Homo sapiens

118 known processes

SETD8

SET domain containing (lysine methyltransferase) 8

(Aliases: SET07,KMT5A,SET8,PR-Set7)

SETD8 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of striated muscle tissue development GO:0045843 11 0.989
mesodermal cell fate specification GO:0007501 2 0.988
mesodermal cell fate commitment GO:0001710 2 0.987
embryonic forelimb morphogenesis GO:0035115 4 0.985
cardiac right ventricle formation GO:0003219 1 0.981
embryonic camera type eye formation GO:0060900 2 0.978
positive regulation of monocyte chemotactic protein 1 production GO:0071639 3 0.971
cardiac chamber formation GO:0003207 2 0.962
cardiac ventricle formation GO:0003211 2 0.960
embryonic camera type eye development GO:0031076 2 0.947
aortic valve development GO:0003176 3 0.944
neural crest cell development GO:0014032 3 0.931
blood vessel maturation GO:0001955 1 0.925
hindbrain development GO:0030902 3 0.899
forelimb morphogenesis GO:0035136 4 0.883
hindlimb morphogenesis GO:0035137 2 0.877
salivary gland morphogenesis GO:0007435 4 0.876
cell proliferation involved in heart valve development GO:2000793 1 0.869
cardiac left ventricle formation GO:0003218 1 0.852
nerve development GO:0021675 4 0.850
negative regulation of muscle tissue development GO:1901862 11 0.826
internal protein amino acid acetylation GO:0006475 101 0.816
regulation of myeloid cell differentiation GO:0045637 81 0.813
cranial nerve development GO:0021545 4 0.805
positive regulation of chromatin assembly or disassembly GO:0045799 2 0.755
aortic valve morphogenesis GO:0003180 3 0.754
negative regulation of histone phosphorylation GO:0033128 2 0.751
cell fate commitment involved in formation of primary germ layer GO:0060795 6 0.738
eyelid development in camera type eye GO:0061029 2 0.738
neural tube formation GO:0001841 3 0.735
negative regulation of phosphatidylinositol 3 kinase signaling GO:0014067 4 0.729
mitral valve development GO:0003174 3 0.722
morphogenesis of embryonic epithelium GO:0016331 4 0.706
heart valve formation GO:0003188 2 0.702
monocarboxylic acid metabolic process GO:0032787 185 0.694
trophectodermal cell differentiation GO:0001829 3 0.663
regulation of cellular ketone metabolic process GO:0010565 50 0.662
embryonic eye morphogenesis GO:0048048 2 0.648
regulation of heart morphogenesis GO:2000826 4 0.634
covalent chromatin modification GO:0016569 254 0.626
neural crest cell migration GO:0001755 2 0.624
basophil differentiation GO:0030221 2 0.612
positive regulation of stem cell differentiation GO:2000738 29 0.599
chromatin modification GO:0016568 298 0.588
craniofacial suture morphogenesis GO:0097094 3 0.587
myeloid cell differentiation GO:0030099 117 0.573
endocardial cushion development GO:0003197 3 0.572
cellular amine metabolic process GO:0044106 41 0.570
atrioventricular valve development GO:0003171 3 0.569
embryonic camera type eye morphogenesis GO:0048596 2 0.559
chromatin organization GO:0006325 351 0.552
regulation of bone mineralization GO:0030500 29 0.547
histone acetylation GO:0016573 93 0.539
peptidyl lysine modification GO:0018205 144 0.523
mesodermal cell differentiation GO:0048333 10 0.499
cellular ketone metabolic process GO:0042180 80 0.486
embryonic epithelial tube formation GO:0001838 4 0.474
mitral valve morphogenesis GO:0003183 2 0.461
negative regulation of muscle organ development GO:0048635 12 0.460
blastocyst formation GO:0001825 3 0.451
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.449
cardiac septum morphogenesis GO:0060411 9 0.444
embryonic cranial skeleton morphogenesis GO:0048701 6 0.438
regulation of cellular amino acid metabolic process GO:0006521 6 0.428
internal peptidyl lysine acetylation GO:0018393 97 0.423
optic nerve development GO:0021554 2 0.423
peptide transport GO:0015833 74 0.422
lipid metabolic process GO:0006629 381 0.417
regulation of biomineral tissue development GO:0070167 31 0.417
chromatin assembly or disassembly GO:0006333 78 0.415
positive regulation of myeloid cell differentiation GO:0045639 39 0.414
peptidyl lysine acetylation GO:0018394 101 0.411
regulation of muscle tissue development GO:1901861 26 0.402
primary neural tube formation GO:0014020 3 0.394
negative regulation of skeletal muscle tissue development GO:0048642 2 0.393
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.386
protein acylation GO:0043543 138 0.376
regulation of cellular amine metabolic process GO:0033238 11 0.374
amine metabolic process GO:0009308 44 0.374
cerebellum development GO:0021549 2 0.373
negative regulation of cytokine production GO:0001818 82 0.359
megakaryocyte differentiation GO:0030219 25 0.356
negative regulation of cellular amine metabolic process GO:0033239 3 0.355
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.347
cellular lipid metabolic process GO:0044255 303 0.345
positive regulation of epithelial to mesenchymal transition GO:0010718 22 0.343
atrioventricular valve morphogenesis GO:0003181 2 0.341
dna repair GO:0006281 198 0.340
embryonic hindlimb morphogenesis GO:0035116 2 0.339
regulation of lipid catabolic process GO:0050994 23 0.336
peptide hormone secretion GO:0030072 50 0.336
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.334
hematopoietic progenitor cell differentiation GO:0002244 38 0.328
double strand break repair GO:0006302 101 0.323
lipid catabolic process GO:0016042 84 0.312
mesenchymal cell development GO:0014031 50 0.310
metencephalon development GO:0022037 2 0.304
regulation of epithelial to mesenchymal transition GO:0010717 37 0.303
immune system development GO:0002520 195 0.300
positive regulation of lipid catabolic process GO:0050996 13 0.299
neural tube closure GO:0001843 3 0.293
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.286
cellular amino acid metabolic process GO:0006520 116 0.284
lipid modification GO:0030258 84 0.279
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.276
cellular response to dna damage stimulus GO:0006974 379 0.271
pancreas development GO:0031016 19 0.270
embryonic digit morphogenesis GO:0042733 6 0.266
carboxylic acid catabolic process GO:0046395 71 0.265
regulation of tumor necrosis factor production GO:0032680 43 0.264
regulation of hormone levels GO:0010817 125 0.264
regulation of dna repair GO:0006282 47 0.264
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.262
regulation of mitotic cell cycle GO:0007346 189 0.262
positive regulation of erythrocyte differentiation GO:0045648 11 0.261
cellular lipid catabolic process GO:0044242 65 0.261
regulation of muscle organ development GO:0048634 27 0.256
oxidation reduction process GO:0055114 396 0.253
regulation of response to dna damage stimulus GO:2001020 94 0.253
regulation of striated muscle tissue development GO:0016202 26 0.248
cardiac chamber development GO:0003205 30 0.242
positive regulation of binding GO:0051099 45 0.242
regulation of stem cell differentiation GO:2000736 56 0.239
second messenger mediated signaling GO:0019932 78 0.235
small molecule catabolic process GO:0044282 92 0.234
tube closure GO:0060606 3 0.234
blastocyst development GO:0001824 3 0.234
positive regulation of cellular component organization GO:0051130 376 0.232
cytokine production GO:0001816 247 0.227
ventricular cardiac muscle tissue morphogenesis GO:0055010 14 0.226
muscle organ morphogenesis GO:0048644 19 0.226
positive regulation of secretion GO:0051047 116 0.218
fatty acid metabolic process GO:0006631 115 0.218
regulation of cell cycle GO:0051726 393 0.214
ventricular cardiac muscle tissue development GO:0003229 14 0.214
peptide secretion GO:0002790 51 0.213
regulation of fatty acid beta oxidation GO:0031998 8 0.213
epithelial to mesenchymal transition GO:0001837 48 0.207
organic acid catabolic process GO:0016054 71 0.206
positive regulation of epithelial cell proliferation GO:0050679 65 0.203
myeloid leukocyte differentiation GO:0002573 60 0.202
cation transport GO:0006812 331 0.197
lipid oxidation GO:0034440 33 0.195
regulation of transmembrane transporter activity GO:0022898 74 0.194
regulation of double strand break repair GO:2000779 22 0.194
hormone secretion GO:0046879 65 0.194
regulation of protein localization GO:0032880 296 0.189
bone mineralization GO:0030282 34 0.189
negative regulation of transmembrane transport GO:0034763 29 0.188
mitotic cell cycle GO:0000278 326 0.182
positive regulation of cell cycle GO:0045787 140 0.181
negative regulation of histone acetylation GO:0035067 6 0.178
nitrogen compound transport GO:0071705 191 0.176
positive regulation of cytokine production GO:0001819 167 0.174
negative regulation of programmed cell death GO:0043069 321 0.173
embryonic appendage morphogenesis GO:0035113 9 0.172
regulation of cytokine production GO:0001817 232 0.171
formation of primary germ layer GO:0001704 42 0.168
negative regulation of tumor necrosis factor production GO:0032720 20 0.168
stem cell development GO:0048864 69 0.167
regulation of secretion by cell GO:1903530 177 0.166
cell aging GO:0007569 52 0.166
hemopoiesis GO:0030097 180 0.164
cardiac ventricle development GO:0003231 23 0.164
mesoderm formation GO:0001707 10 0.163
osteoblast differentiation GO:0001649 92 0.162
fatty acid catabolic process GO:0009062 29 0.161
regulation of establishment of protein localization GO:0070201 242 0.159
odontogenesis GO:0042476 25 0.159
regulation of transcription regulatory region dna binding GO:2000677 15 0.159
amide transport GO:0042886 76 0.158
chemokine production GO:0032602 32 0.157
cardiac chamber morphogenesis GO:0003206 26 0.157
regulation of histone acetylation GO:0035065 19 0.155
regulation of cellular component biogenesis GO:0044087 281 0.154
monocarboxylic acid catabolic process GO:0072329 37 0.152
regulation of erythrocyte differentiation GO:0045646 17 0.150
monovalent inorganic cation transport GO:0015672 128 0.149
regulation of protein transport GO:0051223 213 0.146
positive regulation of cellular component biogenesis GO:0044089 158 0.146
positive regulation of cellular component movement GO:0051272 181 0.146
regulation of cytokine secretion GO:0050707 57 0.143
negative regulation of protein metabolic process GO:0051248 391 0.142
regulation of lipid metabolic process GO:0019216 96 0.142
positive regulation of dna binding GO:0043388 17 0.142
positive regulation of secretion by cell GO:1903532 108 0.142
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.142
negative regulation of cellular protein metabolic process GO:0032269 353 0.141
regulation of dna binding GO:0051101 37 0.141
regulation of transmembrane transport GO:0034762 139 0.141
monocyte chemotactic protein 1 production GO:0071605 6 0.140
negative regulation of cell death GO:0060548 345 0.138
positive regulation of transport GO:0051050 336 0.137
positive regulation of organelle organization GO:0010638 195 0.136
positive regulation of cell proliferation GO:0008284 301 0.135
embryonic limb morphogenesis GO:0030326 9 0.135
regulation of secretion GO:0051046 194 0.134
actin filament based process GO:0030029 224 0.133
signal transduction in response to dna damage GO:0042770 57 0.132
negative regulation of histone modification GO:0031057 19 0.131
negative regulation of cellular component organization GO:0051129 235 0.131
hematopoietic or lymphoid organ development GO:0048534 186 0.131
cardiac muscle tissue development GO:0048738 39 0.131
regulation of ion transport GO:0043269 189 0.131
hydrogen transport GO:0006818 23 0.130
interleukin 6 production GO:0032635 37 0.129
regulation of binding GO:0051098 111 0.128
muscle tissue development GO:0060537 62 0.128
negative regulation of cellular senescence GO:2000773 5 0.127
positive regulation of catabolic process GO:0009896 310 0.127
bone development GO:0060348 26 0.127
positive regulation of cell motility GO:2000147 177 0.127
mesenchymal cell differentiation GO:0048762 52 0.123
regulation of cell differentiation GO:0045595 393 0.123
positive regulation of protein transport GO:0051222 135 0.122
hormone transport GO:0009914 68 0.121
regulation of transporter activity GO:0032409 82 0.121
gland morphogenesis GO:0022612 8 0.119
regulation of cellular senescence GO:2000772 13 0.118
histone modification GO:0016570 251 0.117
cellular response to oxygen levels GO:0071453 55 0.116
anatomical structure formation involved in morphogenesis GO:0048646 284 0.116
signal release GO:0023061 70 0.115
regulation of cellular response to stress GO:0080135 244 0.115
cellular response to decreased oxygen levels GO:0036294 51 0.115
epithelial tube morphogenesis GO:0060562 38 0.115
appendage morphogenesis GO:0035107 16 0.114
regulation of signal transduction by p53 class mediator GO:1901796 26 0.113
positive regulation of cellular catabolic process GO:0031331 284 0.111
regulation of peroxisome proliferator activated receptor signaling pathway GO:0035358 4 0.110
erythrocyte homeostasis GO:0034101 31 0.109
fatty acid oxidation GO:0019395 31 0.109
positive regulation of fatty acid metabolic process GO:0045923 11 0.108
negative regulation of developmental process GO:0051093 247 0.108
cellular senescence GO:0090398 34 0.108
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.107
positive regulation of locomotion GO:0040017 186 0.106
proton transport GO:0015992 22 0.106
positive regulation of fatty acid beta oxidation GO:0032000 5 0.105
secretion by cell GO:0032940 226 0.105
negative regulation of organelle organization GO:0010639 126 0.104
regulation of cellular component movement GO:0051270 334 0.103
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.102
regulation of fatty acid metabolic process GO:0019217 24 0.102
negative regulation of transport GO:0051051 176 0.101
heart morphogenesis GO:0003007 48 0.099
negative regulation of multicellular organismal process GO:0051241 317 0.098
positive regulation of cell development GO:0010720 92 0.095
cellular response to hypoxia GO:0071456 51 0.095
intracellular receptor signaling pathway GO:0030522 104 0.094
negative regulation of response to dna damage stimulus GO:2001021 33 0.093
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 22 0.092
negative regulation of phosphorus metabolic process GO:0010563 267 0.092
granulocyte differentiation GO:0030851 16 0.092
positive regulation of protein secretion GO:0050714 60 0.090
negative regulation of chromatin modification GO:1903309 21 0.090
negative regulation of cell differentiation GO:0045596 171 0.090
striated muscle cell differentiation GO:0051146 43 0.090
epithelium development GO:0060429 227 0.090
regulation of dna metabolic process GO:0051052 153 0.089
biomineral tissue development GO:0031214 39 0.089
muscle fiber development GO:0048747 16 0.088
mesenchyme development GO:0060485 59 0.086
tumor necrosis factor production GO:0032640 43 0.086
palate development GO:0060021 13 0.086
positive regulation of mitotic cell cycle GO:0045931 60 0.085
negative regulation of intracellular signal transduction GO:1902532 183 0.085
regulation of protein secretion GO:0050708 86 0.085
regulation of cell motility GO:2000145 299 0.085
negative regulation of protein phosphorylation GO:0001933 140 0.083
negative regulation of phosphorylation GO:0042326 174 0.083
negative regulation of transporter activity GO:0032410 25 0.083
cell cell signaling GO:0007267 155 0.082
negative regulation of chromosome organization GO:2001251 48 0.081
positive regulation of transcription regulatory region dna binding GO:2000679 8 0.080
signal transduction by p53 class mediator GO:0072331 72 0.080
muscle cell development GO:0055001 29 0.080
positive regulation of homeostatic process GO:0032846 47 0.080
ameboidal type cell migration GO:0001667 135 0.080
positive regulation of developmental process GO:0051094 314 0.079
epithelial cell proliferation GO:0050673 128 0.079
nervous system development GO:0007399 293 0.078
cell division GO:0051301 168 0.077
cellular component morphogenesis GO:0032989 314 0.077
digestive tract development GO:0048565 75 0.076
cardiac muscle tissue morphogenesis GO:0055008 18 0.076
vasculature development GO:0001944 181 0.075
regulation of cell morphogenesis GO:0022604 153 0.075
cell fate determination GO:0001709 3 0.075
gastrulation GO:0007369 51 0.074
regulation of homeostatic process GO:0032844 121 0.074
actin cytoskeleton organization GO:0030036 207 0.074
response to hypoxia GO:0001666 96 0.074
regulation of locomotion GO:0040012 329 0.072
positive regulation of chromosome organization GO:2001252 41 0.071
cell morphogenesis GO:0000902 296 0.071
muscle cell differentiation GO:0042692 63 0.071
positive regulation of cell division GO:0051781 59 0.071
ossification GO:0001503 121 0.070
muscle structure development GO:0061061 98 0.070
cytokine secretion GO:0050663 64 0.070
regulation of protein acetylation GO:1901983 25 0.069
muscle tissue morphogenesis GO:0060415 19 0.068
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 35 0.068
regulation of epithelial cell proliferation GO:0050678 113 0.067
segmentation GO:0035282 4 0.067
negative regulation of dna metabolic process GO:0051053 57 0.067
negative regulation of ossification GO:0030279 21 0.067
positive regulation of chemokine production GO:0032722 22 0.066
cell development GO:0048468 328 0.065
erythrocyte differentiation GO:0030218 28 0.065
mesoderm morphogenesis GO:0048332 11 0.065
blood vessel development GO:0001568 172 0.065
cardiac septum development GO:0003279 13 0.065
limb development GO:0060173 23 0.064
regulation of chromatin assembly or disassembly GO:0001672 6 0.064
post embryonic development GO:0009791 2 0.063
positive regulation of tumor necrosis factor production GO:0032760 21 0.063
response to decreased oxygen levels GO:0036293 96 0.063
protein secretion GO:0009306 98 0.062
regulation of cell division GO:0051302 116 0.062
fatty acid beta oxidation GO:0006635 22 0.061
heart development GO:0007507 95 0.061
digestive tract morphogenesis GO:0048546 56 0.059
regulation of anatomical structure morphogenesis GO:0022603 286 0.059
regulation of cell development GO:0060284 161 0.059
morphogenesis of an epithelium GO:0002009 60 0.058
regulation of monocyte chemotactic protein 1 production GO:0071637 6 0.057
limb morphogenesis GO:0035108 16 0.057
positive regulation of interleukin 6 production GO:0032755 21 0.057
regulation of peptidyl lysine acetylation GO:2000756 22 0.056
cardiocyte differentiation GO:0035051 23 0.056
regulation of interleukin 6 production GO:0032675 37 0.055
muscle organ development GO:0007517 56 0.054
behavior GO:0007610 112 0.054
head development GO:0060322 108 0.054
regulation of chromosome organization GO:0033044 103 0.054
response to carbohydrate GO:0009743 21 0.053
negative regulation of peptidyl lysine acetylation GO:2000757 8 0.053
generation of neurons GO:0048699 152 0.052
cardiovascular system development GO:0072358 262 0.051
myeloid cell homeostasis GO:0002262 34 0.051
homeostasis of number of cells GO:0048872 40 0.050
multicellular organismal aging GO:0010259 3 0.050
response to growth factor GO:0070848 205 0.050
central nervous system development GO:0007417 123 0.050
negative regulation of protein acetylation GO:1901984 11 0.050
response to oxygen levels GO:0070482 100 0.049
bone morphogenesis GO:0060349 10 0.049
neurogenesis GO:0022008 169 0.049
regulation of skeletal muscle tissue development GO:0048641 15 0.048
regulation of cell aging GO:0090342 18 0.048
phosphatidylinositol mediated signaling GO:0048015 55 0.048
retinoic acid biosynthetic process GO:0002138 2 0.048
immune response GO:0006955 307 0.047
stem cell differentiation GO:0048863 93 0.047
tissue morphogenesis GO:0048729 96 0.047
neural tube development GO:0021915 9 0.047
vesicle mediated transport GO:0016192 371 0.047
striated muscle cell development GO:0055002 27 0.046
growth GO:0040007 202 0.046
circulatory system development GO:0072359 262 0.046
histone methylation GO:0016571 60 0.045
organ morphogenesis GO:0009887 147 0.045
brain development GO:0007420 97 0.045
anatomical structure maturation GO:0071695 9 0.045
regulation of organ morphogenesis GO:2000027 24 0.044
tube development GO:0035295 125 0.043
neuroblast proliferation GO:0007405 4 0.043
cellular response to growth factor stimulus GO:0071363 197 0.043
histone phosphorylation GO:0016572 16 0.043
gland development GO:0048732 48 0.043
tube morphogenesis GO:0035239 95 0.042
posttranscriptional regulation of gene expression GO:0010608 213 0.042
regulation of chromatin modification GO:1903308 51 0.041
digestive system development GO:0055123 75 0.041
regulation of chromatin organization GO:1902275 56 0.041
positive regulation of cell differentiation GO:0045597 211 0.040
phosphatidylinositol 3 kinase signaling GO:0014065 48 0.040
regeneration GO:0031099 4 0.040
protein catabolic process GO:0030163 325 0.040
cellular macromolecular complex assembly GO:0034622 324 0.040
embryonic morphogenesis GO:0048598 85 0.039
regulation of histone modification GO:0031056 47 0.039
reproductive process GO:0022414 106 0.039
protein modification by small protein conjugation GO:0032446 342 0.039
appendage development GO:0048736 23 0.038
mesoderm development GO:0007498 14 0.038
mitotic cell cycle process GO:1903047 286 0.038
determination of adult lifespan GO:0008340 2 0.038
negative regulation of catalytic activity GO:0043086 335 0.038
negative regulation of tumor necrosis factor superfamily cytokine production GO:1903556 20 0.038
eye morphogenesis GO:0048592 16 0.037
embryonic skeletal system development GO:0048706 13 0.037
cell morphogenesis involved in differentiation GO:0000904 144 0.037
heart valve morphogenesis GO:0003179 8 0.036
neural crest cell differentiation GO:0014033 5 0.036
chordate embryonic development GO:0043009 34 0.036
pharynx development GO:0060465 1 0.035
actomyosin structure organization GO:0031032 59 0.035
positive regulation of interleukin 6 secretion GO:2000778 6 0.035
locomotory behavior GO:0007626 1 0.035
histone lysine methylation GO:0034968 50 0.034
female gamete generation GO:0007292 2 0.034
inositol lipid mediated signaling GO:0048017 55 0.033
cytoplasmic transport GO:0016482 379 0.033
nucleoside phosphate catabolic process GO:1901292 412 0.032
membrane organization GO:0061024 292 0.032
skeletal system development GO:0001501 79 0.032
regulation of fatty acid oxidation GO:0046320 9 0.032
methylation GO:0032259 106 0.032
ribonucleoside triphosphate catabolic process GO:0009203 391 0.031
apoptotic signaling pathway GO:0097190 268 0.031
negative regulation of cell cycle GO:0045786 193 0.031
macromolecule methylation GO:0043414 97 0.030
outflow tract morphogenesis GO:0003151 10 0.030
single organism membrane organization GO:0044802 268 0.030
response to monosaccharide GO:0034284 20 0.030
protein processing GO:0016485 226 0.030
neuron migration GO:0001764 11 0.030
cellular macromolecule catabolic process GO:0044265 380 0.029
positive regulation of immune system process GO:0002684 283 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.029
nitric oxide mediated signal transduction GO:0007263 7 0.028
protein ubiquitination GO:0016567 314 0.028
aging GO:0007568 66 0.028
protein maturation GO:0051604 233 0.028
forebrain generation of neurons GO:0021872 3 0.028
cell adhesion GO:0007155 325 0.028
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.028
oogenesis GO:0048477 2 0.028
limbic system development GO:0021761 3 0.028
developmental maturation GO:0021700 28 0.027
regulation of cell cycle process GO:0010564 266 0.027
response to abiotic stimulus GO:0009628 336 0.027
extrinsic apoptotic signaling pathway GO:0097191 119 0.027
protein acetylation GO:0006473 116 0.027
response to hexose GO:0009746 20 0.027
diterpenoid biosynthetic process GO:0016102 2 0.027
modification dependent macromolecule catabolic process GO:0043632 212 0.027
protein polyubiquitination GO:0000209 110 0.027
organophosphate catabolic process GO:0046434 430 0.026
purine nucleoside triphosphate metabolic process GO:0009144 412 0.026
somitogenesis GO:0001756 2 0.026
cell fate specification GO:0001708 8 0.026
regulation of proteolysis GO:0030162 293 0.026
carboxylic acid biosynthetic process GO:0046394 97 0.026
developmental programmed cell death GO:0010623 3 0.026
epithelial cell differentiation GO:0030855 141 0.026
stem cell division GO:0017145 2 0.026
cardiac left ventricle morphogenesis GO:0003214 6 0.025
single organism reproductive process GO:0044702 98 0.025
biological adhesion GO:0022610 331 0.025
negative regulation of hydrolase activity GO:0051346 182 0.025
microtubule based process GO:0007017 210 0.025
cellular protein catabolic process GO:0044257 261 0.025
tissue regeneration GO:0042246 3 0.025
ubiquitin dependent protein catabolic process GO:0006511 206 0.024
intracellular protein transport GO:0006886 270 0.024
glycosyl compound catabolic process GO:1901658 413 0.024
regulation of peptidase activity GO:0052547 180 0.024
positive regulation of cellular amine metabolic process GO:0033240 7 0.024
ribonucleoside triphosphate metabolic process GO:0009199 412 0.023
purine nucleoside triphosphate catabolic process GO:0009146 392 0.023
rna interference GO:0016246 4 0.023
cellular protein complex assembly GO:0043623 188 0.023
regulation of endopeptidase activity GO:0052548 170 0.023
ras protein signal transduction GO:0007265 73 0.023
response to oxygen containing compound GO:1901700 369 0.023
regulation of apoptotic signaling pathway GO:2001233 175 0.022
cellular response to endogenous stimulus GO:0071495 336 0.022
regulation of cell migration GO:0030334 289 0.022
embryo development GO:0009790 123 0.022
purine ribonucleoside catabolic process GO:0046130 398 0.022
negative regulation of locomotion GO:0040013 118 0.022
purine containing compound catabolic process GO:0072523 411 0.022
modification dependent protein catabolic process GO:0019941 209 0.022
regulation of intracellular transport GO:0032386 195 0.022
wnt signaling pathway GO:0016055 156 0.021
hippocampus development GO:0021766 1 0.021
forebrain neuron differentiation GO:0021879 3 0.021
microtubule cytoskeleton organization GO:0000226 176 0.021
reproduction GO:0000003 63 0.021
endomembrane system organization GO:0010256 196 0.020
chemical homeostasis GO:0048878 306 0.020
carbohydrate derivative biosynthetic process GO:1901137 207 0.020
embryonic organ development GO:0048568 36 0.020
secretion GO:0046903 254 0.020
oocyte differentiation GO:0009994 2 0.020
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 4 0.020
neural retina development GO:0003407 8 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.020

SETD8 disease predictions

Disease DO term ID Size Probability Func Analog Org
bone development disease DOID:0080006 55 0.550
bone disease DOID:0080001 88 0.550
musculoskeletal system disease DOID:17 223 0.550
connective tissue disease DOID:65 109 0.550
dysostosis DOID:1934 22 0.458
synostosis DOID:11971 10 0.067