Mus musculus

94 known processes

Pomc

pro-opiomelanocortin-alpha

(Aliases: BE,alpha-MSH,alphaMSH,gamma-MSH,Pomc-1,Pomc1,ACTH,beta-MSH)

Pomc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuropeptide signaling pathway GO:0007218 19 0.957
Zebrafish
melanin biosynthetic process GO:0042438 10 0.932
pigmentation GO:0043473 71 0.923
Zebrafish
feeding behavior GO:0007631 62 0.914
pigment biosynthetic process GO:0046148 26 0.828
positive regulation of nucleotide biosynthetic process GO:0030810 26 0.795
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 24 0.781
secondary metabolite biosynthetic process GO:0044550 11 0.755
melanin metabolic process GO:0006582 12 0.743
regulation of hormone levels GO:0010817 211 0.690
regulation of feeding behavior GO:0060259 3 0.678
amide transport GO:0042886 138 0.670
nucleotide biosynthetic process GO:0009165 78 0.663
response to peptide GO:1901652 136 0.654
regulation of nucleotide biosynthetic process GO:0030808 34 0.631
response to peptide hormone GO:0043434 127 0.555
cellular response to organonitrogen compound GO:0071417 145 0.529
regulation of protein kinase c signaling GO:0090036 5 0.514
cyclic nucleotide metabolic process GO:0009187 59 0.510
forebrain development GO:0030900 302 0.502
phenol containing compound biosynthetic process GO:0046189 21 0.499
regulation of catecholamine secretion GO:0050433 12 0.498
insulin secretion GO:0030073 89 0.495
peptide transport GO:0015833 133 0.488
response to organonitrogen compound GO:0010243 246 0.473
protein kinase c signaling GO:0070528 7 0.469
ribose phosphate biosynthetic process GO:0046390 59 0.454
regulation of peptide transport GO:0090087 91 0.452
camp biosynthetic process GO:0006171 31 0.427
cyclic purine nucleotide metabolic process GO:0052652 43 0.421
response to alcohol GO:0097305 48 0.416
peptide secretion GO:0002790 114 0.410
divalent metal ion transport GO:0070838 172 0.410
hormone secretion GO:0046879 128 0.408
monosaccharide metabolic process GO:0005996 106 0.394
response to corticosterone GO:0051412 1 0.388
peptide hormone secretion GO:0030072 109 0.382
glucose homeostasis GO:0042593 128 0.380
glucocorticoid biosynthetic process GO:0006704 5 0.367
g protein coupled receptor signaling pathway GO:0007186 243 0.364
Zebrafish
ribonucleotide metabolic process GO:0009259 291 0.363
gland development GO:0048732 330 0.360
vitamin d catabolic process GO:0042369 1 0.354
response to insulin GO:0032868 100 0.344
cellular response to organic cyclic compound GO:0071407 87 0.343
positive regulation of purine nucleotide biosynthetic process GO:1900373 26 0.329
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.325
carbohydrate derivative biosynthetic process GO:1901137 183 0.318
catecholamine secretion GO:0050432 15 0.315
protein kinase a signaling GO:0010737 7 0.314
regulation of hormone secretion GO:0046883 88 0.312
digestion GO:0007586 40 0.310
purine nucleotide biosynthetic process GO:0006164 65 0.308
synaptic transmission GO:0007268 329 0.307
sensory perception of pain GO:0019233 47 0.305
cellular response to peptide GO:1901653 92 0.301
nucleotide metabolic process GO:0009117 332 0.295
regulation of blood pressure GO:0008217 93 0.292
response to alkaloid GO:0043279 34 0.291
regulation of glucocorticoid secretion GO:2000849 5 0.289
cellular response to peptide hormone stimulus GO:0071375 92 0.286
ribonucleotide biosynthetic process GO:0009260 59 0.285
regulation of camp metabolic process GO:0030814 30 0.275
response to inactivity GO:0014854 4 0.255
eye photoreceptor cell differentiation GO:0001754 41 0.251
glucose metabolic process GO:0006006 92 0.251
pigment granule localization GO:0051875 13 0.249
Zebrafish
alpha amino acid metabolic process GO:1901605 59 0.248
regulation of purine nucleotide metabolic process GO:1900542 169 0.241
purine nucleotide metabolic process GO:0006163 302 0.239
response to corticosteroid GO:0031960 20 0.239
regulation of nucleotide metabolic process GO:0006140 169 0.230
eye photoreceptor cell development GO:0042462 31 0.222
fat soluble vitamin catabolic process GO:0042363 1 0.221
response to organic cyclic compound GO:0014070 198 0.219
nucleoside phosphate biosynthetic process GO:1901293 79 0.217
purine ribonucleotide metabolic process GO:0009150 290 0.215
negative regulation of hormone secretion GO:0046888 20 0.215
positive regulation of purine nucleotide metabolic process GO:1900544 114 0.207
photoreceptor cell differentiation GO:0046530 52 0.196
nucleobase containing small molecule metabolic process GO:0055086 352 0.194
nitrogen compound transport GO:0071705 271 0.194
purine containing compound biosynthetic process GO:0072522 70 0.193
anatomical structure homeostasis GO:0060249 145 0.189
positive regulation of camp metabolic process GO:0030816 19 0.188
nucleoside metabolic process GO:0009116 246 0.184
response to mineralocorticoid GO:0051385 1 0.182
response to food GO:0032094 17 0.179
hormone metabolic process GO:0042445 86 0.177
cellular response to hormone stimulus GO:0032870 150 0.174
positive regulation of cyclic nucleotide metabolic process GO:0030801 24 0.173
norepinephrine transport GO:0015874 2 0.172
cellular response to lipid GO:0071396 145 0.170
sensory perception GO:0007600 245 0.166
male gamete generation GO:0048232 285 0.163
camp metabolic process GO:0046058 40 0.163
regulation of purine nucleotide biosynthetic process GO:1900371 34 0.163
pigment metabolic process GO:0042440 32 0.162
response to drug GO:0042493 75 0.153
response to cocaine GO:0042220 14 0.150
regulation of camp biosynthetic process GO:0030817 25 0.147
response to steroid hormone GO:0048545 56 0.145
long term synaptic potentiation GO:0060291 25 0.145
response to glucocorticoid GO:0051384 20 0.145
regulation of transferase activity GO:0051338 263 0.144
organophosphate biosynthetic process GO:0090407 122 0.143
phenol containing compound metabolic process GO:0018958 60 0.138
secondary metabolic process GO:0019748 18 0.138
purine ribonucleotide biosynthetic process GO:0009152 59 0.138
response to amine GO:0014075 16 0.137
regulation of cyclic nucleotide biosynthetic process GO:0030802 31 0.137
negative regulation of peptide secretion GO:0002792 16 0.132
multicellular organism growth GO:0035264 161 0.131
renal system process GO:0003014 48 0.131
response to pain GO:0048265 26 0.128
organic hydroxy compound biosynthetic process GO:1901617 77 0.127
hexose metabolic process GO:0019318 98 0.127
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 54 0.126
positive regulation of bone remodeling GO:0046852 13 0.126
nucleoside phosphate metabolic process GO:0006753 338 0.126
regulation of protein kinase a signaling GO:0010738 6 0.125
progesterone metabolic process GO:0042448 4 0.124
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 26 0.124
cyclic nucleotide biosynthetic process GO:0009190 44 0.123
photoreceptor cell development GO:0042461 40 0.122
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 30 0.122
positive regulation of camp biosynthetic process GO:0030819 19 0.121
generation of precursor metabolites and energy GO:0006091 103 0.119
skin development GO:0043588 220 0.118
oxidation reduction process GO:0055114 342 0.117
catecholamine metabolic process GO:0006584 30 0.115
negative regulation of cytosolic calcium ion concentration GO:0051481 2 0.114
circadian rhythm GO:0007623 114 0.114
rhythmic process GO:0048511 174 0.113
divalent inorganic cation transport GO:0072511 178 0.111
positive regulation of ion transport GO:0043270 65 0.111
dopamine secretion GO:0014046 9 0.111
bone remodeling GO:0046849 53 0.110
regulation of cellular carbohydrate metabolic process GO:0010675 75 0.109
corticosterone secretion GO:0035934 3 0.109
protein maturation GO:0051604 176 0.108
cellular response to insulin stimulus GO:0032869 78 0.106
regulation of ion transmembrane transporter activity GO:0032412 54 0.106
regulation of peptide hormone secretion GO:0090276 75 0.104
carbohydrate homeostasis GO:0033500 128 0.104
norepinephrine secretion GO:0048243 2 0.103
negative regulation of peptide hormone secretion GO:0090278 16 0.103
regulation of dopamine secretion GO:0014059 9 0.103
protein kinase b signaling GO:0043491 74 0.103
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.103
organic hydroxy compound metabolic process GO:1901615 203 0.102
smooth muscle contraction GO:0006939 44 0.101
adult feeding behavior GO:0008343 9 0.098
cellular response to glucocorticoid stimulus GO:0071385 13 0.097
regulation of circadian sleep wake cycle GO:0042749 3 0.095
melanosome organization GO:0032438 8 0.095
positive regulation of homeostatic process GO:0032846 64 0.094
regulation of secretion by cell GO:1903530 249 0.094
positive regulation of protein kinase a signaling GO:0010739 2 0.094
locomotory behavior GO:0007626 195 0.093
cognition GO:0050890 149 0.092
neuron neuron synaptic transmission GO:0007270 69 0.091
cellular chemical homeostasis GO:0055082 215 0.091
negative regulation of blood pressure GO:0045776 22 0.084
acid secretion GO:0046717 33 0.084
adenylate cyclase activating dopamine receptor signaling pathway GO:0007191 7 0.083
response to estrogen GO:0043627 24 0.083
regulation of adrenergic receptor signaling pathway GO:0071877 4 0.083
organic hydroxy compound transport GO:0015850 93 0.082
negative regulation of phosphorylation GO:0042326 166 0.082
response to testosterone GO:0033574 3 0.081
blood circulation GO:0008015 195 0.080
response to lipopolysaccharide GO:0032496 128 0.080
sensory perception of umami taste GO:0050917 4 0.079
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 3 0.077
gonad development GO:0008406 141 0.076
positive regulation of transferase activity GO:0051347 167 0.075
regulation of circadian sleep wake cycle sleep GO:0045187 3 0.074
cellular lipid metabolic process GO:0044255 323 0.074
positive regulation of nucleotide metabolic process GO:0045981 114 0.074
dna metabolic process GO:0006259 303 0.073
regulation of cell motility GO:2000145 236 0.073
hair follicle development GO:0001942 85 0.072
adrenal gland development GO:0030325 18 0.071
regulation of ion transmembrane transport GO:0034765 119 0.071
circadian sleep wake cycle GO:0042745 5 0.071
regulation of protein kinase b signaling GO:0051896 56 0.069
response to nutrient levels GO:0031667 109 0.069
purine containing compound metabolic process GO:0072521 311 0.069
endocrine system development GO:0035270 98 0.067
multicellular organismal response to stress GO:0033555 62 0.067
tissue homeostasis GO:0001894 115 0.066
cellular response to steroid hormone stimulus GO:0071383 33 0.066
eating behavior GO:0042755 15 0.066
multi multicellular organism process GO:0044706 109 0.065
regulation of system process GO:0044057 200 0.065
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 4 0.065
positive regulation of mapk cascade GO:0043410 170 0.064
limbic system development GO:0021761 72 0.063
development of primary sexual characteristics GO:0045137 143 0.063
establishment of melanosome localization GO:0032401 11 0.063
muscle system process GO:0003012 141 0.061
memory GO:0007613 58 0.060
organonitrogen compound biosynthetic process GO:1901566 192 0.060
steroid metabolic process GO:0008202 119 0.060
musculoskeletal movement spinal reflex action GO:0050883 3 0.060
epinephrine transport GO:0048241 1 0.059
purine ribonucleoside metabolic process GO:0046128 241 0.059
negative regulation of secretion GO:0051048 61 0.059
diterpenoid metabolic process GO:0016101 24 0.058
regulation of response to food GO:0032095 10 0.058
cellular response to catecholamine stimulus GO:0071870 3 0.058
regulation of body fluid levels GO:0050878 162 0.058
regulation of heart contraction GO:0008016 77 0.057
regulation of glucagon secretion GO:0070092 2 0.057
regulation of secretion GO:0051046 274 0.056
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 20 0.056
cellular response to ammonium ion GO:0071242 2 0.056
negative regulation of secretion by cell GO:1903531 54 0.056
regulation of calcium ion transport GO:0051924 69 0.055
sensory organ morphogenesis GO:0090596 242 0.055
axonogenesis GO:0007409 274 0.055
negative regulation of calcium ion transmembrane transport GO:1903170 1 0.055
neuron migration GO:0001764 122 0.055
negative regulation of neuron death GO:1901215 98 0.054
regulation of synaptic plasticity GO:0048167 87 0.054
monocarboxylic acid metabolic process GO:0032787 191 0.053
cellular homeostasis GO:0019725 240 0.053
regulation of metal ion transport GO:0010959 106 0.053
calcium ion transport GO:0006816 159 0.053
response to radiation GO:0009314 165 0.053
protein processing GO:0016485 163 0.052
regulation of androgen receptor signaling pathway GO:0060765 3 0.052
diencephalon development GO:0021536 63 0.051
dopamine biosynthetic process GO:0042416 6 0.051
regulation of cell projection organization GO:0031344 206 0.051
response to catecholamine GO:0071869 4 0.051
adrenergic receptor signaling pathway GO:0071875 13 0.051
cellular divalent inorganic cation homeostasis GO:0072503 127 0.050
positive regulation of sodium ion transmembrane transport GO:1902307 4 0.050
cellular ketone metabolic process GO:0042180 84 0.050
central nervous system neuron development GO:0021954 67 0.050
aldosterone metabolic process GO:0032341 2 0.050
melanosome transport GO:0032402 11 0.049
nucleoside phosphate catabolic process GO:1901292 222 0.049
cell growth GO:0016049 130 0.049
response to ammonium ion GO:0060359 21 0.049
negative regulation of phosphate metabolic process GO:0045936 184 0.049
myotube differentiation GO:0014902 105 0.049
telencephalon development GO:0021537 186 0.048
regulation of protein kinase activity GO:0045859 232 0.048
regulation of blood volume by renal aldosterone GO:0002017 1 0.048
pallium development GO:0021543 120 0.048
multicellular organismal homeostasis GO:0048871 164 0.048
gastric acid secretion GO:0001696 6 0.047
intracellular receptor signaling pathway GO:0030522 74 0.047
cellular response to corticosteroid stimulus GO:0071384 13 0.047
organic cyclic compound catabolic process GO:1901361 295 0.047
transmembrane transport GO:0055085 412 0.047
tissue remodeling GO:0048771 102 0.046
carboxylic acid catabolic process GO:0046395 51 0.046
skeletal system morphogenesis GO:0048705 203 0.045
fear response GO:0042596 33 0.045
response to extracellular stimulus GO:0009991 127 0.044
positive regulation of peptide hormone secretion GO:0090277 31 0.044
dopamine receptor signaling pathway GO:0007212 16 0.044
phototransduction GO:0007602 17 0.044
regulation of corticosterone secretion GO:2000852 2 0.044
positive regulation of protein kinase b signaling GO:0051897 32 0.043
divalent inorganic cation homeostasis GO:0072507 138 0.043
pigment granule organization GO:0048753 9 0.043
negative regulation of cation channel activity GO:2001258 1 0.042
cellular nitrogen compound catabolic process GO:0044270 280 0.042
lipid catabolic process GO:0016042 69 0.042
connective tissue development GO:0061448 179 0.042
digestive system development GO:0055123 200 0.042
regulation of amine transport GO:0051952 21 0.041
cellular metal ion homeostasis GO:0006875 151 0.041
regulation of steroid hormone biosynthetic process GO:0090030 4 0.041
lipid transport GO:0006869 98 0.041
negative regulation of growth GO:0045926 99 0.040
regulation of glucose metabolic process GO:0010906 60 0.040
cell substrate adhesion GO:0031589 130 0.040
ribose phosphate metabolic process GO:0019693 291 0.040
glucagon secretion GO:0070091 3 0.040
positive regulation of renal sodium excretion GO:0035815 2 0.040
mineralocorticoid biosynthetic process GO:0006705 1 0.039
regulation of cell migration GO:0030334 219 0.039
positive regulation of protein kinase c signaling GO:0090037 1 0.039
response to inorganic substance GO:0010035 96 0.039
cellular response to acid chemical GO:0071229 68 0.039
regulation of hydrolase activity GO:0051336 246 0.039
hormone mediated signaling pathway GO:0009755 23 0.038
hindbrain development GO:0030902 128 0.038
amine transport GO:0015837 21 0.038
glutamate receptor signaling pathway GO:0007215 35 0.038
forebrain generation of neurons GO:0021872 63 0.038
genetic imprinting GO:0071514 27 0.038
vesicle localization GO:0051648 86 0.038
Zebrafish
regulation of kinase activity GO:0043549 249 0.038
circulatory system process GO:0003013 197 0.038
nucleoside triphosphate metabolic process GO:0009141 230 0.037
fat soluble vitamin biosynthetic process GO:0042362 4 0.037
monoamine transport GO:0015844 33 0.037
response to monosaccharide GO:0034284 67 0.037
response to nicotine GO:0035094 6 0.037
developmental growth involved in morphogenesis GO:0060560 138 0.036
posttranscriptional regulation of gene expression GO:0010608 155 0.036
detection of light stimulus GO:0009583 25 0.036
negative regulation of calcium ion transmembrane transporter activity GO:1901020 1 0.036
calcium ion homeostasis GO:0055074 127 0.036
microtubule based process GO:0007017 236 0.035
cellular response to lipopolysaccharide GO:0071222 77 0.035
regulation of digestive system process GO:0044058 13 0.035
bone resorption GO:0045453 38 0.035
small molecule catabolic process GO:0044282 71 0.035
spermatogenesis GO:0007283 284 0.035
establishment of organelle localization GO:0051656 122 0.035
response to vitamin d GO:0033280 3 0.034
regulation of peptide secretion GO:0002791 77 0.034
cellular response to carbohydrate stimulus GO:0071322 50 0.034
asymmetric stem cell division GO:0098722 3 0.034
cation transport GO:0006812 399 0.034
g protein coupled receptor signaling pathway involved in heart process GO:0086103 4 0.034
negative regulation of molecular function GO:0044092 258 0.033
myeloid cell differentiation GO:0030099 233 0.033
modification dependent protein catabolic process GO:0019941 133 0.033
body fluid secretion GO:0007589 53 0.032
positive regulation of dopamine uptake involved in synaptic transmission GO:0051586 2 0.032
regulation of bone resorption GO:0045124 24 0.032
energy reserve metabolic process GO:0006112 39 0.032
c21 steroid hormone biosynthetic process GO:0006700 3 0.032
positive regulation of vasoconstriction GO:0045907 4 0.032
regulation of urine volume GO:0035809 6 0.032
nucleoside triphosphate catabolic process GO:0009143 205 0.032
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.032
positive regulation of leukocyte mediated immunity GO:0002705 70 0.032
negative regulation of cellular protein metabolic process GO:0032269 247 0.031
regulation of blood circulation GO:1903522 93 0.031
regulation of intracellular transport GO:0032386 159 0.031
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.031
vitamin catabolic process GO:0009111 1 0.030
response to molecule of bacterial origin GO:0002237 143 0.030
anion transport GO:0006820 177 0.030
cellular response to ketone GO:1901655 12 0.030
conditioned taste aversion GO:0001661 4 0.030
cellular amino acid metabolic process GO:0006520 103 0.030
negative regulation of homeostatic process GO:0032845 71 0.030
muscle contraction GO:0006936 101 0.030
spermatid differentiation GO:0048515 115 0.029
cellular protein complex assembly GO:0043623 116 0.029
ribonucleoside triphosphate metabolic process GO:0009199 220 0.029
mapk cascade GO:0000165 281 0.029
respiratory tube development GO:0030323 167 0.029
negative regulation of sterol transport GO:0032372 4 0.029
regulation of protein catabolic process GO:0042176 108 0.029
regulation of b cell activation GO:0050864 81 0.029
regulation of receptor activity GO:0010469 41 0.029
regulation of steroid biosynthetic process GO:0050810 26 0.029
gluconeogenesis GO:0006094 39 0.029
regulation of transmembrane transport GO:0034762 128 0.029
sperm motility GO:0030317 47 0.028
catecholamine transport GO:0051937 21 0.028
regulation of lipid metabolic process GO:0019216 118 0.028
cellular lipid catabolic process GO:0044242 52 0.028
response to ethanol GO:0045471 18 0.028
spermatid development GO:0007286 108 0.028
regulation of voltage gated calcium channel activity GO:1901385 4 0.028
positive regulation of kinase activity GO:0033674 155 0.028
cellular response to epinephrine stimulus GO:0071872 3 0.028
regulation of ion transport GO:0043269 215 0.027
cellular response to inorganic substance GO:0071241 37 0.027
positive regulation of cell death GO:0010942 224 0.027
regulation of dopamine uptake involved in synaptic transmission GO:0051584 2 0.027
insulin receptor signaling pathway GO:0008286 49 0.027
glial cell differentiation GO:0010001 131 0.027
regulation of cellular ketone metabolic process GO:0010565 66 0.027
coagulation GO:0050817 78 0.026
negative regulation of cell development GO:0010721 169 0.026
negative regulation of insulin secretion GO:0046676 14 0.026
organic anion transport GO:0015711 137 0.026
glycosyl compound metabolic process GO:1901657 246 0.026
positive regulation of sodium ion transport GO:0010765 13 0.026
aldosterone biosynthetic process GO:0032342 1 0.026
positive regulation of glial cell proliferation GO:0060252 4 0.026
canonical wnt signaling pathway GO:0060070 130 0.026
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.026
morphogenesis of a branching structure GO:0001763 203 0.026
positive regulation of transmembrane transport GO:0034764 29 0.026
response to light stimulus GO:0009416 135 0.026
maternal process involved in female pregnancy GO:0060135 32 0.026
circadian regulation of gene expression GO:0032922 48 0.026
dibenzo p dioxin metabolic process GO:0018894 1 0.026
microtubule cytoskeleton organization GO:0000226 157 0.025
ossification GO:0001503 216 0.025
developmental cell growth GO:0048588 84 0.025
maintenance of location GO:0051235 89 0.025
positive regulation of tissue remodeling GO:0034105 19 0.025
regulation of gluconeogenesis GO:0006111 30 0.025
negative regulation of dna replication GO:0008156 4 0.025
regulation of neurotransmitter transport GO:0051588 35 0.025
sequestering of calcium ion GO:0051208 18 0.025
cellular response to growth factor stimulus GO:0071363 197 0.025
prostate gland development GO:0030850 48 0.025
negative regulation of action potential GO:0045759 1 0.025
platelet activation GO:0030168 40 0.025
positive regulation of neuron projection development GO:0010976 79 0.025
proteoglycan metabolic process GO:0006029 38 0.025
negative regulation of immune system process GO:0002683 209 0.025
response to morphine GO:0043278 9 0.025
response to iron ion GO:0010039 4 0.024
regulation of lyase activity GO:0051339 13 0.024
melanocyte differentiation GO:0030318 25 0.024
circadian sleep wake cycle non rem sleep GO:0042748 2 0.024
positive regulation of behavior GO:0048520 40 0.024
tube lumen cavitation GO:0060605 5 0.024
regulation of circadian rhythm GO:0042752 58 0.024
cellular carbohydrate metabolic process GO:0044262 119 0.024
positive regulation of protein modification process GO:0031401 299 0.023
positive regulation of cytosolic calcium ion concentration involved in phospholipase c activating g protein coupled signaling pathway GO:0051482 4 0.023
positive regulation of apoptotic process GO:0043065 217 0.023
regulation of insulin receptor signaling pathway GO:0046626 21 0.023
g protein coupled acetylcholine receptor signaling pathway GO:0007213 4 0.023
negative regulation of cholesterol efflux GO:0090370 4 0.023
regulation of norepinephrine secretion GO:0014061 2 0.023
melanosome localization GO:0032400 12 0.023
Zebrafish
cell adhesion GO:0007155 329 0.023
muscle adaptation GO:0043500 39 0.023
epinephrine secretion GO:0048242 1 0.023
vasodilation GO:0042311 28 0.023
cellular response to cadmium ion GO:0071276 3 0.023
reactive oxygen species biosynthetic process GO:1903409 8 0.023
cytosolic calcium ion homeostasis GO:0051480 70 0.023
sequestering of metal ion GO:0051238 19 0.023
heart contraction GO:0060047 93 0.023
regulation of membrane potential GO:0042391 192 0.023
response to growth factor GO:0070848 198 0.022
negative regulation of phosphorus metabolic process GO:0010563 184 0.022
regulation of organelle organization GO:0033043 289 0.022
negative regulation of protein phosphorylation GO:0001933 126 0.022
positive regulation of peptide secretion GO:0002793 33 0.022
regulation of nucleoside metabolic process GO:0009118 130 0.022
isoprenoid metabolic process GO:0006720 29 0.022
regulation of transporter activity GO:0032409 57 0.022
organic acid catabolic process GO:0016054 51 0.022
regulation of carbohydrate biosynthetic process GO:0043255 40 0.022
microtubule based movement GO:0007018 84 0.022
second messenger mediated signaling GO:0019932 73 0.022
asymmetric neuroblast division GO:0055059 1 0.022
regulation of leukocyte differentiation GO:1902105 159 0.022
metencephalon development GO:0022037 89 0.021
cell division GO:0051301 120 0.021
visual perception GO:0007601 52 0.021
positive regulation of insulin secretion GO:0032024 26 0.021
regulation of lymphocyte proliferation GO:0050670 117 0.021
leukocyte mediated immunity GO:0002443 174 0.021
dna repair GO:0006281 107 0.021
response to oxygen levels GO:0070482 62 0.021
regulation of endocytosis GO:0030100 69 0.021
multicellular organismal signaling GO:0035637 91 0.021
negative regulation of fatty acid oxidation GO:0046322 5 0.021
response to acid chemical GO:0001101 111 0.021
cellular response to antibiotic GO:0071236 4 0.021
spinal cord motor neuron differentiation GO:0021522 35 0.021
response to amphetamine GO:0001975 16 0.021
serotonin transport GO:0006837 11 0.021
action potential GO:0001508 78 0.020
regulation of cell growth GO:0001558 91 0.020
carbohydrate catabolic process GO:0016052 32 0.020
cellular response to monoamine stimulus GO:0071868 3 0.020
circadian sleep wake cycle rem sleep GO:0042747 1 0.020
monosaccharide biosynthetic process GO:0046364 44 0.020
spinal cord development GO:0021510 81 0.020
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.020
lipid biosynthetic process GO:0008610 179 0.020
regulation of catecholamine uptake involved in synaptic transmission GO:0051940 2 0.020
dicarboxylic acid metabolic process GO:0043648 18 0.020
regulation of carbohydrate metabolic process GO:0006109 75 0.020
developmental pigmentation GO:0048066 40 0.020
cation transmembrane transport GO:0098655 266 0.020
fatty acid metabolic process GO:0006631 121 0.019
regulation of serotonin uptake GO:0051611 2 0.019
carbohydrate biosynthetic process GO:0016051 74 0.019
positive regulation of ion transmembrane transport GO:0034767 24 0.019
cerebellum development GO:0021549 77 0.019
respiratory system development GO:0060541 190 0.019
development of primary male sexual characteristics GO:0046546 88 0.019
purine ribonucleoside catabolic process GO:0046130 205 0.019
positive regulation of gtpase activity GO:0043547 85 0.019
epidermis development GO:0008544 187 0.019

Pomc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.056
disease of anatomical entity DOID:7 0 0.054
nervous system disease DOID:863 0 0.054
inherited metabolic disorder DOID:655 0 0.031
central nervous system disease DOID:331 0 0.028
mouth disease DOID:403 0 0.023
gastrointestinal system disease DOID:77 0 0.023
sensory system disease DOID:0050155 0 0.020
eye and adnexa disease DOID:1492 0 0.020