|
|
activation of transmembrane receptor protein tyrosine kinase activity
|
GO:0007171 |
4 |
0.965
|
|
|
|
platelet derived growth factor receptor beta signaling pathway
|
GO:0035791 |
4 |
0.944
|
|
|
|
regulation of tyrosine phosphorylation of stat1 protein
|
GO:0042510 |
11 |
0.915
|
|
|
|
regulation of hepatocyte growth factor receptor signaling pathway
|
GO:1902202 |
4 |
0.901
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.878
|
|
|
|
regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042516 |
18 |
0.847
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.844
|
|
|
|
receptor internalization
|
GO:0031623 |
43 |
0.843
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.830
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.825
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.810
|
Human |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.807
|
Human |
|
|
angiogenesis involved in wound healing
|
GO:0060055 |
4 |
0.803
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.801
|
|
|
|
cellular response to macrophage colony stimulating factor stimulus
|
GO:0036006 |
4 |
0.776
|
|
|
|
peptidyl tyrosine dephosphorylation
|
GO:0035335 |
36 |
0.749
|
Human Fly |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.733
|
Human |
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.726
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.706
|
|
|
|
tyrosine phosphorylation of stat5 protein
|
GO:0042506 |
13 |
0.692
|
|
|
|
regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042522 |
12 |
0.691
|
|
|
|
branched chain amino acid metabolic process
|
GO:0009081 |
4 |
0.671
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.669
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.656
|
|
|
|
taurine metabolic process
|
GO:0019530 |
1 |
0.644
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.640
|
|
|
|
negative regulation of wound healing
|
GO:0061045 |
25 |
0.626
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.625
|
|
|
|
tyrosine phosphorylation of stat3 protein
|
GO:0042503 |
20 |
0.606
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.602
|
|
|
|
regulation of interleukin 6 mediated signaling pathway
|
GO:0070103 |
3 |
0.582
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.573
|
Human |
|
|
tyrosine phosphorylation of stat protein
|
GO:0007260 |
33 |
0.573
|
|
|
|
positive regulation of focal adhesion assembly
|
GO:0051894 |
11 |
0.565
|
Human |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.547
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.529
|
|
|
|
protein dephosphorylation
|
GO:0006470 |
81 |
0.522
|
Human Fly |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.522
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.514
|
|
|
|
regulation of adherens junction organization
|
GO:1903391 |
21 |
0.513
|
Human |
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.509
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.500
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.489
|
Human |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.484
|
|
|
|
calcium mediated signaling using intracellular calcium source
|
GO:0035584 |
7 |
0.483
|
|
|
|
hepatocyte growth factor receptor signaling pathway
|
GO:0048012 |
8 |
0.482
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.481
|
Human |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.477
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.477
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.474
|
|
|
|
regulation of glomerulus development
|
GO:0090192 |
3 |
0.472
|
|
|
|
vascular wound healing
|
GO:0061042 |
4 |
0.470
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.469
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.467
|
|
|
|
regulation of chemotaxis
|
GO:0050920 |
74 |
0.465
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.462
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.462
|
Human |
|
|
tyrosine phosphorylation of stat1 protein
|
GO:0042508 |
11 |
0.460
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.447
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.442
|
|
|
|
positive regulation of cell junction assembly
|
GO:1901890 |
11 |
0.441
|
Human |
|
|
negative regulation of jak stat cascade
|
GO:0046426 |
4 |
0.440
|
|
|
|
response to macrophage colony stimulating factor
|
GO:0036005 |
4 |
0.439
|
|
|
|
regulation of vascular endothelial growth factor receptor signaling pathway
|
GO:0030947 |
9 |
0.428
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.426
|
|
|
|
cartilage development involved in endochondral bone morphogenesis
|
GO:0060351 |
2 |
0.424
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.418
|
Human |
|
|
adherens junction assembly
|
GO:0034333 |
34 |
0.409
|
Human |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.406
|
Human |
|
|
patterning of blood vessels
|
GO:0001569 |
2 |
0.403
|
|
|
|
regulation of vascular wound healing
|
GO:0061043 |
2 |
0.401
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.391
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.388
|
|
|
|
positive regulation of histone deacetylase activity
|
GO:1901727 |
3 |
0.382
|
|
|
|
positive regulation of adherens junction organization
|
GO:1903393 |
12 |
0.381
|
Human |
|
|
negative regulation of response to wounding
|
GO:1903035 |
47 |
0.380
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.379
|
|
|
|
regulation of tyrosine phosphorylation of stat protein
|
GO:0042509 |
30 |
0.377
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.376
|
|
|
|
sprouting angiogenesis
|
GO:0002040 |
29 |
0.372
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.367
|
Human |
|
|
response to peptide
|
GO:1901652 |
65 |
0.364
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.363
|
Human |
|
|
cellular lactam metabolic process
|
GO:0072338 |
1 |
0.356
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.354
|
|
|
|
negative regulation of cytokine mediated signaling pathway
|
GO:0001960 |
22 |
0.351
|
|
|
|
platelet derived growth factor receptor signaling pathway
|
GO:0048008 |
14 |
0.340
|
Human |
|
|
positive regulation of peptidyl tyrosine autophosphorylation
|
GO:1900086 |
1 |
0.335
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.332
|
|
|
|
positive regulation of hematopoietic progenitor cell differentiation
|
GO:1901534 |
5 |
0.328
|
|
|
|
positive regulation of phospholipase c activity
|
GO:0010863 |
13 |
0.326
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.322
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.321
|
|
|
|
negative regulation of hemostasis
|
GO:1900047 |
22 |
0.320
|
|
|
|
cell substrate adherens junction assembly
|
GO:0007045 |
30 |
0.319
|
Human |
|
|
tissue migration
|
GO:0090130 |
119 |
0.317
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.316
|
|
|
|
negative regulation of phosphatidylinositol biosynthetic process
|
GO:0010512 |
2 |
0.316
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.314
|
Human |
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
84 |
0.314
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.307
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.306
|
Human |
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.306
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.304
|
Mouse |
|
|
taxis
|
GO:0042330 |
157 |
0.302
|
Human Fly |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.293
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.293
|
|
|
|
positive regulation of vascular wound healing
|
GO:0035470 |
1 |
0.292
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.292
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.290
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.288
|
|
|
|
vegf activated platelet derived growth factor receptor signaling pathway
|
GO:0038086 |
3 |
0.288
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.286
|
Human |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.282
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.280
|
Mouse |
|
|
cellular response to insulin stimulus
|
GO:0032869 |
41 |
0.279
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.279
|
Human |
|
|
cation transport
|
GO:0006812 |
331 |
0.278
|
|
|
|
multicellular organismal metabolic process
|
GO:0044236 |
34 |
0.276
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.267
|
|
|
|
vascular endothelial growth factor receptor 1 signaling pathway
|
GO:0036323 |
1 |
0.262
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.259
|
Mouse |
|
|
blood circulation
|
GO:0008015 |
113 |
0.259
|
Human |
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.254
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.251
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.250
|
|
|
|
glycerolipid biosynthetic process
|
GO:0045017 |
51 |
0.247
|
|
|
|
negative regulation of response to cytokine stimulus
|
GO:0060761 |
25 |
0.246
|
|
|
|
regulation of blood coagulation
|
GO:0030193 |
42 |
0.246
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.246
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.245
|
|
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.244
|
|
|
|
positive regulation of glomerular mesangial cell proliferation
|
GO:0072126 |
1 |
0.243
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.243
|
|
|
|
regulation of cell junction assembly
|
GO:1901888 |
29 |
0.241
|
Human |
|
|
regulation of endothelial cell differentiation
|
GO:0045601 |
4 |
0.241
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.240
|
Human |
|
|
positive regulation of transcription from rna polymerase ii promoter in response to hypoxia
|
GO:0061419 |
2 |
0.237
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.235
|
Mouse |
|
|
positive regulation of tyrosine phosphorylation of stat5 protein
|
GO:0042523 |
11 |
0.233
|
|
|
|
cell junction maintenance
|
GO:0034331 |
4 |
0.232
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.232
|
Human |
|
|
positive regulation of mast cell chemotaxis
|
GO:0060754 |
4 |
0.231
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.231
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.230
|
|
|
|
oxaloacetate metabolic process
|
GO:0006107 |
1 |
0.228
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.228
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.226
|
Fly |
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.226
|
Human |
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.225
|
|
|
|
positive regulation of phospholipase activity
|
GO:0010518 |
22 |
0.223
|
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
35 |
0.221
|
|
|
|
positive regulation of p38mapk cascade
|
GO:1900745 |
8 |
0.219
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.219
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.218
|
|
|
|
succinate metabolic process
|
GO:0006105 |
1 |
0.215
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.212
|
Human |
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.208
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.208
|
|
|
|
cellular response to peptide hormone stimulus
|
GO:0071375 |
56 |
0.208
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.206
|
Human |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.206
|
Human |
|
|
positive regulation of cell proliferation by vegf activated platelet derived growth factor receptor signaling pathway
|
GO:0038091 |
3 |
0.203
|
|
|
|
regulation of glomerular mesangial cell proliferation
|
GO:0072124 |
3 |
0.203
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.199
|
|
|
|
response to insulin
|
GO:0032868 |
45 |
0.197
|
|
|
|
negative regulation of type i interferon mediated signaling pathway
|
GO:0060339 |
4 |
0.195
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.195
|
Mouse |
|
|
regulation of muscle system process
|
GO:0090257 |
53 |
0.193
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.190
|
Human |
|
|
actin cytoskeleton reorganization
|
GO:0031532 |
37 |
0.190
|
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.188
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.188
|
|
|
|
positive regulation of cytosolic calcium ion concentration
|
GO:0007204 |
82 |
0.187
|
|
|
|
myeloid leukocyte migration
|
GO:0097529 |
62 |
0.183
|
Human |
|
|
positive regulation of lipase activity
|
GO:0060193 |
28 |
0.183
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.180
|
|
|
|
platelet derived growth factor receptor alpha signaling pathway
|
GO:0035790 |
1 |
0.180
|
|
|
|
regulation of hemostasis
|
GO:1900046 |
42 |
0.178
|
|
|
|
basophil chemotaxis
|
GO:0002575 |
1 |
0.178
|
|
|
|
negative regulation of endothelial cell apoptotic process
|
GO:2000352 |
16 |
0.177
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.177
|
|
|
|
focal adhesion assembly
|
GO:0048041 |
30 |
0.174
|
Human |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.173
|
Human |
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.172
|
Human |
|
|
blood coagulation
|
GO:0007596 |
76 |
0.172
|
|
|
|
regulation of receptor internalization
|
GO:0002090 |
15 |
0.170
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
57 |
0.169
|
|
|
|
response to peptide hormone
|
GO:0043434 |
61 |
0.165
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.163
|
Human |
|
|
positive regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042517 |
16 |
0.162
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.161
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.160
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.159
|
Human |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.158
|
Human |
|
|
response to stem cell factor
|
GO:0036215 |
1 |
0.158
|
|
|
|
cell proliferation involved in kidney development
|
GO:0072111 |
3 |
0.157
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.157
|
Human |
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.156
|
Human |
|
|
cytokine production
|
GO:0001816 |
247 |
0.156
|
|
|
|
regulation of endothelial cell apoptotic process
|
GO:2000351 |
24 |
0.155
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.153
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.153
|
|
|
|
citrate metabolic process
|
GO:0006101 |
2 |
0.152
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.152
|
Human |
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.151
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.151
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.150
|
|
|
|
system process
|
GO:0003008 |
349 |
0.148
|
Human Fly |
|
|
negative regulation of tyrosine phosphorylation of stat3 protein
|
GO:0042518 |
2 |
0.148
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.148
|
|
|
|
regulation of cell proliferation involved in kidney development
|
GO:1901722 |
3 |
0.147
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.146
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.146
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.146
|
|
|
|
interleukin 2 mediated signaling pathway
|
GO:0038110 |
3 |
0.144
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.144
|
|
|
|
lung alveolus development
|
GO:0048286 |
4 |
0.144
|
|
|
|
2 oxoglutarate metabolic process
|
GO:0006103 |
4 |
0.144
|
|
|
|
tricarboxylic acid metabolic process
|
GO:0072350 |
4 |
0.142
|
|
|
|
positive regulation of secretion by cell
|
GO:1903532 |
108 |
0.142
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.142
|
Mouse |
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.142
|
|
|
|
positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway
|
GO:0038033 |
4 |
0.141
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.140
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.140
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.139
|
|
|
|
regulation of type i interferon mediated signaling pathway
|
GO:0060338 |
9 |
0.137
|
|
|
|
vascular process in circulatory system
|
GO:0003018 |
29 |
0.137
|
Human |
|
|
positive regulation of protein tyrosine kinase activity
|
GO:0061098 |
24 |
0.136
|
|
|
|
platelet activation
|
GO:0030168 |
44 |
0.135
|
|
|
|
regulation of vascular endothelial growth factor production
|
GO:0010574 |
13 |
0.134
|
|
|
|
exocytosis
|
GO:0006887 |
71 |
0.134
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.134
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.134
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.131
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.131
|
|
|
|
positive regulation of nitric oxide synthase biosynthetic process
|
GO:0051770 |
3 |
0.129
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.129
|
|
|
|
activation of janus kinase activity
|
GO:0042976 |
7 |
0.128
|
|
|
|
regulation of muscle contraction
|
GO:0006937 |
45 |
0.127
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.127
|
Human |
|
|
positive regulation of receptor internalization
|
GO:0002092 |
12 |
0.125
|
|
|
|
regulation of peptidyl tyrosine autophosphorylation
|
GO:1900084 |
1 |
0.124
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.123
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.123
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.123
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.123
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.122
|
Human |
|
|
coagulation
|
GO:0050817 |
78 |
0.122
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
59 |
0.121
|
|
|
|
regulation of chemokine production
|
GO:0032642 |
31 |
0.121
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.120
|
Human |
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.120
|
Mouse |
|
|
endocytosis
|
GO:0006897 |
159 |
0.119
|
|
|
|
cellular modified amino acid metabolic process
|
GO:0006575 |
64 |
0.119
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.118
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.118
|
|
|
|
smooth muscle contraction
|
GO:0006939 |
14 |
0.117
|
|
|
|
activation of jak2 kinase activity
|
GO:0042977 |
5 |
0.117
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.117
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.117
|
Human |
|
|
cell migration involved in metanephros development
|
GO:0035788 |
2 |
0.116
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.116
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.116
|
|
|
|
regulation of heart contraction
|
GO:0008016 |
50 |
0.115
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.115
|
Human |
|
|
positive regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway
|
GO:0035793 |
2 |
0.114
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.111
|
|
|
|
cyclic nucleotide metabolic process
|
GO:0009187 |
82 |
0.110
|
|
|
|
negative regulation of platelet activation
|
GO:0010544 |
7 |
0.109
|
|
|
|
metanephric mesenchymal cell migration
|
GO:0035789 |
2 |
0.109
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.109
|
|
|
|
regulation of phosphatidylinositol biosynthetic process
|
GO:0010511 |
5 |
0.108
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.107
|
Human |
|
|
regulation of vascular permeability
|
GO:0043114 |
11 |
0.107
|
Human |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.106
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.106
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.106
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.105
|
|
|
|
regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway
|
GO:1900238 |
2 |
0.105
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.105
|
|
|
|
regulation of smooth muscle cell proliferation
|
GO:0048660 |
28 |
0.105
|
|
|
|
creatinine metabolic process
|
GO:0046449 |
1 |
0.104
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.104
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.104
|
Human |
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.103
|
|
|
|
response to estradiol
|
GO:0032355 |
23 |
0.103
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.103
|
|
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.102
|
|
|
|
humoral immune response
|
GO:0006959 |
49 |
0.102
|
|
|
|
regulation of branching involved in ureteric bud morphogenesis
|
GO:0090189 |
3 |
0.102
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.101
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.101
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.100
|
|
|
|
alpha amino acid metabolic process
|
GO:1901605 |
72 |
0.100
|
|
|
|
negative regulation of macrophage differentiation
|
GO:0045650 |
2 |
0.099
|
|
|
|
regulation of behavior
|
GO:0050795 |
82 |
0.099
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.099
|
Human |
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.099
|
|
|
|
regulation of hematopoietic progenitor cell differentiation
|
GO:1901532 |
24 |
0.097
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.097
|
|
|
|
phosphatidylinositol metabolic process
|
GO:0046488 |
53 |
0.096
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
139 |
0.096
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.096
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.096
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.096
|
|
|
|
fatty acid metabolic process
|
GO:0006631 |
115 |
0.096
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
63 |
0.095
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.095
|
Human |
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.095
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.094
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.094
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.094
|
|
|
|
mitotic spindle elongation
|
GO:0000022 |
4 |
0.094
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.093
|
Human |
|
|
cell substrate junction assembly
|
GO:0007044 |
35 |
0.093
|
Human |
|
|
heart contraction
|
GO:0060047 |
62 |
0.093
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.092
|
Human |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.092
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.091
|
Human Fly |
|
|
regulation of metanephric mesenchymal cell migration
|
GO:2000589 |
2 |
0.091
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.088
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.088
|
|
|
|
positive regulation of dna replication
|
GO:0045740 |
35 |
0.088
|
|
|
|
negative regulation of blood coagulation
|
GO:0030195 |
22 |
0.088
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.088
|
|
|
|
glomerular mesangial cell proliferation
|
GO:0072110 |
3 |
0.087
|
|
|
|
positive regulation of metanephric mesenchymal cell migration
|
GO:2000591 |
2 |
0.087
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.087
|
Human |
|
|
protein maturation
|
GO:0051604 |
233 |
0.086
|
|
|
|
negative regulation of coagulation
|
GO:0050819 |
24 |
0.086
|
|
|
|
regulation of focal adhesion assembly
|
GO:0051893 |
20 |
0.085
|
Human |
|
|
blood vessel maturation
|
GO:0001955 |
1 |
0.085
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.085
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.085
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.084
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
27 |
0.084
|
|
|
|
negative regulation of lipid metabolic process
|
GO:0045833 |
38 |
0.083
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.082
|
|
|
|
endothelial cell apoptotic process
|
GO:0072577 |
26 |
0.082
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.081
|
|
|
|
mucopolysaccharide metabolic process
|
GO:1903510 |
27 |
0.081
|
|
|
|
response to corticosteroid
|
GO:0031960 |
15 |
0.080
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.080
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.080
|
Human |
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.079
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.079
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.079
|
|
|
|
response to food
|
GO:0032094 |
1 |
0.079
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.079
|
|
|
|
lymph vessel morphogenesis
|
GO:0036303 |
7 |
0.079
|
|
|
|
leukocyte migration
|
GO:0050900 |
107 |
0.079
|
Human |
|
|
platelet aggregation
|
GO:0070527 |
32 |
0.078
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.078
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.078
|
Human |
|
|
development of primary male sexual characteristics
|
GO:0046546 |
23 |
0.077
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.077
|
|
|
|
positive regulation of hyaluronan biosynthetic process
|
GO:1900127 |
3 |
0.076
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.076
|
Human |
|
|
type i interferon signaling pathway
|
GO:0060337 |
11 |
0.076
|
|
|
|
mast cell chemotaxis
|
GO:0002551 |
5 |
0.074
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.074
|
Fly |
|
|
regulation of transmembrane transporter activity
|
GO:0022898 |
74 |
0.073
|
|
|
|
regulation of histone deacetylase activity
|
GO:1901725 |
3 |
0.073
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.073
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.073
|
|
|
|
spindle elongation
|
GO:0051231 |
4 |
0.072
|
|
|
|
mast cell cytokine production
|
GO:0032762 |
1 |
0.072
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.072
|
|
|
|
positive regulation of metanephros development
|
GO:0072216 |
3 |
0.072
|
|
|
|
positive regulation of lipid metabolic process
|
GO:0045834 |
50 |
0.070
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.069
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.069
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.069
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.069
|
Human |
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
20 |
0.069
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.068
|
|
|
|
protein kinase c signaling
|
GO:0070528 |
17 |
0.068
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.067
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.067
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.067
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.067
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.067
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.067
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.067
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.066
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.066
|
Fly |
|
|
kidney vasculature development
|
GO:0061440 |
7 |
0.066
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.065
|
|
|
|
cellular response to interleukin 6
|
GO:0071354 |
14 |
0.064
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.064
|
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.064
|
|
|
|
regulation of axon guidance
|
GO:1902667 |
3 |
0.064
|
|
|
|
activation of mapkk activity
|
GO:0000186 |
18 |
0.064
|
|
|
|
chemokine production
|
GO:0032602 |
32 |
0.064
|
|
|
|
vascular endothelial growth factor signaling pathway
|
GO:0038084 |
15 |
0.064
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
19 |
0.063
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.063
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
60 |
0.062
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.062
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.062
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.062
|
|
|
|
regulation of protein kinase c signaling
|
GO:0090036 |
8 |
0.062
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.061
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.060
|
|
|
|
positive regulation of leukocyte chemotaxis
|
GO:0002690 |
38 |
0.060
|
|
|
|
negative regulation of interleukin 6 mediated signaling pathway
|
GO:0070104 |
2 |
0.059
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.059
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.059
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.059
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.059
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.058
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.058
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.058
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.058
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.058
|
Fly |
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.058
|
|
|
|
smooth muscle cell proliferation
|
GO:0048659 |
28 |
0.057
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.057
|
|
|
|
regulation of lipid kinase activity
|
GO:0043550 |
19 |
0.057
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.057
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.057
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.056
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.056
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.055
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.055
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.055
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.055
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.055
|
|
|
|
positive regulation of wound healing
|
GO:0090303 |
20 |
0.055
|
|
|
|
lymphangiogenesis
|
GO:0001946 |
7 |
0.055
|
|
|
|
regulation of wound healing
|
GO:0061041 |
56 |
0.055
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.054
|
|
|
|
cell migration involved in kidney development
|
GO:0035787 |
2 |
0.054
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.054
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.054
|
|
|
|
monocyte differentiation
|
GO:0030224 |
15 |
0.054
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.054
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
46 |
0.053
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.053
|
|
|
|
male sex differentiation
|
GO:0046661 |
25 |
0.053
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.053
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.053
|
|
|
|
positive regulation of behavior
|
GO:0048520 |
60 |
0.052
|
|
|
|
cellular response to unfolded protein
|
GO:0034620 |
16 |
0.052
|
|
|
|
negative chemotaxis
|
GO:0050919 |
11 |
0.052
|
|
|
|
growth hormone receptor signaling pathway
|
GO:0060396 |
10 |
0.052
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.052
|
|
|
|
positive regulation of endothelial cell proliferation
|
GO:0001938 |
37 |
0.052
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.051
|
Human |
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.051
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
20 |
0.051
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.051
|
|
|
|
endothelium development
|
GO:0003158 |
33 |
0.051
|
|
|
|
negative regulation of t cell receptor signaling pathway
|
GO:0050860 |
4 |
0.050
|
Human |
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.050
|
Human |
|
|
homotypic cell cell adhesion
|
GO:0034109 |
47 |
0.049
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.049
|
|
|
|
cellular response to interleukin 15
|
GO:0071350 |
6 |
0.049
|
|
|
|
positive regulation of lipid kinase activity
|
GO:0090218 |
13 |
0.049
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.049
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.049
|
Fly |
|
|
response to cycloheximide
|
GO:0046898 |
1 |
0.049
|
|
|
|
regulation of mast cell chemotaxis
|
GO:0060753 |
4 |
0.049
|
|
|
|
response to interleukin 1
|
GO:0070555 |
47 |
0.048
|
|
|
|
cellular amide metabolic process
|
GO:0043603 |
69 |
0.048
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.048
|
|
|
|
negative regulation of cell activation
|
GO:0050866 |
33 |
0.048
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.048
|
|
|
|
positive regulation of ion transmembrane transport
|
GO:0034767 |
40 |
0.048
|
|
|
|
growth
|
GO:0040007 |
202 |
0.048
|
Human |
|
|
regulation of axon extension involved in axon guidance
|
GO:0048841 |
2 |
0.047
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.047
|
|
|
|
positive regulation of cell matrix adhesion
|
GO:0001954 |
23 |
0.047
|
Human |
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
2 |
0.046
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.046
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.046
|
|
|
|
regulation of leukocyte chemotaxis
|
GO:0002688 |
46 |
0.046
|
|
|
|
response to growth hormone
|
GO:0060416 |
11 |
0.046
|
|
|
|
kidney epithelium development
|
GO:0072073 |
25 |
0.045
|
|
|
|
kit signaling pathway
|
GO:0038109 |
1 |
0.045
|
|
|
|
regulation of blood vessel endothelial cell migration
|
GO:0043535 |
30 |
0.045
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.045
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.044
|
Fly |
|
|
skeletal system morphogenesis
|
GO:0048705 |
24 |
0.044
|
|
|
|
cellular response to topologically incorrect protein
|
GO:0035967 |
19 |
0.044
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.044
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.044
|
|
|
|
regulation of vasculogenesis
|
GO:2001212 |
3 |
0.044
|
|
