Mus musculus

54 known processes

Hspg2

perlecan (heparan sulfate proteoglycan 2)

(Aliases: Plc,Pcn,per,AI852380)

Hspg2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chondrocyte differentiation GO:0002062 72 0.981
epithelial tube morphogenesis GO:0060562 303 0.980
stem cell development GO:0048864 219 0.977
regionalization GO:0003002 337 0.961
cell migration involved in endocardial cushion formation GO:0003273 3 0.959
axonogenesis GO:0007409 274 0.958
bone development GO:0060348 120 0.956
neuron projection guidance GO:0097485 141 0.949
connective tissue development GO:0061448 179 0.940
branching morphogenesis of an epithelial tube GO:0048754 159 0.938
metanephros morphogenesis GO:0003338 24 0.928
regulation of cell adhesion GO:0030155 154 0.927
Mouse
gliogenesis GO:0042063 141 0.925
cardiac muscle tissue development GO:0048738 130 0.911
axon guidance GO:0007411 141 0.909
cartilage condensation GO:0001502 18 0.903
salivary gland development GO:0007431 37 0.898
regulation of osteoblast proliferation GO:0033688 15 0.894
morphogenesis of a branching structure GO:0001763 203 0.893
lung development GO:0030324 164 0.890
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.882
forebrain development GO:0030900 302 0.881
glial cell differentiation GO:0010001 131 0.881
digestive tract development GO:0048565 190 0.874
extracellular matrix organization GO:0030198 147 0.872
embryonic skeletal system development GO:0048706 120 0.871
skeletal system morphogenesis GO:0048705 203 0.870
gland development GO:0048732 330 0.870
morphogenesis of a branching epithelium GO:0061138 193 0.866
skeletal system development GO:0001501 356 0.862
cellular response to growth factor stimulus GO:0071363 197 0.861
regulation of cardiac cell fate specification GO:2000043 1 0.861
formation of radial glial scaffolds GO:0021943 4 0.861
cardiac endothelial cell differentiation GO:0003348 4 0.859
heart morphogenesis GO:0003007 178 0.854
skeletal muscle organ development GO:0060538 163 0.848
mesenchymal cell differentiation GO:0048762 107 0.847
appendage morphogenesis GO:0035107 149 0.845
limb morphogenesis GO:0035108 149 0.845
cardiac septum morphogenesis GO:0060411 46 0.842
striated muscle tissue development GO:0014706 293 0.838
cell adhesion GO:0007155 329 0.837
Mouse
smooth muscle tissue development GO:0048745 22 0.834
ras protein signal transduction GO:0007265 77 0.832
retinal blood vessel morphogenesis GO:0061304 3 0.828
regulation of chondrocyte differentiation GO:0032330 33 0.827
respiratory system development GO:0060541 190 0.826
astrocyte fate commitment GO:0060018 4 0.825
neuron migration GO:0001764 122 0.822
cardiocyte differentiation GO:0035051 87 0.819
cell substrate adhesion GO:0031589 130 0.819
Mouse
appendage development GO:0048736 166 0.810
myotube differentiation GO:0014902 105 0.793
neural tube closure GO:0001843 90 0.793
regulation of cell migration GO:0030334 219 0.788
extracellular structure organization GO:0043062 148 0.788
cardiac right atrium morphogenesis GO:0003213 3 0.784
oviduct development GO:0060066 3 0.784
muscle cell differentiation GO:0042692 261 0.783
Worm
synapse organization GO:0050808 125 0.782
Mouse
positive regulation of cartilage development GO:0061036 18 0.779
nephron epithelium morphogenesis GO:0072088 68 0.779
response to growth factor GO:0070848 198 0.776
regulation of cell motility GO:2000145 236 0.772
limb development GO:0060173 166 0.770
nerve development GO:0021675 67 0.769
face development GO:0060324 38 0.764
cell matrix adhesion GO:0007160 68 0.761
sensory organ morphogenesis GO:0090596 242 0.751
regulation of cartilage development GO:0061035 44 0.745
morphogenesis of embryonic epithelium GO:0016331 159 0.740
cartilage development GO:0051216 140 0.738
kidney development GO:0001822 213 0.736
stem cell differentiation GO:0048863 268 0.732
retina development in camera type eye GO:0060041 119 0.726
mesenchymal cell development GO:0014031 93 0.726
cell proliferation involved in outflow tract morphogenesis GO:0061325 4 0.725
ossification GO:0001503 216 0.725
developmental maturation GO:0021700 193 0.722
artery development GO:0060840 53 0.714
cardiac septum development GO:0003279 59 0.714
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis GO:2000166 1 0.710
rho protein signal transduction GO:0007266 32 0.708
negative regulation of cell migration GO:0030336 59 0.707
renal vesicle induction GO:0072034 3 0.707
bone morphogenesis GO:0060349 78 0.702
cardiac cell fate specification GO:0060912 2 0.702
negative regulation of cartilage development GO:0061037 17 0.701
mesonephros development GO:0001823 97 0.701
branching involved in salivary gland morphogenesis GO:0060445 26 0.701
diencephalon development GO:0021536 63 0.696
respiratory tube development GO:0030323 167 0.695
positive regulation of bmp signaling pathway GO:0030513 23 0.688
positive regulation of cell migration GO:0030335 109 0.685
endoderm development GO:0007492 45 0.683
leukocyte differentiation GO:0002521 342 0.680
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.680
glial cell development GO:0021782 54 0.678
blood vessel morphogenesis GO:0048514 285 0.674
regulation of cellular component biogenesis GO:0044087 181 0.642
Mouse
regulation of cardiac muscle tissue growth GO:0055021 26 0.637
formation of primary germ layer GO:0001704 77 0.637
lung alveolus development GO:0048286 45 0.633
positive regulation of cell development GO:0010720 237 0.632
negative regulation of cell development GO:0010721 169 0.625
positive regulation of nervous system development GO:0051962 221 0.625
Mouse
negative regulation of wnt signaling pathway involved in heart development GO:0003308 4 0.618
skin development GO:0043588 220 0.616
stem cell maintenance GO:0019827 130 0.614
chondrocyte development GO:0002063 24 0.614
embryonic organ morphogenesis GO:0048562 276 0.612
positive regulation of growth GO:0045927 104 0.607
Mouse
embryonic skeletal system morphogenesis GO:0048704 91 0.602
exocrine system development GO:0035272 45 0.601
endocardial cell differentiation GO:0060956 4 0.594
positive regulation of transcription from rna polymerase ii promoter involved in smooth muscle cell differentiation GO:2000721 2 0.587
endoderm formation GO:0001706 20 0.584
regulation of neuron differentiation GO:0045664 281 0.581
striated muscle cell development GO:0055002 125 0.576
Worm
male sex differentiation GO:0046661 109 0.575
sensory perception GO:0007600 245 0.575
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.571
Worm
cell surface receptor signaling pathway involved in heart development GO:0061311 15 0.570
muscle tissue development GO:0060537 308 0.565
developmental induction GO:0031128 34 0.564
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.562
metanephros development GO:0001656 79 0.558
kidney epithelium development GO:0072073 121 0.555
regulation of bmp signaling pathway GO:0030510 60 0.553
heart valve development GO:0003170 23 0.549
nephron development GO:0072006 109 0.547
glial cell fate commitment GO:0021781 14 0.544
digestive system development GO:0055123 200 0.541
regulation of cell proliferation involved in heart morphogenesis GO:2000136 15 0.541
regulation of cardiac muscle tissue development GO:0055024 31 0.540
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.538
response to amino acid GO:0043200 37 0.537
negative regulation of bmp signaling pathway GO:0030514 35 0.533
tissue homeostasis GO:0001894 115 0.530
metanephric nephron morphogenesis GO:0072273 19 0.523
synaptic transmission GO:0007268 329 0.522
Mouse
neural crest cell migration GO:0001755 32 0.519
endodermal cell fate determination GO:0007493 2 0.514
neural tube patterning GO:0021532 43 0.513
negative regulation of neuron differentiation GO:0045665 101 0.512
lateral mesodermal cell differentiation GO:0048371 3 0.508
cardiac muscle tissue morphogenesis GO:0055008 44 0.507
cell fate commitment GO:0045165 210 0.493
positive regulation of cell motility GO:2000147 116 0.490
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.486
Mouse
embryonic limb morphogenesis GO:0030326 126 0.482
forebrain cell migration GO:0021885 58 0.481
ventricular septum morphogenesis GO:0060412 27 0.462
muscle fiber development GO:0048747 76 0.456
metanephric nephron development GO:0072210 34 0.451
embryonic digit morphogenesis GO:0042733 56 0.450
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.447
epithelial to mesenchymal transition GO:0001837 47 0.445
skeletal muscle fiber development GO:0048741 58 0.442
epithelial cell development GO:0002064 159 0.437
tendon cell differentiation GO:0035990 4 0.432
placenta development GO:0001890 140 0.432
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.431
small gtpase mediated signal transduction GO:0007264 97 0.426
collagen metabolic process GO:0032963 17 0.425
central nervous system vasculogenesis GO:0022009 3 0.421
regulation of planar cell polarity pathway involved in ventricular septum morphogenesis GO:2000148 1 0.417
gastrulation GO:0007369 116 0.416
semaphorin plexin signaling pathway involved in bone trabecula morphogenesis GO:1900220 2 0.413
nephron morphogenesis GO:0072028 69 0.410
regulation of muscle tissue development GO:1901861 97 0.409
smooth muscle cell migration GO:0014909 10 0.407
urogenital system development GO:0001655 261 0.407
extrinsic apoptotic signaling pathway GO:0097191 126 0.404
rac protein signal transduction GO:0016601 13 0.403
muscle tissue morphogenesis GO:0060415 53 0.402
digestive tract morphogenesis GO:0048546 147 0.402
prostate gland epithelium morphogenesis GO:0060740 31 0.399
neuron projection extension GO:1990138 64 0.397
negative regulation of neuron projection development GO:0010977 50 0.393
endodermal cell differentiation GO:0035987 14 0.392
lymphocyte differentiation GO:0030098 242 0.391
telencephalon development GO:0021537 186 0.388
intracellular protein transport GO:0006886 204 0.388
myeloid leukocyte differentiation GO:0002573 119 0.388
genitalia development GO:0048806 37 0.386
cell migration involved in gastrulation GO:0042074 13 0.383
detection of chemical stimulus involved in sensory perception of taste GO:0050912 3 0.380
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.377
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.376
negative regulation of chondrocyte differentiation GO:0032331 13 0.373
heart valve morphogenesis GO:0003179 21 0.373
positive regulation of bone resorption GO:0045780 13 0.370
primary neural tube formation GO:0014020 95 0.368
anterior commissure morphogenesis GO:0021960 6 0.366
neuroblast differentiation GO:0014016 2 0.364
osteoclast differentiation GO:0030316 62 0.360
regulation of rho protein signal transduction GO:0035023 71 0.359
Mouse
ear development GO:0043583 200 0.358
negative regulation of planar cell polarity pathway involved in heart morphogenesis GO:2000160 1 0.357
positive regulation of apoptotic process GO:0043065 217 0.355
Mouse
regulation of hydrolase activity GO:0051336 246 0.354
Mouse
signal transduction in absence of ligand GO:0038034 55 0.353
regulation of neuron projection development GO:0010975 169 0.353
ventricular septum development GO:0003281 42 0.350
embryonic heart tube development GO:0035050 65 0.348
regulation of apoptotic signaling pathway GO:2001233 197 0.345
angiogenesis GO:0001525 201 0.343
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.340
limb bud formation GO:0060174 10 0.338
molting cycle GO:0042303 90 0.337
Worm
aorta morphogenesis GO:0035909 22 0.333
embryonic heart tube morphogenesis GO:0003143 51 0.331
regulation of hippo signaling GO:0035330 1 0.330
regulation of cellular response to growth factor stimulus GO:0090287 82 0.328
cardiac muscle cell development GO:0055013 39 0.328
mitral valve morphogenesis GO:0003183 4 0.327
negative regulation of glial cell proliferation GO:0060253 4 0.325
endodermal cell fate specification GO:0001714 4 0.324
ear morphogenesis GO:0042471 118 0.323
morphogenesis of an epithelial fold GO:0060571 28 0.322
fibroblast growth factor receptor signaling pathway involved in mammary gland specification GO:0060595 2 0.322
regulation of neuron migration GO:2001222 22 0.321
pituitary gland development GO:0021983 38 0.321
outflow tract morphogenesis GO:0003151 53 0.320
placenta blood vessel development GO:0060674 31 0.320
atrioventricular valve morphogenesis GO:0003181 13 0.320
spinal cord development GO:0021510 81 0.319
response to fibroblast growth factor GO:0071774 47 0.316
renal tubule morphogenesis GO:0061333 72 0.316
extracellular matrix assembly GO:0085029 12 0.314
nephron tubule morphogenesis GO:0072078 68 0.313
cell aggregation GO:0098743 18 0.310
organelle localization GO:0051640 179 0.310
osteoblast proliferation GO:0033687 18 0.309
branching involved in ureteric bud morphogenesis GO:0001658 56 0.308
myeloid cell differentiation GO:0030099 233 0.308
positive regulation of ureteric bud formation GO:0072107 3 0.308
negative regulation of cell motility GO:2000146 61 0.308
neural tube development GO:0021915 160 0.307
positive regulation of bone remodeling GO:0046852 13 0.307
ribonucleotide metabolic process GO:0009259 291 0.305
Mouse
regulation of cell substrate adhesion GO:0010810 73 0.305
Mouse
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.302
cartilage development involved in endochondral bone morphogenesis GO:0060351 24 0.302
uterus morphogenesis GO:0061038 2 0.301
regulation of epithelial to mesenchymal transition GO:0010717 22 0.300
regulation of cardioblast differentiation GO:0051890 3 0.299
regulation of striated muscle cell differentiation GO:0051153 81 0.298
salivary gland morphogenesis GO:0007435 33 0.298
cardiac chamber development GO:0003205 108 0.297
membrane organization GO:0061024 245 0.295
Mouse
renal vesicle morphogenesis GO:0072077 15 0.294
branchiomotor neuron axon guidance GO:0021785 7 0.294
gonad development GO:0008406 141 0.293
lens morphogenesis in camera type eye GO:0002089 24 0.292
regulation of planar cell polarity pathway involved in outflow tract morphogenesis GO:2000163 1 0.292
mitral valve development GO:0003174 4 0.289
filopodium assembly GO:0046847 19 0.288
embryonic appendage morphogenesis GO:0035113 126 0.287
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.286
regulation of axon extension GO:0030516 43 0.285
substrate dependent cell migration GO:0006929 18 0.283
cardiac ventricle development GO:0003231 83 0.283
liver development GO:0001889 66 0.282
skeletal muscle cell differentiation GO:0035914 66 0.282
cell cell signaling involved in cell fate commitment GO:0045168 35 0.280
lung smooth muscle development GO:0061145 2 0.279
regulation of engulfment of apoptotic cell GO:1901074 2 0.278
trachea cartilage morphogenesis GO:0060535 4 0.273
negative regulation of photoreceptor cell differentiation GO:0046533 4 0.273
pallium development GO:0021543 120 0.272
odontogenesis of dentin containing tooth GO:0042475 66 0.271
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.271
bone resorption GO:0045453 38 0.270
regulation of organelle organization GO:0033043 289 0.269
negative regulation of mesodermal cell fate specification GO:0042662 3 0.268
body morphogenesis GO:0010171 45 0.266
Worm
regulation of myoblast differentiation GO:0045661 29 0.266
negative regulation of ras protein signal transduction GO:0046580 18 0.265
renal tubule development GO:0061326 87 0.264
negative regulation of osteoblast differentiation GO:0045668 30 0.263
cytoplasmic transport GO:0016482 234 0.261
cardiac atrium development GO:0003230 24 0.260
replacement ossification GO:0036075 26 0.260
cell junction assembly GO:0034329 52 0.259
Worm
positive regulation of protein modification process GO:0031401 299 0.258
Mouse
apoptotic process involved in morphogenesis GO:0060561 25 0.258
regulation of osteoblast differentiation GO:0045667 67 0.257
palate development GO:0060021 76 0.256
detection of stimulus involved in sensory perception GO:0050906 44 0.255
positive regulation of osteoblast proliferation GO:0033690 9 0.255
sympathetic nervous system development GO:0048485 22 0.252
glomerular epithelial cell development GO:0072310 6 0.251
endocardial cushion morphogenesis GO:0003203 18 0.251
engulfment of apoptotic cell GO:0043652 3 0.251
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 43 0.249
endodermal digestive tract morphogenesis GO:0061031 4 0.247
negative regulation of rho protein signal transduction GO:0035024 7 0.247
anatomical structure homeostasis GO:0060249 145 0.247
regulation of morphogenesis of a branching structure GO:0060688 53 0.246
smoothened signaling pathway GO:0007224 105 0.246
central nervous system neuron differentiation GO:0021953 162 0.243
metanephric glomerular basement membrane development GO:0072274 1 0.243
negative regulation of gastrulation GO:2000542 3 0.243
regulation of organ morphogenesis GO:2000027 144 0.240
cerebellar granule cell precursor tangential migration GO:0021935 1 0.239
epithelial tube formation GO:0072175 130 0.238
positive regulation of inner ear receptor cell differentiation GO:2000982 1 0.237
calcium ion transport GO:0006816 159 0.235
morphogenesis of an epithelial sheet GO:0002011 27 0.235
negative regulation of cell proliferation GO:0008285 296 0.234
multicellular organismal homeostasis GO:0048871 164 0.234
telencephalon cell migration GO:0022029 55 0.234
septum primum development GO:0003284 4 0.232
retinal ganglion cell axon guidance GO:0031290 18 0.231
renal system development GO:0072001 225 0.231
fat cell differentiation GO:0045444 160 0.231
muscle cell migration GO:0014812 19 0.230
cardiac chamber morphogenesis GO:0003206 93 0.230
ribonucleotide catabolic process GO:0009261 208 0.229
Mouse
cellular response to amino acid stimulus GO:0071230 29 0.224
multicellular organismal macromolecule metabolic process GO:0044259 19 0.223
retina vasculature development in camera type eye GO:0061298 17 0.223
positive regulation of lens epithelial cell proliferation GO:2001111 1 0.219
mapk cascade GO:0000165 281 0.218
nephron epithelium development GO:0072009 92 0.218
regulation of ras protein signal transduction GO:0046578 114 0.217
Mouse
homeostasis of number of cells GO:0048872 210 0.217
bmp signaling pathway GO:0030509 93 0.217
purine nucleoside metabolic process GO:0042278 241 0.216
Mouse
central nervous system neuron development GO:0021954 67 0.216
development of primary sexual characteristics GO:0045137 143 0.215
morphogenesis of a polarized epithelium GO:0001738 37 0.214
somitogenesis GO:0001756 69 0.213
regulation of endodermal cell differentiation GO:1903224 2 0.211
aorta development GO:0035904 23 0.209
central nervous system projection neuron axonogenesis GO:0021952 21 0.205
central nervous system neuron axonogenesis GO:0021955 28 0.205
regulation of exocytosis GO:0017157 61 0.204
negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis GO:2000164 1 0.203
ameboidal type cell migration GO:0001667 128 0.201
protein targeting GO:0006605 143 0.201
regulation of cellular amine metabolic process GO:0033238 20 0.200
nephron tubule development GO:0072080 84 0.199
autonomic nervous system development GO:0048483 43 0.198
mesonephric tubule development GO:0072164 94 0.198
negative regulation of cell fate specification GO:0009996 4 0.198
carbohydrate derivative catabolic process GO:1901136 231 0.198
Mouse
positive regulation of ossification GO:0045778 47 0.197
regulation of cell projection organization GO:0031344 206 0.195
ventricular trabecula myocardium morphogenesis GO:0003222 11 0.195
trunk neural crest cell migration GO:0036484 4 0.194
positive regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:0035793 1 0.191
negative regulation of smooth muscle cell migration GO:0014912 2 0.190
bone mineralization GO:0030282 54 0.189
peripheral nervous system development GO:0007422 53 0.188
single organism cell adhesion GO:0098602 156 0.187
regulation of intracellular transport GO:0032386 159 0.187
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.186
hindbrain tangential cell migration GO:0021934 2 0.186
muscle cell development GO:0055001 133 0.186
Worm
response to epidermal growth factor GO:0070849 4 0.186
lung induction GO:0060492 3 0.185
epithelial cell proliferation GO:0050673 174 0.185
ascending aorta morphogenesis GO:0035910 3 0.183
retina morphogenesis in camera type eye GO:0060042 45 0.183
microglia development GO:0014005 2 0.183
determination of heart left right asymmetry GO:0061371 48 0.182
tissue migration GO:0090130 68 0.182
regulation of cytoskeleton organization GO:0051493 122 0.180
schwann cell development GO:0014044 22 0.179
endothelium development GO:0003158 45 0.178
heart formation GO:0060914 16 0.178
developmental growth involved in morphogenesis GO:0060560 138 0.177
glial cell migration GO:0008347 7 0.175
regulation of vesicle mediated transport GO:0060627 139 0.171
regeneration GO:0031099 38 0.171
cell proliferation in hindbrain GO:0021534 10 0.170
cerebral cortex development GO:0021987 86 0.168
establishment or maintenance of cell polarity GO:0007163 86 0.167
ventricular cardiac muscle tissue morphogenesis GO:0055010 32 0.167
cell substrate junction assembly GO:0007044 24 0.167
Worm
retinal rod cell differentiation GO:0060221 2 0.167
retina vasculature morphogenesis in camera type eye GO:0061299 10 0.167
epithelial tube branching involved in lung morphogenesis GO:0060441 28 0.166
positive regulation of extracellular matrix organization GO:1903055 4 0.164
endothelial cell migration GO:0043542 44 0.164
response to transforming growth factor beta GO:0071559 88 0.164
closure of optic fissure GO:0061386 2 0.164
negative regulation of cellular component organization GO:0051129 194 0.163
embryonic heart tube formation GO:0003144 1 0.163
foregut morphogenesis GO:0007440 12 0.163
development of primary male sexual characteristics GO:0046546 88 0.163
neural crest cell differentiation GO:0014033 54 0.162
male gonad development GO:0008584 88 0.162
intestinal epithelial structure maintenance GO:0060729 4 0.161
skin morphogenesis GO:0043589 38 0.160
midbrain hindbrain boundary maturation GO:0021732 1 0.160
epidermal growth factor receptor signaling pathway GO:0007173 28 0.160
Worm
regulation of smad protein import into nucleus GO:0060390 3 0.158
prostate gland morphogenetic growth GO:0060737 4 0.158
inner cell mass cellular morphogenesis GO:0001828 1 0.157
response to organonitrogen compound GO:0010243 246 0.157
divalent inorganic cation transport GO:0072511 178 0.156
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.156
oligodendrocyte differentiation GO:0048709 53 0.155
mesodermal cell migration GO:0008078 4 0.154
negative regulation of nervous system development GO:0051961 156 0.154
cardiogenic plate morphogenesis GO:0003142 1 0.153
frontal suture morphogenesis GO:0060364 2 0.153
tube closure GO:0060606 91 0.153
atrial septum primum morphogenesis GO:0003289 3 0.152
neuroblast proliferation GO:0007405 49 0.152
mesenchyme development GO:0060485 152 0.151
regulation of heart morphogenesis GO:2000826 22 0.150
wnt signaling pathway involved in heart development GO:0003306 8 0.150
regulation of ureteric bud formation GO:0072106 3 0.150
determination of left right symmetry GO:0007368 80 0.150
sensory perception of chemical stimulus GO:0007606 51 0.149
positive regulation of epidermal cell differentiation GO:0045606 6 0.148
regulation of cation channel activity GO:2001257 22 0.148
tissue remodeling GO:0048771 102 0.148
regulation of organ formation GO:0003156 34 0.147
protein localization to membrane GO:0072657 108 0.147
Mouse
cell maturation GO:0048469 127 0.146
lung field specification GO:0060424 3 0.145
smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation GO:0021938 4 0.144
ribose phosphate metabolic process GO:0019693 291 0.144
Mouse
regulation of heart growth GO:0060420 31 0.143
mesoderm development GO:0007498 100 0.143
microtubule cytoskeleton organization GO:0000226 157 0.142
cellular amine metabolic process GO:0044106 44 0.141
epidermis development GO:0008544 187 0.141
regulation of secretion GO:0051046 274 0.141
erbb signaling pathway GO:0038127 32 0.140
Worm
neuroblast fate commitment GO:0014017 1 0.139
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.139
regulation of cell activation GO:0050865 289 0.139
circulatory system process GO:0003013 197 0.139
regulation of cell growth GO:0001558 91 0.138
epidermis morphogenesis GO:0048730 33 0.138
endocardial cushion formation GO:0003272 13 0.137
positive regulation of cell projection organization GO:0031346 95 0.137
axon ensheathment GO:0008366 76 0.136
biomineral tissue development GO:0031214 64 0.136
hepaticobiliary system development GO:0061008 67 0.135
lateral mesoderm morphogenesis GO:0048369 3 0.135
positive regulation of epithelial cell migration GO:0010634 19 0.135
endothelial cell differentiation GO:0045446 41 0.135
positive regulation of stem cell proliferation GO:2000648 59 0.135
cardiac ventricle morphogenesis GO:0003208 50 0.134
hair follicle development GO:0001942 85 0.134
regulation of extracellular matrix assembly GO:1901201 2 0.133
apoptotic signaling pathway GO:0097190 306 0.133
alcohol metabolic process GO:0006066 116 0.132
detection of stimulus GO:0051606 84 0.131
epithelial cell morphogenesis GO:0003382 41 0.131
positive regulation of metanephric mesenchymal cell migration GO:2000591 1 0.131
regulation of cellular amino acid metabolic process GO:0006521 5 0.130
cation homeostasis GO:0055080 212 0.129
epithelial cell migration GO:0010631 63 0.129
rostrocaudal neural tube patterning GO:0021903 12 0.129
glomerular visceral epithelial cell development GO:0072015 6 0.129
purine nucleoside catabolic process GO:0006152 205 0.128
Mouse
actin cytoskeleton organization GO:0030036 220 0.128
Worm
negative regulation of embryonic development GO:0045992 22 0.128
odontogenesis GO:0042476 78 0.127
left right pattern formation GO:0060972 23 0.127
regulation of proteolysis GO:0030162 164 0.127
neuroblast fate determination GO:0007400 1 0.127
epithelial cell proliferation involved in prostate gland development GO:0060767 11 0.125
regulation of mesodermal cell fate specification GO:0042661 5 0.124
endocardial cushion to mesenchymal transition involved in heart valve formation GO:0003199 4 0.124
cardiac epithelial to mesenchymal transition GO:0060317 18 0.124
ureteric bud development GO:0001657 94 0.124
wnt signaling pathway involved in somitogenesis GO:0090244 4 0.123
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.123
Mouse
compound eye development GO:0048749 1 0.123
cell cell junction organization GO:0045216 72 0.123
nucleoside catabolic process GO:0009164 206 0.123
Mouse
hindbrain formation GO:0021576 1 0.121
stem cell proliferation GO:0072089 117 0.121

Hspg2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.996
musculoskeletal system disease DOID:17 0 0.996
connective tissue disease DOID:65 0 0.986
muscular disease DOID:0080000 0 0.681
myopathy DOID:423 0 0.637
muscle tissue disease DOID:66 0 0.637
bone remodeling disease DOID:0080005 0 0.554
bone disease DOID:0080001 0 0.554
osteochondrodysplasia DOID:2256 0 0.473
bone development disease DOID:0080006 0 0.473
muscular dystrophy DOID:9884 0 0.245
congenital muscular dystrophy DOID:0050557 0 0.164