Mus musculus

290 known processes

Bak1

BCL2-antagonist/killer 1

(Aliases: N-Bak,N-BAK1,Bak)

Bak1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
mitochondrial fusion GO:0008053 9 1.000
positive regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902110 11 0.994
Mouse
mitochondrial outer membrane permeabilization involved in programmed cell death GO:1902686 11 0.992
Mouse
positive regulation of mitochondrion organization GO:0010822 17 0.990
Worm
positive regulation of skeletal muscle fiber development GO:0048743 3 0.962
Mouse
regulation of pigment cell differentiation GO:0050932 7 0.955
Mouse
regulation of mammary gland involution GO:1903519 4 0.917
Mouse
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 4 0.891
Mouse
regulation of mitochondrion organization GO:0010821 27 0.891
Worm
protein insertion into mitochondrial membrane involved in apoptotic signaling pathway GO:0001844 4 0.844
Mouse
mitochondrion organization GO:0007005 134 0.819
apoptotic process involved in mammary gland involution GO:0060057 4 0.810
Mouse
organelle fusion GO:0048284 28 0.801
t cell homeostatic proliferation GO:0001777 4 0.791
Mouse
regulation of mitochondrial fission GO:0090140 3 0.778
regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001267 4 0.763
Mouse
membrane fusion GO:0061025 38 0.756
positive regulation of melanocyte differentiation GO:0045636 5 0.752
Mouse
response to endoplasmic reticulum stress GO:0034976 53 0.751
peptidyl amino acid modification GO:0018193 336 0.746
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001269 3 0.746
Mouse
necrotic cell death GO:0070265 30 0.746
Mouse
positive regulation of release of cytochrome c from mitochondria GO:0090200 5 0.728
regulation of melanocyte differentiation GO:0045634 7 0.721
Mouse
cellular response to gamma radiation GO:0071480 4 0.688
Mouse
positive regulation of apoptotic process involved in morphogenesis GO:1902339 4 0.686
Mouse
positive regulation of neuron maturation GO:0014042 2 0.676
Mouse
cochlear nucleus development GO:0021747 4 0.667
Mouse
positive regulation of neuroepithelial cell differentiation GO:1902913 5 0.663
Mouse
cellular process regulating host cell cycle in response to virus GO:0060154 3 0.659
Mouse
positive regulation of cell maturation GO:1903431 4 0.625
Mouse
negative regulation of retinal cell programmed cell death GO:0046671 2 0.571
Mouse
activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c GO:0008635 4 0.557
cd8 positive alpha beta t cell lineage commitment GO:0043375 1 0.531
Mouse
viral process GO:0016032 41 0.525
Mouse
mitochondrion morphogenesis GO:0070584 13 0.504
Mouse
immune response activating signal transduction GO:0002757 116 0.479
activation of immune response GO:0002253 138 0.447
response to ischemia GO:0002931 14 0.445
Mouse
response to uv b GO:0010224 5 0.440
Mouse
release of cytochrome c from mitochondria GO:0001836 23 0.425
positive regulation of b cell apoptotic process GO:0002904 4 0.423
Mouse
post embryonic eye morphogenesis GO:0048050 4 0.418
cd4 positive or cd8 positive alpha beta t cell lineage commitment GO:0043369 8 0.415
Mouse
regulation of membrane permeability GO:0090559 18 0.407
Mouse
alpha beta t cell lineage commitment GO:0002363 7 0.405
Mouse
negative regulation of peptidyl serine phosphorylation GO:0033137 10 0.404
regulation of intrinsic apoptotic signaling pathway GO:2001242 61 0.400
Mouse
negative regulation of endoplasmic reticulum calcium ion concentration GO:0032471 3 0.398
response to osmotic stress GO:0006970 21 0.388
Mouse
regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway GO:1903376 3 0.378
Mouse
carbohydrate derivative biosynthetic process GO:1901137 183 0.376
Mouse
regulation of release of cytochrome c from mitochondria GO:0090199 11 0.375
positive regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway GO:1903378 3 0.370
Mouse
regulation of cell cycle GO:0051726 281 0.360
regulation of cellular ketone metabolic process GO:0010565 66 0.355
regulation of multi organism process GO:0043900 111 0.347
Mouse
cellular lipid metabolic process GO:0044255 323 0.347
Mouse
purine nucleoside metabolic process GO:0042278 241 0.345
Worm
mitochondrial membrane organization GO:0007006 26 0.345
Mouse
posttranscriptional regulation of gene expression GO:0010608 155 0.344
Mouse
t cell activation GO:0042110 289 0.338
Mouse
positive regulation of calcium ion transport into cytosol GO:0010524 9 0.334
programmed necrotic cell death GO:0097300 28 0.334
Mouse
calcium ion transport GO:0006816 159 0.332
apoptotic process involved in embryonic digit morphogenesis GO:1902263 3 0.330
Mouse
positive regulation of cellular response to oxidative stress GO:1900409 6 0.328
Mouse
membrane organization GO:0061024 245 0.328
regulation of nitrogen utilization GO:0006808 2 0.326
Mouse
response to amino acid GO:0043200 37 0.317
Mouse
regulation of cell cycle process GO:0010564 160 0.316
Mouse
interspecies interaction between organisms GO:0044419 83 0.315
Mouse
leukocyte proliferation GO:0070661 172 0.314
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.311
regulation of cellular amino acid metabolic process GO:0006521 5 0.310
apoptotic signaling pathway GO:0097190 306 0.308
regulation of organ morphogenesis GO:2000027 144 0.303
Mouse
striated muscle tissue development GO:0014706 293 0.299
Mouse
negative regulation of calcium ion transport into cytosol GO:0010523 2 0.299
Mouse
positive regulation of mitochondrial membrane permeability GO:0035794 12 0.298
Mouse
immune response regulating signaling pathway GO:0002764 125 0.293
cation transport GO:0006812 399 0.292
cellular ketone metabolic process GO:0042180 84 0.292
spermatid differentiation GO:0048515 115 0.289
Mouse
sensory organ morphogenesis GO:0090596 242 0.286
endoplasmic reticulum calcium ion homeostasis GO:0032469 11 0.284
muscle tissue development GO:0060537 308 0.277
Mouse
peptidyl threonine phosphorylation GO:0018107 31 0.273
Mouse
peptidyl serine modification GO:0018209 83 0.272
heterocycle catabolic process GO:0046700 280 0.272
Worm
cerebral cortex development GO:0021987 86 0.270
Mouse
regulation of developmental pigmentation GO:0048070 14 0.266
Mouse
male sex differentiation GO:0046661 109 0.264
Mouse
t cell lineage commitment GO:0002360 13 0.263
Mouse
peptidyl threonine modification GO:0018210 31 0.262
Mouse
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.259
Mouse
amine metabolic process GO:0009308 45 0.253
camera type eye development GO:0043010 266 0.252
regulation of cellular response to stress GO:0080135 159 0.250
Mouse
positive regulation of developmental pigmentation GO:0048087 6 0.249
Mouse
intrinsic apoptotic signaling pathway GO:0097193 132 0.249
cellular amino acid metabolic process GO:0006520 103 0.249
b cell proliferation GO:0042100 53 0.246
Mouse
skin development GO:0043588 220 0.242
Mouse
ion transmembrane transport GO:0034220 361 0.238
positive regulation of cellular amine metabolic process GO:0033240 5 0.236
t cell selection GO:0045058 34 0.235
Mouse
positive regulation of neuron apoptotic process GO:0043525 25 0.234
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.233
Mouse
stem cell differentiation GO:0048863 268 0.231
Mouse
metencephalon development GO:0022037 89 0.231
Mouse
regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902108 14 0.230
Mouse
regulation of organelle organization GO:0033043 289 0.229
Worm
negative regulation of phosphate metabolic process GO:0045936 184 0.229
ribonucleoside triphosphate catabolic process GO:0009203 199 0.226
Worm
actin cytoskeleton organization GO:0030036 220 0.223
Mouse
lymphocyte proliferation GO:0046651 164 0.220
Mouse
positive regulation of smooth muscle cell migration GO:0014911 4 0.218
Mouse
apoptotic mitochondrial changes GO:0008637 48 0.216
ribose phosphate metabolic process GO:0019693 291 0.212
Worm
actin filament organization GO:0007015 113 0.212
Mouse
telencephalon development GO:0021537 186 0.206
Mouse
positive regulation of protein oligomerization GO:0032461 4 0.205
peptidyl serine phosphorylation GO:0018105 74 0.205
mitochondrial fission GO:0000266 12 0.205
positive regulation of organelle organization GO:0010638 128 0.200
Worm
muscle cell differentiation GO:0042692 261 0.199
Mouse
skeletal muscle fiber development GO:0048741 58 0.198
Mouse
protein insertion into mitochondrial membrane GO:0051204 4 0.197
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.196
Worm
negative regulation of protein metabolic process GO:0051248 282 0.193
transmembrane transport GO:0055085 412 0.190
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.187
guanosine containing compound catabolic process GO:1901069 144 0.186
Worm
multicellular organismal homeostasis GO:0048871 164 0.185
Mouse
muscle cell development GO:0055001 133 0.185
Mouse
cell type specific apoptotic process GO:0097285 268 0.184
negative regulation of osteoblast proliferation GO:0033689 4 0.180
Mouse
mitochondrial transport GO:0006839 36 0.179
Mouse
antigen receptor mediated signaling pathway GO:0050851 64 0.178
positive regulation of mammary gland involution GO:1903521 4 0.176
Mouse
apoptotic process in bone marrow GO:0071839 1 0.172
Mouse
positive regulation of oxidative stress induced neuron death GO:1903223 3 0.171
Mouse
digestive tract development GO:0048565 190 0.170
Mouse
negative regulation of phosphorus metabolic process GO:0010563 184 0.170
protein processing GO:0016485 163 0.169
neuron apoptotic process GO:0051402 142 0.169
Mouse
purine nucleotide catabolic process GO:0006195 211 0.168
Worm
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 19 0.168
Mouse
b cell selection GO:0002339 3 0.167
cell aging GO:0007569 35 0.164
Mouse
regulation of protein stability GO:0031647 52 0.161
Mouse
regulation of neuron apoptotic process GO:0043523 122 0.160
Mouse
regulation of ion transport GO:0043269 215 0.158
melanin metabolic process GO:0006582 12 0.158
Mouse
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 2 0.158
Mouse
maintenance of location GO:0051235 89 0.157
cellular homeostasis GO:0019725 240 0.157
response to radiation GO:0009314 165 0.157
macromolecule catabolic process GO:0009057 281 0.157
nucleotide metabolic process GO:0009117 332 0.156
Worm
embryonic appendage morphogenesis GO:0035113 126 0.151
Mouse
neuron death GO:0070997 154 0.150
Mouse
apoptotic process involved in patterning of blood vessels GO:1902262 6 0.149
negative regulation of cellular protein metabolic process GO:0032269 247 0.148
cellular response to dna damage stimulus GO:0006974 207 0.148
glycosyl compound metabolic process GO:1901657 246 0.147
Worm
muscle fiber development GO:0048747 76 0.146
Mouse
positive regulation of protein modification process GO:0031401 299 0.146
Mouse
myotube differentiation GO:0014902 105 0.146
Mouse
regulation of mitochondrial membrane permeability GO:0046902 17 0.144
Mouse
germ cell development GO:0007281 185 0.143
Mouse
t cell proliferation GO:0042098 120 0.142
Mouse
forebrain development GO:0030900 302 0.141
Mouse
lymphocyte homeostasis GO:0002260 64 0.141
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.140
Mouse
regulation of smooth muscle cell migration GO:0014910 6 0.138
Mouse
response to light stimulus GO:0009416 135 0.137
dna catabolic process endonucleolytic GO:0000737 15 0.137
positive regulation of homeostatic process GO:0032846 64 0.137
guanosine containing compound metabolic process GO:1901068 144 0.133
Worm
b cell homeostasis GO:0001782 34 0.132
t cell differentiation in thymus GO:0033077 77 0.131
Mouse
positive regulation of response to oxidative stress GO:1902884 6 0.131
Mouse
appendage development GO:0048736 166 0.130
pallium development GO:0021543 120 0.130
Mouse
negative regulation of cell cycle GO:0045786 123 0.129
Mouse
response to oxidative stress GO:0006979 123 0.128
Mouse
response to organonitrogen compound GO:0010243 246 0.128
Mouse
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 34 0.128
Mouse
regulation of fibroblast proliferation GO:0048145 34 0.127
Mouse
response to cycloheximide GO:0046898 1 0.126
Mouse
positive regulation of cellular component biogenesis GO:0044089 94 0.126
positive regulation of apoptotic signaling pathway GO:2001235 95 0.125
Mouse
odontogenesis of dentin containing tooth GO:0042475 66 0.124
Mouse
release of sequestered calcium ion into cytosol GO:0051209 42 0.124
Mouse
positive regulation of intracellular transport GO:0032388 70 0.123
ear development GO:0043583 200 0.122
Mouse
cell adhesion GO:0007155 329 0.122
Mouse
sequestering of metal ion GO:0051238 19 0.122
organelle fission GO:0048285 170 0.119
regulation of mitochondrial membrane permeability involved in programmed necrotic cell death GO:1902445 2 0.118
Mouse
positive regulation of cell death GO:0010942 224 0.117
regulation of cell migration GO:0030334 219 0.117
Mouse
regulation of protein oligomerization GO:0032459 4 0.116
appendage morphogenesis GO:0035107 149 0.115
regulation of peptidyl serine phosphorylation GO:0033135 39 0.115
intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 35 0.114
Mouse
negative regulation of cell proliferation GO:0008285 296 0.114
Mouse
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.113
Mouse
ossification GO:0001503 216 0.113
Mouse
regulation of cell activation GO:0050865 289 0.112
cellular response to amino acid stimulus GO:0071230 29 0.111
Mouse
sphingolipid metabolic process GO:0006665 45 0.111
Mouse
aromatic compound catabolic process GO:0019439 286 0.110
Worm
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001241 10 0.110
Mouse
morphogenesis of a branching structure GO:0001763 203 0.109
t cell homeostasis GO:0043029 35 0.109
Mouse
gtp metabolic process GO:0046039 144 0.108
Worm
regulation of mitotic cell cycle phase transition GO:1901990 73 0.106
Mouse
regulation of cell adhesion GO:0030155 154 0.106
Mouse
striated muscle cell development GO:0055002 125 0.105
Mouse
epidermis development GO:0008544 187 0.104
Mouse
multicellular organism growth GO:0035264 161 0.104
Mouse
cellular response to glucose starvation GO:0042149 5 0.103
Mouse
secondary metabolic process GO:0019748 18 0.103
Mouse
myeloid cell apoptotic process GO:0033028 22 0.102
Mouse
glial cell apoptotic process GO:0034349 3 0.102
regulation of myotube differentiation GO:0010830 62 0.102
Mouse
cellular macromolecule catabolic process GO:0044265 206 0.100
homeostasis of number of cells within a tissue GO:0048873 25 0.099
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.099
Worm
regulation of cellular response to oxidative stress GO:1900407 19 0.099
Mouse
positive regulation of gtpase activity GO:0043547 85 0.099
Worm
glycolipid metabolic process GO:0006664 25 0.098
Mouse
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 57 0.097
regulation of protein complex assembly GO:0043254 83 0.097
viral life cycle GO:0019058 36 0.097
Mouse
regulation of neuron death GO:1901214 134 0.096
Mouse
modification by symbiont of host morphology or physiology GO:0044003 4 0.095
microtubule based process GO:0007017 236 0.095
cellular metal ion homeostasis GO:0006875 151 0.095
male gamete generation GO:0048232 285 0.094
Mouse
phenol containing compound metabolic process GO:0018958 60 0.094
Mouse
male gonad development GO:0008584 88 0.093
Mouse
negative regulation of growth GO:0045926 99 0.093
Mouse
mesenchymal cell development GO:0014031 93 0.093
Mouse
liposaccharide metabolic process GO:1903509 27 0.093
Mouse
lymphocyte differentiation GO:0030098 242 0.092
skeletal muscle organ development GO:0060538 163 0.092
Mouse
ovarian follicle development GO:0001541 40 0.092
Mouse
response to reactive oxygen species GO:0000302 56 0.092
Mouse
covalent chromatin modification GO:0016569 163 0.091
tissue homeostasis GO:0001894 115 0.091
Mouse
negative regulation of protein modification process GO:0031400 163 0.091
alpha beta t cell activation GO:0046631 91 0.090
Mouse
regulation of protein heterodimerization activity GO:0043497 2 0.090
g1 s transition of mitotic cell cycle GO:0000082 57 0.090
Mouse
alpha beta t cell differentiation GO:0046632 69 0.090
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 226 0.090
Worm
negative regulation of lymphocyte apoptotic process GO:0070229 24 0.090
Mouse
nucleoside triphosphate catabolic process GO:0009143 205 0.088
Worm
epithelial tube morphogenesis GO:0060562 303 0.088
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.087
pigment metabolic process GO:0042440 32 0.087
Mouse
regulation of ion homeostasis GO:2000021 64 0.087
cellular amine metabolic process GO:0044106 44 0.086
pigmentation GO:0043473 71 0.086
Mouse
regulation of proteolysis GO:0030162 164 0.086
negative regulation of molecular function GO:0044092 258 0.086
viral genome replication GO:0019079 17 0.086
Mouse
negative regulation of neuron apoptotic process GO:0043524 92 0.085
Mouse
negative regulation of phosphorylation GO:0042326 166 0.085
pigment cell differentiation GO:0050931 27 0.085
Mouse
purine ribonucleoside catabolic process GO:0046130 205 0.085
Worm
regulation of apoptotic signaling pathway GO:2001233 197 0.085
Mouse
blood vessel morphogenesis GO:0048514 285 0.084
calcium ion transport into cytosol GO:0060402 48 0.084
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 34 0.084
Mouse
establishment of protein localization to organelle GO:0072594 118 0.083
Mouse
leukocyte homeostasis GO:0001776 79 0.083
thymus development GO:0048538 41 0.083
Mouse
positive regulation of peptidase activity GO:0010952 49 0.083
mitotic cell cycle GO:0000278 195 0.082
Mouse
regulation of cell motility GO:2000145 236 0.082
Mouse
organophosphate catabolic process GO:0046434 232 0.081
Worm
regulation of response to oxidative stress GO:1902882 19 0.081
Mouse
positive regulation of cell motility GO:2000147 116 0.080
Mouse
regulation of g1 s transition of mitotic cell cycle GO:2000045 35 0.080
Mouse
gtp catabolic process GO:0006184 143 0.080
Worm
embryonic digit morphogenesis GO:0042733 56 0.079
Mouse
gland development GO:0048732 330 0.079
Mouse
cellular response to light stimulus GO:0071482 19 0.079
cellular nitrogen compound catabolic process GO:0044270 280 0.078
Worm
glycosyl compound catabolic process GO:1901658 206 0.078
Worm
limb development GO:0060173 166 0.078
extrinsic apoptotic signaling pathway GO:0097191 126 0.078
b cell differentiation GO:0030183 78 0.077
regulation of cell substrate adhesion GO:0010810 73 0.076
Mouse
mammary gland epithelial cell proliferation GO:0033598 24 0.075
Mouse
purine ribonucleotide catabolic process GO:0009154 208 0.075
Worm
ribonucleotide catabolic process GO:0009261 208 0.074
Worm
pons development GO:0021548 13 0.074
Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.074
Mouse
cellular response to abiotic stimulus GO:0071214 56 0.073
positive regulation of ion transport GO:0043270 65 0.073
response to uv GO:0009411 44 0.073
mammary gland morphogenesis GO:0060443 54 0.072
Mouse
cellular response to virus GO:0098586 7 0.071
Mouse
response to hypoxia GO:0001666 58 0.071
Mouse
regulation of metal ion transport GO:0010959 106 0.071
negative regulation of cellular amine metabolic process GO:0033239 1 0.071
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.071
Worm
spleen development GO:0048536 39 0.071
Mouse
smooth muscle cell migration GO:0014909 10 0.070
Mouse
regulation of striated muscle cell differentiation GO:0051153 81 0.070
Mouse
developmental programmed cell death GO:0010623 41 0.070
cell junction organization GO:0034330 77 0.070
Mouse
response to inorganic substance GO:0010035 96 0.069
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.069
Mouse
regulation of cellular catabolic process GO:0031329 242 0.069
Worm
positive regulation of calcium ion transport GO:0051928 27 0.069
purine containing compound metabolic process GO:0072521 311 0.068
Worm
negative regulation of cell development GO:0010721 169 0.068
Mouse
chromatin organization GO:0006325 206 0.068
regulation of muscle tissue development GO:1901861 97 0.068
Mouse
regulation of osteoblast proliferation GO:0033688 15 0.068
Mouse
ribonucleoside catabolic process GO:0042454 206 0.067
Worm
regulation of cellular component biogenesis GO:0044087 181 0.067
neuroepithelial cell differentiation GO:0060563 37 0.067
Mouse
regulation of protein homodimerization activity GO:0043496 4 0.067
odontogenesis GO:0042476 78 0.066
Mouse
regulation of glycoprotein biosynthetic process GO:0010559 12 0.066
Mouse
regulation of leukocyte proliferation GO:0070663 121 0.066
mitotic cell cycle process GO:1903047 159 0.065
Mouse
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.065
Mouse
retinal cell programmed cell death GO:0046666 8 0.065
Mouse
immune effector process GO:0002252 321 0.065
spermatogenesis GO:0007283 284 0.064
Mouse
stem cell development GO:0048864 219 0.064
Mouse
t cell apoptotic process GO:0070231 39 0.064
myeloid cell homeostasis GO:0002262 114 0.064
regulation of purine nucleotide metabolic process GO:1900542 169 0.064
Worm
positive regulation of protein complex assembly GO:0031334 45 0.064
thymocyte apoptotic process GO:0070242 19 0.064
reactive oxygen species metabolic process GO:0072593 84 0.063
Mouse
hematopoietic progenitor cell differentiation GO:0002244 143 0.063
Mouse
rhythmic process GO:0048511 174 0.063
Mouse
female sex differentiation GO:0046660 84 0.062
negative regulation of b cell apoptotic process GO:0002903 7 0.062
Mouse
nitrogen utilization GO:0019740 2 0.062
Mouse
leukocyte differentiation GO:0002521 342 0.062
purine ribonucleotide metabolic process GO:0009150 290 0.062
Worm
positive regulation of tissue remodeling GO:0034105 19 0.062
Mouse
retina development in camera type eye GO:0060041 119 0.062
Mouse
positive regulation of programmed cell death GO:0043068 218 0.062
cytosolic calcium ion transport GO:0060401 48 0.062
protein homooligomerization GO:0051260 43 0.062
Mouse
apoptotic process involved in development GO:1902742 28 0.061
cell substrate adhesion GO:0031589 130 0.061
Mouse
purine ribonucleoside metabolic process GO:0046128 241 0.061
Worm
cellular response to ionizing radiation GO:0071479 11 0.061
Mouse
negative regulation of cell cycle g1 s phase transition GO:1902807 18 0.061
Mouse
myosin filament assembly GO:0031034 2 0.060
negative regulation of fibroblast proliferation GO:0048147 14 0.060
Mouse
regulation of skeletal muscle fiber development GO:0048742 36 0.060
Mouse
methylation GO:0032259 134 0.059
developmental pigmentation GO:0048066 40 0.059
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.059
Worm
divalent inorganic cation transport GO:0072511 178 0.058
regulation of membrane potential GO:0042391 192 0.058
Mouse
blastocyst formation GO:0001825 33 0.058
adherens junction assembly GO:0034333 22 0.058
Mouse
response to mycotoxin GO:0010046 1 0.058
morphogenesis of a branching epithelium GO:0061138 193 0.058
establishment of organelle localization GO:0051656 122 0.058
development of primary female sexual characteristics GO:0046545 73 0.058
Mouse
homeostasis of number of cells GO:0048872 210 0.058
carbohydrate derivative catabolic process GO:1901136 231 0.057
Worm
t cell differentiation GO:0030217 174 0.057
Mouse
negative regulation of homeostatic process GO:0032845 71 0.056
Mouse
regulation of apoptotic dna fragmentation GO:1902510 5 0.056
sequestering of calcium ion GO:0051208 18 0.056
divalent inorganic cation homeostasis GO:0072507 138 0.055
regulation of cysteine type endopeptidase activity GO:2000116 65 0.055
neuron migration GO:0001764 122 0.055
Mouse
calcium ion homeostasis GO:0055074 127 0.055
nephron development GO:0072006 109 0.055
Mouse
protein maturation GO:0051604 176 0.055
small gtpase mediated signal transduction GO:0007264 97 0.054
divalent metal ion transport GO:0070838 172 0.054
positive regulation of nervous system development GO:0051962 221 0.053
Mouse
regulation of cell cycle g1 s phase transition GO:1902806 35 0.053
Mouse
cd8 positive alpha beta t cell activation GO:0036037 9 0.053
Mouse
mammary gland epithelium development GO:0061180 65 0.053
Mouse
response to organic cyclic compound GO:0014070 198 0.052
Mouse
ribonucleotide metabolic process GO:0009259 291 0.052
Worm
myeloid cell differentiation GO:0030099 233 0.052
development of primary sexual characteristics GO:0045137 143 0.052
Mouse
regulation of protein kinase activity GO:0045859 232 0.051
organic cyclic compound catabolic process GO:1901361 295 0.051
Worm
blastocyst development GO:0001824 80 0.051
dna metabolic process GO:0006259 303 0.050
nucleoside phosphate metabolic process GO:0006753 338 0.050
Worm
fertilization GO:0009566 127 0.050
Mouse
positive regulation of neuron death GO:1901216 28 0.049
Mouse
hindbrain development GO:0030902 128 0.049
Mouse
muscle cell migration GO:0014812 19 0.049
Mouse
defense response to virus GO:0051607 68 0.049
myotube cell development GO:0014904 60 0.049
Mouse
nucleoside phosphate catabolic process GO:1901292 222 0.049
Worm
negative regulation of leukocyte apoptotic process GO:2000107 31 0.049
Mouse
regulation of binding GO:0051098 111 0.048
neural nucleus development GO:0048857 22 0.048
Mouse
cd8 positive alpha beta t cell differentiation GO:0043374 9 0.048
Mouse
mitochondrial outer membrane permeabilization GO:0097345 10 0.048
Mouse
signal transduction by p53 class mediator GO:0072331 51 0.048
Mouse
purine nucleotide metabolic process GO:0006163 302 0.048
Worm
signal transduction in absence of ligand GO:0038034 55 0.048
protein localization to mitochondrion GO:0070585 15 0.048
Mouse
mesonephric tubule development GO:0072164 94 0.047
Mouse
er nucleus signaling pathway GO:0006984 27 0.047
positive regulation of peptidyl serine phosphorylation GO:0033138 25 0.047
Mouse
axon regeneration GO:0031103 12 0.047
Mouse
digestive tract morphogenesis GO:0048546 147 0.047
Mouse
hepatocyte apoptotic process GO:0097284 11 0.047
Mouse
protein methylation GO:0006479 81 0.046
positive regulation of gtp catabolic process GO:0033126 85 0.046
Worm
cell fate commitment GO:0045165 210 0.046
Mouse
gonad development GO:0008406 141 0.046
Mouse
endomembrane system organization GO:0010256 147 0.046
regulation of intracellular transport GO:0032386 159 0.046
chromatin modification GO:0016568 187 0.045
ribonucleoside triphosphate metabolic process GO:0009199 220 0.045
Worm
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.045
dephosphorylation GO:0016311 129 0.045
Mouse
cellular calcium ion homeostasis GO:0006874 119 0.045
mesenchymal cell differentiation GO:0048762 107 0.045
Mouse
positive regulation of cell migration GO:0030335 109 0.045
Mouse
negative regulation of cytoplasmic transport GO:1903650 29 0.045
Mouse
regulation of nucleotide metabolic process GO:0006140 169 0.044
Worm
oocyte differentiation GO:0009994 35 0.044
Mouse
focal adhesion assembly GO:0048041 19 0.044
Mouse
regulation of transferase activity GO:0051338 263 0.044
positive regulation of striated muscle tissue development GO:0045844 31 0.044
Mouse
defense response to other organism GO:0098542 197 0.044
skin morphogenesis GO:0043589 38 0.044
Mouse
regulation of mitotic cell cycle GO:0007346 126 0.044
Mouse
apoptotic nuclear changes GO:0030262 9 0.043
genitalia development GO:0048806 37 0.043
organonitrogen compound catabolic process GO:1901565 264 0.043
Worm
glycoprotein metabolic process GO:0009100 116 0.043
Mouse
regulation of protein binding GO:0043393 60 0.042
apoptotic dna fragmentation GO:0006309 7 0.042
cell maturation GO:0048469 127 0.042
Mouse
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.042
ovulation cycle GO:0042698 59 0.042
Mouse
second messenger mediated signaling GO:0019932 73 0.042
vagina development GO:0060068 11 0.042
regulation of gtp catabolic process GO:0033124 113 0.042
Worm
organ growth GO:0035265 117 0.042
Mouse
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 27 0.041
axonogenesis GO:0007409 274 0.041
Mouse
melanocyte differentiation GO:0030318 25 0.041
Mouse
nucleoside triphosphate metabolic process GO:0009141 230 0.041
Worm
protein oligomerization GO:0051259 67 0.041
Mouse
translation GO:0006412 93 0.041
hair follicle morphogenesis GO:0031069 29 0.041
Mouse
mapk cascade GO:0000165 281 0.041
compound eye development GO:0048749 1 0.041
establishment of protein localization to mitochondrion GO:0072655 11 0.041
Mouse
cell substrate adherens junction assembly GO:0007045 19 0.041
Mouse
regulation of lymphocyte activation GO:0051249 240 0.040
development of secondary sexual characteristics GO:0045136 11 0.040
Mouse
cellular response to oxidative stress GO:0034599 76 0.040
Mouse
positive regulation of neuron differentiation GO:0045666 141 0.040
Mouse
regulation of cytoplasmic transport GO:1903649 112 0.039
locomotory behavior GO:0007626 195 0.039
inflammatory response GO:0006954 244 0.039
adherens junction organization GO:0034332 28 0.039
Mouse
purine nucleoside triphosphate catabolic process GO:0009146 203 0.039
Worm
cellular response to radiation GO:0071478 28 0.039
response to unfolded protein GO:0006986 21 0.039

Bak1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.435
disease of cellular proliferation DOID:14566 0 0.435
immune system cancer DOID:0060083 0 0.315
organ system cancer DOID:0050686 0 0.315
hematologic cancer DOID:2531 0 0.196
leukemia DOID:1240 0 0.191
gastrointestinal system cancer DOID:3119 0 0.150
colon carcinoma DOID:1520 0 0.117
large intestine cancer DOID:5672 0 0.117
colon cancer DOID:219 0 0.117
intestinal cancer DOID:10155 0 0.117
colorectal cancer DOID:9256 0 0.117
disease of anatomical entity DOID:7 0 0.073
musculoskeletal system disease DOID:17 0 0.073