IMP
Process View
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway
Any process that initiates the activity of an inactive cysteine-type endopeptidase involved in the apoptotic signaling pathway.
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Click on a gene's description to view its network relationships with genes known to be involved in "activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 1.000 | ||
| Trp53 | transformation related protein 53 | 1.000 | ||
| Bax | BCL2-associated X protein | 1.000 | ||
| Kit | kit oncogene | 0.997 | ||
| Bcl2 | B-cell leukemia/lymphoma 2 | 0.988 | Mouse | |
| Pten | phosphatase and tensin homolog | 0.973 | ||
| Vhl | von Hippel-Lindau tumor suppressor | 0.963 | ||
| Apc | adenomatosis polyposis coli | 0.959 | ||
| Foxp3 | forkhead box P3 | 0.949 | ||
| Stat3 | signal transducer and activator of transcription 3 | 0.942 | ||
| Tgfb1 | transforming growth factor, beta 1 | 0.873 | ||
| Il6st | interleukin 6 signal transducer | 0.765 | ||
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.733 | ||
| Fas | Fas (TNF receptor superfamily member 6) | 0.645 | ||
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.626 | ||
| Ikzf1 | IKAROS family zinc finger 1 | 0.601 | ||
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.587 | ||
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.584 | ||
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.573 | ||
| Rxra | retinoid X receptor alpha | 0.555 | ||
| Socs1 | suppressor of cytokine signaling 1 | 0.495 | ||
| Lyst | lysosomal trafficking regulator | 0.463 | ||
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.430 | ||
| Lepr | leptin receptor | 0.379 | ||
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.283 | ||
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.274 | ||
| Smad4 | MAD homolog 4 (Drosophila) | 0.270 | ||
| Ncoa3 | nuclear receptor coactivator 3 | 0.197 | ||
| Vdr | vitamin D receptor | 0.193 | ||
| Dicer1 | Dicer1, Dcr-1 homolog (Drosophila) | 0.190 | ||
| Crim1 | cysteine rich transmembrane BMP regulator 1 (chordin like) | 0.184 | ||
| Esr1 | estrogen receptor 1 (alpha) | 0.174 | ||
| Igh | immunoglobulin heavy chain complex | 0.164 | ||
| Braf | Braf transforming gene | 0.162 | ||
| Bak1 | BCL2-antagonist/killer 1 | 0.158 | Mouse | |
| Tcra | T-cell receptor alpha chain | 0.153 | ||
| Il2rg | interleukin 2 receptor, gamma chain | 0.153 | ||
| Tnfaip3 | tumor necrosis factor, alpha-induced protein 3 | 0.151 | ||
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.123 | ||
| Pmaip1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.116 | ||
| Socs3 | suppressor of cytokine signaling 3 | 0.101 | ||
| Ptprc | protein tyrosine phosphatase, receptor type, C | 0.100 | ||
| Stat5a | signal transducer and activator of transcription 5A | 0.098 | ||
| Mfn2 | mitofusin 2 | 0.095 | ||
| Smad3 | MAD homolog 3 (Drosophila) | 0.091 | Rat | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.089 | ||
| Rara | retinoic acid receptor, alpha | 0.086 | ||
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.085 | ||
| Tnf | tumor necrosis factor | 0.079 | ||
| Fgfr1 | fibroblast growth factor receptor 1 | 0.069 | ||
| Ret | ret proto-oncogene | 0.068 | ||
| Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 | 0.067 | ||
| Pkd1 | polycystic kidney disease 1 homolog | 0.065 | ||
| Btg1 | B-cell translocation gene 1, anti-proliferative | 0.063 | ||
| Adam17 | a disintegrin and metallopeptidase domain 17 | 0.058 | ||
| Stat5b | signal transducer and activator of transcription 5B | 0.055 | ||
| Vegfa | vascular endothelial growth factor A | 0.054 | ||
| Kitl | kit ligand | 0.053 | ||
| Relb | avian reticuloendotheliosis viral (v-rel) oncogene related B | 0.050 | ||
| Lyz2 | lysozyme 2 | 0.048 | ||
| Pax2 | paired box gene 2 | 0.046 | ||
| Cd19 | CD19 antigen | 0.045 | ||
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.043 | ||
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.043 | ||
| Wt1 | Wilms tumor 1 homolog | 0.042 | ||
| Nfkbia | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.042 | ||
| Tnip1 | TNFAIP3 interacting protein 1 | 0.041 | ||
| Cd44 | CD44 antigen | 0.041 | ||
| Col1a1 | collagen, type I, alpha 1 | 0.041 | ||
| Pparg | peroxisome proliferator activated receptor gamma | 0.041 | ||
| Csf1 | colony stimulating factor 1 (macrophage) | 0.039 | ||
| Bcl2l1 | BCL2-like 1 | 0.039 | Mouse | |
| Prkci | protein kinase C, iota | 0.035 | ||
| Axin1 | axin 1 | 0.035 | ||
| Ifng | interferon gamma | 0.034 | ||
| Runx1 | runt related transcription factor 1 | 0.034 | ||
| Ptpn22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.033 | ||
| Ikzf3 | IKAROS family zinc finger 3 | 0.033 | ||
| Inpp5d | inositol polyphosphate-5-phosphatase D | 0.033 | ||
| Tcrd | T-cell receptor delta chain | 0.032 | ||
| Smad2 | MAD homolog 2 (Drosophila) | 0.028 | ||
| Mtor | mechanistic target of rapamycin (serine/threonine kinase) | 0.028 | ||
| Ar | androgen receptor | 0.028 | ||
| Sh2b1 | SH2B adaptor protein 1 | 0.027 | ||
| Tcrb | T-cell receptor beta chain | 0.026 | ||
| Hif1a | hypoxia inducible factor 1, alpha subunit | 0.026 | ||
| Dok1 | docking protein 1 | 0.026 | ||
| Nfe2l2 | nuclear factor, erythroid derived 2, like 2 | 0.025 | ||
| Prkdc | protein kinase, DNA activated, catalytic polypeptide | 0.025 | ||
| Ids | iduronate 2-sulfatase | 0.024 | ||
| Vav2 | vav 2 oncogene | 0.024 | ||
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.024 | ||
| Skil | SKI-like | 0.024 | ||
| Mdm4 | transformed mouse 3T3 cell double minute 4 | 0.023 | ||
| Ifnar1 | interferon (alpha and beta) receptor 1 | 0.022 | ||
| Cyld | cylindromatosis (turban tumor syndrome) | 0.021 | ||
| Rarg | retinoic acid receptor, gamma | 0.020 | ||
| Ifngr1 | interferon gamma receptor 1 | 0.020 | ||
| Jak2 | Janus kinase 2 | 0.020 | ||
| Gna13 | guanine nucleotide binding protein, alpha 13 | 0.019 | ||
| Elf1 | E74-like factor 1 | 0.019 | ||
| Irf1 | interferon regulatory factor 1 | 0.018 | ||
| Stk11 | serine/threonine kinase 11 | 0.018 | ||
| Polr2a | polymerase (RNA) II (DNA directed) polypeptide A | 0.018 | ||
| Lyn | Yamaguchi sarcoma viral (v-yes-1) oncogene homolog | 0.018 | ||
| Lgr4 | leucine-rich repeat-containing G protein-coupled receptor 4 | 0.018 | ||
| Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.017 | ||
| Rag1 | recombination activating gene 1 | 0.017 | ||
| Ifngr2 | interferon gamma receptor 2 | 0.017 | ||
| Rela | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.017 | ||
| Nf1 | neurofibromatosis 1 | 0.017 | ||
| Cbl | Casitas B-lineage lymphoma | 0.017 | ||
| Rb1 | retinoblastoma 1 | 0.016 | ||
| Rasal3 | RAS protein activator like 3 | 0.016 | ||
| Pxn | paxillin | 0.016 | ||
| Thbs1 | thrombospondin 1 | 0.016 | ||
| Bid | BH3 interacting domain death agonist | 0.015 | ||
| Sh2b3 | SH2B adaptor protein 3 | 0.015 | ||
| Irf8 | interferon regulatory factor 8 | 0.015 | ||
| Notch1 | Notch gene homolog 1 (Drosophila) | 0.015 | ||
| Stat6 | signal transducer and activator of transcription 6 | 0.015 | ||
| Lama5 | laminin, alpha 5 | 0.015 | ||
| Ehd3 | EH-domain containing 3 | 0.015 | ||
| Map3k14 | mitogen-activated protein kinase kinase kinase 14 | 0.015 | ||
| Hdac7 | histone deacetylase 7 | 0.015 | ||
| Pik3cd | phosphatidylinositol 3-kinase catalytic delta polypeptide | 0.015 | ||
| Apoe | apolipoprotein E | 0.015 | ||
| Prkcd | protein kinase C, delta | 0.014 | ||
| Ets1 | E26 avian leukemia oncogene 1, 5' domain | 0.014 | ||
| Psen1 | presenilin 1 | 0.014 | ||
| Socs5 | suppressor of cytokine signaling 5 | 0.013 | ||
| Lck | lymphocyte protein tyrosine kinase | 0.013 | ||
| Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | 0.013 | ||
| Huwe1 | HECT, UBA and WWE domain containing 1 | 0.013 | ||
| Elavl1 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) | 0.013 | ||
| Ikbkb | inhibitor of kappaB kinase beta | 0.013 | ||
| Tgfbr2 | transforming growth factor, beta receptor II | 0.013 | ||
| Vav1 | vav 1 oncogene | 0.013 | ||
| Klf6 | Kruppel-like factor 6 | 0.013 | ||
| Ugcg | UDP-glucose ceramide glucosyltransferase | 0.013 | ||
| Ctnnd1 | catenin (cadherin associated protein), delta 1 | 0.013 | ||
| Pim1 | proviral integration site 1 | 0.013 | ||
| Kif3b | kinesin family member 3B | 0.012 | ||
| Smad5 | MAD homolog 5 (Drosophila) | 0.012 | ||
| Mcl1 | myeloid cell leukemia sequence 1 | 0.012 | Mouse | |
| Rap2c | RAP2C, member of RAS oncogene family | 0.012 | ||
| Ncoa2 | nuclear receptor coactivator 2 | 0.012 | ||
| Bcl3 | B-cell leukemia/lymphoma 3 | 0.012 | ||
| Dnm2 | dynamin 2 | 0.011 | ||
| Epor | erythropoietin receptor | 0.011 | ||
| Capn1 | calpain 1 | 0.011 | ||
| Plekho2 | pleckstrin homology domain containing, family O member 2 | 0.011 | ||
| Ptch1 | patched homolog 1 | 0.011 | ||
| Gnaq | guanine nucleotide binding protein, alpha q polypeptide | 0.011 | ||
| Fmnl1 | formin-like 1 | 0.011 | ||
| Meox2 | mesenchyme homeobox 2 | 0.010 | ||
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.010 | ||
| Rrm2b | ribonucleotide reductase M2 B (TP53 inducible) | 0.010 | ||
| S1pr4 | sphingosine-1-phosphate receptor 4 | 0.010 |