IMP

Process View

Homo sapiens

11 genes annotated in human

Multi-species View

regulation of interferon alpha production

GO:0032647

Any process that modulates the frequency, rate, or extent of interferon-alpha production.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of interferon alpha production"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of interferon alpha production" (in gray)

Name	Description	Probability	Func Analog Organism
DDX58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.948
STAT1	signal transducer and activator of transcription 1, 91kDa	0.905
CYLD	cylindromatosis (turban tumor syndrome)	0.884
MYD88	myeloid differentiation primary response gene (88)	0.868
STAT2	signal transducer and activator of transcription 2, 113kDa	0.823
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.626	Human
TBK1	TANK-binding kinase 1	0.558
IRF7	interferon regulatory factor 7	0.518
IRF3	interferon regulatory factor 3	0.470	Human Mouse
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.300
EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	0.218
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.210	Human
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.191
IRF1	interferon regulatory factor 1	0.171	Human
IRAK1	interleukin-1 receptor-associated kinase 1	0.164
TRIM21	tripartite motif containing 21	0.161
PARP12	poly (ADP-ribose) polymerase family, member 12	0.138	Human
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.133
ZC3HAV1	zinc finger CCCH-type, antiviral 1	0.099
NLRC5	NLR family, CARD domain containing 5	0.096
STAT6	signal transducer and activator of transcription 6, interleukin-4 induced	0.087
TRIM25	tripartite motif containing 25	0.069
IRF9	interferon regulatory factor 9	0.067	Human
MAP3K14	mitogen-activated protein kinase kinase kinase 14	0.057
CALCOCO2	calcium binding and coiled-coil domain 2	0.043
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.041
AZI2	5-azacytidine induced 2	0.040
PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator	0.038
ADAR	adenosine deaminase, RNA-specific	0.038
SP110	SP110 nuclear body protein	0.037
IFNAR2	interferon (alpha, beta and omega) receptor 2	0.036
CREBBP	CREB binding protein	0.035
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.030
MAVS	mitochondrial antiviral signaling protein	0.029
PPP2R2B	protein phosphatase 2, regulatory subunit B, beta	0.028
EIF2C2	eukaryotic translation initiation factor 2C, 2	0.028
TANK	TRAF family member-associated NFKB activator	0.027
PIAS4	protein inhibitor of activated STAT, 4	0.026
C19orf66	chromosome 19 open reading frame 66	0.026
IFIH1	interferon induced with helicase C domain 1	0.024
TLR2	toll-like receptor 2	0.024
IFI35	interferon-induced protein 35	0.021
IRF2	interferon regulatory factor 2	0.020	Human
OAS2	2'-5'-oligoadenylate synthetase 2, 69/71kDa	0.020
IFNAR1	interferon (alpha, beta and omega) receptor 1	0.018
ZNFX1	zinc finger, NFX1-type containing 1	0.018
TRANK1	tetratricopeptide repeat and ankyrin repeat containing 1	0.018
ISG20	interferon stimulated exonuclease gene 20kDa	0.017
IRF2BP2	interferon regulatory factor 2 binding protein 2	0.017
KIAA1274	KIAA1274	0.016
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.016
TLR4	toll-like receptor 4	0.015	Human Mouse
TICAM2	toll-like receptor adaptor molecule 2	0.015
KAT2B	K(lysine) acetyltransferase 2B	0.014
NMI	N-myc (and STAT) interactor	0.014
PPP3CB	protein phosphatase 3, catalytic subunit, beta isozyme	0.014
OPTN	optineurin	0.014
IRF8	interferon regulatory factor 8	0.013	Human
TNFSF10	tumor necrosis factor (ligand) superfamily, member 10	0.012
TMEM140	transmembrane protein 140	0.012
PRKD2	protein kinase D2	0.012
OAS3	2'-5'-oligoadenylate synthetase 3, 100kDa	0.011
CLTC	clathrin, heavy chain (Hc)	0.011
DTX3L	deltex 3-like (Drosophila)	0.011
TRAF2	TNF receptor-associated factor 2	0.011
MAFB	v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)	0.011
JAK2	Janus kinase 2	0.011
FKBP5	FK506 binding protein 5	0.011
TLR1	toll-like receptor 1	0.010	Human
EIF2C1	eukaryotic translation initiation factor 2C, 1	0.010