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Mus musculus

18 genes annotated in mouse

sertoli cell differentiation

The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "sertoli cell differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "sertoli cell differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
Pten	phosphatase and tensin homolog	0.993
Esr1	estrogen receptor 1 (alpha)	0.970	Rat
Pax2	paired box gene 2	0.962
Fgfr2	fibroblast growth factor receptor 2	0.952
Pax8	paired box gene 8	0.945
Pitx2	paired-like homeodomain transcription factor 2	0.910
Emx2	empty spiracles homolog 2 (Drosophila)	0.889
Gata4	GATA binding protein 4	0.882
Ar	androgen receptor	0.877
Kiss1	KiSS-1 metastasis-suppressor	0.832
Rxra	retinoid X receptor alpha	0.814
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.813
Isl1	ISL1 transcription factor, LIM/homeodomain	0.786
Nf1	neurofibromatosis 1	0.777
Fgf8	fibroblast growth factor 8	0.693
Arid4b	AT rich interactive domain 4B (RBP1-like)	0.605
Rarg	retinoic acid receptor, gamma	0.591	Mouse
Ntf3	neurotrophin 3	0.569
Lhx3	LIM homeobox protein 3	0.563
Amhr2	anti-Mullerian hormone type 2 receptor	0.540
Shh	sonic hedgehog	0.522
Apc	adenomatosis polyposis coli	0.500
Gli3	GLI-Kruppel family member GLI3	0.487
Gata6	GATA binding protein 6	0.471	Mouse
Bmp4	bone morphogenetic protein 4	0.453
Ret	ret proto-oncogene	0.452
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.407
Duox2	dual oxidase 2	0.398
Kiss1r	KISS1 receptor	0.393
Rarb	retinoic acid receptor, beta	0.368	Mouse
Fgf10	fibroblast growth factor 10	0.344
Sox9	SRY-box containing gene 9	0.329
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.327
Smc1a	structural maintenance of chromosomes 1A	0.323
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.318	Mouse
Nos3	nitric oxide synthase 3, endothelial cell	0.306
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.302
Pou5f1	POU domain, class 5, transcription factor 1	0.295
Tbx3	T-box 3	0.284
Hoxa1	homeobox A1	0.276
Arid4a	AT rich interactive domain 4A (RBP1-like)	0.261
Gdnf	glial cell line derived neurotrophic factor	0.250
Ahr	aryl-hydrocarbon receptor	0.246
Gata3	GATA binding protein 3	0.232	Mouse
Trp63	transformation related protein 63	0.226
Nr0b1	nuclear receptor subfamily 0, group B, member 1	0.213
Tbx1	T-box 1	0.199
Egr1	early growth response 1	0.193	Mouse
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.192
Ghr	growth hormone receptor	0.183
Bcl2	B-cell leukemia/lymphoma 2	0.180
Chd7	chromodomain helicase DNA binding protein 7	0.175
Tgfb2	transforming growth factor, beta 2	0.168
Tcfap2a	transcription factor AP-2, alpha	0.150
Cga	glycoprotein hormones, alpha subunit	0.148
Meox2	mesenchyme homeobox 2	0.145
Pax3	paired box gene 3	0.143
Mesp1	mesoderm posterior 1	0.142
Foxc1	forkhead box C1	0.138
Lef1	lymphoid enhancer binding factor 1	0.138
Vegfa	vascular endothelial growth factor A	0.136
Jag1	jagged 1	0.135
Rara	retinoic acid receptor, alpha	0.125
Sox4	SRY-box containing gene 4	0.119	Mouse
Eya1	eyes absent 1 homolog (Drosophila)	0.115
Hand1	heart and neural crest derivatives expressed transcript 1	0.114
Sall4	sal-like 4 (Drosophila)	0.103
Tcf21	transcription factor 21	0.101
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.100
Egr2	early growth response 2	0.094	Mouse
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.094
Fos	FBJ osteosarcoma oncogene	0.090
Hand2	heart and neural crest derivatives expressed transcript 2	0.090
Mecp2	methyl CpG binding protein 2	0.086
She	src homology 2 domain-containing transforming protein E	0.083
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.082	Mouse
Ctnnb1	catenin (cadherin associated protein), beta 1	0.081
Nrg1	neuregulin 1	0.077
Lhx1	LIM homeobox protein 1	0.074
Bdnf	brain derived neurotrophic factor	0.074
Inhba	inhibin beta-A	0.073
Plekha5	pleckstrin homology domain containing, family A member 5	0.073
Prlr	prolactin receptor	0.070
Hoxa2	homeobox A2	0.068
Msx2	homeobox, msh-like 2	0.065
Fgf3	fibroblast growth factor 3	0.064
Lmx1b	LIM homeobox transcription factor 1 beta	0.063
Hr	hairless	0.059
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.059
Ccl2	chemokine (C-C motif) ligand 2	0.059
Dhh	desert hedgehog	0.059
Mmp9	matrix metallopeptidase 9	0.058
Amh	anti-Mullerian hormone	0.058
Inha	inhibin alpha	0.058
Sema5b	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B	0.057
Wnt4	wingless-related MMTV integration site 4	0.057
Tcfap2c	transcription factor AP-2, gamma	0.057
Phox2b	paired-like homeobox 2b	0.056
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.054
Nab2	Ngfi-A binding protein 2	0.053
Dbp	D site albumin promoter binding protein	0.052
Foxc2	forkhead box C2	0.051
Hoxd11	homeobox D11	0.051
Foxf1a	forkhead box F1a	0.050
Igf2bp1	insulin-like growth factor 2 mRNA binding protein 1	0.049
Nkx2-1	NK2 homeobox 1	0.048
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.048
Pitx1	paired-like homeodomain transcription factor 1	0.048
Smad6	MAD homolog 6 (Drosophila)	0.047
Thrb	thyroid hormone receptor beta	0.047	Mouse
Fgf4	fibroblast growth factor 4	0.046
Sox2	SRY-box containing gene 2	0.046	Mouse
Fshr	follicle stimulating hormone receptor	0.044
Plac1	placental specific protein 1	0.043
Gli2	GLI-Kruppel family member GLI2	0.043
Tal1	T-cell acute lymphocytic leukemia 1	0.042
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.042
Gbx2	gastrulation brain homeobox 2	0.042
Cldn5	claudin 5	0.041
Zfpm2	zinc finger protein, multitype 2	0.040
Sall1	sal-like 1 (Drosophila)	0.040
Dusp9	dual specificity phosphatase 9	0.039
Irs2	insulin receptor substrate 2	0.036
Gata5	GATA binding protein 5	0.036	Mouse
Hoxd13	homeobox D13	0.035
Hoxa4	homeobox A4	0.035
Bmper	BMP-binding endothelial regulator	0.035
Col4a3	collagen, type IV, alpha 3	0.034
Alx4	aristaless-like homeobox 4	0.033
Hoxa11	homeobox A11	0.033
Kit	kit oncogene	0.033
Hoxb3	homeobox B3	0.033
Lepr	leptin receptor	0.033
Tpo	thyroid peroxidase	0.032
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.032
Foxl2	forkhead box L2	0.032
Ddx6	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6	0.032
Wnt6	wingless-related MMTV integration site 6	0.031
Inhbb	inhibin beta-B	0.031
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.030
Slc16a2	solute carrier family 16 (monocarboxylic acid transporters), member 2	0.030
Pou3f3	POU domain, class 3, transcription factor 3	0.030
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.030
Efnb2	ephrin B2	0.030
Fgfr3	fibroblast growth factor receptor 3	0.029
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.029
Sox7	SRY-box containing gene 7	0.028	Mouse
Insm1	insulinoma-associated 1	0.028
Pbx1	pre B-cell leukemia transcription factor 1	0.028
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.028
Apln	apelin	0.028
Ptgs2	prostaglandin-endoperoxide synthase 2	0.027
Hes1	hairy and enhancer of split 1 (Drosophila)	0.027
Ppara	peroxisome proliferator activated receptor alpha	0.027
Bmp7	bone morphogenetic protein 7	0.027
Chst8	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8	0.027
Lhx9	LIM homeobox protein 9	0.027
Edar	ectodysplasin-A receptor	0.027
Traf6	TNF receptor-associated factor 6	0.026
Bglap2	bone gamma-carboxyglutamate protein 2	0.025
Tbx2	T-box 2	0.025
Zfp445	zinc finger protein 445	0.025
Snai1	snail homolog 1 (Drosophila)	0.024
Egfr	epidermal growth factor receptor	0.024
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.024
Jun	Jun oncogene	0.024
Nanog	Nanog homeobox	0.024
Pax6	paired box gene 6	0.024
Lmx1a	LIM homeobox transcription factor 1 alpha	0.024
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.023
Fst	follistatin	0.023
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.023
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.023
Vgf	VGF nerve growth factor inducible	0.023
Trp53	transformation related protein 53	0.022
Bnc1	basonuclin 1	0.022
Eng	endoglin	0.022
Foxf2	forkhead box F2	0.022
Nr1d1	nuclear receptor subfamily 1, group D, member 1	0.021	Mouse
Hoxa5	homeobox A5	0.021
Fosb	FBJ osteosarcoma oncogene B	0.021
Tead3	TEA domain family member 3	0.021
Itm2c	integral membrane protein 2C	0.021
Twist2	twist homolog 2 (Drosophila)	0.021
Eif2c2	eukaryotic translation initiation factor 2C, 2	0.021
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.021
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.020
Nr5a2	nuclear receptor subfamily 5, group A, member 2	0.020
Axin2	axin2	0.020
Wnt9b	wingless-type MMTV integration site 9B	0.020
Ttc7	tetratricopeptide repeat domain 7	0.020
Hoxa10	homeobox A10	0.019
Foxg1	forkhead box G1	0.019
Pthlh	parathyroid hormone-like peptide	0.019
Edn3	endothelin 3	0.019
Ednra	endothelin receptor type A	0.019
Rasip1	Ras interacting protein 1	0.019
Pou3f1	POU domain, class 3, transcription factor 1	0.019
Junb	Jun-B oncogene	0.018
Ascl2	achaete-scute complex homolog 2 (Drosophila)	0.018
Efna4	ephrin A4	0.018
Dsg4	desmoglein 4	0.018
Psmd3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	0.018
Foxa1	forkhead box A1	0.018
Nrk	Nik related kinase	0.018
Foxn1	forkhead box N1	0.018
Alx3	aristaless-like homeobox 3	0.018
Nhlh2	nescient helix loop helix 2	0.017
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.017
Hoxb4	homeobox B4	0.017
Tgfa	transforming growth factor alpha	0.017
Tef	thyrotroph embryonic factor	0.017
Smad3	MAD homolog 3 (Drosophila)	0.017
Klf4	Kruppel-like factor 4 (gut)	0.017
Dll4	delta-like 4 (Drosophila)	0.017
Phlda2	pleckstrin homology-like domain, family A, member 2	0.016
Wt1	Wilms tumor 1 homolog	0.016
Sox11	SRY-box containing gene 11	0.016	Mouse
Phox2a	paired-like homeobox 2a	0.016
Nr6a1	nuclear receptor subfamily 6, group A, member 1	0.016
Epha1	Eph receptor A1	0.016
Socs3	suppressor of cytokine signaling 3	0.016
Hoxc8	homeobox C8	0.016
Robo3	roundabout homolog 3 (Drosophila)	0.016
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.016
Lrp2	low density lipoprotein receptor-related protein 2	0.016
Tshr	thyroid stimulating hormone receptor	0.015	Mouse
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.015
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.015
Hoxd10	homeobox D10	0.015
Zfp503	zinc finger protein 503	0.015
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.015
Ubc	ubiquitin C	0.015
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.015
Krt14	keratin 14	0.015
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.015
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.015
Ikzf1	IKAROS family zinc finger 1	0.015
Ece1	endothelin converting enzyme 1	0.015
Fuz	fuzzy homolog (Drosophila)	0.015
Prdm16	PR domain containing 16	0.015
Dll1	delta-like 1 (Drosophila)	0.014
Otx1	orthodenticle homolog 1 (Drosophila)	0.014
Utf1	undifferentiated embryonic cell transcription factor 1	0.014
Ncoa1	nuclear receptor coactivator 1	0.014
Npc1	Niemann Pick type C1	0.014
Kdr	kinase insert domain protein receptor	0.014
Klf3	Kruppel-like factor 3 (basic)	0.014
Nrtn	neurturin	0.014
Bcl6b	B-cell CLL/lymphoma 6, member B	0.014
Zfpm1	zinc finger protein, multitype 1	0.014
Dlx5	distal-less homeobox 5	0.014
Fbn2	fibrillin 2	0.014
Klhl24	kelch-like 24 (Drosophila)	0.014
Vangl2	vang-like 2 (van gogh, Drosophila)	0.014
Tgfbr1	transforming growth factor, beta receptor I	0.014
Hmga2	high mobility group AT-hook 2	0.014
Alx1	ALX homeobox 1	0.014
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.014
Zic3	zinc finger protein of the cerebellum 3	0.014
Dst	dystonin	0.014
Col2a1	collagen, type II, alpha 1	0.013
Tg	thyroglobulin	0.013
Ctsb	cathepsin B	0.013
Rbl2	retinoblastoma-like 2	0.013
Sct	secretin	0.013
Sfn	stratifin	0.013
Acadm	acyl-Coenzyme A dehydrogenase, medium chain	0.013
Star	steroidogenic acute regulatory protein	0.013
Sall3	sal-like 3 (Drosophila)	0.013
Sox17	SRY-box containing gene 17	0.013	Mouse
Rictor	RPTOR independent companion of MTOR, complex 2	0.013
Tbx10	T-box 10	0.013
Zbtb46	zinc finger and BTB domain containing 46	0.013
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.013
Arx	aristaless related homeobox	0.013
Ikbkap	inhibitor of kappa light polypeptide enhancer in B-cells, kinase complex-associated protein	0.013
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.013
Gna11	guanine nucleotide binding protein, alpha 11	0.013
Epha4	Eph receptor A4	0.013
Gsdma3	gasdermin A3	0.013
Zeb1	zinc finger E-box binding homeobox 1	0.013
Tbx4	T-box 4	0.012
Kl	klotho	0.012
Gli1	GLI-Kruppel family member GLI1	0.012
Gja4	gap junction protein, alpha 4	0.012
Dmrt1	doublesex and mab-3 related transcription factor 1	0.012
Epas1	endothelial PAS domain protein 1	0.012
Fosl2	fos-like antigen 2	0.012
Lhx6	LIM homeobox protein 6	0.012
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.012
Vdr	vitamin D receptor	0.012
Rdh10	retinol dehydrogenase 10 (all-trans)	0.012
Fgf9	fibroblast growth factor 9	0.012
Acvrl1	activin A receptor, type II-like 1	0.012
Irf6	interferon regulatory factor 6	0.012
2810474O19Rik	RIKEN cDNA 2810474O19 gene	0.012
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.011
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.011
Skil	SKI-like	0.011
Neurog3	neurogenin 3	0.011
Gnrh1	gonadotropin releasing hormone 1	0.011
Fzd4	frizzled homolog 4 (Drosophila)	0.011
Tert	telomerase reverse transcriptase	0.011
Nkx3-1	NK-3 transcription factor, locus 1 (Drosophila)	0.011
Vhl	von Hippel-Lindau tumor suppressor	0.011
Bmp6	bone morphogenetic protein 6	0.011
Tcf15	transcription factor 15	0.011
Slc34a2	solute carrier family 34 (sodium phosphate), member 2	0.011
Lama3	laminin, alpha 3	0.011
Lin28a	lin-28 homolog A (C. elegans)	0.011
Irx5	Iroquois related homeobox 5 (Drosophila)	0.011
Lefty2	left-right determination factor 2	0.011
Gdf11	growth differentiation factor 11	0.011
Onecut1	one cut domain, family member 1	0.011
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.011
Msx1	homeobox, msh-like 1	0.011
Gcom1	GRINL1A complex locus	0.011
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.011
Foxe1	forkhead box E1	0.011
Lats1	large tumor suppressor	0.011
Olig2	oligodendrocyte transcription factor 2	0.011
Tgfbr2	transforming growth factor, beta receptor II	0.011
Dusp1	dual specificity phosphatase 1	0.011
Adam17	a disintegrin and metallopeptidase domain 17	0.011
Prrx2	paired related homeobox 2	0.011
Foxd2	forkhead box D2	0.011
Hoxd3	homeobox D3	0.010
Acvr1	activin A receptor, type 1	0.010
Rimklb	ribosomal modification protein rimK-like family member B	0.010
Ier2	immediate early response 2	0.010
Esyt3	extended synaptotagmin-like protein 3	0.010
Hoxb6	homeobox B6	0.010
Notch1	Notch gene homolog 1 (Drosophila)	0.010
Hoxb5	homeobox B5	0.010
Supv3l1	suppressor of var1, 3-like 1 (S. cerevisiae)	0.010
Esrrb	estrogen related receptor, beta	0.010
Myo6	myosin VI	0.010
Esam	endothelial cell-specific adhesion molecule	0.010
Cd44	CD44 antigen	0.010
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.010
Cux1	cut-like homeobox 1	0.010
Prop1	paired like homeodomain factor 1	0.010
Smad7	MAD homolog 7 (Drosophila)	0.010
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.010
Dazl	deleted in azoospermia-like	0.010