IMP

Process View

Mus musculus

14 genes annotated in mouse

regulation of vascular endothelial growth factor receptor signaling pathway

Any process that modulates the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of vascular endothelial growth factor receptor signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of vascular endothelial growth factor receptor signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
Fgfr2	fibroblast growth factor receptor 2	0.776
Gli3	GLI-Kruppel family member GLI3	0.708
Ldb3	LIM domain binding 3	0.644
Kdr	kinase insert domain protein receptor	0.557
Lepr	leptin receptor	0.519
Grb10	growth factor receptor bound protein 10	0.494	Human
Vegfa	vascular endothelial growth factor A	0.425	Human
Smad6	MAD homolog 6 (Drosophila)	0.375
Egln1	EGL nine homolog 1 (C. elegans)	0.327
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.318
Twist2	twist homolog 2 (Drosophila)	0.283
Epas1	endothelial PAS domain protein 1	0.250	Mouse
Sox17	SRY-box containing gene 17	0.241
Gopc	golgi associated PDZ and coiled-coil motif containing	0.207
Ptprb	protein tyrosine phosphatase, receptor type, B	0.194
Wnt5a	wingless-related MMTV integration site 5A	0.168
Nos3	nitric oxide synthase 3, endothelial cell	0.161
Meox2	mesenchyme homeobox 2	0.156
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.139
Nog	noggin	0.132
Dlg1	discs, large homolog 1 (Drosophila)	0.121
Ece1	endothelin converting enzyme 1	0.118
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.107
Plxnd1	plexin D1	0.093
Acvr1	activin A receptor, type 1	0.093
Vangl2	vang-like 2 (van gogh, Drosophila)	0.089
Gata4	GATA binding protein 4	0.084
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.078
Hes1	hairy and enhancer of split 1 (Drosophila)	0.077
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.073
Arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.072
Plcg1	phospholipase C, gamma 1	0.070
Tbx3	T-box 3	0.069
Efnb2	ephrin B2	0.068
Wt1	Wilms tumor 1 homolog	0.067
Lmx1b	LIM homeobox transcription factor 1 beta	0.067
Pax3	paired box gene 3	0.066
Sox9	SRY-box containing gene 9	0.062
Bmp4	bone morphogenetic protein 4	0.062
Pthlh	parathyroid hormone-like peptide	0.061
Fzd4	frizzled homolog 4 (Drosophila)	0.060
Plcd1	phospholipase C, delta 1	0.060
Tie1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.059
Fgf8	fibroblast growth factor 8	0.057	Mouse
Pax2	paired box gene 2	0.056
Hand2	heart and neural crest derivatives expressed transcript 2	0.055
Sox18	SRY-box containing gene 18	0.052
Ank1	ankyrin 1, erythroid	0.052
Vhl	von Hippel-Lindau tumor suppressor	0.052	Zebrafish
Smad3	MAD homolog 3 (Drosophila)	0.051
Nodal	nodal	0.050
Tbx15	T-box 15	0.049
Shh	sonic hedgehog	0.049	Zebrafish
Flt1	FMS-like tyrosine kinase 1	0.048	Human
Tgfbr3	transforming growth factor, beta receptor III	0.047
Rdh10	retinol dehydrogenase 10 (all-trans)	0.047
Esam	endothelial cell-specific adhesion molecule	0.046
Gata6	GATA binding protein 6	0.046
Tax1bp1	Tax1 (human T-cell leukemia virus type I) binding protein 1	0.046
Col4a3	collagen, type IV, alpha 3	0.046
Stat3	signal transducer and activator of transcription 3	0.045
Plxna1	plexin A1	0.042
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.041
Flt4	FMS-like tyrosine kinase 4	0.040
Kcnj12	potassium inwardly-rectifying channel, subfamily J, member 12	0.040
Fzd8	frizzled homolog 8 (Drosophila)	0.038	Mouse
Ehd2	EH-domain containing 2	0.038
Eng	endoglin	0.038
Chrd	chordin	0.038
Ebf3	early B-cell factor 3	0.037
Npr3	natriuretic peptide receptor 3	0.037
Fbln1	fibulin 1	0.036
Pitx2	paired-like homeodomain transcription factor 2	0.036
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.035
Foxc1	forkhead box C1	0.035
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.035
Large	like-glycosyltransferase	0.034
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.033
Smad7	MAD homolog 7 (Drosophila)	0.033
Prkci	protein kinase C, iota	0.032
Gbx2	gastrulation brain homeobox 2	0.031
Otp	orthopedia homolog (Drosophila)	0.031
Sgcd	sarcoglycan, delta (dystrophin-associated glycoprotein)	0.031
Jag1	jagged 1	0.031
She	src homology 2 domain-containing transforming protein E	0.031
Anxa2	annexin A2	0.030
Tbx1	T-box 1	0.030
Wwc2	WW, C2 and coiled-coil domain containing 2	0.030
Ptch2	patched homolog 2	0.029
Epha4	Eph receptor A4	0.029
Tcf21	transcription factor 21	0.029
Insr	insulin receptor	0.028
Irs1	insulin receptor substrate 1	0.028
Dab1	disabled homolog 1 (Drosophila)	0.028
Cdh15	cadherin 15	0.028
Fli1	Friend leukemia integration 1	0.028
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.027
Cd151	CD151 antigen	0.027
Spry4	sprouty homolog 4 (Drosophila)	0.027
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.026
Tcf15	transcription factor 15	0.026
Ctnnb1	catenin (cadherin associated protein), beta 1	0.026
Notch2	Notch gene homolog 2 (Drosophila)	0.026
Anxa1	annexin A1	0.026
Tspan12	tetraspanin 12	0.025
Nedd4	neural precursor cell expressed, developmentally down-regulated 4	0.025
Rac1	RAS-related C3 botulinum substrate 1	0.025
Pou3f3	POU domain, class 3, transcription factor 3	0.025
Pou3f1	POU domain, class 3, transcription factor 1	0.024
Skor1	SKI family transcriptional corepressor 1	0.024
Cyld	cylindromatosis (turban tumor syndrome)	0.024
Hoxa13	homeobox A13	0.023
Scx	scleraxis	0.023
Foxd3	forkhead box D3	0.023
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.023
Cdh5	cadherin 5	0.023
Ptgfr	prostaglandin F receptor	0.023
Tbx2	T-box 2	0.023
Nsf	N-ethylmaleimide sensitive fusion protein	0.022
Btbd17	BTB (POZ) domain containing 17	0.022
Gli2	GLI-Kruppel family member GLI2	0.022
Sox7	SRY-box containing gene 7	0.022
Cntn2	contactin 2	0.021
Nrk	Nik related kinase	0.021
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.021
Fzd7	frizzled homolog 7 (Drosophila)	0.021	Mouse
Kcnj3	potassium inwardly-rectifying channel, subfamily J, member 3	0.021
Gpc3	glypican 3	0.021
Epor	erythropoietin receptor	0.020
Adra1a	adrenergic receptor, alpha 1a	0.020
Pax7	paired box gene 7	0.020
Ptprg	protein tyrosine phosphatase, receptor type, G	0.020
Lama4	laminin, alpha 4	0.020
Igf1r	insulin-like growth factor I receptor	0.020
Adam17	a disintegrin and metallopeptidase domain 17	0.020
Matn4	matrilin 4	0.020
Fgf15	fibroblast growth factor 15	0.020
Hoxd13	homeobox D13	0.019
Pcdh12	protocadherin 12	0.019
Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.019
Axin2	axin2	0.019
Efna1	ephrin A1	0.019
Prrx1	paired related homeobox 1	0.019
Adra2a	adrenergic receptor, alpha 2a	0.019
Fzd9	frizzled homolog 9 (Drosophila)	0.019	Mouse
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.019
Egfr	epidermal growth factor receptor	0.019
Lmx1a	LIM homeobox transcription factor 1 alpha	0.019
Zfpm2	zinc finger protein, multitype 2	0.018
Emp2	epithelial membrane protein 2	0.018
Plxna2	plexin A2	0.018
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.017
Shc3	src homology 2 domain-containing transforming protein C3	0.017
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.017
Gdf1	growth differentiation factor 1	0.017
Il6st	interleukin 6 signal transducer	0.017
Gli1	GLI-Kruppel family member GLI1	0.017
Wnt1	wingless-related MMTV integration site 1	0.017
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.017
Kcnd3	potassium voltage-gated channel, Shal-related family, member 3	0.017
Dmd	dystrophin, muscular dystrophy	0.016
Onecut1	one cut domain, family member 1	0.016
Hoxd9	homeobox D9	0.016
Cxcl12	chemokine (C-X-C motif) ligand 12	0.016
Tmem64	transmembrane protein 64	0.016
Fgfbp1	fibroblast growth factor binding protein 1	0.016
Bcl2	B-cell leukemia/lymphoma 2	0.016
Igf2	insulin-like growth factor 2	0.016
Lhx1	LIM homeobox protein 1	0.016
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.016
Wnt3a	wingless-related MMTV integration site 3A	0.016
Ptgs2	prostaglandin-endoperoxide synthase 2	0.016
Pdgfb	platelet derived growth factor, B polypeptide	0.016
Socs5	suppressor of cytokine signaling 5	0.016
Cflar	CASP8 and FADD-like apoptosis regulator	0.016
Myod1	myogenic differentiation 1	0.016
Sall3	sal-like 3 (Drosophila)	0.015
Npr2	natriuretic peptide receptor 2	0.015
Rarg	retinoic acid receptor, gamma	0.015
Wnt6	wingless-related MMTV integration site 6	0.015
Dvl1	dishevelled, dsh homolog 1 (Drosophila)	0.015
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.015
Trp63	transformation related protein 63	0.015
Sema3c	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	0.015
Wnt9b	wingless-type MMTV integration site 9B	0.015
Kcnd2	potassium voltage-gated channel, Shal-related family, member 2	0.014
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.014
Wnt11	wingless-related MMTV integration site 11	0.014
Arap3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.014
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.014
Nkd2	naked cuticle 2 homolog (Drosophila)	0.014
Skil	SKI-like	0.014
Pcdh18	protocadherin 18	0.014
Pkdcc	protein kinase domain containing, cytoplasmic	0.014
Wnt9a	wingless-type MMTV integration site 9A	0.014
Efna5	ephrin A5	0.014
Gsc	goosecoid homeobox	0.014
Eya1	eyes absent 1 homolog (Drosophila)	0.014
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.014
Myh10	myosin, heavy polypeptide 10, non-muscle	0.013
Dmc1	DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)	0.013
Pcsk6	proprotein convertase subtilisin/kexin type 6	0.013
Actn2	actinin alpha 2	0.013
Acan	aggrecan	0.013
Nkx2-1	NK2 homeobox 1	0.013
Flii	flightless I homolog (Drosophila)	0.013
Gh	growth hormone	0.013
Krt77	keratin 77	0.013
Gsx1	GS homeobox 1	0.013
Hdac7	histone deacetylase 7	0.013
Rnf11	ring finger protein 11	0.013
Sh3pxd2a	SH3 and PX domains 2A	0.013
Vegfc	vascular endothelial growth factor C	0.013
Oprd1	opioid receptor, delta 1	0.013
Lama5	laminin, alpha 5	0.013
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.013
Spry2	sprouty homolog 2 (Drosophila)	0.013
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.013
Dhh	desert hedgehog	0.013
Ppara	peroxisome proliferator activated receptor alpha	0.012
Neurog3	neurogenin 3	0.012
Cdk14	cyclin-dependent kinase 14	0.012
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.012
Spna1	spectrin alpha 1	0.012
Prkce	protein kinase C, epsilon	0.012	Mouse
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.012
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.012
Nfia	nuclear factor I/A	0.012
Gdnf	glial cell line derived neurotrophic factor	0.012
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.012
Col12a1	collagen, type XII, alpha 1	0.012
Zic3	zinc finger protein of the cerebellum 3	0.012
Mmp16	matrix metallopeptidase 16	0.012
Podxl	podocalyxin-like	0.012
Myoc	myocilin	0.012
Phc2	polyhomeotic-like 2 (Drosophila)	0.012
Rarb	retinoic acid receptor, beta	0.012
Nrap	nebulin-related anchoring protein	0.012
Ntn1	netrin 1	0.012
Prdx6	peroxiredoxin 6	0.012
Adcy9	adenylate cyclase 9	0.012
Mrc2	mannose receptor, C type 2	0.012
Wbp1	WW domain binding protein 1	0.012
Ednra	endothelin receptor type A	0.012
Ptk2	PTK2 protein tyrosine kinase 2	0.012
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.012
Edn3	endothelin 3	0.012
Atp1b2	ATPase, Na+/K+ transporting, beta 2 polypeptide	0.012
Musk	muscle, skeletal, receptor tyrosine kinase	0.012
Gabra1	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1	0.011
App	amyloid beta (A4) precursor protein	0.011
Homer2	homer homolog 2 (Drosophila)	0.011
Nphs2	nephrosis 2 homolog, podocin (human)	0.011
Sall1	sal-like 1 (Drosophila)	0.011
Zfp185	zinc finger protein 185	0.011
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.011
Sgcg	sarcoglycan, gamma (dystrophin-associated glycoprotein)	0.011
Gfra2	glial cell line derived neurotrophic factor family receptor alpha 2	0.011
Srpk3	serine/arginine-rich protein specific kinase 3	0.011
Parva	parvin, alpha	0.011
Wnt3	wingless-related MMTV integration site 3	0.011
Sall4	sal-like 4 (Drosophila)	0.011
Hoxd8	homeobox D8	0.011
Fign	fidgetin	0.011
Klf7	Kruppel-like factor 7 (ubiquitous)	0.011
Sox1	SRY-box containing gene 1	0.011
Srpx	sushi-repeat-containing protein	0.011
Apoe	apolipoprotein E	0.011
Ednrb	endothelin receptor type B	0.011
Plin4	perilipin 4	0.011
Notch1	Notch gene homolog 1 (Drosophila)	0.011
Cacna1g	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.011
Kcne1l	potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene	0.011
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.011
Ptpn12	protein tyrosine phosphatase, non-receptor type 12	0.011
Ptk7	PTK7 protein tyrosine kinase 7	0.011
Atoh7	atonal homolog 7 (Drosophila)	0.011
Hoxd4	homeobox D4	0.011
Dlg2	discs, large homolog 2 (Drosophila)	0.011
Arhgap1	Rho GTPase activating protein 1	0.011
Bmp5	bone morphogenetic protein 5	0.011
Cntn4	contactin 4	0.011
Lrp2	low density lipoprotein receptor-related protein 2	0.011
Robo4	roundabout homolog 4 (Drosophila)	0.011
Nrp1	neuropilin 1	0.011	Zebrafish
BC057022	cDNA sequence BC057022	0.010
Ptger1	prostaglandin E receptor 1 (subtype EP1)	0.010
Elk3	ELK3, member of ETS oncogene family	0.010
Dpysl2	dihydropyrimidinase-like 2	0.010
Kcnk3	potassium channel, subfamily K, member 3	0.010
Wnt7b	wingless-related MMTV integration site 7B	0.010
Tek	endothelial-specific receptor tyrosine kinase	0.010
Tspan9	tetraspanin 9	0.010
Bcl6b	B-cell CLL/lymphoma 6, member B	0.010
Foxa2	forkhead box A2	0.010
Hoxa7	homeobox A7	0.010
Arhgef7	Rho guanine nucleotide exchange factor (GEF7)	0.010
Klf3	Kruppel-like factor 3 (basic)	0.010
Nfib	nuclear factor I/B	0.010
Chrna7	cholinergic receptor, nicotinic, alpha polypeptide 7	0.010
Col22a1	collagen, type XXII, alpha 1	0.010
Mark1	MAP/microtubule affinity-regulating kinase 1	0.010
Acvrl1	activin A receptor, type II-like 1	0.010
Fgd5	FYVE, RhoGEF and PH domain containing 5	0.010
Syt7	synaptotagmin VII	0.010