Mus musculus

71 known processes

Ric8

resistance to inhibitors of cholinesterase 8 homolog (C. elegans)

(Aliases: RIC-8,AI114950,Ric8a)

Ric8 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of interleukin 2 secretion GO:1900040 6 0.999
interleukin 2 secretion GO:0070970 7 0.980
positive regulation of interferon gamma secretion GO:1902715 3 0.905
regulation of engulfment of apoptotic cell GO:1901074 2 0.895
positive regulation of non canonical wnt signaling pathway GO:2000052 6 0.811
negative regulation of phagocytosis GO:0050765 4 0.744
substrate dependent cell migration cell extension GO:0006930 4 0.565
compound eye development GO:0048749 1 0.554
negative regulation of cell aging GO:0090344 5 0.498
negative regulation of apoptotic cell clearance GO:2000426 1 0.444
regulation of phospholipase c activity GO:1900274 3 0.416
positive regulation of wnt signaling pathway planar cell polarity pathway GO:2000096 5 0.332
positive regulation of protein export from nucleus GO:0046827 4 0.325
b 1 b cell homeostasis GO:0001922 4 0.321
engulfment of apoptotic cell GO:0043652 3 0.320
dendritic spine maintenance GO:0097062 4 0.307
negative regulation of endothelial cell apoptotic process GO:2000352 7 0.298
defense response to other organism GO:0098542 197 0.293
regulation of rho protein signal transduction GO:0035023 71 0.292
regulation of cellular amine metabolic process GO:0033238 20 0.282
negative regulation of phospholipase activity GO:0010519 4 0.273
small gtpase mediated signal transduction GO:0007264 97 0.266
regulation of interferon gamma secretion GO:1902713 3 0.263
defense response to fungus GO:0050832 12 0.263
ras protein signal transduction GO:0007265 77 0.257
establishment of planar polarity GO:0001736 28 0.254
morphogenesis of a polarized epithelium GO:0001738 37 0.251
actin filament branching GO:0090135 1 0.246
immature b cell differentiation GO:0002327 10 0.242
sequestering of calcium ion GO:0051208 18 0.238
negative regulation of rho protein signal transduction GO:0035024 7 0.223
cell adhesion GO:0007155 329 0.222
non canonical wnt signaling pathway GO:0035567 33 0.221
leukocyte homeostasis GO:0001776 79 0.210
visual behavior GO:0007632 45 0.208
b cell proliferation involved in immune response GO:0002322 5 0.206
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.204
positive regulation of nervous system development GO:0051962 221 0.203
establishment of tissue polarity GO:0007164 28 0.203
membrane organization GO:0061024 245 0.200
actin cytoskeleton organization GO:0030036 220 0.200
cerebellum development GO:0021549 77 0.200
rho protein signal transduction GO:0007266 32 0.200
negative regulation of ligase activity GO:0051352 3 0.198
negative regulation of phosphorus metabolic process GO:0010563 184 0.195
leukocyte activation involved in immune response GO:0002366 126 0.191
protein modification by small protein conjugation or removal GO:0070647 207 0.191
activation of immune response GO:0002253 138 0.190
spleen development GO:0048536 39 0.189
dendritic spine organization GO:0097061 26 0.188
substrate dependent cell migration GO:0006929 18 0.185
platelet derived growth factor receptor signaling pathway GO:0048008 32 0.184
sequestering of metal ion GO:0051238 19 0.184
negative regulation of ras protein signal transduction GO:0046580 18 0.181
lymphocyte proliferation GO:0046651 164 0.174
positive regulation of cell development GO:0010720 237 0.174
regulation of cellular amino acid metabolic process GO:0006521 5 0.173
spermatogenesis GO:0007283 284 0.171
regulation of cellular senescence GO:2000772 6 0.171
positive regulation of cytokine production GO:0001819 174 0.170
developmental growth involved in morphogenesis GO:0060560 138 0.170
regulation of interferon gamma production GO:0032649 57 0.168
regulation of establishment of planar polarity GO:0090175 28 0.166
regulation of cellular response to stress GO:0080135 159 0.159
b cell proliferation GO:0042100 53 0.158
negative regulation of cellular senescence GO:2000773 3 0.152
amine metabolic process GO:0009308 45 0.152
regulation of endothelial cell apoptotic process GO:2000351 9 0.150
negative regulation of homeostatic process GO:0032845 71 0.149
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.148
peptidyl tyrosine phosphorylation GO:0018108 143 0.145
cellular amine metabolic process GO:0044106 44 0.145
negative regulation of phosphate metabolic process GO:0045936 184 0.138
regulation of cellular ketone metabolic process GO:0010565 66 0.138
cellular ketone metabolic process GO:0042180 84 0.137
regulation of cell migration GO:0030334 219 0.136
immune effector process GO:0002252 321 0.136
positive regulation of mapk cascade GO:0043410 170 0.133
single organismal cell cell adhesion GO:0016337 131 0.132
cell type specific apoptotic process GO:0097285 268 0.131
metencephalon development GO:0022037 89 0.131
developmental maturation GO:0021700 193 0.131
protein ubiquitination GO:0016567 171 0.130
regulation of secretion by cell GO:1903530 249 0.128
positive regulation of secretion by cell GO:1903532 114 0.127
positive regulation of protein modification process GO:0031401 299 0.124
lymphocyte homeostasis GO:0002260 64 0.124
regulation of cell shape GO:0008360 39 0.124
cellular senescence GO:0090398 11 0.124
b cell activation involved in immune response GO:0002312 50 0.121
regulation of synaptic growth at neuromuscular junction GO:0008582 4 0.121
regulation of phagocytosis engulfment GO:0060099 5 0.120
t cell proliferation GO:0042098 120 0.118
peptidyl tyrosine modification GO:0018212 145 0.118
positive regulation of neuron differentiation GO:0045666 141 0.117
protein modification by small protein conjugation GO:0032446 187 0.116
negative regulation of erk1 and erk2 cascade GO:0070373 21 0.115
neuron death GO:0070997 154 0.115
positive regulation of homeostatic process GO:0032846 64 0.113
extracellular matrix organization GO:0030198 147 0.112
regulation of cytokine production GO:0001817 266 0.112
regulation of ras protein signal transduction GO:0046578 114 0.112
alpha beta t cell activation GO:0046631 91 0.111
visual learning GO:0008542 44 0.111
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.111
actin filament bundle assembly GO:0051017 40 0.111
cellular metal ion homeostasis GO:0006875 151 0.109
leukocyte differentiation GO:0002521 342 0.109
regulation of homeostatic process GO:0032844 182 0.108
regulation of calcium ion transport into cytosol GO:0010522 31 0.108
alpha beta t cell differentiation GO:0046632 69 0.108
regulation of ion homeostasis GO:2000021 64 0.106
cell aging GO:0007569 35 0.105
neuromuscular process controlling balance GO:0050885 59 0.105
regulation of interleukin 2 production GO:0032663 28 0.104
leukocyte proliferation GO:0070661 172 0.103
cell activation involved in immune response GO:0002263 126 0.102
interferon gamma production GO:0032609 67 0.102
cellular response to biotic stimulus GO:0071216 92 0.099
positive regulation of cell projection organization GO:0031346 95 0.099
cellular response to molecule of bacterial origin GO:0071219 83 0.096
cytokine production GO:0001816 319 0.095
planar cell polarity pathway involved in axis elongation GO:0003402 4 0.095
positive regulation of cytokine secretion GO:0050715 41 0.095
mapk cascade GO:0000165 281 0.095
cytosolic calcium ion transport GO:0060401 48 0.095
negative regulation of molecular function GO:0044092 258 0.095
posttranscriptional regulation of gene expression GO:0010608 155 0.094
positive regulation of secretion GO:0051047 130 0.093
calcium ion transport into cytosol GO:0060402 48 0.093
positive regulation of calcium ion transport GO:0051928 27 0.092
negative regulation of cell cycle GO:0045786 123 0.092
calcium ion homeostasis GO:0055074 127 0.092
b cell activation GO:0042113 161 0.092
hindbrain development GO:0030902 128 0.091
cell maturation GO:0048469 127 0.088
b cell differentiation GO:0030183 78 0.088
b cell receptor signaling pathway GO:0050853 20 0.088
cation transport GO:0006812 399 0.088
lymphocyte activation involved in immune response GO:0002285 93 0.088
cellular ion homeostasis GO:0006873 165 0.088
regulation of cell cycle GO:0051726 281 0.087
positive regulation of protein phosphorylation GO:0001934 242 0.087
divalent inorganic cation transport GO:0072511 178 0.087
negative regulation of synapse assembly GO:0051964 3 0.086
cellular chemical homeostasis GO:0055082 215 0.086
negative regulation of nervous system development GO:0051961 156 0.085
regulation of secretion GO:0051046 274 0.085
regulation of cell motility GO:2000145 236 0.084
intracellular protein transport GO:0006886 204 0.084
calcium ion transport GO:0006816 159 0.084
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.084
metal ion homeostasis GO:0055065 189 0.084
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 194 0.083
regulation of neuron projection development GO:0010975 169 0.083
developmental cell growth GO:0048588 84 0.083
defense response to bacterium GO:0042742 119 0.082
nucleobase containing small molecule metabolic process GO:0055086 352 0.082
Worm
negative regulation of phosphorylation GO:0042326 166 0.082
hindbrain morphogenesis GO:0021575 46 0.082
divalent metal ion transport GO:0070838 172 0.082
cell recognition GO:0008037 83 0.081
regulation of transferase activity GO:0051338 263 0.081
negative regulation of cellular protein metabolic process GO:0032269 247 0.081
interleukin 2 production GO:0032623 33 0.081
response to lipopolysaccharide GO:0032496 128 0.080
regulation of mapk cascade GO:0043408 248 0.080
regulation of cytoskeleton organization GO:0051493 122 0.079
regulation of actin cytoskeleton organization GO:0032956 84 0.078
response to molecule of bacterial origin GO:0002237 143 0.078
learning GO:0007612 98 0.078
positive regulation of cellular amine metabolic process GO:0033240 5 0.078
positive regulation of protein transport GO:0051222 93 0.076
regulation of cell adhesion GO:0030155 154 0.076
glial cell differentiation GO:0010001 131 0.076
immune response activating signal transduction GO:0002757 116 0.075
positive regulation of interferon gamma production GO:0032729 39 0.074
divalent inorganic cation homeostasis GO:0072507 138 0.074
gliogenesis GO:0042063 141 0.074
regulation of neuron death GO:1901214 134 0.074
endothelial cell apoptotic process GO:0072577 9 0.074
cytokine secretion GO:0050663 72 0.073
regulation of actin filament based process GO:0032970 99 0.073
actin filament organization GO:0007015 113 0.072
regulation of protein transport GO:0051223 163 0.072
negative regulation of ubiquitin protein transferase activity GO:0051444 3 0.072
response to radiation GO:0009314 165 0.071
cell growth GO:0016049 130 0.071
regulation of lipase activity GO:0060191 15 0.070
positive regulation of calcium ion transport into cytosol GO:0010524 9 0.070
axis elongation GO:0003401 30 0.069
peptidyl amino acid modification GO:0018193 336 0.069
cell substrate adhesion GO:0031589 130 0.069
cognition GO:0050890 149 0.068
cellular calcium ion homeostasis GO:0006874 119 0.068
lymphocyte differentiation GO:0030098 242 0.068
axonogenesis GO:0007409 274 0.068
positive regulation of interleukin 2 production GO:0032743 19 0.068
regulation of protein binding GO:0043393 60 0.068
cerebellum morphogenesis GO:0021587 42 0.067
protein secretion GO:0009306 111 0.067
positive regulation of ion transport GO:0043270 65 0.067
cytosolic calcium ion homeostasis GO:0051480 70 0.067
positive regulation of neuron projection development GO:0010976 79 0.066
regulation of phagocytosis GO:0050764 33 0.066
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.066
neuromuscular process GO:0050905 99 0.065
response to light stimulus GO:0009416 135 0.064
signal transduction by p53 class mediator GO:0072331 51 0.064
nucleotide catabolic process GO:0009166 217 0.064
Worm
regulation of intracellular transport GO:0032386 159 0.063
glycosyl compound metabolic process GO:1901657 246 0.063
Worm
regulation of ion transport GO:0043269 215 0.063
positive regulation of protein secretion GO:0050714 52 0.063
cellular divalent inorganic cation homeostasis GO:0072503 127 0.062
regulation of organ morphogenesis GO:2000027 144 0.062
positive regulation of binding GO:0051099 49 0.061
positive regulation of erk1 and erk2 cascade GO:0070374 47 0.061
thymus development GO:0048538 41 0.061
single organism cell adhesion GO:0098602 156 0.061
regulation of cell aging GO:0090342 9 0.061
cellular homeostasis GO:0019725 240 0.061
maintenance of location GO:0051235 89 0.061
cytoplasmic transport GO:0016482 234 0.060
antigen receptor mediated signaling pathway GO:0050851 64 0.060
epidermal growth factor receptor signaling pathway GO:0007173 28 0.060
regulation of calcium ion transport GO:0051924 69 0.060
regulation of cytoplasmic transport GO:1903649 112 0.059
epithelial cell morphogenesis GO:0003382 41 0.059
homeostasis of number of cells GO:0048872 210 0.059
positive regulation of neuron death GO:1901216 28 0.059
substrate adhesion dependent cell spreading GO:0034446 30 0.059
release of sequestered calcium ion into cytosol GO:0051209 42 0.058
mitotic cell cycle GO:0000278 195 0.057
Worm
regulation of protein serine threonine kinase activity GO:0071900 157 0.057
positive regulation of apoptotic process GO:0043065 217 0.057
regulation of endocytosis GO:0030100 69 0.056
protein export from nucleus GO:0006611 20 0.056
positive regulation of phospholipase c activity GO:0010863 2 0.056
regulation of osteoblast proliferation GO:0033688 15 0.056
phagocytosis GO:0006909 66 0.056
membrane invagination GO:0010324 17 0.055
t cell activation GO:0042110 289 0.055
bergmann glial cell differentiation GO:0060020 6 0.055
positive regulation of cytoplasmic transport GO:1903651 40 0.054
muscle cell differentiation GO:0042692 261 0.054
regulation of erk1 and erk2 cascade GO:0070372 71 0.054
cell cycle checkpoint GO:0000075 47 0.054
regulation of organelle organization GO:0033043 289 0.054
erk1 and erk2 cascade GO:0070371 77 0.054
b cell homeostasis GO:0001782 34 0.053
wnt signaling pathway GO:0016055 188 0.053
regulation of wnt signaling pathway GO:0030111 123 0.053
negative regulation of hydrolase activity GO:0051346 71 0.052
regulation of cell projection organization GO:0031344 206 0.052
purine ribonucleotide metabolic process GO:0009150 290 0.052
Worm
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.051
neuron maturation GO:0042551 29 0.051
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.051
regulation of protein localization GO:0032880 231 0.050
negative regulation of protein metabolic process GO:0051248 282 0.050
negative regulation of cell migration GO:0030336 59 0.050
ribonucleotide metabolic process GO:0009259 291 0.050
Worm
regulation of kinase activity GO:0043549 249 0.050
positive regulation of intracellular protein transport GO:0090316 42 0.050
aromatic compound catabolic process GO:0019439 286 0.049
Worm
male gamete generation GO:0048232 285 0.049
regulation of metal ion transport GO:0010959 106 0.049
regulation of oxidoreductase activity GO:0051341 15 0.048
nuclear export GO:0051168 34 0.048
camera type eye development GO:0043010 266 0.047
cellular response to growth factor stimulus GO:0071363 197 0.047
regulation of mitotic cell cycle GO:0007346 126 0.047
purine ribonucleoside triphosphate metabolic process GO:0009205 220 0.047
Worm
regulation of cell activation GO:0050865 289 0.046
regulation of protein export from nucleus GO:0046825 11 0.046
positive regulation of intracellular transport GO:0032388 70 0.046
neuron migration GO:0001764 122 0.046
regulation of vesicle mediated transport GO:0060627 139 0.046
negative regulation of cell motility GO:2000146 61 0.046
positive regulation of cell death GO:0010942 224 0.045
positive regulation of programmed cell death GO:0043068 218 0.045
endomembrane system organization GO:0010256 147 0.045
regulation of hydrolase activity GO:0051336 246 0.045
Worm
negative regulation of mapk cascade GO:0043409 65 0.045
epithelial cell development GO:0002064 159 0.044
regulation of cellular component biogenesis GO:0044087 181 0.044
regulation of protein kinase activity GO:0045859 232 0.044
chemotaxis GO:0006935 247 0.044
nucleoside phosphate metabolic process GO:0006753 338 0.043
Worm
negative regulation of mitotic cell cycle GO:0045930 58 0.043
positive regulation of cell cycle GO:0045787 92 0.042
negative regulation of bmp signaling pathway GO:0030514 35 0.042
dna integrity checkpoint GO:0031570 28 0.042
bmp signaling pathway GO:0030509 93 0.042
positive regulation of wnt signaling pathway GO:0030177 45 0.042
astrocyte differentiation GO:0048708 43 0.042
negative regulation of protein modification process GO:0031400 163 0.042
dendrite development GO:0016358 115 0.041
gtp catabolic process GO:0006184 143 0.041
Worm
g protein coupled receptor signaling pathway GO:0007186 243 0.041
cation homeostasis GO:0055080 212 0.041
negative regulation of protein phosphorylation GO:0001933 126 0.041
learning or memory GO:0007611 148 0.041
cellular response to lipopolysaccharide GO:0071222 77 0.040
regulation of cytokine secretion GO:0050707 61 0.040
erbb signaling pathway GO:0038127 32 0.040
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.040
organonitrogen compound biosynthetic process GO:1901566 192 0.040
defense response to gram negative bacterium GO:0050829 28 0.040
regulation of response to dna damage stimulus GO:2001020 34 0.039
macromolecule catabolic process GO:0009057 281 0.039
regulation of intracellular protein transport GO:0033157 82 0.039
regulation of protein secretion GO:0050708 82 0.039
extracellular structure organization GO:0043062 148 0.039
purine nucleotide metabolic process GO:0006163 302 0.039
Worm
response to ionizing radiation GO:0010212 42 0.039
nucleoside triphosphate catabolic process GO:0009143 205 0.038
Worm
nucleoside triphosphate metabolic process GO:0009141 230 0.037
Worm
endocytosis GO:0006897 168 0.037
regulation of nucleocytoplasmic transport GO:0046822 73 0.037
purine containing compound metabolic process GO:0072521 311 0.037
Worm
neuron projection guidance GO:0097485 141 0.036
regulation of protein stability GO:0031647 52 0.036
nucleotide metabolic process GO:0009117 332 0.036
Worm
regulation of phospholipase activity GO:0010517 9 0.036
negative regulation of cell adhesion GO:0007162 45 0.036
cellular response to lipid GO:0071396 145 0.036
regulation of bmp signaling pathway GO:0030510 60 0.035
cellular component maintenance GO:0043954 11 0.035
gland development GO:0048732 330 0.034
dna metabolic process GO:0006259 303 0.034
negative regulation of cellular component organization GO:0051129 194 0.034
response to oxidative stress GO:0006979 123 0.034
regulation of binding GO:0051098 111 0.034
organic cyclic compound catabolic process GO:1901361 295 0.033
Worm
dna damage checkpoint GO:0000077 26 0.033
ribose phosphate metabolic process GO:0019693 291 0.033
Worm
i kappab kinase nf kappab signaling GO:0007249 85 0.033
regulation of cellular catabolic process GO:0031329 242 0.033
Worm
nuclear transport GO:0051169 139 0.032
negative regulation of response to dna damage stimulus GO:2001021 10 0.032
axon guidance GO:0007411 141 0.032
negative regulation of intracellular signal transduction GO:1902532 167 0.032
Worm
regulation of protein modification by small protein conjugation or removal GO:1903320 57 0.031
glycosyl compound catabolic process GO:1901658 206 0.031
Worm
regulation of establishment of protein localization GO:0070201 181 0.031
negative regulation of transferase activity GO:0051348 85 0.031
regulation of lymphocyte activation GO:0051249 240 0.031
negative regulation of lipase activity GO:0060192 7 0.030
regulation of purine nucleotide metabolic process GO:1900542 169 0.030
Worm
positive regulation of hydrolase activity GO:0051345 148 0.030
Worm
retrograde transport endosome to golgi GO:0042147 2 0.030
carbohydrate derivative catabolic process GO:1901136 231 0.030
Worm
reactive nitrogen species metabolic process GO:2001057 0 0.029
negative regulation of dna damage response signal transduction by p53 class mediator GO:0043518 5 0.029
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 10 0.029
negative regulation of protein modification by small protein conjugation or removal GO:1903321 20 0.029
positive regulation of protein kinase activity GO:0045860 144 0.029
associative learning GO:0008306 61 0.028
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.028
myosin filament organization GO:0031033 3 0.028
organophosphate catabolic process GO:0046434 232 0.028
Worm
regulation of protein ubiquitination GO:0031396 52 0.028
positive regulation of phospholipase activity GO:0010518 3 0.027
purine nucleoside metabolic process GO:0042278 241 0.027
Worm
negative regulation of kinase activity GO:0033673 81 0.027
exploration behavior GO:0035640 21 0.027
regulation of nucleotide metabolic process GO:0006140 169 0.027
Worm
negative regulation of cellular amine metabolic process GO:0033239 1 0.027
purine containing compound catabolic process GO:0072523 213 0.027
Worm
purine nucleoside triphosphate metabolic process GO:0009144 226 0.026
Worm
ribonucleoside metabolic process GO:0009119 245 0.026
Worm
regulation of extracellular matrix organization GO:1903053 11 0.026
ribonucleotide catabolic process GO:0009261 208 0.026
Worm
negative regulation of growth GO:0045926 99 0.025
anatomical structure homeostasis GO:0060249 145 0.025
ribonucleoside catabolic process GO:0042454 206 0.025
Worm
chromatin modification GO:0016568 187 0.025
ribonucleoside triphosphate catabolic process GO:0009203 199 0.025
Worm
purine nucleoside catabolic process GO:0006152 205 0.025
Worm
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.024
negative regulation of protein ubiquitination GO:0031397 19 0.024
nucleoside phosphate catabolic process GO:1901292 222 0.024
Worm
mitochondrion organization GO:0007005 134 0.024
negative regulation of protein serine threonine kinase activity GO:0071901 49 0.024
nitrogen compound transport GO:0071705 271 0.023
guanosine containing compound catabolic process GO:1901069 144 0.023
Worm
response to growth factor GO:0070848 198 0.023
t cell differentiation GO:0030217 174 0.023
protein catabolic process GO:0030163 221 0.023
nucleoside metabolic process GO:0009116 246 0.022
Worm
neuron recognition GO:0008038 25 0.022
nucleocytoplasmic transport GO:0006913 139 0.022
osteoblast proliferation GO:0033687 18 0.022
cellular response to dna damage stimulus GO:0006974 207 0.022
interferon gamma secretion GO:0072643 7 0.022
positive regulation of osteoblast proliferation GO:0033690 9 0.022
gtp metabolic process GO:0046039 144 0.022
Worm
regulation of reactive oxygen species metabolic process GO:2000377 40 0.021
positive regulation of nucleocytoplasmic transport GO:0046824 30 0.021
nucleoside catabolic process GO:0009164 206 0.021
Worm
positive regulation of nucleotide metabolic process GO:0045981 114 0.021
Worm
regulation of ubiquitin protein transferase activity GO:0051438 7 0.020
purine ribonucleoside catabolic process GO:0046130 205 0.020
Worm
positive regulation of protein binding GO:0032092 29 0.020
cellular nitrogen compound catabolic process GO:0044270 280 0.020
Worm
response to acid chemical GO:0001101 111 0.020
cellular macromolecule catabolic process GO:0044265 206 0.020
morphogenesis of embryonic epithelium GO:0016331 159 0.020
regulation of inflammatory response GO:0050727 147 0.020
oxidation reduction process GO:0055114 342 0.020
negative regulation of endocytosis GO:0045806 12 0.020
synapse assembly GO:0007416 56 0.020
heterocycle catabolic process GO:0046700 280 0.020
Worm
purine nucleotide catabolic process GO:0006195 211 0.019
Worm
ribonucleoside triphosphate metabolic process GO:0009199 220 0.019
Worm
digestive tract development GO:0048565 190 0.018
organic hydroxy compound metabolic process GO:1901615 203 0.018
dna damage response signal transduction by p53 class mediator GO:0030330 19 0.018
synapse organization GO:0050808 125 0.018
cellular protein catabolic process GO:0044257 155 0.018
sensory organ morphogenesis GO:0090596 242 0.018
respiratory system development GO:0060541 190 0.018
regulation of synapse assembly GO:0051963 29 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 0 0.018
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.018
regulation of map kinase activity GO:0043405 120 0.017
cellular response to cytokine stimulus GO:0071345 189 0.017
purine ribonucleoside metabolic process GO:0046128 241 0.017
Worm
organelle localization GO:0051640 179 0.017
embryonic epithelial tube formation GO:0001838 130 0.017
cellular amino acid metabolic process GO:0006520 103 0.017
striated muscle myosin thick filament assembly GO:0071688 1 0.017
neuron projection extension GO:1990138 64 0.017
small molecule biosynthetic process GO:0044283 132 0.017
organonitrogen compound catabolic process GO:1901565 264 0.017
Worm
regionalization GO:0003002 337 0.017
stress activated protein kinase signaling cascade GO:0031098 81 0.017
positive regulation of lymphocyte activation GO:0051251 140 0.017
myosin filament assembly GO:0031034 2 0.017
mitotic cell cycle process GO:1903047 159 0.017
Worm
purine ribonucleotide catabolic process GO:0009154 208 0.017
Worm
regulation of adaptive immune response GO:0002819 90 0.017
reactive oxygen species biosynthetic process GO:1903409 8 0.016
regulation of lymphocyte proliferation GO:0050670 117 0.016
lung development GO:0030324 164 0.016
regulation of leukocyte proliferation GO:0070663 121 0.016
regulation of protein catabolic process GO:0042176 108 0.016
response to organonitrogen compound GO:0010243 246 0.016
leukocyte mediated immunity GO:0002443 174 0.016
positive regulation of cell activation GO:0050867 158 0.016
neuron remodeling GO:0016322 7 0.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.016
multicellular organismal homeostasis GO:0048871 164 0.016
negative regulation of cell proliferation GO:0008285 296 0.016
apoptotic cell clearance GO:0043277 17 0.016
lipid biosynthetic process GO:0008610 179 0.016
dephosphorylation GO:0016311 129 0.016
regulation of neuron differentiation GO:0045664 281 0.016
carbohydrate derivative biosynthetic process GO:1901137 183 0.016
regulation of reactive oxygen species biosynthetic process GO:1903426 2 0.016
purine nucleoside triphosphate catabolic process GO:0009146 203 0.015
Worm
establishment of protein localization to organelle GO:0072594 118 0.015
positive regulation of mitotic cell cycle GO:0045931 41 0.015
protein localization to organelle GO:0033365 185 0.015
viral gene expression GO:0019080 3 0.015
cation transmembrane transport GO:0098655 266 0.015
positive regulation of kinase activity GO:0033674 155 0.015
positive regulation of nucleoside metabolic process GO:0045979 91 0.015
Worm
actomyosin structure organization GO:0031032 56 0.015
neuron apoptotic process GO:0051402 142 0.015
negative regulation of inflammatory response GO:0050728 61 0.015
negative regulation of cytokine production GO:0001818 84 0.015
tube closure GO:0060606 91 0.015
neural tube development GO:0021915 160 0.015
response to insulin GO:0032868 100 0.015
positive regulation of immune effector process GO:0002699 107 0.015
cellular protein complex assembly GO:0043623 116 0.015
motor neuron axon guidance GO:0008045 26 0.014
regulation of leukocyte mediated immunity GO:0002703 104 0.014
tissue homeostasis GO:0001894 115 0.014
cellular lipid metabolic process GO:0044255 323 0.014
peptide secretion GO:0002790 114 0.014
tube formation GO:0035148 140 0.014
reactive oxygen species metabolic process GO:0072593 84 0.014
regulation of chromosome organization GO:0033044 83 0.014
regulation of cyclic nucleotide metabolic process GO:0030799 40 0.014
negative regulation of organelle organization GO:0010639 90 0.014
production of molecular mediator of immune response GO:0002440 103 0.014
innate immune response GO:0045087 157 0.014
regulation of production of molecular mediator of immune response GO:0002700 65 0.014
digestive tract morphogenesis GO:0048546 147 0.014
regulation of response to wounding GO:1903034 189 0.013
ossification GO:0001503 216 0.013

Ric8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.016