Mus musculus

104 known processes

Mertk

c-mer proto-oncogene tyrosine kinase

(Aliases: Nyk,Eyk,Mer)

Mertk biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
glycerolipid metabolic process GO:0046486 122 0.597
hemostasis GO:0007599 78 0.594
coagulation GO:0050817 78 0.560
peptidyl tyrosine phosphorylation GO:0018108 143 0.513
Mouse
gland development GO:0048732 330 0.498
Mouse
regulation of body fluid levels GO:0050878 162 0.493
hepatocyte growth factor receptor signaling pathway GO:0048012 3 0.492
Mouse
negative regulation of neuron projection development GO:0010977 50 0.459
Mouse
inflammatory response GO:0006954 244 0.456
Mouse
blood coagulation GO:0007596 76 0.439
positive regulation of transferase activity GO:0051347 167 0.411
Mouse
cell adhesion GO:0007155 329 0.385
regulation of transferase activity GO:0051338 263 0.374
Mouse
cellular lipid metabolic process GO:0044255 323 0.371
positive regulation of protein modification process GO:0031401 299 0.368
Mouse
positive regulation of kinase activity GO:0033674 155 0.343
Mouse
negative regulation of axon guidance GO:1902668 8 0.331
Mouse
positive regulation of protein phosphorylation GO:0001934 242 0.331
Mouse
cellular homeostasis GO:0019725 240 0.328
Mouse
regulation of response to wounding GO:1903034 189 0.322
Mouse
glucose transport GO:0015758 56 0.318
Mouse
cell substrate adhesion GO:0031589 130 0.317
tissue remodeling GO:0048771 102 0.304
Mouse
negative chemotaxis GO:0050919 14 0.299
Mouse
regulation of cellular component size GO:0032535 121 0.299
Mouse
regulation of defense response GO:0031347 233 0.283
Mouse
glucose homeostasis GO:0042593 128 0.282
Mouse
endocytosis GO:0006897 168 0.280
protein autophosphorylation GO:0046777 61 0.276
Mouse
single organism cell adhesion GO:0098602 156 0.268
negative regulation of growth GO:0045926 99 0.265
Mouse
skeletal system development GO:0001501 356 0.257
Mouse
regulation of protein kinase activity GO:0045859 232 0.254
Mouse
negative regulation of cellular component organization GO:0051129 194 0.252
Mouse
cytokine production GO:0001816 319 0.249
Mouse
regulation of anatomical structure size GO:0090066 178 0.248
Mouse
positive regulation of protein kinase b signaling GO:0051897 32 0.248
Mouse
regulation of cell migration GO:0030334 219 0.242
phospholipid metabolic process GO:0006644 87 0.239
regulation of mapk cascade GO:0043408 248 0.238
Mouse
transmembrane transport GO:0055085 412 0.233
positive regulation of mapk cascade GO:0043410 170 0.231
Mouse
regulation of kinase activity GO:0043549 249 0.230
Mouse
carbohydrate homeostasis GO:0033500 128 0.227
Mouse
muscle tissue development GO:0060537 308 0.227
Mouse
wnt signaling pathway GO:0016055 188 0.225
Mouse
myeloid cell homeostasis GO:0002262 114 0.224
Mouse
branching involved in salivary gland morphogenesis GO:0060445 26 0.223
Mouse
regulation of cell projection organization GO:0031344 206 0.220
Mouse
organic cyclic compound catabolic process GO:1901361 295 0.219
regulation of cell motility GO:2000145 236 0.216
positive regulation of glucose transport GO:0010828 16 0.215
Mouse
regulation of chemotaxis GO:0050920 53 0.213
Mouse
neuron projection extension GO:1990138 64 0.209
Mouse
angiogenesis GO:0001525 201 0.208
cellular lipid catabolic process GO:0044242 52 0.208
platelet aggregation GO:0070527 20 0.208
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.207
Mouse
regulation of phospholipase a2 activity GO:0032429 3 0.204
semaphorin plexin signaling pathway GO:0071526 21 0.202
Mouse
positive regulation of protein kinase activity GO:0045860 144 0.196
Mouse
anion transport GO:0006820 177 0.195
positive regulation of map kinase activity GO:0043406 84 0.190
Mouse
regulation of membrane potential GO:0042391 192 0.189
Mouse
negative regulation of response to wounding GO:1903035 77 0.189
Mouse
cellular amine metabolic process GO:0044106 44 0.188
mapk cascade GO:0000165 281 0.187
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.187
ion transmembrane transport GO:0034220 361 0.184
activation of immune response GO:0002253 138 0.183
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.181
oxidation reduction process GO:0055114 342 0.177
regulation of protein serine threonine kinase activity GO:0071900 157 0.176
Mouse
negative regulation of cell morphogenesis involved in differentiation GO:0010771 48 0.171
Mouse
glycosyl compound metabolic process GO:1901657 246 0.169
negative regulation of neuron death GO:1901215 98 0.167
Mouse
positive regulation of cellular catabolic process GO:0031331 148 0.165
liver development GO:0001889 66 0.164
Mouse
forebrain development GO:0030900 302 0.163
Mouse
membrane depolarization GO:0051899 64 0.160
Mouse
regulation of map kinase activity GO:0043405 120 0.156
Mouse
intracellular cholesterol transport GO:0032367 3 0.156
anatomical structure homeostasis GO:0060249 145 0.153
Mouse
regulation of secretion by cell GO:1903530 249 0.151
immune response regulating signaling pathway GO:0002764 125 0.151
Mouse
lipid catabolic process GO:0016042 69 0.151
regulation of postsynaptic membrane potential GO:0060078 48 0.150
Mouse
developmental growth involved in morphogenesis GO:0060560 138 0.150
Mouse
carbohydrate transport GO:0008643 62 0.148
Mouse
carboxylic acid transport GO:0046942 100 0.148
negative regulation of cell growth GO:0030308 44 0.147
Mouse
neuron death GO:0070997 154 0.146
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.146
Mouse
regulation of glucose transport GO:0010827 32 0.146
Mouse
skeletal system morphogenesis GO:0048705 203 0.145
Mouse
corpus callosum development GO:0022038 10 0.142
Mouse
small gtpase mediated signal transduction GO:0007264 97 0.141
axonogenesis GO:0007409 274 0.139
Mouse
g protein coupled receptor signaling pathway GO:0007186 243 0.137
skeletal muscle organ development GO:0060538 163 0.137
Mouse
muscle cell migration GO:0014812 19 0.137
Mouse
hepaticobiliary system development GO:0061008 67 0.136
Mouse
purine nucleotide metabolic process GO:0006163 302 0.135
organic hydroxy compound transport GO:0015850 93 0.135
hexose transport GO:0008645 56 0.135
Mouse
negative regulation of cell activation GO:0050866 111 0.134
toll like receptor signaling pathway GO:0002224 38 0.129
Mouse
peptidyl amino acid modification GO:0018193 336 0.128
Mouse
cellular chemical homeostasis GO:0055082 215 0.128
peptidyl tyrosine modification GO:0018212 145 0.127
Mouse
cellular response to cytokine stimulus GO:0071345 189 0.126
positive regulation of cellular amine metabolic process GO:0033240 5 0.126
regulation of neuron apoptotic process GO:0043523 122 0.126
Mouse
regulation of beta amyloid clearance GO:1900221 1 0.126
phagocytosis GO:0006909 66 0.124
organonitrogen compound catabolic process GO:1901565 264 0.123
positive regulation of cell migration GO:0030335 109 0.121
cytokine mediated signaling pathway GO:0019221 115 0.120
cell type specific apoptotic process GO:0097285 268 0.120
Mouse
ribonucleotide metabolic process GO:0009259 291 0.120
lymphocyte differentiation GO:0030098 242 0.120
nucleoside triphosphate metabolic process GO:0009141 230 0.120
aromatic compound catabolic process GO:0019439 286 0.119
forebrain cell migration GO:0021885 58 0.118
Mouse
platelet activation GO:0030168 40 0.117
regulation of inflammatory response GO:0050727 147 0.117
Mouse
nucleoside catabolic process GO:0009164 206 0.117
blood vessel remodeling GO:0001974 33 0.117
Mouse
regulation of dendritic cell apoptotic process GO:2000668 3 0.117
response to extracellular stimulus GO:0009991 127 0.116
Mouse
regulation of cell activation GO:0050865 289 0.116
morphogenesis of a branching epithelium GO:0061138 193 0.115
Mouse
nucleoside phosphate metabolic process GO:0006753 338 0.114
neuron apoptotic process GO:0051402 142 0.114
Mouse
positive regulation of innate immune response GO:0045089 80 0.112
Mouse
regulation of neuron differentiation GO:0045664 281 0.112
Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.111
defense response to bacterium GO:0042742 119 0.111
substrate adhesion dependent cell spreading GO:0034446 30 0.110
response to nutrient levels GO:0031667 109 0.109
negative regulation of innate immune response GO:0045824 17 0.109
Mouse
pattern recognition receptor signaling pathway GO:0002221 47 0.109
Mouse
regulation of cytokine production GO:0001817 266 0.107
Mouse
organic acid transport GO:0015849 101 0.106
protein kinase b signaling GO:0043491 74 0.106
cation transport GO:0006812 399 0.104
striated muscle tissue development GO:0014706 293 0.103
Mouse
regulation of ion transport GO:0043269 215 0.103
regulation of excitatory postsynaptic membrane potential GO:0060079 41 0.102
Mouse
natural killer cell activation GO:0030101 44 0.101
negative regulation of neuron apoptotic process GO:0043524 92 0.100
Mouse
phospholipid catabolic process GO:0009395 5 0.100
camera type eye development GO:0043010 266 0.099
organophosphate biosynthetic process GO:0090407 122 0.099
organophosphate catabolic process GO:0046434 232 0.098
response to lipopolysaccharide GO:0032496 128 0.097
regulation of organelle organization GO:0033043 289 0.096
regulation of secretion GO:0051046 274 0.095
protein localization to nucleus GO:0034504 121 0.095
epithelial cell proliferation GO:0050673 174 0.094
purine ribonucleotide catabolic process GO:0009154 208 0.094
cellular amino acid metabolic process GO:0006520 103 0.094
nitrogen compound transport GO:0071705 271 0.093
ribose phosphate metabolic process GO:0019693 291 0.093
leukocyte differentiation GO:0002521 342 0.093
ribonucleotide catabolic process GO:0009261 208 0.092
positive regulation of defense response GO:0031349 124 0.092
Mouse
regulation of natural killer cell activation GO:0032814 22 0.092
negative regulation of defense response GO:0031348 77 0.091
Mouse
single organismal cell cell adhesion GO:0016337 131 0.091
Mouse
negative regulation of intracellular signal transduction GO:1902532 167 0.091
actin cytoskeleton organization GO:0030036 220 0.090
cellular response to extracellular stimulus GO:0031668 81 0.090
Mouse
heterocycle catabolic process GO:0046700 280 0.089
activation of mapk activity GO:0000187 59 0.089
Mouse
wound healing GO:0042060 157 0.088
organic anion transport GO:0015711 137 0.088
nucleotide metabolic process GO:0009117 332 0.088
regulation of cell adhesion GO:0030155 154 0.088
purine ribonucleotide metabolic process GO:0009150 290 0.087
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.087
glycerolipid biosynthetic process GO:0045017 50 0.087
acylglycerol metabolic process GO:0006639 55 0.086
response to organonitrogen compound GO:0010243 246 0.086
chemotaxis GO:0006935 247 0.086
Mouse
cellular response to biotic stimulus GO:0071216 92 0.086
regulation of tumor necrosis factor production GO:0032680 49 0.085
Mouse
placenta development GO:0001890 140 0.085
Mouse
regulation of system process GO:0044057 200 0.085
salivary gland development GO:0007431 37 0.084
Mouse
ovulation cycle GO:0042698 59 0.083
Mouse
cell growth GO:0016049 130 0.083
Mouse
myoblast proliferation GO:0051450 11 0.082
Mouse
formation of radial glial scaffolds GO:0021943 4 0.082
negative regulation of molecular function GO:0044092 258 0.081
cellular response to lipid GO:0071396 145 0.081
negative regulation of inflammatory response GO:0050728 61 0.081
Mouse
morphogenesis of a branching structure GO:0001763 203 0.079
Mouse
regulation of organ morphogenesis GO:2000027 144 0.078
Mouse
regulation of ras protein signal transduction GO:0046578 114 0.078
regulation of cellular catabolic process GO:0031329 242 0.077
telencephalon development GO:0021537 186 0.077
Mouse
spermatogenesis GO:0007283 284 0.077
positive chemotaxis GO:0050918 18 0.076
Mouse
alcohol metabolic process GO:0006066 116 0.076
regulation of hormone levels GO:0010817 211 0.076
reverse cholesterol transport GO:0043691 6 0.075
nucleobase containing small molecule metabolic process GO:0055086 352 0.075
lipid modification GO:0030258 65 0.074
purine containing compound metabolic process GO:0072521 311 0.073
monosaccharide transport GO:0015749 58 0.073
Mouse
plasma lipoprotein particle organization GO:0071827 11 0.073
organic hydroxy compound metabolic process GO:1901615 203 0.073
sterol transport GO:0015918 38 0.072
regulation of innate immune response GO:0045088 91 0.072
Mouse
negative regulation of cell projection organization GO:0031345 56 0.072
Mouse
regulation of neuron death GO:1901214 134 0.072
Mouse
regulation of hydrolase activity GO:0051336 246 0.071
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.071
nucleotide catabolic process GO:0009166 217 0.070
ras protein signal transduction GO:0007265 77 0.070
leukocyte mediated immunity GO:0002443 174 0.070
positive regulation of membrane protein ectodomain proteolysis GO:0051044 3 0.069
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.068
Mouse
defense response to gram positive bacterium GO:0050830 50 0.068
cellular response to external stimulus GO:0071496 88 0.068
Mouse
sensory perception GO:0007600 245 0.068
ribonucleoside triphosphate catabolic process GO:0009203 199 0.068
g protein coupled receptor internalization GO:0002031 3 0.067
negative regulation of behavior GO:0048521 14 0.067
Mouse
small molecule biosynthetic process GO:0044283 132 0.067
rho protein signal transduction GO:0007266 32 0.067
regulation of axon guidance GO:1902667 13 0.066
Mouse
regulation of branching involved in salivary gland morphogenesis by mesenchymal epithelial signaling GO:0060665 5 0.066
Mouse
ossification GO:0001503 216 0.066
purine nucleoside catabolic process GO:0006152 205 0.065
response to radiation GO:0009314 165 0.065
nucleoside metabolic process GO:0009116 246 0.065
intracellular sterol transport GO:0032366 3 0.064
vacuole organization GO:0007033 38 0.064
regulation of extent of cell growth GO:0061387 52 0.064
Mouse
negative regulation of chemotaxis GO:0050922 11 0.064
Mouse
regulation of cellular component biogenesis GO:0044087 181 0.064
regulation of actin filament based process GO:0032970 99 0.063
regulation of cell size GO:0008361 72 0.062
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 199 0.062
negative regulation of lymphocyte activation GO:0051250 91 0.062
urogenital system development GO:0001655 261 0.062
purine ribonucleoside metabolic process GO:0046128 241 0.061
homeostasis of number of cells GO:0048872 210 0.061
Mouse
regulation of branching involved in salivary gland morphogenesis GO:0060693 11 0.061
Mouse
axon extension involved in axon guidance GO:0048846 14 0.061
Mouse
amino acid transport GO:0006865 61 0.060
dendritic cell apoptotic process GO:0097048 3 0.060
rhythmic process GO:0048511 174 0.060
Mouse
hindbrain development GO:0030902 128 0.060
ribonucleoside metabolic process GO:0009119 245 0.060
response to acid chemical GO:0001101 111 0.060
leukocyte migration GO:0050900 124 0.060
lysosome organization GO:0007040 21 0.059
exocrine system development GO:0035272 45 0.058
Mouse
response to growth factor GO:0070848 198 0.058
glycerophospholipid metabolic process GO:0006650 71 0.058
positive regulation of nervous system development GO:0051962 221 0.058
ribonucleoside triphosphate metabolic process GO:0009199 220 0.057
cellular ketone metabolic process GO:0042180 84 0.057
amine metabolic process GO:0009308 45 0.057
positive regulation of sterol transport GO:0032373 9 0.057
fatty acid metabolic process GO:0006631 121 0.057
steroid metabolic process GO:0008202 119 0.057
amino acid transmembrane transport GO:0003333 37 0.056
regulation of homeostatic process GO:0032844 182 0.056
lipid biosynthetic process GO:0008610 179 0.056
purine ribonucleoside catabolic process GO:0046130 205 0.056
regulation of lymphocyte differentiation GO:0045619 107 0.055
cellular macromolecule catabolic process GO:0044265 206 0.055
lytic vacuole organization GO:0080171 21 0.055
glycosyl compound catabolic process GO:1901658 206 0.055
response to insulin GO:0032868 100 0.055
regulation of actin cytoskeleton organization GO:0032956 84 0.054
negative regulation of neuron differentiation GO:0045665 101 0.054
Mouse
phospholipid transfer to membrane GO:0006649 2 0.054
homotypic cell cell adhesion GO:0034109 28 0.054
Mouse
positive regulation of cell motility GO:2000147 116 0.054
regulation of lymphocyte activation GO:0051249 240 0.053
extrinsic apoptotic signaling pathway GO:0097191 126 0.053
innate immune response GO:0045087 157 0.053
Mouse
positive regulation of ion transport GO:0043270 65 0.053
negative regulation of sterol transport GO:0032372 4 0.053
negative regulation of cytokine production GO:0001818 84 0.052
Mouse
regulation of plasma lipoprotein particle levels GO:0097006 23 0.052
cell chemotaxis GO:0060326 81 0.052
canonical wnt signaling pathway GO:0060070 130 0.052
positive regulation of lymphocyte activation GO:0051251 140 0.052
positive regulation of response to wounding GO:1903036 66 0.052
neuronal action potential GO:0019228 54 0.051
cellular response to lipopolysaccharide GO:0071222 77 0.051
male gamete generation GO:0048232 285 0.051
negative regulation of immune system process GO:0002683 209 0.050
renal system development GO:0072001 225 0.050
carbohydrate derivative catabolic process GO:1901136 231 0.050
actin filament organization GO:0007015 113 0.050
purine nucleotide catabolic process GO:0006195 211 0.050
ear development GO:0043583 200 0.050
negative regulation of cholesterol transport GO:0032375 4 0.050
monocarboxylic acid metabolic process GO:0032787 191 0.049
divalent inorganic cation transport GO:0072511 178 0.049
commissural neuron axon guidance GO:0071679 8 0.049
Mouse
connective tissue development GO:0061448 179 0.049
developmental maturation GO:0021700 193 0.049
maintenance of location GO:0051235 89 0.049
dendritic cell differentiation GO:0097028 26 0.049
tumor necrosis factor superfamily cytokine production GO:0071706 51 0.049
Mouse
regulation of wnt signaling pathway GO:0030111 123 0.049
endothelial cell migration GO:0043542 44 0.048
blood vessel morphogenesis GO:0048514 285 0.048
synaptic transmission GO:0007268 329 0.048
Mouse
ribonucleoside catabolic process GO:0042454 206 0.047
blood circulation GO:0008015 195 0.047
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.047
Mouse
regulation of lipid transport GO:0032368 36 0.047
multicellular organismal signaling GO:0035637 91 0.046
leukocyte apoptotic process GO:0071887 71 0.046
nuclear division GO:0000280 158 0.046
purine containing compound catabolic process GO:0072523 213 0.046
cellular response to molecule of bacterial origin GO:0071219 83 0.046
platelet derived growth factor receptor alpha signaling pathway GO:0035790 3 0.046
purine nucleoside metabolic process GO:0042278 241 0.045
negative regulation of beta amyloid formation GO:1902430 4 0.045
response to amino acid GO:0043200 37 0.045
regulation of cytoskeleton organization GO:0051493 122 0.044
cell maturation GO:0048469 127 0.044
regulation of toll like receptor signaling pathway GO:0034121 20 0.044
Mouse
muscle cell differentiation GO:0042692 261 0.044
Mouse
lipid transport GO:0006869 98 0.044
negative regulation of hydrolase activity GO:0051346 71 0.044
purine nucleoside triphosphate catabolic process GO:0009146 203 0.043
lung development GO:0030324 164 0.043
apoptotic signaling pathway GO:0097190 306 0.043
carbohydrate derivative biosynthetic process GO:1901137 183 0.043
response to oxidative stress GO:0006979 123 0.043
cell activation involved in immune response GO:0002263 126 0.043
sterol metabolic process GO:0016125 58 0.043
negative regulation of cell proliferation GO:0008285 296 0.043
sulfur compound metabolic process GO:0006790 100 0.042
regulation of apoptotic signaling pathway GO:2001233 197 0.042
calcium ion homeostasis GO:0055074 127 0.042
activation of innate immune response GO:0002218 56 0.042
Mouse
l amino acid transport GO:0015807 32 0.042
epithelium migration GO:0090132 63 0.042
regulation of protein kinase b signaling GO:0051896 56 0.042
Mouse
regulation of morphogenesis of a branching structure GO:0060688 53 0.042
Mouse
positive regulation of cholesterol transport GO:0032376 9 0.042
regulation of nucleoside metabolic process GO:0009118 130 0.042
myeloid leukocyte migration GO:0097529 57 0.041
regulation of protein catabolic process GO:0042176 108 0.041
cellular nitrogen compound catabolic process GO:0044270 280 0.041
female sex differentiation GO:0046660 84 0.041
adult behavior GO:0030534 135 0.041
Mouse
anion transmembrane transport GO:0098656 71 0.041
regulation of epithelial cell proliferation GO:0050678 141 0.041
vagina development GO:0060068 11 0.041
protein localization to organelle GO:0033365 185 0.040
regulation of purine nucleotide metabolic process GO:1900542 169 0.040
defense response to other organism GO:0098542 197 0.040
membrane organization GO:0061024 245 0.040
cellular metal ion homeostasis GO:0006875 151 0.040
carbohydrate metabolic process GO:0005975 230 0.040
cellular response to hormone stimulus GO:0032870 150 0.040
cellular ion homeostasis GO:0006873 165 0.040
positive regulation of cell death GO:0010942 224 0.040
cholesterol efflux GO:0033344 24 0.040
cellular response to organonitrogen compound GO:0071417 145 0.039
stem cell differentiation GO:0048863 268 0.039
small molecule catabolic process GO:0044282 71 0.039
skin development GO:0043588 220 0.039
developmental cell growth GO:0048588 84 0.039
Mouse
cytoplasmic transport GO:0016482 234 0.039
organelle fission GO:0048285 170 0.039
nuclear transport GO:0051169 139 0.038
respiratory tube development GO:0030323 167 0.038
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.038
platelet derived growth factor receptor beta signaling pathway GO:0035791 4 0.038
sterol homeostasis GO:0055092 45 0.037
response to peptide GO:1901652 136 0.037
beta amyloid clearance GO:0097242 2 0.037
metanephric glomerular mesangium development GO:0072223 3 0.037
organelle localization GO:0051640 179 0.037
tissue homeostasis GO:0001894 115 0.037
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.037
innate immune response activating signal transduction GO:0002758 50 0.037
Mouse
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.036
negative regulation of phospholipase activity GO:0010519 4 0.036
tissue migration GO:0090130 68 0.036
l alpha amino acid transmembrane transport GO:1902475 23 0.036
macromolecule catabolic process GO:0009057 281 0.036
negative regulation of interferon gamma production GO:0032689 18 0.036
protein lipid complex subunit organization GO:0071825 12 0.036
intracellular protein transport GO:0006886 204 0.036
negative regulation of cellular protein metabolic process GO:0032269 247 0.036
limb morphogenesis GO:0035108 149 0.035
divalent inorganic cation homeostasis GO:0072507 138 0.035
vesicle organization GO:0016050 60 0.035
establishment of organelle localization GO:0051656 122 0.035
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering GO:0097113 3 0.035
metal ion homeostasis GO:0055065 189 0.035
myeloid cell differentiation GO:0030099 233 0.035
regulation of ion transmembrane transport GO:0034765 119 0.035
regulation of neuron projection development GO:0010975 169 0.035
Mouse
negative regulation of phosphorylation GO:0042326 166 0.034
positive regulation of cytokine production GO:0001819 174 0.034
positive regulation of cell activation GO:0050867 158 0.034
negative regulation of cell migration GO:0030336 59 0.034
myotube differentiation GO:0014902 105 0.034
Mouse
nucleoside phosphate biosynthetic process GO:1901293 79 0.034
cdc42 protein signal transduction GO:0032488 0 0.034
regulation of protein localization GO:0032880 231 0.034
regulation of receptor activity GO:0010469 41 0.034
meiotic cell cycle GO:0051321 122 0.034
cellular response to nutrient levels GO:0031669 64 0.034
sphingolipid metabolic process GO:0006665 45 0.033
positive regulation of reactive oxygen species metabolic process GO:2000379 11 0.033
triglyceride metabolic process GO:0006641 51 0.033
negative regulation of cell development GO:0010721 169 0.033
Mouse
axon guidance GO:0007411 141 0.033
Mouse
intracellular lipid transport GO:0032365 3 0.033
nucleoside phosphate catabolic process GO:1901292 222 0.033
guanosine containing compound catabolic process GO:1901069 144 0.033
protein catabolic process GO:0030163 221 0.033
erythrocyte differentiation GO:0030218 88 0.033
negative regulation of protein phosphorylation GO:0001933 126 0.033
epithelial cell development GO:0002064 159 0.033
organic hydroxy compound biosynthetic process GO:1901617 77 0.032
calcium ion transport GO:0006816 159 0.032
multicellular organismal homeostasis GO:0048871 164 0.032
actin filament based movement GO:0030048 23 0.032
receptor mediated endocytosis GO:0006898 51 0.032
positive regulation of lipid transport GO:0032370 22 0.032
immune effector process GO:0002252 321 0.032
regulation of cell cycle GO:0051726 281 0.032
genitalia development GO:0048806 37 0.032
glomerular mesangial cell proliferation GO:0072110 3 0.032
positive regulation of smooth muscle cell migration GO:0014911 4 0.032
ensheathment of neurons GO:0007272 76 0.032
neutral lipid metabolic process GO:0006638 57 0.032
positive regulation of angiogenesis GO:0045766 46 0.032
regulation of sterol transport GO:0032371 17 0.032
regulation of membrane protein ectodomain proteolysis GO:0051043 3 0.032
cholesterol metabolic process GO:0008203 56 0.031
lymphocyte proliferation GO:0046651 164 0.031
muscle system process GO:0003012 141 0.031
response to molecule of bacterial origin GO:0002237 143 0.031
cellular response to interferon alpha GO:0035457 4 0.031
nephron development GO:0072006 109 0.031
negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:2000162 1 0.031
locomotory behavior GO:0007626 195 0.031
cerebellum development GO:0021549 77 0.031
regulation of gtp catabolic process GO:0033124 113 0.031
salivary gland morphogenesis GO:0007435 33 0.031
Mouse
leukocyte chemotaxis GO:0030595 69 0.031
nucleocytoplasmic transport GO:0006913 139 0.031
epithelial cell migration GO:0010631 63 0.031
regulation of anion transport GO:0044070 27 0.030
respiratory system development GO:0060541 190 0.030
interferon gamma production GO:0032609 67 0.030
atp metabolic process GO:0046034 75 0.030
purine nucleoside triphosphate metabolic process GO:0009144 226 0.030
negative regulation of cholesterol efflux GO:0090370 4 0.030
monocarboxylic acid transport GO:0015718 44 0.030
response to oxygen levels GO:0070482 62 0.030
ubiquitin dependent protein catabolic process GO:0006511 129 0.030
gliogenesis GO:0042063 141 0.030
c21 steroid hormone biosynthetic process GO:0006700 3 0.030
regulation of platelet derived growth factor receptor signaling pathway GO:0010640 9 0.030
action potential GO:0001508 78 0.030
embryonic placenta development GO:0001892 98 0.029
positive regulation of programmed cell death GO:0043068 218 0.029
ameboidal type cell migration GO:0001667 128 0.029
positive regulation of cellular protein catabolic process GO:1903364 34 0.029
regulation of axon extension GO:0030516 43 0.029
Mouse
regulation of metanephric mesenchymal cell migration GO:2000589 2 0.029
cellular response to monosaccharide stimulus GO:0071326 47 0.029
cation transmembrane transport GO:0098655 266 0.029
cholesterol transport GO:0030301 38 0.029

Mertk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.367
inherited metabolic disorder DOID:655 0 0.367
sensory system disease DOID:0050155 0 0.074
Human
disease of anatomical entity DOID:7 0 0.074
Human
eye and adnexa disease DOID:1492 0 0.074
Human
nervous system disease DOID:863 0 0.074
Human
eye disease DOID:5614 0 0.074
Human
immune system disease DOID:2914 0 0.052
retinal disease DOID:5679 0 0.051
Human
central nervous system disease DOID:331 0 0.039
neurodegenerative disease DOID:1289 0 0.031
disease of mental health DOID:150 0 0.029