IMP

Process View

Mus musculus

15 genes annotated in mouse

synaptonemal complex organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synaptonemal complex. A synaptonemal complex is a proteinaceous scaffold formed between homologous chromosomes during meiosis.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "synaptonemal complex organization"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "synaptonemal complex organization" (in gray)

Name	Description	Probability	Func Analog Organism
Ccna2	cyclin A2	0.966
Cdc20	cell division cycle 20 homolog (S. cerevisiae)	0.871
Ccnb1	cyclin B1	0.781
Smc1a	structural maintenance of chromosomes 1A	0.755
Ccne1	cyclin E1	0.557
Ccnb2	cyclin B2	0.430
Mecp2	methyl CpG binding protein 2	0.353
Ckap2	cytoskeleton associated protein 2	0.274
Cdk1	cyclin-dependent kinase 1	0.272	Yeast
Kif20a	kinesin family member 20A	0.271
Neurl1a	neuralized homolog 1A (Drosophila)	0.221
Asf1b	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	0.187
Nuf2	NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)	0.184
Kif22	kinesin family member 22	0.173
Atp6v1d	ATPase, H+ transporting, lysosomal V1 subunit D	0.161
Birc5	baculoviral IAP repeat-containing 5	0.148
Cdca8	cell division cycle associated 8	0.128
D2Ertd750e	DNA segment, Chr 2, ERATO Doi 750, expressed	0.125
Cdc25c	cell division cycle 25 homolog C (S. pombe)	0.116
Uhrf1	ubiquitin-like, containing PHD and RING finger domains, 1	0.102
Tacc3	transforming, acidic coiled-coil containing protein 3	0.094
Cript	cysteine-rich PDZ-binding protein	0.094
Nxf2	nuclear RNA export factor 2	0.081
Aurkb	aurora kinase B	0.080
Kif23	kinesin family member 23	0.078
Pcna	proliferating cell nuclear antigen	0.076
Cdk2	cyclin-dependent kinase 2	0.070	Yeast
Rab5a	RAB5A, member RAS oncogene family	0.068
Ndfip1	Nedd4 family interacting protein 1	0.067
H2afx	H2A histone family, member X	0.067
Dnajb9	DnaJ (Hsp40) homolog, subfamily B, member 9	0.064
Ints9	integrator complex subunit 9	0.058
Csnk1g2	casein kinase 1, gamma 2	0.056
Racgap1	Rac GTPase-activating protein 1	0.051
Aurka	aurora kinase A	0.050
Rnf11	ring finger protein 11	0.050
Gnb2	guanine nucleotide binding protein (G protein), beta 2	0.050
Zfand5	zinc finger, AN1-type domain 5	0.049
Cpeb4	cytoplasmic polyadenylation element binding protein 4	0.047	Mouse
Usp21	ubiquitin specific peptidase 21	0.047
Cdca5	cell division cycle associated 5	0.046
Spag5	sperm associated antigen 5	0.046
Rnf2	ring finger protein 2	0.043
Cpeb2	cytoplasmic polyadenylation element binding protein 2	0.042	Mouse
Mcm3	minichromosome maintenance deficient 3 (S. cerevisiae)	0.042
Ncaph	non-SMC condensin I complex, subunit H	0.042
E2f8	E2F transcription factor 8	0.042
Zfand6	zinc finger, AN1-type domain 6	0.040
Ube2c	ubiquitin-conjugating enzyme E2C	0.040
Kif2c	kinesin family member 2C	0.039
Cenph	centromere protein H	0.039
Tob1	transducer of ErbB-2.1	0.038
Atrx	alpha thalassemia/mental retardation syndrome X-linked homolog (human)	0.038
Tbca	tubulin cofactor A	0.037
Cks2	CDC28 protein kinase regulatory subunit 2	0.037
Nek2	NIMA (never in mitosis gene a)-related expressed kinase 2	0.036
Tsc2	tuberous sclerosis 2	0.035
Dlgap5	discs, large (Drosophila) homolog-associated protein 5	0.033
Trp53	transformation related protein 53	0.033
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.032
Ccz1	CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)	0.032
Cenpe	centromere protein E	0.030
L3mbtl2	l(3)mbt-like 2 (Drosophila)	0.030
Paip2	polyadenylate-binding protein-interacting protein 2	0.030
Ccnf	cyclin F	0.029
Smc1b	structural maintenance of chromosomes 1B	0.028
Eif4a2	eukaryotic translation initiation factor 4A2	0.028
Pole2	polymerase (DNA directed), epsilon 2 (p59 subunit)	0.027
Fzr1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.027
Mad2l1	MAD2 mitotic arrest deficient-like 1 (yeast)	0.027
Mff	mitochondrial fission factor	0.026
Melk	maternal embryonic leucine zipper kinase	0.025
Kif11	kinesin family member 11	0.024
Eea1	early endosome antigen 1	0.023
Sycp2	synaptonemal complex protein 2	0.023
Stil	Scl/Tal1 interrupting locus	0.023
Rrm2	ribonucleotide reductase M2	0.023
Cdc6	cell division cycle 6 homolog (S. cerevisiae)	0.022
Kif4	kinesin family member 4	0.022
Nae1	NEDD8 activating enzyme E1 subunit 1	0.022
Espl1	extra spindle poles-like 1 (S. cerevisiae)	0.022
Cyct	cytochrome c, testis	0.022
Psmd10	proteasome (prosome, macropain) 26S subunit, non-ATPase, 10	0.021
Yipf4	Yip1 domain family, member 4	0.021
Stk31	serine threonine kinase 31	0.021
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.021
Hif1a	hypoxia inducible factor 1, alpha subunit	0.021
Vars	valyl-tRNA synthetase	0.021
Ppp1r7	protein phosphatase 1, regulatory (inhibitor) subunit 7	0.021
Rec8	REC8 homolog (yeast)	0.021
Nanog	Nanog homeobox	0.020
Tmem30a	transmembrane protein 30A	0.020
Pnpla8	patatin-like phospholipase domain containing 8	0.019
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.019
Depdc1b	DEP domain containing 1B	0.019
Tcfcp2l1	transcription factor CP2-like 1	0.019
Tdp1	tyrosyl-DNA phosphodiesterase 1	0.019
Tipin	timeless interacting protein	0.019
Cyth2	cytohesin 2	0.018
Vps72	vacuolar protein sorting 72 (yeast)	0.018
Fam83d	family with sequence similarity 83, member D	0.018
D1Pas1	DNA segment, Chr 1, Pasteur Institute 1	0.018
Hmmr	hyaluronan mediated motility receptor (RHAMM)	0.018
Samd8	sterile alpha motif domain containing 8	0.018
Naa38	N(alpha)-acetyltransferase 38, NatC auxiliary subunit	0.017
H1	histocompatibility 1	0.017
Cenpn	centromere protein N	0.017
Atg2a	ATG2 autophagy related 2 homolog A (S. cerevisiae)	0.017
Tk1	thymidine kinase 1	0.017
Plk1	polo-like kinase 1 (Drosophila)	0.017	Yeast
Git1	G protein-coupled receptor kinase-interactor 1	0.017
Haus4	HAUS augmin-like complex, subunit 4	0.017
Fam103a1	family with sequence similarity 103, member A1	0.017
Kif1b	kinesin family member 1B	0.017
Dctn1	dynactin 1	0.017
Skiv2l	superkiller viralicidic activity 2-like (S. cerevisiae)	0.017
Gga1	golgi associated, gamma adaptin ear containing, ARF binding protein 1	0.016
Prc1	protein regulator of cytokinesis 1	0.016
Men1	multiple endocrine neoplasia 1	0.016
Ska1	spindle and kinetochore associated complex subunit 1	0.016
Sugt1	SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)	0.016
Usp22	ubiquitin specific peptidase 22	0.016
Tubgcp2	tubulin, gamma complex associated protein 2	0.016
Cab39	calcium binding protein 39	0.016
Rbck1	RanBP-type and C3HC4-type zinc finger containing 1	0.016
Ctdnep1	CTD nuclear envelope phosphatase 1	0.016
Fbrs	fibrosin	0.016
Mcm7	minichromosome maintenance deficient 7 (S. cerevisiae)	0.016
Syce1	synaptonemal complex central element protein 1	0.016
Mki67	antigen identified by monoclonal antibody Ki 67	0.016
Ndfip2	Nedd4 family interacting protein 2	0.016
Nr1h2	nuclear receptor subfamily 1, group H, member 2	0.016
Fam126b	family with sequence similarity 126, member B	0.016
Cpeb3	cytoplasmic polyadenylation element binding protein 3	0.015	Mouse
Ckap2l	cytoskeleton associated protein 2-like	0.015
Ppm1a	protein phosphatase 1A, magnesium dependent, alpha isoform	0.015
Fam134b	family with sequence similarity 134, member B	0.015
2810417H13Rik	RIKEN cDNA 2810417H13 gene	0.015
Tex11	testis expressed gene 11	0.015
Mcam	melanoma cell adhesion molecule	0.015
Cdk4	cyclin-dependent kinase 4	0.015
Ldb1	LIM domain binding 1	0.015
1110028C15Rik	RIKEN cDNA 1110028C15 gene	0.014
Med16	mediator complex subunit 16	0.014
Ccdc123	coiled-coil domain containing 123	0.014
Supt5h	suppressor of Ty 5 homolog (S. cerevisiae)	0.014
Yeats2	YEATS domain containing 2	0.014
Mdm2	transformed mouse 3T3 cell double minute 2	0.014
Hormad1	HORMA domain containing 1	0.014
A930001N09Rik	RIKEN cDNA A930001N09 gene	0.014
Hspa14	heat shock protein 14	0.014
Nasp	nuclear autoantigenic sperm protein (histone-binding)	0.014
Brd7	bromodomain containing 7	0.014
Topbp1	topoisomerase (DNA) II binding protein 1	0.014
Tuba1b	tubulin, alpha 1B	0.014
March6	membrane-associated ring finger (C3HC4) 6	0.013
Ppp4c	protein phosphatase 4, catalytic subunit	0.013
Mdm4	transformed mouse 3T3 cell double minute 4	0.013
Rpa2	replication protein A2	0.013
Adcy9	adenylate cyclase 9	0.013
Hist1h1a	histone cluster 1, H1a	0.013
Nr0b1	nuclear receptor subfamily 0, group B, member 1	0.013
Ppp1cb	protein phosphatase 1, catalytic subunit, beta isoform	0.013
Ulk2	Unc-51 like kinase 2 (C. elegans)	0.013
Pmf1	polyamine-modulated factor 1	0.013
Med21	mediator complex subunit 21	0.013
Napb	N-ethylmaleimide sensitive fusion protein attachment protein beta	0.013
Ptov1	prostate tumor over expressed gene 1	0.013
Trim54	tripartite motif-containing 54	0.012
Cyb5r4	cytochrome b5 reductase 4	0.012
Ephb4	Eph receptor B4	0.012
Mad2l1bp	MAD2L1 binding protein	0.012
Shcbp1	Shc SH2-domain binding protein 1	0.012
Rad21	RAD21 homolog (S. pombe)	0.012
Mtbp	Mdm2, transformed 3T3 cell double minute p53 binding protein	0.012
Rnf34	ring finger protein 34	0.012
3110043O21Rik	RIKEN cDNA 3110043O21 gene	0.012
Hmgb2	high mobility group box 2	0.012
Zfp42	zinc finger protein 42	0.012
Pik3c3	phosphoinositide-3-kinase, class 3	0.012
Bhlhe40	basic helix-loop-helix family, member e40	0.012
Mcf2	mcf.2 transforming sequence	0.012
Sec23a	SEC23A (S. cerevisiae)	0.012
Gtf2b	general transcription factor IIB	0.012
Ankrd13c	ankyrin repeat domain 13c	0.012
Dcaf15	DDB1 and CUL4 associated factor 15	0.012
Tcfl5	transcription factor-like 5 (basic helix-loop-helix)	0.012
Pdcl2	phosducin-like 2	0.012
Rnf19b	ring finger protein 19B	0.012
Kif21a	kinesin family member 21A	0.012
Mtch1	mitochondrial carrier homolog 1 (C. elegans)	0.011
Cdkn3	cyclin-dependent kinase inhibitor 3	0.011
Rad51	RAD51 homolog (S. cerevisiae)	0.011
Zfy2	zinc finger protein 2, Y linked	0.011
Nde1	nuclear distribution gene E homolog 1 (A nidulans)	0.011
Ube2t	ubiquitin-conjugating enzyme E2T (putative)	0.011
Pcmt1	protein-L-isoaspartate (D-aspartate) O-methyltransferase 1	0.011
Hmgb1	high mobility group box 1	0.011
Rrm1	ribonucleotide reductase M1	0.011
Cc2d1a	coiled-coil and C2 domain containing 1A	0.011
Rasl2-9-ps	RAS-like, family 2, locus 9, pseudogene	0.011
Ube3b	ubiquitin protein ligase E3B	0.011
Ubl3	ubiquitin-like 3	0.011
Tesk1	testis specific protein kinase 1	0.011
Cdca7	cell division cycle associated 7	0.011
Mastl	microtubule associated serine/threonine kinase-like	0.011
Nptn	neuroplastin	0.011
Bub1	budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)	0.011
Gadd45a	growth arrest and DNA-damage-inducible 45 alpha	0.011
Pbk	PDZ binding kinase	0.011
Hdac1	histone deacetylase 1	0.011
Skil	SKI-like	0.011
1810013L24Rik	RIKEN cDNA 1810013L24 gene	0.011
Dazl	deleted in azoospermia-like	0.011
Rrm2b	ribonucleotide reductase M2 B (TP53 inducible)	0.011
Gtse1	G two S phase expressed protein 1	0.011
Sbf1	SET binding factor 1	0.011
Rab9	RAB9, member RAS oncogene family	0.011
2310004I24Rik	RIKEN cDNA 2310004I24 gene	0.011
Pacrg	PARK2 co-regulated	0.010
Ccdc99	coiled-coil domain containing 99	0.010
Trim59	tripartite motif-containing 59	0.010
Hnrnpl	heterogeneous nuclear ribonucleoprotein L	0.010
Atp6v1a	ATPase, H+ transporting, lysosomal V1 subunit A	0.010
Lpgat1	lysophosphatidylglycerol acyltransferase 1	0.010
Ddx4	DEAD (Asp-Glu-Ala-Asp) box polypeptide 4	0.010
Gmnn	geminin	0.010
Rybp	RING1 and YY1 binding protein	0.010
Acyp1	acylphosphatase 1, erythrocyte (common) type	0.010
Rnf17	ring finger protein 17	0.010
Meig1	meiosis expressed gene 1	0.010
Smap1	stromal membrane-associated protein 1	0.010
Ttc33	tetratricopeptide repeat domain 33	0.010
Mllt1	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1	0.010