Mus musculus

117 known processes

Esr2

estrogen receptor 2 (beta)

(Aliases: ERbeta,ER[b],Estrb)

Esr2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organ growth GO:0035265 117 0.946
Mouse
intracellular receptor signaling pathway GO:0030522 74 0.891
tertiary branching involved in mammary gland duct morphogenesis GO:0060748 3 0.877
antral ovarian follicle growth GO:0001547 5 0.875
Mouse
negative regulation of cell proliferation GO:0008285 296 0.868
cellular amino acid metabolic process GO:0006520 103 0.866
regulation of hormone levels GO:0010817 211 0.859
Mouse
development of primary female sexual characteristics GO:0046545 73 0.849
generation of precursor metabolites and energy GO:0006091 103 0.834
regulation of cellular amino acid metabolic process GO:0006521 5 0.764
synaptic transmission GO:0007268 329 0.755
hormone secretion GO:0046879 128 0.734
ovulation cycle GO:0042698 59 0.727
multicellular organism growth GO:0035264 161 0.718
regulation of nucleotide biosynthetic process GO:0030808 34 0.717
cellular ketone metabolic process GO:0042180 84 0.705
spermatogenesis GO:0007283 284 0.703
metal ion homeostasis GO:0055065 189 0.689
regulation of secretion GO:0051046 274 0.682
establishment of protein localization to organelle GO:0072594 118 0.682
calcium ion transport GO:0006816 159 0.661
ovarian follicle development GO:0001541 40 0.660
peptide transport GO:0015833 133 0.659
digestive system development GO:0055123 200 0.659
regulation of cellular ketone metabolic process GO:0010565 66 0.651
regulation of organelle organization GO:0033043 289 0.615
regulation of wnt signaling pathway GO:0030111 123 0.611
prostate gland development GO:0030850 48 0.592
regulation of intracellular transport GO:0032386 159 0.590
neuropeptide signaling pathway GO:0007218 19 0.573
calcium ion homeostasis GO:0055074 127 0.573
amide transport GO:0042886 138 0.566
stem cell development GO:0048864 219 0.562
Mouse
negative regulation of hormone secretion GO:0046888 20 0.561
muscle cell proliferation GO:0033002 52 0.557
Rat
ossification GO:0001503 216 0.557
regulation of cell migration GO:0030334 219 0.555
cellular amine metabolic process GO:0044106 44 0.552
cell fate commitment GO:0045165 210 0.551
carbohydrate metabolic process GO:0005975 230 0.542
response to peptide hormone GO:0043434 127 0.534
lactation GO:0007595 25 0.533
divalent metal ion transport GO:0070838 172 0.533
rhythmic process GO:0048511 174 0.533
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.529
negative regulation of epithelial cell proliferation GO:0050680 64 0.526
hormone metabolic process GO:0042445 86 0.524
Mouse
hormone mediated signaling pathway GO:0009755 23 0.524
prostate gland growth GO:0060736 13 0.515
Mouse
mapk cascade GO:0000165 281 0.513
Rat
female gonad development GO:0008585 71 0.510
locomotory behavior GO:0007626 195 0.505
steroid metabolic process GO:0008202 119 0.505
Mouse
digestive tract development GO:0048565 190 0.495
cellular metal ion homeostasis GO:0006875 151 0.492
regulation of steroid biosynthetic process GO:0050810 26 0.492
muscle system process GO:0003012 141 0.492
intracellular protein transport GO:0006886 204 0.485
hindbrain development GO:0030902 128 0.482
Rat
g protein coupled receptor signaling pathway GO:0007186 243 0.467
nuclear transport GO:0051169 139 0.465
regulation of feeding behavior GO:0060259 3 0.464
Rat
female gamete generation GO:0007292 74 0.452
negative regulation of androgen receptor signaling pathway GO:0060766 3 0.452
positive regulation of cell death GO:0010942 224 0.444
Rat
response to nutrient levels GO:0031667 109 0.442
Rat
female sex differentiation GO:0046660 84 0.438
prostate gland epithelium morphogenesis GO:0060740 31 0.432
regulation of mapk cascade GO:0043408 248 0.430
Rat
regulation of protein localization GO:0032880 231 0.429
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.425
regulation of carbohydrate biosynthetic process GO:0043255 40 0.423
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 18 0.422
positive regulation of neuron differentiation GO:0045666 141 0.407
positive regulation of transferase activity GO:0051347 167 0.401
positive regulation of camp mediated signaling GO:0043950 3 0.396
negative regulation of insulin secretion GO:0046676 14 0.395
circulatory system process GO:0003013 197 0.391
progesterone metabolic process GO:0042448 4 0.386
cytokine production GO:0001816 319 0.385
regionalization GO:0003002 337 0.381
wnt signaling pathway GO:0016055 188 0.375
negative regulation of peptide hormone secretion GO:0090278 16 0.367
canonical wnt signaling pathway GO:0060070 130 0.365
adult locomotory behavior GO:0008344 91 0.364
germ cell development GO:0007281 185 0.364
positive regulation of apoptotic process GO:0043065 217 0.360
Rat
regulation of peptide secretion GO:0002791 77 0.355
dna recombination GO:0006310 92 0.353
prostate gland morphogenesis GO:0060512 32 0.353
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.351
follicle stimulating hormone secretion GO:0046884 1 0.343
positive regulation of nucleotide biosynthetic process GO:0030810 26 0.342
mammary gland branching involved in pregnancy GO:0060745 6 0.338
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.338
positive regulation of growth GO:0045927 104 0.337
drug catabolic process GO:0042737 2 0.337
protein localization to nucleus GO:0034504 121 0.336
protein localization to organelle GO:0033365 185 0.335
regulation of lateral mesodermal cell fate specification GO:0048378 2 0.332
cellular response to cytokine stimulus GO:0071345 189 0.327
urogenital system development GO:0001655 261 0.327
regulation of kinase activity GO:0043549 249 0.325
carbohydrate homeostasis GO:0033500 128 0.322
circadian rhythm GO:0007623 114 0.322
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.321
regulation of metal ion transport GO:0010959 106 0.320
response to organonitrogen compound GO:0010243 246 0.320
regulation of transmembrane transport GO:0034762 128 0.318
male gamete generation GO:0048232 285 0.317
developmental maturation GO:0021700 193 0.316
tyrosine phosphorylation of stat5 protein GO:0042506 9 0.315
regulation of mesenchymal cell proliferation GO:0010464 37 0.314
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.313
regulation of system process GO:0044057 200 0.311
regulation of hormone secretion GO:0046883 88 0.308
b cell activation GO:0042113 161 0.306
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.303
leukocyte differentiation GO:0002521 342 0.301
regulation of cellular response to stress GO:0080135 159 0.298
anatomical structure homeostasis GO:0060249 145 0.298
positive regulation of smad protein import into nucleus GO:0060391 2 0.296
negative regulation of growth GO:0045926 99 0.294
divalent inorganic cation transport GO:0072511 178 0.291
regulation of cell motility GO:2000145 236 0.291
amine metabolic process GO:0009308 45 0.289
cation transport GO:0006812 399 0.287
cation homeostasis GO:0055080 212 0.286
positive regulation of neuron apoptotic process GO:0043525 25 0.286
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.286
protein targeting GO:0006605 143 0.278
positive regulation of intracellular transport GO:0032388 70 0.277
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.275
erythrocyte differentiation GO:0030218 88 0.273
negative regulation of secretion by cell GO:1903531 54 0.272
regulation of epithelial cell proliferation GO:0050678 141 0.272
trophectodermal cellular morphogenesis GO:0001831 3 0.270
Mouse
regulation of peptidase activity GO:0052547 96 0.269
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.269
morphogenesis of a branching structure GO:0001763 203 0.269
Mouse
regulation of cell cycle GO:0051726 281 0.267
positive regulation of inositol phosphate biosynthetic process GO:0060732 2 0.266
mammary gland lobule development GO:0061377 22 0.266
Mouse
regulation of carbohydrate metabolic process GO:0006109 75 0.264
positive regulation of intracellular steroid hormone receptor signaling pathway GO:0033145 4 0.264
positive regulation of activin receptor signaling pathway GO:0032927 3 0.264
mesonephric tubule development GO:0072164 94 0.263
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.262
regulation of transferase activity GO:0051338 263 0.260
lipid transport GO:0006869 98 0.260
endocrine system development GO:0035270 98 0.258
regulation of cellular amine metabolic process GO:0033238 20 0.257
negative regulation of secretion GO:0051048 61 0.257
apoptotic signaling pathway GO:0097190 306 0.257
maternal placenta development GO:0001893 20 0.253
cellular carbohydrate metabolic process GO:0044262 119 0.253
somatostatin signaling pathway GO:0038170 2 0.252
cardiac muscle tissue development GO:0048738 130 0.251
regulation of the force of heart contraction GO:0002026 17 0.251
segmentation GO:0035282 93 0.250
lateral mesoderm morphogenesis GO:0048369 3 0.248
regulation of blood vessel size GO:0050880 56 0.247
regulation of protein localization to nucleus GO:1900180 60 0.246
lipid localization GO:0010876 126 0.245
lung development GO:0030324 164 0.242
regulation of generation of precursor metabolites and energy GO:0043467 38 0.241
regulation of tube size GO:0035150 57 0.239
positive regulation of mapk cascade GO:0043410 170 0.238
Rat
positive regulation of cell activation GO:0050867 158 0.236
regulation of nucleocytoplasmic transport GO:0046822 73 0.235
somatostatin receptor signaling pathway GO:0038169 2 0.233
positive regulation of peptidase activity GO:0010952 49 0.232
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.229
peptide hormone secretion GO:0030072 109 0.228
purine containing compound biosynthetic process GO:0072522 70 0.224
cellular response to acid chemical GO:0071229 68 0.222
asymmetric neuroblast division GO:0055059 1 0.221
response to estradiol GO:0032355 12 0.220
Rat
glial cell differentiation GO:0010001 131 0.219
bone development GO:0060348 120 0.219
regulation of glycogen metabolic process GO:0070873 13 0.217
positive regulation of cell cycle GO:0045787 92 0.217
mammary gland morphogenesis GO:0060443 54 0.216
Mouse
regulation of secretion by cell GO:1903530 249 0.215
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.215
blood vessel remodeling GO:0001974 33 0.213
heart growth GO:0060419 45 0.213
embryonic organ morphogenesis GO:0048562 276 0.213
stem cell differentiation GO:0048863 268 0.212
Mouse
positive regulation of apoptotic signaling pathway GO:2001235 95 0.211
natural killer cell proliferation GO:0001787 3 0.210
regulation of fatty acid metabolic process GO:0019217 28 0.210
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.209
stem cell maintenance GO:0019827 130 0.208
Mouse
dna templated transcriptional preinitiation complex assembly GO:0070897 4 0.208
kidney development GO:0001822 213 0.208
digestive tract morphogenesis GO:0048546 147 0.205
regulation of fatty acid oxidation GO:0046320 10 0.205
peptide secretion GO:0002790 114 0.205
temperature homeostasis GO:0001659 26 0.202
insulin secretion GO:0030073 89 0.202
regulation of peptide transport GO:0090087 91 0.201
epithelial tube morphogenesis GO:0060562 303 0.199
Mouse
cytokine mediated signaling pathway GO:0019221 115 0.197
ammonia assimilation cycle GO:0019676 2 0.196
regulation of protein kinase activity GO:0045859 232 0.196
dna metabolic process GO:0006259 303 0.195
monocarboxylic acid metabolic process GO:0032787 191 0.194
regulation of muscle system process GO:0090257 80 0.193
regulation of cell division GO:0051302 76 0.193
glucose homeostasis GO:0042593 128 0.188
positive regulation of programmed cell death GO:0043068 218 0.187
Rat
nitrogen compound transport GO:0071705 271 0.187
alpha amino acid metabolic process GO:1901605 59 0.187
mast cell proliferation GO:0070662 4 0.186
regulation of hydrolase activity GO:0051336 246 0.185
luteinization GO:0001553 8 0.185
central nervous system neuron differentiation GO:0021953 162 0.184
response to lipopolysaccharide GO:0032496 128 0.182
regulation of ion transport GO:0043269 215 0.182
cytoplasmic transport GO:0016482 234 0.180
cell proliferation in hindbrain GO:0021534 10 0.180
epithelial cell differentiation involved in prostate gland development GO:0060742 13 0.179
lateral mesoderm formation GO:0048370 3 0.179
cyclic purine nucleotide metabolic process GO:0052652 43 0.178
regulation of protein targeting GO:1903533 61 0.178
positive regulation of cellular amine metabolic process GO:0033240 5 0.177
multi multicellular organism process GO:0044706 109 0.176
Mouse
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.176
respiratory tube development GO:0030323 167 0.175
regulation of neurotransmitter uptake GO:0051580 6 0.174
angiogenesis GO:0001525 201 0.173
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.171
cellular ion homeostasis GO:0006873 165 0.171
renal system development GO:0072001 225 0.171
actin filament bundle assembly GO:0051017 40 0.170
regulation of glucose metabolic process GO:0010906 60 0.170
cellular homeostasis GO:0019725 240 0.169
regulation of blood pressure GO:0008217 93 0.166
divalent inorganic cation homeostasis GO:0072507 138 0.165
eating behavior GO:0042755 15 0.165
cellular response to peptide hormone stimulus GO:0071375 92 0.165
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 4 0.164
cellular divalent inorganic cation homeostasis GO:0072503 127 0.164
response to organic cyclic compound GO:0014070 198 0.163
Zebrafish Mouse Rat
regulation of cell activation GO:0050865 289 0.162
establishment of planar polarity GO:0001736 28 0.161
alpha beta t cell differentiation GO:0046632 69 0.161
syncytium formation by plasma membrane fusion GO:0000768 42 0.161
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.160
chromatin modification GO:0016568 187 0.160
positive regulation of wnt signaling pathway GO:0030177 45 0.160
bmp signaling pathway GO:0030509 93 0.160
branching morphogenesis of an epithelial tube GO:0048754 159 0.160
Mouse
positive regulation of protein modification process GO:0031401 299 0.159
regulation of stem cell proliferation GO:0072091 78 0.158
branching involved in salivary gland morphogenesis GO:0060445 26 0.156
intracellular steroid hormone receptor signaling pathway GO:0030518 29 0.155
positive regulation of endopeptidase activity GO:0010950 43 0.155
regulation of mast cell differentiation GO:0060375 3 0.155
cellular response to hormone stimulus GO:0032870 150 0.154
muscle contraction GO:0006936 101 0.153
regulation of camp metabolic process GO:0030814 30 0.153
regulation of peptidyl serine phosphorylation GO:0033135 39 0.153
positive regulation of smooth muscle cell migration GO:0014911 4 0.151
long term synaptic potentiation GO:0060291 25 0.151
regulation of calcium ion transport into cytosol GO:0010522 31 0.148
regulation of ion transmembrane transport GO:0034765 119 0.148
asymmetric stem cell division GO:0098722 3 0.148
exocrine system development GO:0035272 45 0.147
myeloid leukocyte differentiation GO:0002573 119 0.147
t cell activation GO:0042110 289 0.146
positive regulation of lymphocyte proliferation GO:0050671 70 0.146
trophectodermal cell proliferation GO:0001834 2 0.146
Mouse
positive regulation of kinase activity GO:0033674 155 0.145
regulation of cytoplasmic transport GO:1903649 112 0.143
regulation of vitamin d biosynthetic process GO:0060556 1 0.142
nucleocytoplasmic transport GO:0006913 139 0.141
positive regulation of behavior GO:0048520 40 0.141
epidermis development GO:0008544 187 0.141
lateral mesodermal cell differentiation GO:0048371 3 0.140
lymphocyte differentiation GO:0030098 242 0.139
cellular response to peptide GO:1901653 92 0.139
regulation of canonical wnt signaling pathway GO:0060828 82 0.138
cellular response to organic cyclic compound GO:0071407 87 0.137
Zebrafish Mouse Rat
cell growth GO:0016049 130 0.137
positive regulation of cellular component biogenesis GO:0044089 94 0.137
regulation of blood circulation GO:1903522 93 0.137
regulation of neuron projection development GO:0010975 169 0.136
regulation of multi organism process GO:0043900 111 0.136
adult behavior GO:0030534 135 0.135
placenta development GO:0001890 140 0.135
Mouse
regulation of steroid hormone biosynthetic process GO:0090030 4 0.135
regulation of calcium ion transport GO:0051924 69 0.135
positive regulation of camp metabolic process GO:0030816 19 0.135
regulation of voltage gated calcium channel activity GO:1901385 4 0.135
blastocyst development GO:0001824 80 0.134
Mouse
decidualization GO:0046697 10 0.134
peptidyl tyrosine modification GO:0018212 145 0.134
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.134
pancreas development GO:0031016 57 0.134
myeloid cell differentiation GO:0030099 233 0.134
cellular calcium ion homeostasis GO:0006874 119 0.134
regulation of saliva secretion GO:0046877 2 0.133
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.130
osteoblast development GO:0002076 17 0.129
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.129
cellular response to gonadotropin stimulus GO:0071371 4 0.128
spermatid differentiation GO:0048515 115 0.128
response to molecule of bacterial origin GO:0002237 143 0.128
positive regulation of cytoplasmic transport GO:1903651 40 0.127
chromatin organization GO:0006325 206 0.127
positive regulation of canonical wnt signaling pathway GO:0090263 29 0.125
heart morphogenesis GO:0003007 178 0.125
positive regulation of glycolytic process GO:0045821 4 0.124
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.124
regulation of protein serine threonine kinase activity GO:0071900 157 0.124
positive regulation of stem cell proliferation GO:2000648 59 0.124
epithelial cell proliferation GO:0050673 174 0.122
regulation of mitotic cell cycle GO:0007346 126 0.122
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.120
regulation of t cell activation GO:0050863 170 0.120
regulation of adaptive immune response GO:0002819 90 0.120
lung morphogenesis GO:0060425 50 0.120
regulation of cell cycle process GO:0010564 160 0.119
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.118
creatinine metabolic process GO:0046449 3 0.118
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest GO:0006977 3 0.118
ribonucleotide metabolic process GO:0009259 291 0.116
mitotic cell cycle GO:0000278 195 0.116
cyclic nucleotide mediated signaling GO:0019935 18 0.116
regulation of myeloid leukocyte differentiation GO:0002761 58 0.116
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.115
positive regulation of activated t cell proliferation GO:0042104 8 0.115
developmental growth involved in morphogenesis GO:0060560 138 0.115
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.115
Mouse
odontogenesis of dentin containing tooth GO:0042475 66 0.114
multicellular organismal homeostasis GO:0048871 164 0.114
cellular response to follicle stimulating hormone stimulus GO:0071372 1 0.114
fatty acid metabolic process GO:0006631 121 0.113
neuron death GO:0070997 154 0.113
Rat
pituitary gland development GO:0021983 38 0.112
body fluid secretion GO:0007589 53 0.112
establishment of neuroblast polarity GO:0045200 1 0.111
mesenchyme development GO:0060485 152 0.111
connective tissue development GO:0061448 179 0.110
response to extracellular stimulus GO:0009991 127 0.110
Rat
negative regulation of phosphorus metabolic process GO:0010563 184 0.110
hair follicle development GO:0001942 85 0.109
regulation of carbohydrate catabolic process GO:0043470 12 0.109
ribose phosphate biosynthetic process GO:0046390 59 0.109
mammary gland duct morphogenesis GO:0060603 38 0.109
Mouse
phospholipid metabolic process GO:0006644 87 0.107
response to steroid hormone GO:0048545 56 0.107
Zebrafish Mouse Rat
protein kinase b signaling GO:0043491 74 0.107
water homeostasis GO:0030104 27 0.107
embryonic skeletal system development GO:0048706 120 0.106
regulation of circadian rhythm GO:0042752 58 0.104
regulation of intracellular protein transport GO:0033157 82 0.104
mesenchymal cell proliferation GO:0010463 44 0.103
g protein coupled receptor signaling pathway involved in heart process GO:0086103 4 0.102
regulation of protein transport GO:0051223 163 0.101
regulation of lymphocyte proliferation GO:0050670 117 0.101
striated muscle tissue development GO:0014706 293 0.101
positive regulation of peptidyl serine phosphorylation GO:0033138 25 0.101
response to corticosteroid GO:0031960 20 0.100
Rat
response to growth factor GO:0070848 198 0.100
sterol homeostasis GO:0055092 45 0.100
negative regulation of epithelial cell proliferation involved in prostate gland development GO:0060770 7 0.100
regulation of steroid metabolic process GO:0019218 39 0.100
regulation of protein import into nucleus GO:0042306 52 0.099
positive regulation of protein import into nucleus GO:0042307 26 0.099
oxidation reduction process GO:0055114 342 0.099
regulation of renal sodium excretion GO:0035813 3 0.099
respiratory system development GO:0060541 190 0.099
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.098
positive regulation of protein phosphorylation GO:0001934 242 0.098
positive regulation of b cell proliferation GO:0030890 24 0.098
development of primary sexual characteristics GO:0045137 143 0.098
memory GO:0007613 58 0.098
blood circulation GO:0008015 195 0.098
positive regulation of leukocyte proliferation GO:0070665 73 0.097
regulation of peptide hormone secretion GO:0090276 75 0.097
camera type eye development GO:0043010 266 0.097
dicarboxylic acid metabolic process GO:0043648 18 0.097
regulation of cell adhesion GO:0030155 154 0.097
cellular response to transforming growth factor beta stimulus GO:0071560 88 0.097
second messenger mediated signaling GO:0019932 73 0.097
activation of adenylate cyclase activity GO:0007190 4 0.097
blood vessel morphogenesis GO:0048514 285 0.097
camp biosynthetic process GO:0006171 31 0.096
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.096
axonogenesis GO:0007409 274 0.096
neurotransmitter transport GO:0006836 76 0.096
cellular carbohydrate catabolic process GO:0044275 15 0.095
positive regulation of t cell activation GO:0050870 101 0.095
smad protein complex assembly GO:0007183 1 0.095
positive regulation of insulin receptor signaling pathway GO:0046628 4 0.095
ras protein signal transduction GO:0007265 77 0.095
positive regulation of intracellular protein transport GO:0090316 42 0.095
regulation of camp biosynthetic process GO:0030817 25 0.095
response to insulin GO:0032868 100 0.094
mesenchymal cell development GO:0014031 93 0.094
acute inflammatory response GO:0002526 41 0.094
cytosolic calcium ion homeostasis GO:0051480 70 0.093
peptidyl tyrosine phosphorylation GO:0018108 143 0.093
hexose metabolic process GO:0019318 98 0.093
ovulation from ovarian follicle GO:0001542 9 0.092
muscle cell differentiation GO:0042692 261 0.092
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.092
chemotaxis GO:0006935 247 0.092
prostate epithelial cord elongation GO:0060523 3 0.092
Mouse
regulation of protein depolymerization GO:1901879 26 0.092
kidney rudiment formation GO:0072003 3 0.091
regulation of cell size GO:0008361 72 0.091
extrinsic apoptotic signaling pathway GO:0097191 126 0.091
regulation of leukocyte differentiation GO:1902105 159 0.090
negative regulation of phosphorylation GO:0042326 166 0.090
regulation of t cell differentiation GO:0045580 83 0.090
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 20 0.090
negative regulation of multi organism process GO:0043901 68 0.089
striated muscle cell development GO:0055002 125 0.089
positive regulation of mitotic cell cycle GO:0045931 41 0.089
establishment or maintenance of neuroblast polarity GO:0045196 1 0.088
lung induction GO:0060492 3 0.088
regulation of the force of heart contraction by chemical signal GO:0003057 5 0.088
response to starvation GO:0042594 65 0.088
cellular chemical homeostasis GO:0055082 215 0.087
embryonic placenta development GO:0001892 98 0.087
Mouse
response to radiation GO:0009314 165 0.087
embryonic limb morphogenesis GO:0030326 126 0.087
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.087
glucose metabolic process GO:0006006 92 0.087
spinal cord development GO:0021510 81 0.087
maternal process involved in female pregnancy GO:0060135 32 0.087
Mouse
sulfur compound metabolic process GO:0006790 100 0.086
response to peptide GO:1901652 136 0.086
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.086
regulation of mitosis GO:0007088 29 0.085
ureteric bud development GO:0001657 94 0.085
peptidyl amino acid modification GO:0018193 336 0.084
regulation of cysteine type endopeptidase activity GO:2000116 65 0.084
regulation of nitrogen cycle metabolic process GO:1903314 1 0.084
inflammatory response GO:0006954 244 0.083
regulation of growth hormone secretion GO:0060123 5 0.082
embryonic heart tube morphogenesis GO:0003143 51 0.082
glucose import GO:0046323 32 0.082
regulation of glucocorticoid secretion GO:2000849 5 0.081
positive regulation of cell division GO:0051781 31 0.081
negative regulation of peptide secretion GO:0002792 16 0.079
regulation of nuclear division GO:0051783 56 0.079
skeletal muscle cell differentiation GO:0035914 66 0.079
gland development GO:0048732 330 0.078
negative regulation of cell cycle GO:0045786 123 0.078
calcium mediated signaling GO:0019722 46 0.078
negative regulation of molecular function GO:0044092 258 0.078
monosaccharide metabolic process GO:0005996 106 0.077
dephosphorylation GO:0016311 129 0.077
purine nucleotide biosynthetic process GO:0006164 65 0.076
lung lobe morphogenesis GO:0060463 9 0.076
glutamine family amino acid metabolic process GO:0009064 15 0.076
regulation of protein complex assembly GO:0043254 83 0.076
endodermal cell fate specification GO:0001714 4 0.075
regulation of stress fiber assembly GO:0051492 15 0.075
cartilage development GO:0051216 140 0.075
organic hydroxy compound metabolic process GO:1901615 203 0.075
regulation of epidermal cell differentiation GO:0045604 21 0.075
regulation of endopeptidase activity GO:0052548 89 0.075
lipid homeostasis GO:0055088 63 0.074
regulation of insulin receptor signaling pathway GO:0046626 21 0.074
positive regulation of fatty acid oxidation GO:0046321 4 0.074
maintenance of cell number GO:0098727 3 0.074
mesodermal cell migration GO:0008078 4 0.074
negative regulation of cell motility GO:2000146 61 0.074
sensory organ morphogenesis GO:0090596 242 0.074
purine nucleotide metabolic process GO:0006163 302 0.073
action potential GO:0001508 78 0.073
activation of cysteine type endopeptidase activity GO:0097202 27 0.073
positive regulation of protein kinase activity GO:0045860 144 0.073
purine ribonucleotide biosynthetic process GO:0009152 59 0.072
lateral sprouting involved in mammary gland duct morphogenesis GO:0060599 2 0.072
posttranscriptional regulation of gene expression GO:0010608 155 0.072
heat generation GO:0031649 13 0.072
regulation of lymphocyte differentiation GO:0045619 107 0.071
response to cholesterol GO:0070723 4 0.071
single organism nuclear import GO:1902593 95 0.071
regulation of gluconeogenesis GO:0006111 30 0.070
t cell differentiation GO:0030217 174 0.070
central nervous system vasculogenesis GO:0022009 3 0.070
cellular response to inorganic substance GO:0071241 37 0.070
negative regulation of phosphate metabolic process GO:0045936 184 0.070

Esr2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.137
disease of anatomical entity DOID:7 0 0.118
endocrine system disease DOID:28 0 0.118
female reproductive system disease DOID:229 0 0.117
reproductive system disease DOID:15 0 0.117