IMP
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chondroitin sulfate proteoglycan biosynthetic process
The chemical reactions and pathways resulting in the formation of chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.
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Click on a gene's description to view its network relationships with genes known to be involved in "chondroitin sulfate proteoglycan biosynthetic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Ghr | growth hormone receptor | 0.298 | ||
| Gnas | GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus | 0.279 | ||
| Nos1 | nitric oxide synthase 1, neuronal | 0.243 | ||
| Lepr | leptin receptor | 0.189 | ||
| Cdkn1c | cyclin-dependent kinase inhibitor 1C (P57) | 0.163 | ||
| Npc1 | Niemann Pick type C1 | 0.149 | ||
| Ins1 | insulin I | 0.136 | Mouse | |
| Ins2 | insulin II | 0.127 | Mouse | |
| Grb10 | growth factor receptor bound protein 10 | 0.099 | ||
| Igf2r | insulin-like growth factor 2 receptor | 0.070 | ||
| Kiss1 | KiSS-1 metastasis-suppressor | 0.065 | ||
| Esr1 | estrogen receptor 1 (alpha) | 0.064 | ||
| Insr | insulin receptor | 0.044 | ||
| Adra1b | adrenergic receptor, alpha 1b | 0.043 | ||
| Amhr2 | anti-Mullerian hormone type 2 receptor | 0.036 | ||
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.035 | ||
| Itga1 | integrin alpha 1 | 0.034 | ||
| Irs2 | insulin receptor substrate 2 | 0.028 | ||
| Foxo3 | forkhead box O3 | 0.027 | ||
| Numbl | numb-like | 0.024 | ||
| Prlr | prolactin receptor | 0.022 | ||
| Cyp19a1 | cytochrome P450, family 19, subfamily a, polypeptide 1 | 0.021 | ||
| Ar | androgen receptor | 0.021 | ||
| Vdr | vitamin D receptor | 0.020 | ||
| Tyro3 | TYRO3 protein tyrosine kinase 3 | 0.020 | ||
| Egfr | epidermal growth factor receptor | 0.019 | ||
| B4galt2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 | 0.018 | ||
| Atp8b2 | ATPase, class I, type 8B, member 2 | 0.018 | ||
| Angpt4 | angiopoietin 4 | 0.018 | ||
| Ccdc92 | coiled-coil domain containing 92 | 0.017 | ||
| Nr2f2 | nuclear receptor subfamily 2, group F, member 2 | 0.017 | ||
| Galnt2 | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 | 0.017 | ||
| Bsnd | Bartter syndrome, infantile, with sensorineural deafness (Barttin) | 0.016 | ||
| Ptf1a | pancreas specific transcription factor, 1a | 0.016 | ||
| Abca2 | ATP-binding cassette, sub-family A (ABC1), member 2 | 0.016 | ||
| Glp1r | glucagon-like peptide 1 receptor | 0.015 | ||
| Kl | klotho | 0.015 | ||
| Meis3 | Meis homeobox 3 | 0.015 | ||
| Lep | leptin | 0.014 | ||
| Mogat2 | monoacylglycerol O-acyltransferase 2 | 0.014 | ||
| Cav1 | caveolin 1, caveolae protein | 0.014 | ||
| Gna12 | guanine nucleotide binding protein, alpha 12 | 0.014 | ||
| Krt4 | keratin 4 | 0.014 | ||
| Bglap | bone gamma carboxyglutamate protein | 0.013 | ||
| Rpusd1 | RNA pseudouridylate synthase domain containing 1 | 0.013 | ||
| Akt1 | thymoma viral proto-oncogene 1 | 0.012 | ||
| Nhlh2 | nescient helix loop helix 2 | 0.012 | ||
| Grasp | GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein | 0.012 | ||
| Lrp1 | low density lipoprotein receptor-related protein 1 | 0.012 | ||
| Cacng4 | calcium channel, voltage-dependent, gamma subunit 4 | 0.012 | ||
| Axl | AXL receptor tyrosine kinase | 0.012 | ||
| Nckap5l | NCK-associated protein 5-like | 0.012 | ||
| Praf2 | PRA1 domain family 2 | 0.012 | ||
| Tff2 | trefoil factor 2 (spasmolytic protein 1) | 0.011 | ||
| Plod3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | 0.011 | ||
| Treml1 | triggering receptor expressed on myeloid cells-like 1 | 0.011 | ||
| Esr2 | estrogen receptor 2 (beta) | 0.011 | ||
| Ptprs | protein tyrosine phosphatase, receptor type, S | 0.011 | ||
| Ccdc24 | coiled-coil domain containing 24 | 0.011 | ||
| Arhgap1 | Rho GTPase activating protein 1 | 0.010 | ||
| Pdx1 | pancreatic and duodenal homeobox 1 | 0.010 | ||
| Wdr86 | WD repeat domain 86 | 0.010 |