IMP
Process View
aldosterone biosynthetic process
The chemical reactions and pathways resulting in the formation of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "aldosterone biosynthetic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Phex | phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets) | 0.585 | ||
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.258 | ||
| Slc12a1 | solute carrier family 12, member 1 | 0.147 | ||
| Hoxa10 | homeobox A10 | 0.126 | ||
| Bmp7 | bone morphogenetic protein 7 | 0.099 | ||
| Runx2 | runt related transcription factor 2 | 0.087 | ||
| Bmp4 | bone morphogenetic protein 4 | 0.076 | ||
| Prrx1 | paired related homeobox 1 | 0.057 | ||
| Fgfr3 | fibroblast growth factor receptor 3 | 0.053 | ||
| Acvr1 | activin A receptor, type 1 | 0.051 | ||
| Cyp11a1 | cytochrome P450, family 11, subfamily a, polypeptide 1 | 0.048 | Mouse | |
| Nostrin | nitric oxide synthase trafficker | 0.043 | ||
| Tbx15 | T-box 15 | 0.042 | ||
| Nanog | Nanog homeobox | 0.041 | ||
| Tgfb2 | transforming growth factor, beta 2 | 0.039 | ||
| Mc2r | melanocortin 2 receptor | 0.035 | ||
| Lhcgr | luteinizing hormone/choriogonadotropin receptor | 0.035 | ||
| Agtr1a | angiotensin II receptor, type 1a | 0.034 | ||
| Htt | huntingtin | 0.030 | ||
| Sox9 | SRY-box containing gene 9 | 0.030 | ||
| Pomc | pro-opiomelanocortin-alpha | 0.026 | ||
| Ren1 | renin 1 structural | 0.025 | ||
| Tgfbr3 | transforming growth factor, beta receptor III | 0.024 | ||
| Cyp11b2 | cytochrome P450, family 11, subfamily b, polypeptide 2 | 0.024 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.022 | ||
| Fgf23 | fibroblast growth factor 23 | 0.021 | ||
| Ar | androgen receptor | 0.021 | ||
| Fstl1 | follistatin-like 1 | 0.021 | ||
| Nr0b1 | nuclear receptor subfamily 0, group B, member 1 | 0.020 | ||
| Timp2 | tissue inhibitor of metalloproteinase 2 | 0.019 | ||
| Prrx2 | paired related homeobox 2 | 0.018 | ||
| Itga8 | integrin alpha 8 | 0.018 | ||
| Vdr | vitamin D receptor | 0.017 | ||
| Xrn1 | 5'-3' exoribonuclease 1 | 0.017 | ||
| Agt | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.017 | ||
| Lrp2 | low density lipoprotein receptor-related protein 2 | 0.017 | ||
| Ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 0.016 | ||
| Smad1 | MAD homolog 1 (Drosophila) | 0.015 | ||
| Slc34a1 | solute carrier family 34 (sodium phosphate), member 1 | 0.015 | ||
| Nr5a1 | nuclear receptor subfamily 5, group A, member 1 | 0.015 | ||
| Bgn | biglycan | 0.014 | ||
| Gucy1a3 | guanylate cyclase 1, soluble, alpha 3 | 0.013 | ||
| Kl | klotho | 0.013 | ||
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.013 | ||
| Pde8b | phosphodiesterase 8B | 0.012 | ||
| Ctgf | connective tissue growth factor | 0.012 | ||
| Msx1 | homeobox, msh-like 1 | 0.012 | ||
| Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.012 | ||
| Ddx6 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 | 0.012 | ||
| Wnt5a | wingless-related MMTV integration site 5A | 0.012 | ||
| Ptch1 | patched homolog 1 | 0.012 | ||
| Crh | corticotropin releasing hormone | 0.011 | ||
| Casr | calcium-sensing receptor | 0.011 | ||
| Alx1 | ALX homeobox 1 | 0.011 | ||
| Sp1 | trans-acting transcription factor 1 | 0.011 | ||
| Wnk4 | WNK lysine deficient protein kinase 4 | 0.011 | ||
| Umod | uromodulin | 0.011 | ||
| Acsm2 | acyl-CoA synthetase medium-chain family member 2 | 0.011 | ||
| Fgfrl1 | fibroblast growth factor receptor-like 1 | 0.011 | ||
| Angpt1 | angiopoietin 1 | 0.011 | ||
| Slc23a2 | solute carrier family 23 (nucleobase transporters), member 2 | 0.010 |