Homo sapiens

25 known processes

SLC6A3

solute carrier family 6 (neurotransmitter transporter, dopamine), member 3

(Aliases: DAT,DAT1)

SLC6A3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cerebral cortex gabaergic interneuron differentiation GO:0021892 1 1.000
auditory behavior GO:0031223 4 0.999
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 2 0.999
gabaergic neuron differentiation GO:0097154 1 0.984
regulation of synaptic transmission dopaminergic GO:0032225 4 0.976
catecholamine secretion GO:0050432 1 0.973
negative regulation of voltage gated calcium channel activity GO:1901386 4 0.968
negative regulation of amine transport GO:0051953 1 0.939
regulation of catecholamine secretion GO:0050433 1 0.929
negative regulation of cytosolic calcium ion concentration GO:0051481 1 0.927
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 6 0.926
catecholamine transport GO:0051937 6 0.922
serotonin uptake GO:0051610 2 0.917
Human
glycine import GO:0036233 1 0.858
Human
regulation of excretion GO:0044062 1 0.857
dopamine uptake involved in synaptic transmission GO:0051583 4 0.848
norepinephrine transport GO:0015874 1 0.845
pituitary gland development GO:0021983 2 0.838
regulation of dopamine uptake involved in synaptic transmission GO:0051584 4 0.830
sodium ion homeostasis GO:0055078 14 0.786
regulation of amine transport GO:0051952 5 0.780
startle response GO:0001964 3 0.777
regulation of cyclase activity GO:0031279 19 0.762
g protein coupled receptor signaling pathway GO:0007186 207 0.752
cyclic nucleotide biosynthetic process GO:0009190 61 0.737
regulation of neurotransmitter secretion GO:0046928 3 0.716
monoamine transport GO:0015844 10 0.716
camp biosynthetic process GO:0006171 47 0.709
organic hydroxy compound transport GO:0015850 63 0.703
negative regulation of synaptic transmission GO:0050805 2 0.687
regulation of receptor internalization GO:0002090 15 0.684
positive regulation of sodium proton antiporter activity GO:0032417 3 0.681
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.675
positive regulation of neurotransmitter transport GO:0051590 1 0.669
positive regulation of receptor internalization GO:0002092 12 0.652
positive regulation of synaptic transmission GO:0050806 4 0.638
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 43 0.638
regulation of synaptic plasticity GO:0048167 3 0.638
receptor internalization GO:0031623 43 0.637
cell cell signaling GO:0007267 155 0.636
Human
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 22 0.633
neurotransmitter transport GO:0006836 10 0.623
Human Rat
regulation of neurotransmitter levels GO:0001505 15 0.556
Human
receptor metabolic process GO:0043112 81 0.517
metal ion homeostasis GO:0055065 169 0.515
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.487
regulation of neuronal synaptic plasticity GO:0048168 1 0.487
positive regulation of amine transport GO:0051954 2 0.479
positive regulation of catecholamine uptake involved in synaptic transmission GO:0051944 1 0.469
substrate independent telencephalic tangential migration GO:0021826 0 0.456
response to auditory stimulus GO:0010996 4 0.451
calcium ion transmembrane transport GO:0070588 76 0.446
negative regulation of cell death GO:0060548 345 0.439
cytosolic calcium ion homeostasis GO:0051480 89 0.432
neurotransmitter uptake GO:0001504 5 0.428
Human
locomotory behavior GO:0007626 1 0.427
regulation of camp metabolic process GO:0030814 52 0.424
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 18 0.413
organic anion transport GO:0015711 103 0.413
Human
positive regulation of cellular component organization GO:0051130 376 0.407
regulation of calcium ion transport GO:0051924 79 0.396
long term synaptic potentiation GO:0060291 1 0.390
sodium ion transmembrane transport GO:0035725 59 0.389
Human Rat
cellular metal ion homeostasis GO:0006875 146 0.382
cyclic purine nucleotide metabolic process GO:0052652 60 0.379
metal ion transport GO:0030001 272 0.376
Human Rat
organic hydroxy compound metabolic process GO:1901615 147 0.373
positive regulation of neural precursor cell proliferation GO:2000179 2 0.372
synaptic transmission glycinergic GO:0060012 1 0.371
Human
cellular chemical homeostasis GO:0055082 180 0.360
phospholipid metabolic process GO:0006644 99 0.359
regulation of cell differentiation GO:0045595 393 0.351
adult locomotory behavior GO:0008344 1 0.349
secretion GO:0046903 254 0.345
regulation of neurotransmitter uptake GO:0051580 4 0.344
sensory perception of smell GO:0007608 2 0.343
catecholamine uptake involved in synaptic transmission GO:0051934 4 0.343
calcium ion homeostasis GO:0055074 122 0.341
circadian sleep wake cycle GO:0042745 2 0.330
positive regulation of neurotransmitter uptake GO:0051582 1 0.322
inorganic ion transmembrane transport GO:0098660 231 0.322
Human Rat
adenylate cyclase activating dopamine receptor signaling pathway GO:0007191 3 0.320
nitrogen compound transport GO:0071705 191 0.316
glycine transport GO:0015816 3 0.314
Human
positive regulation of transport GO:0051050 336 0.310
sequestering of metal ion GO:0051238 24 0.307
cation transport GO:0006812 331 0.304
associative learning GO:0008306 1 0.304
regulation of adenylate cyclase activity GO:0045761 17 0.302
organic acid transport GO:0015849 65 0.301
Human
positive regulation of ion transmembrane transporter activity GO:0032414 29 0.298
response to histamine GO:0034776 6 0.287
regulation of lyase activity GO:0051339 23 0.286
carboxylic acid transport GO:0046942 63 0.283
Human
divalent metal ion transport GO:0070838 152 0.282
cell development GO:0048468 328 0.282
nervous system development GO:0007399 293 0.279
Human
regulation of catecholamine uptake involved in synaptic transmission GO:0051940 4 0.278
regulation of receptor mediated endocytosis GO:0048259 32 0.275
behavioral response to ethanol GO:0048149 2 0.272
vesicle mediated transport GO:0016192 371 0.272
circadian behavior GO:0048512 2 0.269
synaptic transmission cholinergic GO:0007271 2 0.269
ion transmembrane transport GO:0034220 338 0.268
ion homeostasis GO:0050801 230 0.264
regulation of protein complex assembly GO:0043254 147 0.263
cellular divalent inorganic cation homeostasis GO:0072503 128 0.259
regulation of cellular component biogenesis GO:0044087 281 0.250
sequestering of calcium ion GO:0051208 17 0.247
synaptic transmission dopaminergic GO:0001963 5 0.244
regulation of secretion GO:0051046 194 0.243
positive regulation of ion transport GO:0043270 87 0.242
atp metabolic process GO:0046034 176 0.241
transmembrane transport GO:0055085 399 0.238
cellular protein complex assembly GO:0043623 188 0.237
camp metabolic process GO:0046058 61 0.237
positive regulation of protein polymerization GO:0032273 45 0.237
release of sequestered calcium ion into cytosol GO:0051209 41 0.236
regulation of circadian sleep wake cycle GO:0042749 2 0.235
regulation of cyclic nucleotide biosynthetic process GO:0030802 49 0.232
regulation of purine nucleotide biosynthetic process GO:1900371 50 0.231
cellular lipid metabolic process GO:0044255 303 0.231
neuroblast proliferation GO:0007405 4 0.229
sleep GO:0030431 2 0.229
circadian sleep wake cycle process GO:0022410 2 0.227
regulation of camp biosynthetic process GO:0030817 45 0.227
regulation of neural precursor cell proliferation GO:2000177 4 0.222
forebrain neuron development GO:0021884 2 0.216
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 15 0.216
long chain fatty acid transport GO:0015909 18 0.215
positive regulation of synaptic transmission dopaminergic GO:0032226 1 0.214
purine ribonucleoside metabolic process GO:0046128 437 0.213
positive regulation of protein phosphorylation GO:0001934 313 0.210
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.208
forebrain neuron differentiation GO:0021879 3 0.206
inorganic cation transmembrane transport GO:0098662 194 0.205
Human Rat
mechanosensory behavior GO:0007638 4 0.203
purine ribonucleotide biosynthetic process GO:0009152 79 0.203
signal release GO:0023061 70 0.201
regulation of establishment of protein localization GO:0070201 242 0.201
regulation of secretion by cell GO:1903530 177 0.201
limbic system development GO:0021761 3 0.199
chemical homeostasis GO:0048878 306 0.197
cation homeostasis GO:0055080 189 0.197
dopamine uptake GO:0090494 4 0.195
cation transmembrane transport GO:0098655 238 0.193
rhythmic behavior GO:0007622 2 0.192
regulation of protein localization GO:0032880 296 0.189
regulation of nucleotide biosynthetic process GO:0030808 50 0.187
cellular macromolecular complex assembly GO:0034622 324 0.187
response to abiotic stimulus GO:0009628 336 0.186
positive regulation of endocytosis GO:0045807 42 0.183
regulation of locomotion GO:0040012 329 0.182
amino acid transport GO:0006865 28 0.182
Human
cellular cation homeostasis GO:0030003 163 0.182
neuron neuron synaptic transmission GO:0007270 6 0.181
Human
proline transport GO:0015824 4 0.181
Human
positive regulation of secretion by cell GO:1903532 108 0.177
divalent inorganic cation transport GO:0072511 158 0.176
negative regulation of ion transmembrane transport GO:0034766 26 0.175
secretion by cell GO:0032940 226 0.174
purinergic receptor signaling pathway GO:0035587 8 0.174
organophosphate catabolic process GO:0046434 430 0.172
membrane organization GO:0061024 292 0.169
nucleoside triphosphate metabolic process GO:0009141 422 0.168
calcium ion transport into cytosol GO:0060402 48 0.165
cellular ketone metabolic process GO:0042180 80 0.165
calcium ion transport GO:0006816 147 0.165
regulation of ion transmembrane transporter activity GO:0032412 72 0.163
anion transport GO:0006820 161 0.163
Human
regulation of transporter activity GO:0032409 82 0.161
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.159
nucleoside monophosphate metabolic process GO:0009123 191 0.159
memory GO:0007613 3 0.158
negative regulation of cellular component organization GO:0051129 235 0.155
regulation of protein polymerization GO:0032271 63 0.154
ribonucleoside triphosphate metabolic process GO:0009199 412 0.153
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.152
dopamine transport GO:0015872 5 0.151
phospholipase c activating dopamine receptor signaling pathway GO:0060158 2 0.151
nucleoside phosphate biosynthetic process GO:1901293 109 0.149
acid secretion GO:0046717 12 0.147
positive regulation of protein complex assembly GO:0031334 86 0.147
response to oxygen levels GO:0070482 100 0.147
negative regulation of secretion GO:0051048 58 0.145
regulation of neuroblast proliferation GO:1902692 3 0.145
divalent inorganic cation homeostasis GO:0072507 136 0.144
positive regulation of cellular amine metabolic process GO:0033240 7 0.144
regulation of hormone levels GO:0010817 125 0.144
cellular homeostasis GO:0019725 196 0.143
response to transition metal nanoparticle GO:1990267 29 0.143
Rat
regulation of ion homeostasis GO:2000021 73 0.142
regulation of g protein coupled receptor protein signaling pathway GO:0008277 35 0.141
negative regulation of sequestering of calcium ion GO:0051283 41 0.141
regulation of sequestering of calcium ion GO:0051282 41 0.138
cellular calcium ion homeostasis GO:0006874 117 0.138
regulation of excitatory postsynaptic membrane potential GO:0060079 1 0.138
regulation of cellular component movement GO:0051270 334 0.136
positive regulation of phosphorylation GO:0042327 394 0.135
forebrain development GO:0030900 26 0.133
Human
visual learning GO:0008542 1 0.133
lipid metabolic process GO:0006629 381 0.131
negative regulation of catalytic activity GO:0043086 335 0.130
protein polymerization GO:0051258 71 0.130
arachidonic acid secretion GO:0050482 7 0.129
cytoplasmic transport GO:0016482 379 0.128
sodium ion transport GO:0006814 61 0.127
Human Rat
response to organic cyclic compound GO:0014070 204 0.126
Rat
circadian sleep wake cycle sleep GO:0050802 2 0.126
purine ribonucleoside catabolic process GO:0046130 398 0.126
regulation of synaptic transmission GO:0050804 11 0.125
response to drug GO:0042493 81 0.124
Rat
organonitrogen compound biosynthetic process GO:1901566 200 0.124
positive regulation of organic acid transport GO:0032892 3 0.123
regulation of transmembrane transporter activity GO:0022898 74 0.123
response to axon injury GO:0048678 1 0.122
negative regulation of transport GO:0051051 176 0.121
purine nucleoside monophosphate metabolic process GO:0009126 186 0.120
lipid localization GO:0010876 106 0.120
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.120
positive regulation of sodium ion transmembrane transporter activity GO:2000651 6 0.119
serotonin transport GO:0006837 3 0.118
Human
long term memory GO:0007616 2 0.118
lipid transport GO:0006869 90 0.118
icosanoid transport GO:0071715 11 0.117
regulation of sodium ion transmembrane transport GO:1902305 23 0.116
positive regulation of transferase activity GO:0051347 227 0.116
regulation of calcium ion transmembrane transporter activity GO:1901019 28 0.115
response to alcohol GO:0097305 64 0.114
Rat
positive regulation of neuroblast proliferation GO:0002052 2 0.113
negative regulation of multicellular organismal process GO:0051241 317 0.113
ribonucleoside monophosphate catabolic process GO:0009158 158 0.113
negative regulation of actin nucleation GO:0051126 3 0.112
negative regulation of locomotion GO:0040013 118 0.112
regulation of protein secretion GO:0050708 86 0.111
positive regulation of secretion GO:0051047 116 0.111
cellular amine metabolic process GO:0044106 41 0.109
positive regulation of transporter activity GO:0032411 32 0.108
regulation of protein kinase activity GO:0045859 289 0.107
neurotransmitter secretion GO:0007269 4 0.107
cytokinesis GO:0000910 96 0.107
regulation of kinase activity GO:0043549 314 0.107
regulation of heart rate GO:0002027 38 0.107
positive regulation of g protein coupled receptor protein signaling pathway GO:0045745 9 0.106
negative regulation of transporter activity GO:0032410 25 0.106
nucleoside phosphate catabolic process GO:1901292 412 0.105
positive regulation of inositol phosphate biosynthetic process GO:0060732 2 0.104
ribose phosphate biosynthetic process GO:0046390 82 0.104
negative regulation of intracellular signal transduction GO:1902532 183 0.103
regulation of cellular amine metabolic process GO:0033238 11 0.103
ribonucleotide catabolic process GO:0009261 405 0.103
visual behavior GO:0007632 2 0.103
nucleoside monophosphate catabolic process GO:0009125 159 0.102
regulation of purine nucleotide metabolic process GO:1900542 264 0.102
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.101
regulation of ion transport GO:0043269 189 0.100
amine transport GO:0015837 7 0.099
ribonucleotide biosynthetic process GO:0009260 81 0.099
cell morphogenesis GO:0000902 296 0.099
erk1 and erk2 cascade GO:0070371 104 0.098
regulation of neurotransmitter transport GO:0051588 7 0.098
nucleoside catabolic process GO:0009164 408 0.098
monovalent inorganic cation transport GO:0015672 128 0.098
Human Rat
negative regulation of phosphate metabolic process GO:0045936 267 0.098
negative regulation of secretion by cell GO:1903531 52 0.098
purine nucleoside triphosphate metabolic process GO:0009144 412 0.097
glycerolipid metabolic process GO:0046486 107 0.097
negative regulation of peptide hormone secretion GO:0090278 10 0.097
organophosphate biosynthetic process GO:0090407 163 0.096
purine nucleoside monophosphate catabolic process GO:0009128 158 0.096
protein localization to membrane GO:0072657 160 0.096
l amino acid import GO:0043092 4 0.095
Human
regulation of protein serine threonine kinase activity GO:0071900 179 0.095
regulation of cell motility GO:2000145 299 0.094
regulation of circadian sleep wake cycle sleep GO:0045187 2 0.093
positive regulation of ion transmembrane transport GO:0034767 40 0.092
hormone secretion GO:0046879 65 0.092
cyclic nucleotide metabolic process GO:0009187 82 0.090
regulation of erk1 and erk2 cascade GO:0070372 99 0.089
purine containing compound biosynthetic process GO:0072522 88 0.089
hydrogen transport GO:0006818 23 0.088
peptide hormone secretion GO:0030072 50 0.088
single organism membrane organization GO:0044802 268 0.087
negative regulation of blood pressure GO:0045776 3 0.087
sensory perception of chemical stimulus GO:0007606 38 0.087
muscle system process GO:0003012 81 0.087
response to oxygen containing compound GO:1901700 369 0.086
Rat
purine nucleoside triphosphate catabolic process GO:0009146 392 0.085
amine metabolic process GO:0009308 44 0.085
purine containing compound catabolic process GO:0072523 411 0.085
positive regulation of kinase activity GO:0033674 204 0.085
regulation of cellular amino acid metabolic process GO:0006521 6 0.083
regulation of endocytosis GO:0030100 72 0.083
regulation of cell development GO:0060284 161 0.083
positive regulation of dopamine uptake involved in synaptic transmission GO:0051586 1 0.083
spinal cord development GO:0021510 4 0.083
ribonucleoside triphosphate catabolic process GO:0009203 391 0.083
regulation of protein transport GO:0051223 213 0.082
histone modification GO:0016570 251 0.082
cellular amino acid metabolic process GO:0006520 116 0.082
ribonucleoside catabolic process GO:0042454 406 0.082
ribonucleoside monophosphate metabolic process GO:0009161 187 0.082
positive regulation of cytokinesis GO:0032467 29 0.081
neurogenesis GO:0022008 169 0.081
purine ribonucleotide catabolic process GO:0009154 404 0.081
positive regulation of cell cycle GO:0045787 140 0.080
phosphatidylinositol metabolic process GO:0046488 53 0.080
regulation of sodium ion transport GO:0002028 24 0.079
positive regulation of cellular component biogenesis GO:0044089 158 0.078
regulation of cation channel activity GO:2001257 33 0.077
response to inorganic substance GO:0010035 127 0.077
Rat
negative regulation of protein modification process GO:0031400 200 0.077
synaptic transmission GO:0007268 61 0.077
Human
regulation of metal ion transport GO:0010959 120 0.076
regulation of cellular ketone metabolic process GO:0010565 50 0.076
system process GO:0003008 349 0.076
regulation of vesicle mediated transport GO:0060627 130 0.076
negative regulation of ion transport GO:0043271 39 0.076
peptide transport GO:0015833 74 0.076
brain development GO:0007420 97 0.075
Human
negative regulation of organelle organization GO:0010639 126 0.075
cytosolic calcium ion transport GO:0060401 48 0.075
response to radiation GO:0009314 151 0.075
regulation of nucleotide metabolic process GO:0006140 269 0.075
positive regulation of cell proliferation GO:0008284 301 0.074
maintenance of location GO:0051235 112 0.074
amide transport GO:0042886 76 0.074
adenylate cyclase inhibiting dopamine receptor signaling pathway GO:0007195 4 0.073
regulation of dopamine receptor signaling pathway GO:0060159 3 0.073
response to cocaine GO:0042220 1 0.073
negative regulation of endopeptidase activity GO:0010951 84 0.073
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.073
positive regulation of homeostatic process GO:0032846 47 0.073
neuron fate commitment GO:0048663 2 0.073
response to decreased oxygen levels GO:0036293 96 0.073
purine nucleoside catabolic process GO:0006152 398 0.073
regulation of sodium ion transmembrane transporter activity GO:2000649 17 0.072
glycosyl compound catabolic process GO:1901658 413 0.072
nucleotide catabolic process GO:0009166 408 0.072
regulation of cell cycle process GO:0010564 266 0.072
cell projection organization GO:0030030 252 0.071
regulation of proteolysis GO:0030162 293 0.071
endocytosis GO:0006897 159 0.071
intracellular protein transport GO:0006886 270 0.070
positive regulation of transmembrane transport GO:0034764 41 0.070
wnt signaling pathway GO:0016055 156 0.069
cellular component morphogenesis GO:0032989 314 0.069
catecholamine uptake GO:0090493 4 0.069
dopamine receptor signaling pathway GO:0007212 10 0.069
positive regulation of sodium ion transmembrane transport GO:1902307 9 0.069
regulation of growth GO:0040008 165 0.069
potassium ion transport GO:0006813 62 0.069
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.068
alcohol metabolic process GO:0006066 114 0.068
excretion GO:0007588 9 0.068
positive regulation of programmed cell death GO:0043068 249 0.067
positive regulation of protein kinase activity GO:0045860 190 0.067
positive regulation of developmental process GO:0051094 314 0.067
regulation of growth hormone secretion GO:0060123 3 0.067
cell differentiation in spinal cord GO:0021515 1 0.067
protein secretion GO:0009306 98 0.066
protein maturation GO:0051604 233 0.066
positive regulation of organelle organization GO:0010638 195 0.065
negative regulation of transmembrane transport GO:0034763 29 0.065
monocarboxylic acid transport GO:0015718 32 0.065
positive regulation of cell division GO:0051781 59 0.065
negative regulation of homeostatic process GO:0032845 59 0.065
negative regulation of dopamine receptor signaling pathway GO:0060160 1 0.064
actin filament based process GO:0030029 224 0.063
regulation of heart contraction GO:0008016 50 0.063
negative regulation of camp metabolic process GO:0030815 9 0.063
negative regulation of cellular component movement GO:0051271 106 0.063
regulation of body fluid levels GO:0050878 99 0.062
negative regulation of cell motility GO:2000146 104 0.062
phasic smooth muscle contraction GO:0014821 6 0.062
regulation of transmembrane transport GO:0034762 139 0.062
reactive oxygen species metabolic process GO:0072593 75 0.062
negative regulation of phosphorus metabolic process GO:0010563 267 0.061
diencephalon development GO:0021536 6 0.061
Human
multicellular organismal response to stress GO:0033555 1 0.061
somatostatin signaling pathway GO:0038170 1 0.061
cellular ion homeostasis GO:0006873 168 0.061
regulation of hormone secretion GO:0046883 57 0.061
negative regulation of developmental process GO:0051093 247 0.061
positive regulation of map kinase activity GO:0043406 80 0.061
regulation of transferase activity GO:0051338 355 0.060
regulation of reactive oxygen species metabolic process GO:2000377 41 0.060
regulation of homeostatic process GO:0032844 121 0.060
cell type specific apoptotic process GO:0097285 125 0.059
actin cytoskeleton organization GO:0030036 207 0.059
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 18 0.059
activation of mapk activity GO:0000187 45 0.058
regulation of calcium ion transmembrane transport GO:1903169 28 0.057
regulation of cytoskeleton organization GO:0051493 177 0.057
sensory perception GO:0007600 103 0.057
negative regulation of protein secretion GO:0050709 29 0.057
endocrine system development GO:0035270 26 0.057
growth hormone secretion GO:0030252 4 0.056
peptide secretion GO:0002790 51 0.055
phenol containing compound metabolic process GO:0018958 12 0.055
negative regulation of insulin secretion GO:0046676 9 0.055
negative regulation of apoptotic process GO:0043066 316 0.054
receptor mediated endocytosis GO:0006898 84 0.054
regulation of neurogenesis GO:0050767 82 0.054
enzyme linked receptor protein signaling pathway GO:0007167 303 0.054
regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway GO:0010578 5 0.053
regulation of voltage gated calcium channel activity GO:1901385 7 0.053
defense response GO:0006952 315 0.053
neuron differentiation GO:0030182 138 0.053
regulation of blood pressure GO:0008217 30 0.053
positive regulation of camp biosynthetic process GO:0030819 35 0.053
organ morphogenesis GO:0009887 147 0.052
behavioral response to cocaine GO:0048148 1 0.052
positive regulation of cytoskeleton organization GO:0051495 83 0.052
cellular response to oxygen levels GO:0071453 55 0.052
response to hypoxia GO:0001666 96 0.051
circadian regulation of gene expression GO:0032922 8 0.051
female gamete generation GO:0007292 2 0.051
nucleotide biosynthetic process GO:0009165 109 0.051
regulation of phosphatase activity GO:0010921 81 0.051
regulation of insulin secretion GO:0050796 33 0.051
single organism cellular localization GO:1902580 332 0.051
negative regulation of lyase activity GO:0051350 7 0.051
negative regulation of protein transport GO:0051224 75 0.051
regulation of cell cycle GO:0051726 393 0.051
fatty acid metabolic process GO:0006631 115 0.050
positive regulation of nucleotide metabolic process GO:0045981 230 0.050
regulation of response to external stimulus GO:0032101 222 0.050
regulation of cell migration GO:0030334 289 0.050
negative regulation of cell migration GO:0030336 102 0.049
anatomical structure formation involved in morphogenesis GO:0048646 284 0.049
regulation of cell division GO:0051302 116 0.049
positive regulation of cellular catabolic process GO:0031331 284 0.049
regulation of potassium ion transport GO:0043266 24 0.048
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.048
membrane hyperpolarization GO:0060081 1 0.048
blood circulation GO:0008015 113 0.048
regulation of endopeptidase activity GO:0052548 170 0.047
negative regulation of cytoskeleton organization GO:0051494 45 0.047
astrocyte differentiation GO:0048708 4 0.047
generation of neurons GO:0048699 152 0.047
cellular response to endogenous stimulus GO:0071495 336 0.047
regulation of peptide hormone secretion GO:0090276 41 0.047
organic hydroxy compound biosynthetic process GO:1901617 71 0.046
negative regulation of protein processing GO:0010955 142 0.046
carbohydrate metabolic process GO:0005975 207 0.046
covalent chromatin modification GO:0016569 254 0.046
post embryonic development GO:0009791 2 0.046
muscle contraction GO:0006936 73 0.046
immune response GO:0006955 307 0.045
multicellular organismal homeostasis GO:0048871 67 0.044
segmentation GO:0035282 4 0.044
positive regulation of cell cycle process GO:0090068 106 0.044
hindbrain development GO:0030902 3 0.044
neuron development GO:0048666 113 0.044
leukocyte activation GO:0045321 164 0.043
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.043
insulin secretion GO:0030073 39 0.043
dephosphorylation GO:0016311 209 0.043
oogenesis GO:0048477 2 0.043
response to iron ion GO:0010039 6 0.043
Rat
regulation of postsynaptic membrane potential GO:0060078 1 0.043
regulation of map kinase activity GO:0043405 108 0.042
heart process GO:0003015 62 0.042
regulation of cytokinesis GO:0032465 45 0.041
positive regulation of protein transport GO:0051222 135 0.041
prepulse inhibition GO:0060134 1 0.041
anion transmembrane transport GO:0098656 76 0.041
Human
exocytosis GO:0006887 71 0.041
vasodilation GO:0042311 4 0.041
regulation of peptide secretion GO:0002791 42 0.041
negative regulation of cell proliferation GO:0008285 228 0.040
response to nitrogen compound GO:1901698 184 0.040
Rat
negative regulation of calcium ion transport GO:0051926 19 0.040
monovalent inorganic cation homeostasis GO:0055067 37 0.039
hormone transport GO:0009914 68 0.039
actin filament organization GO:0007015 128 0.039
regulation of membrane potential GO:0042391 95 0.039
forebrain regionalization GO:0021871 3 0.039
negative regulation of proteolysis GO:0045861 132 0.038
adenylate cyclase inhibiting opioid receptor signaling pathway GO:0031635 1 0.038
positive regulation of actin filament polymerization GO:0030838 38 0.038
somatostatin receptor signaling pathway GO:0038169 1 0.038
reactive nitrogen species metabolic process GO:2001057 3 0.038
negative regulation of arp2 3 complex mediated actin nucleation GO:0034316 1 0.038
monocarboxylic acid metabolic process GO:0032787 185 0.037
response to organonitrogen compound GO:0010243 156 0.037
Rat
regulation of systemic arterial blood pressure GO:0003073 19 0.037
positive regulation of receptor mediated endocytosis GO:0048260 21 0.037

SLC6A3 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.092
nervous system disease DOID:863 431 0.092
sensory system disease DOID:0050155 203 0.061
eye and adnexa disease DOID:1492 150 0.042
eye disease DOID:5614 149 0.042
neurodegenerative disease DOID:1289 102 0.041