IMP

Process View

Mus musculus

2 genes annotated in mouse

Multi-species View

retinal rod cell differentiation

GO:0060221

The process in which a relatively unspecialized cell acquires the specialized features of a retinal rod cell.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "retinal rod cell differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "retinal rod cell differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
Shh	sonic hedgehog	0.999
Gli3	GLI-Kruppel family member GLI3	0.999
Fgfr2	fibroblast growth factor receptor 2	0.999
Pax3	paired box gene 3	0.995
Isl1	ISL1 transcription factor, LIM/homeodomain	0.983
Bmp4	bone morphogenetic protein 4	0.980
Pitx2	paired-like homeodomain transcription factor 2	0.965
Fgf8	fibroblast growth factor 8	0.961
Foxc1	forkhead box C1	0.960
Msx1	homeobox, msh-like 1	0.945
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.933
Otx2	orthodenticle homolog 2 (Drosophila)	0.932
Tcfap2a	transcription factor AP-2, alpha	0.911
Meox2	mesenchyme homeobox 2	0.902
Sox2	SRY-box containing gene 2	0.897	Mouse
Pax2	paired box gene 2	0.881
Tgfb2	transforming growth factor, beta 2	0.842
Foxc2	forkhead box C2	0.796
Pax6	paired box gene 6	0.773	Zebrafish
Eya1	eyes absent 1 homolog (Drosophila)	0.763
Sox4	SRY-box containing gene 4	0.756	Mouse
Ednra	endothelin receptor type A	0.683
Fgf10	fibroblast growth factor 10	0.653
Gli2	GLI-Kruppel family member GLI2	0.607
Chd7	chromodomain helicase DNA binding protein 7	0.560
Fgfr1	fibroblast growth factor receptor 1	0.553
Jag1	jagged 1	0.539
Zeb1	zinc finger E-box binding homeobox 1	0.460
Ctnnb1	catenin (cadherin associated protein), beta 1	0.460
Efnb2	ephrin B2	0.457
Smo	smoothened homolog (Drosophila)	0.456
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.455
Gbx2	gastrulation brain homeobox 2	0.436
Foxg1	forkhead box G1	0.427
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.382
Fgfr3	fibroblast growth factor receptor 3	0.377
Sox11	SRY-box containing gene 11	0.367	Mouse
Rarg	retinoic acid receptor, gamma	0.358
Nf1	neurofibromatosis 1	0.341
Tbx1	T-box 1	0.339
Vangl2	vang-like 2 (van gogh, Drosophila)	0.335
Ntf3	neurotrophin 3	0.321
Emx1	empty spiracles homolog 1 (Drosophila)	0.317
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.314
Hand1	heart and neural crest derivatives expressed transcript 1	0.298
Gata4	GATA binding protein 4	0.293
Nog	noggin	0.279
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.269
Rarb	retinoic acid receptor, beta	0.257
Hes1	hairy and enhancer of split 1 (Drosophila)	0.253
Hand2	heart and neural crest derivatives expressed transcript 2	0.251
Prrx1	paired related homeobox 1	0.233
Sox9	SRY-box containing gene 9	0.231
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.226
Vegfa	vascular endothelial growth factor A	0.226
Ptprb	protein tyrosine phosphatase, receptor type, B	0.197
Col2a1	collagen, type II, alpha 1	0.187
Otx1	orthodenticle homolog 1 (Drosophila)	0.177
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.167
Emx2	empty spiracles homolog 2 (Drosophila)	0.159
Ret	ret proto-oncogene	0.154
Bmp7	bone morphogenetic protein 7	0.144
Hoxa1	homeobox A1	0.139
Lmx1b	LIM homeobox transcription factor 1 beta	0.133
Rb1	retinoblastoma 1	0.133
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.129
Bmper	BMP-binding endothelial regulator	0.128
Trp53	transformation related protein 53	0.126
Fgf3	fibroblast growth factor 3	0.117
Alx4	aristaless-like homeobox 4	0.113
Rxra	retinoid X receptor alpha	0.106
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.095
Trp63	transformation related protein 63	0.094
Pitx1	paired-like homeodomain transcription factor 1	0.093
Hes5	hairy and enhancer of split 5 (Drosophila)	0.081
Nos3	nitric oxide synthase 3, endothelial cell	0.080
She	src homology 2 domain-containing transforming protein E	0.079
Rara	retinoic acid receptor, alpha	0.075
Tie1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.072
Prrx2	paired related homeobox 2	0.072
Sall4	sal-like 4 (Drosophila)	0.071
Ptch1	patched homolog 1	0.069
Hesx1	homeobox gene expressed in ES cells	0.068
Col1a1	collagen, type I, alpha 1	0.067
Pou5f1	POU domain, class 5, transcription factor 1	0.067
Egfr	epidermal growth factor receptor	0.061
Atoh7	atonal homolog 7 (Drosophila)	0.061
Sox17	SRY-box containing gene 17	0.060	Mouse
Tcfap2c	transcription factor AP-2, gamma	0.059
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.055
Twist2	twist homolog 2 (Drosophila)	0.054
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.052
Dlx5	distal-less homeobox 5	0.052
Gdnf	glial cell line derived neurotrophic factor	0.052
Msx2	homeobox, msh-like 2	0.052
Tbx2	T-box 2	0.051
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.050
Tbx3	T-box 3	0.049
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.048
Sfrp2	secreted frizzled-related protein 2	0.046
Foxi3	forkhead box I3	0.046
Kit	kit oncogene	0.044
Pbx1	pre B-cell leukemia transcription factor 1	0.042
Gata3	GATA binding protein 3	0.041
Sall3	sal-like 3 (Drosophila)	0.040
Gas1	growth arrest specific 1	0.039
Meox1	mesenchyme homeobox 1	0.039
Aplnr	apelin receptor	0.039
Alx3	aristaless-like homeobox 3	0.039
Ednrb	endothelin receptor type B	0.038
Lrp2	low density lipoprotein receptor-related protein 2	0.037
Lef1	lymphoid enhancer binding factor 1	0.037
Hoxa3	homeobox A3	0.036
Cldn5	claudin 5	0.036
Pten	phosphatase and tensin homolog	0.035
Wnt3a	wingless-related MMTV integration site 3A	0.035
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.034
Tbx15	T-box 15	0.034
Hoxd13	homeobox D13	0.033
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.033
Lhx3	LIM homeobox protein 3	0.033
Gata6	GATA binding protein 6	0.033
Zic3	zinc finger protein of the cerebellum 3	0.032
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.031
Bdnf	brain derived neurotrophic factor	0.031
Hoxa5	homeobox A5	0.031
Pthlh	parathyroid hormone-like peptide	0.030
Smad6	MAD homolog 6 (Drosophila)	0.030
Pkd1	polycystic kidney disease 1 homolog	0.029
Lhx1	LIM homeobox protein 1	0.028
Wnt5a	wingless-related MMTV integration site 5A	0.027
Apc	adenomatosis polyposis coli	0.027
Mesp1	mesoderm posterior 1	0.027
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.026
Sox18	SRY-box containing gene 18	0.026	Mouse
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.026
Kdr	kinase insert domain protein receptor	0.026
Wt1	Wilms tumor 1 homolog	0.026
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.025
Eda	ectodysplasin-A	0.025
Pax1	paired box gene 1	0.025
Insm1	insulinoma-associated 1	0.025
Notch3	Notch gene homolog 3 (Drosophila)	0.025
Matn4	matrilin 4	0.025
Tcf15	transcription factor 15	0.024
Phox2b	paired-like homeobox 2b	0.024
Neurod1	neurogenic differentiation 1	0.024
Kitl	kit ligand	0.024
Tbx10	T-box 10	0.024
Gsc	goosecoid homeobox	0.024
Foxf2	forkhead box F2	0.023
Nodal	nodal	0.023
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.023
Bcl6b	B-cell CLL/lymphoma 6, member B	0.023
Chrd	chordin	0.023
Mitf	microphthalmia-associated transcription factor	0.022
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.022
Hoxa2	homeobox A2	0.022
Pou4f2	POU domain, class 4, transcription factor 2	0.022
Arx	aristaless related homeobox	0.021
Wnt6	wingless-related MMTV integration site 6	0.021
Sox7	SRY-box containing gene 7	0.021	Mouse
Fgf4	fibroblast growth factor 4	0.021
Lrp6	low density lipoprotein receptor-related protein 6	0.021
Hmga2	high mobility group AT-hook 2	0.021
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.020
Emcn	endomucin	0.020
Gpc3	glypican 3	0.020
Nanog	Nanog homeobox	0.019
Ebf3	early B-cell factor 3	0.019
Twist1	twist homolog 1 (Drosophila)	0.019
Ptk7	PTK7 protein tyrosine kinase 7	0.019
Hoxb13	homeobox B13	0.019
Krt14	keratin 14	0.018
Lmx1a	LIM homeobox transcription factor 1 alpha	0.018
Bmp5	bone morphogenetic protein 5	0.018
En1	engrailed 1	0.018
Nkx6-1	NK6 homeobox 1	0.018
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.018
Gja4	gap junction protein, alpha 4	0.018
Neurog2	neurogenin 2	0.018
Tcf21	transcription factor 21	0.018
Alx1	ALX homeobox 1	0.018
Podxl	podocalyxin-like	0.017
Sfn	stratifin	0.017
Efna2	ephrin A2	0.017
Foxf1a	forkhead box F1a	0.017
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.017
Col11a1	collagen, type XI, alpha 1	0.016
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.016
Ldb2	LIM domain binding 2	0.016
Dll1	delta-like 1 (Drosophila)	0.016
Phox2a	paired-like homeobox 2a	0.016
Acvr1	activin A receptor, type 1	0.016
Lhx5	LIM homeobox protein 5	0.016
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.015
Bmp2	bone morphogenetic protein 2	0.015
En2	engrailed 2	0.015
Pou3f1	POU domain, class 3, transcription factor 1	0.015
Fgf18	fibroblast growth factor 18	0.015
Hhex	hematopoietically expressed homeobox	0.015
Gli1	GLI-Kruppel family member GLI1	0.015
Tgfbr2	transforming growth factor, beta receptor II	0.015
Efs	embryonal Fyn-associated substrate	0.015
Ephb2	Eph receptor B2	0.015
Gja1	gap junction protein, alpha 1	0.015
Pcdh12	protocadherin 12	0.015
Irx5	Iroquois related homeobox 5 (Drosophila)	0.015
Krt17	keratin 17	0.015
Bnc1	basonuclin 1	0.014
Emid2	EMI domain containing 2	0.014
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.014
Edar	ectodysplasin-A receptor	0.014
Hoxb3	homeobox B3	0.013
Pou3f3	POU domain, class 3, transcription factor 3	0.013
Dlx1	distal-less homeobox 1	0.013
Psen1	presenilin 1	0.013
Npr3	natriuretic peptide receptor 3	0.013
Efnb1	ephrin B1	0.013
Tead4	TEA domain family member 4	0.012
Notch1	Notch gene homolog 1 (Drosophila)	0.012
Ihh	Indian hedgehog	0.012
Foxd2	forkhead box D2	0.012
Uncx	UNC homeobox	0.012
Nrtn	neurturin	0.012
Eng	endoglin	0.012
Sox3	SRY-box containing gene 3	0.012	Mouse
Cdh5	cadherin 5	0.012
Hoxd3	homeobox D3	0.012
Unc5c	unc-5 homolog C (C. elegans)	0.012
Runx2	runt related transcription factor 2	0.012
Hoxd11	homeobox D11	0.012
Hoxb6	homeobox B6	0.012
Esam	endothelial cell-specific adhesion molecule	0.012
Hoxa13	homeobox A13	0.012
Hoxa4	homeobox A4	0.012
Nr2e1	nuclear receptor subfamily 2, group E, member 1	0.011
Nr2f1	nuclear receptor subfamily 2, group F, member 1	0.011
Fzd2	frizzled homolog 2 (Drosophila)	0.011
Hoxc4	homeobox C4	0.011
Ushbp1	Usher syndrome 1C binding protein 1	0.011
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.011
Rhox6	reproductive homeobox 6	0.011
Nrk	Nik related kinase	0.011
Fstl1	follistatin-like 1	0.011
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.011
Zfp503	zinc finger protein 503	0.011
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.011
Snai1	snail homolog 1 (Drosophila)	0.011
Foxd1	forkhead box D1	0.011
Nkx3-2	NK3 homeobox 2	0.011
Col13a1	collagen, type XIII, alpha 1	0.011
Fzd8	frizzled homolog 8 (Drosophila)	0.011
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.011
Galr2	galanin receptor 2	0.011
Wnt4	wingless-related MMTV integration site 4	0.010
T	brachyury	0.010
Itga3	integrin alpha 3	0.010
Irs3	insulin receptor substrate 3	0.010
Fgf17	fibroblast growth factor 17	0.010
Odz4	odd Oz/ten-m homolog 4 (Drosophila)	0.010
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.010
Zp1	zona pellucida glycoprotein 1	0.010
Adam17	a disintegrin and metallopeptidase domain 17	0.010
Myl7	myosin, light polypeptide 7, regulatory	0.010