Mus musculus

219 known processes

Cenpe

centromere protein E

(Aliases: 312kDa,C530022J18,AU019344,Kif10,CENP-E,BC049989)

Cenpe biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
male meiosis GO:0007140 37 0.766
organelle fission GO:0048285 170 0.655
microtubule cytoskeleton organization GO:0000226 157 0.643
mitotic cell cycle GO:0000278 195 0.617
nuclear division GO:0000280 158 0.616
microtubule based process GO:0007017 236 0.587
chromosome segregation GO:0007059 48 0.475
meiotic cell cycle process GO:1903046 77 0.430
mitotic sister chromatid segregation GO:0000070 14 0.393
spindle assembly involved in mitosis GO:0090307 4 0.357
regulation of chromosome segregation GO:0051983 21 0.355
cellular macromolecule catabolic process GO:0044265 206 0.346
meiotic cell cycle GO:0051321 122 0.337
metaphase anaphase transition of mitotic cell cycle GO:0007091 9 0.327
mitotic spindle assembly checkpoint GO:0007094 7 0.303
regulation of cell cycle process GO:0010564 160 0.298
regulation of microtubule based process GO:0032886 52 0.286
negative regulation of nuclear division GO:0051784 19 0.247
mitotic cell cycle process GO:1903047 159 0.232
meiotic chromosome segregation GO:0045132 19 0.224
sister chromatid segregation GO:0000819 20 0.215
regulation of metaphase anaphase transition of cell cycle GO:1902099 9 0.215
meiosis ii GO:0007135 7 0.213
regulation of sister chromatid segregation GO:0033045 13 0.196
ubiquitin dependent protein catabolic process GO:0006511 129 0.190
regulation of organelle organization GO:0033043 289 0.181
mitotic sister chromatid separation GO:0051306 9 0.174
meiotic nuclear division GO:0007126 115 0.170
mitotic spindle checkpoint GO:0071174 9 0.158
negative regulation of cell cycle process GO:0010948 69 0.156
negative regulation of cellular component organization GO:0051129 194 0.154
dna repair GO:0006281 107 0.154
cellular protein catabolic process GO:0044257 155 0.145
regulation of exit from mitosis GO:0007096 1 0.141
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 15 0.136
male gamete generation GO:0048232 285 0.130
cellular response to dna damage stimulus GO:0006974 207 0.123
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.118
dna metabolic process GO:0006259 303 0.118
regulation of cell division GO:0051302 76 0.116
protein catabolic process GO:0030163 221 0.112
macromolecule catabolic process GO:0009057 281 0.110
regulation of protein catabolic process GO:0042176 108 0.109
negative regulation of cell cycle phase transition GO:1901988 48 0.107
regulation of mitotic cell cycle phase transition GO:1901990 73 0.107
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 88 0.101
negative regulation of sister chromatid segregation GO:0033046 7 0.094
attachment of spindle microtubules to kinetochore GO:0008608 4 0.091
organelle assembly GO:0070925 177 0.090
spindle assembly GO:0051225 13 0.089
germ cell development GO:0007281 185 0.089
spindle checkpoint GO:0031577 12 0.089
female meiotic division GO:0007143 21 0.088
female meiosis chromosome segregation GO:0016321 1 0.088
regulation of cell cycle GO:0051726 281 0.087
mitotic sister chromatid cohesion GO:0007064 1 0.086
negative regulation of organelle organization GO:0010639 90 0.085
maintenance of location GO:0051235 89 0.084
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 56 0.082
microtubule organizing center organization GO:0031023 28 0.082
regulation of mitosis GO:0007088 29 0.082
chromosome organization involved in meiosis GO:0070192 39 0.078
cell cycle comprising mitosis without cytokinesis GO:0033301 1 0.078
lateral inhibition GO:0046331 1 0.075
regulation of microtubule cytoskeleton organization GO:0070507 37 0.075
microtubule cytoskeleton organization involved in mitosis GO:1902850 4 0.072
regulation of cellular protein catabolic process GO:1903362 61 0.070
negative regulation of cell division GO:0051782 24 0.069
mitotic nuclear division GO:0007067 48 0.069
cell division GO:0051301 120 0.068
positive regulation of mitotic metaphase anaphase transition GO:0045842 2 0.068
organelle localization GO:0051640 179 0.065
negative regulation of proteolysis GO:0045861 74 0.064
protein maturation GO:0051604 176 0.062
regulation of chromosome organization GO:0033044 83 0.060
cellular protein complex disassembly GO:0043624 36 0.059
microtubule polymerization or depolymerization GO:0031109 26 0.058
stem cell differentiation GO:0048863 268 0.058
meiotic sister chromatid segregation GO:0045144 6 0.058
establishment of spindle localization GO:0051293 19 0.058
negative regulation of cellular protein metabolic process GO:0032269 247 0.057
regulation of cytoskeleton organization GO:0051493 122 0.056
cellular amino acid metabolic process GO:0006520 103 0.056
protein modification by small protein conjugation or removal GO:0070647 207 0.054
regulation of mitotic cell cycle GO:0007346 126 0.053
negative regulation of mitotic sister chromatid separation GO:2000816 7 0.052
negative regulation of mitotic cell cycle phase transition GO:1901991 45 0.052
protein modification by small protein conjugation GO:0032446 187 0.050
lymphocyte mediated immunity GO:0002449 139 0.050
regulation of cell cycle phase transition GO:1901987 77 0.050
centromeric sister chromatid cohesion GO:0070601 3 0.050
negative regulation of protein processing GO:0010955 79 0.049
positive regulation of chromosome segregation GO:0051984 4 0.048
sister chromatid cohesion GO:0007062 12 0.047
regulation of nuclear division GO:0051783 56 0.046
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.046
metaphase plate congression GO:0051310 2 0.046
spindle organization GO:0007051 28 0.045
regulation of chromatin silencing GO:0031935 2 0.045
spermatogenesis GO:0007283 284 0.045
meiosis i GO:0007127 60 0.044
positive regulation of protein phosphorylation GO:0001934 242 0.041
establishment of organelle localization GO:0051656 122 0.040
regulation of proteasomal protein catabolic process GO:0061136 46 0.040
cellular ketone metabolic process GO:0042180 84 0.039
development of primary sexual characteristics GO:0045137 143 0.039
protein localization to organelle GO:0033365 185 0.039
spindle localization GO:0051653 22 0.037
modification dependent macromolecule catabolic process GO:0043632 133 0.037
negative regulation of cellular protein catabolic process GO:1903363 22 0.037
regulation of protein processing GO:0070613 96 0.036
regulation of transferase activity GO:0051338 263 0.036
regulation of protein complex disassembly GO:0043244 28 0.036
chromosome separation GO:0051304 14 0.035
cytokinetic process GO:0032506 2 0.035
establishment of meiotic spindle orientation GO:0051296 1 0.033
regulation of cellular amine metabolic process GO:0033238 20 0.033
regulation of proteolysis GO:0030162 164 0.033
centrosome duplication GO:0051298 16 0.032
amine metabolic process GO:0009308 45 0.032
negative regulation of cell cycle GO:0045786 123 0.030
negative regulation of chromosome organization GO:2001251 30 0.030
synaptonemal complex organization GO:0070193 15 0.030
positive regulation of organelle organization GO:0010638 128 0.030
negative regulation of mitotic cell cycle GO:0045930 58 0.030
immune effector process GO:0002252 321 0.030
response to radiation GO:0009314 165 0.029
negative regulation of mitotic sister chromatid segregation GO:0033048 7 0.029
regulation of cellular ketone metabolic process GO:0010565 66 0.029
protein localization to chromosome centromeric region GO:0071459 1 0.028
microtubule anchoring GO:0034453 9 0.028
centriole assembly GO:0098534 6 0.027
regulation of cellular amino acid metabolic process GO:0006521 5 0.027
centrosome cycle GO:0007098 23 0.027
regulation of cellular catabolic process GO:0031329 242 0.026
organic cyclic compound catabolic process GO:1901361 295 0.026
dna recombination GO:0006310 92 0.026
negative regulation of protein metabolic process GO:0051248 282 0.026
regulation of t cell activation GO:0050863 170 0.026
mitotic spindle organization GO:0007052 10 0.026
establishment or maintenance of cell polarity GO:0007163 86 0.025
centrosome organization GO:0051297 26 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.025
cellularization GO:0007349 1 0.025
spindle assembly involved in meiosis GO:0090306 4 0.024
stem cell development GO:0048864 219 0.024
positive regulation of chromosome organization GO:2001252 33 0.024
developmental maturation GO:0021700 193 0.024
histone threonine phosphorylation GO:0035405 1 0.024
chromatin modification GO:0016568 187 0.024
negative regulation of protein depolymerization GO:1901880 21 0.023
protein polyubiquitination GO:0000209 33 0.023
maintenance of location in cell GO:0051651 24 0.023
membrane tubulation GO:0097320 4 0.023
positive regulation of kinase activity GO:0033674 155 0.023
double strand break repair GO:0006302 48 0.023
cell maturation GO:0048469 127 0.022
mitotic cell cycle checkpoint GO:0007093 31 0.022
response to ionizing radiation GO:0010212 42 0.022
endomembrane system organization GO:0010256 147 0.022
oogenesis GO:0048477 56 0.022
positive regulation of cellular amine metabolic process GO:0033240 5 0.021
positive regulation of protein kinase activity GO:0045860 144 0.021
negative regulation of microtubule polymerization or depolymerization GO:0031111 15 0.020
regulation of microtubule depolymerization GO:0031114 13 0.020
leukocyte mediated immunity GO:0002443 174 0.020
meiotic dna repair synthesis GO:0000711 4 0.020
establishment of mitotic spindle localization GO:0040001 12 0.020
cell cycle switching GO:0060184 1 0.020
regulation of neuron differentiation GO:0045664 281 0.019
endocytosis GO:0006897 168 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.019
cellular response to growth factor stimulus GO:0071363 197 0.019
asymmetric stem cell division GO:0098722 3 0.019
neural tube formation GO:0001841 108 0.019
negative regulation of mitosis GO:0045839 10 0.018
negative regulation of cellular catabolic process GO:0031330 47 0.018
posttranscriptional regulation of gene expression GO:0010608 155 0.018
muscle tissue development GO:0060537 308 0.018
nucleobase containing small molecule metabolic process GO:0055086 352 0.018
regulation of protein serine threonine kinase activity GO:0071900 157 0.017
regulation of lymphocyte activation GO:0051249 240 0.017
protein polymerization GO:0051258 57 0.017
regulation of protein localization GO:0032880 231 0.017
regulation of cell activation GO:0050865 289 0.017
cellular amine metabolic process GO:0044106 44 0.017
purine nucleotide metabolic process GO:0006163 302 0.017
histone modification GO:0016570 159 0.017
regulation of protein maturation GO:1903317 96 0.017
actin filament organization GO:0007015 113 0.017
gonad development GO:0008406 141 0.016
t cell activation GO:0042110 289 0.016
exit from mitosis GO:0010458 3 0.016
regulation of mitotic metaphase anaphase transition GO:0030071 8 0.016
negative regulation of protein catabolic process GO:0042177 36 0.016
anatomical structure homeostasis GO:0060249 145 0.016
stem cell maintenance GO:0019827 130 0.016
positive regulation of cell cycle GO:0045787 92 0.016
response to light stimulus GO:0009416 135 0.016
female gamete generation GO:0007292 74 0.016
positive regulation of protein modification process GO:0031401 299 0.015
purine nucleoside monophosphate metabolic process GO:0009126 81 0.015
regulation of homeostatic process GO:0032844 182 0.015
ribonucleoside triphosphate metabolic process GO:0009199 220 0.015
mitotic cytokinesis GO:0000281 4 0.015
protein ubiquitination GO:0016567 171 0.015
spindle assembly involved in female meiosis GO:0007056 3 0.015
carbohydrate derivative catabolic process GO:1901136 231 0.015
neuron migration GO:0001764 122 0.015
neural precursor cell proliferation GO:0061351 121 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.014
cell cycle checkpoint GO:0000075 47 0.014
purine nucleoside catabolic process GO:0006152 205 0.014
glycosyl compound metabolic process GO:1901657 246 0.014
regulation of microtubule polymerization or depolymerization GO:0031110 20 0.014
peptidyl amino acid modification GO:0018193 336 0.014
purine nucleoside metabolic process GO:0042278 241 0.014
membrane organization GO:0061024 245 0.014
cellular protein complex assembly GO:0043623 116 0.014
cell activation involved in immune response GO:0002263 126 0.014
microtubule sliding GO:0051012 1 0.014
nucleoside phosphate metabolic process GO:0006753 338 0.014
purine nucleoside triphosphate metabolic process GO:0009144 226 0.014
regulation of cell projection organization GO:0031344 206 0.014
response to uv GO:0009411 44 0.014
nucleoside triphosphate metabolic process GO:0009141 230 0.014
leukocyte activation involved in immune response GO:0002366 126 0.013
ribonucleotide metabolic process GO:0009259 291 0.013
glycosyl compound catabolic process GO:1901658 206 0.013
aromatic compound catabolic process GO:0019439 286 0.013
regulation of protein kinase activity GO:0045859 232 0.013
regulation of spindle organization GO:0090224 2 0.013
chromatin organization GO:0006325 206 0.013
response to growth factor GO:0070848 198 0.013
g1 s transition of mitotic cell cycle GO:0000082 57 0.013
intrinsic apoptotic signaling pathway GO:0097193 132 0.013
regulation of cellular component size GO:0032535 121 0.013
cell adhesion GO:0007155 329 0.013
regulation of neuron projection development GO:0010975 169 0.013
placenta development GO:0001890 140 0.013
ribose phosphate metabolic process GO:0019693 291 0.013
nucleotide metabolic process GO:0009117 332 0.013
microtubule depolymerization GO:0007019 15 0.013
innate immune response GO:0045087 157 0.013
macromolecule methylation GO:0043414 120 0.012
cellular response to organonitrogen compound GO:0071417 145 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.012
establishment of spindle orientation GO:0051294 15 0.012
response to organonitrogen compound GO:0010243 246 0.012
blastocyst development GO:0001824 80 0.012
purine nucleotide catabolic process GO:0006195 211 0.012
carbohydrate homeostasis GO:0033500 128 0.012
positive regulation of cellular catabolic process GO:0031331 148 0.012
rho protein signal transduction GO:0007266 32 0.012
negative regulation of cell development GO:0010721 169 0.012
translesion synthesis GO:0019985 1 0.012
cytokine production involved in immune response GO:0002367 34 0.012
regulation of response to wounding GO:1903034 189 0.012
rna processing GO:0006396 105 0.012
meiotic sister chromatid cohesion GO:0051177 6 0.012
regulation of leukocyte mediated immunity GO:0002703 104 0.012
covalent chromatin modification GO:0016569 163 0.012
purine containing compound metabolic process GO:0072521 311 0.011
positive regulation of nuclear division GO:0051785 27 0.011
intracellular mrna localization GO:0008298 4 0.011
purine ribonucleoside metabolic process GO:0046128 241 0.011
apoptotic signaling pathway GO:0097190 306 0.011
organism emergence from protective structure GO:0071684 4 0.011
negative regulation of protein complex disassembly GO:0043242 22 0.011
positive regulation of exit from mitosis GO:0031536 1 0.011
purine containing compound catabolic process GO:0072523 213 0.011
ossification GO:0001503 216 0.011
cellular lipid metabolic process GO:0044255 323 0.011
dna packaging GO:0006323 30 0.011
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.011
nucleoside metabolic process GO:0009116 246 0.010
muscle cell differentiation GO:0042692 261 0.010
ribonucleoside catabolic process GO:0042454 206 0.010
striated muscle tissue development GO:0014706 293 0.010
cell type specific apoptotic process GO:0097285 268 0.010
regulation of cytokine production GO:0001817 266 0.010
protein depolymerization GO:0051261 34 0.010
regulation of neural precursor cell proliferation GO:2000177 70 0.010
actin cytoskeleton organization GO:0030036 220 0.010
negative regulation of cell size GO:0045792 3 0.010
regulation of chromatin modification GO:1903308 57 0.010
positive regulation of mitosis GO:0045840 14 0.010
purine nucleoside triphosphate catabolic process GO:0009146 203 0.010
atp catabolic process GO:0006200 55 0.010
regulation of cellular component biogenesis GO:0044087 181 0.010
nucleoside catabolic process GO:0009164 206 0.010
regulation of cell projection assembly GO:0060491 38 0.010
blood vessel morphogenesis GO:0048514 285 0.010
regulation of kinase activity GO:0043549 249 0.010

Cenpe disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.459
disease of cellular proliferation DOID:14566 0 0.459
organ system cancer DOID:0050686 0 0.459
thoracic cancer DOID:5093 0 0.063
breast cancer DOID:1612 0 0.037
large intestine cancer DOID:5672 0 0.035
gastrointestinal system cancer DOID:3119 0 0.035
intestinal cancer DOID:10155 0 0.035
colon cancer DOID:219 0 0.035
colorectal cancer DOID:9256 0 0.035
immune system disease DOID:2914 0 0.027
disease of anatomical entity DOID:7 0 0.027
hematopoietic system disease DOID:74 0 0.027
colon carcinoma DOID:1520 0 0.019
physical disorder DOID:0080015 0 0.014
congenital nervous system abnormality DOID:2490 0 0.014