|
|
positive regulation of jun kinase activity
|
GO:0043507 |
30 |
0.941
|
Human |
|
|
cytokine production involved in immune response
|
GO:0002367 |
34 |
0.914
|
Mouse |
|
|
immune effector process
|
GO:0002252 |
321 |
0.890
|
Mouse |
|
|
regulation of cytokine production
|
GO:0001817 |
266 |
0.888
|
Mouse |
|
|
regulation of secretion
|
GO:0051046 |
274 |
0.877
|
|
|
|
protein secretion
|
GO:0009306 |
111 |
0.866
|
Mouse |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
157 |
0.862
|
Human |
|
|
tissue homeostasis
|
GO:0001894 |
115 |
0.861
|
|
|
|
tissue remodeling
|
GO:0048771 |
102 |
0.858
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
249 |
0.851
|
Human |
|
|
positive regulation of map kinase activity
|
GO:0043406 |
84 |
0.846
|
Human |
|
|
bone resorption
|
GO:0045453 |
38 |
0.840
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
120 |
0.833
|
Human |
|
|
mapk cascade
|
GO:0000165 |
281 |
0.831
|
Human |
|
|
leukocyte differentiation
|
GO:0002521 |
342 |
0.829
|
Human Mouse |
|
|
protein catabolic process
|
GO:0030163 |
221 |
0.817
|
|
|
|
regulation of cytokine secretion
|
GO:0050707 |
61 |
0.813
|
Mouse |
|
|
regulation of cell activation
|
GO:0050865 |
289 |
0.811
|
Mouse |
|
|
carbohydrate metabolic process
|
GO:0005975 |
230 |
0.810
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
155 |
0.799
|
Human |
|
|
regulation of transferase activity
|
GO:0051338 |
263 |
0.789
|
Human |
|
|
defense response to other organism
|
GO:0098542 |
197 |
0.788
|
Mouse |
|
|
multicellular organismal homeostasis
|
GO:0048871 |
164 |
0.786
|
|
|
|
regulation of cell migration
|
GO:0030334 |
219 |
0.786
|
Mouse |
|
|
adaptive immune response
|
GO:0002250 |
155 |
0.764
|
Human Mouse |
|
|
gland development
|
GO:0048732 |
330 |
0.756
|
|
|
|
organic anion transport
|
GO:0015711 |
137 |
0.751
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
80 |
0.749
|
Human |
|
|
positive regulation of cytokine production
|
GO:0001819 |
174 |
0.746
|
Mouse |
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
106 |
0.745
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
145 |
0.721
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
85 |
0.715
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
145 |
0.700
|
Mouse |
|
|
regulation of secretion by cell
|
GO:1903530 |
249 |
0.699
|
Mouse |
|
|
cation homeostasis
|
GO:0055080 |
212 |
0.696
|
Mouse |
|
|
transmission of nerve impulse
|
GO:0019226 |
76 |
0.690
|
Mouse |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
303 |
0.676
|
|
|
|
osteoclast differentiation
|
GO:0030316 |
62 |
0.668
|
Human |
|
|
jnk cascade
|
GO:0007254 |
72 |
0.650
|
Human |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
68 |
0.648
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
170 |
0.643
|
Human |
|
|
t cell activation
|
GO:0042110 |
289 |
0.643
|
Mouse |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
144 |
0.620
|
Human |
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
119 |
0.614
|
Human Mouse |
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
47 |
0.612
|
Human |
|
|
neural tube formation
|
GO:0001841 |
108 |
0.610
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
62 |
0.608
|
Human |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
106 |
0.600
|
Human |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
217 |
0.586
|
|
|
|
carboxylic acid transport
|
GO:0046942 |
100 |
0.583
|
|
|
|
respiratory tube development
|
GO:0030323 |
167 |
0.581
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.581
|
|
|
|
t cell proliferation
|
GO:0042098 |
120 |
0.575
|
Mouse |
|
|
regulation of protein localization
|
GO:0032880 |
231 |
0.574
|
Mouse |
|
|
positive regulation of cell death
|
GO:0010942 |
224 |
0.564
|
|
|
|
regulation of protein transport
|
GO:0051223 |
163 |
0.563
|
Mouse |
|
|
cytokine secretion
|
GO:0050663 |
72 |
0.561
|
Mouse |
|
|
regulation of jun kinase activity
|
GO:0043506 |
40 |
0.550
|
Human |
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
48 |
0.543
|
Human |
|
|
macromolecule catabolic process
|
GO:0009057 |
281 |
0.541
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
124 |
0.536
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
81 |
0.534
|
Human |
|
|
calcium ion transport
|
GO:0006816 |
159 |
0.534
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
4 |
0.532
|
|
|
|
regulation of interleukin 10 secretion
|
GO:2001179 |
4 |
0.529
|
Mouse |
|
|
divalent inorganic cation transport
|
GO:0072511 |
178 |
0.527
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
69 |
0.521
|
Human |
|
|
immune response activating signal transduction
|
GO:0002757 |
116 |
0.499
|
Zebrafish Mouse |
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
183 |
0.495
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
111 |
0.495
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
127 |
0.494
|
Mouse |
|
|
organic acid transport
|
GO:0015849 |
101 |
0.494
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
174 |
0.491
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
170 |
0.488
|
Mouse |
|
|
myeloid cell differentiation
|
GO:0030099 |
233 |
0.484
|
Human Mouse |
|
|
positive regulation of transferase activity
|
GO:0051347 |
167 |
0.483
|
Human |
|
|
regulation of cellular response to stress
|
GO:0080135 |
159 |
0.475
|
Human |
|
|
regulation of myeloid leukocyte differentiation
|
GO:0002761 |
58 |
0.474
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
128 |
0.469
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
241 |
0.465
|
|
|
|
negative regulation of serotonin secretion
|
GO:0014063 |
2 |
0.462
|
|
|
|
muscle cell development
|
GO:0055001 |
133 |
0.462
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
209 |
0.454
|
Mouse |
|
|
regulation of defense response
|
GO:0031347 |
233 |
0.452
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
64 |
0.446
|
|
|
|
regulation of leukocyte mediated immunity
|
GO:0002703 |
104 |
0.445
|
Mouse |
|
|
regulation of protein kinase activity
|
GO:0045859 |
232 |
0.444
|
Human |
|
|
cytokine production
|
GO:0001816 |
319 |
0.439
|
Mouse |
|
|
myeloid dendritic cell differentiation
|
GO:0043011 |
16 |
0.439
|
Mouse |
|
|
regulation of cell motility
|
GO:2000145 |
236 |
0.439
|
Mouse |
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
83 |
0.438
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
174 |
0.436
|
Mouse |
|
|
positive regulation of cell migration
|
GO:0030335 |
109 |
0.435
|
Mouse |
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
141 |
0.433
|
|
|
|
immunoglobulin secretion
|
GO:0048305 |
17 |
0.431
|
Mouse |
|
|
cation transport
|
GO:0006812 |
399 |
0.430
|
|
|
|
ensheathment of neurons
|
GO:0007272 |
76 |
0.429
|
Mouse |
|
|
mammary gland epithelium development
|
GO:0061180 |
65 |
0.426
|
|
|
|
positive regulation of fever generation by positive regulation of prostaglandin secretion
|
GO:0071812 |
2 |
0.423
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
296 |
0.419
|
Mouse |
|
|
production of molecular mediator of immune response
|
GO:0002440 |
103 |
0.417
|
Mouse |
|
|
gliogenesis
|
GO:0042063 |
141 |
0.412
|
Mouse |
|
|
epithelial tube formation
|
GO:0072175 |
130 |
0.412
|
|
|
|
alpha beta t cell activation
|
GO:0046631 |
91 |
0.411
|
Mouse |
|
|
positive regulation of secretion
|
GO:0051047 |
130 |
0.405
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
242 |
0.403
|
Human Mouse |
|
|
innate immune response
|
GO:0045087 |
157 |
0.402
|
Zebrafish |
|
|
regulation of ion transport
|
GO:0043269 |
215 |
0.397
|
|
|
|
lipid transport
|
GO:0006869 |
98 |
0.395
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
71 |
0.391
|
Human |
|
|
morphogenesis of a branching structure
|
GO:0001763 |
203 |
0.390
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
189 |
0.389
|
Mouse |
|
|
nucleotide catabolic process
|
GO:0009166 |
217 |
0.389
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
82 |
0.387
|
Mouse |
|
|
bone remodeling
|
GO:0046849 |
53 |
0.383
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
218 |
0.380
|
|
|
|
developmental maturation
|
GO:0021700 |
193 |
0.379
|
|
|
|
fatty acid transport
|
GO:0015908 |
28 |
0.379
|
|
|
|
interleukin 6 production
|
GO:0032635 |
58 |
0.378
|
|
|
|
anion transport
|
GO:0006820 |
177 |
0.376
|
|
|
|
action potential
|
GO:0001508 |
78 |
0.372
|
Mouse |
|
|
respiratory system development
|
GO:0060541 |
190 |
0.369
|
|
|
|
lung development
|
GO:0030324 |
164 |
0.364
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
291 |
0.362
|
|
|
|
defense response to virus
|
GO:0051607 |
68 |
0.360
|
Mouse |
|
|
cellular response to lipid
|
GO:0071396 |
145 |
0.359
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
77 |
0.357
|
|
|
|
interleukin 5 secretion
|
GO:0072603 |
2 |
0.357
|
Mouse |
|
|
positive regulation of secretion by cell
|
GO:1903532 |
114 |
0.356
|
Mouse |
|
|
rhythmic process
|
GO:0048511 |
174 |
0.356
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
84 |
0.354
|
Mouse |
|
|
muscle cell proliferation
|
GO:0033002 |
52 |
0.350
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
143 |
0.347
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
211 |
0.345
|
|
|
|
dendritic cell differentiation
|
GO:0097028 |
26 |
0.342
|
Mouse |
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
140 |
0.341
|
Mouse |
|
|
molting cycle
|
GO:0042303 |
90 |
0.341
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
77 |
0.340
|
Mouse |
|
|
activation of nf kappab inducing kinase activity
|
GO:0007250 |
4 |
0.337
|
|
|
|
neural tube development
|
GO:0021915 |
160 |
0.336
|
|
|
|
regulation of interleukin 12 production
|
GO:0032655 |
30 |
0.336
|
Mouse |
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
121 |
0.334
|
Mouse |
|
|
ras protein signal transduction
|
GO:0007265 |
77 |
0.331
|
|
|
|
forebrain development
|
GO:0030900 |
302 |
0.330
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
181 |
0.325
|
Mouse |
|
|
positive regulation of jnk cascade
|
GO:0046330 |
46 |
0.324
|
Human |
|
|
regulation of inflammatory response
|
GO:0050727 |
147 |
0.321
|
|
|
|
acid secretion
|
GO:0046717 |
33 |
0.321
|
|
|
|
heat generation
|
GO:0031649 |
13 |
0.312
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
79 |
0.312
|
|
|
|
negative regulation of secretion by cell
|
GO:1903531 |
54 |
0.311
|
Mouse |
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
114 |
0.309
|
|
|
|
body fluid secretion
|
GO:0007589 |
53 |
0.308
|
|
|
|
interleukin 10 secretion
|
GO:0072608 |
4 |
0.308
|
Mouse |
|
|
glucose import
|
GO:0046323 |
32 |
0.307
|
|
|
|
epidermis development
|
GO:0008544 |
187 |
0.307
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
306 |
0.304
|
Mouse |
|
|
neuronal action potential
|
GO:0019228 |
54 |
0.304
|
Mouse |
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
84 |
0.298
|
Mouse |
|
|
regulation of membrane potential
|
GO:0042391 |
192 |
0.298
|
Mouse |
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
352 |
0.298
|
|
|
|
positive regulation of protein modification process
|
GO:0031401 |
299 |
0.294
|
Human Mouse |
|
|
skin development
|
GO:0043588 |
220 |
0.291
|
|
|
|
regulation of interleukin 13 secretion
|
GO:2000665 |
2 |
0.287
|
Mouse |
|
|
positive regulation of lymphocyte proliferation
|
GO:0050671 |
70 |
0.287
|
Mouse |
|
|
purine nucleotide metabolic process
|
GO:0006163 |
302 |
0.286
|
|
|
|
toll like receptor signaling pathway
|
GO:0002224 |
38 |
0.285
|
Zebrafish |
|
|
monocarboxylic acid transport
|
GO:0015718 |
44 |
0.285
|
|
|
|
nucleoside metabolic process
|
GO:0009116 |
246 |
0.285
|
|
|
|
myeloid leukocyte activation
|
GO:0002274 |
83 |
0.284
|
Mouse |
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
73 |
0.282
|
Mouse |
|
|
cell adhesion
|
GO:0007155 |
329 |
0.278
|
|
|
|
glial cell differentiation
|
GO:0010001 |
131 |
0.276
|
Mouse |
|
|
leukocyte proliferation
|
GO:0070661 |
172 |
0.274
|
Mouse |
|
|
membrane organization
|
GO:0061024 |
245 |
0.273
|
|
|
|
regulation of fatty acid transport
|
GO:2000191 |
10 |
0.269
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
165 |
0.269
|
Mouse |
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
205 |
0.268
|
|
|
|
cellular response to biotic stimulus
|
GO:0071216 |
92 |
0.268
|
|
|
|
extracellular matrix organization
|
GO:0030198 |
147 |
0.267
|
Mouse |
|
|
regulation of lymphocyte activation
|
GO:0051249 |
240 |
0.265
|
Mouse |
|
|
second messenger mediated signaling
|
GO:0019932 |
73 |
0.262
|
|
|
|
glycosyl compound metabolic process
|
GO:1901657 |
246 |
0.261
|
|
|
|
axon ensheathment
|
GO:0008366 |
76 |
0.259
|
Mouse |
|
|
myeloid leukocyte migration
|
GO:0097529 |
57 |
0.258
|
|
|
|
negative regulation of interleukin 5 production
|
GO:0032714 |
4 |
0.255
|
Mouse |
|
|
lipid biosynthetic process
|
GO:0008610 |
179 |
0.253
|
|
|
|
regulation of system process
|
GO:0044057 |
200 |
0.253
|
|
|
|
positive regulation of interleukin 6 production
|
GO:0032755 |
37 |
0.253
|
|
|
|
inflammatory response
|
GO:0006954 |
244 |
0.252
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
280 |
0.252
|
|
|
|
extracellular structure organization
|
GO:0043062 |
148 |
0.251
|
Mouse |
|
|
skeletal system development
|
GO:0001501 |
356 |
0.250
|
|
|
|
leukocyte migration
|
GO:0050900 |
124 |
0.247
|
Mouse |
|
|
positive regulation of immune effector process
|
GO:0002699 |
107 |
0.247
|
Mouse |
|
|
leukocyte activation involved in immune response
|
GO:0002366 |
126 |
0.247
|
Mouse |
|
|
embryonic epithelial tube formation
|
GO:0001838 |
130 |
0.247
|
|
|
|
positive regulation of osteoclast differentiation
|
GO:0045672 |
15 |
0.245
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
159 |
0.245
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
41 |
0.245
|
Mouse |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
159 |
0.242
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
248 |
0.242
|
Human |
|
|
primary neural tube formation
|
GO:0014020 |
95 |
0.241
|
|
|
|
ossification
|
GO:0001503 |
216 |
0.240
|
|
|
|
regulation of osteoclast differentiation
|
GO:0045670 |
36 |
0.234
|
|
|
|
positive regulation of protein secretion
|
GO:0050714 |
52 |
0.233
|
Mouse |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
5 |
0.233
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
144 |
0.230
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
193 |
0.230
|
|
|
|
activation of mapk activity
|
GO:0000187 |
59 |
0.230
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
199 |
0.230
|
|
|
|
neural tube closure
|
GO:0001843 |
90 |
0.230
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
20 |
0.229
|
|
|
|
necrotic cell death
|
GO:0070265 |
30 |
0.227
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
26 |
0.224
|
Mouse |
|
|
stem cell proliferation
|
GO:0072089 |
117 |
0.221
|
|
|
|
regulation of hormone secretion
|
GO:0046883 |
88 |
0.221
|
|
|
|
axon guidance
|
GO:0007411 |
141 |
0.219
|
|
|
|
cell fate commitment
|
GO:0045165 |
210 |
0.218
|
|
|
|
cellular homeostasis
|
GO:0019725 |
240 |
0.218
|
Mouse |
|
|
b cell activation
|
GO:0042113 |
161 |
0.217
|
Mouse |
|
|
positive regulation of protein transport
|
GO:0051222 |
93 |
0.214
|
Mouse |
|
|
interleukin 13 secretion
|
GO:0072611 |
2 |
0.214
|
Mouse |
|
|
aromatic compound catabolic process
|
GO:0019439 |
286 |
0.214
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
84 |
0.213
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
68 |
0.213
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
291 |
0.211
|
|
|
|
interleukin 12 production
|
GO:0032615 |
32 |
0.208
|
Mouse |
|
|
positive regulation of cell activation
|
GO:0050867 |
158 |
0.207
|
Mouse |
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
72 |
0.205
|
Mouse |
|
|
oligodendrocyte differentiation
|
GO:0048709 |
53 |
0.205
|
Mouse |
|
|
defense response to bacterium
|
GO:0042742 |
119 |
0.204
|
Mouse |
|
|
gtp catabolic process
|
GO:0006184 |
143 |
0.203
|
|
|
|
chemotaxis
|
GO:0006935 |
247 |
0.203
|
|
|
|
positive regulation of fatty acid transport
|
GO:2000193 |
8 |
0.202
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
237 |
0.201
|
|
|
|
corticotropin releasing hormone secretion
|
GO:0043396 |
2 |
0.200
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
126 |
0.200
|
Mouse |
|
|
ion transmembrane transport
|
GO:0034220 |
361 |
0.200
|
|
|
|
lymphocyte differentiation
|
GO:0030098 |
242 |
0.198
|
|
|
|
t cell differentiation
|
GO:0030217 |
174 |
0.197
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
189 |
0.197
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
192 |
0.196
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
213 |
0.196
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
125 |
0.196
|
Zebrafish Mouse |
|
|
regulation of neuron differentiation
|
GO:0045664 |
281 |
0.195
|
|
|
|
adenylate cyclase modulating g protein coupled receptor signaling pathway
|
GO:0007188 |
54 |
0.195
|
|
|
|
regulation of striated muscle cell differentiation
|
GO:0051153 |
81 |
0.195
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
211 |
0.194
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
261 |
0.193
|
|
|
|
intracellular protein transport
|
GO:0006886 |
204 |
0.193
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
65 |
0.193
|
|
|
|
wound healing
|
GO:0042060 |
157 |
0.192
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
189 |
0.192
|
|
|
|
organic hydroxy compound transport
|
GO:0015850 |
93 |
0.192
|
|
|
|
cytosolic calcium ion homeostasis
|
GO:0051480 |
70 |
0.191
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
258 |
0.191
|
|
|
|
lymphocyte activation involved in immune response
|
GO:0002285 |
93 |
0.186
|
Mouse |
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
43 |
0.186
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
61 |
0.186
|
Mouse |
|
|
antimicrobial peptide production
|
GO:0002775 |
2 |
0.181
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
226 |
0.181
|
|
|
|
regulation of blood circulation
|
GO:1903522 |
93 |
0.181
|
|
|
|
necroptotic process
|
GO:0070266 |
21 |
0.179
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
230 |
0.177
|
|
|
|
odontogenesis
|
GO:0042476 |
78 |
0.176
|
Mouse |
|
|
digestive tract development
|
GO:0048565 |
190 |
0.176
|
|
|
|
regulation of myoblast differentiation
|
GO:0045661 |
29 |
0.175
|
|
|
|
dna metabolic process
|
GO:0006259 |
303 |
0.174
|
Mouse |
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
119 |
0.172
|
|
|
|
regulation of organ morphogenesis
|
GO:2000027 |
144 |
0.171
|
Mouse |
|
|
cell substrate adhesion
|
GO:0031589 |
130 |
0.171
|
|
|
|
hormone secretion
|
GO:0046879 |
128 |
0.170
|
|
|
|
positive regulation of cytokine production involved in immune response
|
GO:0002720 |
19 |
0.167
|
Mouse |
|
|
digestive system development
|
GO:0055123 |
200 |
0.167
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
162 |
0.167
|
|
|
|
lipid localization
|
GO:0010876 |
126 |
0.166
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
24 |
0.166
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
145 |
0.165
|
|
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
80 |
0.163
|
Mouse |
|
|
negative regulation of interleukin 5 secretion
|
GO:2000663 |
1 |
0.163
|
Mouse |
|
|
regulation of gliogenesis
|
GO:0014013 |
50 |
0.160
|
Mouse |
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
338 |
0.160
|
|
|
|
regulation of lipid transport
|
GO:0032368 |
36 |
0.160
|
|
|
|
odontogenesis of dentin containing tooth
|
GO:0042475 |
66 |
0.160
|
Mouse |
|
|
interleukin 1 mediated signaling pathway
|
GO:0070498 |
4 |
0.159
|
|
|
|
alpha beta t cell differentiation
|
GO:0046632 |
69 |
0.158
|
|
|
|
heart contraction
|
GO:0060047 |
93 |
0.158
|
|
|
|
cellular response to nitric oxide
|
GO:0071732 |
4 |
0.157
|
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
264 |
0.157
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
198 |
0.156
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
65 |
0.155
|
Mouse |
|
|
skeletal muscle fiber development
|
GO:0048741 |
58 |
0.154
|
|
|
|
forebrain cell migration
|
GO:0021885 |
58 |
0.154
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
323 |
0.154
|
|
|
|
cellular response to amino acid stimulus
|
GO:0071230 |
29 |
0.153
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
70 |
0.153
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
59 |
0.153
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
172 |
0.152
|
|
|
|
humoral immune response
|
GO:0006959 |
57 |
0.152
|
Mouse |
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
68 |
0.152
|
|
|
|
axonogenesis
|
GO:0007409 |
274 |
0.152
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
54 |
0.152
|
Mouse |
|
|
positive regulation of myoblast differentiation
|
GO:0045663 |
8 |
0.151
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
159 |
0.151
|
|
|
|
myelination
|
GO:0042552 |
74 |
0.151
|
Mouse |
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
295 |
0.151
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
182 |
0.151
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
3 |
0.150
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
164 |
0.149
|
Mouse |
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
30 |
0.149
|
Human |
|
|
keratinocyte migration
|
GO:0051546 |
3 |
0.148
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
155 |
0.148
|
|
|
|
myotube differentiation
|
GO:0014902 |
105 |
0.147
|
|
|
|
regulation of ion transmembrane transport
|
GO:0034765 |
119 |
0.145
|
|
|
|
g protein coupled receptor internalization
|
GO:0002031 |
3 |
0.145
|
|
|
|
nucleotide metabolic process
|
GO:0009117 |
332 |
0.143
|
|
|
|
digestion
|
GO:0007586 |
40 |
0.143
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
15 |
0.142
|
|
|
|
response to nutrient levels
|
GO:0031667 |
109 |
0.141
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
148 |
0.140
|
|
|
|
central nervous system neuron differentiation
|
GO:0021953 |
162 |
0.140
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
115 |
0.138
|
|
|
|
positive regulation of peptide hormone secretion
|
GO:0090277 |
31 |
0.138
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
234 |
0.138
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
77 |
0.138
|
Human |
|
|
tube formation
|
GO:0035148 |
140 |
0.137
|
|
|
|
mammary gland alveolus development
|
GO:0060749 |
22 |
0.137
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
69 |
0.137
|
|
|
|
positive regulation of macrophage derived foam cell differentiation
|
GO:0010744 |
4 |
0.136
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
276 |
0.136
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
184 |
0.135
|
|
|
|
telencephalon cell migration
|
GO:0022029 |
55 |
0.134
|
|
|
|
hair follicle development
|
GO:0001942 |
85 |
0.134
|
|
|
|
protein kinase c activating g protein coupled receptor signaling pathway
|
GO:0007205 |
4 |
0.134
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
106 |
0.133
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
280 |
0.133
|
|
|
|
hair cycle
|
GO:0042633 |
90 |
0.133
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
78 |
0.133
|
|
|
|
regulation of ion homeostasis
|
GO:2000021 |
64 |
0.132
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
234 |
0.131
|
|
|
|
hair cycle phase
|
GO:0044851 |
16 |
0.131
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
203 |
0.131
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
116 |
0.130
|
Mouse |
|
|
tube closure
|
GO:0060606 |
91 |
0.130
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
188 |
0.130
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
285 |
0.129
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
65 |
0.128
|
|
|
|
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002822 |
87 |
0.128
|
Mouse |
|
|
ribonucleoside catabolic process
|
GO:0042454 |
206 |
0.128
|
|
|
|
synaptic transmission
|
GO:0007268 |
329 |
0.128
|
|
|
|
myotube cell development
|
GO:0014904 |
60 |
0.127
|
|
|
|
cell chemotaxis
|
GO:0060326 |
81 |
0.127
|
|
|
|
regulation of skeletal muscle fiber development
|
GO:0048742 |
36 |
0.127
|
|
|
|
angiogenesis
|
GO:0001525 |
201 |
0.126
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
97 |
0.126
|
|
|
|
peptide transport
|
GO:0015833 |
133 |
0.126
|
|
|
|
regulation of corticotropin releasing hormone secretion
|
GO:0043397 |
2 |
0.126
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
91 |
0.126
|
Mouse |
|
|
regulation of t cell mediated immunity
|
GO:0002709 |
34 |
0.125
|
|
|
|
appendage development
|
GO:0048736 |
166 |
0.125
|
|
|
|
calcium ion transport into cytosol
|
GO:0060402 |
48 |
0.125
|
|
|
|
protein processing
|
GO:0016485 |
163 |
0.124
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
243 |
0.124
|
|
|
|
regulation of peptide hormone secretion
|
GO:0090276 |
75 |
0.124
|
|
|
|
regulation of serotonin secretion
|
GO:0014062 |
3 |
0.123
|
|
|
|
mammary gland lobule development
|
GO:0061377 |
22 |
0.123
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
151 |
0.122
|
Mouse |
|
|
oocyte differentiation
|
GO:0009994 |
35 |
0.122
|
|
|
|
regionalization
|
GO:0003002 |
337 |
0.120
|
|
|
|
b cell differentiation
|
GO:0030183 |
78 |
0.120
|
|
|
|
circadian rhythm
|
GO:0007623 |
114 |
0.117
|
|
|
|
positive regulation of myeloid leukocyte differentiation
|
GO:0002763 |
26 |
0.117
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
143 |
0.117
|
Mouse |
|
|
cytokine metabolic process
|
GO:0042107 |
71 |
0.116
|
|
|
|
regulation of transmembrane transport
|
GO:0034762 |
128 |
0.116
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
220 |
0.116
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
32 |
0.116
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
311 |
0.115
|
|
|
|
glucan metabolic process
|
GO:0044042 |
32 |
0.115
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
40 |
0.114
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
127 |
0.114
|
Mouse |
|
|
kidney development
|
GO:0001822 |
213 |
0.113
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
232 |
0.113
|
|
|
|
antimicrobial peptide biosynthetic process
|
GO:0002777 |
2 |
0.113
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
57 |
0.112
|
Mouse |
|
|
t helper 1 type immune response
|
GO:0042088 |
25 |
0.111
|
|
|
|
amine metabolic process
|
GO:0009308 |
45 |
0.111
|
|
|
|
negative regulation of interleukin 13 production
|
GO:0032696 |
2 |
0.111
|
Mouse |
|
|
urogenital system development
|
GO:0001655 |
261 |
0.111
|
|
|
|
phospholipase c activating g protein coupled receptor signaling pathway
|
GO:0007200 |
26 |
0.110
|
|
|
|
positive regulation of lymphocyte mediated immunity
|
GO:0002708 |
62 |
0.110
|
Mouse |
|
|
pallium development
|
GO:0021543 |
120 |
0.110
|
|
|
|
positive regulation of nucleotide biosynthetic process
|
GO:0030810 |
26 |
0.108
|
|
|
|
regulation of antigen receptor mediated signaling pathway
|
GO:0050854 |
29 |
0.108
|
|
|
|
endocytosis
|
GO:0006897 |
168 |
0.108
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
119 |
0.108
|
Mouse |
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
40 |
0.107
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
85 |
0.107
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.107
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
44 |
0.106
|
|
|
|
striated muscle cell development
|
GO:0055002 |
125 |
0.106
|
|
|
|
sensory perception
|
GO:0007600 |
245 |
0.106
|
|
|
|
mammary gland morphogenesis
|
GO:0060443 |
54 |
0.106
|
|
|
|
programmed necrotic cell death
|
GO:0097300 |
28 |
0.106
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.106
|
|
|
|
positive regulation of hormone secretion
|
GO:0046887 |
38 |
0.105
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
114 |
0.105
|
|
|
|
positive regulation of antimicrobial peptide biosynthetic process
|
GO:0002807 |
1 |
0.105
|
|
|
|
regulation of oligodendrocyte differentiation
|
GO:0048713 |
23 |
0.104
|
Mouse |
|
|
germ cell development
|
GO:0007281 |
185 |
0.104
|
|
|
|
regulation of muscle system process
|
GO:0090257 |
80 |
0.104
|
|
|
|
peptide secretion
|
GO:0002790 |
114 |
0.104
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
132 |
0.103
|
Mouse |
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
290 |
0.103
|
|
|
|
positive regulation of cyclic nucleotide metabolic process
|
GO:0030801 |
24 |
0.103
|
|
|
|
icosanoid secretion
|
GO:0032309 |
12 |
0.103
|
|
|
|
t cell mediated immunity
|
GO:0002456 |
50 |
0.103
|
|
|
|
positive regulation of t cell activation
|
GO:0050870 |
101 |
0.103
|
|
|
|
regulation of carbohydrate metabolic process
|
GO:0006109 |
75 |
0.102
|
|
|
|
protein localization to organelle
|
GO:0033365 |
185 |
0.102
|
|
|
|
cellular response to inorganic substance
|
GO:0071241 |
37 |
0.101
|
|
|
|
peptide hormone secretion
|
GO:0030072 |
109 |
0.101
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
145 |
0.101
|
Mouse |
|
|
sodium ion transport
|
GO:0006814 |
73 |
0.100
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
45 |
0.100
|
Mouse |
|
|
nucleoside catabolic process
|
GO:0009164 |
206 |
0.099
|
|
|
|
positive regulation of antimicrobial peptide production
|
GO:0002225 |
1 |
0.099
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
206 |
0.098
|
|
|
|
telencephalon development
|
GO:0021537 |
186 |
0.098
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
164 |
0.098
|
|
|
|
amide transport
|
GO:0042886 |
138 |
0.098
|
|
|
|
regulation of immunoglobulin secretion
|
GO:0051023 |
12 |
0.097
|
Mouse |
|
|
regulation of calcium ion transport
|
GO:0051924 |
69 |
0.097
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
246 |
0.097
|
|
|
|
glial cell development
|
GO:0021782 |
54 |
0.096
|
|
|
|
epithelial cell development
|
GO:0002064 |
159 |
0.096
|
|
|
|
positive regulation of cellular carbohydrate metabolic process
|
GO:0010676 |
29 |
0.096
|
|
|
|
transmembrane transport
|
GO:0055085 |
412 |
0.096
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
112 |
0.096
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
128 |
0.095
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
122 |
0.094
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
45 |
0.094
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
114 |
0.094
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
90 |
0.094
|
Mouse |
|
|
oxidation reduction process
|
GO:0055114 |
342 |
0.092
|
|
|
|
alcohol biosynthetic process
|
GO:0046165 |
43 |
0.092
|
|
|
|
tolerance induction
|
GO:0002507 |
14 |
0.092
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
106 |
0.091
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
83 |
0.091
|
|
|
|
cell division
|
GO:0051301 |
120 |
0.091
|
|
|
|
immunoglobulin production
|
GO:0002377 |
73 |
0.091
|
Mouse |
|
|
positive regulation of icosanoid secretion
|
GO:0032305 |
7 |
0.091
|
|
|
|
epithelial cell morphogenesis
|
GO:0003382 |
41 |
0.091
|
|
|
|
positive regulation of syncytium formation by plasma membrane fusion
|
GO:0060143 |
17 |
0.091
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
91 |
0.090
|
Zebrafish |
|
|
glycogen metabolic process
|
GO:0005977 |
32 |
0.090
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
39 |
0.090
|
|
|
|
multi multicellular organism process
|
GO:0044706 |
109 |
0.090
|
|
|
|
positive regulation of inflammatory response
|
GO:0050729 |
47 |
0.088
|
|
|
|
negative regulation of exocytosis
|
GO:0045920 |
12 |
0.088
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
208 |
0.088
|
|
|
|
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002824 |
61 |
0.088
|
Mouse |
|
|
regulation of cellular carbohydrate metabolic process
|
GO:0010675 |
75 |
0.088
|
|
|
|
vitamin d biosynthetic process
|
GO:0042368 |
3 |
0.088
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
206 |
0.088
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
208 |
0.087
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
38 |
0.087
|
|
|
|
positive regulation of antimicrobial humoral response
|
GO:0002760 |
2 |
0.087
|
|
|
|
branching involved in mammary gland duct morphogenesis
|
GO:0060444 |
27 |
0.087
|
|
|
|
carbohydrate transport
|
GO:0008643 |
62 |
0.087
|
|
|
|
forebrain neuron differentiation
|
GO:0021879 |
52 |
0.087
|
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
246 |
0.086
|
|
|
|
placenta development
|
GO:0001890 |
140 |
0.086
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
82 |
0.085
|
|
|
|
cell activation involved in immune response
|
GO:0002263 |
126 |
0.085
|
Mouse |
|
|
regulation of intracellular transport
|
GO:0032386 |
159 |
0.085
|
|
|
|
regulation of tissue remodeling
|
GO:0034103 |
38 |
0.085
|
|
|
|
glucose homeostasis
|
GO:0042593 |
128 |
0.084
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
112 |
0.084
|
|
|
|
positive regulation of translational initiation
|
GO:0045948 |
4 |
0.083
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
215 |
0.083
|
Mouse |
|
|
cellular response to acid chemical
|
GO:0071229 |
68 |
0.083
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
64 |
0.082
|
Mouse |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
220 |
0.082
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
122 |
0.081
|
|
|
|
positive regulation of myotube differentiation
|
GO:0010831 |
24 |
0.081
|
|
|
|
blastocyst development
|
GO:0001824 |
80 |
0.081
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
242 |
0.081
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
66 |
0.081
|
|
|
|
protein oligomerization
|
GO:0051259 |
67 |
0.080
|
|
|
|
response to oxidative stress
|
GO:0006979 |
123 |
0.080
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
203 |
0.079
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
169 |
0.079
|
|
|
|
maternal process involved in female pregnancy
|
GO:0060135 |
32 |
0.079
|
|
|
|
calcium mediated signaling
|
GO:0019722 |
46 |
0.079
|
|
