IMP

Process View

Homo sapiens

2 genes annotated in human

embryonic skeletal joint morphogenesis

The process in which the anatomical structures of skeletal joints are generated and organized during the embryonic phase. A skeletal joint is the connecting structure between the bones of the skeleton.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "embryonic skeletal joint morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "embryonic skeletal joint morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
COL1A1	collagen, type I, alpha 1	1.000	Human
COL3A1	collagen, type III, alpha 1	1.000	Human
SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	0.992
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.985
COL5A2	collagen, type V, alpha 2	0.968	Human
COL4A1	collagen, type IV, alpha 1	0.965
COL5A1	collagen, type V, alpha 1	0.956	Human
COL1A2	collagen, type I, alpha 2	0.846	Human
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.845
LOX	lysyl oxidase	0.717
TJP1	tight junction protein 1 (zona occludens 1)	0.707
DDR2	discoidin domain receptor tyrosine kinase 2	0.567
PXDN	peroxidasin homolog (Drosophila)	0.544
ADAM12	ADAM metallopeptidase domain 12	0.495
COL11A1	collagen, type XI, alpha 1	0.479	Human
MXRA5	matrix-remodelling associated 5	0.403
COL4A2	collagen, type IV, alpha 2	0.402
APC	adenomatous polyposis coli	0.398
NID2	nidogen 2 (osteonidogen)	0.299
GSK3B	glycogen synthase kinase 3 beta	0.266
POSTN	periostin, osteoblast specific factor	0.262
LAMB1	laminin, beta 1	0.224
COL16A1	collagen, type XVI, alpha 1	0.220
ZFYVE9	zinc finger, FYVE domain containing 9	0.214
COL2A1	collagen, type II, alpha 1	0.194
BMP2	bone morphogenetic protein 2	0.189
NOG	noggin	0.177
THY1	Thy-1 cell surface antigen	0.176
FSTL1	follistatin-like 1	0.170
HOXA10	homeobox A10	0.166
BMP7	bone morphogenetic protein 7	0.163	Mouse
TCF4	transcription factor 4	0.142
FBN1	fibrillin 1	0.131
GLIS2	GLIS family zinc finger 2	0.122
FNDC1	fibronectin type III domain containing 1	0.109
LAMC1	laminin, gamma 1 (formerly LAMB2)	0.108
SMAD7	SMAD family member 7	0.089
BTRC	beta-transducin repeat containing	0.083
EMD	emerin	0.076
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.075
CAV1	caveolin 1, caveolae protein, 22kDa	0.069
COL6A1	collagen, type VI, alpha 1	0.068
CRMP1	collapsin response mediator protein 1	0.063
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.058
ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)	0.056
COL10A1	collagen, type X, alpha 1	0.053
CDH5	cadherin 5, type 2 (vascular endothelium)	0.051
CTHRC1	collagen triple helix repeat containing 1	0.047
HOXC6	homeobox C6	0.043
THBS1	thrombospondin 1	0.041
COL12A1	collagen, type XII, alpha 1	0.040
TWIST1	twist homolog 1 (Drosophila)	0.036
BMPR1A	bone morphogenetic protein receptor, type IA	0.036
HOXB5	homeobox B5	0.035
BGN	biglycan	0.034
PDGFA	platelet-derived growth factor alpha polypeptide	0.031
FERMT2	fermitin family member 2	0.030
FKBP10	FK506 binding protein 10, 65 kDa	0.029
CCDC80	coiled-coil domain containing 80	0.028
SOX11	SRY (sex determining region Y)-box 11	0.028
ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2	0.028
HOXC10	homeobox C10	0.027
ANGPTL2	angiopoietin-like 2	0.026
LRRC17	leucine rich repeat containing 17	0.025
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.024
MSX1	msh homeobox 1	0.023
PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha	0.023
PDGFRL	platelet-derived growth factor receptor-like	0.022
WWTR1	WW domain containing transcription regulator 1	0.022
PTK7	PTK7 protein tyrosine kinase 7	0.021
CDC42BPB	CDC42 binding protein kinase beta (DMPK-like)	0.021
OLFML3	olfactomedin-like 3	0.020
UNC5B	unc-5 homolog B (C. elegans)	0.020
PSEN1	presenilin 1	0.020
DACT1	dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)	0.020
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.019
HOXC11	homeobox C11	0.019	Mouse
HOXD10	homeobox D10	0.018
HOXB6	homeobox B6	0.018
HOXD13	homeobox D13	0.018
TGFB1I1	transforming growth factor beta 1 induced transcript 1	0.018
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.018
HOXA13	homeobox A13	0.017
COCH	coagulation factor C homolog, cochlin (Limulus polyphemus)	0.017
SDC2	syndecan 2	0.017
IGFBP3	insulin-like growth factor binding protein 3	0.017
AR	androgen receptor	0.017
GAK	cyclin G associated kinase	0.016
HOXD9	homeobox D9	0.016
C1orf61	chromosome 1 open reading frame 61	0.016
GLT8D2	glycosyltransferase 8 domain containing 2	0.016
HOXA5	homeobox A5	0.015
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.015
ACAN	aggrecan	0.015
BMP1	bone morphogenetic protein 1	0.015
FZD10	frizzled homolog 10 (Drosophila)	0.015
SFRP2	secreted frizzled-related protein 2	0.015
SLC2A10	solute carrier family 2 (facilitated glucose transporter), member 10	0.015
FOXF2	forkhead box F2	0.015
LRP6	low density lipoprotein receptor-related protein 6	0.015
HOXC13	homeobox C13	0.014
WISP1	WNT1 inducible signaling pathway protein 1	0.014
PLXDC1	plexin domain containing 1	0.014
PTHLH	parathyroid hormone-like hormone	0.014
OLFML2B	olfactomedin-like 2B	0.014
HOXC5	homeobox C5	0.014
SFRP4	secreted frizzled-related protein 4	0.013
COL14A1	collagen, type XIV, alpha 1	0.013
GPX8	glutathione peroxidase 8 (putative)	0.013
SOSTDC1	sclerostin domain containing 1	0.013
PLOD2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2	0.013
PMEPA1	prostate transmembrane protein, androgen induced 1	0.013
HOXA7	homeobox A7	0.013
WNT5A	wingless-type MMTV integration site family, member 5A	0.013
BICD1	bicaudal D homolog 1 (Drosophila)	0.013
COL8A2	collagen, type VIII, alpha 2	0.013
HOXD11	homeobox D11	0.012	Mouse
GJD3	gap junction protein, delta 3, 31.9kDa	0.012
MDFI	MyoD family inhibitor	0.012
HOXA11	homeobox A11	0.012	Mouse
ZIC2	Zic family member 2 (odd-paired homolog, Drosophila)	0.012
NID1	nidogen 1	0.012
LRRC15	leucine rich repeat containing 15	0.012
ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)	0.012
PRKCDBP	protein kinase C, delta binding protein	0.012
LTBP1	latent transforming growth factor beta binding protein 1	0.012
NTM	neurotrimin	0.011
PRSS23	protease, serine, 23	0.011
HYAL1	hyaluronoglucosaminidase 1	0.011
MYO1B	myosin IB	0.011
HOXB9	homeobox B9	0.011
COL9A2	collagen, type IX, alpha 2	0.011
NKX3-2	NK3 homeobox 2	0.011
FOXD1	forkhead box D1	0.011
WNT11	wingless-type MMTV integration site family, member 11	0.011
LTBP2	latent transforming growth factor beta binding protein 2	0.011
DVL2	dishevelled, dsh homolog 2 (Drosophila)	0.011
OCLN	occludin	0.011
HOXB7	homeobox B7	0.011
FBN2	fibrillin 2	0.010
FBXW11	F-box and WD repeat domain containing 11	0.010
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.010
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.010
COL9A1	collagen, type IX, alpha 1	0.010
IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1	0.010