Mus musculus

0 known processes

Ins1

insulin I

(Aliases: Ins2-rs1,Ins-1)

Ins1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
proteoglycan biosynthetic process GO:0030166 20 0.642
Mouse
cellular amino acid metabolic process GO:0006520 103 0.584
amine metabolic process GO:0009308 45 0.560
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.542
sulfur compound metabolic process GO:0006790 100 0.446
Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.392
apoptotic signaling pathway GO:0097190 306 0.381
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.340
cellular amine metabolic process GO:0044106 44 0.280
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.269
Mouse
epithelial tube morphogenesis GO:0060562 303 0.261
Mouse
urogenital system development GO:0001655 261 0.254
Mouse
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.234
type ii pneumocyte differentiation GO:0060510 7 0.223
Mouse
cation transport GO:0006812 399 0.220
regulation of cellular amino acid metabolic process GO:0006521 5 0.220
exocrine pancreas development GO:0031017 7 0.216
Mouse
peptidyl tyrosine modification GO:0018212 145 0.196
Mouse
wnt signaling pathway GO:0016055 188 0.189
Mouse
cytokine mediated signaling pathway GO:0019221 115 0.188
muscle cell differentiation GO:0042692 261 0.183
Mouse
regulation of glycogen metabolic process GO:0070873 13 0.177
Mouse
regulation of defense response GO:0031347 233 0.175
inflammatory response GO:0006954 244 0.166
cation transmembrane transport GO:0098655 266 0.157
forebrain development GO:0030900 302 0.148
blood vessel morphogenesis GO:0048514 285 0.145
regulation of response to wounding GO:1903034 189 0.143
extrinsic apoptotic signaling pathway GO:0097191 126 0.141
Mouse
cellular polysaccharide metabolic process GO:0044264 38 0.138
Mouse
chondroitin sulfate proteoglycan biosynthetic process GO:0050650 8 0.136
Mouse
chondroitin sulfate proteoglycan metabolic process GO:0050654 20 0.134
Mouse
cellular glucan metabolic process GO:0006073 32 0.133
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.128
regulation of apoptotic signaling pathway GO:2001233 197 0.126
Mouse
hindbrain development GO:0030902 128 0.126
Mouse
peptidyl tyrosine phosphorylation GO:0018108 143 0.125
Mouse
negative regulation of cell proliferation GO:0008285 296 0.124
Mouse
sodium ion transport GO:0006814 73 0.121
positive regulation of protein phosphorylation GO:0001934 242 0.118
Mouse
digestive system development GO:0055123 200 0.114
Mouse
anatomical structure homeostasis GO:0060249 145 0.109
pancreas development GO:0031016 57 0.108
Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.106
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.104
Mouse
respiratory tube development GO:0030323 167 0.102
Mouse
regulation of inflammatory response GO:0050727 147 0.102
transmembrane transport GO:0055085 412 0.101
regulation of metal ion transport GO:0010959 106 0.100
chondrocyte differentiation GO:0002062 72 0.100
intrinsic apoptotic signaling pathway GO:0097193 132 0.099
Mouse
synaptic transmission GO:0007268 329 0.098
myosin filament assembly GO:0031034 2 0.098
negative regulation of protein metabolic process GO:0051248 282 0.097
cellular ketone metabolic process GO:0042180 84 0.094
regulation of feeding behavior GO:0060259 3 0.090
Zebrafish
positive regulation of nervous system development GO:0051962 221 0.089
Mouse
generation of precursor metabolites and energy GO:0006091 103 0.088
Mouse
regulation of androgen receptor signaling pathway GO:0060765 3 0.087
Mouse
nucleotide metabolic process GO:0009117 332 0.086
mitochondrion organization GO:0007005 134 0.085
Mouse
response to growth factor GO:0070848 198 0.084
negative regulation of phosphorylation GO:0042326 166 0.082
Mouse
release of cytochrome c from mitochondria GO:0001836 23 0.082
Mouse
polysaccharide metabolic process GO:0005976 39 0.081
Mouse
sensory perception GO:0007600 245 0.081
connective tissue development GO:0061448 179 0.081
Mouse
response to extracellular stimulus GO:0009991 127 0.081
Zebrafish
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.079
Mouse
positive regulation of cell development GO:0010720 237 0.078
angiogenesis GO:0001525 201 0.076
gland development GO:0048732 330 0.075
Mouse
regulation of kinase activity GO:0043549 249 0.075
Mouse
inorganic ion transmembrane transport GO:0098660 234 0.075
regulation of protein serine threonine kinase activity GO:0071900 157 0.075
Mouse
response to monosaccharide GO:0034284 67 0.074
Zebrafish
purine nucleotide catabolic process GO:0006195 211 0.073
regulation of anatomical structure size GO:0090066 178 0.072
glucan metabolic process GO:0044042 32 0.071
Mouse
purine containing compound metabolic process GO:0072521 311 0.069
diencephalon development GO:0021536 63 0.068
glycoprotein biosynthetic process GO:0009101 89 0.067
Mouse
spermatogenesis GO:0007283 284 0.065
defense response to bacterium GO:0042742 119 0.065
regulation of cytokine production GO:0001817 266 0.065
intracellular receptor signaling pathway GO:0030522 74 0.064
Mouse
cytokine production GO:0001816 319 0.063
negative regulation of intracellular signal transduction GO:1902532 167 0.062
Mouse
positive regulation of protein modification process GO:0031401 299 0.062
Mouse
apoptotic mitochondrial changes GO:0008637 48 0.062
Mouse
regulation of gastric acid secretion GO:0060453 2 0.062
regulation of protein kinase activity GO:0045859 232 0.061
Mouse
cell fate commitment GO:0045165 210 0.060
fatty acid metabolic process GO:0006631 121 0.059
negative regulation of cellular protein metabolic process GO:0032269 247 0.059
peptidyl amino acid modification GO:0018193 336 0.058
Mouse
striated muscle tissue development GO:0014706 293 0.058
positive regulation of glycogen starch synthase activity GO:2000467 4 0.058
Mouse
prostate gland growth GO:0060736 13 0.058
Mouse
respiratory system development GO:0060541 190 0.056
Mouse
exocrine system development GO:0035272 45 0.056
Mouse
regulation of polysaccharide metabolic process GO:0032881 13 0.056
Mouse
myeloid cell differentiation GO:0030099 233 0.055
striated muscle contraction GO:0006941 45 0.054
regulation of glycogen starch synthase activity GO:2000465 5 0.054
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.054
positive regulation of catecholamine secretion GO:0033605 2 0.051
regulation of cellular ketone metabolic process GO:0010565 66 0.050
cellular response to growth factor stimulus GO:0071363 197 0.050
glucose homeostasis GO:0042593 128 0.049
regionalization GO:0003002 337 0.049
regulation of secretion GO:0051046 274 0.049
lung cell differentiation GO:0060479 30 0.049
Mouse
negative regulation of cellular amine metabolic process GO:0033239 1 0.048
cardiocyte differentiation GO:0035051 87 0.048
negative regulation of androgen receptor signaling pathway GO:0060766 3 0.047
Mouse
myeloid leukocyte activation GO:0002274 83 0.047
glycoprotein metabolic process GO:0009100 116 0.047
Mouse
muscle contraction GO:0006936 101 0.047
cellular response to organonitrogen compound GO:0071417 145 0.047
Mouse
striated muscle cell development GO:0055002 125 0.046
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.045
positive regulation of peptide hormone secretion GO:0090277 31 0.045
proteoglycan metabolic process GO:0006029 38 0.045
Mouse
response to light stimulus GO:0009416 135 0.044
negative regulation of epidermal cell differentiation GO:0045605 7 0.044
lipid transport GO:0006869 98 0.044
positive regulation of secretion by cell GO:1903532 114 0.044
multicellular organismal homeostasis GO:0048871 164 0.044
regulation of tube size GO:0035150 57 0.044
smoothened signaling pathway GO:0007224 105 0.044
lipid catabolic process GO:0016042 69 0.043
Mouse
regulation of vasculature development GO:1901342 88 0.043
ribose phosphate metabolic process GO:0019693 291 0.043
regulation of cell cycle GO:0051726 281 0.043
negative regulation of keratinocyte differentiation GO:0045617 4 0.043
myotube differentiation GO:0014902 105 0.043
Mouse
lipid localization GO:0010876 126 0.042
baroreceptor response to decreased systemic arterial blood pressure GO:0001982 2 0.042
organonitrogen compound biosynthetic process GO:1901566 192 0.042
Mouse
positive regulation of keratinocyte proliferation GO:0010838 4 0.042
defense response to gram positive bacterium GO:0050830 50 0.041
negative regulation of protein modification process GO:0031400 163 0.041
protein oligomerization GO:0051259 67 0.040
sensory perception of light stimulus GO:0050953 54 0.040
purine nucleotide metabolic process GO:0006163 302 0.040
negative regulation of release of cytochrome c from mitochondria GO:0090201 6 0.040
Mouse
glycogen metabolic process GO:0005977 32 0.040
Mouse
keratinocyte differentiation GO:0030216 48 0.039
protein maturation GO:0051604 176 0.039
telencephalon development GO:0021537 186 0.039
divalent metal ion transport GO:0070838 172 0.039
l alpha amino acid transmembrane transport GO:1902475 23 0.039
neural nucleus development GO:0048857 22 0.039
negative regulation of macrophage activation GO:0043031 2 0.039
negative regulation of protein phosphorylation GO:0001933 126 0.039
ear development GO:0043583 200 0.039
Mouse
regulation of lymphocyte proliferation GO:0050670 117 0.038
regulation of angiogenesis GO:0045765 81 0.038
glycosaminoglycan metabolic process GO:0030203 34 0.038
Mouse
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.037
Mouse
circulatory system process GO:0003013 197 0.037
visual perception GO:0007601 52 0.037
negative regulation of leukocyte differentiation GO:1902106 51 0.036
response to inorganic substance GO:0010035 96 0.036
regulation of leukocyte proliferation GO:0070663 121 0.036
regulation of t cell activation GO:0050863 170 0.036
camera type eye development GO:0043010 266 0.036
skeletal muscle organ development GO:0060538 163 0.036
regulation of glucose metabolic process GO:0010906 60 0.036
Mouse
regulation of body fluid levels GO:0050878 162 0.036
prostate gland development GO:0030850 48 0.036
Mouse
cellular response to biotic stimulus GO:0071216 92 0.036
Mouse
organ growth GO:0035265 117 0.036
Mouse
positive regulation of secretion GO:0051047 130 0.036
cellular divalent inorganic cation homeostasis GO:0072503 127 0.035
negative regulation of cytokine production GO:0001818 84 0.035
regulation of generation of precursor metabolites and energy GO:0043467 38 0.035
Mouse
regulation of ion transport GO:0043269 215 0.035
regulation of organ growth GO:0046620 61 0.035
anion transmembrane transport GO:0098656 71 0.035
sensory perception of sound GO:0007605 97 0.035
leukocyte migration GO:0050900 124 0.034
regulation of cell activation GO:0050865 289 0.034
organelle assembly GO:0070925 177 0.034
cellular response to cytokine stimulus GO:0071345 189 0.034
negative regulation of apoptotic signaling pathway GO:2001234 104 0.034
Mouse
insulin receptor signaling pathway via phosphatidylinositol 3 kinase GO:0038028 3 0.034
Mouse
positive regulation of renal sodium excretion GO:0035815 2 0.034
negative regulation of phosphate metabolic process GO:0045936 184 0.033
Mouse
regulation of keratinocyte differentiation GO:0045616 11 0.033
glial cell differentiation GO:0010001 131 0.033
Mouse
regulation of heart contraction GO:0008016 77 0.033
carbohydrate metabolic process GO:0005975 230 0.033
Mouse
regulation of ion transmembrane transport GO:0034765 119 0.033
negative regulation of mapk cascade GO:0043409 65 0.032
Mouse
response to insulin GO:0032868 100 0.032
Mouse
cell substrate adhesion GO:0031589 130 0.032
carbohydrate homeostasis GO:0033500 128 0.032
myeloid leukocyte differentiation GO:0002573 119 0.032
syncytium formation GO:0006949 43 0.032
Mouse
response to radiation GO:0009314 165 0.032
cell maturation GO:0048469 127 0.032
regulation of organelle organization GO:0033043 289 0.031
Mouse
regulation of transferase activity GO:0051338 263 0.030
Mouse
regulation of lymphocyte activation GO:0051249 240 0.030
cellular response to abiotic stimulus GO:0071214 56 0.030
organophosphate catabolic process GO:0046434 232 0.030
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 18 0.030
reactive oxygen species metabolic process GO:0072593 84 0.030
positive regulation of dopamine secretion GO:0033603 2 0.030
adult behavior GO:0030534 135 0.030
morphogenesis of a branching structure GO:0001763 203 0.030
Mouse
regulation of cell motility GO:2000145 236 0.030
lipid homeostasis GO:0055088 63 0.030
insulin secretion GO:0030073 89 0.030
acetylcholine secretion neurotransmission GO:0014055 2 0.030
positive regulation of glycogen metabolic process GO:0070875 8 0.029
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.029
negative regulation of growth GO:0045926 99 0.029
ribonucleoside metabolic process GO:0009119 245 0.029
neural precursor cell proliferation GO:0061351 121 0.029
Mouse
spinal cord oligodendrocyte cell differentiation GO:0021529 3 0.029
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.028
nucleoside monophosphate metabolic process GO:0009123 85 0.028
regulation of blood pressure GO:0008217 93 0.028
prostate gland morphogenesis GO:0060512 32 0.028
Mouse
regulation of smoothened signaling pathway GO:0008589 58 0.028
ribonucleotide metabolic process GO:0009259 291 0.028
regulation of neuron death GO:1901214 134 0.028
signal transduction in absence of ligand GO:0038034 55 0.028
Mouse
transition metal ion transport GO:0000041 38 0.028
extracellular matrix organization GO:0030198 147 0.027
regulation of purine nucleotide metabolic process GO:1900542 169 0.027
hemostasis GO:0007599 78 0.027
intermediate filament based process GO:0045103 27 0.027
tissue homeostasis GO:0001894 115 0.027
mapk cascade GO:0000165 281 0.027
Mouse
heart contraction GO:0060047 93 0.027
cerebellar granule cell precursor proliferation GO:0021930 10 0.027
Mouse
nucleoside triphosphate metabolic process GO:0009141 230 0.027
ribonucleoside triphosphate metabolic process GO:0009199 220 0.027
multi multicellular organism process GO:0044706 109 0.026
positive regulation of cell activation GO:0050867 158 0.026
positive regulation of transferase activity GO:0051347 167 0.026
Mouse
regulation of lipid metabolic process GO:0019216 118 0.026
Mouse
cell chemotaxis GO:0060326 81 0.026
organic hydroxy compound metabolic process GO:1901615 203 0.026
cytoplasmic transport GO:0016482 234 0.026
response to endoplasmic reticulum stress GO:0034976 53 0.026
Mouse
homeostasis of number of cells GO:0048872 210 0.026
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.026
Mouse
learning or memory GO:0007611 148 0.026
macromolecule catabolic process GO:0009057 281 0.026
cell differentiation in spinal cord GO:0021515 53 0.026
positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure GO:0001988 1 0.026
purine nucleoside metabolic process GO:0042278 241 0.025
organic anion transport GO:0015711 137 0.025
response to nutrient levels GO:0031667 109 0.025
Zebrafish
negative regulation of cell activation GO:0050866 111 0.025
response to peptide hormone GO:0043434 127 0.025
Mouse Rat
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.025
macrophage activation GO:0042116 27 0.025
i kappab kinase nf kappab signaling GO:0007249 85 0.025
response to organonitrogen compound GO:0010243 246 0.025
Mouse Rat
positive regulation of mapk cascade GO:0043410 170 0.025
Mouse
glycogen biosynthetic process GO:0005978 14 0.025
Mouse
rhythmic process GO:0048511 174 0.025
Mouse
male gamete generation GO:0048232 285 0.025
ribose phosphate biosynthetic process GO:0046390 59 0.025
negative regulation of action potential GO:0045759 1 0.024
calcium ion transport into cytosol GO:0060402 48 0.024
positive regulation of leukocyte proliferation GO:0070665 73 0.024
regulation of neurotransmitter levels GO:0001505 87 0.024
glycosaminoglycan biosynthetic process GO:0006024 15 0.024
Mouse
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.024
pancreatic a cell fate commitment GO:0003326 2 0.024
regulation of transmembrane transport GO:0034762 128 0.024
kidney development GO:0001822 213 0.024
atp metabolic process GO:0046034 75 0.024
germ cell development GO:0007281 185 0.024
muscle cell development GO:0055001 133 0.024
regulation of ion homeostasis GO:2000021 64 0.024
t cell differentiation GO:0030217 174 0.024
negative regulation of mitochondrion organization GO:0010823 9 0.023
Mouse
regulation of circadian rhythm GO:0042752 58 0.023
pituitary gland development GO:0021983 38 0.023
regulation of circadian sleep wake cycle rem sleep GO:0042320 1 0.023
defense response to other organism GO:0098542 197 0.023
negative regulation of phosphorus metabolic process GO:0010563 184 0.023
Mouse
synaptic transmission involved in micturition GO:0060084 3 0.023
oxidation reduction process GO:0055114 342 0.023
Mouse
embryonic placenta development GO:0001892 98 0.023
regulation of epidermis development GO:0045682 33 0.023
nucleotide catabolic process GO:0009166 217 0.023
myosin filament organization GO:0031033 3 0.023
cell activation involved in immune response GO:0002263 126 0.023
negative regulation of molecular function GO:0044092 258 0.023
fat cell differentiation GO:0045444 160 0.023
calcium ion transport GO:0006816 159 0.022
intracellular protein transport GO:0006886 204 0.022
regulation of macrophage activation GO:0043030 17 0.022
regulation of homeostatic process GO:0032844 182 0.022
tube formation GO:0035148 140 0.022
microglial cell activation involved in immune response GO:0002282 1 0.022
canonical wnt signaling pathway GO:0060070 130 0.022
Mouse
blood coagulation GO:0007596 76 0.021
epithelial cell development GO:0002064 159 0.021
regulation of water loss via skin GO:0033561 16 0.021
spinal cord development GO:0021510 81 0.021
glycosyl compound metabolic process GO:1901657 246 0.021
dendrite development GO:0016358 115 0.021
purine containing compound biosynthetic process GO:0072522 70 0.021
tissue migration GO:0090130 68 0.021
small gtpase mediated signal transduction GO:0007264 97 0.021
negative regulation of sterol transport GO:0032372 4 0.021
ear morphogenesis GO:0042471 118 0.021
negative regulation of immune effector process GO:0002698 55 0.021
positive regulation of insulin secretion GO:0032024 26 0.021
aminoglycan metabolic process GO:0006022 34 0.020
Mouse
regulation of binding GO:0051098 111 0.020
Mouse
negative regulation of blood vessel morphogenesis GO:2000181 25 0.020
regulation of systemic arterial blood pressure GO:0003073 61 0.020
sodium ion transmembrane transport GO:0035725 49 0.020
positive regulation of angiogenesis GO:0045766 46 0.020
positive regulation of ion transport GO:0043270 65 0.020
muscle system process GO:0003012 141 0.020
endocrine system development GO:0035270 98 0.020
posttranscriptional regulation of gene expression GO:0010608 155 0.020
erk1 and erk2 cascade GO:0070371 77 0.020
Mouse
neural tube development GO:0021915 160 0.020
negative regulation of cell development GO:0010721 169 0.020
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.020
acetylcholine transport GO:0015870 2 0.020
cholesterol homeostasis GO:0042632 44 0.020
positive regulation of blood pressure GO:0045777 21 0.020
purine nucleoside triphosphate metabolic process GO:0009144 226 0.020
negative regulation of intracellular steroid hormone receptor signaling pathway GO:0033144 11 0.019
Mouse
regulation of intracellular transport GO:0032386 159 0.019
positive regulation of t cell activation GO:0050870 101 0.019
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.019
negative regulation of epidermis development GO:0045683 9 0.019
regulation of mapk cascade GO:0043408 248 0.019
Mouse
alanine transport GO:0032328 4 0.019
carboxylic acid biosynthetic process GO:0046394 86 0.019
hematopoietic progenitor cell differentiation GO:0002244 143 0.019
regulation of interferon gamma production GO:0032649 57 0.019
cognition GO:0050890 149 0.019
prostate gland epithelium morphogenesis GO:0060740 31 0.018
Mouse
purine ribonucleoside catabolic process GO:0046130 205 0.018
monosaccharide transport GO:0015749 58 0.018
endocrine process GO:0050886 39 0.018
positive regulation of homeostatic process GO:0032846 64 0.018
lymphocyte differentiation GO:0030098 242 0.018
regulation of monocyte chemotaxis GO:0090025 3 0.018
negative regulation of response to wounding GO:1903035 77 0.018
inorganic cation transmembrane transport GO:0098662 207 0.018
intermediate filament cytoskeleton organization GO:0045104 26 0.018
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.018
negative regulation of defense response GO:0031348 77 0.018
positive regulation of neuron differentiation GO:0045666 141 0.018
lung epithelium development GO:0060428 37 0.018
Mouse
muscle tissue development GO:0060537 308 0.018
embryonic epithelial tube formation GO:0001838 130 0.018
heterocycle catabolic process GO:0046700 280 0.018
feeding behavior GO:0007631 62 0.018
Zebrafish
nitrogen compound transport GO:0071705 271 0.018
cell type specific apoptotic process GO:0097285 268 0.017
aminoglycan biosynthetic process GO:0006023 15 0.017
Mouse
sterol homeostasis GO:0055092 45 0.017
organic cyclic compound catabolic process GO:1901361 295 0.017
positive regulation of response to wounding GO:1903036 66 0.017
positive regulation of cytokine production GO:0001819 174 0.017
cardiac muscle cell differentiation GO:0055007 69 0.017
syncytium formation by plasma membrane fusion GO:0000768 42 0.017
Mouse
lateral geniculate nucleus development GO:0021771 1 0.017
developmental maturation GO:0021700 193 0.017
sterol metabolic process GO:0016125 58 0.017
lung lobe morphogenesis GO:0060463 9 0.017
Mouse
phagocytosis GO:0006909 66 0.017
sensory organ morphogenesis GO:0090596 242 0.017
divalent inorganic cation transport GO:0072511 178 0.017
negative regulation of inflammatory response GO:0050728 61 0.017
regulation of cell adhesion GO:0030155 154 0.017
purine containing compound catabolic process GO:0072523 213 0.017
regulation of epidermal cell differentiation GO:0045604 21 0.017
regulation of digestive system process GO:0044058 13 0.016
embryonic organ morphogenesis GO:0048562 276 0.016
monocarboxylic acid metabolic process GO:0032787 191 0.016
lung lobe development GO:0060462 9 0.016
Mouse
acetate ester transport GO:1901374 2 0.016
nucleotide biosynthetic process GO:0009165 78 0.016
coagulation GO:0050817 78 0.016
cartilage development GO:0051216 140 0.016
protein processing GO:0016485 163 0.016
chemokine mediated signaling pathway GO:0070098 17 0.016
ribonucleoside monophosphate metabolic process GO:0009161 80 0.016
cellular lipid metabolic process GO:0044255 323 0.016
Mouse
positive regulation of monocyte extravasation GO:2000439 1 0.016
memory GO:0007613 58 0.016
negative regulation of erk1 and erk2 cascade GO:0070373 21 0.016
Mouse
protein localization to organelle GO:0033365 185 0.016
chondrocyte development GO:0002063 24 0.016
purine ribonucleotide metabolic process GO:0009150 290 0.016
medulla oblongata development GO:0021550 3 0.016
ribonucleotide catabolic process GO:0009261 208 0.016
positive regulation of cerebellar granule cell precursor proliferation GO:0021940 10 0.016
Mouse
sequestering of calcium ion GO:0051208 18 0.016
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.016
cerebral cortex development GO:0021987 86 0.016
visual learning GO:0008542 44 0.016
nucleoside phosphate catabolic process GO:1901292 222 0.016
branching morphogenesis of an epithelial tube GO:0048754 159 0.015
Mouse
organelle localization GO:0051640 179 0.015
response to lipopolysaccharide GO:0032496 128 0.015
regulation of systemic arterial blood pressure by baroreceptor feedback GO:0003025 7 0.015
polysaccharide biosynthetic process GO:0000271 20 0.015
Mouse
carbohydrate biosynthetic process GO:0016051 74 0.015
Mouse
response to ethanol GO:0045471 18 0.015
monosaccharide metabolic process GO:0005996 106 0.015
Mouse
negative regulation of immune system process GO:0002683 209 0.015
nucleoside metabolic process GO:0009116 246 0.015
heart process GO:0003015 94 0.015
positive regulation of neuroblast proliferation GO:0002052 19 0.015
negative regulation of camp mediated signaling GO:0043951 3 0.015
sensory perception of pain GO:0019233 47 0.015
axon guidance GO:0007411 141 0.015
gliogenesis GO:0042063 141 0.015
Mouse
circadian sleep wake cycle rem sleep GO:0042747 1 0.015
regulation of lipid transport GO:0032368 36 0.015
clara cell differentiation GO:0060486 4 0.015
positive regulation of hormone secretion GO:0046887 38 0.015
morphogenesis of a branching epithelium GO:0061138 193 0.015
Mouse
response to organic cyclic compound GO:0014070 198 0.015
Rat
monocarboxylic acid biosynthetic process GO:0072330 61 0.015
hormone metabolic process GO:0042445 86 0.015
hormone secretion GO:0046879 128 0.015
negative regulation of epithelial cell proliferation GO:0050680 64 0.015
establishment of skin barrier GO:0061436 14 0.015
glomerulus development GO:0032835 40 0.015
positive regulation of phospholipase activity GO:0010518 3 0.015
cellular metal ion homeostasis GO:0006875 151 0.015
cellular homeostasis GO:0019725 240 0.015
wound healing GO:0042060 157 0.015
cellular calcium ion homeostasis GO:0006874 119 0.015
anion transport GO:0006820 177 0.015
regulation of protein localization GO:0032880 231 0.015
response to peptide GO:1901652 136 0.015
Mouse Rat
glycosyl compound catabolic process GO:1901658 206 0.015
regulation of system process GO:0044057 200 0.015
organic acid biosynthetic process GO:0016053 86 0.015
extracellular structure organization GO:0043062 148 0.015
regulation of nucleotide metabolic process GO:0006140 169 0.014
microglial cell activation GO:0001774 3 0.014
lung morphogenesis GO:0060425 50 0.014
Mouse
endomembrane system organization GO:0010256 147 0.014
positive regulation of defense response GO:0031349 124 0.014
cellularization GO:0007349 1 0.014
leukocyte activation involved in immune response GO:0002366 126 0.014
aromatic compound catabolic process GO:0019439 286 0.014
ion transmembrane transport GO:0034220 361 0.014
neuron apoptotic process GO:0051402 142 0.014
cell fate determination involved in pattern specification GO:0060582 1 0.014
regulation of mitochondrion organization GO:0010821 27 0.014
Mouse
regulation of muscle tissue development GO:1901861 97 0.014
skeletal system morphogenesis GO:0048705 203 0.014
negative regulation of eosinophil degranulation GO:0043310 1 0.014
bmp signaling pathway GO:0030509 93 0.014
nephron development GO:0072006 109 0.014
photoreceptor cell differentiation GO:0046530 52 0.014
lung secretory cell differentiation GO:0061140 13 0.014
Mouse
negative regulation of cell motility GO:2000146 61 0.014
regulation of protein kinase b signaling GO:0051896 56 0.014
Mouse
response to metal ion GO:0010038 47 0.014
regulation of neural precursor cell proliferation GO:2000177 70 0.014
Mouse
regulation of wnt signaling pathway GO:0030111 123 0.014
regulation of heart growth GO:0060420 31 0.014
metencephalon development GO:0022037 89 0.014
neuron migration GO:0001764 122 0.014
atp catabolic process GO:0006200 55 0.014
cellular component assembly involved in morphogenesis GO:0010927 139 0.014
positive regulation of kinase activity GO:0033674 155 0.013
Mouse
regulation of immunological synapse formation GO:2000520 2 0.013
histone lysine methylation GO:0034968 50 0.013
cell differentiation involved in embryonic placenta development GO:0060706 26 0.013
globus pallidus development GO:0021759 2 0.013
pancreatic pp cell differentiation GO:0003312 2 0.013
ribonucleoside catabolic process GO:0042454 206 0.013
regulation of acetylcholine secretion neurotransmission GO:0014056 2 0.013
cell matrix adhesion GO:0007160 68 0.013

Ins1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.045
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
inherited metabolic disorder DOID:655 0 0.014