IMP

Process View

Mus musculus

16 genes annotated in mouse

myeloid dendritic cell differentiation

The process in which a monocyte acquires the specialized features of a dendritic cell, an immunocompetent cell of the lymphoid and hemopoietic systems and skin.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "myeloid dendritic cell differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "myeloid dendritic cell differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	1.000	Mouse
Igh	immunoglobulin heavy chain complex	0.998
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.994	Mouse
Notch1	Notch gene homolog 1 (Drosophila)	0.990	Mouse
Psen1	presenilin 1	0.982
Ctnnb1	catenin (cadherin associated protein), beta 1	0.952
Cd19	CD19 antigen	0.928
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.902
Cd40	CD40 antigen	0.902	Mouse
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.875
Ifng	interferon gamma	0.868
Socs1	suppressor of cytokine signaling 1	0.818
Notch2	Notch gene homolog 2 (Drosophila)	0.816
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.809
Irf4	interferon regulatory factor 4	0.804
Irf5	interferon regulatory factor 5	0.803	Mouse
Csf1	colony stimulating factor 1 (macrophage)	0.797
Tnf	tumor necrosis factor	0.782
Bcl3	B-cell leukemia/lymphoma 3	0.746
Pten	phosphatase and tensin homolog	0.617
Rarg	retinoic acid receptor, gamma	0.611
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.575
Ikzf1	IKAROS family zinc finger 1	0.539
Stat2	signal transducer and activator of transcription 2	0.519
Sykb	spleen tyrosine kinase	0.495
Traf6	TNF receptor-associated factor 6	0.486
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.483
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.458
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.439	Mouse
Cd180	CD180 antigen	0.418
Bcl6	B-cell leukemia/lymphoma 6	0.406
Foxc1	forkhead box C1	0.385
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.378
Fgfr2	fibroblast growth factor receptor 2	0.345
Ccl4	chemokine (C-C motif) ligand 4	0.339
Traf2	TNF receptor-associated factor 2	0.334	Mouse
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.315
Sfpi1	SFFV proviral integration 1	0.310
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.307
Psen2	presenilin 2	0.293	Mouse
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.284	Mouse
Pou2f2	POU domain, class 2, transcription factor 2	0.276
Mx2	myxovirus (influenza virus) resistance 2	0.271
Ptf1a	pancreas specific transcription factor, 1a	0.262
Dll1	delta-like 1 (Drosophila)	0.250
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.228
Tcirg1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3	0.216
Lta	lymphotoxin A	0.214
Fas	Fas (TNF receptor superfamily member 6)	0.203
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.203
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.193
Il10ra	interleukin 10 receptor, alpha	0.173
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.172
Batf	basic leucine zipper transcription factor, ATF-like	0.160
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.157
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.156
Il4ra	interleukin 4 receptor, alpha	0.156
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.152
Jag1	jagged 1	0.148
Runx1	runt related transcription factor 1	0.140
Vegfa	vascular endothelial growth factor A	0.139
Foxf1a	forkhead box F1a	0.136
Prkcd	protein kinase C, delta	0.132
Cd22	CD22 antigen	0.131
Stat3	signal transducer and activator of transcription 3	0.131
Birc3	baculoviral IAP repeat-containing 3	0.130
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.121
Rag1	recombination activating gene 1	0.115
Apc	adenomatosis polyposis coli	0.113
Nlrp3	NLR family, pyrin domain containing 3	0.107
Nos2	nitric oxide synthase 2, inducible	0.102
Esr1	estrogen receptor 1 (alpha)	0.102
Unc93b1	unc-93 homolog B1 (C. elegans)	0.092
Irf1	interferon regulatory factor 1	0.091	Mouse
Pdcd1	programmed cell death 1	0.088
Ciita	class II transactivator	0.084
S1pr2	sphingosine-1-phosphate receptor 2	0.083
Smad4	MAD homolog 4 (Drosophila)	0.082
Irf7	interferon regulatory factor 7	0.081	Mouse
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.080
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.077
Irf8	interferon regulatory factor 8	0.077	Mouse
Ltb	lymphotoxin B	0.076
Ccr7	chemokine (C-C motif) receptor 7	0.074
Smad3	MAD homolog 3 (Drosophila)	0.073
Ptpn6	protein tyrosine phosphatase, non-receptor type 6	0.072
Gpr132	G protein-coupled receptor 132	0.069
Tap2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)	0.069
Fbn1	fibrillin 1	0.068
Myd88	myeloid differentiation primary response gene 88	0.068
Kit	kit oncogene	0.068
Zeb1	zinc finger E-box binding homeobox 1	0.068
Mavs	mitochondrial antiviral signaling protein	0.065
Uba7	ubiquitin-like modifier activating enzyme 7	0.064
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.063
Rel	reticuloendotheliosis oncogene	0.062	Mouse
Jak3	Janus kinase 3	0.061
Il2rb	interleukin 2 receptor, beta chain	0.060
Inhba	inhibin beta-A	0.060
Tor3a	torsin family 3, member A	0.059
Ncf1	neutrophil cytosolic factor 1	0.059
Tapbp	TAP binding protein	0.059
Nfkbie	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.053
Itk	IL2-inducible T-cell kinase	0.053
Mx1	myxovirus (influenza virus) resistance 1	0.053
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.050	Mouse
Ptgir	prostaglandin I receptor (IP)	0.048
Ikbkb	inhibitor of kappaB kinase beta	0.048
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	0.047
Prdm1	PR domain containing 1, with ZNF domain	0.046
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.045
Il27ra	interleukin 27 receptor, alpha	0.045
Usp18	ubiquitin specific peptidase 18	0.045
Itgal	integrin alpha L	0.045
Bcl2	B-cell leukemia/lymphoma 2	0.044
Il12b	interleukin 12b	0.043
Plekho2	pleckstrin homology domain containing, family O member 2	0.043
Cxcr4	chemokine (C-X-C motif) receptor 4	0.042
Adora2a	adenosine A2a receptor	0.041
Fasl	Fas ligand (TNF superfamily, member 6)	0.040
Plcg2	phospholipase C, gamma 2	0.040
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.039
Vdr	vitamin D receptor	0.039
Zbp1	Z-DNA binding protein 1	0.039
Gdf11	growth differentiation factor 11	0.039	Mouse
Ncstn	nicastrin	0.038
Nos3	nitric oxide synthase 3, endothelial cell	0.038
Icos	inducible T-cell co-stimulator	0.038
Nr1h3	nuclear receptor subfamily 1, group H, member 3	0.037
Cxcl9	chemokine (C-X-C motif) ligand 9	0.036
Trp53	transformation related protein 53	0.035
Ptgs2	prostaglandin-endoperoxide synthase 2	0.033
Slamf8	SLAM family member 8	0.032
Cd4	CD4 antigen	0.032
Dhx58	DEXH (Asp-Glu-X-His) box polypeptide 58	0.032
Btk	Bruton agammaglobulinemia tyrosine kinase	0.032
Tgfb2	transforming growth factor, beta 2	0.032	Mouse
Foxp3	forkhead box P3	0.032
Ptprj	protein tyrosine phosphatase, receptor type, J	0.031
Fes	feline sarcoma oncogene	0.031
Efnb2	ephrin B2	0.031
Il1rn	interleukin 1 receptor antagonist	0.030
Tap1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.030
Tnfrsf13c	tumor necrosis factor receptor superfamily, member 13c	0.030
Cdh5	cadherin 5	0.030
H2-DMb2	histocompatibility 2, class II, locus Mb2	0.030
Stat1	signal transducer and activator of transcription 1	0.030
Tnip1	TNFAIP3 interacting protein 1	0.030
Il17ra	interleukin 17 receptor A	0.029
Jag2	jagged 2	0.029
Dll4	delta-like 4 (Drosophila)	0.029
Spib	Spi-B transcription factor (Spi-1/PU.1 related)	0.029	Mouse
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.028
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.028
Cd40lg	CD40 ligand	0.028
Wnt7a	wingless-related MMTV integration site 7A	0.028
Cd86	CD86 antigen	0.027
Oasl1	2'-5' oligoadenylate synthetase-like 1	0.026
Siglece	sialic acid binding Ig-like lectin E	0.025
Lilrb3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.025
Nup62-il4i1	Nup62-Il4i1 protein	0.025
Hes1	hairy and enhancer of split 1 (Drosophila)	0.024
Ptch1	patched homolog 1	0.024
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.024
Mvp	major vault protein	0.024
Trim21	tripartite motif-containing 21	0.024
Ms4a4c	membrane-spanning 4-domains, subfamily A, member 4C	0.024
Cd8a	CD8 antigen, alpha chain	0.023
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.023
Bmp2	bone morphogenetic protein 2	0.023
Cmklr1	chemokine-like receptor 1	0.023
Dnase1l3	deoxyribonuclease 1-like 3	0.022
Wnt10b	wingless related MMTV integration site 10b	0.022
Pdgfb	platelet derived growth factor, B polypeptide	0.022
Map3k3	mitogen-activated protein kinase kinase kinase 3	0.022
Ikbkg	inhibitor of kappaB kinase gamma	0.022
Traf3ip2	TRAF3 interacting protein 2	0.022
Sdc3	syndecan 3	0.022
Chd7	chromodomain helicase DNA binding protein 7	0.022
Il2ra	interleukin 2 receptor, alpha chain	0.022
Marco	macrophage receptor with collagenous structure	0.022
Vav2	vav 2 oncogene	0.022
Ccl22	chemokine (C-C motif) ligand 22	0.022
Axin1	axin 1	0.022
Hoxd13	homeobox D13	0.022
H2-Oa	histocompatibility 2, O region alpha locus	0.021
Bak1	BCL2-antagonist/killer 1	0.021
Smad7	MAD homolog 7 (Drosophila)	0.021
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.021
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.021
Pou2af1	POU domain, class 2, associating factor 1	0.021
1810019J16Rik	RIKEN cDNA 1810019J16 gene	0.021
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.021
Fcgr1	Fc receptor, IgG, high affinity I	0.020
Ctsw	cathepsin W	0.020
Tgfbr2	transforming growth factor, beta receptor II	0.020
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.020
Ncoa3	nuclear receptor coactivator 3	0.020
Il2rg	interleukin 2 receptor, gamma chain	0.020
Lep	leptin	0.020
Numb	numb gene homolog (Drosophila)	0.019
Cd72	CD72 antigen	0.019
Fcrla	Fc receptor-like A	0.019
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.019
Adam17	a disintegrin and metallopeptidase domain 17	0.019
H2-Eb1	histocompatibility 2, class II antigen E beta	0.019
Prkg1	protein kinase, cGMP-dependent, type I	0.019
Bcl6b	B-cell CLL/lymphoma 6, member B	0.018
Isg15	ISG15 ubiquitin-like modifier	0.018
Egfl7	EGF-like domain 7	0.018
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.018	Mouse
Oas2	2'-5' oligoadenylate synthetase 2	0.017
Apoe	apolipoprotein E	0.017
Des	desmin	0.017
Plin1	perilipin 1	0.017
Parp10	poly (ADP-ribose) polymerase family, member 10	0.017
Ccrl2	chemokine (C-C motif) receptor-like 2	0.017
Oas3	2'-5' oligoadenylate synthetase 3	0.017
Znfx1	zinc finger, NFX1-type containing 1	0.017
Eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2	0.016
Vpreb3	pre-B lymphocyte gene 3	0.016
Gbp1	guanylate binding protein 1	0.016
Hck	hemopoietic cell kinase	0.016
Zbtb7b	zinc finger and BTB domain containing 7B	0.016
Itga4	integrin alpha 4	0.016
Il12rb1	interleukin 12 receptor, beta 1	0.016
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.016
Prkd2	protein kinase D2	0.016
Trp73	transformation related protein 73	0.015
Cd80	CD80 antigen	0.015
Smad1	MAD homolog 1 (Drosophila)	0.015
Trafd1	TRAF type zinc finger domain containing 1	0.015
Gli3	GLI-Kruppel family member GLI3	0.015
Itgav	integrin alpha V	0.015
C5ar1	complement component 5a receptor 1	0.015
Ifnar2	interferon (alpha and beta) receptor 2	0.015
Foxo1	forkhead box O1	0.015
Grin2a	glutamate receptor, ionotropic, NMDA2A (epsilon 1)	0.015
Smad6	MAD homolog 6 (Drosophila)	0.014
Ggt5	gamma-glutamyltransferase 5	0.014
Rhoh	ras homolog gene family, member H	0.014
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.014
Lama5	laminin, alpha 5	0.014
Blk	B lymphoid kinase	0.014
Aph1a	anterior pharynx defective 1a homolog (C. elegans)	0.014
Acvr2b	activin receptor IIB	0.014
Niacr1	niacin receptor 1	0.014
Ubd	ubiquitin D	0.014
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.014
Junb	Jun-B oncogene	0.014
Sh3rf1	SH3 domain containing ring finger 1	0.014
Sharpin	SHANK-associated RH domain interacting protein	0.014
Bdkrb2	bradykinin receptor, beta 2	0.014
Twsg1	twisted gastrulation homolog 1 (Drosophila)	0.013
Tnfrsf18	tumor necrosis factor receptor superfamily, member 18	0.013
Snx20	sorting nexin 20	0.013
Cxcl10	chemokine (C-X-C motif) ligand 10	0.013
Fshr	follicle stimulating hormone receptor	0.013
Pax5	paired box gene 5	0.013
Dusp2	dual specificity phosphatase 2	0.013
Traf1	TNF receptor-associated factor 1	0.013	Mouse
Arid3a	AT rich interactive domain 3A (BRIGHT-like)	0.013
Cidec	cell death-inducing DFFA-like effector c	0.013
Rnf31	ring finger protein 31	0.013
Ikbke	inhibitor of kappaB kinase epsilon	0.013
Tbx3	T-box 3	0.013
Sox9	SRY-box containing gene 9	0.012
Gata3	GATA binding protein 3	0.012
Itgb3	integrin beta 3	0.012
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.012
Rxra	retinoid X receptor alpha	0.012
Fgf15	fibroblast growth factor 15	0.012
Map3k11	mitogen-activated protein kinase kinase kinase 11	0.012
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.012
Adam8	a disintegrin and metallopeptidase domain 8	0.012
Zfp36	zinc finger protein 36	0.012
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.012
Cr2	complement receptor 2	0.012
Runx3	runt related transcription factor 3	0.011
Sh2d2a	SH2 domain protein 2A	0.011
Aire	autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)	0.011
Il10	interleukin 10	0.011
Fbrs	fibrosin	0.011
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.011
Dag1	dystroglycan 1	0.011
Dok1	docking protein 1	0.011
Acvrl1	activin A receptor, type II-like 1	0.011	Mouse
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.011
Daxx	Fas death domain-associated protein	0.011
Npr1	natriuretic peptide receptor 1	0.011
Irgm2	immunity-related GTPase family M member 2	0.011
Snai1	snail homolog 1 (Drosophila)	0.011
Smo	smoothened homolog (Drosophila)	0.010
Pkd1	polycystic kidney disease 1 homolog	0.010
Igtp	interferon gamma induced GTPase	0.010
Aff2	AF4/FMR2 family, member 2	0.010
Rasa4	RAS p21 protein activator 4	0.010
Skil	SKI-like	0.010
Ccl5	chemokine (C-C motif) ligand 5	0.010
Gsk3b	glycogen synthase kinase 3 beta	0.010
Card11	caspase recruitment domain family, member 11	0.010
Cxcr5	chemokine (C-X-C motif) receptor 5	0.010