 0.024
electroclinical syndrome DOID:0050701 32 0.024
epilepsy syndrome DOID:1826 41 0.024
neonatal period electroclinical syndrome DOID:0050702 19 0.022