Mus musculus

124 known processes

Alx1

ALX homeobox 1

(Aliases: Cart1,C130005I02,AI314867)

Alx1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
retinal bipolar neuron differentiation GO:0060040 5 0.999
Mouse
neural crest cell migration involved in autonomic nervous system development GO:1901166 5 0.950
skeletal system development GO:0001501 356 0.939
embryonic olfactory bulb interneuron precursor migration GO:0021831 2 0.925
Mouse
globus pallidus development GO:0021759 2 0.899
Mouse
nodal signaling pathway involved in determination of left right asymmetry GO:0038107 2 0.873
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 2 0.849
regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072039 4 0.832
nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry GO:1900164 2 0.831
appendage morphogenesis GO:0035107 149 0.813
embryonic skeletal system morphogenesis GO:0048704 91 0.812
carbon catabolite repression of transcription from rna polymerase ii promoter GO:0000437 1 0.803
skeletal system morphogenesis GO:0048705 203 0.778
negative regulation of cardiac chamber morphogenesis GO:1901220 2 0.774
olfactory lobe development GO:0021988 32 0.762
Mouse
positive regulation of secondary heart field cardioblast proliferation GO:0072513 4 0.754
tendon formation GO:0035992 4 0.743
mammary placode formation GO:0060596 4 0.730
central nervous system neuron differentiation GO:0021953 162 0.723
Mouse
otic placode formation GO:0043049 1 0.710
mesenchymal cell proliferation involved in ureter development GO:0072198 4 0.702
positive regulation of transcription from rna polymerase ii promoter involved in myocardial precursor cell differentiation GO:0003257 3 0.701
limb development GO:0060173 166 0.689
mesenchymal cell apoptotic process involved in nephron morphogenesis GO:1901145 4 0.686
regulation of mesenchymal cell proliferation involved in ureter development GO:0072199 3 0.676
embryonic skeletal system development GO:0048706 120 0.672
neural tube formation GO:0001841 108 0.668
blastocyst development GO:0001824 80 0.666
appendage development GO:0048736 166 0.662
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.656
forebrain neuron development GO:0021884 30 0.643
Mouse
sinoatrial node cell differentiation GO:0060921 3 0.642
primary neural tube formation GO:0014020 95 0.634
renal system development GO:0072001 225 0.620
neural tube closure GO:0001843 90 0.618
axial mesodermal cell fate commitment GO:0048322 1 0.616
regionalization GO:0003002 337 0.614
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 4 0.600
embryonic limb morphogenesis GO:0030326 126 0.595
commitment of neuronal cell to specific neuron type in forebrain GO:0021902 7 0.580
endodermal cell fate commitment GO:0001711 12 0.556
forelimb morphogenesis GO:0035136 40 0.543
Mouse
cerebral cortex tangential migration GO:0021800 7 0.534
Mouse
trophectodermal cell differentiation GO:0001829 21 0.533
embryonic organ morphogenesis GO:0048562 276 0.529
ear development GO:0043583 200 0.528
smoothened signaling pathway involved in dorsal ventral neural tube patterning GO:0060831 12 0.521
stem cell development GO:0048864 219 0.516
embryonic skeletal joint morphogenesis GO:0060272 11 0.506
positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus GO:1901522 7 0.490
neural crest formation GO:0014029 2 0.484
camera type eye development GO:0043010 266 0.483
Mouse
sensory organ morphogenesis GO:0090596 242 0.481
Mouse
epithelial tube morphogenesis GO:0060562 303 0.476
negative regulation of cell fate specification GO:0009996 4 0.454
pyramidal neuron migration GO:0021852 1 0.451
regulation of tongue muscle cell differentiation GO:2001035 2 0.451
negative regulation of canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060829 1 0.447
floor plate morphogenesis GO:0033505 3 0.446
apoptotic process involved in outflow tract morphogenesis GO:0003275 2 0.446
cell fate commitment GO:0045165 210 0.443
Mouse Worm
gastrulation GO:0007369 116 0.439
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 9 0.436
auditory receptor cell fate determination GO:0042668 3 0.435
forebrain generation of neurons GO:0021872 63 0.435
Mouse
specification of organ position GO:0010159 3 0.434
cell proliferation in forebrain GO:0021846 30 0.429
Mouse
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.426
positive regulation of mesenchymal cell proliferation involved in ureter development GO:2000729 3 0.426
spermatogenesis GO:0007283 284 0.425
stem cell maintenance GO:0019827 130 0.424
regulation of transcription involved in primary germ layer cell fate commitment GO:0060796 2 0.423
metanephric capsule specification GO:0072267 1 0.420
axonogenesis GO:0007409 274 0.418
Mouse
embryonic forelimb morphogenesis GO:0035115 32 0.418
Mouse
tube formation GO:0035148 140 0.408
atrioventricular bundle cell differentiation GO:0003167 1 0.400
forebrain neuron fate commitment GO:0021877 13 0.398
cell differentiation in spinal cord GO:0021515 53 0.396
mesonephros development GO:0001823 97 0.396
trophectodermal cellular morphogenesis GO:0001831 3 0.394
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.392
embryonic epithelial tube formation GO:0001838 130 0.391
positive regulation of transcription from rna polymerase ii promoter involved in norepinephrine biosynthetic process GO:2000763 1 0.371
positive regulation of tongue muscle cell differentiation GO:2001037 2 0.369
mesenchyme development GO:0060485 152 0.359
cerebral cortex gabaergic interneuron migration GO:0021853 6 0.355
Mouse
bmp signaling pathway GO:0030509 93 0.353
lung development GO:0030324 164 0.351
oculomotor nerve morphogenesis GO:0021622 2 0.350
embryonic appendage morphogenesis GO:0035113 126 0.349
lipid digestion GO:0044241 7 0.347
Mouse
mesonephric tubule development GO:0072164 94 0.346
kidney epithelium development GO:0072073 121 0.346
neuron projection guidance GO:0097485 141 0.344
Mouse
forebrain neuron differentiation GO:0021879 52 0.343
Mouse
retina morphogenesis in camera type eye GO:0060042 45 0.339
Mouse
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000802 1 0.337
limb morphogenesis GO:0035108 149 0.337
positive regulation of skeletal muscle cell differentiation GO:2001016 4 0.335
mesenchymal cell proliferation GO:0010463 44 0.335
negative regulation of cell development GO:0010721 169 0.326
regulation of skeletal muscle fiber differentiation GO:1902809 3 0.324
epithelial tube formation GO:0072175 130 0.324
embryonic digit morphogenesis GO:0042733 56 0.323
Mouse
positive regulation of auditory receptor cell differentiation GO:0045609 1 0.318
ectodermal placode formation GO:0060788 16 0.315
mesenchymal cell differentiation GO:0048762 107 0.313
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.313
epithelial cell maturation involved in prostate gland development GO:0060743 4 0.313
morphogenesis of an epithelial sheet GO:0002011 27 0.313
transforming growth factor beta receptor signaling pathway involved in primitive streak formation GO:0090010 1 0.310
positive regulation of transcription from rna polymerase ii promoter by glucose GO:0000432 3 0.310
spinal cord motor neuron differentiation GO:0021522 35 0.307
neuron migration GO:0001764 122 0.301
Mouse Worm
smad protein complex assembly GO:0007183 1 0.298
bone development GO:0060348 120 0.294
negative regulation of apoptotic process involved in outflow tract morphogenesis GO:1902257 2 0.290
positive regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901228 4 0.285
olfactory bulb interneuron development GO:0021891 7 0.283
Mouse
artery development GO:0060840 53 0.282
primary prostatic bud elongation GO:0060516 2 0.282
leukocyte differentiation GO:0002521 342 0.281
cell fate specification GO:0001708 72 0.279
Worm
ectodermal placode morphogenesis GO:0071697 16 0.279
regulation of mesenchymal cell apoptotic process GO:2001053 14 0.272
negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis GO:0072040 4 0.269
regulation of cell cycle GO:0051726 281 0.268
aorta morphogenesis GO:0035909 22 0.267
ear morphogenesis GO:0042471 118 0.267
lens morphogenesis in camera type eye GO:0002089 24 0.264
morphogenesis of embryonic epithelium GO:0016331 159 0.259
dna metabolic process GO:0006259 303 0.259
positive regulation of tendon cell differentiation GO:2001051 1 0.259
negative regulation of stem cell maintenance GO:1902455 4 0.258
embryonic heart tube formation GO:0003144 1 0.258
lymphocyte differentiation GO:0030098 242 0.256
regulation of transcription from rna polymerase iii promoter GO:0006359 2 0.256
epithelial to mesenchymal transition GO:0001837 47 0.256
his purkinje system cell differentiation GO:0060932 2 0.255
cellular response to lipid GO:0071396 145 0.255
roof plate formation GO:0021509 1 0.250
hindbrain tangential cell migration GO:0021934 2 0.246
stem cell differentiation GO:0048863 268 0.244
chondrocyte development GO:0002063 24 0.244
retina development in camera type eye GO:0060041 119 0.242
Mouse
regulation of lens epithelial cell proliferation GO:2001109 1 0.241
forebrain regionalization GO:0021871 25 0.239
central nervous system neuron development GO:0021954 67 0.239
Mouse
neural tube patterning GO:0021532 43 0.238
germ line sex determination GO:0018992 3 0.237
bone morphogenesis GO:0060349 78 0.234
visual perception GO:0007601 52 0.233
Mouse
branching involved in ureteric bud morphogenesis GO:0001658 56 0.233
negative regulation of transcription from rna polymerase ii promoter by glucose GO:0000433 1 0.232
regulation of skeletal muscle cell differentiation GO:2001014 11 0.229
telencephalon regionalization GO:0021978 14 0.227
catagen GO:0042637 5 0.226
vagus nerve morphogenesis GO:0021644 2 0.226
regulation of cell adhesion GO:0030155 154 0.225
parasympathetic nervous system development GO:0048486 19 0.223
noradrenergic neuron differentiation GO:0003357 6 0.222
neural plate morphogenesis GO:0001839 9 0.221
mesonephric tubule morphogenesis GO:0072171 63 0.221
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.219
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.219
tendon cell differentiation GO:0035990 4 0.219
astrocyte fate commitment GO:0060018 4 0.218
endodermal cell fate specification GO:0001714 4 0.216
metanephric nephron tubule formation GO:0072289 4 0.215
vagus nerve development GO:0021564 3 0.215
carbon catabolite activation of transcription GO:0045991 4 0.214
regulation of endodermal cell fate specification GO:0042663 2 0.214
urogenital system development GO:0001655 261 0.213
ascending aorta morphogenesis GO:0035910 3 0.209
ossification GO:0001503 216 0.208
glomerular mesangial cell development GO:0072144 3 0.200
negative regulation of neuron differentiation GO:0045665 101 0.200
ventral spinal cord development GO:0021517 48 0.199
epithelial cell development GO:0002064 159 0.198
tube closure GO:0060606 91 0.198
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 2 0.193
regulation of organ growth GO:0046620 61 0.192
Mouse
locus ceruleus development GO:0021703 1 0.191
regulation of proteolysis GO:0030162 164 0.190
regulation of vascular wound healing GO:0061043 2 0.190
medulla oblongata development GO:0021550 3 0.188
negative regulation of gastrulation GO:2000542 3 0.188
metanephric capsule formation GO:0072266 1 0.188
cell maturation GO:0048469 127 0.187
Mouse
digestion GO:0007586 40 0.187
Mouse
negative regulation of photoreceptor cell differentiation GO:0046533 4 0.186
single organism cell adhesion GO:0098602 156 0.184
positive regulation of apoptotic process GO:0043065 217 0.178
bmp signaling pathway involved in heart development GO:0061312 2 0.175
vascular wound healing GO:0061042 3 0.175
oocyte axis specification GO:0007309 2 0.174
embryonic nail plate morphogenesis GO:0035880 3 0.172
forebrain radial glial cell differentiation GO:0021861 4 0.166
axial mesodermal cell fate specification GO:0048327 1 0.166
regulation of stem cell maintenance GO:2000036 17 0.163
chemotaxis GO:0006935 247 0.162
Mouse
positive regulation of epithelial cell proliferation GO:0050679 68 0.161
embryonic skeletal joint development GO:0072498 13 0.160
gliogenesis GO:0042063 141 0.160
cardiac muscle cell development GO:0055013 39 0.159
mesoderm development GO:0007498 100 0.159
palate development GO:0060021 76 0.159
tangential migration from the subventricular zone to the olfactory bulb GO:0022028 5 0.158
Mouse
regulation of cardiac chamber formation GO:1901210 1 0.157
positive regulation of bmp signaling pathway GO:0030513 23 0.157
eye photoreceptor cell differentiation GO:0001754 41 0.157
olfactory bulb development GO:0021772 30 0.156
Mouse
regulation of endocardial cushion to mesenchymal transition involved in heart valve formation GO:2000800 1 0.155
chondrocyte differentiation GO:0002062 72 0.154
regulation of apoptotic process involved in outflow tract morphogenesis GO:1902256 2 0.154
positive regulation of cell adhesion GO:0045785 80 0.153
blood vessel morphogenesis GO:0048514 285 0.153
septum primum development GO:0003284 4 0.153
closure of optic fissure GO:0061386 2 0.153
trachea cartilage morphogenesis GO:0060535 4 0.151
left lung development GO:0060459 4 0.151
germ cell development GO:0007281 185 0.150
renal tubule development GO:0061326 87 0.150
mesenchymal cell development GO:0014031 93 0.149
axial mesoderm formation GO:0048320 3 0.149
carbon catabolite repression of transcription GO:0045013 1 0.149
positive regulation of growth GO:0045927 104 0.148
Mouse
tricuspid valve development GO:0003175 3 0.148
stem cell proliferation GO:0072089 117 0.146
male gamete generation GO:0048232 285 0.144
blastocyst formation GO:0001825 33 0.143
somitogenesis GO:0001756 69 0.143
optic vesicle morphogenesis GO:0003404 2 0.143
positive regulation of stem cell proliferation GO:2000648 59 0.142
olfactory bulb interneuron differentiation GO:0021889 12 0.142
Mouse
ureteric bud development GO:0001657 94 0.141
regulation of bmp signaling pathway GO:0030510 60 0.141
cranial nerve formation GO:0021603 4 0.139
preganglionic parasympathetic nervous system development GO:0021783 17 0.138
nephron tubule development GO:0072080 84 0.137
inner cell mass cellular morphogenesis GO:0001828 1 0.136
oocyte construction GO:0007308 2 0.134
pallium development GO:0021543 120 0.132
Mouse
pulmonary valve formation GO:0003193 1 0.130
axial mesodermal cell differentiation GO:0048321 1 0.128
dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis GO:0060598 2 0.128
negative regulation of transcription by glucose GO:0045014 1 0.127
notochord formation GO:0014028 5 0.126
regulation of cardiac chamber morphogenesis GO:1901219 2 0.126
spermatid differentiation GO:0048515 115 0.126
negative regulation of immune system process GO:0002683 209 0.124
neural retina development GO:0003407 41 0.123
Mouse
tongue muscle cell differentiation GO:0035981 2 0.122
deltoid tuberosity development GO:0035993 3 0.121
tooth mineralization GO:0034505 9 0.121
cardioblast differentiation GO:0010002 13 0.120
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.120
positive regulation of chondrocyte differentiation GO:0032332 13 0.119
carbohydrate homeostasis GO:0033500 128 0.119
cellular component assembly involved in morphogenesis GO:0010927 139 0.118
regulation of stem cell differentiation GO:2000736 50 0.118
cerebral cortex neuron differentiation GO:0021895 19 0.118
Mouse
skeletal muscle fiber differentiation GO:0098528 5 0.118
regulation of transcription involved in cell fate commitment GO:0060850 15 0.117
smooth muscle tissue development GO:0048745 22 0.117
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.117
cardiac left ventricle formation GO:0003218 1 0.112
detection of mechanical stimulus involved in equilibrioception GO:0050973 2 0.112
spinal cord development GO:0021510 81 0.112
regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000148 1 0.111
positive regulation of vascular wound healing GO:0035470 1 0.111
kidney morphogenesis GO:0060993 83 0.111
regulation of chondrocyte differentiation GO:0032330 33 0.110
positive regulation of lens epithelial cell proliferation GO:2001111 1 0.109
odontogenesis GO:0042476 78 0.108
sensory perception of light stimulus GO:0050953 54 0.108
Mouse
neural precursor cell proliferation GO:0061351 121 0.107
Mouse
smad protein signal transduction GO:0060395 21 0.107
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.107
positive regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014718 2 0.105
positive regulation of transcription by glucose GO:0046016 3 0.105
negative regulation of heart looping GO:1901208 1 0.104
regulation of heart looping GO:1901207 1 0.104
social behavior GO:0035176 21 0.103
cerebral cortex gabaergic interneuron fate commitment GO:0021893 2 0.102
regulation of retina development in camera type eye GO:1902866 3 0.102
intestinal epithelial structure maintenance GO:0060729 4 0.102
visceral motor neuron differentiation GO:0021524 3 0.101
regulation of extracellular matrix assembly GO:1901201 2 0.101
negative regulation of nervous system development GO:0051961 156 0.101
smoothened signaling pathway GO:0007224 105 0.101
neural plate development GO:0001840 12 0.100
cerebral cortex radially oriented cell migration GO:0021799 31 0.100
regulation of lymphocyte mediated immunity GO:0002706 84 0.099
glomerular mesangial cell differentiation GO:0072008 3 0.099
negative regulation of cardiac chamber formation GO:1901211 1 0.099
epidermis morphogenesis GO:0048730 33 0.098
neural crest cell migration GO:0001755 32 0.098
cellular response to cholesterol GO:0071397 2 0.098
neural crest cell fate commitment GO:0014034 1 0.097
cell division GO:0051301 120 0.097
regulation of dna recombination GO:0000018 34 0.096
atrial ventricular junction remodeling GO:0003294 2 0.095
spermatid development GO:0007286 108 0.095
developmental maturation GO:0021700 193 0.094
Mouse
hair follicle development GO:0001942 85 0.094
regulation of mesenchymal cell proliferation GO:0010464 37 0.094
cardiac neural crest cell migration involved in outflow tract morphogenesis GO:0003253 3 0.094
regulation of transcription from rna polymerase ii promoter involved in forebrain neuron fate commitment GO:0021882 3 0.093
oocyte differentiation GO:0009994 35 0.093
skeletal muscle cell differentiation GO:0035914 66 0.093
regulation of heart morphogenesis GO:2000826 22 0.092
endothelial cell differentiation GO:0045446 41 0.091
embryonic camera type eye development GO:0031076 36 0.091
notch signaling pathway GO:0007219 71 0.091
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.091
cardiac cell fate specification GO:0060912 2 0.091
renal vesicle induction GO:0072034 3 0.090
ectodermal placode development GO:0071696 16 0.090
prostate gland morphogenesis GO:0060512 32 0.090
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.089
protein localization to organelle GO:0033365 185 0.089
mesoderm formation GO:0001707 62 0.089
response to acid chemical GO:0001101 111 0.089
endocardial cushion formation GO:0003272 13 0.089
cochlea morphogenesis GO:0090103 22 0.088
regulation of glomerular mesangial cell proliferation GO:0072124 1 0.088
embryonic eye morphogenesis GO:0048048 29 0.088
epiblast cell extraembryonic ectoderm cell signaling involved in anterior posterior axis specification GO:0060802 1 0.087
cardiac atrium morphogenesis GO:0003209 23 0.087
regulation of cartilage development GO:0061035 44 0.087
cardiac chamber development GO:0003205 108 0.086
positive regulation of extracellular matrix organization GO:1903055 4 0.086
morphogenesis of a branching epithelium GO:0061138 193 0.086
oogenesis GO:0048477 56 0.086
branching morphogenesis of an epithelial tube GO:0048754 159 0.085
negative regulation of glial cell proliferation GO:0060253 4 0.085
mesangial cell differentiation GO:0072007 4 0.084
fat cell differentiation GO:0045444 160 0.084
covalent chromatin modification GO:0016569 163 0.084
activation of meiosis GO:0090427 4 0.083
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.083
chromatin organization GO:0006325 206 0.083
nephron tubule morphogenesis GO:0072078 68 0.082
cardiac atrium development GO:0003230 24 0.082
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.082
paraxial mesodermal cell fate commitment GO:0048343 2 0.082
positive regulation of skeletal muscle fiber differentiation GO:1902811 2 0.081
negative regulation of prostatic bud formation GO:0060686 4 0.081
telencephalon cell migration GO:0022029 55 0.080
Mouse
neural tube development GO:0021915 160 0.080
skin development GO:0043588 220 0.080
substrate independent telencephalic tangential interneuron migration GO:0021843 8 0.080
Mouse
hemangioblast cell differentiation GO:0060217 1 0.079
t cell differentiation GO:0030217 174 0.079
regulation of striated muscle cell differentiation GO:0051153 81 0.079
cerebral cortex development GO:0021987 86 0.079
Mouse
positive regulation of dendrite development GO:1900006 21 0.078
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.078
negative regulation of mesenchymal cell apoptotic process GO:2001054 11 0.078
odontogenesis of dentin containing tooth GO:0042475 66 0.077
mrna transcription from rna polymerase ii promoter GO:0042789 4 0.077
neural crest cell development GO:0014032 48 0.077
embryonic heart tube elongation GO:0036306 1 0.076
stem cell fate specification GO:0048866 3 0.076
positive regulation of organ growth GO:0046622 29 0.076
Mouse
cell proliferation in midbrain GO:0033278 2 0.076
positive regulation of mesenchymal cell apoptotic process GO:2001055 3 0.076
inhibition of neuroepithelial cell differentiation GO:0002085 2 0.076
mammary gland morphogenesis GO:0060443 54 0.076
sinoatrial node cell development GO:0060931 3 0.076
noradrenergic neuron development GO:0003358 3 0.075
corticotropin hormone secreting cell differentiation GO:0060128 3 0.075
regulation of satellite cell activation involved in skeletal muscle regeneration GO:0014717 3 0.074
regulation of apoptotic process involved in morphogenesis GO:1902337 10 0.074
inner ear receptor cell differentiation GO:0060113 61 0.074
regulation of transcription from rna polymerase ii promoter by glucose GO:0000430 3 0.074
cellular chemical homeostasis GO:0055082 215 0.074
cellular response to monosaccharide stimulus GO:0071326 47 0.073
regulation of branch elongation involved in ureteric bud branching GO:0072095 3 0.073
nephrogenic mesenchyme development GO:0072076 3 0.073
single fertilization GO:0007338 82 0.073
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.072
sinoatrial node development GO:0003163 4 0.072
axis elongation involved in somitogenesis GO:0090245 4 0.072
gall bladder development GO:0061010 2 0.071
endoderm formation GO:0001706 20 0.071
myotome development GO:0061055 4 0.071
carbon catabolite regulation of transcription GO:0045990 4 0.071
single organismal cell cell adhesion GO:0016337 131 0.071
negative regulation of bmp signaling pathway GO:0030514 35 0.070
development of primary sexual characteristics GO:0045137 143 0.070
kidney development GO:0001822 213 0.069
protein localization to nucleus GO:0034504 121 0.069
regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 0.069
otolith morphogenesis GO:0032474 3 0.069
regulation of leukocyte differentiation GO:1902105 159 0.069
smoothened signaling pathway involved in ventral spinal cord patterning GO:0021910 7 0.068
female sex determination GO:0030237 1 0.068
negative regulation of endodermal cell differentiation GO:1903225 1 0.068
cell migration involved in gastrulation GO:0042074 13 0.067
negative regulation of gliogenesis GO:0014014 23 0.066
commitment of multipotent stem cells to neuronal lineage in forebrain GO:0021898 3 0.066
liver development GO:0001889 66 0.065
endothelium development GO:0003158 45 0.064
ventricular zone neuroblast division GO:0021847 3 0.064
sensory perception GO:0007600 245 0.064
Mouse
regulation of gastrulation GO:0010470 16 0.064
negative regulation of striated muscle cell differentiation GO:0051154 14 0.063
multi organism behavior GO:0051705 62 0.063
Worm
angiogenesis GO:0001525 201 0.063
otic vesicle formation GO:0030916 8 0.063
spinal cord motor neuron cell fate specification GO:0021520 13 0.062
negative regulation of keratinocyte differentiation GO:0045617 4 0.062
positive regulation of cartilage development GO:0061036 18 0.062
cardiocyte differentiation GO:0035051 87 0.062
positive regulation of transcription from rna polymerase iii promoter GO:0045945 1 0.062
fibroblast growth factor receptor signaling pathway involved in mammary gland specification GO:0060595 2 0.062
telencephalon development GO:0021537 186 0.062
Mouse
wound healing spreading of cells GO:0044319 8 0.062
negative regulation of osteoblast differentiation GO:0045668 30 0.062
endodermal cell fate determination GO:0007493 2 0.061
trachea cartilage development GO:0060534 8 0.061
melanocyte differentiation GO:0030318 25 0.061
negative regulation of stem cell differentiation GO:2000737 14 0.060
inner ear morphogenesis GO:0042472 101 0.060
renal capsule specification GO:0072130 1 0.060
respiratory system development GO:0060541 190 0.060
regulation of store operated calcium channel activity GO:1901339 1 0.060
formation of radial glial scaffolds GO:0021943 4 0.060
cd8 positive alpha beta t cell differentiation involved in immune response GO:0002302 2 0.060
regulation of cell proliferation involved in tissue homeostasis GO:0060784 1 0.060
middle ear morphogenesis GO:0042474 23 0.059
positive regulation of apoptotic signaling pathway GO:2001235 95 0.059
ventricular septum morphogenesis GO:0060412 27 0.059
cell proliferation in hindbrain GO:0021534 10 0.059
morphogenesis of an epithelial fold GO:0060571 28 0.059
mitral valve development GO:0003174 4 0.058
digestive tract development GO:0048565 190 0.058
Mouse
outer ear morphogenesis GO:0042473 5 0.058
cranial nerve development GO:0021545 41 0.058
pharynx development GO:0060465 1 0.058
positive regulation of striated muscle tissue development GO:0045844 31 0.058
heart field specification GO:0003128 6 0.058
negative regulation of apoptotic process involved in morphogenesis GO:1902338 6 0.058
negative regulation of hexokinase activity GO:1903300 4 0.057
cardiac right ventricle formation GO:0003219 3 0.057
negative regulation of chondrocyte differentiation GO:0032331 13 0.057
optic nerve formation GO:0021634 1 0.056
enamel mineralization GO:0070166 7 0.056
hindlimb morphogenesis GO:0035137 42 0.056
Mouse
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis GO:2000166 1 0.056
mesodermal cell migration GO:0008078 4 0.056
epidermis development GO:0008544 187 0.055
negative regulation of striated muscle tissue development GO:0045843 18 0.055
regulation of protein stability GO:0031647 52 0.054
branch elongation involved in ureteric bud branching GO:0060681 3 0.054
mechanoreceptor differentiation GO:0042490 67 0.054
lipid homeostasis GO:0055088 63 0.054
negative regulation of astrocyte differentiation GO:0048712 10 0.054
regulation of myotube differentiation GO:0010830 62 0.054
pattern specification involved in metanephros development GO:0072268 4 0.054
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 4 0.054
axonogenesis involved in innervation GO:0060385 5 0.054
regulation of tendon cell differentiation GO:2001049 1 0.053
organ growth GO:0035265 117 0.053
Mouse
organic hydroxy compound metabolic process GO:1901615 203 0.053
somatic stem cell maintenance GO:0035019 47 0.053
regulation of stem cell division GO:2000035 4 0.053
neuroblast differentiation GO:0014016 2 0.053
endocardial cell differentiation GO:0060956 4 0.053
endocytosis GO:0006897 168 0.053
dendrite development GO:0016358 115 0.052
smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation GO:0021938 4 0.052
forebrain morphogenesis GO:0048853 17 0.052
regulation of ossification GO:0030278 112 0.052
dna catabolic process endonucleolytic GO:0000737 15 0.052
skeletal muscle satellite cell differentiation GO:0014816 6 0.052
myotube differentiation GO:0014902 105 0.052
neural fold formation GO:0001842 7 0.052
chromatin modification GO:0016568 187 0.052
regulation of canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060827 1 0.052
negative regulation of glomerular mesangial cell proliferation GO:0072125 1 0.051
negative regulation of protein metabolic process GO:0051248 282 0.051
connective tissue development GO:0061448 179 0.051
gonad development GO:0008406 141 0.051
satellite cell activation involved in skeletal muscle regeneration GO:0014901 3 0.051
otic vesicle development GO:0071599 14 0.051

Alx1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.578
musculoskeletal system disease DOID:17 0 0.578
connective tissue disease DOID:65 0 0.236
bone disease DOID:0080001 0 0.157
osteochondrodysplasia DOID:2256 0 0.142
bone development disease DOID:0080006 0 0.142
physical disorder DOID:0080015 0 0.108
cancer DOID:162 0 0.086
disease of cellular proliferation DOID:14566 0 0.086
dysostosis DOID:1934 0 0.065