IMP
Process View
limb bud formation
The process pertaining to the initial formation of a limb bud from unspecified parts. This process begins with the formation of a local condensation of mesenchyme cells within the prospective limb field, and ends when a limb bud is recognizable.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "limb bud formation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Fgfr2 | fibroblast growth factor receptor 2 | 1.000 | ||
| Gli3 | GLI-Kruppel family member GLI3 | 1.000 | ||
| Shh | sonic hedgehog | 1.000 | ||
| Fgfr3 | fibroblast growth factor receptor 3 | 0.967 | Mouse | |
| Col1a1 | collagen, type I, alpha 1 | 0.967 | Mouse | |
| Fgf10 | fibroblast growth factor 10 | 0.957 | ||
| Gli2 | GLI-Kruppel family member GLI2 | 0.935 | ||
| Arhgef11 | Rho guanine nucleotide exchange factor (GEF) 11 | 0.882 | ||
| Sox9 | SRY-box containing gene 9 | 0.864 | ||
| Col3a1 | collagen, type III, alpha 1 | 0.853 | Mouse | |
| Meox2 | mesenchyme homeobox 2 | 0.698 | ||
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.658 | ||
| Nog | noggin | 0.605 | ||
| Pax2 | paired box gene 2 | 0.572 | ||
| Col5a2 | collagen, type V, alpha 2 | 0.551 | Mouse | |
| Col6a2 | collagen, type VI, alpha 2 | 0.548 | ||
| Bmp4 | bone morphogenetic protein 4 | 0.519 | ||
| Tbx3 | T-box 3 | 0.509 | ||
| Col6a1 | collagen, type VI, alpha 1 | 0.495 | ||
| Tcf21 | transcription factor 21 | 0.466 | ||
| Sema6a | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.449 | ||
| Serpinh1 | serine (or cysteine) peptidase inhibitor, clade H, member 1 | 0.399 | ||
| Sox11 | SRY-box containing gene 11 | 0.388 | ||
| Col2a1 | collagen, type II, alpha 1 | 0.347 | ||
| Hspg2 | perlecan (heparan sulfate proteoglycan 2) | 0.338 | ||
| Prrx1 | paired related homeobox 1 | 0.318 | ||
| Sox18 | SRY-box containing gene 18 | 0.314 | Mouse | |
| Pax3 | paired box gene 3 | 0.313 | ||
| Rarb | retinoic acid receptor, beta | 0.297 | ||
| Sox4 | SRY-box containing gene 4 | 0.284 | ||
| Col1a2 | collagen, type I, alpha 2 | 0.182 | Mouse | |
| Sall4 | sal-like 4 (Drosophila) | 0.174 | ||
| Rarg | retinoic acid receptor, gamma | 0.169 | ||
| Prrx2 | paired related homeobox 2 | 0.166 | ||
| Tcfap2a | transcription factor AP-2, alpha | 0.164 | ||
| Twist2 | twist homolog 2 (Drosophila) | 0.160 | ||
| Col5a1 | collagen, type V, alpha 1 | 0.155 | Mouse | |
| Sox2 | SRY-box containing gene 2 | 0.148 | Mouse | |
| Pthlh | parathyroid hormone-like peptide | 0.148 | ||
| Alx4 | aristaless-like homeobox 4 | 0.137 | ||
| Epha4 | Eph receptor A4 | 0.132 | ||
| Col11a1 | collagen, type XI, alpha 1 | 0.132 | Mouse | |
| Pou5f1 | POU domain, class 5, transcription factor 1 | 0.126 | ||
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.124 | ||
| Ret | ret proto-oncogene | 0.122 | ||
| Fgf9 | fibroblast growth factor 9 | 0.119 | Mouse | |
| Pou3f3 | POU domain, class 3, transcription factor 3 | 0.117 | ||
| Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 0.116 | ||
| Wnt5a | wingless-related MMTV integration site 5A | 0.110 | ||
| Postn | periostin, osteoblast specific factor | 0.106 | ||
| Nrp1 | neuropilin 1 | 0.102 | ||
| Col15a1 | collagen, type XV, alpha 1 | 0.102 | ||
| Col6a3 | collagen, type VI, alpha 3 | 0.099 | ||
| Fgf8 | fibroblast growth factor 8 | 0.098 | ||
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.091 | ||
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.084 | ||
| She | src homology 2 domain-containing transforming protein E | 0.083 | ||
| Acan | aggrecan | 0.083 | ||
| Matn4 | matrilin 4 | 0.078 | ||
| Ror1 | receptor tyrosine kinase-like orphan receptor 1 | 0.078 | ||
| Hoxd11 | homeobox D11 | 0.073 | ||
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.073 | ||
| Bmp5 | bone morphogenetic protein 5 | 0.071 | ||
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.070 | ||
| Nrp2 | neuropilin 2 | 0.070 | ||
| Hoxd13 | homeobox D13 | 0.066 | ||
| Nes | nestin | 0.052 | ||
| Col4a2 | collagen, type IV, alpha 2 | 0.052 | ||
| Aplnr | apelin receptor | 0.052 | ||
| Cldn5 | claudin 5 | 0.052 | ||
| Tgfb2 | transforming growth factor, beta 2 | 0.051 | ||
| Sox7 | SRY-box containing gene 7 | 0.051 | Mouse | |
| Tbx15 | T-box 15 | 0.050 | ||
| Grb10 | growth factor receptor bound protein 10 | 0.050 | ||
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.050 | ||
| Sox17 | SRY-box containing gene 17 | 0.049 | Mouse | |
| Gli1 | GLI-Kruppel family member GLI1 | 0.048 | ||
| Arhgef12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.046 | ||
| Efnb2 | ephrin B2 | 0.045 | ||
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.044 | ||
| Fstl1 | follistatin-like 1 | 0.044 | ||
| Scn5a | sodium channel, voltage-gated, type V, alpha | 0.044 | ||
| Btbd17 | BTB (POZ) domain containing 17 | 0.043 | ||
| Cacna2d1 | calcium channel, voltage-dependent, alpha2/delta subunit 1 | 0.043 | ||
| Ceacam16 | carcinoembryonic antigen-related cell adhesion molecule 16 | 0.043 | ||
| Pcsk5 | proprotein convertase subtilisin/kexin type 5 | 0.040 | ||
| Nkx2-1 | NK2 homeobox 1 | 0.040 | ||
| Gata4 | GATA binding protein 4 | 0.040 | ||
| Angpt4 | angiopoietin 4 | 0.039 | ||
| Gata6 | GATA binding protein 6 | 0.038 | ||
| Nodal | nodal | 0.037 | ||
| Smad3 | MAD homolog 3 (Drosophila) | 0.036 | ||
| Ednra | endothelin receptor type A | 0.035 | ||
| Edn3 | endothelin 3 | 0.034 | ||
| Smo | smoothened homolog (Drosophila) | 0.033 | ||
| Ptprb | protein tyrosine phosphatase, receptor type, B | 0.033 | ||
| Wnt9b | wingless-type MMTV integration site 9B | 0.032 | ||
| Ptch2 | patched homolog 2 | 0.032 | ||
| Capn6 | calpain 6 | 0.032 | ||
| Bcl6b | B-cell CLL/lymphoma 6, member B | 0.032 | ||
| Foxf1a | forkhead box F1a | 0.031 | ||
| Snai1 | snail homolog 1 (Drosophila) | 0.031 | ||
| Nr0b1 | nuclear receptor subfamily 0, group B, member 1 | 0.031 | ||
| Col8a1 | collagen, type VIII, alpha 1 | 0.030 | ||
| Fzd1 | frizzled homolog 1 (Drosophila) | 0.030 | ||
| Sparc | secreted acidic cysteine rich glycoprotein | 0.029 | ||
| Plxna1 | plexin A1 | 0.029 | Mouse | |
| Rara | retinoic acid receptor, alpha | 0.029 | ||
| Fgf3 | fibroblast growth factor 3 | 0.029 | Mouse | |
| Hoxa11 | homeobox A11 | 0.029 | ||
| Col4a1 | collagen, type IV, alpha 1 | 0.029 | ||
| Lmx1a | LIM homeobox transcription factor 1 alpha | 0.028 | ||
| Ar | androgen receptor | 0.027 | ||
| Tmeff2 | transmembrane protein with EGF-like and two follistatin-like domains 2 | 0.027 | ||
| Sdc3 | syndecan 3 | 0.027 | ||
| Crhr2 | corticotropin releasing hormone receptor 2 | 0.027 | ||
| Mmp16 | matrix metallopeptidase 16 | 0.026 | ||
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.026 | ||
| Bgn | biglycan | 0.026 | ||
| Col4a5 | collagen, type IV, alpha 5 | 0.026 | ||
| Wisp1 | WNT1 inducible signaling pathway protein 1 | 0.025 | ||
| Atp2b2 | ATPase, Ca++ transporting, plasma membrane 2 | 0.024 | ||
| Hoxa13 | homeobox A13 | 0.024 | ||
| Nf1 | neurofibromatosis 1 | 0.024 | ||
| Tbx2 | T-box 2 | 0.024 | ||
| Vegfa | vascular endothelial growth factor A | 0.024 | ||
| Ebf3 | early B-cell factor 3 | 0.024 | ||
| Chrd | chordin | 0.024 | ||
| Igdcc3 | immunoglobulin superfamily, DCC subclass, member 3 | 0.023 | ||
| Wnt6 | wingless-related MMTV integration site 6 | 0.023 | ||
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.022 | ||
| Ptch1 | patched homolog 1 | 0.022 | ||
| Nkx2-3 | NK2 transcription factor related, locus 3 (Drosophila) | 0.022 | ||
| Dnajb5 | DnaJ (Hsp40) homolog, subfamily B, member 5 | 0.022 | ||
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.022 | ||
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.021 | ||
| Sall1 | sal-like 1 (Drosophila) | 0.021 | ||
| Meox1 | mesenchyme homeobox 1 | 0.021 | ||
| Chrm4 | cholinergic receptor, muscarinic 4 | 0.021 | ||
| Dhh | desert hedgehog | 0.021 | Mouse | |
| Shc3 | src homology 2 domain-containing transforming protein C3 | 0.020 | ||
| Alx3 | aristaless-like homeobox 3 | 0.020 | ||
| Mrc2 | mannose receptor, C type 2 | 0.020 | ||
| Bmp1 | bone morphogenetic protein 1 | 0.019 | ||
| Sufu | suppressor of fused homolog (Drosophila) | 0.019 | ||
| Trp63 | transformation related protein 63 | 0.019 | ||
| Foxc1 | forkhead box C1 | 0.019 | ||
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.018 | ||
| Atoh7 | atonal homolog 7 (Drosophila) | 0.018 | ||
| Tie1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 0.018 | ||
| Btbd3 | BTB (POZ) domain containing 3 | 0.018 | ||
| Kdr | kinase insert domain protein receptor | 0.018 | ||
| Fzd9 | frizzled homolog 9 (Drosophila) | 0.018 | ||
| Col13a1 | collagen, type XIII, alpha 1 | 0.018 | ||
| Axin2 | axin2 | 0.018 | ||
| Tbx10 | T-box 10 | 0.017 | ||
| Smpd3 | sphingomyelin phosphodiesterase 3, neutral | 0.017 | ||
| Efna2 | ephrin A2 | 0.017 | ||
| Nkx3-2 | NK3 homeobox 2 | 0.017 | ||
| Bmp7 | bone morphogenetic protein 7 | 0.017 | ||
| Npr3 | natriuretic peptide receptor 3 | 0.016 | ||
| Runx2 | runt related transcription factor 2 | 0.016 | ||
| Sema6d | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D | 0.016 | ||
| Mmp17 | matrix metallopeptidase 17 | 0.016 | ||
| Pou3f4 | POU domain, class 3, transcription factor 4 | 0.016 | ||
| Gh | growth hormone | 0.015 | ||
| Apln | apelin | 0.015 | ||
| Tcf15 | transcription factor 15 | 0.015 | ||
| Efs | embryonal Fyn-associated substrate | 0.015 | ||
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.015 | ||
| Rgnef | Rho-guanine nucleotide exchange factor | 0.015 | ||
| Gdf11 | growth differentiation factor 11 | 0.015 | ||
| Ednrb | endothelin receptor type B | 0.015 | ||
| Egfr | epidermal growth factor receptor | 0.014 | ||
| Npr2 | natriuretic peptide receptor 2 | 0.014 | ||
| Plcb1 | phospholipase C, beta 1 | 0.014 | ||
| Cdh5 | cadherin 5 | 0.014 | ||
| Cd34 | CD34 antigen | 0.014 | ||
| Hhex | hematopoietically expressed homeobox | 0.014 | ||
| Sema3a | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.013 | ||
| Col14a1 | collagen, type XIV, alpha 1 | 0.013 | ||
| Rgs5 | regulator of G-protein signaling 5 | 0.013 | ||
| Myl2 | myosin, light polypeptide 2, regulatory, cardiac, slow | 0.013 | ||
| Adra2a | adrenergic receptor, alpha 2a | 0.013 | ||
| Ihh | Indian hedgehog | 0.013 | Mouse | |
| Hoxa5 | homeobox A5 | 0.013 | ||
| Lama4 | laminin, alpha 4 | 0.013 | ||
| Clcnka | chloride channel Ka | 0.012 | ||
| Dmrt1 | doublesex and mab-3 related transcription factor 1 | 0.012 | ||
| Tecta | tectorin alpha | 0.012 | ||
| Pkdcc | protein kinase domain containing, cytoplasmic | 0.012 | ||
| Dlx5 | distal-less homeobox 5 | 0.012 | ||
| Edar | ectodysplasin-A receptor | 0.012 | ||
| Bdkrb2 | bradykinin receptor, beta 2 | 0.012 | ||
| Pdgfb | platelet derived growth factor, B polypeptide | 0.012 | ||
| Epha1 | Eph receptor A1 | 0.012 | ||
| Tgfb1i1 | transforming growth factor beta 1 induced transcript 1 | 0.012 | ||
| Tspan9 | tetraspanin 9 | 0.012 | ||
| Hapln1 | hyaluronan and proteoglycan link protein 1 | 0.012 | ||
| Lef1 | lymphoid enhancer binding factor 1 | 0.012 | ||
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.012 | ||
| Eng | endoglin | 0.012 | ||
| Emcn | endomucin | 0.012 | ||
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.012 | ||
| Gabrd | gamma-aminobutyric acid (GABA) A receptor, subunit delta | 0.012 | ||
| Cdh11 | cadherin 11 | 0.011 | ||
| Fscn1 | fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus) | 0.011 | ||
| Tnc | tenascin C | 0.011 | ||
| Hoxb3 | homeobox B3 | 0.011 | ||
| Lhx3 | LIM homeobox protein 3 | 0.011 | ||
| Fbln2 | fibulin 2 | 0.011 | ||
| Npas1 | neuronal PAS domain protein 1 | 0.011 | ||
| Zbtb46 | zinc finger and BTB domain containing 46 | 0.011 | ||
| Gbx2 | gastrulation brain homeobox 2 | 0.011 | ||
| Itih1 | inter-alpha trypsin inhibitor, heavy chain 1 | 0.011 | ||
| Mest | mesoderm specific transcript | 0.010 | ||
| Adrb1 | adrenergic receptor, beta 1 | 0.010 | ||
| Sult4a1 | sulfotransferase family 4A, member 1 | 0.010 | ||
| Pcdh18 | protocadherin 18 | 0.010 | ||
| Ddr2 | discoidin domain receptor family, member 2 | 0.010 |