Mus musculus

21 known processes

Irgm2

immunity-related GTPase family M member 2

(Aliases: AI481100,GTPI,MGC102455,Iigp2)

Irgm2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to interferon gamma GO:0034341 34 0.989
defense response to protozoan GO:0042832 25 0.980
cellular response to interferon beta GO:0035458 21 0.959
Mouse
response to protozoan GO:0001562 28 0.950
interspecies interaction between organisms GO:0044419 83 0.947
regulation of defense response to virus by host GO:0050691 8 0.945
innate immune response GO:0045087 157 0.904
type i interferon production GO:0032606 29 0.902
positive regulation of interferon alpha production GO:0032727 4 0.873
positive regulation of rig i signaling pathway GO:1900246 1 0.861
defense response to bacterium GO:0042742 119 0.858
symbiosis encompassing mutualism through parasitism GO:0044403 83 0.854
regulation of interferon alpha production GO:0032647 5 0.851
cellular response to interferon gamma GO:0071346 25 0.842
rig i signaling pathway GO:0039529 4 0.824
negative regulation of defense response to virus by host GO:0050689 1 0.810
defense response to virus GO:0051607 68 0.784
protein modification by small protein conjugation or removal GO:0070647 207 0.768
regulation of defense response GO:0031347 233 0.718
cellular response to molecule of bacterial origin GO:0071219 83 0.714
negative regulation of viral process GO:0048525 23 0.698
negative regulation of interferon alpha production GO:0032687 1 0.687
adhesion of symbiont to host GO:0044406 8 0.682
viral life cycle GO:0019058 36 0.675
positive regulation of type i interferon mediated signaling pathway GO:0060340 4 0.668
cellular response to type i interferon GO:0071357 10 0.642
response to interferon beta GO:0035456 22 0.639
Mouse
cd8 positive alpha beta t cell proliferation GO:0035740 1 0.620
regulation of type i interferon production GO:0032479 22 0.612
regulation of myd88 independent toll like receptor signaling pathway GO:0034127 1 0.602
nucleotide metabolic process GO:0009117 332 0.594
Mouse
regulation of cytokine production GO:0001817 266 0.585
negative regulation of interferon beta production GO:0032688 3 0.579
activation of innate immune response GO:0002218 56 0.550
intracellular protein transport GO:0006886 204 0.509
purine ribonucleotide catabolic process GO:0009154 208 0.504
Mouse
cytokine production GO:0001816 319 0.502
nucleoside triphosphate metabolic process GO:0009141 230 0.491
Mouse
protein ubiquitination GO:0016567 171 0.488
autophagy GO:0006914 45 0.466
Mouse
regulation of type i interferon mediated signaling pathway GO:0060338 7 0.464
negative regulation of cell proliferation GO:0008285 296 0.463
positive regulation of cell killing GO:0031343 33 0.458
regulation of viral entry into host cell GO:0046596 12 0.456
regulation of rig i signaling pathway GO:0039535 2 0.452
purine containing compound catabolic process GO:0072523 213 0.410
Mouse
innate immune response activating signal transduction GO:0002758 50 0.400
regulation of response to biotic stimulus GO:0002831 38 0.399
regulation of myd88 dependent toll like receptor signaling pathway GO:0034124 2 0.392
regulation of viral genome replication GO:0045069 13 0.390
ribonucleoside catabolic process GO:0042454 206 0.389
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.381
Mouse
regulation of nlrp3 inflammasome complex assembly GO:1900225 4 0.379
pattern recognition receptor signaling pathway GO:0002221 47 0.363
positive regulation of type i interferon production GO:0032481 14 0.363
cd4 positive alpha beta t cell lineage commitment GO:0043373 6 0.357
negative regulation of protein phosphorylation GO:0001933 126 0.352
purine nucleoside metabolic process GO:0042278 241 0.347
Mouse
glycosyl compound catabolic process GO:1901658 206 0.341
Mouse
cellular response to lipid GO:0071396 145 0.339
purine nucleoside triphosphate catabolic process GO:0009146 203 0.336
Mouse
response to type i interferon GO:0034340 12 0.331
protein modification by small protein conjugation GO:0032446 187 0.318
glycosyl compound metabolic process GO:1901657 246 0.315
Mouse
nucleobase containing small molecule metabolic process GO:0055086 352 0.309
Mouse
nucleoside metabolic process GO:0009116 246 0.306
Mouse
t helper 1 cell lineage commitment GO:0002296 2 0.295
organophosphate catabolic process GO:0046434 232 0.294
Mouse
nucleotide catabolic process GO:0009166 217 0.294
Mouse
purine nucleoside triphosphate metabolic process GO:0009144 226 0.290
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 199 0.285
Mouse
regulation of autophagy GO:0010506 30 0.284
Mouse
nucleoside triphosphate catabolic process GO:0009143 205 0.283
Mouse
ribonucleoside triphosphate metabolic process GO:0009199 220 0.271
Mouse
defense response to gram negative bacterium GO:0050829 28 0.269
Mouse
positive regulation of viral genome replication GO:0045070 2 0.268
gtp catabolic process GO:0006184 143 0.267
Mouse
regulation of intracellular transport GO:0032386 159 0.266
cellular response to cytokine stimulus GO:0071345 189 0.264
Mouse
regulation of defense response to virus GO:0050688 18 0.262
gtp metabolic process GO:0046039 144 0.250
Mouse
regulation of natural killer cell mediated cytotoxicity GO:0042269 19 0.247
guanosine containing compound catabolic process GO:1901069 144 0.243
Mouse
ribonucleoside metabolic process GO:0009119 245 0.241
Mouse
t helper 17 cell lineage commitment GO:0072540 4 0.239
response to dsrna GO:0043331 30 0.238
nucleoside phosphate catabolic process GO:1901292 222 0.233
Mouse
movement in environment of other organism involved in symbiotic interaction GO:0052192 15 0.231
negative regulation of cellular protein metabolic process GO:0032269 247 0.227
cellular nitrogen compound catabolic process GO:0044270 280 0.224
Mouse
organonitrogen compound catabolic process GO:1901565 264 0.220
Mouse
positive regulation of defense response GO:0031349 124 0.220
regulation of cd8 positive alpha beta t cell activation GO:2001185 3 0.214
ribose phosphate metabolic process GO:0019693 291 0.213
Mouse
carbohydrate derivative catabolic process GO:1901136 231 0.208
Mouse
mda 5 signaling pathway GO:0039530 1 0.204
viral process GO:0016032 41 0.201
cellular response to interferon alpha GO:0035457 4 0.199
cellular response to lipopolysaccharide GO:0071222 77 0.198
defense response to gram positive bacterium GO:0050830 50 0.198
regulation of toll like receptor signaling pathway GO:0034121 20 0.198
purine ribonucleoside metabolic process GO:0046128 241 0.196
Mouse
regulation of innate immune response GO:0045088 91 0.195
defense response to other organism GO:0098542 197 0.192
purine nucleoside catabolic process GO:0006152 205 0.189
Mouse
aromatic compound catabolic process GO:0019439 286 0.188
Mouse
regulation of protein ubiquitination GO:0031396 52 0.186
ribonucleotide metabolic process GO:0009259 291 0.185
Mouse
nucleoside catabolic process GO:0009164 206 0.183
Mouse
interaction with host GO:0051701 22 0.183
response to lipopolysaccharide GO:0032496 128 0.182
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.171
positive regulation of innate immune response GO:0045089 80 0.170
purine ribonucleoside catabolic process GO:0046130 205 0.168
Mouse
guanosine containing compound metabolic process GO:1901068 144 0.165
Mouse
negative regulation of nlrp3 inflammasome complex assembly GO:1900226 2 0.163
cytoplasmic pattern recognition receptor signaling pathway in response to virus GO:0039528 4 0.160
regulation of defense response to bacterium GO:1900424 3 0.159
citrate metabolic process GO:0006101 3 0.159
negative regulation of defense response GO:0031348 77 0.157
negative regulation of phosphate metabolic process GO:0045936 184 0.157
organic cyclic compound catabolic process GO:1901361 295 0.157
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.152
Mouse
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 52 0.150
negative regulation of protein modification process GO:0031400 163 0.149
regulation of viral release from host cell GO:1902186 6 0.149
movement in host environment GO:0052126 15 0.144
histone modification GO:0016570 159 0.142
syncytium formation by plasma membrane fusion GO:0000768 42 0.134
regulation of protein transport GO:0051223 163 0.134
positive regulation of cytokine production GO:0001819 174 0.132
negative regulation of cytokine production GO:0001818 84 0.132
negative regulation of t cell differentiation GO:0045581 23 0.131
negative regulation of protein metabolic process GO:0051248 282 0.130
negative regulation of cytoplasmic transport GO:1903650 29 0.129
protein import GO:0017038 101 0.128
positive regulation of mirna metabolic process GO:2000630 1 0.126
purine nucleotide metabolic process GO:0006163 302 0.126
Mouse
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.124
negative regulation of immune system process GO:0002683 209 0.123
negative regulation of intracellular protein transport GO:0090317 27 0.121
regulation of multi organism process GO:0043900 111 0.121
myeloid leukocyte differentiation GO:0002573 119 0.120
immune effector process GO:0002252 321 0.119
response to molecule of bacterial origin GO:0002237 143 0.114
toll like receptor signaling pathway GO:0002224 38 0.113
negative regulation of multi organism process GO:0043901 68 0.113
ribonucleotide catabolic process GO:0009261 208 0.112
Mouse
entry into cell of other organism involved in symbiotic interaction GO:0051806 15 0.112
regulation of cd8 positive alpha beta t cell proliferation GO:2000564 1 0.107
purine containing compound metabolic process GO:0072521 311 0.106
Mouse
positive regulation of viral entry into host cell GO:0046598 3 0.104
purine ribonucleotide metabolic process GO:0009150 290 0.103
Mouse
regulation of cellular catabolic process GO:0031329 242 0.101
Mouse
negative regulation of viral release from host cell GO:1902187 6 0.096
immune response regulating signaling pathway GO:0002764 125 0.095
leukocyte mediated immunity GO:0002443 174 0.094
nucleocytoplasmic transport GO:0006913 139 0.092
cd4 positive alpha beta t cell activation GO:0035710 45 0.090
immune response activating signal transduction GO:0002757 116 0.088
negative regulation of defense response to virus GO:0050687 6 0.087
response to organic cyclic compound GO:0014070 198 0.085
cell fate commitment GO:0045165 210 0.084
positive regulation of immune effector process GO:0002699 107 0.084
regulation of interferon beta biosynthetic process GO:0045357 4 0.083
t cell lineage commitment GO:0002360 13 0.083
isg15 protein conjugation GO:0032020 4 0.080
natural killer cell proliferation GO:0001787 3 0.079
viral gene expression GO:0019080 3 0.078
allantoin metabolic process GO:0000255 3 0.077
regulation of intracellular protein transport GO:0033157 82 0.077
t cell proliferation GO:0042098 120 0.077
type i interferon signaling pathway GO:0060337 10 0.075
regulation of interferon beta production GO:0032648 13 0.075
regulation of leukocyte differentiation GO:1902105 159 0.074
histone h4 acetylation GO:0043967 10 0.072
entry into host GO:0044409 15 0.071
cytoplasmic transport GO:0016482 234 0.071
protein localization to nucleus GO:0034504 121 0.071
entry into other organism involved in symbiotic interaction GO:0051828 15 0.070
negative regulation of intracellular transport GO:0032387 38 0.069
covalent chromatin modification GO:0016569 163 0.068
lipopolysaccharide mediated signaling pathway GO:0031663 25 0.067
regulation of syncytium formation by plasma membrane fusion GO:0060142 23 0.066
regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039531 2 0.066
myeloid cell homeostasis GO:0002262 114 0.065
valine metabolic process GO:0006573 4 0.064
cd8 positive alpha beta t cell differentiation GO:0043374 9 0.064
macromolecule catabolic process GO:0009057 281 0.063
negative regulation of viral entry into host cell GO:0046597 10 0.063
regulation of mast cell differentiation GO:0060375 3 0.061
natural killer cell activation GO:0030101 44 0.061
t cell activation GO:0042110 289 0.059
skin development GO:0043588 220 0.059
schwann cell proliferation GO:0014010 2 0.059
regulation of cytokine biosynthetic process GO:0042035 59 0.058
positive regulation of natural killer cell mediated immunity GO:0002717 16 0.057
cellular amino acid metabolic process GO:0006520 103 0.057
regulation of cell cycle GO:0051726 281 0.057
positive regulation of peptidase activity GO:0010952 49 0.057
cellular macromolecule catabolic process GO:0044265 206 0.057
regulation of reactive oxygen species metabolic process GO:2000377 40 0.056
creatinine metabolic process GO:0046449 3 0.056
regulation of macrophage fusion GO:0034239 3 0.056
regulation of protein targeting GO:1903533 61 0.055
negative regulation of nucleocytoplasmic transport GO:0046823 23 0.055
negative regulation of phosphorylation GO:0042326 166 0.055
interferon beta production GO:0032608 16 0.055
taurine metabolic process GO:0019530 4 0.054
negative regulation of cell motility GO:2000146 61 0.054
purine nucleotide catabolic process GO:0006195 211 0.054
Mouse
myeloid cell differentiation GO:0030099 233 0.054
interferon alpha production GO:0032607 7 0.052
nlrp3 inflammasome complex assembly GO:0044546 5 0.052
positive regulation of response to cytokine stimulus GO:0060760 11 0.052
negative regulation of toll like receptor signaling pathway GO:0034122 14 0.052
production of small rna involved in gene silencing by rna GO:0070918 6 0.051
interferon beta biosynthetic process GO:0045350 4 0.051
leukocyte mediated cytotoxicity GO:0001909 62 0.050
positive regulation of adaptive immune response GO:0002821 61 0.050
myd88 independent toll like receptor signaling pathway GO:0002756 3 0.049
cytokine mediated signaling pathway GO:0019221 115 0.049
response to phenylpropanoid GO:0080184 22 0.048
stem cell differentiation GO:0048863 268 0.048
negative regulation of phosphorus metabolic process GO:0010563 184 0.048
cellular response to dna damage stimulus GO:0006974 207 0.048
positive regulation of mast cell differentiation GO:0060376 1 0.048
response to organonitrogen compound GO:0010243 246 0.048
t helper cell differentiation GO:0042093 28 0.048
negative regulation of protein transport GO:0051224 46 0.047
negative regulation of macrophage fusion GO:0034240 1 0.047
negative regulation of immune effector process GO:0002698 55 0.047
regulation of lymphocyte activation GO:0051249 240 0.046
dna repair GO:0006281 107 0.046
negative regulation of nervous system development GO:0051961 156 0.045
cell killing GO:0001906 67 0.045
negative regulation of rig i signaling pathway GO:0039536 2 0.045
adaptive immune response GO:0002250 155 0.045
cellular lactam metabolic process GO:0072338 3 0.045
negative regulation of protein import into nucleus GO:0042308 21 0.044
pre mirna processing GO:0031054 3 0.044
histone acetylation GO:0016573 41 0.044
necroptotic signaling pathway GO:0097527 3 0.044
cellular ketone metabolic process GO:0042180 84 0.043
protein oligomerization GO:0051259 67 0.043
regulation of necroptotic process GO:0060544 10 0.043
lymphocyte mediated immunity GO:0002449 139 0.043
syncytium formation GO:0006949 43 0.043
regulation of type 2 immune response GO:0002828 18 0.040
regulation of cytoplasmic transport GO:1903649 112 0.040
dna metabolic process GO:0006259 303 0.040
positive regulation of mapk cascade GO:0043410 170 0.040
cd4 positive or cd8 positive alpha beta t cell lineage commitment GO:0043369 8 0.040
regulation of interferon gamma production GO:0032649 57 0.040
reactive oxygen species metabolic process GO:0072593 84 0.039
positive regulation of t cell mediated cytotoxicity GO:0001916 15 0.039
negative regulation of cell development GO:0010721 169 0.039
regulation of protein import into nucleus GO:0042306 52 0.038
negative regulation of protein modification by small protein conjugation or removal GO:1903321 20 0.038
regulation of cell killing GO:0031341 40 0.038
negative regulation of protein ubiquitination GO:0031397 19 0.038
nuclear transport GO:0051169 139 0.038
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 61 0.038
negative regulation of cellular component organization GO:0051129 194 0.037
regulation of protein complex assembly GO:0043254 83 0.037
negative regulation of interferon beta biosynthetic process GO:0045358 1 0.036
chromatin organization GO:0006325 206 0.036
activation of immune response GO:0002253 138 0.035
iron ion homeostasis GO:0055072 36 0.035
creatine metabolic process GO:0006600 4 0.034
negative regulation of viral transcription GO:0032897 3 0.034
b cell mediated immunity GO:0019724 71 0.034
erythrocyte differentiation GO:0030218 88 0.034
negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway GO:0039532 2 0.034
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.034
protein alkylation GO:0008213 81 0.033
protein methylation GO:0006479 81 0.033
positive regulation of protein complex assembly GO:0031334 45 0.033
regulation of t cell activation GO:0050863 170 0.033
alpha beta t cell activation involved in immune response GO:0002287 31 0.032
gland development GO:0048732 330 0.032
protein import into nucleus GO:0006606 95 0.032
regulation of nucleocytoplasmic transport GO:0046822 73 0.032
negative regulation of t cell activation GO:0050868 65 0.032
regulation of b cell differentiation GO:0045577 23 0.032
regulation of neutrophil mediated killing of gram negative bacterium GO:0070951 1 0.032
leukocyte proliferation GO:0070661 172 0.032
t cell differentiation GO:0030217 174 0.032
entry into host cell GO:0030260 15 0.031
homeostasis of number of cells GO:0048872 210 0.030
response to granulocyte macrophage colony stimulating factor GO:0097012 3 0.030
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 16 0.030
peptidyl lysine methylation GO:0018022 29 0.030
natural killer cell mediated cytotoxicity GO:0042267 29 0.030
regulation of adaptive immune response GO:0002819 90 0.030
response to interferon alpha GO:0035455 7 0.030
Mouse
positive regulation of proteolysis GO:0045862 85 0.029
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 36 0.029
cell type specific apoptotic process GO:0097285 268 0.029
positive regulation of myelination GO:0031643 5 0.029
olfactory bulb development GO:0021772 30 0.028
t helper 2 cell cytokine production GO:0035745 4 0.028
epidermis development GO:0008544 187 0.028
regulation of cellular component biogenesis GO:0044087 181 0.028
negative regulation of angiogenesis GO:0016525 25 0.028
single organism nuclear import GO:1902593 95 0.028
cellular response to biotic stimulus GO:0071216 92 0.028
negative regulation of innate immune response GO:0045824 17 0.028
regulation of epithelial cell proliferation GO:0050678 141 0.027
negative regulation of syncytium formation by plasma membrane fusion GO:0034242 5 0.027
macromolecule methylation GO:0043414 120 0.027
interferon gamma mediated signaling pathway GO:0060333 5 0.027
positive regulation of myeloid cell differentiation GO:0045639 43 0.027
viral genome replication GO:0019079 17 0.027
protein catabolic process GO:0030163 221 0.026
production of molecular mediator of immune response GO:0002440 103 0.026
immunoglobulin mediated immune response GO:0016064 69 0.026
keratinocyte differentiation GO:0030216 48 0.026
regulation of cell activation GO:0050865 289 0.026
regulation of lymphocyte proliferation GO:0050670 117 0.026
inflammatory response GO:0006954 244 0.026
digestive system development GO:0055123 200 0.026
interleukin 4 mediated signaling pathway GO:0035771 2 0.025
spleen development GO:0048536 39 0.025
regulation of viral transcription GO:0046782 3 0.025
germ cell development GO:0007281 185 0.025
organism emergence from protective structure GO:0071684 4 0.025
lipid homeostasis GO:0055088 63 0.025
development of primary female sexual characteristics GO:0046545 73 0.025
hair follicle cell proliferation GO:0071335 3 0.024
respiratory system development GO:0060541 190 0.024
establishment of protein localization to organelle GO:0072594 118 0.024
protein localization to organelle GO:0033365 185 0.024
regulation of peptidase activity GO:0052547 96 0.024
reactive nitrogen species metabolic process GO:2001057 0 0.024
mast cell apoptotic process GO:0033024 5 0.023
modification dependent protein catabolic process GO:0019941 133 0.023
negative regulation of lymphocyte differentiation GO:0045620 32 0.023
isotype switching GO:0045190 36 0.023
regulation of protein localization GO:0032880 231 0.023
heterocycle catabolic process GO:0046700 280 0.023
Mouse
negative regulation of molecular function GO:0044092 258 0.023
pyroptosis GO:0070269 8 0.023
response to interleukin 15 GO:0070672 3 0.023
regulation of leukocyte mediated cytotoxicity GO:0001910 38 0.022
leukocyte activation involved in immune response GO:0002366 126 0.022
hatching GO:0035188 4 0.022
organophosphate biosynthetic process GO:0090407 122 0.022
regulation of binding GO:0051098 111 0.022
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.022
cellular response to granulocyte macrophage colony stimulating factor stimulus GO:0097011 3 0.022
negative regulation of leukocyte differentiation GO:1902106 51 0.022
regulation of protein localization to nucleus GO:1900180 60 0.022
rhythmic process GO:0048511 174 0.022
response to stilbenoid GO:0035634 22 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.022
regulation of dna binding GO:0051101 39 0.021
alpha beta t cell lineage commitment GO:0002363 7 0.021
cell adhesion GO:0007155 329 0.021
stem cell development GO:0048864 219 0.021
positive regulation of interferon beta production GO:0032728 8 0.021
ossification GO:0001503 216 0.021
viral transcription GO:0019083 3 0.021
t helper 17 cell differentiation GO:0072539 7 0.021
t helper cell lineage commitment GO:0002295 6 0.020
regulation of homeostatic process GO:0032844 182 0.020
negative regulation of growth of symbiont in host GO:0044130 19 0.020
cellular amine metabolic process GO:0044106 44 0.020
regulation of actin nucleation GO:0051125 4 0.020
negative regulation of natural killer cell mediated immunity GO:0002716 5 0.020
progesterone metabolic process GO:0042448 4 0.020
protein targeting GO:0006605 143 0.020
leukocyte apoptotic process GO:0071887 71 0.020
regulation of establishment of protein localization GO:0070201 181 0.020
regulation of t cell mediated immunity GO:0002709 34 0.020
regulation of leukocyte apoptotic process GO:2000106 56 0.020
cellular modified amino acid metabolic process GO:0006575 63 0.019
transcription initiation from rna polymerase ii promoter GO:0006367 8 0.019
cellular lipid metabolic process GO:0044255 323 0.019
positive regulation of interleukin 1 alpha secretion GO:0050717 3 0.019
epithelial cell proliferation GO:0050673 174 0.019
regulation of odontogenesis of dentin containing tooth GO:0042487 11 0.019
generation of precursor metabolites and energy GO:0006091 103 0.019
antimicrobial peptide biosynthetic process GO:0002777 2 0.019
muscle tissue development GO:0060537 308 0.019
limb morphogenesis GO:0035108 149 0.019
regulation of mast cell proliferation GO:0070666 4 0.019
eye photoreceptor cell differentiation GO:0001754 41 0.019
organelle assembly GO:0070925 177 0.019
double strand break repair GO:0006302 48 0.019
natural killer cell mediated immunity GO:0002228 29 0.018
nucleoside monophosphate metabolic process GO:0009123 85 0.018
regulation of neuron migration GO:2001222 22 0.018
internal protein amino acid acetylation GO:0006475 42 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.018
Mouse
positive regulation of actin nucleation GO:0051127 3 0.018
gliogenesis GO:0042063 141 0.018
purine nucleoside monophosphate metabolic process GO:0009126 81 0.018
negative regulation of viral genome replication GO:0045071 10 0.018
positive regulation of cytokine biosynthetic process GO:0042108 40 0.018
carbohydrate metabolic process GO:0005975 230 0.018
negative regulation of cell activation GO:0050866 111 0.018
chromatin modification GO:0016568 187 0.018
mast cell proliferation GO:0070662 4 0.018
regulation of myeloid cell differentiation GO:0045637 96 0.018
regulation of t cell proliferation GO:0042129 92 0.018
notch signaling pathway GO:0007219 71 0.018
i kappab kinase nf kappab signaling GO:0007249 85 0.018
activation of cysteine type endopeptidase activity GO:0097202 27 0.018
programmed necrotic cell death GO:0097300 28 0.017
embryonic appendage morphogenesis GO:0035113 126 0.017
regulation of response to wounding GO:1903034 189 0.017
positive t cell selection GO:0043368 23 0.017
regulation of dna templated transcription initiation GO:2000142 7 0.017
t cell differentiation in thymus GO:0033077 77 0.017
regulation of endopeptidase activity GO:0052548 89 0.017
alpha beta t cell differentiation involved in immune response GO:0002293 30 0.017
alpha amino acid metabolic process GO:1901605 59 0.017
positive regulation of protein catabolic process GO:0045732 60 0.017
cellular response to exogenous dsrna GO:0071360 5 0.017
negative regulation of intracellular signal transduction GO:1902532 167 0.017
cellular protein catabolic process GO:0044257 155 0.017
urogenital system development GO:0001655 261 0.017
angiogenesis GO:0001525 201 0.017
pyrimidine containing compound catabolic process GO:0072529 3 0.017
maintenance of location GO:0051235 89 0.017
positive regulation of lymphocyte mediated immunity GO:0002708 62 0.017
regulation of schwann cell proliferation GO:0010624 2 0.016
positive regulation of viral process GO:0048524 5 0.016
photoreceptor cell differentiation GO:0046530 52 0.016
positive regulation of binding GO:0051099 49 0.016
mammary gland epithelial cell differentiation GO:0060644 13 0.016
regulation of interleukin 1 alpha production GO:0032650 4 0.016
response to unfolded protein GO:0006986 21 0.016
regulation of proteolysis GO:0030162 164 0.016
apoptotic signaling pathway GO:0097190 306 0.016
extrinsic apoptotic signaling pathway GO:0097191 126 0.016
myeloid dendritic cell activation GO:0001773 25 0.016
multicellular organism growth GO:0035264 161 0.016
epithelial tube morphogenesis GO:0060562 303 0.016
cytokine metabolic process GO:0042107 71 0.016
positive regulation of cellular component biogenesis GO:0044089 94 0.016
peripheral nervous system development GO:0007422 53 0.016
regulation of membrane potential GO:0042391 192 0.016
histone h3 acetylation GO:0043966 14 0.016
regulation of body fluid levels GO:0050878 162 0.016
pyridine nucleotide biosynthetic process GO:0019363 4 0.016
connective tissue development GO:0061448 179 0.016
positive regulation of cell death GO:0010942 224 0.016
schwann cell differentiation GO:0014037 26 0.015
mammary gland epithelium development GO:0061180 65 0.015
positive regulation of programmed cell death GO:0043068 218 0.015
positive regulation of leukocyte differentiation GO:1902107 86 0.015
regulation of lymphocyte mediated immunity GO:0002706 84 0.015
cellular carbohydrate metabolic process GO:0044262 119 0.015
regulation of lipid metabolic process GO:0019216 118 0.015
negative regulation of glycolytic process GO:0045820 4 0.015
central nervous system neuron differentiation GO:0021953 162 0.015
regulation of glycolytic process GO:0006110 10 0.015
olfactory bulb interneuron differentiation GO:0021889 12 0.015
cellular response to dsrna GO:0071359 12 0.015
actin cytoskeleton organization GO:0030036 220 0.015
regulation of hormone levels GO:0010817 211 0.015
negative regulation of regulatory t cell differentiation GO:0045590 2 0.015
myd88 dependent toll like receptor signaling pathway GO:0002755 7 0.015
microtubule based process GO:0007017 236 0.015
alpha beta t cell differentiation GO:0046632 69 0.015
peptidyl lysine acetylation GO:0018394 45 0.015
peptidyl lysine modification GO:0018205 77 0.015
lymphocyte differentiation GO:0030098 242 0.014
isoleucine metabolic process GO:0006549 4 0.014
cellular response to organonitrogen compound GO:0071417 145 0.014
regulation of cell migration GO:0030334 219 0.014
keratinocyte proliferation GO:0043616 21 0.014
limb development GO:0060173 166 0.014
blood vessel morphogenesis GO:0048514 285 0.014
leukocyte differentiation GO:0002521 342 0.014
peptidyl amino acid modification GO:0018193 336 0.014
negative regulation of protein binding GO:0032091 17 0.014
male sex differentiation GO:0046661 109 0.014
regulation of organelle organization GO:0033043 289 0.014
fatty acid metabolic process GO:0006631 121 0.014
multicellular organismal signaling GO:0035637 91 0.014
response to endoplasmic reticulum stress GO:0034976 53 0.014
regulation of gliogenesis GO:0014013 50 0.014
cell activation involved in immune response GO:0002263 126 0.014
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 36 0.014
positive regulation of leukocyte mediated cytotoxicity GO:0001912 31 0.014
negative regulation of epithelial cell proliferation GO:0050680 64 0.014
er nucleus signaling pathway GO:0006984 27 0.013
ubiquitin dependent protein catabolic process GO:0006511 129 0.013
b cell activation involved in immune response GO:0002312 50 0.013
purine nucleoside monophosphate catabolic process GO:0009128 58 0.013
protein acylation GO:0043543 64 0.013
positive regulation of dna binding GO:0043388 14 0.013
jak stat cascade involved in growth hormone signaling pathway GO:0060397 4 0.013

Irgm2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.018