Homo sapiens

0 known processes

TJP1

tight junction protein 1 (zona occludens 1)

(Aliases: ZO-1,MGC133289,DKFZp686M05161)

TJP1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
epithelial cell differentiation GO:0030855 141 0.998
cell junction organization GO:0034330 79 0.997
Fly
cell junction assembly GO:0034329 67 0.992
Fly
regulation of atrial cardiac muscle cell membrane depolarization GO:0060371 6 0.982
cell development GO:0048468 328 0.972
Fly
embryonic skeletal joint development GO:0072498 2 0.971
regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002858 6 0.967
epidermal cell differentiation GO:0009913 45 0.946
cell cell junction organization GO:0045216 69 0.939
Fly
natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002420 6 0.919
regulation of ion transport GO:0043269 189 0.880
epithelial cell development GO:0002064 34 0.878
cellular amino acid metabolic process GO:0006520 116 0.845
biological adhesion GO:0022610 331 0.819
Fly
natural killer cell mediated immune response to tumor cell GO:0002423 6 0.774
cell adhesion GO:0007155 325 0.772
Fly
keratinocyte differentiation GO:0030216 36 0.770
multicellular organismal signaling GO:0035637 34 0.761
actin filament based process GO:0030029 224 0.748
lens development in camera type eye GO:0002088 2 0.738
vasculature development GO:0001944 181 0.720
regulation of ion transmembrane transport GO:0034765 132 0.718
embryonic skeletal joint morphogenesis GO:0060272 2 0.707
anatomical structure formation involved in morphogenesis GO:0048646 284 0.696
Mouse
actin filament organization GO:0007015 128 0.679
actin cytoskeleton organization GO:0030036 207 0.669
cell cell junction assembly GO:0007043 25 0.654
Fly
regulation of anatomical structure morphogenesis GO:0022603 286 0.651
Fly
regulation of membrane repolarization GO:0060306 16 0.641
cellular extravasation GO:0045123 21 0.596
regulation of actin filament polymerization GO:0030833 50 0.592
regulation of membrane potential GO:0042391 95 0.581
regulation of ion homeostasis GO:2000021 73 0.579
epithelium development GO:0060429 227 0.579
Fly
angiogenesis GO:0001525 147 0.569
regulation of cellular component size GO:0032535 82 0.563
system process GO:0003008 349 0.562
Mouse Rat
regulation of bone mineralization GO:0030500 29 0.560
cell communication by electrical coupling GO:0010644 5 0.559
regulation of ventricular cardiac muscle cell membrane repolarization GO:0060307 10 0.559
blood vessel morphogenesis GO:0048514 162 0.555
single organismal cell cell adhesion GO:0016337 148 0.529
Fly
cofactor metabolic process GO:0051186 87 0.493
regulation of potassium ion transmembrane transport GO:1901379 20 0.486
regulation of protein polymerization GO:0032271 63 0.483
biomineral tissue development GO:0031214 39 0.475
cardiac conduction GO:0061337 23 0.467
regulation of cell differentiation GO:0045595 393 0.453
regulation of cellular component biogenesis GO:0044087 281 0.430
regulation of epithelial cell differentiation GO:0030856 24 0.427
embryonic digit morphogenesis GO:0042733 6 0.417
positive regulation of gtpase activity GO:0043547 166 0.413
tight junction assembly GO:0070830 14 0.406
vesicle mediated transport GO:0016192 371 0.404
microtubule cytoskeleton organization GO:0000226 176 0.391
purine ribonucleoside metabolic process GO:0046128 437 0.382
glycosyl compound catabolic process GO:1901658 413 0.376
regulation of heart contraction GO:0008016 50 0.375
membrane organization GO:0061024 292 0.375
circulatory system process GO:0003013 113 0.364
Rat
circulatory system development GO:0072359 262 0.356
heart process GO:0003015 62 0.355
positive regulation of ras gtpase activity GO:0032320 117 0.355
positive regulation of immunoglobulin mediated immune response GO:0002891 4 0.348
regulation of cellular ketone metabolic process GO:0010565 50 0.330
purine nucleoside triphosphate metabolic process GO:0009144 412 0.327
tissue morphogenesis GO:0048729 96 0.300
Fly
membrane repolarization GO:0086009 23 0.296
regulation of actin polymerization or depolymerization GO:0008064 56 0.295
purine ribonucleoside catabolic process GO:0046130 398 0.289
single organism cell adhesion GO:0098602 179 0.288
Fly
adult heart development GO:0007512 6 0.284
hematopoietic or lymphoid organ development GO:0048534 186 0.282
sensory perception GO:0007600 103 0.280
Mouse
heart contraction GO:0060047 62 0.274
cell cell signaling GO:0007267 155 0.271
Fly
regulation of muscle organ development GO:0048634 27 0.266
regulation of transmembrane transport GO:0034762 139 0.265
regulation of angiogenesis GO:0045765 92 0.264
adherens junction organization GO:0034332 36 0.264
Fly
positive regulation of cellular component movement GO:0051272 181 0.260
cardiovascular system development GO:0072358 262 0.258
regulation of actin filament based process GO:0032970 141 0.258
regeneration GO:0031099 4 0.258
regulation of establishment of protein localization GO:0070201 242 0.253
ossification GO:0001503 121 0.250
single organism membrane organization GO:0044802 268 0.250
ion transmembrane transport GO:0034220 338 0.247
bone mineralization GO:0030282 34 0.243
membrane fusion GO:0061025 43 0.242
negative regulation of phosphorus metabolic process GO:0010563 267 0.241
amine metabolic process GO:0009308 44 0.241
cellular amine metabolic process GO:0044106 41 0.240
regulation of ventricular cardiac muscle cell membrane depolarization GO:0060373 4 0.240
cell projection assembly GO:0030031 126 0.238
response to wounding GO:0009611 168 0.238
sensory perception of sound GO:0007605 37 0.236
Mouse
positive regulation of glial cell proliferation GO:0060252 2 0.235
blood vessel development GO:0001568 172 0.235
neuron development GO:0048666 113 0.233
Fly
positive regulation of b cell mediated immunity GO:0002714 4 0.231
positive regulation of ossification GO:0045778 32 0.231
positive regulation of muscle organ development GO:0048636 7 0.230
regulation of muscle tissue development GO:1901861 26 0.227
small gtpase mediated signal transduction GO:0007264 78 0.226
negative regulation of cell motility GO:2000146 104 0.225
cellular modified amino acid metabolic process GO:0006575 64 0.224
transmembrane transport GO:0055085 399 0.224
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.222
regulation of membrane depolarization GO:0003254 19 0.219
positive regulation of cellular component organization GO:0051130 376 0.218
positive regulation of nucleotide metabolic process GO:0045981 230 0.218
purine nucleoside triphosphate catabolic process GO:0009146 392 0.216
generation of neurons GO:0048699 152 0.216
Fly
multi organism membrane organization GO:0044803 12 0.215
chemical homeostasis GO:0048878 306 0.214
Rat
organ morphogenesis GO:0009887 147 0.209
Fly
regulation of protein localization GO:0032880 296 0.204
regulation of rho protein signal transduction GO:0035023 79 0.203
actin filament polymerization GO:0030041 45 0.202
neuron differentiation GO:0030182 138 0.202
Fly
actomyosin structure organization GO:0031032 59 0.201
regulation of actin cytoskeleton organization GO:0032956 116 0.197
cell substrate junction assembly GO:0007044 35 0.193
growth GO:0040007 202 0.190
purine ribonucleotide catabolic process GO:0009154 404 0.190
cytoplasmic transport GO:0016482 379 0.181
regulation of system process GO:0044057 101 0.181
regulation of cellular amine metabolic process GO:0033238 11 0.176
rho protein signal transduction GO:0007266 26 0.175
cell competition in a multicellular organism GO:0035212 1 0.168
regulation of gtp catabolic process GO:0033124 180 0.165
cellular protein complex assembly GO:0043623 188 0.162
positive regulation of cellular catabolic process GO:0031331 284 0.161
positive regulation of mast cell activation GO:0033005 2 0.161
skin development GO:0043588 76 0.160
chemotaxis GO:0006935 157 0.159
intermediate filament based process GO:0045103 17 0.157
regulation of cell migration GO:0030334 289 0.156
peripheral nervous system development GO:0007422 2 0.156
negative regulation of angiogenesis GO:0016525 39 0.156
methylation GO:0032259 106 0.153
establishment of protein localization to membrane GO:0090150 121 0.151
embryonic hemopoiesis GO:0035162 4 0.151
blood circulation GO:0008015 113 0.147
Rat
leukocyte cell cell adhesion GO:0007159 37 0.147
response to lipid GO:0033993 206 0.146
Rat
regulation of potassium ion transmembrane transporter activity GO:1901016 16 0.144
hemopoiesis GO:0030097 180 0.139
mesenchymal cell differentiation GO:0048762 52 0.139
positive regulation of developmental process GO:0051094 314 0.138
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 11 0.138
determination of left right symmetry GO:0007368 11 0.137
muscle structure development GO:0061061 98 0.136
endomembrane system organization GO:0010256 196 0.135
negative regulation of cell migration GO:0030336 102 0.134
gtp catabolic process GO:0006184 237 0.133
regulation of epidermal cell differentiation GO:0045604 15 0.131
kidney development GO:0001822 53 0.130
negative regulation of cellular component movement GO:0051271 106 0.130
regulation of actin filament length GO:0030832 56 0.130
positive regulation of cell differentiation GO:0045597 211 0.128
negative regulation of transport GO:0051051 176 0.127
multi organism membrane fusion GO:0044800 3 0.125
regulation of ras gtpase activity GO:0032318 128 0.124
purine nucleoside catabolic process GO:0006152 398 0.122
positive regulation of endocytosis GO:0045807 42 0.122
tissue regeneration GO:0042246 3 0.120
regulation of defense response GO:0031347 154 0.120
positive regulation of defense response GO:0031349 87 0.119
neurogenesis GO:0022008 169 0.118
Fly
gap junction assembly GO:0016264 2 0.116
renal system development GO:0072001 63 0.116
immune effector process GO:0002252 159 0.114
embryonic morphogenesis GO:0048598 85 0.113
Fly
embryonic appendage morphogenesis GO:0035113 9 0.112
negative regulation of protein metabolic process GO:0051248 391 0.112
embryonic organ development GO:0048568 36 0.111
embryonic organ morphogenesis GO:0048562 24 0.108
determination of bilateral symmetry GO:0009855 15 0.107
gtp metabolic process GO:0046039 239 0.107
cation transmembrane transport GO:0098655 238 0.107
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.106
regulation of purine nucleotide metabolic process GO:1900542 264 0.106
post embryonic development GO:0009791 2 0.105
epithelium migration GO:0090132 119 0.104
urogenital system development GO:0001655 65 0.103
jnk cascade GO:0007254 80 0.102
apical junction assembly GO:0043297 19 0.101
negative regulation of cellular protein metabolic process GO:0032269 353 0.100
tube morphogenesis GO:0035239 95 0.100
Fly
cellular component assembly involved in morphogenesis GO:0010927 73 0.099
neurological system process GO:0050877 163 0.097
Mouse
actin polymerization or depolymerization GO:0008154 56 0.097
cdc42 protein signal transduction GO:0032488 4 0.097
embryonic heart tube morphogenesis GO:0003143 8 0.097
cellular potassium ion transport GO:0071804 60 0.095
adult locomotory behavior GO:0008344 1 0.095
endocrine process GO:0050886 25 0.095
positive regulation of nucleotide catabolic process GO:0030813 185 0.093
plasma membrane organization GO:0007009 115 0.093
nervous system development GO:0007399 293 0.092
Fly
regulation of rho gtpase activity GO:0032319 66 0.092
microtubule based process GO:0007017 210 0.091
endothelium development GO:0003158 33 0.090
guanosine containing compound catabolic process GO:1901069 239 0.089
keratinization GO:0031424 2 0.089
heart looping GO:0001947 7 0.086
regulation of immune response GO:0050776 201 0.086
purine nucleotide catabolic process GO:0006195 405 0.086
entry into host GO:0044409 25 0.086
positive regulation of cellular amine metabolic process GO:0033240 7 0.085
regulation of nucleotide catabolic process GO:0030811 205 0.084
focal adhesion assembly GO:0048041 30 0.083
cell substrate adherens junction assembly GO:0007045 30 0.083
regulation of homeostatic process GO:0032844 121 0.083
coenzyme metabolic process GO:0006732 65 0.082
regulation of transmembrane transporter activity GO:0022898 74 0.082
nucleoside triphosphate metabolic process GO:0009141 422 0.081
regulation of stress activated mapk cascade GO:0032872 84 0.080
entry into cell of other organism involved in symbiotic interaction GO:0051806 25 0.080
regulation of protein kinase activity GO:0045859 289 0.080
potassium ion transport GO:0006813 62 0.080
microtubule organizing center organization GO:0031023 62 0.079
sensory organ development GO:0007423 52 0.079
Fly
action potential GO:0001508 34 0.078
leukocyte mediated immunity GO:0002443 59 0.078
inner ear morphogenesis GO:0042472 4 0.078
protein polymerization GO:0051258 71 0.078
virion attachment to host cell GO:0019062 5 0.077
organelle assembly GO:0070925 176 0.077
purine containing compound catabolic process GO:0072523 411 0.077
secretion GO:0046903 254 0.076
osteoblast differentiation GO:0001649 92 0.076
muscle organ development GO:0007517 56 0.076
actin cytoskeleton reorganization GO:0031532 37 0.076
viral process GO:0016032 146 0.075
cilium organization GO:0044782 68 0.075
negative regulation of wnt signaling pathway GO:0030178 69 0.075
maintenance of cell polarity GO:0030011 2 0.075
muscle system process GO:0003012 81 0.075
positive regulation of locomotion GO:0040017 186 0.073
sulfur compound metabolic process GO:0006790 101 0.073
regulation of gtpase activity GO:0043087 180 0.072
epidermis development GO:0008544 59 0.072
response to abiotic stimulus GO:0009628 336 0.072
Rat
negative regulation of potassium ion transmembrane transport GO:1901380 5 0.072
i kappab kinase nf kappab signaling GO:0007249 166 0.072
positive regulation of pinocytosis GO:0048549 2 0.071
actin filament bundle assembly GO:0051017 54 0.071
regulation of secretion by cell GO:1903530 177 0.071
ribonucleoside catabolic process GO:0042454 406 0.071
intracellular protein transport GO:0006886 270 0.070
multi organism cellular process GO:0044764 156 0.070
positive regulation of nucleoside metabolic process GO:0045979 186 0.069
cell projection organization GO:0030030 252 0.069
Fly
embryonic skeletal system development GO:0048706 13 0.069
negative regulation of developmental process GO:0051093 247 0.069
establishment of endothelial barrier GO:0061028 16 0.069
positive regulation of map kinase activity GO:0043406 80 0.068
cellular component morphogenesis GO:0032989 314 0.068
Fly
guanosine containing compound metabolic process GO:1901068 244 0.068
regulation of protein import into nucleus GO:0042306 78 0.068
cellular ketone metabolic process GO:0042180 80 0.067
positive regulation of cell proliferation GO:0008284 301 0.067
cellular macromolecular complex assembly GO:0034622 324 0.066
protein localization to membrane GO:0072657 160 0.066
positive regulation of hydrolase activity GO:0051345 331 0.065
multicellular organismal aging GO:0010259 3 0.065
regulation of cellular amino acid metabolic process GO:0006521 6 0.065
ion homeostasis GO:0050801 230 0.064
protein localization to plasma membrane GO:0072659 93 0.064
response to tumor cell GO:0002347 10 0.064
alpha amino acid metabolic process GO:1901605 72 0.064
regulation of blood circulation GO:1903522 59 0.063
camera type eye development GO:0043010 25 0.063
regulation of protein transport GO:0051223 213 0.062
canonical wnt signaling pathway GO:0060070 116 0.062
positive regulation of innate immune response GO:0045089 79 0.062
positive regulation of organelle organization GO:0010638 195 0.061
metal ion transport GO:0030001 272 0.061
determination of adult lifespan GO:0008340 2 0.061
cilium morphogenesis GO:0060271 75 0.061
immune response GO:0006955 307 0.060
regulation of protein complex assembly GO:0043254 147 0.060
potassium ion transmembrane transport GO:0071805 60 0.059
negative regulation of protein transport GO:0051224 75 0.059
nuclear transport GO:0051169 179 0.059
cell projection morphogenesis GO:0048858 129 0.059
Fly
protein catabolic process GO:0030163 325 0.059
memory GO:0007613 3 0.059
regulation of glial cell proliferation GO:0060251 4 0.058
regulation of cytoskeleton organization GO:0051493 177 0.058
embryonic limb morphogenesis GO:0030326 9 0.058
mesenchymal cell development GO:0014031 50 0.057
inorganic ion transmembrane transport GO:0098660 231 0.057
mitotic nuclear division GO:0007067 119 0.057
defense response GO:0006952 315 0.057
glial cell migration GO:0008347 4 0.056
regulation of transferase activity GO:0051338 355 0.056
viral life cycle GO:0019058 132 0.056
regulation of neurogenesis GO:0050767 82 0.055
positive regulation of natural killer cell mediated immunity GO:0002717 12 0.055
metanephric tubule development GO:0072170 3 0.055
centrosome organization GO:0051297 58 0.054
membrane depolarization GO:0051899 26 0.054
embryonic heart tube development GO:0035050 9 0.053
regulation of lymphocyte mediated immunity GO:0002706 33 0.053
bone remodeling GO:0046849 11 0.053
regulation of nervous system development GO:0051960 88 0.053
centrosome duplication GO:0051298 28 0.052
cell substrate adhesion GO:0031589 132 0.052
embryo development GO:0009790 123 0.052
Mouse Fly
regulation of epithelial to mesenchymal transition GO:0010717 37 0.051
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.051
positive regulation of cell motility GO:2000147 177 0.051
susceptibility to natural killer cell mediated cytotoxicity GO:0042271 3 0.051
regulation of fat cell differentiation GO:0045598 23 0.050
cellular response to abiotic stimulus GO:0071214 117 0.050
positive regulation of phosphorylation GO:0042327 394 0.050
ribonucleotide catabolic process GO:0009261 405 0.050
anatomical structure homeostasis GO:0060249 100 0.049
regulation of cytoplasmic transport GO:1903649 149 0.049
positive regulation of cell development GO:0010720 92 0.048
regulation of neuron projection development GO:0010975 57 0.048
regulation of ossification GO:0030278 58 0.048
embryo development ending in birth or egg hatching GO:0009792 34 0.048
Mouse Fly
nucleoside catabolic process GO:0009164 408 0.047
muscle tissue development GO:0060537 62 0.047
negative regulation of programmed cell death GO:0043069 321 0.047
endothelial cell differentiation GO:0045446 26 0.046
innate immune response GO:0045087 178 0.046
neuron migration GO:0001764 11 0.046
neural tube formation GO:0001841 3 0.046
modification dependent protein catabolic process GO:0019941 209 0.045
establishment of protein localization to organelle GO:0072594 172 0.045
leukocyte mediated cytotoxicity GO:0001909 27 0.045
adaptive immune response GO:0002250 49 0.045
epithelial tube morphogenesis GO:0060562 38 0.045
Fly
leukocyte activation GO:0045321 164 0.045
appendage development GO:0048736 23 0.044
limb development GO:0060173 23 0.044
wound healing GO:0042060 115 0.044
cation transport GO:0006812 331 0.044
positive regulation of immune system process GO:0002684 283 0.043
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.043
negative regulation of locomotion GO:0040013 118 0.043
regulation of anatomical structure size GO:0090066 101 0.043
eye development GO:0001654 42 0.043
Fly
adherens junction assembly GO:0034333 34 0.043
Fly
regulation of leukocyte mediated immunity GO:0002703 38 0.042
regulation of immune response to tumor cell GO:0002837 8 0.042
regulation of ras protein signal transduction GO:0046578 155 0.042
positive regulation of rho gtpase activity GO:0032321 56 0.042
positive regulation of axon extension GO:0045773 4 0.042
mitotic cell cycle GO:0000278 326 0.041
regulation of vesicle mediated transport GO:0060627 130 0.041
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.041
regulation of cell morphogenesis GO:0022604 153 0.041
Fly
appendage morphogenesis GO:0035107 16 0.041
regulation of cell cell adhesion GO:0022407 57 0.040
actin filament based movement GO:0030048 17 0.040
regulation of catenin import into nucleus GO:0035412 18 0.040
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.040
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.040
protein kinase b signaling GO:0043491 69 0.040
pericardium development GO:0060039 2 0.040
mapk cascade GO:0000165 288 0.040
regulation of osteoblast differentiation GO:0045667 38 0.039
cell matrix adhesion GO:0007160 85 0.039
regulation of cell motility GO:2000145 299 0.039
regulation of cellular component movement GO:0051270 334 0.038
regulation of smad protein import into nucleus GO:0060390 10 0.038
regulation of synaptic plasticity GO:0048167 3 0.038
regulation of vasculature development GO:1901342 97 0.038
regulation of epidermis development GO:0045682 19 0.038
response to external biotic stimulus GO:0043207 261 0.038
Rat
regulation of kinase activity GO:0043549 314 0.038
protein homooligomerization GO:0051260 100 0.038
actin filament bundle organization GO:0061572 54 0.037
positive regulation of potassium ion transmembrane transport GO:1901381 12 0.037
mesenchyme development GO:0060485 59 0.037
response to radiation GO:0009314 151 0.037
positive regulation of gtp catabolic process GO:0033126 166 0.037
interaction with host GO:0051701 42 0.037
stem cell differentiation GO:0048863 93 0.037
nucleoside monophosphate catabolic process GO:0009125 159 0.037
protein oligomerization GO:0051259 173 0.036
endothelial cell development GO:0001885 18 0.036
determination of heart left right asymmetry GO:0061371 8 0.036
positive regulation of striated muscle tissue development GO:0045844 7 0.036
cell killing GO:0001906 34 0.036
cranial nerve development GO:0021545 4 0.035
regulation of proteolysis GO:0030162 293 0.035
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.035
heart morphogenesis GO:0003007 48 0.035
morphogenesis of an epithelium GO:0002009 60 0.035
Fly
regulation of natural killer cell mediated cytotoxicity GO:0042269 16 0.035
cell part morphogenesis GO:0032990 137 0.034
Fly
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.034
primary neural tube formation GO:0014020 3 0.034
limb morphogenesis GO:0035108 16 0.034
regulation of locomotion GO:0040012 329 0.034
neuromuscular junction development GO:0007528 3 0.034
cellular response to ionizing radiation GO:0071479 32 0.034
ncrna metabolic process GO:0034660 108 0.034
positive regulation of gliogenesis GO:0014015 4 0.033
skeletal system development GO:0001501 79 0.033
centrosome cycle GO:0007098 32 0.033
specification of symmetry GO:0009799 16 0.033
negative regulation of protein phosphorylation GO:0001933 140 0.033
positive regulation of ion transmembrane transporter activity GO:0032414 29 0.033
regulation of immune effector process GO:0002697 91 0.033
regulation of protein localization to nucleus GO:1900180 85 0.033
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.033
developmental maturation GO:0021700 28 0.033
proteasomal protein catabolic process GO:0010498 176 0.032
negative regulation of phosphate metabolic process GO:0045936 267 0.032
apoptotic signaling pathway GO:0097190 268 0.032
immune system development GO:0002520 195 0.032
inorganic cation transmembrane transport GO:0098662 194 0.032
cell activation GO:0001775 213 0.032
cell differentiation involved in kidney development GO:0061005 9 0.032
epithelial cell proliferation GO:0050673 128 0.031
movement in host environment GO:0052126 25 0.031
actin mediated cell contraction GO:0070252 12 0.031
protein targeting GO:0006605 187 0.031
regulation of cell cycle GO:0051726 393 0.031
skeletal system morphogenesis GO:0048705 24 0.030
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.030
tissue migration GO:0090130 119 0.030
regulation of ion transmembrane transporter activity GO:0032412 72 0.030
positive regulation of potassium ion transport GO:0043268 15 0.030
regulation of erk1 and erk2 cascade GO:0070372 99 0.030
post embryonic organ development GO:0048569 1 0.030
tube development GO:0035295 125 0.030
Fly
golgi vesicle transport GO:0048193 80 0.030
positive regulation of protein phosphorylation GO:0001934 313 0.030
negative regulation of catalytic activity GO:0043086 335 0.030
protein ubiquitination GO:0016567 314 0.029
compound eye development GO:0048749 1 0.029
Fly
morphogenesis of embryonic epithelium GO:0016331 4 0.029
Fly
intrinsic apoptotic signaling pathway GO:0097193 127 0.029
adhesion of symbiont to host GO:0044406 8 0.029
regulation of nucleotide metabolic process GO:0006140 269 0.029
nucleus localization GO:0051647 1 0.029
nephron tubule epithelial cell differentiation GO:0072160 3 0.029
oocyte differentiation GO:0009994 2 0.029
neural crest cell development GO:0014032 3 0.028
cartilage development GO:0051216 31 0.028
positive regulation of immune response GO:0050778 159 0.028
regulation of secretion GO:0051046 194 0.028
brain development GO:0007420 97 0.028
negative regulation of secretion GO:0051048 58 0.028
negative regulation of protein maturation GO:1903318 142 0.028
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.028
negative regulation of intracellular transport GO:0032387 60 0.028
regulation of nucleocytoplasmic transport GO:0046822 98 0.028
regulation of leukocyte activation GO:0002694 115 0.027
locomotory behavior GO:0007626 1 0.027
chordate embryonic development GO:0043009 34 0.027
Mouse
organophosphate biosynthetic process GO:0090407 163 0.027
central nervous system development GO:0007417 123 0.027
female gamete generation GO:0007292 2 0.027
muscle cell differentiation GO:0042692 63 0.027

TJP1 disease predictions

Disease DO term ID Size Probability Func Analog Org
hepatobiliary disease DOID:3118 7 1.000
Human
gastrointestinal system disease DOID:77 36 1.000
Human
liver disease DOID:409 7 1.000
Human
congenital heart disease DOID:1682 16 0.998
heart septal defect DOID:1681 14 0.998
heart disease DOID:114 68 0.998
cardiovascular system disease DOID:1287 106 0.998
bone development disease DOID:0080006 55 0.966
bone disease DOID:0080001 88 0.966
dysostosis DOID:1934 22 0.966
musculoskeletal system disease DOID:17 223 0.966
connective tissue disease DOID:65 109 0.966
synostosis DOID:11971 10 0.605
kidney disease DOID:557 36 0.435
urinary system disease DOID:18 40 0.435
bone remodeling disease DOID:0080005 26 0.258
craniometaphyseal dysplasia DOID:0080033 5 0.167
osteosclerosis DOID:4254 16 0.167
sensory system disease DOID:0050155 203 0.102
nervous system disease DOID:863 431 0.102
auditory system disease DOID:2742 53 0.039
muscular disease DOID:0080000 114 0.039
central nervous system disease DOID:331 186 0.037
myopathy DOID:423 104 0.033
muscle tissue disease DOID:66 113 0.033
nonsyndromic deafness DOID:0050563 50 0.032
epilepsy syndrome DOID:1826 41 0.028
brain disease DOID:936 73 0.028
electroclinical syndrome DOID:0050701 32 0.028