IMP

Process View

Homo sapiens

1 genes annotated in human

succinate metabolic process

The chemical reactions and pathways involving succinate, also known as butanedioate or ethane dicarboxylate, the dianion of succinic acid. Succinate is an important intermediate in metabolism and a component of the TCA cycle.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "succinate metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "succinate metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
INSR	insulin receptor	0.436
JAK2	Janus kinase 2	0.427
SDHA	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	0.390
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.222
PTPRB	protein tyrosine phosphatase, receptor type, B	0.215
IL2RB	interleukin 2 receptor, beta	0.201
SDHB	succinate dehydrogenase complex, subunit B, iron sulfur (Ip)	0.118	Rat
NDUFS2	NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)	0.118
PTPN3	protein tyrosine phosphatase, non-receptor type 3	0.115
NDUFS3	NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)	0.088
PTPN2	protein tyrosine phosphatase, non-receptor type 2	0.076
MDH1	malate dehydrogenase 1, NAD (soluble)	0.034
STAP2	signal transducing adaptor family member 2	0.030
NDUFV2	NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa	0.028
SUCLG1	succinate-CoA ligase, alpha subunit	0.026
ACAT1	acetyl-CoA acetyltransferase 1	0.021
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.017
NDUFA9	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa	0.015
NDUFV1	NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa	0.015
BCAR1	breast cancer anti-estrogen resistance 1	0.015
STAT5A	signal transducer and activator of transcription 5A	0.014	Mouse
NDUFA10	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa	0.013
NDUFS1	NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)	0.013
EPOR	erythropoietin receptor	0.012
SAMM50	sorting and assembly machinery component 50 homolog (S. cerevisiae)	0.012