Mus musculus

121 known processes

Nipbl

Nipped-B homolog (Drosophila)

(Aliases: C79399,4933421G18Rik,4921518A06Rik,Idn3)

Nipbl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
covalent chromatin modification GO:0016569 163 0.741
Human
histone methylation GO:0016571 71 0.441
cellular response to dna damage stimulus GO:0006974 207 0.436
Human
chromatin silencing GO:0006342 15 0.322
dna metabolic process GO:0006259 303 0.297
histone modification GO:0016570 159 0.265
Human
macromolecule methylation GO:0043414 120 0.209
methylation GO:0032259 134 0.205
histone lysine methylation GO:0034968 50 0.190
protein alkylation GO:0008213 81 0.162
protein methylation GO:0006479 81 0.137
gene silencing GO:0016458 38 0.113
negative regulation of chromatin silencing GO:0031936 1 0.110
histone h3 k4 trimethylation GO:0080182 5 0.110
mrna metabolic process GO:0016071 84 0.106
multicellular organism growth GO:0035264 161 0.099
peptidyl lysine methylation GO:0018022 29 0.097
chromatin organization GO:0006325 206 0.093
Human
stem cell fate specification GO:0048866 3 0.085
chromatin modification GO:0016568 187 0.080
Human
histone h3 k9 methylation GO:0051567 17 0.080
regulation of chromatin silencing GO:0031935 2 0.078
cellular ketone metabolic process GO:0042180 84 0.076
histone h3 k4 methylation GO:0051568 23 0.076
rna processing GO:0006396 105 0.069
dna methylation GO:0006306 43 0.068
ribonucleoprotein complex subunit organization GO:0071826 28 0.068
leukocyte differentiation GO:0002521 342 0.062
intracellular receptor signaling pathway GO:0030522 74 0.062
dna recombination GO:0006310 92 0.061
spermatogenesis GO:0007283 284 0.058
cell cycle checkpoint GO:0000075 47 0.055
digestive system development GO:0055123 200 0.054
Human
epithelial cell development GO:0002064 159 0.054
male gamete generation GO:0048232 285 0.050
regulation of mapk cascade GO:0043408 248 0.049
regulation of chromosome organization GO:0033044 83 0.047
Human
histone h3 k9 trimethylation GO:0036124 6 0.046
cellular amino acid metabolic process GO:0006520 103 0.046
apoptotic signaling pathway GO:0097190 306 0.046
regulation of gene silencing GO:0060968 7 0.045
dna integrity checkpoint GO:0031570 28 0.044
dna repair GO:0006281 107 0.043
posttranscriptional regulation of gene expression GO:0010608 155 0.042
positive regulation of protein modification process GO:0031401 299 0.042
Human
organic cyclic compound catabolic process GO:1901361 295 0.041
cellular response to lipid GO:0071396 145 0.040
peptidyl lysine modification GO:0018205 77 0.039
stem cell maintenance GO:0019827 130 0.038
i kappab kinase nf kappab signaling GO:0007249 85 0.036
protein acylation GO:0043543 64 0.036
macromolecule catabolic process GO:0009057 281 0.036
positive regulation of histone h3 k9 methylation GO:0051574 4 0.036
regulation of cellular amino acid metabolic process GO:0006521 5 0.036
positive regulation of cellular amine metabolic process GO:0033240 5 0.035
leukocyte mediated immunity GO:0002443 174 0.035
blastocyst development GO:0001824 80 0.035
cellular macromolecule catabolic process GO:0044265 206 0.033
digestive tract development GO:0048565 190 0.033
Human
negative regulation of protein metabolic process GO:0051248 282 0.033
actin mediated cell contraction GO:0070252 15 0.033
nucleosome positioning GO:0016584 4 0.032
immune effector process GO:0002252 321 0.032
homeostasis of number of cells GO:0048872 210 0.032
regulation of protein stability GO:0031647 52 0.031
neural tube development GO:0021915 160 0.031
mapk cascade GO:0000165 281 0.031
regulation of system process GO:0044057 200 0.030
regulation of histone modification GO:0031056 56 0.030
Human
cytoplasmic mrna processing body assembly GO:0033962 6 0.029
regulation of histone h3 k9 methylation GO:0051570 8 0.028
protein dna complex subunit organization GO:0071824 28 0.028
multi multicellular organism process GO:0044706 109 0.028
multi organism reproductive behavior GO:0044705 29 0.028
negative regulation of cellular protein metabolic process GO:0032269 247 0.027
negative regulation of gene expression epigenetic GO:0045814 15 0.026
regulation of jak stat cascade GO:0046425 34 0.026
compound eye development GO:0048749 1 0.025
epithalamus development GO:0021538 2 0.024
peptidyl amino acid modification GO:0018193 336 0.024
heterocycle catabolic process GO:0046700 280 0.023
regulation of rna export from nucleus GO:0046831 4 0.023
nuclear transcribed mrna catabolic process GO:0000956 16 0.022
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.022
small gtpase mediated signal transduction GO:0007264 97 0.022
rna catabolic process GO:0006401 29 0.022
regulation of cell motility GO:2000145 236 0.021
stem cell development GO:0048864 219 0.021
respiratory system development GO:0060541 190 0.021
nucleic acid phosphodiester bond hydrolysis GO:0090305 49 0.021
amine metabolic process GO:0009308 45 0.020
gonad development GO:0008406 141 0.020
protein modification by small protein conjugation or removal GO:0070647 207 0.020
regulation of cell cycle phase transition GO:1901987 77 0.020
lung development GO:0030324 164 0.020
regulation of cell migration GO:0030334 219 0.020
dna damage checkpoint GO:0000077 26 0.020
central nervous system projection neuron axonogenesis GO:0021952 21 0.019
male sex differentiation GO:0046661 109 0.019
regulation of ras protein signal transduction GO:0046578 114 0.019
central nervous system neuron differentiation GO:0021953 162 0.019
negative regulation of vasculature development GO:1901343 26 0.019
regulation of response to wounding GO:1903034 189 0.019
endocytosis GO:0006897 168 0.019
multicellular organismal reproductive behavior GO:0033057 23 0.019
regulation of kinase activity GO:0043549 249 0.019
regulation of chromatin modification GO:1903308 57 0.018
Human
regulation of gene expression by genetic imprinting GO:0006349 15 0.018
regulation of cellular response to stress GO:0080135 159 0.018
rna interference GO:0016246 2 0.018
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.018
male gonad development GO:0008584 88 0.018
regulation of defense response GO:0031347 233 0.018
gene silencing by mirna GO:0035195 10 0.018
myeloid cell differentiation GO:0030099 233 0.018
purine nucleoside triphosphate metabolic process GO:0009144 226 0.017
negative regulation of bmp signaling pathway GO:0030514 35 0.017
negative regulation of phosphorylation GO:0042326 166 0.017
negative regulation of gene silencing GO:0060969 2 0.017
regulation of rna splicing GO:0043484 37 0.017
regulation of organelle organization GO:0033043 289 0.017
Human
regulation of adaptive immune response GO:0002819 90 0.017
habenula development GO:0021986 2 0.017
chromatin silencing at rdna GO:0000183 3 0.017
rna phosphodiester bond hydrolysis GO:0090501 19 0.017
regulation of cellular ketone metabolic process GO:0010565 66 0.017
purine ribonucleotide catabolic process GO:0009154 208 0.016
t cell activation GO:0042110 289 0.016
heart morphogenesis GO:0003007 178 0.016
Human
rab protein signal transduction GO:0032482 1 0.016
oogenesis GO:0048477 56 0.016
positive regulation of protein phosphorylation GO:0001934 242 0.016
negative regulation of phosphorus metabolic process GO:0010563 184 0.016
chromosome organization involved in meiosis GO:0070192 39 0.016
negative regulation of immune system process GO:0002683 209 0.016
blood vessel morphogenesis GO:0048514 285 0.016
organonitrogen compound catabolic process GO:1901565 264 0.015
posttranscriptional gene silencing GO:0016441 10 0.015
germ cell development GO:0007281 185 0.015
organelle assembly GO:0070925 177 0.015
cerebellar purkinje cell layer morphogenesis GO:0021692 14 0.015
nucleobase containing small molecule metabolic process GO:0055086 352 0.015
multi organism behavior GO:0051705 62 0.015
regulation of chromatin organization GO:1902275 57 0.015
Human
protein dealkylation GO:0008214 13 0.015
ribonucleoside monophosphate metabolic process GO:0009161 80 0.014
histone h3 k9 dimethylation GO:0036123 4 0.014
development of primary sexual characteristics GO:0045137 143 0.014
histone h3 k36 demethylation GO:0070544 2 0.014
mitotic sister chromatid cohesion GO:0007064 1 0.014
Human
histone h4 k20 methylation GO:0034770 8 0.014
negative regulation of cell cycle GO:0045786 123 0.014
chromatin mediated maintenance of transcription GO:0048096 2 0.013
dna modification GO:0006304 50 0.013
limb development GO:0060173 166 0.013
Human
dna alkylation GO:0006305 43 0.013
hematopoietic progenitor cell differentiation GO:0002244 143 0.013
extrinsic apoptotic signaling pathway GO:0097191 126 0.013
cell division GO:0051301 120 0.013
indole containing compound metabolic process GO:0042430 12 0.012
aromatic compound catabolic process GO:0019439 286 0.012
negative regulation of mitotic cell cycle GO:0045930 58 0.012
adaptive immune response GO:0002250 155 0.012
neuron projection guidance GO:0097485 141 0.012
negative regulation of cellular component organization GO:0051129 194 0.012
mrna catabolic process GO:0006402 22 0.012
microtubule cytoskeleton organization GO:0000226 157 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.012
mrna processing GO:0006397 63 0.012
cellular nitrogen compound catabolic process GO:0044270 280 0.012
peptidyl lysine acetylation GO:0018394 45 0.012
dendrite development GO:0016358 115 0.011
regulation of platelet derived growth factor receptor alpha signaling pathway GO:2000583 2 0.011
myeloid leukocyte mediated immunity GO:0002444 42 0.011
protein modification by small protein conjugation GO:0032446 187 0.011
ribose phosphate metabolic process GO:0019693 291 0.011
negative regulation of germinal center formation GO:0002635 2 0.011
gene silencing by rna GO:0031047 19 0.011
regulation of innate immune response GO:0045088 91 0.011
multinuclear osteoclast differentiation GO:0072674 4 0.011
purine nucleoside monophosphate metabolic process GO:0009126 81 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 57 0.011
negative regulation of pancreatic juice secretion GO:0090188 3 0.011
negative regulation of proteolysis GO:0045861 74 0.011
body morphogenesis GO:0010171 45 0.011
Human
regulation of hydrolase activity GO:0051336 246 0.011
regulation of mrna processing GO:0050684 41 0.010
somitogenesis GO:0001756 69 0.010
feeding behavior GO:0007631 62 0.010
chromatin assembly GO:0031497 13 0.010
regulation of viral transcription GO:0046782 3 0.010
negative regulation of phosphate metabolic process GO:0045936 184 0.010
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 22 0.010
axon guidance GO:0007411 141 0.010
morphogenesis of an endothelium GO:0003159 2 0.010
regulation of transcription by chromatin organization GO:0034401 0 0.010
epithelial cell morphogenesis GO:0003382 41 0.010
somite development GO:0061053 81 0.010

Nipbl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.064
organ system cancer DOID:0050686 0 0.064
cancer DOID:162 0 0.064
disease of anatomical entity DOID:7 0 0.012
nervous system disease DOID:863 0 0.012