IMP

Process View

Mus musculus

16 genes annotated in mouse

Multi-species View

negative regulation of peptide secretion

GO:0002792

Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of peptide secretion"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of peptide secretion" (in gray)

Name	Description	Probability	Func Analog Organism
Tgfbr2	transforming growth factor, beta receptor II	0.769	Mouse
Lep	leptin	0.704
Nos3	nitric oxide synthase 3, endothelial cell	0.692
Esr1	estrogen receptor 1 (alpha)	0.604
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.537
Lepr	leptin receptor	0.512
H2-Aa	histocompatibility 2, class II antigen A, alpha	0.484
Insr	insulin receptor	0.481
Prlr	prolactin receptor	0.434
Ghr	growth hormone receptor	0.342
Mup10	major urinary protein 10	0.333	Mouse
Fshr	follicle stimulating hormone receptor	0.326
Mup19	major urinary protein 19	0.312	Mouse
H2-Eb1	histocompatibility 2, class II antigen E beta	0.259
LOC100048884	novel member of the major urinary protein (Mup) gene family	0.221	Mouse
Ar	androgen receptor	0.216
Nos1	nitric oxide synthase 1, neuronal	0.205	Rat
Irs2	insulin receptor substrate 2	0.197
Pkm2	pyruvate kinase, muscle	0.189
Fst	follistatin	0.179
Cav1	caveolin 1, caveolae protein	0.175
Mup9	major urinary protein 9	0.171	Mouse
Mup1	major urinary protein 1	0.169
Tgfbr1	transforming growth factor, beta receptor I	0.138	Mouse
Aldoa	aldolase A, fructose-bisphosphate	0.135
Pomc	pro-opiomelanocortin-alpha	0.132
Pim1	proviral integration site 1	0.128	Mouse
Gata4	GATA binding protein 4	0.112
LOC100048885	major urinary protein LOC100048885	0.096	Mouse
Inhba	inhibin beta-A	0.093	Mouse
Mup7	major urinary protein 7	0.091	Mouse
Mup12	major urinary protein 12	0.089	Mouse
Amhr2	anti-Mullerian hormone type 2 receptor	0.082	Mouse
Esr2	estrogen receptor 2 (beta)	0.079
Mup17	major urinary protein 17	0.077
Mup2	major urinary protein 2	0.077	Mouse
Ldlr	low density lipoprotein receptor	0.077
Mup13	major urinary protein 13	0.075
Mup11	major urinary protein 11	0.074	Mouse
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.072
Htt	huntingtin	0.070
Mup14	major urinary protein 14	0.068	Mouse
Mup8	major urinary protein 8	0.067	Mouse
Mup3	major urinary protein 3	0.062	Mouse
Mup5	major urinary protein 5	0.060	Mouse
Pnpla2	patatin-like phospholipase domain containing 2	0.056
Mup15	major urinary protein 15	0.053	Mouse
Tgfb1	transforming growth factor, beta 1	0.049
Crh	corticotropin releasing hormone	0.048	Rat
Ern2	endoplasmic reticulum (ER) to nucleus signalling 2	0.047
Kiss1	KiSS-1 metastasis-suppressor	0.046
Nos2	nitric oxide synthase 2, inducible	0.045
Thra	thyroid hormone receptor alpha	0.045
Csf1	colony stimulating factor 1 (macrophage)	0.044
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.044
Igf1	insulin-like growth factor 1	0.043
Bglap	bone gamma carboxyglutamate protein	0.041
Tgfbr3	transforming growth factor, beta receptor III	0.041
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.040
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.040
Kl	klotho	0.039
Gm5506	predicted gene 5506	0.039
Gpi1	glucose phosphate isomerase 1	0.037
Fbn1	fibrillin 1	0.036
Pten	phosphatase and tensin homolog	0.034
Mup4	major urinary protein 4	0.034	Mouse
Svs5	seminal vesicle secretory protein 5	0.034
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.034
Gapdh	glyceraldehyde-3-phosphate dehydrogenase	0.034
Wwox	WW domain-containing oxidoreductase	0.031
Drd2	dopamine receptor D2	0.030	Rat
Adipoq	adiponectin, C1Q and collagen domain containing	0.030
Ldha	lactate dehydrogenase A	0.030
Pdx1	pancreatic and duodenal homeobox 1	0.030
Kiss1r	KISS1 receptor	0.029
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.028
Sstr3	somatostatin receptor 3	0.028
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.028	Mouse
Cyp11b1	cytochrome P450, family 11, subfamily b, polypeptide 1	0.028
Apoe	apolipoprotein E	0.027
Cd70	CD70 antigen	0.027
Tpi1	triosephosphate isomerase 1	0.027
Adrb3	adrenergic receptor, beta 3	0.026
Pim3	proviral integration site 3	0.025
Cyp7a1	cytochrome P450, family 7, subfamily a, polypeptide 1	0.025
Inha	inhibin alpha	0.025
Prkg1	protein kinase, cGMP-dependent, type I	0.024
Atp7a	ATPase, Cu++ transporting, alpha polypeptide	0.024
Plin1	perilipin 1	0.023
Ckm	creatine kinase, muscle	0.023
Lipe	lipase, hormone sensitive	0.023
Acvr1	activin A receptor, type 1	0.023	Mouse
H2-DMa	histocompatibility 2, class II, locus DMa	0.022
Scd1	stearoyl-Coenzyme A desaturase 1	0.022
Eng	endoglin	0.021
Apc	adenomatosis polyposis coli	0.021
Srf	serum response factor	0.021
Grxcr1	glutaredoxin, cysteine rich 1	0.020
Nr1h4	nuclear receptor subfamily 1, group H, member 4	0.020	Mouse
Skil	SKI-like	0.020
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.020
Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	0.020
Zbtb7a	zinc finger and BTB domain containing 7a	0.020
Sik3	SIK family kinase 3	0.020
Pim2	proviral integration site 2	0.019	Mouse
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.019
Ucp3	uncoupling protein 3 (mitochondrial, proton carrier)	0.019
Socs1	suppressor of cytokine signaling 1	0.019
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.019
Azgp1	alpha-2-glycoprotein 1, zinc	0.018
Utf1	undifferentiated embryonic cell transcription factor 1	0.018
Ryr2	ryanodine receptor 2, cardiac	0.018
Abcc6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	0.018
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.018
Ifnb1	interferon beta 1, fibroblast	0.017
Ang2	angiogenin, ribonuclease A family, member 2	0.017
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.017
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.016
Vegfa	vascular endothelial growth factor A	0.016
Pcsk4	proprotein convertase subtilisin/kexin type 4	0.016
En1	engrailed 1	0.015
Sry	sex determining region of Chr Y	0.015
Shc1	src homology 2 domain-containing transforming protein C1	0.015
Vav1	vav 1 oncogene	0.015
Pde8b	phosphodiesterase 8B	0.014	Rat
Nf1	neurofibromatosis 1	0.014
Hand2	heart and neural crest derivatives expressed transcript 2	0.014
Otc	ornithine transcarbamylase	0.014
Pgam1	phosphoglycerate mutase 1	0.014
Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2	0.014
Accn5	amiloride-sensitive cation channel 5, intestinal	0.014
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.014
Chst8	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8	0.014
Tshr	thyroid stimulating hormone receptor	0.013
Jag1	jagged 1	0.013
Fasn	fatty acid synthase	0.013
Pfkl	phosphofructokinase, liver, B-type	0.013
Stat5a	signal transducer and activator of transcription 5A	0.013
Agrp	agouti related protein	0.013
U46068	cDNA sequence U46068	0.013
Prodh2	proline dehydrogenase (oxidase) 2	0.013
Homer1	homer homolog 1 (Drosophila)	0.013
Scn10a	sodium channel, voltage-gated, type X, alpha	0.013
Cacna1b	calcium channel, voltage-dependent, N type, alpha 1B subunit	0.013
Apoa4	apolipoprotein A-IV	0.012
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.012
Ncoa3	nuclear receptor coactivator 3	0.012
Agtr2	angiotensin II receptor, type 2	0.012
Mesp1	mesoderm posterior 1	0.012
Drd1a	dopamine receptor D1A	0.012
Ece1	endothelin converting enzyme 1	0.012
Klk1b4	kallikrein 1-related pepidase b4	0.012
Smad3	MAD homolog 3 (Drosophila)	0.012
Vdr	vitamin D receptor	0.012	Mouse
Klk1b26	kallikrein 1-related petidase b26	0.012
1810021B22Rik	RIKEN cDNA 1810021B22 gene	0.011
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.011
Tnp2	transition protein 2	0.011
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.011
Gjb1	gap junction protein, beta 1	0.011
Klk1b8	kallikrein 1-related peptidase b8	0.011
Npy1r	neuropeptide Y receptor Y1	0.011
Bglap2	bone gamma-carboxyglutamate protein 2	0.011
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.011
Nsf	N-ethylmaleimide sensitive fusion protein	0.011
Htr4	5 hydroxytryptamine (serotonin) receptor 4	0.011
Rab27a	RAB27A, member RAS oncogene family	0.011
Nodal	nodal	0.011
Mgp	matrix Gla protein	0.010
Cidec	cell death-inducing DFFA-like effector c	0.010