IMP

Process View

Mus musculus

11 genes annotated in mouse

disruption by host of symbiont cells

Any process in which an organism has a negative effect on the functioning of the symbiont's cells. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "disruption by host of symbiont cells"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "disruption by host of symbiont cells" (in gray)

Name	Description	Probability	Func Analog Organism
Ctsg	cathepsin G	0.933
S100a9	S100 calcium binding protein A9 (calgranulin B)	0.858
Ngp	neutrophilic granule protein	0.764	Mouse
S100a8	S100 calcium binding protein A8 (calgranulin A)	0.708
Mmp8	matrix metallopeptidase 8	0.663
Mpo	myeloperoxidase	0.601
Cxcl2	chemokine (C-X-C motif) ligand 2	0.557	Mouse
Ccl4	chemokine (C-C motif) ligand 4	0.557
Il1rn	interleukin 1 receptor antagonist	0.532
Saa3	serum amyloid A 3	0.400
Cma1	chymase 1, mast cell	0.390	Mouse
Gzmb	granzyme B	0.379	Mouse
Elane	elastase, neutrophil expressed	0.347
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.341
Irg1	immunoresponsive gene 1	0.319
Clec4d	C-type lectin domain family 4, member d	0.302
Slfn4	schlafen 4	0.291
Il18rap	interleukin 18 receptor accessory protein	0.279
Camp	cathelicidin antimicrobial peptide	0.278
Mcpt4	mast cell protease 4	0.265	Mouse
Il1r2	interleukin 1 receptor, type II	0.222
Ccl7	chemokine (C-C motif) ligand 7	0.220
Cpa3	carboxypeptidase A3, mast cell	0.209
Gzmc	granzyme C	0.205	Mouse
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.202
C5ar1	complement component 5a receptor 1	0.191
Clec4e	C-type lectin domain family 4, member e	0.160
Fasl	Fas ligand (TNF superfamily, member 6)	0.159
Il1b	interleukin 1 beta	0.156
Ccl8	chemokine (C-C motif) ligand 8	0.144
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.143
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.142
Batf	basic leucine zipper transcription factor, ATF-like	0.138
Prg2	proteoglycan 2, bone marrow	0.136
Ccl3	chemokine (C-C motif) ligand 3	0.126
Fpr1	formyl peptide receptor 1	0.119
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.111
Gbp1	guanylate binding protein 1	0.108
Ccl12	chemokine (C-C motif) ligand 12	0.105
Cxcr2	chemokine (C-X-C motif) receptor 2	0.104
Mcpt2	mast cell protease 2	0.103	Mouse
Chi3l3	chitinase 3-like 3	0.102
Ltc4s	leukotriene C4 synthase	0.101
Il1rl1	interleukin 1 receptor-like 1	0.101
Xcl1	chemokine (C motif) ligand 1	0.096
Fcgr1	Fc receptor, IgG, high affinity I	0.096
Ifitm6	interferon induced transmembrane protein 6	0.094
Ccl22	chemokine (C-C motif) ligand 22	0.091
Fpr2	formyl peptide receptor 2	0.088
Il2rb	interleukin 2 receptor, beta chain	0.087
Gzmf	granzyme F	0.086	Mouse
Niacr1	niacin receptor 1	0.083
Gfi1b	growth factor independent 1B	0.080
Ltf	lactotransferrin	0.075
Cma2	chymase 2, mast cell	0.073
Fcer1a	Fc receptor, IgE, high affinity I, alpha polypeptide	0.067
Mmp10	matrix metallopeptidase 10	0.067
Slpi	secretory leukocyte peptidase inhibitor	0.062
Mmp13	matrix metallopeptidase 13	0.060
Rsad2	radical S-adenosyl methionine domain containing 2	0.058
Ccl11	chemokine (C-C motif) ligand 11	0.057
Klra2	killer cell lectin-like receptor, subfamily A, member 2	0.057
Aoah	acyloxyacyl hydrolase	0.056
Ubd	ubiquitin D	0.055
Tg	thyroglobulin	0.054
Serpina3g	serine (or cysteine) peptidase inhibitor, clade A, member 3G	0.053
Mcpt8	mast cell protease 8	0.053	Mouse
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.053
Folr2	folate receptor 2 (fetal)	0.052
Prtn3	proteinase 3	0.051	Mouse
Areg	amphiregulin	0.051
1100001G20Rik	RIKEN cDNA 1100001G20 gene	0.050
Hp	haptoglobin	0.049
Cst7	cystatin F (leukocystatin)	0.049
LOC100504404	h-2 class II histocompatibility antigen, E-K alpha chain-like	0.049
Pgk2	phosphoglycerate kinase 2	0.048
Fosl1	fos-like antigen 1	0.047
Plaur	plasminogen activator, urokinase receptor	0.047
Gdf15	growth differentiation factor 15	0.047
Maff	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)	0.044
Rhag	Rhesus blood group-associated A glycoprotein	0.044
Gp1ba	glycoprotein 1b, alpha polypeptide	0.043
C2	complement component 2 (within H-2S)	0.042
Il1a	interleukin 1 alpha	0.042
Fcna	ficolin A	0.042
Prl2b1	prolactin family 2, subfamily b, member 1	0.040
H2-M9	histocompatibility 2, M region locus 9	0.039
Ccl5	chemokine (C-C motif) ligand 5	0.036
Klrc1	killer cell lectin-like receptor subfamily C, member 1	0.036
Cidec	cell death-inducing DFFA-like effector c	0.035
Tnfaip2	tumor necrosis factor, alpha-induced protein 2	0.035
Cd300lf	CD300 antigen like family member F	0.034
Adipoq	adiponectin, C1Q and collagen domain containing	0.033
Ms4a3	membrane-spanning 4-domains, subfamily A, member 3	0.033
Cxcl1	chemokine (C-X-C motif) ligand 1	0.033
Trim10	tripartite motif-containing 10	0.032
Prol1	proline rich, lacrimal 1	0.032
Il6	interleukin 6	0.031
Ctsw	cathepsin W	0.031
Sh2d2a	SH2 domain protein 2A	0.031
Ly6i	lymphocyte antigen 6 complex, locus I	0.031
Stfa3	stefin A3	0.031
Msr1	macrophage scavenger receptor 1	0.030
Ccl2	chemokine (C-C motif) ligand 2	0.030
Ccr1	chemokine (C-C motif) receptor 1	0.030
Oasl1	2'-5' oligoadenylate synthetase-like 1	0.030
Sva	seminal vesicle antigen	0.030
Nlrp3	NLR family, pyrin domain containing 3	0.029
Nfe2	nuclear factor, erythroid derived 2	0.029
Slfn1	schlafen 1	0.029
Mmp12	matrix metallopeptidase 12	0.028
Gpr97	G protein-coupled receptor 97	0.028
Prx	periaxin	0.028
Rhd	Rh blood group, D antigen	0.028
Gzmd	granzyme D	0.028	Mouse
Tnfsf9	tumor necrosis factor (ligand) superfamily, member 9	0.027
Mx2	myxovirus (influenza virus) resistance 2	0.027
Cd80	CD80 antigen	0.026
Itgb3	integrin beta 3	0.026
Mst1r	macrophage stimulating 1 receptor (c-met-related tyrosine kinase)	0.026
Atf3	activating transcription factor 3	0.026
Ccrl2	chemokine (C-C motif) receptor-like 2	0.026
Alox15	arachidonate 15-lipoxygenase	0.025
Klra9	killer cell lectin-like receptor subfamily A, member 9	0.025
Soat2	sterol O-acyltransferase 2	0.025
Batf2	basic leucine zipper transcription factor, ATF-like 2	0.025
Selp	selectin, platelet	0.025
Ifng	interferon gamma	0.024
Adam8	a disintegrin and metallopeptidase domain 8	0.024
Hemgn	hemogen	0.024
F10	coagulation factor X	0.024
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2	0.023
Ahsp	alpha hemoglobin stabilizing protein	0.023
Cd3e	CD3 antigen, epsilon polypeptide	0.023
Iigp1	interferon inducible GTPase 1	0.023
H2-Q8	histocompatibility 2, Q region locus 8	0.023
Pla2g2a	phospholipase A2, group IIA (platelets, synovial fluid)	0.023
Gzme	granzyme E	0.023	Mouse
Chi3l1	chitinase 3-like 1	0.022
Myf6	myogenic factor 6	0.022
Cldn13	claudin 13	0.022
Marco	macrophage receptor with collagenous structure	0.022
Nkg7	natural killer cell group 7 sequence	0.022
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.021
Clec5a	C-type lectin domain family 5, member a	0.021
Gpr35	G protein-coupled receptor 35	0.021
Ear11	eosinophil-associated, ribonuclease A family, member 11	0.021
Apoh	apolipoprotein H	0.021
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.021
Mfap5	microfibrillar associated protein 5	0.021
Ctse	cathepsin E	0.020
Chi3l4	chitinase 3-like 4	0.020
Cxcl10	chemokine (C-X-C motif) ligand 10	0.020	Mouse
Trem3	triggering receptor expressed on myeloid cells 3	0.020
Dpt	dermatopontin	0.020
Ccl17	chemokine (C-C motif) ligand 17	0.020
Ccl1	chemokine (C-C motif) ligand 1	0.020
Ager	advanced glycosylation end product-specific receptor	0.020
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.020
Nnmt	nicotinamide N-methyltransferase	0.019
Ppbp	pro-platelet basic protein	0.019
Ear2	eosinophil-associated, ribonuclease A family, member 2	0.019
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.019
Lag3	lymphocyte-activation gene 3	0.019
F13a1	coagulation factor XIII, A1 subunit	0.019
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.019
Omt2b	oocyte maturation, beta	0.019
Scgb1a1	secretoglobin, family 1A, member 1 (uteroglobin)	0.019
Guca1a	guanylate cyclase activator 1a (retina)	0.018
Cnn1	calponin 1	0.018
Gpr133	G protein-coupled receptor 133	0.018
Prl7d1	prolactin family 7, subfamily d, member 1	0.018
Prl3d1	prolactin family 3, subfamily d, member 1	0.018
Gypa	glycophorin A	0.018
Cd244	CD244 natural killer cell receptor 2B4	0.017
Gpr84	G protein-coupled receptor 84	0.017
Saa4	serum amyloid A 4	0.017
Ceacam11	carcinoembryonic antigen-related cell adhesion molecule 11	0.017
Isg15	ISG15 ubiquitin-like modifier	0.017
Plunc	palate, lung, and nasal epithelium associated	0.017
Car1	carbonic anhydrase 1	0.016
Fabp4	fatty acid binding protein 4, adipocyte	0.016
Arid5a	AT rich interactive domain 5A (MRF1-like)	0.016
C1qb	complement component 1, q subcomponent, beta polypeptide	0.016
Akap4	A kinase (PRKA) anchor protein 4	0.016
Ccl24	chemokine (C-C motif) ligand 24	0.016
Hist1h3i	histone cluster 1, H3i	0.016
Ltb4r1	leukotriene B4 receptor 1	0.016
Retn	resistin	0.016
Prl7a1	prolactin family 7, subfamily a, member 1	0.016
Sftpd	surfactant associated protein D	0.016	Mouse
Hdc	histidine decarboxylase	0.016
Serpina12	serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12	0.016
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.015
Mgmt	O-6-methylguanine-DNA methyltransferase	0.015
Tnni2	troponin I, skeletal, fast 2	0.015
Itgal	integrin alpha L	0.015
Spic	Spi-C transcription factor (Spi-1/PU.1 related)	0.015
Il3ra	interleukin 3 receptor, alpha chain	0.015
Fcgr4	Fc receptor, IgG, low affinity IV	0.015
Apon	apolipoprotein N	0.015
Lilrb4	leukocyte immunoglobulin-like receptor, subfamily B, member 4	0.015
Svs6	seminal vesicle secretory protein 6	0.015
Tnfrsf23	tumor necrosis factor receptor superfamily, member 23	0.015
Cd96	CD96 antigen	0.015
Sftpa1	surfactant associated protein A1	0.015	Mouse
Prss2	protease, serine, 2	0.014
Myh4	myosin, heavy polypeptide 4, skeletal muscle	0.014
Ch25h	cholesterol 25-hydroxylase	0.014
Ms4a7	membrane-spanning 4-domains, subfamily A, member 7	0.014
Pf4	platelet factor 4	0.014	Mouse
Ang2	angiogenin, ribonuclease A family, member 2	0.014
Il2ra	interleukin 2 receptor, alpha chain	0.014
Aqp7	aquaporin 7	0.014
Cfd	complement factor D (adipsin)	0.014	Mouse
Kera	keratocan	0.014
Cd86	CD86 antigen	0.014
Rpl39l	ribosomal protein L39-like	0.014
Slamf8	SLAM family member 8	0.014
C1qtnf1	C1q and tumor necrosis factor related protein 1	0.014
Klra17	killer cell lectin-like receptor, subfamily A, member 17	0.014
Mup4	major urinary protein 4	0.014
Traf1	TNF receptor-associated factor 1	0.014
Cd8a	CD8 antigen, alpha chain	0.013
Apoc2	apolipoprotein C-II	0.013
Itih4	inter alpha-trypsin inhibitor, heavy chain 4	0.013
Hc	hemolytic complement	0.013
Cd177	CD177 antigen	0.013
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.013
Glrp1	glutamine repeat protein 1	0.013
Ces1c	carboxylesterase 1C	0.013
Tal1	T-cell acute lymphocytic leukemia 1	0.013
Epx	eosinophil peroxidase	0.013
Irf7	interferon regulatory factor 7	0.012
Cxcl3	chemokine (C-X-C motif) ligand 3	0.012
Chrna1	cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)	0.012
Masp1	mannan-binding lectin serine peptidase 1	0.012
Ermap	erythroblast membrane-associated protein	0.012
Il18r1	interleukin 18 receptor 1	0.012
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.012
Reg3g	regenerating islet-derived 3 gamma	0.012
Cmklr1	chemokine-like receptor 1	0.012
Gfi1	growth factor independent 1	0.012
Tnfsf10	tumor necrosis factor (ligand) superfamily, member 10	0.012
Gzmg	granzyme G	0.012	Mouse
Lrg1	leucine-rich alpha-2-glycoprotein 1	0.012
Sh2d1b1	SH2 domain protein 1B1	0.012
Tfpi2	tissue factor pathway inhibitor 2	0.012
Vpreb1	pre-B lymphocyte gene 1	0.012
Trem1	triggering receptor expressed on myeloid cells 1	0.012
Gp9	glycoprotein 9 (platelet)	0.012
Tnfsf4	tumor necrosis factor (ligand) superfamily, member 4	0.011
Rgs1	regulator of G-protein signaling 1	0.011
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.011
Ccbp2	chemokine binding protein 2	0.011
Serpinb2	serine (or cysteine) peptidase inhibitor, clade B, member 2	0.011
Mcpt1	mast cell protease 1	0.011	Mouse
Klk1b26	kallikrein 1-related petidase b26	0.011
Fos	FBJ osteosarcoma oncogene	0.011
Mmp3	matrix metallopeptidase 3	0.011
Gzma	granzyme A	0.011	Mouse
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.011
Sprr2h	small proline-rich protein 2H	0.011
Slc7a11	solute carrier family 7 (cationic amino acid transporter, y+ system), member 11	0.011
Itgam	integrin alpha M	0.011
Lilrb3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.011
Adrb3	adrenergic receptor, beta 3	0.011
Ceacam10	carcinoembryonic antigen-related cell adhesion molecule 10	0.010
Muc1	mucin 1, transmembrane	0.010
Gbp7	guanylate binding protein 7	0.010
Oas3	2'-5' oligoadenylate synthetase 3	0.010
Try5	trypsin 5	0.010
Serpina3c	serine (or cysteine) peptidase inhibitor, clade A, member 3C	0.010
Cela1	chymotrypsin-like elastase family, member 1	0.010
Sele	selectin, endothelial cell	0.010
Spry4	sprouty homolog 4 (Drosophila)	0.010