IMP

Process View

10 genes annotated in human

synostosis

DOID:11971

A dysostosis that results in abnormal fusing of adjacent bones.

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Known genes in the process in human Include functional analogs

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Name	Description	Probability	Func Analog Organism
TJP1	tight junction protein 1 (zona occludens 1)	0.605
FGF1	fibroblast growth factor 1 (acidic)	0.307
SMAD3	SMAD family member 3	0.095
FGF2	fibroblast growth factor 2 (basic)	0.080
FGF10	fibroblast growth factor 10	0.079
SETD8	SET domain containing (lysine methyltransferase) 8	0.067
FGFR2	fibroblast growth factor receptor 2	0.037
FRS2	fibroblast growth factor receptor substrate 2	0.034
FGFR1	fibroblast growth factor receptor 1	0.031
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.022
SMAD4	SMAD family member 4	0.021
FGF7	fibroblast growth factor 7	0.016
SKIL	SKI-like oncogene	0.015	Human
ESPL1	extra spindle pole bodies homolog 1 (S. cerevisiae)	0.015
PLCG1	phospholipase C, gamma 1	0.014
SMAD1	SMAD family member 1	0.011
STK36	serine/threonine kinase 36	0.010
LAT	linker for activation of T cells	0.010
GLI3	GLI family zinc finger 3	0.004
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.004
MSX2	msh homeobox 2	0.002
GJA1	gap junction protein, alpha 1, 43kDa	0.002
TWIST1	twist homolog 1 (Drosophila)	0.001
HOXD13	homeobox D13	0.001
RECQL4	RecQ protein-like 4	0.001
LMBR1	limb region 1 homolog (mouse)	0.001