IMP

Process View

Homo sapiens

22 genes annotated in human

Multi-species View

regulation of interferon beta production

GO:0032648

Any process that modulates the frequency, rate, or extent of interferon-beta production.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of interferon beta production"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of interferon beta production" (in gray)

Name	Description	Probability	Func Analog Organism
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.994	Human
MYD88	myeloid differentiation primary response gene (88)	0.975
LILRA6	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6	0.964
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.930
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.910
IRF7	interferon regulatory factor 7	0.704	Human
EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	0.696
TANK	TRAF family member-associated NFKB activator	0.620
MAVS	mitochondrial antiviral signaling protein	0.582
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.580
STAT2	signal transducer and activator of transcription 2, 113kDa	0.578
DDX58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.526
PILRA	paired immunoglobin-like type 2 receptor alpha	0.521
CYLD	cylindromatosis (turban tumor syndrome)	0.442
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.340
MAP3K14	mitogen-activated protein kinase kinase kinase 14	0.327
KAT2B	K(lysine) acetyltransferase 2B	0.286
TBK1	TANK-binding kinase 1	0.264
BIRC3	baculoviral IAP repeat containing 3	0.233
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.224	Human
TRAF2	TNF receptor-associated factor 2	0.221
TICAM2	toll-like receptor adaptor molecule 2	0.218
STAT1	signal transducer and activator of transcription 1, 91kDa	0.216
NLRC4	NLR family, CARD domain containing 4	0.195
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.188
CHUK	conserved helix-loop-helix ubiquitous kinase	0.184	Human
HK3	hexokinase 3 (white cell)	0.178
NLRP3	NLR family, pyrin domain containing 3	0.167
PRPF4B	PRP4 pre-mRNA processing factor 4 homolog B (yeast)	0.158
IRF3	interferon regulatory factor 3	0.154	Human Mouse
PTAFR	platelet-activating factor receptor	0.145
LILRB3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.138	Human
SP110	SP110 nuclear body protein	0.125
TRAF6	TNF receptor-associated factor 6	0.116
TRIM21	tripartite motif containing 21	0.114
IRAK1	interleukin-1 receptor-associated kinase 1	0.102
LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	0.100	Human
ZC3HAV1	zinc finger CCCH-type, antiviral 1	0.098
NLRC5	NLR family, CARD domain containing 5	0.098
ADAR	adenosine deaminase, RNA-specific	0.096
TRAF3	TNF receptor-associated factor 3	0.093	Mouse
POLR1C	polymerase (RNA) I polypeptide C, 30kDa	0.089
SIGLEC7	sialic acid binding Ig-like lectin 7	0.089
PIAS4	protein inhibitor of activated STAT, 4	0.088
LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2	0.088
LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	0.082	Human
TRIM25	tripartite motif containing 25	0.082
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.074
MEFV	Mediterranean fever	0.071
TRAF1	TNF receptor-associated factor 1	0.065
MX2	myxovirus (influenza virus) resistance 2 (mouse)	0.061
IRF1	interferon regulatory factor 1	0.060
TLR2	toll-like receptor 2	0.053
OAS3	2'-5'-oligoadenylate synthetase 3, 100kDa	0.051
IFI35	interferon-induced protein 35	0.049
SPI1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	0.049
IFNAR2	interferon (alpha, beta and omega) receptor 2	0.048
OAS2	2'-5'-oligoadenylate synthetase 2, 69/71kDa	0.046
ZNFX1	zinc finger, NFX1-type containing 1	0.045
NOD2	nucleotide-binding oligomerization domain containing 2	0.045
OASL	2'-5'-oligoadenylate synthetase-like	0.045
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.043	Mouse
EIF2C1	eukaryotic translation initiation factor 2C, 1	0.042
CD33	CD33 molecule	0.041
POLR3H	polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)	0.040
STAT6	signal transducer and activator of transcription 6, interleukin-4 induced	0.039
IRF9	interferon regulatory factor 9	0.037	Human
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.036
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.035
CREBBP	CREB binding protein	0.035
CCR1	chemokine (C-C motif) receptor 1	0.033
IRAK4	interleukin-1 receptor-associated kinase 4	0.033
PARP12	poly (ADP-ribose) polymerase family, member 12	0.033	Human
SGTA	small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha	0.032
TMEM173	transmembrane protein 173	0.032
IRAK2	interleukin-1 receptor-associated kinase 2	0.031
VNN2	vanin 2	0.030
CYTH4	cytohesin 4	0.030
HLA-G	major histocompatibility complex, class I, G	0.030
CALCOCO2	calcium binding and coiled-coil domain 2	0.029
IRF2BP2	interferon regulatory factor 2 binding protein 2	0.028
MR1	major histocompatibility complex, class I-related	0.027
TRAFD1	TRAF-type zinc finger domain containing 1	0.026
IRAK3	interleukin-1 receptor-associated kinase 3	0.026
POLR3E	polymerase (RNA) III (DNA directed) polypeptide E (80kD)	0.025
TRANK1	tetratricopeptide repeat and ankyrin repeat containing 1	0.024
TYMP	thymidine phosphorylase	0.023
TLR4	toll-like receptor 4	0.023	Human Mouse
SIRPB1	signal-regulatory protein beta 1	0.023
IRF2	interferon regulatory factor 2	0.023	Human
IFNAR1	interferon (alpha, beta and omega) receptor 1	0.022
TLR8	toll-like receptor 8	0.022
TMEM140	transmembrane protein 140	0.022
PPP3CB	protein phosphatase 3, catalytic subunit, beta isozyme	0.021
C19orf66	chromosome 19 open reading frame 66	0.021
PPP2R2B	protein phosphatase 2, regulatory subunit B, beta	0.021
APOL6	apolipoprotein L, 6	0.020
ISG20	interferon stimulated exonuclease gene 20kDa	0.020
CD180	CD180 molecule	0.019	Human
FKBP5	FK506 binding protein 5	0.019
IFIH1	interferon induced with helicase C domain 1	0.018
CD28	CD28 molecule	0.018
PHF11	PHD finger protein 11	0.018
SPOP	speckle-type POZ protein	0.018
AZI2	5-azacytidine induced 2	0.018
TRIM38	tripartite motif containing 38	0.018	Mouse
TLR6	toll-like receptor 6	0.018	Human
PRKD2	protein kinase D2	0.018
TNIP1	TNFAIP3 interacting protein 1	0.018
OPTN	optineurin	0.017
CR1	complement component (3b/4b) receptor 1 (Knops blood group)	0.017
STAP2	signal transducing adaptor family member 2	0.017
KMO	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.017
IGSF6	immunoglobulin superfamily, member 6	0.017
SIGLEC9	sialic acid binding Ig-like lectin 9	0.017
TARBP2	TAR (HIV-1) RNA binding protein 2	0.017
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.017
BATF	basic leucine zipper transcription factor, ATF-like	0.017
LRIF1	ligand dependent nuclear receptor interacting factor 1	0.016
CD300C	CD300c molecule	0.016
CD40	CD40 molecule, TNF receptor superfamily member 5	0.016
CD86	CD86 molecule	0.016
AOAH	acyloxyacyl hydrolase (neutrophil)	0.016
MX1	myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)	0.016
OAS1	2',5'-oligoadenylate synthetase 1, 40/46kDa	0.015
FCGR2B	Fc fragment of IgG, low affinity IIb, receptor (CD32)	0.015
HERC5	hect domain and RLD 5	0.015
POLR3D	polymerase (RNA) III (DNA directed) polypeptide D, 44kDa	0.015
RIPK3	receptor-interacting serine-threonine kinase 3	0.015
SLAMF7	SLAM family member 7	0.015
ATG7	ATG7 autophagy related 7 homolog (S. cerevisiae)	0.015
LILRB4	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4	0.015	Human
TREM1	triggering receptor expressed on myeloid cells 1	0.014
USP18	ubiquitin specific peptidase 18	0.014
CASP5	caspase 5, apoptosis-related cysteine peptidase	0.014
FPR2	formyl peptide receptor 2	0.014
PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	0.013
AIM2	absent in melanoma 2	0.013
UBA7	ubiquitin-like modifier activating enzyme 7	0.013
USP4	ubiquitin specific peptidase 4 (proto-oncogene)	0.013
TUBA1A	tubulin, alpha 1a	0.013
IRF5	interferon regulatory factor 5	0.013	Human
SIGLEC10	sialic acid binding Ig-like lectin 10	0.012
MAFB	v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)	0.012
TLR1	toll-like receptor 1	0.012	Human
ISG15	ISG15 ubiquitin-like modifier	0.012
RTP4	receptor (chemosensory) transporter protein 4	0.012
TRADD	TNFRSF1A-associated via death domain	0.012
LILRA3	leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3	0.012	Human
PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator	0.012
TLR7	toll-like receptor 7	0.012
CSK	c-src tyrosine kinase	0.012
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.011	Human
TNF	tumor necrosis factor	0.011
TCL1A	T-cell leukemia/lymphoma 1A	0.011
BIN2	bridging integrator 2	0.011
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.011
CXCL10	chemokine (C-X-C motif) ligand 10	0.011
PLEK	pleckstrin	0.011
CD300A	CD300a molecule	0.011
RASSF4	Ras association (RalGDS/AF-6) domain family member 4	0.011
KIAA1274	KIAA1274	0.011
ROS1	c-ros oncogene 1 , receptor tyrosine kinase	0.011
ETV7	ets variant 7	0.011
SIGLEC5	sialic acid binding Ig-like lectin 5	0.010
BTN3A1	butyrophilin, subfamily 3, member A1	0.010
EMR1	egf-like module containing, mucin-like, hormone receptor-like 1	0.010
ADAP2	ArfGAP with dual PH domains 2	0.010
S100A12	S100 calcium binding protein A12	0.010
CD68	CD68 molecule	0.010
PRDM1	PR domain containing 1, with ZNF domain	0.010
CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	0.010
CD22	CD22 molecule	0.010
C13orf18	chromosome 13 open reading frame 18	0.010