Mus musculus

197 known processes

Egr2

early growth response 2

(Aliases: Krox20,Krox-20,Zfp-6,Egr-2,Zfp-25,NGF1-B)

Egr2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
ensheathment of neurons GO:0007272 76 0.992
schwann cell differentiation GO:0014037 26 0.987
rhombomere 5 development GO:0021571 4 0.984
neuronal action potential GO:0019228 54 0.973
multicellular organismal signaling GO:0035637 91 0.970
transmission of nerve impulse GO:0019226 76 0.968
axon ensheathment GO:0008366 76 0.959
myelination GO:0042552 74 0.957
regulation of ovulation GO:0060278 3 0.957
Worm
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.953
action potential GO:0001508 78 0.935
rhombomere morphogenesis GO:0021593 2 0.931
gliogenesis GO:0042063 141 0.920
facial nerve structural organization GO:0021612 10 0.882
skeletal system development GO:0001501 356 0.875
negative regulation of ovulation GO:0060280 1 0.873
Worm
rhombomere 3 development GO:0021569 4 0.870
skeletal system morphogenesis GO:0048705 203 0.865
glial cell differentiation GO:0010001 131 0.839
regulation of defense response GO:0031347 233 0.833
peripheral nervous system development GO:0007422 53 0.819
facial nerve development GO:0021561 11 0.812
muscle tissue development GO:0060537 308 0.800
skeletal muscle cell differentiation GO:0035914 66 0.764
facial nerve morphogenesis GO:0021610 11 0.731
chemotaxis GO:0006935 247 0.727
transcription from rna polymerase iii promoter GO:0006383 3 0.723
rhombomere 3 morphogenesis GO:0021658 2 0.708
adrenal cortex formation GO:0035802 2 0.684
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.675
regulation of leukocyte differentiation GO:1902105 159 0.665
Mouse
regulation of cell activation GO:0050865 289 0.656
Mouse
endochondral bone morphogenesis GO:0060350 50 0.651
regulation of cellular catabolic process GO:0031329 242 0.631
regulation of t cell differentiation GO:0045580 83 0.629
Mouse
regulation of membrane potential GO:0042391 192 0.628
metanephric glomerular mesangium development GO:0072223 3 0.625
Mouse
parasympathetic nervous system development GO:0048486 19 0.614
cellular macromolecule catabolic process GO:0044265 206 0.599
ossification GO:0001503 216 0.598
adrenal cortex development GO:0035801 2 0.588
Mouse
cellular response to gamma radiation GO:0071480 4 0.576
Mouse
leukocyte differentiation GO:0002521 342 0.572
Mouse
replacement ossification GO:0036075 26 0.559
central nervous system segmentation GO:0035283 3 0.547
negative regulation of metanephric glomerulus development GO:0072299 1 0.536
Mouse
protein modification by small protein conjugation or removal GO:0070647 207 0.534
bone development GO:0060348 120 0.530
thorax and anterior abdomen determination GO:0007356 1 0.519
Mouse
cellular response to acid chemical GO:0071229 68 0.518
regulation of transferase activity GO:0051338 263 0.518
Worm
nerve development GO:0021675 67 0.512
rhombomere 5 formation GO:0021666 1 0.512
cranial nerve structural organization GO:0021604 13 0.511
lymphocyte differentiation GO:0030098 242 0.479
Mouse
regulation of epidermis development GO:0045682 33 0.475
regulation of kinase activity GO:0043549 249 0.457
Worm
bone morphogenesis GO:0060349 78 0.450
protein modification by small protein conjugation GO:0032446 187 0.445
positive regulation of leukocyte differentiation GO:1902107 86 0.443
Mouse
positive regulation of cell activation GO:0050867 158 0.441
Mouse
mitotic cell cycle process GO:1903047 159 0.437
regulation of map kinase activity GO:0043405 120 0.433
Worm
compound eye development GO:0048749 1 0.431
axon guidance GO:0007411 141 0.424
skeletal muscle organ development GO:0060538 163 0.421
placenta development GO:0001890 140 0.405
hindbrain development GO:0030902 128 0.386
positive regulation of metanephric ureteric bud development GO:2001076 1 0.379
Mouse
gland development GO:0048732 330 0.374
Mouse
t cell differentiation in thymus GO:0033077 77 0.360
Mouse
skin development GO:0043588 220 0.356
oligodendrocyte differentiation GO:0048709 53 0.350
regulation of cell cycle GO:0051726 281 0.344
positive regulation of defense response GO:0031349 124 0.342
nuclear transport GO:0051169 139 0.339
digestive tract development GO:0048565 190 0.337
blood vessel morphogenesis GO:0048514 285 0.325
Mouse
regulation of protein localization GO:0032880 231 0.323
axonogenesis GO:0007409 274 0.321
negative regulation of molecular function GO:0044092 258 0.316
Worm
protein sumoylation GO:0016925 14 0.312
gonad development GO:0008406 141 0.311
Mouse
positive regulation of osteoclast differentiation GO:0045672 15 0.304
regulation of cellular response to stress GO:0080135 159 0.302
regulation of protein serine threonine kinase activity GO:0071900 157 0.294
Worm
t cell differentiation GO:0030217 174 0.294
Mouse
positive regulation of programmed cell death GO:0043068 218 0.277
kidney epithelium development GO:0072073 121 0.273
Mouse
intracellular receptor signaling pathway GO:0030522 74 0.272
cellular response to lipid GO:0071396 145 0.269
striated muscle tissue development GO:0014706 293 0.267
regulation of t cell differentiation in thymus GO:0033081 24 0.263
Mouse
regulation of ossification GO:0030278 112 0.261
positive regulation of t cell activation GO:0050870 101 0.260
Mouse
response to growth factor GO:0070848 198 0.259
negative regulation of cell cycle GO:0045786 123 0.255
negative regulation of protein phosphorylation GO:0001933 126 0.252
Worm
positive regulation of cellular catabolic process GO:0031331 148 0.252
cell growth GO:0016049 130 0.250
anatomical structure arrangement GO:0048532 20 0.249
negative regulation of map kinase activity GO:0043407 34 0.247
Worm
fat cell differentiation GO:0045444 160 0.246
positive regulation of growth GO:0045927 104 0.242
Mouse
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.241
modification dependent macromolecule catabolic process GO:0043632 133 0.238
response to organonitrogen compound GO:0010243 246 0.237
Mouse Rat
negative regulation of phosphate metabolic process GO:0045936 184 0.233
Worm
positive regulation of cell death GO:0010942 224 0.230
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 40 0.228
mitotic cell cycle GO:0000278 195 0.227
cellular response to radiation GO:0071478 28 0.227
Mouse
regulation of cyclin dependent protein serine threonine kinase activity involved in g2 m transition of mitotic cell cycle GO:0031660 1 0.226
regulation of myeloid leukocyte differentiation GO:0002761 58 0.223
lateral line system development GO:0048925 1 0.223
Zebrafish
telencephalon development GO:0021537 186 0.222
gamma delta t cell differentiation GO:0042492 11 0.222
Mouse
lateral line nerve development GO:0048892 1 0.221
Zebrafish
response to molecule of bacterial origin GO:0002237 143 0.220
positive regulation of nuclear transcribed mrna poly a tail shortening GO:0060213 4 0.216
digestive system development GO:0055123 200 0.213
single organism cell adhesion GO:0098602 156 0.212
canonical wnt signaling pathway GO:0060070 130 0.211
Mouse
cell fate commitment GO:0045165 210 0.209
Mouse
jnk cascade GO:0007254 72 0.207
heart morphogenesis GO:0003007 178 0.203
negative regulation of cell proliferation GO:0008285 296 0.200
Mouse
heart growth GO:0060419 45 0.199
Mouse
negative regulation of fat cell differentiation GO:0045599 36 0.198
cellular response to organonitrogen compound GO:0071417 145 0.196
response to acid chemical GO:0001101 111 0.192
rhythmic process GO:0048511 174 0.190
positive regulation of t cell differentiation GO:0045582 52 0.190
Mouse
pharynx development GO:0060465 1 0.187
schwann cell development GO:0014044 22 0.186
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 18 0.186
cranial nerve development GO:0021545 41 0.185
regulation of cellular amino acid metabolic process GO:0006521 5 0.183
regulation of inflammatory response GO:0050727 147 0.183
forebrain development GO:0030900 302 0.181
cellular response to cytokine stimulus GO:0071345 189 0.180
cytokine mediated signaling pathway GO:0019221 115 0.179
positive regulation of t helper 1 cell differentiation GO:0045627 4 0.178
regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061418 2 0.177
Mouse
female gonad development GO:0008585 71 0.177
Mouse
nucleocytoplasmic transport GO:0006913 139 0.176
regulation of establishment of protein localization GO:0070201 181 0.175
mesenchyme development GO:0060485 152 0.175
Mouse
stem cell differentiation GO:0048863 268 0.171
myeloid cell differentiation GO:0030099 233 0.169
positive regulation of apoptotic process GO:0043065 217 0.169
regulation of mapk cascade GO:0043408 248 0.166
Worm
negative regulation of defense response GO:0031348 77 0.165
regulation of canonical wnt signaling pathway GO:0060828 82 0.164
Mouse
kidney morphogenesis GO:0060993 83 0.164
Mouse
phagocytosis GO:0006909 66 0.162
Fly
heterocycle catabolic process GO:0046700 280 0.162
osteoclast differentiation GO:0030316 62 0.161
kidney development GO:0001822 213 0.157
Mouse
response to camp GO:0051591 14 0.157
nephron tubule morphogenesis GO:0072078 68 0.156
Mouse
chromatin organization GO:0006325 206 0.156
negative regulation of inflammatory response GO:0050728 61 0.156
positive regulation of epithelial cell proliferation GO:0050679 68 0.154
t cell activation GO:0042110 289 0.154
Mouse
epithelial tube morphogenesis GO:0060562 303 0.154
Mouse
central nervous system neuron development GO:0021954 67 0.150
rhombomere formation GO:0021594 1 0.149
positive regulation of fibroblast proliferation GO:0048146 20 0.148
axon regeneration GO:0031103 12 0.147
negative regulation of cell cycle process GO:0010948 69 0.147
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 28 0.147
negative regulation of immune system process GO:0002683 209 0.145
development of primary sexual characteristics GO:0045137 143 0.142
Mouse
fibroblast proliferation GO:0048144 35 0.142
regulation of t cell activation GO:0050863 170 0.141
Mouse
negative regulation of cell cycle phase transition GO:1901988 48 0.141
regulation of apoptotic signaling pathway GO:2001233 197 0.139
regulation of osteoblast differentiation GO:0045667 67 0.139
motor neuron axon guidance GO:0008045 26 0.138
cellular amine metabolic process GO:0044106 44 0.137
cellular response to growth factor stimulus GO:0071363 197 0.137
regulation of mitotic cell cycle phase transition GO:1901990 73 0.136
brain segmentation GO:0035284 3 0.135
locomotory behavior GO:0007626 195 0.132
response to heparin GO:0071503 1 0.131
membrane organization GO:0061024 245 0.131
genitalia development GO:0048806 37 0.129
Mouse
cellular response to follicle stimulating hormone stimulus GO:0071372 1 0.127
protein catabolic process GO:0030163 221 0.127
regulation of neuron differentiation GO:0045664 281 0.127
protein import into nucleus GO:0006606 95 0.127
response to peptide hormone GO:0043434 127 0.127
Mouse Rat
regulation of protein deacetylation GO:0090311 17 0.126
vitellogenesis GO:0007296 2 0.125
response to interleukin 1 GO:0070555 11 0.123
regulation of epithelial cell proliferation GO:0050678 141 0.122
cell type specific apoptotic process GO:0097285 268 0.122
Mouse
developmental growth involved in morphogenesis GO:0060560 138 0.122
cranial nerve morphogenesis GO:0021602 26 0.120
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.120
cellular response to extracellular stimulus GO:0031668 81 0.120
stress activated protein kinase signaling cascade GO:0031098 81 0.119
negative regulation of cellular protein metabolic process GO:0032269 247 0.119
Worm
immune effector process GO:0002252 321 0.118
placenta blood vessel development GO:0060674 31 0.118
cellular response to dna damage stimulus GO:0006974 207 0.117
gamma delta t cell activation GO:0046629 13 0.117
Mouse
response to transforming growth factor beta GO:0071559 88 0.116
olfactory lobe development GO:0021988 32 0.116
regulation of response to wounding GO:1903034 189 0.114
olfactory bulb development GO:0021772 30 0.112
epidermis development GO:0008544 187 0.111
response to organic cyclic compound GO:0014070 198 0.111
inflammatory response GO:0006954 244 0.110
embryonic viscerocranium morphogenesis GO:0048703 8 0.109
cellular response to heparin GO:0071504 1 0.108
oocyte differentiation GO:0009994 35 0.107
Worm
regulation of organelle organization GO:0033043 289 0.107
neuron apoptotic process GO:0051402 142 0.106
posterior mesonephric tubule development GO:0072166 2 0.106
Mouse
embryonic placenta development GO:0001892 98 0.105
integrin mediated signaling pathway GO:0007229 27 0.104
glial cell development GO:0021782 54 0.104
Zebrafish
regulation of organ growth GO:0046620 61 0.103
Mouse
nephron epithelium morphogenesis GO:0072088 68 0.103
Mouse
multi multicellular organism process GO:0044706 109 0.102
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.101
negative regulation of protein modification process GO:0031400 163 0.101
Worm
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.101
muscle system process GO:0003012 141 0.101
cellular response to calcium ion GO:0071277 14 0.099
germ cell development GO:0007281 185 0.099
Mouse Worm
cellular ketone metabolic process GO:0042180 84 0.099
positive regulation of myeloid leukocyte differentiation GO:0002763 26 0.098
regulation of glomerulus development GO:0090192 6 0.098
Mouse
pericardium development GO:0060039 16 0.098
Mouse
positive regulation of innate immune response GO:0045089 80 0.098
glomerulus development GO:0032835 40 0.097
Mouse
negative regulation of cellular amine metabolic process GO:0033239 1 0.097
amine metabolic process GO:0009308 45 0.096
branching morphogenesis of an epithelial tube GO:0048754 159 0.096
Mouse
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.096
Worm
cellular response to insulin stimulus GO:0032869 78 0.095
cellular response to external stimulus GO:0071496 88 0.095
central nervous system morphogenesis GO:0021551 2 0.095
regulation of chromosome organization GO:0033044 83 0.095
sertoli cell differentiation GO:0060008 18 0.094
Mouse
establishment of protein localization to organelle GO:0072594 118 0.094
negative regulation of wnt signaling pathway GO:0030178 73 0.094
Mouse
regulation of fibroblast proliferation GO:0048145 34 0.094
regulation of peptidase activity GO:0052547 96 0.093
regulation of gamma delta t cell activation GO:0046643 9 0.093
Mouse
carbohydrate transport GO:0008643 62 0.092
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.091
regulation of protein sumoylation GO:0033233 4 0.090
positive regulation of rho gtpase activity GO:0032321 41 0.090
circadian rhythm GO:0007623 114 0.090
apoptotic signaling pathway GO:0097190 306 0.089
central nervous system neuron axonogenesis GO:0021955 28 0.089
positive regulation of transcription from rna polymerase i promoter GO:0045943 3 0.089
regulation of proteolysis GO:0030162 164 0.089
mitotic cell cycle checkpoint GO:0007093 31 0.088
positive regulation of cell development GO:0010720 237 0.088
mesonephric epithelium development GO:0072163 94 0.088
Mouse
regulation of lymphocyte activation GO:0051249 240 0.088
Mouse
ovulation GO:0030728 15 0.087
Worm
negative regulation of multi organism process GO:0043901 68 0.087
Worm
glycosyl compound metabolic process GO:1901657 246 0.085
angiogenesis GO:0001525 201 0.085
branching involved in ureteric bud morphogenesis GO:0001658 56 0.085
Mouse
response to amino acid GO:0043200 37 0.085
ureteric bud morphogenesis GO:0060675 62 0.084
Mouse
positive regulation of nucleotide metabolic process GO:0045981 114 0.083
nucleotide metabolic process GO:0009117 332 0.083
central nervous system neuron differentiation GO:0021953 162 0.083
regulation of glomerular mesangial cell proliferation GO:0072124 1 0.083
Mouse
negative regulation of lymphocyte differentiation GO:0045620 32 0.083
cell differentiation involved in kidney development GO:0061005 33 0.083
Mouse
positive regulation of apoptotic signaling pathway GO:2001235 95 0.082
regulation of dna templated transcription in response to stress GO:0043620 9 0.082
Mouse
regulation of heart growth GO:0060420 31 0.081
Mouse
regulation of neuronal synaptic plasticity GO:0048168 30 0.081
Rat
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.080
protein localization to organelle GO:0033365 185 0.079
cytokine production GO:0001816 319 0.079
nucleoside phosphate metabolic process GO:0006753 338 0.079
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900153 5 0.079
synapse organization GO:0050808 125 0.079
negative regulation of mesenchymal cell apoptotic process involved in metanephros development GO:1900212 4 0.078
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.078
Mouse
regulation of translation GO:0006417 71 0.078
autonomic nervous system development GO:0048483 43 0.078
reactive oxygen species biosynthetic process GO:1903409 8 0.078
neural tube development GO:0021915 160 0.077
cell maturation GO:0048469 127 0.076
Worm
positive regulation of inflammatory response GO:0050729 47 0.076
regulation of chromatin modification GO:1903308 57 0.076
regulation of protein transport GO:0051223 163 0.076
adult behavior GO:0030534 135 0.076
regulation of intracellular transport GO:0032386 159 0.076
positive regulation of proteolysis GO:0045862 85 0.076
regulation of metanephric glomerulus development GO:0072298 5 0.075
Mouse
cellular response to hormone stimulus GO:0032870 150 0.075
negative regulation of nf kappab transcription factor activity GO:0032088 15 0.075
response to purine containing compound GO:0014074 28 0.075
single fertilization GO:0007338 82 0.074
Mouse
organ growth GO:0035265 117 0.074
Mouse
epithelial tube formation GO:0072175 130 0.074
regulation of leukocyte apoptotic process GO:2000106 56 0.074
negative regulation of t cell differentiation GO:0045581 23 0.073
purine nucleoside triphosphate catabolic process GO:0009146 203 0.073
regulation of cell cycle phase transition GO:1901987 77 0.073
single organismal cell cell adhesion GO:0016337 131 0.073
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.072
cellular amino acid metabolic process GO:0006520 103 0.072
cellular response to ionizing radiation GO:0071479 11 0.071
Mouse
cellular response to antibiotic GO:0071236 4 0.071
humoral immune response GO:0006959 57 0.071
response to lipopolysaccharide GO:0032496 128 0.071
negative regulation of leukocyte differentiation GO:1902106 51 0.071
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 8 0.071
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.071
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 25 0.070
hippocampus development GO:0021766 52 0.070
preganglionic parasympathetic nervous system development GO:0021783 17 0.069
fertilization GO:0009566 127 0.069
Mouse
rna splicing GO:0008380 54 0.069
Mouse
forebrain cell migration GO:0021885 58 0.069
negative regulation of protein kinase activity by regulation of protein phosphorylation GO:0044387 2 0.068
intrinsic apoptotic signaling pathway GO:0097193 132 0.068
osteoblast development GO:0002076 17 0.068
regulation of cell migration GO:0030334 219 0.068
regulation of neuron projection development GO:0010975 169 0.068
mesonephric tubule development GO:0072164 94 0.068
Mouse
regulation of cysteine type endopeptidase activity GO:2000116 65 0.067
ureteric bud development GO:0001657 94 0.067
Mouse
negative regulation of neuron apoptotic process GO:0043524 92 0.067
response to drug GO:0042493 75 0.066
proteoglycan metabolic process GO:0006029 38 0.066
positive regulation of reproductive process GO:2000243 19 0.066
Mouse
olfactory learning GO:0008355 2 0.066
purine ribonucleotide catabolic process GO:0009154 208 0.066
negative regulation of mitotic cell cycle GO:0045930 58 0.065
regulation of mitotic cell cycle GO:0007346 126 0.065
neuron projection guidance GO:0097485 141 0.065
male gamete generation GO:0048232 285 0.065
Mouse
carbohydrate metabolic process GO:0005975 230 0.065
maintenance of location GO:0051235 89 0.065
regulation of lymphocyte differentiation GO:0045619 107 0.065
Mouse
long term synaptic potentiation GO:0060291 25 0.063
nephron epithelium development GO:0072009 92 0.063
Mouse
positive regulation of cytokine production GO:0001819 174 0.063
cardiac cell fate commitment GO:0060911 10 0.063
Mouse
cell cycle g1 s phase transition GO:0044843 57 0.063
cellular homeostasis GO:0019725 240 0.063
cellular response to abiotic stimulus GO:0071214 56 0.062
Mouse
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.062
interleukin 1 mediated signaling pathway GO:0070498 4 0.062
purine nucleotide metabolic process GO:0006163 302 0.062
positive regulation of histone modification GO:0031058 28 0.062
development of primary female sexual characteristics GO:0046545 73 0.062
Mouse
negative regulation of neuron death GO:1901215 98 0.062
divalent inorganic cation transport GO:0072511 178 0.062
male sex differentiation GO:0046661 109 0.061
Mouse
response to insulin GO:0032868 100 0.061
Mouse Rat
regulation of organ morphogenesis GO:2000027 144 0.061
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.061
Worm
nephron development GO:0072006 109 0.060
Mouse
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 23 0.060
hexose metabolic process GO:0019318 98 0.060
posttranscriptional regulation of gene expression GO:0010608 155 0.060
response to amine GO:0014075 16 0.060
cellular nitrogen compound catabolic process GO:0044270 280 0.059
t cell proliferation GO:0042098 120 0.059
positive regulation of cell adhesion GO:0045785 80 0.059
metanephric nephron morphogenesis GO:0072273 19 0.059
Mouse
regulation of cytokine production GO:0001817 266 0.059
cardiac muscle cell differentiation GO:0055007 69 0.059
Mouse
positive regulation of myeloid cell differentiation GO:0045639 43 0.059
t cell activation involved in immune response GO:0002286 43 0.059
regulation of cell cycle process GO:0010564 160 0.059
cellular response to amino acid stimulus GO:0071230 29 0.059
sequestering of metal ion GO:0051238 19 0.058
mesonephros development GO:0001823 97 0.058
Mouse
intracellular protein transport GO:0006886 204 0.058
metencephalon development GO:0022037 89 0.058
negative regulation of intracellular steroid hormone receptor signaling pathway GO:0033144 11 0.058
glomerular mesangial cell proliferation GO:0072110 3 0.058
Mouse
mitotic g2 dna damage checkpoint GO:0007095 8 0.058
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.057
oocyte axis specification GO:0007309 2 0.057
sensory organ morphogenesis GO:0090596 242 0.057
oocyte development GO:0048599 33 0.057
Worm
mammary gland morphogenesis GO:0060443 54 0.056
aromatic compound catabolic process GO:0019439 286 0.056
morphogenesis of a branching structure GO:0001763 203 0.056
Mouse
hepaticobiliary system development GO:0061008 67 0.056
positive regulation of hydrolase activity GO:0051345 148 0.056
response to catecholamine GO:0071869 4 0.056
positive regulation of organelle organization GO:0010638 128 0.056
purine containing compound metabolic process GO:0072521 311 0.055
proteasomal protein catabolic process GO:0010498 98 0.055
positive regulation of male gonad development GO:2000020 6 0.055
Mouse
regulation of myeloid cell differentiation GO:0045637 96 0.055
metanephric s shaped body morphogenesis GO:0072284 2 0.055
Mouse
regulation of cell adhesion GO:0030155 154 0.055
forebrain neuron differentiation GO:0021879 52 0.055
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.055
regulation of hydrolase activity GO:0051336 246 0.054
positive regulation of transforming growth factor beta2 production GO:0032915 2 0.054
second messenger mediated signaling GO:0019932 73 0.054
dendrite development GO:0016358 115 0.054
pallium development GO:0021543 120 0.054
female gamete generation GO:0007292 74 0.054
Worm
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.054
leukocyte migration GO:0050900 124 0.054
regulation of neuron apoptotic process GO:0043523 122 0.054
regulation of intrinsic apoptotic signaling pathway in response to dna damage GO:1902229 14 0.054
cognition GO:0050890 149 0.054
Rat
cell adhesion GO:0007155 329 0.053
i kappab kinase nf kappab signaling GO:0007249 85 0.053
metanephric part of ureteric bud development GO:0035502 2 0.053
Mouse
nephron morphogenesis GO:0072028 69 0.053
Mouse
regulation of metal ion transport GO:0010959 106 0.052
glycosyl compound catabolic process GO:1901658 206 0.052
mesenchymal cell development GO:0014031 93 0.052
negative regulation of homeostatic process GO:0032845 71 0.052
wnt signaling pathway GO:0016055 188 0.052
Mouse
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 16 0.051
vascular process in circulatory system GO:0003018 62 0.051
positive regulation of heart growth GO:0060421 18 0.051
Mouse
response to ethanol GO:0045471 18 0.051
positive regulation of neuron apoptotic process GO:0043525 25 0.050
regulation of mesenchymal cell apoptotic process involved in metanephros development GO:1900211 4 0.050
Mouse
guanosine containing compound catabolic process GO:1901069 144 0.050
stem cell development GO:0048864 219 0.050
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.050
regulation of nucleotide metabolic process GO:0006140 169 0.050
hindbrain morphogenesis GO:0021575 46 0.050
Zebrafish
cell fate specification GO:0001708 72 0.050
regulation of neuron death GO:1901214 134 0.050
chorio allantoic fusion GO:0060710 8 0.050
myotube differentiation GO:0014902 105 0.050
regulation of leukocyte proliferation GO:0070663 121 0.050
cellular response to metal ion GO:0071248 31 0.050
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.050
rna processing GO:0006396 105 0.049
Mouse
synapse assembly GO:0007416 56 0.049
regulation of purine nucleotide catabolic process GO:0033121 122 0.049
chemokine production GO:0032602 34 0.049
regulation of cellular protein catabolic process GO:1903362 61 0.049
leukocyte proliferation GO:0070661 172 0.049
regulation of myotube differentiation GO:0010830 62 0.049
regulation of endothelial cell proliferation GO:0001936 23 0.049
mesenchymal cell differentiation GO:0048762 107 0.049
negative regulation of nervous system development GO:0051961 156 0.048
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.048
regulation of cell substrate adhesion GO:0010810 73 0.048
negative regulation of phosphorylation GO:0042326 166 0.048
Worm
circulatory system process GO:0003013 197 0.048
cellular response to gonadotropin stimulus GO:0071371 4 0.048
cardiac chamber morphogenesis GO:0003206 93 0.048
negative regulation of apoptotic signaling pathway GO:2001234 104 0.048
regulation of brown fat cell differentiation GO:0090335 5 0.048
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.048
sensory system development GO:0048880 3 0.047
Zebrafish
protein localization to nucleus GO:0034504 121 0.047
cell cycle checkpoint GO:0000075 47 0.047
muscle cell differentiation GO:0042692 261 0.047
Mouse
protein maturation GO:0051604 176 0.047
positive regulation of transferase activity GO:0051347 167 0.047
neuron death GO:0070997 154 0.046
response to alcohol GO:0097305 48 0.046
ubiquitin dependent protein catabolic process GO:0006511 129 0.046
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.046
positive regulation of protein catabolic process GO:0045732 60 0.046
nuclear export GO:0051168 34 0.046
early endosome to late endosome transport GO:0045022 2 0.046
nucleoside triphosphate catabolic process GO:0009143 205 0.045
neuromuscular process GO:0050905 99 0.045
regulation of reproductive process GO:2000241 66 0.045
Mouse Worm
kidney vasculature development GO:0061440 15 0.045
Mouse
regulation of nucleoside metabolic process GO:0009118 130 0.045
regulation of striated muscle cell differentiation GO:0051153 81 0.045
response to inorganic substance GO:0010035 96 0.045
negative regulation of mapk cascade GO:0043409 65 0.045
Worm
cd4 positive alpha beta t cell activation GO:0035710 45 0.045

Egr2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
neuromuscular disease DOID:440 0 0.473
Human
disease of anatomical entity DOID:7 0 0.473
Human
nervous system disease DOID:863 0 0.473
Human
neuropathy DOID:870 0 0.473
Human
charcot marie tooth disease DOID:10595 0 0.424
Human
cancer DOID:162 0 0.071
disease of cellular proliferation DOID:14566 0 0.071
organ system cancer DOID:0050686 0 0.071
physical disorder DOID:0080015 0 0.060
congenital nervous system abnormality DOID:2490 0 0.060
immune system disease DOID:2914 0 0.054