IMP
Process View
pyroptosis
A caspase-1-dependent cell death subroutine that is associated with the generation of pyrogenic mediators such as IL-1beta and IL-18.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "pyroptosis"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Gbp5 | guanylate binding protein 5 | 0.998 | ||
| Pycard | PYD and CARD domain containing | 0.994 | ||
| Aim2 | absent in melanoma 2 | 0.988 | ||
| Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.987 | ||
| Casp1 | caspase 1 | 0.975 | ||
| Tlr4 | toll-like receptor 4 | 0.894 | ||
| Mndal | myeloid nuclear differentiation antigen like | 0.640 | ||
| Gbp3 | guanylate binding protein 3 | 0.559 | ||
| Il18 | interleukin 18 | 0.356 | ||
| Gbp7 | guanylate binding protein 7 | 0.316 | ||
| Nmi | N-myc (and STAT) interactor | 0.315 | ||
| Gbp2 | guanylate binding protein 2 | 0.262 | ||
| Il1b | interleukin 1 beta | 0.255 | ||
| Ifih1 | interferon induced with helicase C domain 1 | 0.126 | ||
| Ly96 | lymphocyte antigen 96 | 0.117 | ||
| Irgm1 | immunity-related GTPase family M member 1 | 0.102 | ||
| Naip2 | NLR family, apoptosis inhibitory protein 2 | 0.100 | ||
| Hccs | holocytochrome c synthetase | 0.083 | ||
| Trim30a | tripartite motif-containing 30A | 0.077 | ||
| Naip5 | NLR family, apoptosis inhibitory protein 5 | 0.060 | ||
| Nlrp3 | NLR family, pyrin domain containing 3 | 0.060 | ||
| Trim30d | tripartite motif-containing 30D | 0.060 | ||
| Apobec1 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 | 0.056 | ||
| Stat1 | signal transducer and activator of transcription 1 | 0.051 | ||
| Myd88 | myeloid differentiation primary response gene 88 | 0.049 | ||
| Iigp1 | interferon inducible GTPase 1 | 0.048 | ||
| Trim21 | tripartite motif-containing 21 | 0.038 | ||
| Tnfsf10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.032 | ||
| Fgl2 | fibrinogen-like protein 2 | 0.029 | ||
| AW112010 | expressed sequence AW112010 | 0.029 | ||
| Casp7 | caspase 7 | 0.028 | Mouse | |
| Ifi47 | interferon gamma inducible protein 47 | 0.027 | ||
| Ms4a6b | membrane-spanning 4-domains, subfamily A, member 6B | 0.024 | ||
| Ifi203 | interferon activated gene 203 | 0.023 | Mouse | |
| Irgm2 | immunity-related GTPase family M member 2 | 0.023 | ||
| Hif1a | hypoxia inducible factor 1, alpha subunit | 0.022 | ||
| Tlr1 | toll-like receptor 1 | 0.021 | ||
| Serpinb9 | serine (or cysteine) peptidase inhibitor, clade B, member 9 | 0.021 | ||
| Parp14 | poly (ADP-ribose) polymerase family, member 14 | 0.019 | ||
| H2-M3 | histocompatibility 2, M region locus 3 | 0.018 | ||
| Erap1 | endoplasmic reticulum aminopeptidase 1 | 0.018 | ||
| Eif2ak2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.018 | ||
| Nat2 | N-acetyltransferase 2 (arylamine N-acetyltransferase) | 0.016 | ||
| Ifit2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.016 | ||
| Birc3 | baculoviral IAP repeat-containing 3 | 0.016 | Mouse | |
| Casp8 | caspase 8 | 0.015 | Mouse | |
| Ifit1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.014 | ||
| Tlr3 | toll-like receptor 3 | 0.013 | ||
| Mnda | myeloid cell nuclear differentiation antigen | 0.013 | ||
| Mx1 | myxovirus (influenza virus) resistance 1 | 0.012 | ||
| Ripk3 | receptor-interacting serine-threonine kinase 3 | 0.012 | ||
| Parp9 | poly (ADP-ribose) polymerase family, member 9 | 0.012 | ||
| Casp3 | caspase 3 | 0.012 | Mouse | |
| Psmb9 | proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) | 0.011 | ||
| Ctsc | cathepsin C | 0.011 | ||
| D14Ertd668e | DNA segment, Chr 14, ERATO Doi 668, expressed | 0.011 |