IMP
Process View
b 1 b cell homeostasis
The process of regulating the proliferation and elimination of B cells of the B-1 subset such that the total number of B-1 B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "b 1 b cell homeostasis"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Vhl | von Hippel-Lindau tumor suppressor | 0.760 | ||
| Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | 0.542 | ||
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.458 | ||
| Egln1 | EGL nine homolog 1 (C. elegans) | 0.415 | ||
| Ric8 | resistance to inhibitors of cholinesterase 8 homolog (C. elegans) | 0.321 | ||
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.314 | ||
| Pten | phosphatase and tensin homolog | 0.243 | ||
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.225 | ||
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.153 | ||
| Traf6 | TNF receptor-associated factor 6 | 0.122 | ||
| Lepr | leptin receptor | 0.103 | ||
| Map3k8 | mitogen-activated protein kinase kinase kinase 8 | 0.086 | ||
| Ripk1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.083 | ||
| Stat3 | signal transducer and activator of transcription 3 | 0.082 | ||
| Hdac7 | histone deacetylase 7 | 0.079 | ||
| Arnt | aryl hydrocarbon receptor nuclear translocator | 0.077 | ||
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.072 | ||
| Socs1 | suppressor of cytokine signaling 1 | 0.071 | ||
| Hbb-b1 | hemoglobin, beta adult major chain | 0.070 | ||
| Traf2 | TNF receptor-associated factor 2 | 0.059 | ||
| Arntl | aryl hydrocarbon receptor nuclear translocator-like | 0.057 | ||
| Braf | Braf transforming gene | 0.055 | ||
| Insr | insulin receptor | 0.054 | ||
| Dok1 | docking protein 1 | 0.054 | ||
| Jak2 | Janus kinase 2 | 0.043 | ||
| Fzd4 | frizzled homolog 4 (Drosophila) | 0.039 | ||
| Nfe2l2 | nuclear factor, erythroid derived 2, like 2 | 0.038 | ||
| Myl2 | myosin, light polypeptide 2, regulatory, cardiac, slow | 0.037 | ||
| Aff1 | AF4/FMR2 family, member 1 | 0.037 | ||
| Pdx1 | pancreatic and duodenal homeobox 1 | 0.036 | ||
| Gdnf | glial cell line derived neurotrophic factor | 0.035 | ||
| Skil | SKI-like | 0.035 | ||
| Hspg2 | perlecan (heparan sulfate proteoglycan 2) | 0.033 | ||
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.032 | ||
| Fgf8 | fibroblast growth factor 8 | 0.032 | ||
| Vegfa | vascular endothelial growth factor A | 0.032 | ||
| En1 | engrailed 1 | 0.032 | ||
| Otp | orthopedia homolog (Drosophila) | 0.032 | ||
| Adam17 | a disintegrin and metallopeptidase domain 17 | 0.030 | ||
| Sim2 | single-minded homolog 2 (Drosophila) | 0.028 | Mouse | |
| Sykb | spleen tyrosine kinase | 0.028 | ||
| Foxf1a | forkhead box F1a | 0.027 | ||
| Klf3 | Kruppel-like factor 3 (basic) | 0.026 | ||
| Arhgef2 | rho/rac guanine nucleotide exchange factor (GEF) 2 | 0.026 | ||
| Hoxd9 | homeobox D9 | 0.025 | ||
| Map3k7 | mitogen-activated protein kinase kinase kinase 7 | 0.025 | ||
| Tnfrsf11a | tumor necrosis factor receptor superfamily, member 11a | 0.025 | ||
| Wt1 | Wilms tumor 1 homolog | 0.024 | ||
| Blnk | B-cell linker | 0.024 | ||
| Pnpla2 | patatin-like phospholipase domain containing 2 | 0.024 | ||
| Eya4 | eyes absent 4 homolog (Drosophila) | 0.024 | ||
| Fas | Fas (TNF receptor superfamily member 6) | 0.024 | ||
| Fosl2 | fos-like antigen 2 | 0.023 | ||
| Kcnj12 | potassium inwardly-rectifying channel, subfamily J, member 12 | 0.023 | ||
| Ptpn14 | protein tyrosine phosphatase, non-receptor type 14 | 0.023 | ||
| Zfp36l2 | zinc finger protein 36, C3H type-like 2 | 0.023 | ||
| Zbtb7b | zinc finger and BTB domain containing 7B | 0.022 | ||
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.022 | ||
| Prkcd | protein kinase C, delta | 0.022 | ||
| Wnk2 | WNK lysine deficient protein kinase 2 | 0.022 | ||
| P4htm | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 0.022 | ||
| Clcnka | chloride channel Ka | 0.021 | ||
| Des | desmin | 0.021 | ||
| Hif1a | hypoxia inducible factor 1, alpha subunit | 0.021 | ||
| Tbx15 | T-box 15 | 0.020 | ||
| Tsga10 | testis specific 10 | 0.020 | ||
| Lmx1b | LIM homeobox transcription factor 1 beta | 0.020 | ||
| Abl1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.020 | ||
| Atp2a3 | ATPase, Ca++ transporting, ubiquitous | 0.019 | ||
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.019 | ||
| Sod3 | superoxide dismutase 3, extracellular | 0.019 | ||
| Epor | erythropoietin receptor | 0.019 | ||
| Mapk7 | mitogen-activated protein kinase 7 | 0.019 | ||
| E2f8 | E2F transcription factor 8 | 0.018 | ||
| Flt1 | FMS-like tyrosine kinase 1 | 0.018 | ||
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.018 | ||
| Sox17 | SRY-box containing gene 17 | 0.018 | ||
| Abl2 | v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene) | 0.018 | Mouse | |
| Cbl | Casitas B-lineage lymphoma | 0.018 | ||
| Foxo1 | forkhead box O1 | 0.018 | ||
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.018 | ||
| Sh3pxd2a | SH3 and PX domains 2A | 0.018 | ||
| Tmem116 | transmembrane protein 116 | 0.017 | ||
| Tnip1 | TNFAIP3 interacting protein 1 | 0.017 | ||
| Pgf | placental growth factor | 0.017 | ||
| Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.017 | ||
| Nrtn | neurturin | 0.016 | ||
| Tgfbr3 | transforming growth factor, beta receptor III | 0.016 | ||
| Ppard | peroxisome proliferator activator receptor delta | 0.016 | ||
| Ikzf1 | IKAROS family zinc finger 1 | 0.016 | ||
| Rel | reticuloendotheliosis oncogene | 0.016 | ||
| Mageb3 | melanoma antigen, family B, 3 | 0.016 | ||
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.016 | ||
| Slc23a2 | solute carrier family 23 (nucleobase transporters), member 2 | 0.015 | ||
| Adrb1 | adrenergic receptor, beta 1 | 0.015 | ||
| Hprt | hypoxanthine guanine phosphoribosyl transferase | 0.015 | ||
| Hoxa4 | homeobox A4 | 0.015 | ||
| Atn1 | atrophin 1 | 0.015 | ||
| Azin1 | antizyme inhibitor 1 | 0.015 | ||
| Nkx6-1 | NK6 homeobox 1 | 0.015 | ||
| Zfp358 | zinc finger protein 358 | 0.014 | ||
| Ptk2 | PTK2 protein tyrosine kinase 2 | 0.014 | ||
| Trp53 | transformation related protein 53 | 0.014 | ||
| P2ry2 | purinergic receptor P2Y, G-protein coupled 2 | 0.014 | ||
| Pla2g2c | phospholipase A2, group IIC | 0.014 | ||
| BC057022 | cDNA sequence BC057022 | 0.014 | ||
| Foxd2 | forkhead box D2 | 0.014 | ||
| Degs2 | degenerative spermatocyte homolog 2 (Drosophila), lipid desaturase | 0.014 | ||
| Sgpl1 | sphingosine phosphate lyase 1 | 0.013 | ||
| Ptger1 | prostaglandin E receptor 1 (subtype EP1) | 0.013 | ||
| Ncoa2 | nuclear receptor coactivator 2 | 0.013 | ||
| Igf1r | insulin-like growth factor I receptor | 0.013 | ||
| Tssk6 | testis-specific serine kinase 6 | 0.013 | ||
| Myd88 | myeloid differentiation primary response gene 88 | 0.013 | ||
| Dctn1 | dynactin 1 | 0.013 | ||
| Wnt9a | wingless-type MMTV integration site 9A | 0.013 | ||
| Actn3 | actinin alpha 3 | 0.013 | ||
| Ubtd1 | ubiquitin domain containing 1 | 0.013 | ||
| Tcf12 | transcription factor 12 | 0.013 | ||
| Sh3rf3 | SH3 domain containing ring finger 3 | 0.012 | ||
| Mknk2 | MAP kinase-interacting serine/threonine kinase 2 | 0.012 | ||
| Jak3 | Janus kinase 3 | 0.012 | ||
| Sav1 | salvador homolog 1 (Drosophila) | 0.012 | ||
| Fitm1 | fat storage-inducing transmembrane protein 1 | 0.012 | ||
| Smad4 | MAD homolog 4 (Drosophila) | 0.012 | ||
| Tgfbr1 | transforming growth factor, beta receptor I | 0.012 | ||
| Irs2 | insulin receptor substrate 2 | 0.012 | ||
| Itgb3 | integrin beta 3 | 0.012 | ||
| Zfand5 | zinc finger, AN1-type domain 5 | 0.012 | ||
| Snai1 | snail homolog 1 (Drosophila) | 0.012 | ||
| Pcsk7 | proprotein convertase subtilisin/kexin type 7 | 0.012 | ||
| Pim1 | proviral integration site 1 | 0.012 | ||
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.012 | ||
| Ccdc96 | coiled-coil domain containing 96 | 0.012 | ||
| Rxra | retinoid X receptor alpha | 0.011 | ||
| Galr1 | galanin receptor 1 | 0.011 | ||
| Wnt6 | wingless-related MMTV integration site 6 | 0.011 | ||
| Hipk3 | homeodomain interacting protein kinase 3 | 0.011 | ||
| Nrap | nebulin-related anchoring protein | 0.011 | ||
| Egfr | epidermal growth factor receptor | 0.011 | ||
| Tmem200b | transmembrane protein 200B | 0.011 | ||
| Cdon | cell adhesion molecule-related/down-regulated by oncogenes | 0.011 | ||
| Sorbs3 | sorbin and SH3 domain containing 3 | 0.011 | ||
| Ebf3 | early B-cell factor 3 | 0.011 | ||
| Asb10 | ankyrin repeat and SOCS box-containing 10 | 0.011 | ||
| Slc27a1 | solute carrier family 27 (fatty acid transporter), member 1 | 0.011 | ||
| Guca2b | guanylate cyclase activator 2b (retina) | 0.011 | ||
| Hoxa10 | homeobox A10 | 0.011 | ||
| Wasf1 | WASP family 1 | 0.011 | ||
| Vipr1 | vasoactive intestinal peptide receptor 1 | 0.011 | ||
| Numa1 | nuclear mitotic apparatus protein 1 | 0.011 | ||
| Ank1 | ankyrin 1, erythroid | 0.011 | ||
| Nfatc2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.011 | ||
| Smad3 | MAD homolog 3 (Drosophila) | 0.010 | ||
| Gck | glucokinase | 0.010 | ||
| Prap1 | proline-rich acidic protein 1 | 0.010 | ||
| Spry4 | sprouty homolog 4 (Drosophila) | 0.010 | ||
| Gtpbp2 | GTP binding protein 2 | 0.010 | ||
| Slc7a2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.010 | ||
| Tcfap2c | transcription factor AP-2, gamma | 0.010 | ||
| Ldb3 | LIM domain binding 3 | 0.010 | ||
| LOC100503441 | hypothetical protein LOC100503441 | 0.010 | ||
| Ihh | Indian hedgehog | 0.010 | ||
| Vav2 | vav 2 oncogene | 0.010 |