Mus musculus

89 known processes

Rspo2

R-spondin 2 homolog (Xenopus laevis)

(Aliases: AA673245,2610028F08Rik,D430027K22,ftls)

Rspo2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.998
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.997
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 0.995
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.994
cell proliferation in hindbrain GO:0021534 10 0.993
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.991
tendon formation GO:0035992 4 0.989
mesenchymal cell apoptotic process involved in nephron morphogenesis GO:1901145 4 0.989
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.986
embryonic skeletal system morphogenesis GO:0048704 91 0.982
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.981
embryonic organ morphogenesis GO:0048562 276 0.979
embryonic skeletal system development GO:0048706 120 0.977
regionalization GO:0003002 337 0.976
skeletal system development GO:0001501 356 0.974
embryonic heart tube formation GO:0003144 1 0.971
auditory receptor cell fate determination GO:0042668 3 0.966
negative regulation of cell development GO:0010721 169 0.966
regulation of glial cell differentiation GO:0045685 41 0.966
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.964
negative regulation of stem cell maintenance GO:1902455 4 0.956
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.952
regulation of astrocyte differentiation GO:0048710 20 0.951
chondrocyte differentiation GO:0002062 72 0.947
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.943
skeletal system morphogenesis GO:0048705 203 0.942
roof plate formation GO:0021509 1 0.937
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.933
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.932
commitment of multipotent stem cells to neuronal lineage in forebrain GO:0021898 3 0.927
semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:0071527 1 0.926
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.924
ear morphogenesis GO:0042471 118 0.920
cerebral cortex gabaergic interneuron fate commitment GO:0021893 2 0.913
myeloid cell differentiation GO:0030099 233 0.906
medulla oblongata development GO:0021550 3 0.898
branching morphogenesis of an epithelial tube GO:0048754 159 0.897
embryonic skeletal joint morphogenesis GO:0060272 11 0.895
cerebral cortex gabaergic interneuron differentiation GO:0021892 9 0.891
regulation of chondrocyte differentiation GO:0032330 33 0.883
bone development GO:0060348 120 0.881
floor plate morphogenesis GO:0033505 3 0.879
odontogenesis GO:0042476 78 0.876
gliogenesis GO:0042063 141 0.857
hindbrain tangential cell migration GO:0021934 2 0.854
axial mesodermal cell fate commitment GO:0048322 1 0.848
trachea formation GO:0060440 3 0.845
locus ceruleus development GO:0021703 1 0.842
regulation of cartilage development GO:0061035 44 0.840
tendon cell differentiation GO:0035990 4 0.838
cell proliferation in external granule layer GO:0021924 10 0.837
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.835
limb morphogenesis GO:0035108 149 0.834
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.833
cerebellar granule cell precursor proliferation GO:0021930 10 0.831
regulation of transcription from rna polymerase ii promoter involved in forebrain neuron fate commitment GO:0021882 3 0.822
epiblast cell extraembryonic ectoderm cell signaling involved in anterior posterior axis specification GO:0060802 1 0.819
regulation of system process GO:0044057 200 0.818
embryonic camera type eye development GO:0031076 36 0.815
negative regulation of endodermal cell differentiation GO:1903225 1 0.814
negative regulation of gastrulation GO:2000542 3 0.807
metanephric nephron tubule formation GO:0072289 4 0.801
axis elongation involved in somitogenesis GO:0090245 4 0.799
appendage development GO:0048736 166 0.797
amine metabolic process GO:0009308 45 0.794
neuron projection guidance GO:0097485 141 0.786
erythrocyte differentiation GO:0030218 88 0.781
telencephalon development GO:0021537 186 0.780
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.780
limb development GO:0060173 166 0.777
regulation of stem cell maintenance GO:2000036 17 0.775
cloacal septation GO:0060197 2 0.773
response to organic cyclic compound GO:0014070 198 0.772
positive regulation of cell development GO:0010720 237 0.772
embryonic skeletal joint development GO:0072498 13 0.767
endodermal cell fate specification GO:0001714 4 0.765
pyramidal neuron migration GO:0021852 1 0.761
neural tube closure GO:0001843 90 0.760
sensory organ morphogenesis GO:0090596 242 0.760
hippocampus development GO:0021766 52 0.759
hindbrain development GO:0030902 128 0.758
muscle cell development GO:0055001 133 0.737
negative regulation of neuron differentiation GO:0045665 101 0.736
inflammatory response GO:0006954 244 0.735
epithelial cell development GO:0002064 159 0.735
striated muscle cell development GO:0055002 125 0.725
negative regulation of prostatic bud formation GO:0060686 4 0.720
chondrocyte development GO:0002063 24 0.718
positive regulation of tendon cell differentiation GO:2001051 1 0.714
positive regulation of nervous system development GO:0051962 221 0.713
pancreatic pp cell fate commitment GO:0003329 2 0.712
regulation of cellular amine metabolic process GO:0033238 20 0.708
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.706
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.705
epithelial tube morphogenesis GO:0060562 303 0.703
cerebral cortex neuron differentiation GO:0021895 19 0.697
epidermis development GO:0008544 187 0.694
regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256 2 0.689
telencephalon regionalization GO:0021978 14 0.689
myeloid leukocyte differentiation GO:0002573 119 0.685
cartilage development GO:0051216 140 0.684
intracellular distribution of mitochondria GO:0048312 1 0.680
embryonic viscerocranium morphogenesis GO:0048703 8 0.679
cellular ketone metabolic process GO:0042180 84 0.677
central nervous system neuron differentiation GO:0021953 162 0.677
mesonephric tubule development GO:0072164 94 0.667
cardiac chamber morphogenesis GO:0003206 93 0.660
gastrulation GO:0007369 116 0.658
cellular amino acid metabolic process GO:0006520 103 0.656
regulation of smoothened signaling pathway GO:0008589 58 0.653
positive regulation of neuron differentiation GO:0045666 141 0.651
mesenchymal cell differentiation GO:0048762 107 0.648
astrocyte fate commitment GO:0060018 4 0.641
noradrenergic neuron differentiation GO:0003357 6 0.638
positive regulation of glial cell differentiation GO:0045687 21 0.636
glial cell differentiation GO:0010001 131 0.635
ossification GO:0001503 216 0.630
maternal process involved in parturition GO:0060137 1 0.629
mesenchyme development GO:0060485 152 0.619
trophectodermal cellular morphogenesis GO:0001831 3 0.617
bone morphogenesis GO:0060349 78 0.612
neural tube formation GO:0001841 108 0.606
regulation of neuron projection development GO:0010975 169 0.603
axonogenesis GO:0007409 274 0.600
smoothened signaling pathway involved in dorsal ventral neural tube patterning GO:0060831 12 0.597
endochondral bone morphogenesis GO:0060350 50 0.593
positive regulation of neuron projection regeneration GO:0070572 2 0.591
oligodendrocyte differentiation GO:0048709 53 0.588
forebrain neuron fate commitment GO:0021877 13 0.586
ureteric bud development GO:0001657 94 0.586
cd4 positive alpha beta t cell differentiation GO:0043367 41 0.585
regulation of neuron differentiation GO:0045664 281 0.584
forebrain generation of neurons GO:0021872 63 0.577
cellular amine metabolic process GO:0044106 44 0.576
brain morphogenesis GO:0048854 32 0.575
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.575
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus GO:1901522 7 0.573
oligodendrocyte development GO:0014003 20 0.573
otic placode formation GO:0043049 1 0.572
positive regulation of dna templated transcription elongation GO:0032786 2 0.571
regulation of response to wounding GO:1903034 189 0.566
subpallium development GO:0021544 20 0.559
apoptotic process involved in outflow tract morphogenesis GO:0003275 2 0.556
positive regulation of odontogenesis GO:0042482 4 0.552
regulation of cellular ketone metabolic process GO:0010565 66 0.550
regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 0.541
neural tube patterning GO:0021532 43 0.539
prostate gland morphogenesis GO:0060512 32 0.535
bmp signaling pathway involved in heart development GO:0061312 2 0.534
corticotropin hormone secreting cell differentiation GO:0060128 3 0.530
substrate independent telencephalic tangential migration GO:0021826 8 0.528
axon guidance GO:0007411 141 0.523
negative regulation of chondrocyte differentiation GO:0032331 13 0.519
axial mesoderm formation GO:0048320 3 0.511
cartilage morphogenesis GO:0060536 11 0.508
connective tissue development GO:0061448 179 0.507
positive regulation of cellular amine metabolic process GO:0033240 5 0.507
pancreatic pp cell differentiation GO:0003312 2 0.505
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.503
positive regulation of wnt signaling pathway GO:0030177 45 0.502
negative regulation of mesodermal cell fate specification GO:0042662 3 0.502
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.501
positive regulation of stress activated mapk cascade GO:0032874 48 0.499
regulation of transcription involved in primary germ layer cell fate commitment GO:0060796 2 0.497
neural crest cell fate commitment GO:0014034 1 0.496
cerebellum development GO:0021549 77 0.495
subpallium neuron fate commitment GO:0060163 2 0.492
response to growth factor GO:0070848 198 0.490
dorsal ventral neural tube patterning GO:0021904 28 0.489
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.486
forebrain radial glial cell differentiation GO:0021861 4 0.480
transforming growth factor beta receptor signaling pathway involved in primitive streak formation GO:0090010 1 0.478
ventricular cardiac muscle cell differentiation GO:0055012 17 0.473
metanephric capsule specification GO:0072267 1 0.471
cellular homeostasis GO:0019725 240 0.470
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.470
closure of optic fissure GO:0061386 2 0.469
cardiac right ventricle formation GO:0003219 3 0.469
regulation of intracellular transport GO:0032386 159 0.464
regulation of gliogenesis GO:0014013 50 0.461
ear development GO:0043583 200 0.458
negative regulation of cell fate specification GO:0009996 4 0.457
regulation of organ morphogenesis GO:2000027 144 0.455
epithelial to mesenchymal transition GO:0001837 47 0.454
astrocyte differentiation GO:0048708 43 0.453
regulation of cellular amino acid metabolic process GO:0006521 5 0.453
lymphocyte differentiation GO:0030098 242 0.451
myeloid cell homeostasis GO:0002262 114 0.451
epithelial tube formation GO:0072175 130 0.448
somitogenesis GO:0001756 69 0.447
cellular chemical homeostasis GO:0055082 215 0.444
embryonic appendage morphogenesis GO:0035113 126 0.443
regulation of fat cell differentiation GO:0045598 81 0.442
regulation of mast cell differentiation GO:0060375 3 0.439
camera type eye development GO:0043010 266 0.436
branching involved in prostate gland morphogenesis GO:0060442 15 0.432
pituitary gland development GO:0021983 38 0.432
primary neural tube formation GO:0014020 95 0.432
cellular component assembly involved in morphogenesis GO:0010927 139 0.428
homeostasis of number of cells GO:0048872 210 0.427
negative regulation of glial cell proliferation GO:0060253 4 0.427
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.426
regulation of epithelial to mesenchymal transition GO:0010717 22 0.425
positive regulation of cell motility GO:2000147 116 0.420
leukocyte differentiation GO:0002521 342 0.416
negative regulation of epithelial cell proliferation GO:0050680 64 0.413
stem cell differentiation GO:0048863 268 0.413
noradrenergic neuron development GO:0003358 3 0.409
mechanoreceptor differentiation GO:0042490 67 0.406
specification of organ position GO:0010159 3 0.403
negative regulation of astrocyte differentiation GO:0048712 10 0.399
tube formation GO:0035148 140 0.398
ventricular zone neuroblast division GO:0021847 3 0.395
positive regulation of apoptotic process GO:0043065 217 0.395
axial mesodermal cell fate specification GO:0048327 1 0.393
positive regulation of cartilage development GO:0061036 18 0.393
negative regulation of synapse maturation GO:2000297 2 0.392
positive regulation of epithelial cell proliferation GO:0050679 68 0.391
primitive streak formation GO:0090009 10 0.390
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.389
regulation of cell cycle GO:0051726 281 0.387
positive regulation of stem cell proliferation GO:2000648 59 0.386
canonical wnt signaling pathway GO:0060070 130 0.385
muscle fiber development GO:0048747 76 0.378
pigmentation GO:0043473 71 0.374
t cell activation GO:0042110 289 0.374
mesonephros development GO:0001823 97 0.373
embryonic limb morphogenesis GO:0030326 126 0.365
hematopoietic progenitor cell differentiation GO:0002244 143 0.364
positive regulation of programmed cell death GO:0043068 218 0.364
regulation of muscle tissue development GO:1901861 97 0.362
negative regulation of smoothened signaling pathway GO:0045879 25 0.360
striated muscle tissue development GO:0014706 293 0.357
positive regulation of branching involved in lung morphogenesis GO:0061047 4 0.357
membrane organization GO:0061024 245 0.356
negative regulation of apoptotic process involved in outflow tract morphogenesis GO:1902257 2 0.355
regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000148 1 0.350
oculomotor nerve morphogenesis GO:0021622 2 0.349
hemangioblast cell differentiation GO:0060217 1 0.348
branching involved in ureteric bud morphogenesis GO:0001658 56 0.347
forebrain neuron differentiation GO:0021879 52 0.347
developmental maturation GO:0021700 193 0.344
regulation of stress activated mapk cascade GO:0032872 69 0.342
cellular response to oxidative stress GO:0034599 76 0.342
adenohypophysis development GO:0021984 14 0.338
multicellular organismal homeostasis GO:0048871 164 0.337
spinal cord association neuron differentiation GO:0021527 14 0.337
globus pallidus development GO:0021759 2 0.335
digestive system development GO:0055123 200 0.335
muscle cell differentiation GO:0042692 261 0.332
regulation of endodermal cell fate specification GO:0042663 2 0.332
circadian rhythm GO:0007623 114 0.331
cardiac muscle cell development GO:0055013 39 0.329
mesonephric epithelium development GO:0072163 94 0.327
regulation of auditory receptor cell differentiation GO:0045607 4 0.325
axial mesodermal cell differentiation GO:0048321 1 0.323
primary prostatic bud elongation GO:0060516 2 0.321
fat cell differentiation GO:0045444 160 0.319
spermatogenesis GO:0007283 284 0.319
positive regulation of oligodendrocyte differentiation GO:0048714 9 0.318
cognition GO:0050890 149 0.318
b cell differentiation GO:0030183 78 0.317
lipid biosynthetic process GO:0008610 179 0.316
t cell differentiation GO:0030217 174 0.316
appendage morphogenesis GO:0035107 149 0.313
embryonic eye morphogenesis GO:0048048 29 0.312
wnt signaling pathway involved in somitogenesis GO:0090244 4 0.312
cerebral cortex gabaergic interneuron migration GO:0021853 6 0.310
regulation of neuron maturation GO:0014041 5 0.309
skeletal muscle cell differentiation GO:0035914 66 0.308
positive regulation of mesenchymal cell apoptotic process GO:2001055 3 0.308
organelle assembly GO:0070925 177 0.307
positive regulation of cell death GO:0010942 224 0.307
ureter morphogenesis GO:0072197 4 0.306
cerebellar cortex development GO:0021695 48 0.304
embryonic placenta development GO:0001892 98 0.301
Mouse
divalent metal ion transport GO:0070838 172 0.298
organic hydroxy compound biosynthetic process GO:1901617 77 0.296
embryonic heart tube anterior posterior pattern specification GO:0035054 3 0.296
g protein coupled receptor signaling pathway GO:0007186 243 0.295
erythrocyte maturation GO:0043249 6 0.294
organonitrogen compound biosynthetic process GO:1901566 192 0.294
muscle cell proliferation GO:0033002 52 0.294
apoptotic signaling pathway GO:0097190 306 0.293
midgut development GO:0007494 4 0.292
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.290
negative regulation of apoptotic process involved in morphogenesis GO:1902338 6 0.289
lung development GO:0030324 164 0.286
actin cytoskeleton organization GO:0030036 220 0.284
limbic system development GO:0021761 72 0.283
cardiac muscle tissue development GO:0048738 130 0.282
mesenchymal cell proliferation GO:0010463 44 0.282
regulation of retina development in camera type eye GO:1902866 3 0.281
pallium development GO:0021543 120 0.279
hair follicle development GO:0001942 85 0.277
cranial nerve formation GO:0021603 4 0.277
positive regulation of ossification GO:0045778 47 0.277
cardiogenic plate morphogenesis GO:0003142 1 0.276
regulation of myoblast differentiation GO:0045661 29 0.275
anatomical structure homeostasis GO:0060249 145 0.274
phenol containing compound biosynthetic process GO:0046189 21 0.272
negative regulation of gliogenesis GO:0014014 23 0.272
muscle tissue development GO:0060537 308 0.271
melanocyte differentiation GO:0030318 25 0.270
bmp signaling pathway GO:0030509 93 0.270
cellular response to cytokine stimulus GO:0071345 189 0.270
inner ear morphogenesis GO:0042472 101 0.268
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 18 0.267
regulation of oligodendrocyte differentiation GO:0048713 23 0.266
urogenital system development GO:0001655 261 0.266
negative regulation of glial cell differentiation GO:0045686 21 0.265
mitral valve development GO:0003174 4 0.264
heart field specification GO:0003128 6 0.264
metencephalon development GO:0022037 89 0.264
positive regulation of hh target transcription factor activity GO:0007228 3 0.263
osteoblast development GO:0002076 17 0.263
cellular response to growth factor stimulus GO:0071363 197 0.262
embryonic neurocranium morphogenesis GO:0048702 3 0.262
stem cell proliferation GO:0072089 117 0.260
odontogenesis of dentin containing tooth GO:0042475 66 0.259
regulation of kinase activity GO:0043549 249 0.258
embryonic process involved in female pregnancy GO:0060136 7 0.258
embryonic nail plate morphogenesis GO:0035880 3 0.257
renal vesicle induction GO:0072034 3 0.255
oocyte differentiation GO:0009994 35 0.255
leukocyte chemotaxis GO:0030595 69 0.255
positive regulation of semaphorin plexin signaling pathway GO:2001262 1 0.255
positive regulation of keratinocyte proliferation GO:0010838 4 0.254
forebrain neuron development GO:0021884 30 0.254
posttranscriptional regulation of gene expression GO:0010608 155 0.250
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.250
columnar cuboidal epithelial cell development GO:0002066 29 0.248
positive regulation of gliogenesis GO:0014015 27 0.247
growth plate cartilage chondrocyte growth GO:0003430 2 0.245
neural tube development GO:0021915 160 0.244
negative regulation of alcohol biosynthetic process GO:1902931 4 0.244
positive regulation of transcription via serum response element binding GO:0010735 1 0.243
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.243
frontal suture morphogenesis GO:0060364 2 0.240
positive regulation of chondrocyte differentiation GO:0032332 13 0.240
positive regulation of canonical wnt signaling pathway GO:0090263 29 0.239
regulation of transcription from rna polymerase ii promoter involved in ventral spinal cord interneuron specification GO:0021913 4 0.239
regulation of bmp signaling pathway GO:0030510 60 0.238
negative regulation of kidney development GO:0090185 15 0.236
pancreatic a cell fate commitment GO:0003326 2 0.233
spinal cord development GO:0021510 81 0.233
carbohydrate homeostasis GO:0033500 128 0.233
ameboidal type cell migration GO:0001667 128 0.231
activation of meiosis GO:0090427 4 0.230
regulation of cellular response to stress GO:0080135 159 0.230
digestive tract morphogenesis GO:0048546 147 0.230
negative regulation of cell cycle GO:0045786 123 0.229
cardiac epithelial to mesenchymal transition GO:0060317 18 0.228
regulation of osteoblast differentiation GO:0045667 67 0.228
stem cell development GO:0048864 219 0.228
spinal cord motor neuron differentiation GO:0021522 35 0.228
regulation of epidermal cell differentiation GO:0045604 21 0.227
hindbrain morphogenesis GO:0021575 46 0.227
hypophysis morphogenesis GO:0048850 3 0.227
digestive tract development GO:0048565 190 0.225
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.225
germ cell development GO:0007281 185 0.224
ventricular cardiac myofibril assembly GO:0055005 3 0.222
regulation of secretion GO:0051046 274 0.222
anatomical structure maturation GO:0071695 49 0.222
skeletal muscle organ development GO:0060538 163 0.222
anterior commissure morphogenesis GO:0021960 6 0.220
negative regulation of immune system process GO:0002683 209 0.219
regulation of cytokine production GO:0001817 266 0.219
positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0072108 3 0.219
axonogenesis involved in innervation GO:0060385 5 0.218
regulation of protein stability GO:0031647 52 0.218
heart contraction GO:0060047 93 0.218
lens epithelial cell proliferation GO:0097166 1 0.217
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.217
mesenchymal cell differentiation involved in renal system development GO:2001012 6 0.215
specification of organ identity GO:0010092 30 0.213
eye photoreceptor cell development GO:0042462 31 0.213
inner cell mass cellular morphogenesis GO:0001828 1 0.213
cell chemotaxis GO:0060326 81 0.213
respiratory gaseous exchange GO:0007585 43 0.211
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis GO:2000166 1 0.211
respiratory system development GO:0060541 190 0.209
negative regulation of branching involved in ureteric bud morphogenesis GO:0090191 4 0.209
regulation of epithelial cell proliferation GO:0050678 141 0.207
mesoderm development GO:0007498 100 0.207
response to inorganic substance GO:0010035 96 0.207
inner ear receptor cell differentiation GO:0060113 61 0.206
response to bmp GO:0071772 14 0.204
gabaergic neuron differentiation GO:0097154 11 0.204
stem cell maintenance GO:0019827 130 0.204
eye photoreceptor cell differentiation GO:0001754 41 0.203
positive regulation of cerebellar granule cell precursor proliferation GO:0021940 10 0.202
forebrain morphogenesis GO:0048853 17 0.202
regulation of heart morphogenesis GO:2000826 22 0.201
palate development GO:0060021 76 0.201
regulation of heart contraction GO:0008016 77 0.200
learning GO:0007612 98 0.200
response to organonitrogen compound GO:0010243 246 0.199
negative regulation of response to wounding GO:1903035 77 0.198
cranial suture morphogenesis GO:0060363 8 0.198
semicircular canal formation GO:0060876 1 0.197
cytokine production GO:0001816 319 0.197
gland development GO:0048732 330 0.195
forebrain cell migration GO:0021885 58 0.194
peripheral nervous system neuron axonogenesis GO:0048936 3 0.194
diencephalon development GO:0021536 63 0.193
histone acetylation GO:0016573 41 0.193
spinal cord oligodendrocyte cell fate specification GO:0021530 3 0.193
catagen GO:0042637 5 0.192
positive regulation of semaphorin plexin signaling pathway involved in outflow tract morphogenesis GO:2000764 1 0.192
regulation of tendon cell differentiation GO:2001049 1 0.191
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.190
regulation of cell migration GO:0030334 219 0.189
negative regulation of photoreceptor cell differentiation GO:0046533 4 0.189
regulation of skeletal muscle fiber development GO:0048742 36 0.189
neural crest formation GO:0014029 2 0.188
regulation of cardiac muscle cell differentiation GO:2000725 9 0.188
cell type specific apoptotic process GO:0097285 268 0.187
central nervous system neuron axonogenesis GO:0021955 28 0.187
synaptic transmission GO:0007268 329 0.186
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.185
regulation of blood circulation GO:1903522 93 0.185
regulation of endodermal cell differentiation GO:1903224 2 0.185
morphogenesis of a branching epithelium GO:0061138 193 0.185
cerebellum morphogenesis GO:0021587 42 0.184
mesenchymal cell development GO:0014031 93 0.183
nuclear division GO:0000280 158 0.183
Mouse
nephric duct formation GO:0072179 4 0.182
regulation of ion transport GO:0043269 215 0.182
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.180
metanephric dct cell differentiation GO:0072240 3 0.180
regulation of organelle organization GO:0033043 289 0.179
negative regulation of myoblast differentiation GO:0045662 18 0.178
negative regulation of epidermis development GO:0045683 9 0.178
single organismal cell cell adhesion GO:0016337 131 0.177
negative regulation of cardiac chamber morphogenesis GO:1901220 2 0.176
endodermal cell fate commitment GO:0001711 12 0.176
cellular response to organonitrogen compound GO:0071417 145 0.176
negative regulation of nervous system development GO:0051961 156 0.176
mesenchymal cell proliferation involved in ureteric bud development GO:0072138 3 0.176
positive regulation of response to wounding GO:1903036 66 0.176
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.176
cell cell signaling involved in mammary gland development GO:0060764 2 0.174
negative regulation of insulin like growth factor receptor signaling pathway GO:0043569 5 0.173
regulation of neural precursor cell proliferation GO:2000177 70 0.173
organic hydroxy compound metabolic process GO:1901615 203 0.173
notch signaling pathway GO:0007219 71 0.172
left lung development GO:0060459 4 0.171
regulation of kidney development GO:0090183 40 0.169
forebrain regionalization GO:0021871 25 0.168
negative regulation of cartilage development GO:0061037 17 0.167
cell division GO:0051301 120 0.167
optic nerve formation GO:0021634 1 0.166
regulation of myotube differentiation GO:0010830 62 0.166
internal protein amino acid acetylation GO:0006475 42 0.165
auditory receptor cell fate specification GO:0042667 1 0.165
cerebral cortex radial glia guided migration GO:0021801 17 0.165
dendrite development GO:0016358 115 0.164
trachea development GO:0060438 18 0.164
regulation of anatomical structure size GO:0090066 178 0.163
regulation of mesonephros development GO:0061217 24 0.162
carbon catabolite repression of transcription GO:0045013 1 0.162
negative regulation of endodermal cell fate specification GO:0042664 1 0.161
positive regulation of alpha beta t cell differentiation GO:0046638 28 0.161
regulation of stem cell differentiation GO:2000736 50 0.160
blood circulation GO:0008015 195 0.159
spinal cord dorsal ventral patterning GO:0021513 23 0.159
renal capsule formation GO:0072129 1 0.158
spinal cord motor neuron cell fate specification GO:0021520 13 0.157
cellular response to lipid GO:0071396 145 0.157
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.156
ventricular cardiac muscle cell development GO:0055015 11 0.156
ascending aorta morphogenesis GO:0035910 3 0.156
small gtpase mediated signal transduction GO:0007264 97 0.155
regulation of protein kinase activity GO:0045859 232 0.154
chemotaxis GO:0006935 247 0.153
cardiac cell fate specification GO:0060912 2 0.153
nephrogenic mesenchyme morphogenesis GO:0072134 2 0.153
neuron projection extension GO:1990138 64 0.153
negative regulation of keratinocyte differentiation GO:0045617 4 0.152
negative regulation of organelle organization GO:0010639 90 0.151
regulation of hair cycle GO:0042634 11 0.151
mammary placode formation GO:0060596 4 0.150
regulation of nephron tubule epithelial cell differentiation GO:0072182 9 0.150
nephron morphogenesis GO:0072028 69 0.150
ventral spinal cord interneuron specification GO:0021521 11 0.150
positive regulation of cell cycle GO:0045787 92 0.150
regulation of cardiac muscle tissue development GO:0055024 31 0.149
regulation of odontogenesis GO:0042481 18 0.148
regulation of wound healing GO:0061041 40 0.148
regulation of inflammatory response GO:0050727 147 0.148
olfactory lobe development GO:0021988 32 0.147
positive regulation of skeletal muscle tissue regeneration GO:0043415 4 0.147
nephron tubule morphogenesis GO:0072078 68 0.147
oxidation reduction process GO:0055114 342 0.146
oogenesis GO:0048477 56 0.145

Rspo2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.156
musculoskeletal system disease DOID:17 0 0.156