Homo sapiens

153 known processes

STAT1

signal transducer and activator of transcription 1, 91kDa

(Aliases: ISGF-3,DKFZp686B04100,STAT91)

STAT1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
defense response to virus GO:0051607 71 1.000
response to cytokine GO:0034097 232 1.000
interleukin 6 mediated signaling pathway GO:0070102 7 1.000
Human
defense response to other organism GO:0098542 129 1.000
positive regulation of cytokine production GO:0001819 167 0.999
defense response GO:0006952 315 0.998
cellular response to cytokine stimulus GO:0071345 181 0.997
immune effector process GO:0002252 159 0.994
immune response GO:0006955 307 0.992
viral life cycle GO:0019058 132 0.990
hematopoietic or lymphoid organ development GO:0048534 186 0.990
response to other organism GO:0051707 261 0.989
Mouse
positive regulation of interferon alpha production GO:0032727 11 0.986
positive regulation of interferon beta production GO:0032728 17 0.982
cytokine mediated signaling pathway GO:0019221 109 0.982
negative regulation of viral process GO:0048525 66 0.973
response to biotic stimulus GO:0009607 276 0.972
Mouse
positive regulation of innate immune response GO:0045089 79 0.970
cellular response to interferon gamma GO:0071346 24 0.966
regulation of cytokine production GO:0001817 232 0.953
response to nitrogen compound GO:1901698 184 0.953
Human Mouse
response to external biotic stimulus GO:0043207 261 0.950
Mouse
positive regulation of immune system process GO:0002684 283 0.950
response to interferon beta GO:0035456 11 0.943
positive regulation of type i interferon production GO:0032481 20 0.939
response to peptide GO:1901652 65 0.933
Human
regulation of interferon alpha production GO:0032647 11 0.905
regulation of innate immune response GO:0045088 97 0.878
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.878
Human
positive regulation of cell death GO:0010942 263 0.853
Mouse
ciliary neurotrophic factor mediated signaling pathway GO:0070120 5 0.850
response to oxygen containing compound GO:1901700 369 0.848
Human Mouse
cytokine production GO:0001816 247 0.847
regulation of immune response GO:0050776 201 0.842
cellular response to hormone stimulus GO:0032870 125 0.840
Human
response to interferon gamma GO:0034341 39 0.830
regulation of multi organism process GO:0043900 157 0.826
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.824
jak stat cascade involved in growth hormone signaling pathway GO:0060397 2 0.820
Human
viral genome replication GO:0019079 50 0.818
cytoplasmic transport GO:0016482 379 0.807
Human
innate immune response GO:0045087 178 0.802
response to molecule of bacterial origin GO:0002237 82 0.799
Mouse
cellular response to growth hormone stimulus GO:0071378 10 0.795
Human
regulation of interleukin 6 mediated signaling pathway GO:0070103 3 0.784
response to virus GO:0009615 126 0.782
regulation of defense response to virus by host GO:0050691 22 0.775
regulation of cellular ketone metabolic process GO:0010565 50 0.758
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.756
cellular response to endogenous stimulus GO:0071495 336 0.752
Human
multi organism cellular process GO:0044764 156 0.730
neuron projection regeneration GO:0031102 1 0.724
response to organonitrogen compound GO:0010243 156 0.723
Human
nuclear transport GO:0051169 179 0.719
Human
regulation of binding GO:0051098 111 0.706
immune response regulating signaling pathway GO:0002764 97 0.693
immune system development GO:0002520 195 0.681
negative regulation of cytokine mediated signaling pathway GO:0001960 22 0.681
negative regulation of multi organism process GO:0043901 92 0.679
cellular response to interferon beta GO:0035458 6 0.662
intracellular receptor signaling pathway GO:0030522 104 0.646
Human
regulation of defense response to virus GO:0050688 33 0.639
interleukin 2 mediated signaling pathway GO:0038110 3 0.639
positive regulation of defense response GO:0031349 87 0.638
response to hormone GO:0009725 175 0.617
Human
regulation of cell cycle GO:0051726 393 0.611
regulation of defense response GO:0031347 154 0.588
regulation of intracellular transport GO:0032386 195 0.585
activation of immune response GO:0002253 114 0.581
response to interleukin 4 GO:0070670 7 0.581
Human
rig i signaling pathway GO:0039529 7 0.557
protein targeting to nucleus GO:0044744 104 0.557
Human
positive regulation of programmed cell death GO:0043068 249 0.551
Mouse
establishment of protein localization to organelle GO:0072594 172 0.537
Human
response to organic cyclic compound GO:0014070 204 0.507
Human Mouse
interferon beta production GO:0032608 23 0.503
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.496
cell cycle arrest GO:0007050 71 0.490
regulation of response to biotic stimulus GO:0002831 55 0.488
cellular response to dna damage stimulus GO:0006974 379 0.481
interleukin 27 mediated signaling pathway GO:0070106 1 0.476
regulation of response to external stimulus GO:0032101 222 0.473
regulation of nucleocytoplasmic transport GO:0046822 98 0.445
nucleocytoplasmic transport GO:0006913 176 0.432
Human
regulation of intracellular protein transport GO:0033157 123 0.432
immune response activating signal transduction GO:0002757 90 0.430
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.430
cellular response to organic cyclic compound GO:0071407 127 0.421
oncostatin m mediated signaling pathway GO:0038165 3 0.421
negative regulation of developmental process GO:0051093 247 0.405
regulation of angiogenesis GO:0045765 92 0.400
cellular response to lipid GO:0071396 127 0.397
Mouse
interspecies interaction between organisms GO:0044419 156 0.393
regulation of type i interferon production GO:0032479 26 0.389
positive regulation of multi organism process GO:0043902 56 0.386
epithelium development GO:0060429 227 0.383
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 18 0.376
jak stat cascade GO:0007259 46 0.374
interferon gamma mediated signaling pathway GO:0060333 7 0.367
protein targeting GO:0006605 187 0.359
Human
cellular response to organonitrogen compound GO:0071417 124 0.358
Human
protein ubiquitination GO:0016567 314 0.350
chromatin organization GO:0006325 351 0.347
cellular response to interleukin 6 GO:0071354 14 0.327
Human
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 16 0.326
protein localization to nucleus GO:0034504 136 0.316
Human
regulation of transferase activity GO:0051338 355 0.312
negative regulation of protein metabolic process GO:0051248 391 0.303
gene silencing by mirna GO:0035195 23 0.299
negative regulation of cell differentiation GO:0045596 171 0.294
negative regulation of cell proliferation GO:0008285 228 0.286
regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039531 7 0.286
regulation of cellular component biogenesis GO:0044087 281 0.284
erythrocyte differentiation GO:0030218 28 0.281
cellular response to interleukin 12 GO:0071349 3 0.279
protein import into nucleus GO:0006606 104 0.277
Human
positive regulation of developmental process GO:0051094 314 0.273
regulation of protein transport GO:0051223 213 0.272
positive regulation of rig i signaling pathway GO:1900246 4 0.259
negative regulation of defense response GO:0031348 47 0.250
hemopoiesis GO:0030097 180 0.249
cytoplasmic pattern recognition receptor signaling pathway in response to virus GO:0039528 8 0.246
type i interferon production GO:0032606 27 0.244
single organism cellular localization GO:1902580 332 0.241
Human
response to bacterium GO:0009617 144 0.237
Mouse
cellular response to oxygen containing compound GO:1901701 276 0.236
Human Mouse
leukocyte differentiation GO:0002521 98 0.236
regulation of cytoplasmic transport GO:1903649 149 0.232
interferon alpha production GO:0032607 11 0.227
negative regulation of interleukin 6 mediated signaling pathway GO:0070104 2 0.226
negative regulation of apoptotic process GO:0043066 316 0.226
regulation of viral genome replication GO:0045069 48 0.225
tyrosine phosphorylation of stat3 protein GO:0042503 20 0.225
negative regulation of intracellular signal transduction GO:1902532 183 0.221
response to steroid hormone GO:0048545 80 0.221
Human
response to peptide hormone GO:0043434 61 0.219
Human
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.218
regulation of interferon beta production GO:0032648 22 0.216
positive regulation of apoptotic process GO:0043065 246 0.211
Mouse
regulation of apoptotic signaling pathway GO:2001233 175 0.208
angiogenesis GO:0001525 147 0.205
cellular response to nitrogen compound GO:1901699 144 0.198
Human
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001269 1 0.196
protein modification by small protein conjugation GO:0032446 342 0.186
cellular macromolecular complex assembly GO:0034622 324 0.182
positive regulation of proteolysis GO:0045862 142 0.180
Mouse
positive regulation of apoptotic signaling pathway GO:2001235 70 0.180
regulation of cytokine mediated signaling pathway GO:0001959 41 0.171
regulation of rig i signaling pathway GO:0039535 6 0.171
intracellular protein transport GO:0006886 270 0.167
Human
negative regulation of cellular protein metabolic process GO:0032269 353 0.164
negative regulation of protein phosphorylation GO:0001933 140 0.163
axon regeneration GO:0031103 1 0.162
activation of innate immune response GO:0002218 55 0.157
associative learning GO:0008306 1 0.153
cellular amino acid metabolic process GO:0006520 116 0.153
response to estrogen GO:0043627 47 0.151
Human
chromatin modification GO:0016568 298 0.150
type i interferon signaling pathway GO:0060337 11 0.148
Mouse
negative regulation of catalytic activity GO:0043086 335 0.146
positive regulation of hydrolase activity GO:0051345 331 0.142
Mouse
positive regulation of intracellular protein transport GO:0090316 76 0.139
tyrosine phosphorylation of stat protein GO:0007260 33 0.138
enzyme linked receptor protein signaling pathway GO:0007167 303 0.137
Human
cellular response to abiotic stimulus GO:0071214 117 0.137
regulation of establishment of protein localization GO:0070201 242 0.136
modification dependent protein catabolic process GO:0019941 209 0.135
cellular response to type i interferon GO:0071357 12 0.134
Mouse
modification dependent macromolecule catabolic process GO:0043632 212 0.133
negative regulation of programmed cell death GO:0043069 321 0.132
negative regulation of phosphorylation GO:0042326 174 0.131
regulation of cell migration GO:0030334 289 0.130
ameboidal type cell migration GO:0001667 135 0.128
negative regulation of immune system process GO:0002683 136 0.125
regulation of dna binding GO:0051101 37 0.124
tumor necrosis factor mediated signaling pathway GO:0033209 27 0.124
mitochondrion organization GO:0007005 156 0.120
positive regulation of cellular amine metabolic process GO:0033240 7 0.116
negative regulation of cell death GO:0060548 345 0.115
leukocyte proliferation GO:0070661 74 0.115
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.112
Mouse
histone modification GO:0016570 251 0.111
regulation of tyrosine phosphorylation of stat protein GO:0042509 30 0.111
protein polyubiquitination GO:0000209 110 0.111
negative regulation of phosphate metabolic process GO:0045936 267 0.109
response to tumor necrosis factor GO:0034612 76 0.107
negative regulation of protein modification process GO:0031400 200 0.107
regulation of kinase activity GO:0043549 314 0.102
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.102
negative regulation of innate immune response GO:0045824 18 0.101
regulation of gene expression epigenetic GO:0040029 73 0.100
regulation of protein localization to nucleus GO:1900180 85 0.100
nuclear import GO:0051170 106 0.099
Human
regulation of cellular amino acid metabolic process GO:0006521 6 0.099
negative regulation of multicellular organismal process GO:0051241 317 0.097
myeloid cell differentiation GO:0030099 117 0.094
positive regulation of cell differentiation GO:0045597 211 0.093
i kappab kinase nf kappab signaling GO:0007249 166 0.090
rna interference GO:0016246 4 0.090
secretion GO:0046903 254 0.089
dsrna fragmentation GO:0031050 13 0.088
vasculature development GO:0001944 181 0.086
protein localization to organelle GO:0033365 280 0.085
Human
regulation of protein import into nucleus GO:0042306 78 0.085
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.082
intrinsic apoptotic signaling pathway GO:0097193 127 0.082
negative regulation of transport GO:0051051 176 0.080
response to axon injury GO:0048678 1 0.080
purine nucleoside monophosphate metabolic process GO:0009126 186 0.080
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.079
Mouse
regulation of locomotion GO:0040012 329 0.079
regulation of cysteine type endopeptidase activity GO:2000116 127 0.078
Mouse
rna processing GO:0006396 255 0.074
positive regulation of protein complex assembly GO:0031334 86 0.074
protein processing GO:0016485 226 0.072
Mouse
response to thyroid hormone GO:0097066 9 0.071
positive regulation of response to external stimulus GO:0032103 88 0.071
astrocyte differentiation GO:0048708 4 0.071
positive regulation of protein localization to nucleus GO:1900182 48 0.070
negative regulation of hydrolase activity GO:0051346 182 0.070
apoptotic signaling pathway GO:0097190 268 0.070
ubiquitin dependent protein catabolic process GO:0006511 206 0.070
negative regulation of response to cytokine stimulus GO:0060761 25 0.068
regulation of peptidase activity GO:0052547 180 0.067
Mouse
interleukin 12 mediated signaling pathway GO:0035722 3 0.067
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.066
Mouse
positive regulation of protein transport GO:0051222 135 0.065
epithelial cell differentiation GO:0030855 141 0.064
response to drug GO:0042493 81 0.064
regulation of cell differentiation GO:0045595 393 0.063
regulation of proteolysis GO:0030162 293 0.063
Mouse
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 21 0.061
protein import GO:0017038 130 0.060
Human
t cell activation GO:0042110 99 0.060
circulatory system process GO:0003013 113 0.060
cellular response to glucocorticoid stimulus GO:0071385 4 0.059
regulation of fas signaling pathway GO:1902044 2 0.058
protein maturation GO:0051604 233 0.058
Mouse
regulation of mononuclear cell proliferation GO:0032944 65 0.058
regulation of cell development GO:0060284 161 0.057
covalent chromatin modification GO:0016569 254 0.057
activation of cysteine type endopeptidase activity GO:0097202 57 0.056
Mouse
positive regulation of interferon gamma production GO:0032729 26 0.055
response to abiotic stimulus GO:0009628 336 0.055
osteoblast differentiation GO:0001649 92 0.054
atp metabolic process GO:0046034 176 0.053
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.053
Mouse
regulation of mapk cascade GO:0043408 262 0.053
production of mirnas involved in gene silencing by mirna GO:0035196 12 0.052
negative regulation of kinase activity GO:0033673 106 0.052
lymphocyte differentiation GO:0030098 35 0.052
regeneration GO:0031099 4 0.051
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.051
cytokine biosynthetic process GO:0042089 37 0.050
mapk cascade GO:0000165 288 0.050
regulation of interferon gamma production GO:0032649 36 0.049
positive regulation of immune response GO:0050778 159 0.049
positive regulation of intracellular transport GO:0032388 104 0.049
regulation of tyrosine phosphorylation of stat1 protein GO:0042510 11 0.049
regulation of protein localization GO:0032880 296 0.049
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.049
myeloid cell homeostasis GO:0002262 34 0.048
negative regulation of viral genome replication GO:0045071 35 0.048
chemical homeostasis GO:0048878 306 0.047
renal tubule development GO:0061326 19 0.047
glycosylation GO:0070085 71 0.047
endothelial cell proliferation GO:0001935 65 0.046
cellular macromolecule catabolic process GO:0044265 380 0.045
erythrocyte homeostasis GO:0034101 31 0.044
positive regulation of cellular component organization GO:0051130 376 0.044
t cell differentiation GO:0030217 29 0.044
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 28 0.043
interferon gamma production GO:0032609 39 0.042
negative regulation of tyrosine phosphorylation of stat3 protein GO:0042518 2 0.042
response to radiation GO:0009314 151 0.041
positive regulation of interleukin 13 production GO:0032736 4 0.041
positive regulation of locomotion GO:0040017 186 0.041
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.040
regulation of protein complex assembly GO:0043254 147 0.040
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.040
type i interferon biosynthetic process GO:0045351 4 0.039
epithelial cell proliferation GO:0050673 128 0.039
dna damage response signal transduction by p53 class mediator GO:0030330 44 0.039
negative regulation of proteolysis GO:0045861 132 0.039
regulation of interleukin 1 production GO:0032652 21 0.038
positive regulation of cell proliferation GO:0008284 301 0.038
negative regulation of transferase activity GO:0051348 124 0.038
viral transcription GO:0019083 35 0.038
regulation of anatomical structure morphogenesis GO:0022603 286 0.038
response to lipid GO:0033993 206 0.038
Human Mouse
regulation of secretion by cell GO:1903530 177 0.037
cell activation GO:0001775 213 0.037
positive regulation of protein kinase activity GO:0045860 190 0.037
positive regulation of myeloid cell differentiation GO:0045639 39 0.037
response to peptidoglycan GO:0032494 3 0.036
cellular response to molecule of bacterial origin GO:0071219 62 0.035
Mouse
cellular response to virus GO:0098586 9 0.035
regulation of cell motility GO:2000145 299 0.034
mitotic cell cycle GO:0000278 326 0.034
ncrna metabolic process GO:0034660 108 0.034
cell cycle checkpoint GO:0000075 117 0.034
positive regulation of secretion GO:0051047 116 0.033
positive regulation of cellular component biogenesis GO:0044089 158 0.032
negative regulation of cell cycle GO:0045786 193 0.032
negative regulation of heart contraction GO:0045822 3 0.032
positive regulation of protein phosphorylation GO:0001934 313 0.032
cellular response to interleukin 4 GO:0071353 7 0.032
Human
regulation of protein import into nucleus translocation GO:0033158 10 0.032
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.031
protein catabolic process GO:0030163 325 0.030
regulation of dna metabolic process GO:0051052 153 0.030
regulation of fibroblast proliferation GO:0048145 32 0.030
positive regulation of gliogenesis GO:0014015 4 0.030
positive regulation of cell activation GO:0050867 81 0.030
negative regulation of binding GO:0051100 57 0.029
acylglycerol metabolic process GO:0006639 27 0.029
cellular response to lipopolysaccharide GO:0071222 57 0.029
Mouse
sensory organ development GO:0007423 52 0.029
regulation of response to cytokine stimulus GO:0060759 46 0.029
positive regulation of endopeptidase activity GO:0010950 84 0.029
Mouse
regulation of cell activation GO:0050865 125 0.028
response to ionizing radiation GO:0010212 65 0.028
positive regulation of cytoplasmic transport GO:1903651 82 0.028
response to insulin GO:0032868 45 0.028
innate immune response activating signal transduction GO:0002758 48 0.027
protein export from nucleus GO:0006611 29 0.027
negative regulation of blood circulation GO:1903523 4 0.027
double strand break repair GO:0006302 101 0.026
negative regulation of striated muscle cell apoptotic process GO:0010664 2 0.026
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.026
blood vessel development GO:0001568 172 0.026
negative regulation of protein kinase activity GO:0006469 98 0.026
regulation of protein ubiquitination GO:0031396 95 0.025
regulation of viral process GO:0050792 103 0.025
single organism nuclear import GO:1902593 104 0.025
Human
myeloid leukocyte differentiation GO:0002573 60 0.025
cellular response to tumor necrosis factor GO:0071356 63 0.025
extrinsic apoptotic signaling pathway GO:0097191 119 0.025
positive regulation of peptidase activity GO:0010952 88 0.025
Mouse
cellular response to peptide hormone stimulus GO:0071375 56 0.024
Human
cell type specific apoptotic process GO:0097285 125 0.024
positive regulation of phosphorylation GO:0042327 394 0.024
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.024
blood circulation GO:0008015 113 0.024
negative regulation of endopeptidase activity GO:0010951 84 0.024
negative regulation of cytosolic calcium ion concentration GO:0051481 1 0.023
fas signaling pathway GO:0036337 3 0.023
lymphocyte proliferation GO:0046651 70 0.023
nitrogen compound transport GO:0071705 191 0.023
negative regulation of vasculature development GO:1901343 43 0.023
posttranscriptional regulation of gene expression GO:0010608 213 0.022
cellular response to oxidative stress GO:0034599 85 0.022
vesicle mediated transport GO:0016192 371 0.022
divalent metal ion transport GO:0070838 152 0.022
positive regulation of jak stat cascade GO:0046427 35 0.022
mesenchyme development GO:0060485 59 0.022
response to interleukin 13 GO:0035962 4 0.022
peripheral nervous system development GO:0007422 2 0.022
negative regulation of protein modification by small protein conjugation or removal GO:1903321 41 0.022
pattern recognition receptor signaling pathway GO:0002221 48 0.021
negative regulation of dna binding GO:0043392 18 0.021
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.021
cellular cation homeostasis GO:0030003 163 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.021
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.021
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.020
positive regulation of osteoblast differentiation GO:0045669 23 0.020
cellular protein catabolic process GO:0044257 261 0.020
nucleoside triphosphate metabolic process GO:0009141 422 0.020
central nervous system development GO:0007417 123 0.020
negative regulation of type i interferon mediated signaling pathway GO:0060339 4 0.020
regulation of cell projection organization GO:0031344 107 0.020
atp catabolic process GO:0006200 157 0.020
zymogen activation GO:0031638 70 0.020
Mouse
response to mechanical stimulus GO:0009612 51 0.020
monocyte differentiation GO:0030224 15 0.020
carbohydrate metabolic process GO:0005975 207 0.020
negative regulation of defense response to virus by host GO:0050689 4 0.019
ribonucleoprotein complex biogenesis GO:0022613 116 0.019
regulation of growth GO:0040008 165 0.019
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.019
cellular protein complex assembly GO:0043623 188 0.019
neurological system process GO:0050877 163 0.019
negative regulation of protein ubiquitination GO:0031397 35 0.019
positive regulation of secretion by cell GO:1903532 108 0.019
regulation of tumor necrosis factor production GO:0032680 43 0.019
peptide secretion GO:0002790 51 0.019
regulation of t cell proliferation GO:0042129 42 0.019
interleukin 4 mediated signaling pathway GO:0035771 3 0.018
Human
cellular response to peptide GO:1901653 59 0.018
Human
homeostasis of number of cells GO:0048872 40 0.018
positive regulation of t cell activation GO:0050870 54 0.018
negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039532 3 0.018
apoptotic mitochondrial changes GO:0008637 57 0.018
cellular response to external stimulus GO:0071496 111 0.018
protein autophosphorylation GO:0046777 123 0.018
regulation of neuron migration GO:2001222 3 0.018
cellular amine metabolic process GO:0044106 41 0.018
regulation of cellular component movement GO:0051270 334 0.018
single organism carbohydrate metabolic process GO:0044723 193 0.018
signal transduction by phosphorylation GO:0023014 297 0.018
response to extracellular stimulus GO:0009991 85 0.017
purine nucleoside triphosphate metabolic process GO:0009144 412 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.017
epithelial cell migration GO:0010631 119 0.017
neuron differentiation GO:0030182 138 0.017
cellular ion homeostasis GO:0006873 168 0.017
peptidyl tyrosine phosphorylation GO:0018108 170 0.017
tissue migration GO:0090130 119 0.017
tyrosine phosphorylation of stat5 protein GO:0042506 13 0.017
mammary gland development GO:0030879 17 0.016
protein glycosylation GO:0006486 62 0.016
regulation of immune effector process GO:0002697 91 0.016
regulation of neurogenesis GO:0050767 82 0.016
adaptive immune response GO:0002250 49 0.016
glucose homeostasis GO:0042593 31 0.016
lymphocyte activation GO:0046649 133 0.016
embryo development GO:0009790 123 0.016
compound eye development GO:0048749 1 0.016
response to oxidative stress GO:0006979 121 0.016
growth hormone receptor signaling pathway GO:0060396 10 0.016
Human
regulation of endopeptidase activity GO:0052548 170 0.016
Mouse
single organism membrane organization GO:0044802 268 0.015
positive regulation of organelle organization GO:0010638 195 0.015
negative regulation of cytokine production GO:0001818 82 0.015
regulation of heart contraction GO:0008016 50 0.015
generation of neurons GO:0048699 152 0.015
tyrosine phosphorylation of stat1 protein GO:0042508 11 0.015
regulation of secretion GO:0051046 194 0.015
cytokine metabolic process GO:0042107 38 0.015
organophosphate biosynthetic process GO:0090407 163 0.015
positive regulation of mononuclear cell proliferation GO:0032946 47 0.015
regulation of glial cell differentiation GO:0045685 3 0.015
arp2 3 complex mediated actin nucleation GO:0034314 17 0.014
multi organism transport GO:0044766 14 0.014
metal ion homeostasis GO:0055065 169 0.014
glycerolipid biosynthetic process GO:0045017 51 0.014
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.014
ncrna processing GO:0034470 83 0.014
peptidyl tyrosine modification GO:0018212 170 0.014
blastoderm segmentation GO:0007350 2 0.014
microtubule based process GO:0007017 210 0.013
regulation of mda 5 signaling pathway GO:0039533 4 0.013
positive regulation of nervous system development GO:0051962 54 0.013
interleukin 2 secretion GO:0070970 3 0.013
pyruvate metabolic process GO:0006090 26 0.013
positive regulation of cell development GO:0010720 92 0.013
positive regulation of immune effector process GO:0002699 40 0.013
actin mediated cell contraction GO:0070252 12 0.013
dna repair GO:0006281 198 0.013
regulation of endothelial cell proliferation GO:0001936 56 0.013
cellular divalent inorganic cation homeostasis GO:0072503 128 0.013
axon development GO:0061564 34 0.013
locomotory behavior GO:0007626 1 0.013
response to estradiol GO:0032355 23 0.013
Human
positive regulation of protein import into nucleus GO:0042307 46 0.013
ribonucleoprotein complex assembly GO:0022618 78 0.013
regulation of insulin secretion GO:0050796 33 0.013
gland development GO:0048732 48 0.012
regulation of lymphocyte proliferation GO:0050670 64 0.012
leukocyte activation GO:0045321 164 0.012
regulation of t cell activation GO:0050863 77 0.012
purine containing compound catabolic process GO:0072523 411 0.012
divalent inorganic cation transport GO:0072511 158 0.012
stem cell maintenance GO:0019827 19 0.012
retrograde transport endosome to golgi GO:0042147 45 0.012
cellular response to mechanical stimulus GO:0071260 39 0.012
posttranscriptional gene silencing GO:0016441 25 0.012
regulation of protein targeting GO:1903533 91 0.012
tissue morphogenesis GO:0048729 96 0.012
regulation of adaptive immune response GO:0002819 33 0.011
positive regulation of leukocyte activation GO:0002696 80 0.011
actin filament based movement GO:0030048 17 0.011
protein oligomerization GO:0051259 173 0.011
cellular homeostasis GO:0019725 196 0.011
epithelium migration GO:0090132 119 0.011
long term memory GO:0007616 2 0.011
cellular response to interferon alpha GO:0035457 4 0.011

STAT1 disease predictions

Disease DO term ID Size Probability Func Analog Org
myeloma DOID:0070004 7 0.120
immune system cancer DOID:0060083 36 0.120
hematologic cancer DOID:2531 36 0.120
cancer DOID:162 167 0.120
disease of cellular proliferation DOID:14566 174 0.120
organ system cancer DOID:0050686 164 0.120
bone marrow cancer DOID:4960 10 0.120
disease of metabolism DOID:0014667 295 0.051
acquired metabolic disease DOID:0060158 58 0.051
aicardi goutieres syndrome DOID:0050629 7 0.040
myeloid leukemia DOID:8692 18 0.024
acute myeloid leukemia DOID:9119 17 0.024
leukemia DOID:1240 21 0.024
carbohydrate metabolism disease DOID:0050013 32 0.018
immune system disease DOID:2914 155 0.016
Human
hematopoietic system disease DOID:74 100 0.016