Mus musculus

35 known processes

Cxcr2

chemokine (C-X-C motif) receptor 2

(Aliases: Il8rb,Gpcr16,IL8RA,CD128,CDw128,mIL-8RH,IL-8rb,IL-8Rh,Cmkar2)

Cxcr2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of inflammatory response GO:0050727 147 0.912
Mouse
neutrophil chemotaxis GO:0030593 36 0.819
Human Mouse Rat
cell chemotaxis GO:0060326 81 0.758
Human Mouse Rat
inflammatory response GO:0006954 244 0.711
Mouse Rat
leukocyte chemotaxis GO:0030595 69 0.685
Human Mouse Rat
neutrophil migration GO:1990266 37 0.675
Human Mouse Rat
granulocyte migration GO:0097530 43 0.662
Human Mouse Rat
chemotaxis GO:0006935 247 0.609
Human Mouse Rat
cytokine mediated signaling pathway GO:0019221 115 0.607
myeloid leukocyte migration GO:0097529 57 0.570
Human Mouse Rat
regulation of neutrophil migration GO:1902622 14 0.569
Mouse Rat
inflammatory response to antigenic stimulus GO:0002437 30 0.553
Mouse Rat
cellular response to cytokine stimulus GO:0071345 189 0.552
myeloid leukocyte mediated immunity GO:0002444 42 0.525
Mouse
positive regulation of monocyte chemotaxis GO:0090026 2 0.525
Mouse
monocyte extravasation GO:0035696 2 0.519
Mouse
immune effector process GO:0002252 321 0.506
Mouse
leukocyte activation involved in immune response GO:0002366 126 0.496
Mouse
acute inflammatory response GO:0002526 41 0.461
Mouse Rat
cytokine metabolic process GO:0042107 71 0.442
Mouse
positive regulation of defense response GO:0031349 124 0.437
Mouse
eosinophil activation involved in immune response GO:0002278 1 0.418
Mouse
immune response regulating signaling pathway GO:0002764 125 0.414
Mouse
regulation of cell activation GO:0050865 289 0.413
Mouse
regulation of cytokine biosynthetic process GO:0042035 59 0.411
Mouse
regulation of lymphocyte activation GO:0051249 240 0.407
Mouse
regulation of cytokine production GO:0001817 266 0.395
Mouse
t helper 17 cell chemotaxis GO:0035705 1 0.389
Mouse
regulation of monocyte extravasation GO:2000437 2 0.388
Mouse
regulation of immunological synapse formation GO:2000520 2 0.385
Mouse
granulocyte chemotaxis GO:0071621 39 0.383
Human Mouse Rat
regulation of granulocyte chemotaxis GO:0071622 17 0.377
Mouse Rat
regulation of chemokine production GO:0032642 30 0.376
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.376
Mouse
myeloid leukocyte activation GO:0002274 83 0.367
Human Mouse
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.352
regulation of vesicle mediated transport GO:0060627 139 0.351
Mouse
cytokine production GO:0001816 319 0.347
Mouse
negative regulation of adaptive immune response GO:0002820 25 0.346
positive regulation of lymphocyte activation GO:0051251 140 0.331
Mouse
regulation of multi organism process GO:0043900 111 0.326
defense response to other organism GO:0098542 197 0.304
defense response to gram positive bacterium GO:0050830 50 0.303
defense response to bacterium GO:0042742 119 0.300
regulation of neutrophil chemotaxis GO:0090022 14 0.291
Mouse Rat
eosinophil degranulation GO:0043308 1 0.283
Mouse
negative regulation of immune system process GO:0002683 209 0.282
Mouse Rat
positive regulation of neutrophil chemotaxis GO:0090023 12 0.266
Mouse Rat
myeloid leukocyte differentiation GO:0002573 119 0.264
regulation of vascular endothelial growth factor production GO:0010574 13 0.256
Mouse
response to molecule of bacterial origin GO:0002237 143 0.254
Mouse
immune response activating signal transduction GO:0002757 116 0.254
Mouse
regulation of response to wounding GO:1903034 189 0.252
Mouse
negative regulation of leukocyte mediated immunity GO:0002704 29 0.252
Mouse
regulation of adaptive immune response GO:0002819 90 0.252
Mouse
ameboidal type cell migration GO:0001667 128 0.250
Mouse
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.250
Mouse
leukocyte differentiation GO:0002521 342 0.246
Mouse
interaction with symbiont GO:0051702 14 0.244
helper t cell chemotaxis GO:0035704 1 0.243
Mouse
interleukin 12 secretion GO:0072610 3 0.242
Mouse
divalent inorganic cation homeostasis GO:0072507 138 0.241
Mouse Rat
action potential GO:0001508 78 0.237
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.236
Mouse
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.233
Mouse
negative regulation of inflammatory response to antigenic stimulus GO:0002862 10 0.232
positive regulation of t cell costimulation GO:2000525 2 0.229
Mouse
keratinocyte migration GO:0051546 3 0.226
positive regulation of cytokine production GO:0001819 174 0.225
Mouse
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.223
Mouse
myeloid cell activation involved in immune response GO:0002275 34 0.222
Mouse
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.221
Mouse
humoral immune response GO:0006959 57 0.219
Mouse
positive regulation of chemotaxis GO:0050921 38 0.213
Mouse Rat
regulation of defense response GO:0031347 233 0.211
Mouse
negative regulation of secretion GO:0051048 61 0.209
Mouse
interspecies interaction between organisms GO:0044419 83 0.206
natural killer cell activation GO:0030101 44 0.203
innate immune response in mucosa GO:0002227 3 0.203
regulation of myeloid leukocyte mediated immunity GO:0002886 25 0.201
Mouse
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.201
Mouse
negative regulation of secretion by cell GO:1903531 54 0.201
Mouse
response to lipopolysaccharide GO:0032496 128 0.198
Mouse
acute inflammatory response to antigenic stimulus GO:0002438 12 0.197
Mouse Rat
killing of cells in other organism involved in symbiotic interaction GO:0051883 13 0.197
axon ensheathment GO:0008366 76 0.196
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.192
Mouse
regulation of dendritic cell chemotaxis GO:2000508 1 0.192
Mouse
chemokine metabolic process GO:0050755 10 0.191
regulation of leukocyte differentiation GO:1902105 159 0.188
eosinophil activation GO:0043307 1 0.187
Mouse
negative regulation of cell proliferation GO:0008285 296 0.187
eosinophil mediated immunity GO:0002447 1 0.181
Mouse
positive regulation of angiogenesis GO:0045766 46 0.178
Mouse Rat
nitrogen compound transport GO:0071705 271 0.178
protein secretion GO:0009306 111 0.173
Mouse
monocarboxylic acid biosynthetic process GO:0072330 61 0.171
regulation of cell motility GO:2000145 236 0.170
Mouse Rat
macrophage chemotaxis GO:0048246 14 0.170
Mouse
myeloid cell apoptotic process GO:0033028 22 0.169
Mouse Rat
negative regulation of cell activation GO:0050866 111 0.167
Mouse
regulation of hypersensitivity GO:0002883 10 0.167
Mouse
positive regulation of immunological synapse formation GO:2000522 1 0.165
Mouse
killing by host of symbiont cells GO:0051873 11 0.164
regulation of exocytosis GO:0017157 61 0.163
Mouse
gliogenesis GO:0042063 141 0.161
Mouse
negative regulation of chemokine production GO:0032682 4 0.161
adaptive immune response GO:0002250 155 0.159
Mouse
macrophage activation GO:0042116 27 0.159
Mouse
regulation of mast cell activation GO:0033003 21 0.158
positive regulation of monocyte extravasation GO:2000439 1 0.157
Mouse
vascular endothelial growth factor production GO:0010573 13 0.150
Mouse
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.145
Mouse
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 26 0.145
Mouse
cytokine biosynthetic process GO:0042089 68 0.144
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.142
Mouse
exocytosis GO:0006887 121 0.142
Mouse
calcium mediated signaling GO:0019722 46 0.140
positive regulation of hematopoietic stem cell migration GO:2000473 1 0.138
Mouse
activation of immune response GO:0002253 138 0.138
Mouse
positive regulation of chemokine secretion GO:0090197 4 0.138
positive regulation of behavior GO:0048520 40 0.138
Mouse Rat
g protein coupled receptor signaling pathway GO:0007186 243 0.137
lymphocyte mediated immunity GO:0002449 139 0.136
activation of mapk activity involved in innate immune response GO:0035419 2 0.135
cell activation involved in immune response GO:0002263 126 0.131
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.129
production of molecular mediator of immune response GO:0002440 103 0.129
ensheathment of neurons GO:0007272 76 0.127
Mouse
hematopoietic stem cell migration GO:0035701 1 0.126
Mouse
regulation of cell cycle GO:0051726 281 0.125
neutrophil mediated immunity GO:0002446 19 0.124
t cell activation GO:0042110 289 0.123
Mouse
regulation of inflammatory response to antigenic stimulus GO:0002861 21 0.122
Mouse
positive regulation of t cell extravasation GO:2000409 2 0.121
Mouse
chemokine production GO:0032602 34 0.121
negative regulation of immune effector process GO:0002698 55 0.115
Mouse
membrane organization GO:0061024 245 0.112
Mouse
cell killing GO:0001906 67 0.110
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.109
Mouse
regulation of protein localization GO:0032880 231 0.108
Mouse
cation homeostasis GO:0055080 212 0.108
Mouse Rat
immune complex clearance GO:0002434 2 0.107
Mouse
regulation of macrophage activation GO:0043030 17 0.107
stem cell differentiation GO:0048863 268 0.106
positive regulation of granulocyte chemotaxis GO:0071624 12 0.105
Mouse Rat
lymphocyte proliferation GO:0046651 164 0.105
Mouse
leukocyte mediated immunity GO:0002443 174 0.105
Mouse
disruption by host of symbiont cells GO:0051852 11 0.104
lymphocyte differentiation GO:0030098 242 0.103
Mouse
regulation of immunoglobulin mediated immune response GO:0002889 37 0.103
positive regulation of response to wounding GO:1903036 66 0.103
Mouse
regulation of t cell costimulation GO:2000523 2 0.103
Mouse
positive regulation of inflammatory response GO:0050729 47 0.102
Mouse
intracellular protein transport GO:0006886 204 0.102
cell adhesion GO:0007155 329 0.100
positive regulation of chemokine production GO:0032722 22 0.100
blood vessel morphogenesis GO:0048514 285 0.099
Mouse Rat
muscle tissue development GO:0060537 308 0.099
peptidyl amino acid modification GO:0018193 336 0.098
interferon gamma production GO:0032609 67 0.098
Mouse
cytokine secretion GO:0050663 72 0.097
Mouse
innate immune response GO:0045087 157 0.096
Mouse
alpha beta t cell activation GO:0046631 91 0.096
Mouse
positive regulation of interferon gamma production GO:0032729 39 0.095
Mouse
myeloid cell differentiation GO:0030099 233 0.095
Mouse
t cell extravasation GO:0072683 4 0.094
Mouse
antibacterial peptide production GO:0002778 2 0.093
glycoprotein metabolic process GO:0009100 116 0.091
Mouse
positive regulation of neutrophil migration GO:1902624 12 0.091
Mouse Rat
organic acid biosynthetic process GO:0016053 86 0.090
cellular response to lipopolysaccharide GO:0071222 77 0.090
axonogenesis GO:0007409 274 0.088
Mouse
regulation of secretion by cell GO:1903530 249 0.087
Mouse
epithelial tube morphogenesis GO:0060562 303 0.086
Mouse Rat
hypersensitivity GO:0002524 10 0.086
Mouse
positive regulation of immune complex clearance by monocytes and macrophages GO:0090265 2 0.086
Mouse
innate immune response activating signal transduction GO:0002758 50 0.086
positive regulation of cell motility GO:2000147 116 0.086
Mouse Rat
leukocyte migration GO:0050900 124 0.086
Human Mouse Rat
positive regulation of nervous system development GO:0051962 221 0.085
Mouse
regulation of cell migration GO:0030334 219 0.085
Mouse Rat
positive regulation of tumor necrosis factor biosynthetic process GO:0042535 8 0.084
Mouse
cellular amide metabolic process GO:0043603 58 0.084
negative regulation of multi organism process GO:0043901 68 0.083
negative regulation of phagocytosis GO:0050765 4 0.083
cellular extravasation GO:0045123 17 0.083
Mouse
negative regulation of t cell mediated immunity GO:0002710 9 0.082
negative regulation of macrophage apoptotic process GO:2000110 3 0.081
Mouse
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 23 0.081
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.081
Mouse
positive regulation of acute inflammatory response GO:0002675 16 0.081
Mouse
dendritic cell chemotaxis GO:0002407 7 0.081
Mouse
regulation of interleukin 2 production GO:0032663 28 0.080
Mouse
negative regulation of exocytosis GO:0045920 12 0.080
Mouse
modification of morphology or physiology of other organism GO:0035821 18 0.080
angiogenesis GO:0001525 201 0.080
Mouse Rat
digestive tract morphogenesis GO:0048546 147 0.079
interleukin 18 mediated signaling pathway GO:0035655 2 0.079
regulation of chemokine secretion GO:0090196 4 0.079
wound healing GO:0042060 157 0.079
regulation of tumor necrosis factor biosynthetic process GO:0042534 10 0.079
Mouse
t cell receptor signaling pathway GO:0050852 46 0.079
Mouse
leukocyte proliferation GO:0070661 172 0.078
Mouse
regulation of tumor necrosis factor production GO:0032680 49 0.077
Mouse
chemokine secretion GO:0090195 5 0.077
regulation of hormone levels GO:0010817 211 0.077
positive regulation of mapk cascade GO:0043410 170 0.077
negative regulation of defense response GO:0031348 77 0.076
Mouse
regulation of t helper 1 type immune response GO:0002825 17 0.076
Mouse
regulation of b cell mediated immunity GO:0002712 37 0.075
maintenance of location GO:0051235 89 0.075
Mouse
regulation of t cell differentiation GO:0045580 83 0.075
cytosolic calcium ion transport GO:0060401 48 0.073
Mouse
small molecule biosynthetic process GO:0044283 132 0.073
microglial cell activation GO:0001774 3 0.073
Mouse
positive regulation vascular endothelial growth factor production GO:0010575 10 0.072
positive regulation of inflammatory response to antigenic stimulus GO:0002863 11 0.071
Mouse
regulation of mapk cascade GO:0043408 248 0.071
positive regulation of leukocyte differentiation GO:1902107 86 0.071
positive regulation of protein modification process GO:0031401 299 0.071
immunoglobulin production GO:0002377 73 0.071
neutrophil mediated killing of gram positive bacterium GO:0070946 2 0.071
neuronal action potential GO:0019228 54 0.070
organonitrogen compound biosynthetic process GO:1901566 192 0.069
regulation of brown fat cell proliferation GO:0070347 1 0.069
negative regulation of response to wounding GO:1903035 77 0.068
interleukin 6 production GO:0032635 58 0.068
phagocytosis GO:0006909 66 0.068
b cell differentiation GO:0030183 78 0.068
gland development GO:0048732 330 0.068
regulation of cellular ketone metabolic process GO:0010565 66 0.067
lysosome localization GO:0032418 20 0.067
negative regulation of eosinophil degranulation GO:0043310 1 0.067
Mouse
regulation of monocyte chemotaxis GO:0090025 3 0.067
Mouse
defense response to virus GO:0051607 68 0.067
regulation of innate immune response GO:0045088 91 0.066
Mouse
response to oxidative stress GO:0006979 123 0.066
myelination GO:0042552 74 0.066
Mouse
negative regulation of molecular function GO:0044092 258 0.066
striated muscle tissue development GO:0014706 293 0.066
regulation of establishment of protein localization GO:0070201 181 0.066
Mouse
regulation of regulated secretory pathway GO:1903305 20 0.065
Mouse
negative regulation of chemokine biosynthetic process GO:0045079 2 0.065
regulation of toll like receptor signaling pathway GO:0034121 20 0.064
regulation of humoral immune response GO:0002920 22 0.063
Mouse
cytoplasmic transport GO:0016482 234 0.063
Mouse
positive regulation of acute inflammatory response to antigenic stimulus GO:0002866 7 0.063
Mouse
interleukin 11 mediated signaling pathway GO:0038154 2 0.062
neural precursor cell proliferation GO:0061351 121 0.062
Mouse
negative regulation of cellular component organization GO:0051129 194 0.061
regulation of hematopoietic stem cell migration GO:2000471 1 0.061
Mouse
regulation of inositol trisphosphate biosynthetic process GO:0032960 3 0.060
positive regulation of phagocytosis GO:0050766 26 0.060
regulation of epithelial cell proliferation GO:0050678 141 0.060
Mouse
positive regulation of glial cell differentiation GO:0045687 21 0.060
Mouse
regulation of type 2 immune response GO:0002828 18 0.059
Mouse
mature dendritic cell differentiation GO:0097029 3 0.059
Mouse
immune complex clearance by monocytes and macrophages GO:0002436 2 0.059
Mouse
cytosolic calcium ion homeostasis GO:0051480 70 0.058
Mouse Rat
response to peptide GO:1901652 136 0.058
regulated secretory pathway GO:0045055 32 0.058
Mouse
regulation of secretion GO:0051046 274 0.058
Mouse
mucosal immune response GO:0002385 13 0.058
cation transport GO:0006812 399 0.058
Mouse
dendritic cell migration GO:0036336 12 0.057
Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.057
negative regulation of signal transduction in absence of ligand GO:1901099 16 0.057
Mouse
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.057
Mouse
regulation of acute inflammatory response GO:0002673 27 0.057
Mouse
b cell activation GO:0042113 161 0.057
ossification GO:0001503 216 0.057
regulation of b cell activation GO:0050864 81 0.057
viral process GO:0016032 41 0.056
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.055
Mouse
regulation of angiogenesis GO:0045765 81 0.055
Mouse Rat
activation of mapk activity GO:0000187 59 0.054
protein targeting GO:0006605 143 0.054
positive regulation of cell activation GO:0050867 158 0.054
Mouse
positive regulation of alpha beta t cell proliferation GO:0046641 12 0.053
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.053
response to acid chemical GO:0001101 111 0.052
negative regulation of interleukin 5 production GO:0032714 4 0.052
second messenger mediated signaling GO:0019932 73 0.052
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.051
chemokine mediated signaling pathway GO:0070098 17 0.051
positive regulation of cellular amine metabolic process GO:0033240 5 0.051
cellular response to hormone stimulus GO:0032870 150 0.051
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.050
Mouse
neuron projection guidance GO:0097485 141 0.050
Mouse
detection of fungus GO:0016046 2 0.050
fatty acid derivative biosynthetic process GO:1901570 15 0.050
negative regulation of regulated secretory pathway GO:1903306 7 0.049
Mouse
regulation of eosinophil degranulation GO:0043309 1 0.049
Mouse
interleukin 33 mediated signaling pathway GO:0038172 1 0.049
cell surface pattern recognition receptor signaling pathway GO:0002752 2 0.049
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.049
negative regulation of inflammatory response GO:0050728 61 0.048
lymphocyte activation involved in immune response GO:0002285 93 0.048
regulation of t cell extravasation GO:2000407 3 0.048
Mouse
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.048
osteoclast differentiation GO:0030316 62 0.048
regulation of cellular amino acid metabolic process GO:0006521 5 0.047
reactive oxygen species metabolic process GO:0072593 84 0.047
chromatin modification GO:0016568 187 0.047
cellular response to dna damage stimulus GO:0006974 207 0.047
regulation of leukocyte proliferation GO:0070663 121 0.047
Mouse
regulation of apoptotic signaling pathway GO:2001233 197 0.047
Mouse
regulation of protein transport GO:0051223 163 0.047
Mouse
cellular lipid metabolic process GO:0044255 323 0.047
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.046
Mouse
positive regulation of inositol phosphate biosynthetic process GO:0060732 2 0.046
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.046
negative regulation of protein secretion GO:0050709 20 0.045
nuclear import GO:0051170 95 0.045
positive regulation of chemokine biosynthetic process GO:0045080 6 0.045
peptide metabolic process GO:0006518 46 0.045
regulation of homeostatic process GO:0032844 182 0.044
Mouse Rat
positive regulation of myeloid cell differentiation GO:0045639 43 0.044
glycoprotein biosynthetic process GO:0009101 89 0.044
Mouse
negative regulation of leukocyte degranulation GO:0043301 7 0.044
Mouse
regulation of chemokine biosynthetic process GO:0045073 8 0.044
positive regulation of granulocyte macrophage colony stimulating factor biosynthetic process GO:0045425 2 0.044
cellular response to peptide hormone stimulus GO:0071375 92 0.044
regulation of lymphocyte differentiation GO:0045619 107 0.044
antigen processing and presentation GO:0019882 47 0.043
Mouse
regulation of interleukin 6 production GO:0032675 55 0.043
regulation of leukocyte mediated immunity GO:0002703 104 0.043
Mouse
negative regulation of cytokine production GO:0001818 84 0.043
positive regulation of cytokine biosynthetic process GO:0042108 40 0.043
Mouse
positive regulation of lymphocyte proliferation GO:0050671 70 0.043
Mouse
regulation of alpha beta t cell activation GO:0046634 53 0.043
Mouse
protein localization to organelle GO:0033365 185 0.043
regulation of intracellular transport GO:0032386 159 0.042
negative regulation of myeloid leukocyte mediated immunity GO:0002887 7 0.042
Mouse
stem cell proliferation GO:0072089 117 0.042
negative regulation of cellular protein metabolic process GO:0032269 247 0.042
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.041
negative regulation of hypersensitivity GO:0002884 3 0.041
oxidation reduction process GO:0055114 342 0.041
mrna transcription GO:0009299 4 0.041
interleukin 12 production GO:0032615 32 0.041
Mouse
transmission of nerve impulse GO:0019226 76 0.041
signal transduction in absence of ligand GO:0038034 55 0.040
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.040
b cell mediated immunity GO:0019724 71 0.040
brown fat cell proliferation GO:0070342 1 0.040
antimicrobial peptide biosynthetic process GO:0002777 2 0.039
positive regulation of epithelial cell proliferation GO:0050679 68 0.039
Mouse
neutrophil differentiation GO:0030223 3 0.039
fc epsilon receptor signaling pathway GO:0038095 3 0.039
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.039
regulation of lymphocyte proliferation GO:0050670 117 0.038
Mouse
leukocyte degranulation GO:0043299 27 0.038
Mouse
interleukin 27 mediated signaling pathway GO:0070106 1 0.038
positive regulation of camp mediated signaling GO:0043950 3 0.038
regulation of mast cell degranulation GO:0043304 16 0.038
regulation of gliogenesis GO:0014013 50 0.038
Mouse
response to radiation GO:0009314 165 0.038
positive regulation of t cell activation GO:0050870 101 0.038
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.038
modification by host of symbiont morphology or physiology GO:0051851 12 0.037
blood coagulation GO:0007596 76 0.037
regulation of membrane potential GO:0042391 192 0.037
positive regulation of calcium mediated signaling GO:0050850 15 0.037
regulation of myeloid leukocyte differentiation GO:0002761 58 0.037
disruption of cells of other organism involved in symbiotic interaction GO:0051818 13 0.036
tumor necrosis factor production GO:0032640 50 0.036
Mouse
mast cell activation involved in immune response GO:0002279 20 0.036
regulation of map kinase activity GO:0043405 120 0.036
negative regulation of lipopolysaccharide mediated signaling pathway GO:0031665 3 0.036
positive regulation of oligodendrocyte differentiation GO:0048714 9 0.036
Mouse
mrna transcription from rna polymerase ii promoter GO:0042789 4 0.036
positive regulation of transferase activity GO:0051347 167 0.036
positive regulation of immune effector process GO:0002699 107 0.035
Mouse
germ cell development GO:0007281 185 0.035
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.035
Mouse
reactive nitrogen species metabolic process GO:2001057 0 0.035
single organism cell adhesion GO:0098602 156 0.035
mapk cascade GO:0000165 281 0.035
nuclear transport GO:0051169 139 0.035
phospholipid metabolic process GO:0006644 87 0.035
apoptotic signaling pathway GO:0097190 306 0.035
Mouse
cellular response to peptide GO:1901653 92 0.035
carboxylic acid biosynthetic process GO:0046394 86 0.035
regulation of myeloid cell differentiation GO:0045637 96 0.035
regulation of osteoclast differentiation GO:0045670 36 0.035
compound eye development GO:0048749 1 0.035
organ or tissue specific immune response GO:0002251 13 0.035
jnk cascade GO:0007254 72 0.035
regulation of cellular response to stress GO:0080135 159 0.034
divalent inorganic cation transport GO:0072511 178 0.034
Mouse
metanephros development GO:0001656 79 0.034
Rat
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.034
cell recognition GO:0008037 83 0.034
Mouse
negative regulation of apoptotic signaling pathway GO:2001234 104 0.034
Mouse
regulation of transferase activity GO:0051338 263 0.034
mast cell mediated immunity GO:0002448 20 0.033
sequestering of metal ion GO:0051238 19 0.033
Mouse
antibacterial peptide biosynthetic process GO:0002780 2 0.033
killing of cells of other organism GO:0031640 13 0.032
cellular calcium ion homeostasis GO:0006874 119 0.032
Mouse Rat
neutrophil mediated killing of symbiont cell GO:0070943 8 0.032
regulation of kinase activity GO:0043549 249 0.032
methylation GO:0032259 134 0.032
regulation of toll like receptor 2 signaling pathway GO:0034135 3 0.032
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.032
Human
antibacterial peptide secretion GO:0002779 1 0.032
branching morphogenesis of an epithelial tube GO:0048754 159 0.032
Mouse
interleukin 8 production GO:0032637 4 0.032
antimicrobial peptide production GO:0002775 2 0.032
cellular ion homeostasis GO:0006873 165 0.032
Mouse Rat
positive regulation of protein kinase activity GO:0045860 144 0.032
positive regulation of macrophage activation GO:0043032 10 0.031
granzyme mediated apoptotic signaling pathway GO:0008626 1 0.031
t helper 1 type immune response GO:0042088 25 0.031
Mouse
protein import into nucleus GO:0006606 95 0.031
amide transport GO:0042886 138 0.030
amine metabolic process GO:0009308 45 0.030
regulation of interferon gamma production GO:0032649 57 0.030
Mouse
regulation of leukocyte degranulation GO:0043300 20 0.030
Mouse
mast cell activation GO:0045576 27 0.030
stimulatory c type lectin receptor signaling pathway GO:0002223 2 0.030
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.030
posttranscriptional regulation of gene expression GO:0010608 155 0.030
cerebral cortex cell migration GO:0021795 44 0.030
Mouse
regulation of chromosome organization GO:0033044 83 0.030
lipid biosynthetic process GO:0008610 179 0.030
regulation of acute inflammatory response to antigenic stimulus GO:0002864 10 0.030
Mouse
regulation of phagocytosis GO:0050764 33 0.030
negative regulation of t cell cytokine production GO:0002725 1 0.030
stem cell development GO:0048864 219 0.030
cell growth GO:0016049 130 0.029
positive regulation of coagulation GO:0050820 13 0.029
positive regulation of protein phosphorylation GO:0001934 242 0.029
neutrophil mediated cytotoxicity GO:0070942 8 0.029
positive regulation of intracellular transport GO:0032388 70 0.029
motor neuron axon guidance GO:0008045 26 0.029
Mouse
negative regulation of bone trabecula formation GO:1900155 1 0.029
regulation of g protein coupled receptor protein signaling pathway GO:0008277 37 0.029
activation of innate immune response GO:0002218 56 0.029
mucopolysaccharide metabolic process GO:1903510 25 0.029
interleukin 2 production GO:0032623 33 0.029
Mouse
regulation of interleukin 12 production GO:0032655 30 0.029
Mouse
immunoglobulin mediated immune response GO:0016064 69 0.028
lymphocyte migration GO:0072676 26 0.028
Mouse
eosinophil migration GO:0072677 3 0.028
t cell costimulation GO:0031295 14 0.028
Mouse
negative regulation of vasculature development GO:1901343 26 0.028
Mouse
interleukin 18 production GO:0032621 4 0.028
regulation of stress activated mapk cascade GO:0032872 69 0.028
regulation of tissue remodeling GO:0034103 38 0.028
regulation of protein secretion GO:0050708 82 0.028
Mouse
positive regulation of innate immune response GO:0045089 80 0.028
microglial cell activation involved in immune response GO:0002282 1 0.028
Mouse
regulation of granulocyte macrophage colony stimulating factor biosynthetic process GO:0045423 2 0.028
macrophage differentiation GO:0030225 20 0.028
single organism nuclear import GO:1902593 95 0.027
forebrain development GO:0030900 302 0.027
Mouse
protein import GO:0017038 101 0.027
positive regulation of exocytosis GO:0045921 20 0.027
embryonic placenta development GO:0001892 98 0.027
antibacterial humoral response GO:0019731 8 0.027
cellular response to follicle stimulating hormone stimulus GO:0071372 1 0.026
skeletal muscle organ development GO:0060538 163 0.026
ribonucleotide metabolic process GO:0009259 291 0.026
positive regulation of map kinase activity GO:0043406 84 0.026
regulation of vasculature development GO:1901342 88 0.026
Mouse Rat
positive regulation of gliogenesis GO:0014015 27 0.026
Mouse
t cell differentiation in thymus GO:0033077 77 0.026
Mouse
sequestering of calcium ion GO:0051208 18 0.026
Mouse
response to hyperoxia GO:0055093 2 0.025
negative regulation of lymphocyte proliferation GO:0050672 45 0.025
cellular response to gonadotropin stimulus GO:0071371 4 0.025
negative regulation of interferon gamma production GO:0032689 18 0.025
positive regulation of hypersensitivity GO:0002885 7 0.025
Mouse
negative regulation of neuron apoptotic process GO:0043524 92 0.025
regulation of histone modification GO:0031056 56 0.025
protein kinase b signaling GO:0043491 74 0.025
glial cell differentiation GO:0010001 131 0.025
Mouse
response to peptide hormone GO:0043434 127 0.025
kidney development GO:0001822 213 0.025
Rat
cellular defense response GO:0006968 6 0.025
Human Mouse
multicellular organismal homeostasis GO:0048871 164 0.024
cd4 positive alpha beta t cell activation GO:0035710 45 0.024
positive regulation of humoral immune response GO:0002922 11 0.024
Mouse
cellular response to insulin stimulus GO:0032869 78 0.024
negative regulation of lymphocyte activation GO:0051250 91 0.024
cellular response to molecule of bacterial origin GO:0071219 83 0.024

Cxcr2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.269
disease of anatomical entity DOID:7 0 0.269
disease of metabolism DOID:0014667 0 0.138
cancer DOID:162 0 0.102
disease of cellular proliferation DOID:14566 0 0.102
organ system cancer DOID:0050686 0 0.102
blood coagulation disease DOID:1247 0 0.061
hematopoietic system disease DOID:74 0 0.061
inherited blood coagulation disease DOID:2214 0 0.043
hemorrhagic disease DOID:2213 0 0.036