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Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of chondrocyte differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of chondrocyte differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
Shh	sonic hedgehog	1.000
Sox9	SRY-box containing gene 9	0.999
Fgf8	fibroblast growth factor 8	0.999
Fgfr2	fibroblast growth factor receptor 2	0.998
Gli2	GLI-Kruppel family member GLI2	0.997
Foxc1	forkhead box C1	0.990
Bmp4	bone morphogenetic protein 4	0.988
Smo	smoothened homolog (Drosophila)	0.988
Rarg	retinoic acid receptor, gamma	0.983
Fgfr1	fibroblast growth factor receptor 1	0.981
Prrx1	paired related homeobox 1	0.973
Pax2	paired box gene 2	0.973
Tcfap2a	transcription factor AP-2, alpha	0.961
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.957
Tbx1	T-box 1	0.948
Tgfbr2	transforming growth factor, beta receptor II	0.937	Mouse
Tgfb2	transforming growth factor, beta 2	0.935
Pax3	paired box gene 3	0.932
Fgfr3	fibroblast growth factor receptor 3	0.930
Prrx2	paired related homeobox 2	0.917
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.895
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.870
Chrd	chordin	0.855
Otx2	orthodenticle homolog 2 (Drosophila)	0.840
Nodal	nodal	0.834
Msx1	homeobox, msh-like 1	0.834
Bmp7	bone morphogenetic protein 7	0.761
Hand1	heart and neural crest derivatives expressed transcript 1	0.761
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.726
Alx4	aristaless-like homeobox 4	0.719
Gli3	GLI-Kruppel family member GLI3	0.705	Mouse
Wnt3a	wingless-related MMTV integration site 3A	0.679	Mouse
Fgf10	fibroblast growth factor 10	0.669
Dlx5	distal-less homeobox 5	0.647
Nog	noggin	0.607
Hand2	heart and neural crest derivatives expressed transcript 2	0.559
Acvr1	activin A receptor, type 1	0.542	Mouse
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.519
Eya1	eyes absent 1 homolog (Drosophila)	0.495
Hoxa1	homeobox A1	0.492
Lhx1	LIM homeobox protein 1	0.484
Isl1	ISL1 transcription factor, LIM/homeodomain	0.464
Pitx2	paired-like homeodomain transcription factor 2	0.459
Hoxa2	homeobox A2	0.440
Pax8	paired box gene 8	0.436
Msx2	homeobox, msh-like 2	0.434
Foxc2	forkhead box C2	0.410
Runx2	runt related transcription factor 2	0.407
Rarb	retinoic acid receptor, beta	0.393
Meox2	mesenchyme homeobox 2	0.387
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.383	Mouse
Wnt4	wingless-related MMTV integration site 4	0.383	Mouse
Col2a1	collagen, type II, alpha 1	0.375
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.373
Gata4	GATA binding protein 4	0.372
Jag1	jagged 1	0.335
Gbx2	gastrulation brain homeobox 2	0.322
Rara	retinoic acid receptor, alpha	0.287	Mouse
Gas1	growth arrest specific 1	0.286
Fgf3	fibroblast growth factor 3	0.272
Hes1	hairy and enhancer of split 1 (Drosophila)	0.259
Nos3	nitric oxide synthase 3, endothelial cell	0.256
Emx2	empty spiracles homolog 2 (Drosophila)	0.255
Smad6	MAD homolog 6 (Drosophila)	0.245
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.244
Ednra	endothelin receptor type A	0.239
Pax6	paired box gene 6	0.236
Hoxd13	homeobox D13	0.223
Ctnnb1	catenin (cadherin associated protein), beta 1	0.220
Alx3	aristaless-like homeobox 3	0.220
Twist2	twist homolog 2 (Drosophila)	0.190
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.182	Mouse
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.182
Lmx1a	LIM homeobox transcription factor 1 alpha	0.172
Gdnf	glial cell line derived neurotrophic factor	0.172
En1	engrailed 1	0.166
Pitx1	paired-like homeodomain transcription factor 1	0.164
Fzd8	frizzled homolog 8 (Drosophila)	0.159
Otx1	orthodenticle homolog 1 (Drosophila)	0.156
Ptch1	patched homolog 1	0.152
Apc	adenomatosis polyposis coli	0.149
Rxra	retinoid X receptor alpha	0.140
Nkx3-2	NK3 homeobox 2	0.120
Hoxa3	homeobox A3	0.119
Hoxd11	homeobox D11	0.115
Ret	ret proto-oncogene	0.112
Sox3	SRY-box containing gene 3	0.105	Mouse
Fbn1	fibrillin 1	0.101
Fgfrl1	fibroblast growth factor receptor-like 1	0.099
Sox2	SRY-box containing gene 2	0.099	Mouse
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.098
Pbx1	pre B-cell leukemia transcription factor 1	0.093
Ntf3	neurotrophin 3	0.089
Eln	elastin	0.087
Gata6	GATA binding protein 6	0.087
Pten	phosphatase and tensin homolog	0.085
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.084
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.081
Idua	iduronidase, alpha-L-	0.079
Insm1	insulinoma-associated 1	0.079
Btbd17	BTB (POZ) domain containing 17	0.077
Pthlh	parathyroid hormone-like peptide	0.075
Wnt5a	wingless-related MMTV integration site 5A	0.074	Mouse
Nf1	neurofibromatosis 1	0.074
Pax9	paired box gene 9	0.073
Nkx6-1	NK6 homeobox 1	0.072
Bmp2	bone morphogenetic protein 2	0.069	Mouse
Wnt6	wingless-related MMTV integration site 6	0.068	Mouse
Lmx1b	LIM homeobox transcription factor 1 beta	0.066
Vegfa	vascular endothelial growth factor A	0.066
Fgf18	fibroblast growth factor 18	0.063
Tcf21	transcription factor 21	0.061
Smad3	MAD homolog 3 (Drosophila)	0.060
Gja1	gap junction protein, alpha 1	0.060
Fzd1	frizzled homolog 1 (Drosophila)	0.059
Foxh1	forkhead box H1	0.059
Alx1	ALX homeobox 1	0.057
Gpc3	glypican 3	0.056
Emx1	empty spiracles homolog 1 (Drosophila)	0.055
Rbl2	retinoblastoma-like 2	0.055
Mrc2	mannose receptor, C type 2	0.054
Fzd2	frizzled homolog 2 (Drosophila)	0.054
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.052
Col11a1	collagen, type XI, alpha 1	0.051
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.051
Bmper	BMP-binding endothelial regulator	0.050
Snai1	snail homolog 1 (Drosophila)	0.050
Fgf17	fibroblast growth factor 17	0.050
Hoxa11	homeobox A11	0.050
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.050
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.049
Tbx2	T-box 2	0.049
Chd7	chromodomain helicase DNA binding protein 7	0.048
Neurog3	neurogenin 3	0.047
Zfp503	zinc finger protein 503	0.046
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.046
Ihh	Indian hedgehog	0.046
Trp63	transformation related protein 63	0.046
Npr2	natriuretic peptide receptor 2	0.045
Hoxa5	homeobox A5	0.044
Foxa2	forkhead box A2	0.043
Epas1	endothelial PAS domain protein 1	0.042
Hoxb6	homeobox B6	0.042
Tbx3	T-box 3	0.041
Tbx15	T-box 15	0.041
Nkx2-1	NK2 homeobox 1	0.039	Mouse
Hoxa13	homeobox A13	0.039
Fgf15	fibroblast growth factor 15	0.039
Lef1	lymphoid enhancer binding factor 1	0.039
Wnt9b	wingless-type MMTV integration site 9B	0.038	Mouse
Pou3f3	POU domain, class 3, transcription factor 3	0.037
Zic3	zinc finger protein of the cerebellum 3	0.037
Hoxd3	homeobox D3	0.037
Foxg1	forkhead box G1	0.036
Eng	endoglin	0.035
Efna4	ephrin A4	0.035
Hoxc5	homeobox C5	0.035
Atoh7	atonal homolog 7 (Drosophila)	0.034
Bnc1	basonuclin 1	0.034
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.034
Lhx3	LIM homeobox protein 3	0.033
Emp2	epithelial membrane protein 2	0.033
Esr1	estrogen receptor 1 (alpha)	0.032
Ece1	endothelin converting enzyme 1	0.032
Npr3	natriuretic peptide receptor 3	0.032
Col1a1	collagen, type I, alpha 1	0.031
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.031
Adra2b	adrenergic receptor, alpha 2b	0.031
Thrb	thyroid hormone receptor beta	0.030	Mouse
Gja5	gap junction protein, alpha 5	0.030
Sall4	sal-like 4 (Drosophila)	0.030
Mmp2	matrix metallopeptidase 2	0.030
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.029
Gsc	goosecoid homeobox	0.029
Tbx5	T-box 5	0.029
Tgfb1i1	transforming growth factor beta 1 induced transcript 1	0.029
Twist1	twist homolog 1 (Drosophila)	0.029
Efs	embryonal Fyn-associated substrate	0.028
Mesp1	mesoderm posterior 1	0.028
Vangl2	vang-like 2 (van gogh, Drosophila)	0.028
Matn4	matrilin 4	0.028
Sox7	SRY-box containing gene 7	0.028	Mouse
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.028
Vax1	ventral anterior homeobox containing gene 1	0.027
Tcf15	transcription factor 15	0.027
Wt1	Wilms tumor 1 homolog	0.027
Kl	klotho	0.026
Zeb1	zinc finger E-box binding homeobox 1	0.026
Gpr27	G protein-coupled receptor 27	0.026
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.026
Grb10	growth factor receptor bound protein 10	0.025
Aplnr	apelin receptor	0.025
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.024
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.024
Tenc1	tensin like C1 domain-containing phosphatase	0.024
Sox17	SRY-box containing gene 17	0.024	Mouse
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.024
Otp	orthopedia homolog (Drosophila)	0.023
Notch3	Notch gene homolog 3 (Drosophila)	0.023
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.023
Col13a1	collagen, type XIII, alpha 1	0.022
Hic1	hypermethylated in cancer 1	0.022
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.022	Mouse
Sox18	SRY-box containing gene 18	0.022	Mouse
Lrp6	low density lipoprotein receptor-related protein 6	0.022
Efna2	ephrin A2	0.021
Npas1	neuronal PAS domain protein 1	0.021
Foxf1a	forkhead box F1a	0.021
Tcf7l1	transcription factor 7-like 1 (T-cell specific, HMG box)	0.021
Tgfbr3	transforming growth factor, beta receptor III	0.021
Hoxb4	homeobox B4	0.020
Gdf3	growth differentiation factor 3	0.020	Mouse
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.020	Mouse
Bmp5	bone morphogenetic protein 5	0.020
Gata3	GATA binding protein 3	0.020
Sox4	SRY-box containing gene 4	0.020	Mouse
Efnb2	ephrin B2	0.019
Ephb3	Eph receptor B3	0.019
Lrp2	low density lipoprotein receptor-related protein 2	0.019
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.019
Arx	aristaless related homeobox	0.019
Angptl2	angiopoietin-like 2	0.019
Fzd4	frizzled homolog 4 (Drosophila)	0.019
Gdf11	growth differentiation factor 11	0.019
Hoxb13	homeobox B13	0.018
Wnt9a	wingless-type MMTV integration site 9A	0.018
Foxd2	forkhead box D2	0.018
Nrtn	neurturin	0.018
Rspo1	R-spondin homolog (Xenopus laevis)	0.018
Pou3f1	POU domain, class 3, transcription factor 1	0.018
Zfp703	zinc finger protein 703	0.018
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.018
Fgf2	fibroblast growth factor 2	0.017
She	src homology 2 domain-containing transforming protein E	0.017
Sall3	sal-like 3 (Drosophila)	0.017
Amh	anti-Mullerian hormone	0.017
Gli1	GLI-Kruppel family member GLI1	0.017	Mouse
Acan	aggrecan	0.017
Osr1	odd-skipped related 1 (Drosophila)	0.017
Pax1	paired box gene 1	0.017
Fgf9	fibroblast growth factor 9	0.016
Sim2	single-minded homolog 2 (Drosophila)	0.016
Chrng	cholinergic receptor, nicotinic, gamma polypeptide	0.016
Amhr2	anti-Mullerian hormone type 2 receptor	0.016	Mouse
Sod3	superoxide dismutase 3, extracellular	0.016
Pdgfb	platelet derived growth factor, B polypeptide	0.016
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.016
Hoxa7	homeobox A7	0.016
Foxn1	forkhead box N1	0.016
Irx3	Iroquois related homeobox 3 (Drosophila)	0.016
Slc16a2	solute carrier family 16 (monocarboxylic acid transporters), member 2	0.016
Fzd10	frizzled homolog 10 (Drosophila)	0.015
Sema3b	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	0.015
Tgfbr1	transforming growth factor, beta receptor I	0.015
Fzd7	frizzled homolog 7 (Drosophila)	0.015
En2	engrailed 2	0.015
Fgf5	fibroblast growth factor 5	0.015
Foxi3	forkhead box I3	0.015
Ednrb	endothelin receptor type B	0.015
Zfpm2	zinc finger protein, multitype 2	0.014
Hoxb3	homeobox B3	0.014
Trp53	transformation related protein 53	0.014
Gdf10	growth differentiation factor 10	0.014
Tctex1d4	Tctex1 domain containing 4	0.014
Smad7	MAD homolog 7 (Drosophila)	0.014
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.014
Hoxb5	homeobox B5	0.014
Ptrf	polymerase I and transcript release factor	0.014
Plcd1	phospholipase C, delta 1	0.014
Capn6	calpain 6	0.014
Sorbs3	sorbin and SH3 domain containing 3	0.014
Clcnka	chloride channel Ka	0.014
Ar	androgen receptor	0.014
Sox1	SRY-box containing gene 1	0.013
Cdc42ep1	CDC42 effector protein (Rho GTPase binding) 1	0.013
Ren1	renin 1 structural	0.013
Mn1	meningioma 1	0.013
Dkk2	dickkopf homolog 2 (Xenopus laevis)	0.013
Fam65c	family with sequence similarity 65, member C	0.013
Gdf1	growth differentiation factor 1	0.013	Mouse
Ghr	growth hormone receptor	0.013
Hoxc8	homeobox C8	0.013
Fgf4	fibroblast growth factor 4	0.013
Lrp5	low density lipoprotein receptor-related protein 5	0.013
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.013
Kitl	kit ligand	0.012
Jup	junction plakoglobin	0.012	Mouse
Apcdd1	adenomatosis polyposis coli down-regulated 1	0.012
Gdf5	growth differentiation factor 5	0.012
Pkd1	polycystic kidney disease 1 homolog	0.012
Hoxc6	homeobox C6	0.012
Crlf1	cytokine receptor-like factor 1	0.012
Smoc2	SPARC related modular calcium binding 2	0.012
Foxl2	forkhead box L2	0.012
Hoxc4	homeobox C4	0.012
Tdgf1	teratocarcinoma-derived growth factor 1	0.012
Hoxc9	homeobox C9	0.012
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.012
Mmp11	matrix metallopeptidase 11	0.012
Esr2	estrogen receptor 2 (beta)	0.012
Kcnk3	potassium channel, subfamily K, member 3	0.012
Angpt4	angiopoietin 4	0.012
Nkx2-4	NK2 transcription factor related, locus 4 (Drosophila)	0.012	Mouse
Glis3	GLIS family zinc finger 3	0.012	Mouse
Cpz	carboxypeptidase Z	0.012
Barx2	BarH-like homeobox 2	0.012
Acvrl1	activin A receptor, type II-like 1	0.011	Mouse
Dbp	D site albumin promoter binding protein	0.011
Lhx5	LIM homeobox protein 5	0.011
Bik	BCL2-interacting killer	0.011
Leprel2	leprecan-like 2	0.011
Rem1	rad and gem related GTP binding protein 1	0.011
Sox13	SRY-box containing gene 13	0.011
Wnt2b	wingless related MMTV integration site 2b	0.011	Mouse
Pitx3	paired-like homeodomain transcription factor 3	0.011
Irs1	insulin receptor substrate 1	0.011
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.011
Gata5	GATA binding protein 5	0.011
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.011
Omp	olfactory marker protein	0.011
Thbs3	thrombospondin 3	0.011
Msx3	homeobox, msh-like 3	0.011
Dmbx1	diencephalon/mesencephalon homeobox 1	0.011
Ephb4	Eph receptor B4	0.011
Neurog1	neurogenin 1	0.011
Olig2	oligodendrocyte transcription factor 2	0.011
Col4a5	collagen, type IV, alpha 5	0.011
Efnb1	ephrin B1	0.011
Mfap4	microfibrillar-associated protein 4	0.011
Pcsk6	proprotein convertase subtilisin/kexin type 6	0.010
Foxd1	forkhead box D1	0.010
Meis2	Meis homeobox 2	0.010
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.010
Cdx1	caudal type homeobox 1	0.010
Sycn	syncollin	0.010
Rax	retina and anterior neural fold homeobox	0.010
Nkx2-6	NK2 transcription factor related, locus 6 (Drosophila)	0.010	Mouse
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.010
Wnt3	wingless-related MMTV integration site 3	0.010	Mouse
Uncx	UNC homeobox	0.010
Barx1	BarH-like homeobox 1	0.010
Cxadr	coxsackie virus and adenovirus receptor	0.010
A530016L24Rik	RIKEN cDNA A530016L24 gene	0.010
Fxyd2	FXYD domain-containing ion transport regulator 2	0.010
Gpr3	G-protein coupled receptor 3	0.010
Inhbb	inhibin beta-B	0.010