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Process View

Homo sapiens

10 genes annotated in human

Multi-species View

mesodermal cell differentiation

GO:0048333

The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "mesodermal cell differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "mesodermal cell differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	1.000
FHL2	four and a half LIM domains 2	1.000
FGF1	fibroblast growth factor 1 (acidic)	0.989
BMPR1A	bone morphogenetic protein receptor, type IA	0.984	Mouse
FN1	fibronectin 1	0.942
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.936
BMP2	bone morphogenetic protein 2	0.922	Human Zebrafish
PBX1	pre-B-cell leukemia homeobox 1	0.904	Worm
PDIA3	protein disulfide isomerase family A, member 3	0.885
SMAD3	SMAD family member 3	0.814
MEIS1	Meis homeobox 1	0.762	Worm
PXN	paxillin	0.678
ITGA6	integrin, alpha 6	0.620	Human
TLN1	talin 1	0.597
JAG1	jagged 1	0.569
SETD8	SET domain containing (lysine methyltransferase) 8	0.499
ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	0.401	Human
PTPRC	protein tyrosine phosphatase, receptor type, C	0.333
FOXD3	forkhead box D3	0.311
GATA2	GATA binding protein 2	0.304
ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)	0.290	Human
FGFR2	fibroblast growth factor receptor 2	0.269	Rat Fly
FLNA	filamin A, alpha	0.266
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.235
ENG	endoglin	0.199
ZFX	zinc finger protein, X-linked	0.186
LRP6	low density lipoprotein receptor-related protein 6	0.179
ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	0.170
RUNX1	runt-related transcription factor 1	0.164
CD63	CD63 molecule	0.138
AR	androgen receptor	0.130
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.126
SMAD4	SMAD family member 4	0.124
FSTL1	follistatin-like 1	0.123
CYTH1	cytohesin 1	0.112
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.100
PLEC	plectin	0.097
CTGF	connective tissue growth factor	0.095
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.092
SMAD7	SMAD family member 7	0.091
SOX2	SRY (sex determining region Y)-box 2	0.090
NOTCH3	notch 3	0.089
ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	0.088
SMAD2	SMAD family member 2	0.083
RANBP9	RAN binding protein 9	0.081
EPS8	epidermal growth factor receptor pathway substrate 8	0.075
FZD1	frizzled homolog 1 (Drosophila)	0.074
RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	0.069
THBS1	thrombospondin 1	0.065
MEIS2	Meis homeobox 2	0.058	Worm
FGFR1	fibroblast growth factor receptor 1	0.057	Mouse Fly
ITGB4	integrin, beta 4	0.056
FHL3	four and a half LIM domains 3	0.045
FGF2	fibroblast growth factor 2 (basic)	0.043
FGF10	fibroblast growth factor 10	0.042
PRMT6	protein arginine methyltransferase 6	0.041
FOXF2	forkhead box F2	0.040
GATA1	GATA binding protein 1 (globin transcription factor 1)	0.039
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.038
CD9	CD9 molecule	0.038
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.036
ZFYVE9	zinc finger, FYVE domain containing 9	0.036
SELPLG	selectin P ligand	0.034
HOXA10	homeobox A10	0.034
ITGB5	integrin, beta 5	0.031	Human
HSPG2	heparan sulfate proteoglycan 2	0.029
BBS1	Bardet-Biedl syndrome 1	0.029
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.027
TCF4	transcription factor 4	0.026
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.026
SMAD9	SMAD family member 9	0.025
FZD8	frizzled homolog 8 (Drosophila)	0.025
ATXN1	ataxin 1	0.024
TENC1	tensin like C1 domain containing phosphatase (tensin 2)	0.022
HOXA9	homeobox A9	0.021
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.020
CREBBP	CREB binding protein	0.020
TCF12	transcription factor 12	0.019
HIC1	hypermethylated in cancer 1	0.019
SMAD6	SMAD family member 6	0.018
NFIB	nuclear factor I/B	0.017
ADAM9	ADAM metallopeptidase domain 9	0.017
KRT8	keratin 8	0.016
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.016	Human
ANGPTL4	angiopoietin-like 4	0.016
FOXC1	forkhead box C1	0.015
LAMC2	laminin, gamma 2	0.015
ACVR1	activin A receptor, type I	0.014
BMP4	bone morphogenetic protein 4	0.013
COL17A1	collagen, type XVII, alpha 1	0.013
APP	amyloid beta (A4) precursor protein	0.013
FBLN1	fibulin 1	0.013
ZMYND11	zinc finger, MYND-type containing 11	0.012
LAMC1	laminin, gamma 1 (formerly LAMB2)	0.012
NOTCH2	notch 2	0.012
FLNB	filamin B, beta	0.012
FGFR3	fibroblast growth factor receptor 3	0.012	Fly
QKI	quaking homolog, KH domain RNA binding (mouse)	0.012
USP9X	ubiquitin specific peptidase 9, X-linked	0.011
VCAM1	vascular cell adhesion molecule 1	0.010
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.010
ANXA5	annexin A5	0.010
ITGB7	integrin, beta 7	0.010	Human
MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4	0.010
TGFB2	transforming growth factor, beta 2	0.010
DST	dystonin	0.010