Mus musculus

68 known processes

Tie1

tyrosine kinase with immunoglobulin-like and EGF-like domains 1

(Aliases: TIE,D430008P04Rik,tie-1)

Tie1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:0035793 1 0.912
regulation of vasculogenesis GO:2001212 9 0.908
cell migration involved in coronary angiogenesis GO:0060981 1 0.907
positive regulation of metanephric mesenchymal cell migration GO:2000591 1 0.843
heart trabecula formation GO:0060347 14 0.819
Mouse
melanocyte migration GO:0097324 2 0.797
cytokine production involved in immune response GO:0002367 34 0.791
Mouse
amine metabolic process GO:0009308 45 0.769
single organismal cell cell adhesion GO:0016337 131 0.745
Zebrafish Mouse
regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:1900238 1 0.744
smooth muscle cell chemotaxis GO:0071670 2 0.735
regulation of cellular ketone metabolic process GO:0010565 66 0.727
positive regulation of cellular amine metabolic process GO:0033240 5 0.721
response to erythropoietin GO:0036017 1 0.720
negative regulation of endothelial cell apoptotic process GO:2000352 7 0.715
Mouse
regulation of blood vessel remodeling GO:0060312 3 0.712
dendritic cell cytokine production GO:0002371 3 0.711
single organism cell adhesion GO:0098602 156 0.684
Zebrafish Mouse
macrophage colony stimulating factor signaling pathway GO:0038145 2 0.641
cell type specific apoptotic process GO:0097285 268 0.591
Mouse
blood vessel morphogenesis GO:0048514 285 0.567
cellular response to stem cell factor stimulus GO:0036216 3 0.562
metanephric glomerular mesangium development GO:0072223 3 0.544
sensory perception of mechanical stimulus GO:0050954 107 0.535
tissue migration GO:0090130 68 0.527
platelet derived growth factor receptor beta signaling pathway GO:0035791 4 0.521
calcium mediated signaling using intracellular calcium source GO:0035584 3 0.501
regulation of secretion GO:0051046 274 0.472
Mouse
cellular ketone metabolic process GO:0042180 84 0.469
regulation of endothelial cell migration GO:0010594 22 0.465
cell migration involved in vasculogenesis GO:0035441 2 0.456
negative regulation of cell migration GO:0030336 59 0.447
regulation of metanephric mesenchymal cell migration GO:2000589 2 0.441
regulation of vasculature development GO:1901342 88 0.429
wound healing GO:0042060 157 0.422
pro t cell differentiation GO:0002572 3 0.405
developmental maturation GO:0021700 193 0.398
metanephric mesenchymal cell migration GO:0035789 2 0.397
regulation of endothelial cell apoptotic process GO:2000351 9 0.392
Mouse
negative regulation of cell proliferation GO:0008285 296 0.390
regulation of cellular amine metabolic process GO:0033238 20 0.374
cardiac cell fate specification GO:0060912 2 0.370
regulation of cardiac cell fate specification GO:2000043 1 0.367
embryonic organ morphogenesis GO:0048562 276 0.363
cellular amino acid metabolic process GO:0006520 103 0.348
metanephric glomerular mesangial cell proliferation involved in metanephros development GO:0072262 3 0.347
cellular phosphate ion homeostasis GO:0030643 2 0.346
regulation of cellular amino acid metabolic process GO:0006521 5 0.344
regulation of actin filament based process GO:0032970 99 0.336
regulation of hormone levels GO:0010817 211 0.332
kit signaling pathway GO:0038109 3 0.319
cellular response to thyroid hormone stimulus GO:0097067 1 0.319
ameboidal type cell migration GO:0001667 128 0.318
cell migration involved in kidney development GO:0035787 3 0.315
nephron development GO:0072006 109 0.309
regulation of hippo signaling GO:0035330 1 0.306
smooth muscle tissue development GO:0048745 22 0.303
detection of mechanical stimulus involved in sensory perception GO:0050974 23 0.302
cellular amine metabolic process GO:0044106 44 0.302
endocardium development GO:0003157 10 0.295
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.294
angiogenesis GO:0001525 201 0.293
retina development in camera type eye GO:0060041 119 0.283
detection of mechanical stimulus involved in sensory perception of sound GO:0050910 16 0.282
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.278
phosphatidylinositol metabolic process GO:0046488 45 0.275
sensory perception of sound GO:0007605 97 0.270
positive regulation of vasculogenesis GO:2001214 7 0.267
positive regulation of bmp signaling pathway GO:0030513 23 0.267
muscle tissue development GO:0060537 308 0.265
positive regulation of mapk cascade GO:0043410 170 0.264
cellular homeostasis GO:0019725 240 0.263
mapk cascade GO:0000165 281 0.262
protein kinase b signaling GO:0043491 74 0.262
glomerular capillary formation GO:0072104 6 0.260
small gtpase mediated signal transduction GO:0007264 97 0.259
glomerulus development GO:0032835 40 0.253
skeletal muscle organ development GO:0060538 163 0.253
cell adhesion GO:0007155 329 0.253
Zebrafish Mouse
sprouting angiogenesis GO:0002040 26 0.252
melanocyte adhesion GO:0097326 1 0.250
epithelium migration GO:0090132 63 0.249
male gamete generation GO:0048232 285 0.248
mitral valve morphogenesis GO:0003183 4 0.247
pro b cell differentiation GO:0002328 10 0.247
metanephric glomerulus morphogenesis GO:0072275 3 0.247
response to macrophage colony stimulating factor GO:0036005 3 0.243
metanephric glomerulus vasculature morphogenesis GO:0072276 3 0.242
metanephric glomerular capillary formation GO:0072277 3 0.241
cardiac endothelial cell differentiation GO:0003348 4 0.240
homeostasis of number of cells GO:0048872 210 0.240
cardiac chamber morphogenesis GO:0003206 93 0.239
Mouse
detection of stimulus GO:0051606 84 0.238
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.237
epithelial cell migration GO:0010631 63 0.231
regulation of cell adhesion GO:0030155 154 0.229
Mouse
epithelial tube morphogenesis GO:0060562 303 0.227
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.227
cellular response to erythropoietin GO:0036018 1 0.226
myeloid cell differentiation GO:0030099 233 0.224
erythrocyte differentiation GO:0030218 88 0.224
phosphatidylinositol mediated signaling GO:0048015 41 0.222
regulation of cell migration GO:0030334 219 0.219
cellular chemical homeostasis GO:0055082 215 0.217
regulation of cell motility GO:2000145 236 0.216
rac protein signal transduction GO:0016601 13 0.216
t cell activation GO:0042110 289 0.215
negative regulation of immune system process GO:0002683 209 0.215
camera type eye development GO:0043010 266 0.215
positive regulation of cell migration GO:0030335 109 0.214
epithelial cell proliferation GO:0050673 174 0.214
Mouse
kidney vasculature development GO:0061440 15 0.213
negative regulation of glial cell proliferation GO:0060253 4 0.210
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.207
metanephric glomerulus development GO:0072224 13 0.202
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.201
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.200
negative regulation of endothelial cell migration GO:0010596 4 0.198
renal system development GO:0072001 225 0.194
epithelial cell proliferation involved in prostatic bud elongation GO:0060517 1 0.193
vascular process in circulatory system GO:0003018 62 0.193
ascending aorta development GO:0035905 3 0.189
erythropoietin mediated signaling pathway GO:0038162 1 0.189
endocardial cell differentiation GO:0060956 4 0.189
sensory organ morphogenesis GO:0090596 242 0.186
detection of mechanical stimulus involved in equilibrioception GO:0050973 2 0.184
response to stem cell factor GO:0036215 3 0.184
apical junction assembly GO:0043297 15 0.179
lymphocyte differentiation GO:0030098 242 0.178
cellular response to monosaccharide stimulus GO:0071326 47 0.176
ascending aorta morphogenesis GO:0035910 3 0.176
tripeptide transport GO:0042939 1 0.176
blood circulation GO:0008015 195 0.175
negative regulation of mesodermal cell fate specification GO:0042662 3 0.173
cell migration involved in endocardial cushion formation GO:0003273 3 0.169
regulation of epithelial cell migration GO:0010632 35 0.167
mitral valve development GO:0003174 4 0.166
cell cell adhesion GO:0098609 41 0.165
cell migration involved in sprouting angiogenesis GO:0002042 9 0.163
glycerolipid metabolic process GO:0046486 122 0.159
angiogenesis involved in coronary vascular morphogenesis GO:0060978 2 0.159
cellular response to vascular endothelial growth factor stimulus GO:0035924 11 0.158
ion transmembrane transport GO:0034220 361 0.158
cellular response to peptide GO:1901653 92 0.157
negative regulation of blood vessel endothelial cell migration GO:0043537 3 0.157
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.157
endothelial cell apoptotic process GO:0072577 9 0.155
Mouse
endothelial cell migration GO:0043542 44 0.155
vascular endothelial growth factor receptor signaling pathway GO:0048010 24 0.154
positive regulation of protein phosphorylation GO:0001934 242 0.154
Mouse
negative regulation of b cell differentiation GO:0045578 4 0.154
regulation of epithelial cell proliferation GO:0050678 141 0.153
regulation of reactive oxygen species metabolic process GO:2000377 40 0.152
regulation of transferase activity GO:0051338 263 0.151
sensory perception GO:0007600 245 0.151
multicellular organismal homeostasis GO:0048871 164 0.151
response to thyroid hormone GO:0097066 2 0.150
cytokine mediated signaling pathway GO:0019221 115 0.149
development of primary sexual characteristics GO:0045137 143 0.149
ruffle organization GO:0031529 16 0.147
cell cell junction organization GO:0045216 72 0.147
embryonic heart tube development GO:0035050 65 0.146
gland development GO:0048732 330 0.146
kidney development GO:0001822 213 0.145
spermatogenesis GO:0007283 284 0.145
pigmentation GO:0043473 71 0.144
germ cell development GO:0007281 185 0.144
positive regulation of cell motility GO:2000147 116 0.143
leukocyte differentiation GO:0002521 342 0.141
nucleotide catabolic process GO:0009166 217 0.140
intrahepatic bile duct development GO:0035622 2 0.140
liver development GO:0001889 66 0.140
regulation of actin cytoskeleton organization GO:0032956 84 0.139
transmembrane transport GO:0055085 412 0.138
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.138
retina morphogenesis in camera type eye GO:0060042 45 0.137
positive regulation of angiogenesis GO:0045766 46 0.137
regulation of kinase activity GO:0043549 249 0.136
glucose homeostasis GO:0042593 128 0.135
immature b cell differentiation GO:0002327 10 0.134
positive regulation of smooth muscle cell migration GO:0014911 4 0.133
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 30 0.133
regulation of cell proliferation involved in tissue homeostasis GO:0060784 1 0.132
cellular response to amino acid stimulus GO:0071230 29 0.131
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 20 0.131
cellular response to dna damage stimulus GO:0006974 207 0.130
regulation of blood pressure GO:0008217 93 0.129
basement membrane assembly GO:0070831 2 0.129
g protein coupled receptor signaling pathway GO:0007186 243 0.129
neuron projection guidance GO:0097485 141 0.128
regulation of secretion by cell GO:1903530 249 0.128
Mouse
endothelial cell differentiation GO:0045446 41 0.126
negative regulation of platelet derived growth factor receptor signaling pathway GO:0010642 7 0.126
muscle cell differentiation GO:0042692 261 0.125
cell junction organization GO:0034330 77 0.125
inositol lipid mediated signaling GO:0048017 41 0.125
megakaryocyte differentiation GO:0030219 26 0.124
cardiocyte differentiation GO:0035051 87 0.124
appendage morphogenesis GO:0035107 149 0.124
regulation of protein kinase b signaling GO:0051896 56 0.123
circulatory system process GO:0003013 197 0.121
bronchus cartilage development GO:0060532 2 0.120
photoreceptor cell differentiation GO:0046530 52 0.120
regulation of rho gtpase activity GO:0032319 58 0.119
digestive tract morphogenesis GO:0048546 147 0.119
regulation of cell migration involved in sprouting angiogenesis GO:0090049 4 0.119
spermatid differentiation GO:0048515 115 0.119
metal ion homeostasis GO:0055065 189 0.118
septum primum development GO:0003284 4 0.118
retina vasculature development in camera type eye GO:0061298 17 0.117
cardiogenic plate morphogenesis GO:0003142 1 0.117
detection of external stimulus GO:0009581 61 0.116
morphogenesis of a branching structure GO:0001763 203 0.116
av node cell to bundle of his cell communication GO:0086067 2 0.115
adherens junction assembly GO:0034333 22 0.114
cardiac cell development GO:0055006 41 0.114
morphogenesis of a branching epithelium GO:0061138 193 0.114
insulin secretion GO:0030073 89 0.114
cardiac muscle fiber development GO:0048739 4 0.113
renal system vasculature morphogenesis GO:0061438 7 0.113
response to acid chemical GO:0001101 111 0.113
immune effector process GO:0002252 321 0.112
Mouse
cellular response to carbohydrate stimulus GO:0071322 50 0.109
endodermal cell fate specification GO:0001714 4 0.109
inflammatory response GO:0006954 244 0.109
digestive tract development GO:0048565 190 0.108
male germ line sex determination GO:0019100 2 0.107
positive regulation of cell development GO:0010720 237 0.107
regulation of cell projection organization GO:0031344 206 0.107
astrocyte fate commitment GO:0060018 4 0.107
negative regulation of cell motility GO:2000146 61 0.107
regulation of hydrolase activity GO:0051336 246 0.106
organelle assembly GO:0070925 177 0.106
regulation of lens epithelial cell proliferation GO:2001109 1 0.106
regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014717 3 0.105
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.104
embryonic skeletal system morphogenesis GO:0048704 91 0.103
cellular glucose homeostasis GO:0001678 52 0.103
artery development GO:0060840 53 0.102
intracellular protein transport GO:0006886 204 0.101
Mouse
cardiac ventricle morphogenesis GO:0003208 50 0.101
negative regulation of leukocyte differentiation GO:1902106 51 0.100
positive regulation of lens epithelial cell proliferation GO:2001111 1 0.099
cellular response to growth factor stimulus GO:0071363 197 0.099
detection of stimulus involved in sensory perception GO:0050906 44 0.099
calcium ion homeostasis GO:0055074 127 0.098
skeletal system morphogenesis GO:0048705 203 0.098
cell maturation GO:0048469 127 0.096
protein autophosphorylation GO:0046777 61 0.096
regulation of cellular component biogenesis GO:0044087 181 0.096
metanephric mesangial cell differentiation GO:0072209 1 0.096
endodermal cell fate determination GO:0007493 2 0.096
purine nucleoside catabolic process GO:0006152 205 0.096
lymphoid progenitor cell differentiation GO:0002320 17 0.095
central nervous system neuron differentiation GO:0021953 162 0.094
skeletal muscle fiber development GO:0048741 58 0.093
osteoclast differentiation GO:0030316 62 0.093
cell junction assembly GO:0034329 52 0.092
blood vessel endothelial cell migration GO:0043534 23 0.092
positive regulation of protein kinase b signaling GO:0051897 32 0.091
regulation of system process GO:0044057 200 0.091
closure of optic fissure GO:0061386 2 0.090
detection of abiotic stimulus GO:0009582 60 0.088
myeloid cell homeostasis GO:0002262 114 0.088
glycerophospholipid metabolic process GO:0006650 71 0.088
cell fate commitment GO:0045165 210 0.088
inner cell mass cellular morphogenesis GO:0001828 1 0.087
rhythmic process GO:0048511 174 0.087
axonogenesis GO:0007409 274 0.086
regulation of organelle organization GO:0033043 289 0.086
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.086
renal vesicle induction GO:0072034 3 0.085
t cell differentiation GO:0030217 174 0.085
extracellular matrix organization GO:0030198 147 0.085
lymph vessel morphogenesis GO:0036303 11 0.084
lung alveolus development GO:0048286 45 0.084
negative regulation of sodium ion transmembrane transport GO:1902306 1 0.083
venous blood vessel development GO:0060841 13 0.083
tissue homeostasis GO:0001894 115 0.083
cell substrate adhesion GO:0031589 130 0.083
Mouse
phosphatidylinositol 3 kinase signaling GO:0014065 36 0.083
regulation of peptide hormone secretion GO:0090276 75 0.082
regulation of cytoskeleton organization GO:0051493 122 0.082
response to amino acid GO:0043200 37 0.082
phospholipid metabolic process GO:0006644 87 0.081
ribose phosphate metabolic process GO:0019693 291 0.081
epithelial cell development GO:0002064 159 0.081
regulation of cell shape GO:0008360 39 0.080
sphingolipid metabolic process GO:0006665 45 0.080
b cell differentiation GO:0030183 78 0.080
blastocyst development GO:0001824 80 0.079
myeloid leukocyte differentiation GO:0002573 119 0.079
positive regulation of dna biosynthetic process GO:2000573 4 0.079
eye photoreceptor cell differentiation GO:0001754 41 0.079
positive regulation of kinase activity GO:0033674 155 0.078
vascular endothelial growth factor signaling pathway GO:0038084 10 0.078
response to retinoic acid GO:0032526 56 0.078
response to insulin GO:0032868 100 0.078
skeletal system development GO:0001501 356 0.078
kidney vasculature morphogenesis GO:0061439 7 0.077
lung development GO:0030324 164 0.077
peptidyl amino acid modification GO:0018193 336 0.077
Mouse
cardiac muscle cell development GO:0055013 39 0.075
hormone secretion GO:0046879 128 0.075
neuron projection extension GO:1990138 64 0.075
regulation of b cell differentiation GO:0045577 23 0.075
regulation of angiogenesis GO:0045765 81 0.075
prostate gland morphogenetic growth GO:0060737 4 0.075
regulation of ion transport GO:0043269 215 0.074
endocardium formation GO:0060214 4 0.074
positive regulation of secretion GO:0051047 130 0.073
Mouse
carbohydrate metabolic process GO:0005975 230 0.073
response to peptide GO:1901652 136 0.073
positive regulation of cell adhesion GO:0045785 80 0.073
Mouse
retinal rod cell differentiation GO:0060221 2 0.072
cation homeostasis GO:0055080 212 0.072
coronary vasculature morphogenesis GO:0060977 9 0.072
cognition GO:0050890 149 0.072
cell chemotaxis GO:0060326 81 0.072
determination of heart left right asymmetry GO:0061371 48 0.071
inner ear receptor cell differentiation GO:0060113 61 0.071
metanephric nephron development GO:0072210 34 0.071
humoral immune response GO:0006959 57 0.071
positive regulation of organelle organization GO:0010638 128 0.071
peptide secretion GO:0002790 114 0.071
inner ear morphogenesis GO:0042472 101 0.070
regulation of cytokine secretion involved in immune response GO:0002739 4 0.070
Mouse
embryonic digestive tract development GO:0048566 27 0.069
metanephric epithelium development GO:0072207 21 0.069
negative regulation of cellular protein metabolic process GO:0032269 247 0.069
positive regulation of endothelial cell proliferation GO:0001938 17 0.069
embryonic skeletal system development GO:0048706 120 0.069
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.068
spermatid development GO:0007286 108 0.068
striated muscle tissue development GO:0014706 293 0.068
pigment cell differentiation GO:0050931 27 0.067
cardiac atrium morphogenesis GO:0003209 23 0.067
stem cell proliferation GO:0072089 117 0.067
response to monosaccharide GO:0034284 67 0.067
regulation of map kinase activity GO:0043405 120 0.067
regulation of cell division GO:0051302 76 0.067
positive regulation of endothelial cell migration GO:0010595 12 0.066
positive regulation of epithelial cell migration GO:0010634 19 0.066
cellular response to cytokine stimulus GO:0071345 189 0.066
positive chemotaxis GO:0050918 18 0.066
aorta morphogenesis GO:0035909 22 0.066
cellular response to glucose stimulus GO:0071333 45 0.065
amide transport GO:0042886 138 0.065
nitrogen compound transport GO:0071705 271 0.065
muscle cell proliferation GO:0033002 52 0.065
glomerular mesangial cell proliferation GO:0072110 3 0.065
epithelial structure maintenance GO:0010669 9 0.065
negative regulation of phosphorus metabolic process GO:0010563 184 0.064
peptide transport GO:0015833 133 0.064
regulation of nucleoside metabolic process GO:0009118 130 0.064
stem cell development GO:0048864 219 0.064
cytokine secretion involved in immune response GO:0002374 6 0.064
Mouse
cellular response to macrophage colony stimulating factor stimulus GO:0036006 3 0.064
regulation of protein serine threonine kinase activity GO:0071900 157 0.064
peptidyl tyrosine autophosphorylation GO:0038083 5 0.064
peptidyl serine phosphorylation GO:0018105 74 0.064
Mouse
glomerular mesangial cell differentiation GO:0072008 3 0.063
detection of mechanical stimulus GO:0050982 27 0.063
endothelium development GO:0003158 45 0.063
cardiac atrium development GO:0003230 24 0.063
lamellipodium organization GO:0097581 29 0.063
aromatic compound catabolic process GO:0019439 286 0.062
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.062
second messenger mediated signaling GO:0019932 73 0.062
glycosyl compound catabolic process GO:1901658 206 0.062
cellular response to epidermal growth factor stimulus GO:0071364 4 0.062
cytokine production GO:0001816 319 0.062
Mouse
response to radiation GO:0009314 165 0.062
regulation of purine nucleotide catabolic process GO:0033121 122 0.061
hematopoietic progenitor cell differentiation GO:0002244 143 0.061
bmp signaling pathway GO:0030509 93 0.061
anatomical structure homeostasis GO:0060249 145 0.061
positive regulation of apoptotic process GO:0043065 217 0.061
regulation of neuron projection development GO:0010975 169 0.060
positive regulation of neuron differentiation GO:0045666 141 0.060
positive regulation of cell substrate adhesion GO:0010811 47 0.060
melanocyte differentiation GO:0030318 25 0.060
negative regulation of cellular component organization GO:0051129 194 0.060
regulation of blood vessel endothelial cell migration GO:0043535 12 0.060
glomerular mesangial cell development GO:0072144 3 0.060
leukocyte mediated immunity GO:0002443 174 0.059
regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 14 0.059
cardiac myofibril assembly GO:0055003 12 0.059
atrial septum primum morphogenesis GO:0003289 3 0.059
negative regulation of angiogenesis GO:0016525 25 0.059
cellular response to insulin stimulus GO:0032869 78 0.058
memory GO:0007613 58 0.058
inner cell mass cell differentiation GO:0001826 7 0.058
muscle fiber development GO:0048747 76 0.057
regulation of lymphocyte activation GO:0051249 240 0.057
regulation of muscle tissue development GO:1901861 97 0.057
male genitalia development GO:0030539 20 0.057
nephron tubule development GO:0072080 84 0.056
carbohydrate homeostasis GO:0033500 128 0.056
positive regulation of epithelial cell proliferation GO:0050679 68 0.056
guanosine containing compound catabolic process GO:1901069 144 0.056
neuromuscular process controlling balance GO:0050885 59 0.056
negative regulation of photoreceptor cell differentiation GO:0046533 4 0.056
diencephalon development GO:0021536 63 0.056
regulation of transmembrane transport GO:0034762 128 0.056
protein oligomerization GO:0051259 67 0.056
extracellular structure organization GO:0043062 148 0.056
cardiac chamber development GO:0003205 108 0.055
Mouse
regulation of bmp signaling pathway GO:0030510 60 0.055
positive regulation of protein modification process GO:0031401 299 0.055
Mouse
nucleoside phosphate catabolic process GO:1901292 222 0.055
negative regulation of neuron differentiation GO:0045665 101 0.055
cellular response to organonitrogen compound GO:0071417 145 0.055
regulation of mapk cascade GO:0043408 248 0.055
regulation of ion transmembrane transport GO:0034765 119 0.054
positive regulation of secretion by cell GO:1903532 114 0.054
Mouse
positive regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014718 2 0.054
tissue remodeling GO:0048771 102 0.054
muscle cell development GO:0055001 133 0.054
cellular response to acid chemical GO:0071229 68 0.054
actin cytoskeleton organization GO:0030036 220 0.054
locomotory behavior GO:0007626 195 0.054
response to oxygen levels GO:0070482 62 0.054
cation transport GO:0006812 399 0.053
metanephric glomerulus vasculature development GO:0072239 7 0.053
regulation of body fluid levels GO:0050878 162 0.053
hair cell differentiation GO:0035315 40 0.053
protein localization to organelle GO:0033365 185 0.053
Mouse
peptidyl tyrosine phosphorylation GO:0018108 143 0.053
Mouse
stem cell fate specification GO:0048866 3 0.053
luteinization GO:0001553 8 0.053
heart morphogenesis GO:0003007 178 0.053
Mouse
regulation of ras gtpase activity GO:0032318 88 0.052
cellular response to hormone stimulus GO:0032870 150 0.052
camera type eye photoreceptor cell differentiation GO:0060219 15 0.052
synapse organization GO:0050808 125 0.052
ear morphogenesis GO:0042471 118 0.052
positive regulation of jak stat cascade GO:0046427 22 0.052
negative regulation of lymphocyte activation GO:0051250 91 0.052
b cell activation GO:0042113 161 0.052
negative regulation of gastrulation GO:2000542 3 0.051
regulation of leukocyte differentiation GO:1902105 159 0.051
cellular response to hexose stimulus GO:0071331 47 0.051
regulation of branching involved in salivary gland morphogenesis by extracellular matrix epithelial cell signaling GO:0060668 1 0.051
glomerulus morphogenesis GO:0072102 10 0.051
focal adhesion assembly GO:0048041 19 0.051
mast cell differentiation GO:0060374 5 0.050
blood vessel remodeling GO:0001974 33 0.050
nucleoside triphosphate catabolic process GO:0009143 205 0.050
cardiac muscle tissue development GO:0048738 130 0.050
embryonic hemopoiesis GO:0035162 23 0.050
positive regulation of skeletal muscle tissue regeneration GO:0043415 4 0.050
prostate gland morphogenesis GO:0060512 32 0.050
regulation of peptidyl serine phosphorylation GO:0033135 39 0.050
Mouse
male gonad development GO:0008584 88 0.050
regulation of peptide secretion GO:0002791 77 0.049
epithelial cell cell adhesion GO:0090136 6 0.049
Zebrafish
divalent inorganic cation homeostasis GO:0072507 138 0.049
ovarian follicle development GO:0001541 40 0.049
leydig cell differentiation GO:0033327 10 0.049
cell migration involved in metanephros development GO:0035788 2 0.049
regulation of cell activation GO:0050865 289 0.049
chemotaxis GO:0006935 247 0.049
regulation of skeletal muscle fiber development GO:0048742 36 0.049
stem cell differentiation GO:0048863 268 0.048
respiratory tube development GO:0030323 167 0.048
peptide hormone secretion GO:0030072 109 0.048
cardiac muscle cell differentiation GO:0055007 69 0.048
regulation of response to wounding GO:1903034 189 0.048
regulation of b cell activation GO:0050864 81 0.048
blastocyst formation GO:0001825 33 0.048
production of molecular mediator of immune response GO:0002440 103 0.048
Mouse
germ line sex determination GO:0018992 3 0.048
limb development GO:0060173 166 0.048
cellular lipid metabolic process GO:0044255 323 0.048
dna biosynthetic process GO:0071897 22 0.048
purine ribonucleoside metabolic process GO:0046128 241 0.048
regulation of jak stat cascade GO:0046425 34 0.047
regulation of neuron differentiation GO:0045664 281 0.047
carbohydrate derivative biosynthetic process GO:1901137 183 0.047
response to organonitrogen compound GO:0010243 246 0.047
positive regulation of transferase activity GO:0051347 167 0.047
learning or memory GO:0007611 148 0.046
response to peptide hormone GO:0043434 127 0.046
calcium ion transport GO:0006816 159 0.046
noradrenergic neuron differentiation GO:0003357 6 0.046
regulation of gtp catabolic process GO:0033124 113 0.046
erk1 and erk2 cascade GO:0070371 77 0.046
regulation of rho protein signal transduction GO:0035023 71 0.046
cytokine secretion GO:0050663 72 0.046
Mouse

Tie1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.049
disease of anatomical entity DOID:7 0 0.049
blood coagulation disease DOID:1247 0 0.049
inherited blood coagulation disease DOID:2214 0 0.049
hematopoietic system disease DOID:74 0 0.049