Mus musculus

0 known processes

Sit1

suppression inducing transmembrane adaptor 1

(Aliases: Sit)

Sit1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
interleukin 12 secretion GO:0072610 3 0.555
antigen receptor mediated signaling pathway GO:0050851 64 0.472
regulation of cell activation GO:0050865 289 0.412
Human
regulation of eosinophil degranulation GO:0043309 1 0.353
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.298
lymphocyte differentiation GO:0030098 242 0.297
adaptive immune response GO:0002250 155 0.285
regulation of cellular amine metabolic process GO:0033238 20 0.254
inflammatory response GO:0006954 244 0.253
blastocyst growth GO:0001832 23 0.243
positive regulation of t cell costimulation GO:2000525 2 0.241
ensheathment of neurons GO:0007272 76 0.239
cation transport GO:0006812 399 0.236
regulation of cellular ketone metabolic process GO:0010565 66 0.236
immune effector process GO:0002252 321 0.231
positive regulation of monocyte chemotaxis GO:0090026 2 0.231
cation homeostasis GO:0055080 212 0.218
immune response regulating cell surface receptor signaling pathway GO:0002768 80 0.215
helper t cell chemotaxis GO:0035704 1 0.209
leukocyte differentiation GO:0002521 342 0.197
multicellular organismal signaling GO:0035637 91 0.196
positive regulation of cellular amine metabolic process GO:0033240 5 0.188
regulation of membrane potential GO:0042391 192 0.177
immune complex clearance GO:0002434 2 0.176
leukocyte mediated immunity GO:0002443 174 0.174
regulation of protein kinase activity GO:0045859 232 0.165
regulation of cytokine production GO:0001817 266 0.160
action potential GO:0001508 78 0.153
myeloid cell activation involved in immune response GO:0002275 34 0.150
apoptotic signaling pathway GO:0097190 306 0.149
immune response regulating signaling pathway GO:0002764 125 0.147
gamma delta t cell lineage commitment GO:0002365 1 0.144
amine metabolic process GO:0009308 45 0.143
cytokine secretion GO:0050663 72 0.139
regulation of lymphocyte anergy GO:0002911 4 0.138
defense response to other organism GO:0098542 197 0.138
mature dendritic cell differentiation GO:0097029 3 0.134
t cell activation GO:0042110 289 0.133
Human
positive regulation of hematopoietic stem cell migration GO:2000473 1 0.130
cellular amine metabolic process GO:0044106 44 0.128
regulation of immunological synapse formation GO:2000520 2 0.123
regulation of interleukin 2 production GO:0032663 28 0.122
regulation of secretion by cell GO:1903530 249 0.120
t cell costimulation GO:0031295 14 0.117
endocytosis GO:0006897 168 0.117
regulation of kinase activity GO:0043549 249 0.117
positive regulation of cell activation GO:0050867 158 0.117
negative regulation of cell proliferation GO:0008285 296 0.117
metal ion homeostasis GO:0055065 189 0.116
regulation of transferase activity GO:0051338 263 0.115
cytokine production GO:0001816 319 0.114
g protein coupled receptor signaling pathway GO:0007186 243 0.114
cellular metal ion homeostasis GO:0006875 151 0.113
regulation of lymphocyte proliferation GO:0050670 117 0.111
cellular homeostasis GO:0019725 240 0.110
cellular amino acid metabolic process GO:0006520 103 0.110
immune response activating cell surface receptor signaling pathway GO:0002429 72 0.109
positive regulation of lymphocyte activation GO:0051251 140 0.108
leukocyte proliferation GO:0070661 172 0.108
cell adhesion GO:0007155 329 0.107
cell type specific apoptotic process GO:0097285 268 0.106
negative regulation of eosinophil degranulation GO:0043310 1 0.106
positive regulation of dendritic cell chemotaxis GO:2000510 1 0.105
lymphocyte proliferation GO:0046651 164 0.103
hematopoietic stem cell migration GO:0035701 1 0.102
neuronal action potential GO:0019228 54 0.102
immunoglobulin production GO:0002377 73 0.098
positive regulation of cell death GO:0010942 224 0.097
epithelial tube morphogenesis GO:0060562 303 0.096
positive regulation of monocyte extravasation GO:2000439 1 0.095
regulation of cellular amino acid metabolic process GO:0006521 5 0.094
regulation of t cell extravasation GO:2000407 3 0.092
cellular ketone metabolic process GO:0042180 84 0.090
germ cell development GO:0007281 185 0.089
regulation of map kinase activity GO:0043405 120 0.089
regulation of apoptotic signaling pathway GO:2001233 197 0.088
t cell differentiation in thymus GO:0033077 77 0.087
peptidyl amino acid modification GO:0018193 336 0.087
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 145 0.086
transmission of nerve impulse GO:0019226 76 0.086
cytokine biosynthetic process GO:0042089 68 0.085
adult behavior GO:0030534 135 0.084
eosinophil mediated immunity GO:0002447 1 0.084
regulation of system process GO:0044057 200 0.082
positive regulation of inflammatory response GO:0050729 47 0.080
leukocyte degranulation GO:0043299 27 0.078
synaptic transmission GO:0007268 329 0.077
myeloid leukocyte activation GO:0002274 83 0.077
protein processing GO:0016485 163 0.075
cd8 positive alpha beta t cell extravasation GO:0035697 3 0.075
negative regulation of immune effector process GO:0002698 55 0.075
response to molecule of bacterial origin GO:0002237 143 0.074
interleukin 8 secretion GO:0072606 3 0.074
regulation of inflammatory response GO:0050727 147 0.072
b cell activation GO:0042113 161 0.071
divalent inorganic cation homeostasis GO:0072507 138 0.071
mapk cascade GO:0000165 281 0.071
positive regulation of cell development GO:0010720 237 0.071
negative regulation of interleukin 8 production GO:0032717 1 0.071
regulation of secretion GO:0051046 274 0.069
sensory perception GO:0007600 245 0.069
positive regulation of t cell receptor signaling pathway GO:0050862 4 0.068
cellular calcium ion homeostasis GO:0006874 119 0.067
regulation of monocyte chemotaxis GO:0090025 3 0.067
divalent metal ion transport GO:0070838 172 0.066
regulation of t cell anergy GO:0002667 4 0.066
positive regulation of t cell extravasation GO:2000409 2 0.066
positive regulation of apoptotic process GO:0043065 217 0.066
interleukin 2 production GO:0032623 33 0.066
homeostasis of number of cells GO:0048872 210 0.065
positive regulation of t cell activation GO:0050870 101 0.065
olfactory learning GO:0008355 2 0.064
regulation of immune complex clearance by monocytes and macrophages GO:0090264 2 0.064
interleukin 8 production GO:0032637 4 0.064
regulation of dendritic cell chemotaxis GO:2000508 1 0.064
positive regulation of transferase activity GO:0051347 167 0.064
regulation of interleukin 8 production GO:0032677 3 0.063
negative regulation of apoptotic signaling pathway GO:2001234 104 0.063
positive regulation of cytokine biosynthetic process GO:0042108 40 0.062
fatty acid biosynthetic process GO:0006633 41 0.061
negative t cell selection GO:0043383 13 0.061
protein maturation GO:0051604 176 0.061
eosinophil activation GO:0043307 1 0.060
positive regulation of immunological synapse formation GO:2000522 1 0.060
response to bacterial lipoprotein GO:0032493 4 0.060
alpha beta t cell activation GO:0046631 91 0.060
nitrogen compound transport GO:0071705 271 0.059
positive regulation of protein modification process GO:0031401 299 0.059
regulation of adaptive immune response GO:0002819 90 0.058
regulation of leukocyte apoptotic process GO:2000106 56 0.058
response to lipopolysaccharide GO:0032496 128 0.057
positive regulation of protein phosphorylation GO:0001934 242 0.056
endomembrane system organization GO:0010256 147 0.055
axon ensheathment GO:0008366 76 0.055
regulation of t cell activation GO:0050863 170 0.055
Human
positive regulation of cd8 positive alpha beta t cell extravasation GO:2000451 2 0.055
calcium ion homeostasis GO:0055074 127 0.053
sequestering of calcium ion GO:0051208 18 0.053
negative thymic t cell selection GO:0045060 12 0.053
regulation of mapk cascade GO:0043408 248 0.053
myelination GO:0042552 74 0.053
muscle contraction GO:0006936 101 0.053
chemokine mediated signaling pathway GO:0070098 17 0.052
maintenance of location GO:0051235 89 0.052
activation of immune response GO:0002253 138 0.052
exocytosis GO:0006887 121 0.051
purine nucleotide metabolic process GO:0006163 302 0.051
production of molecular mediator of immune response GO:0002440 103 0.049
t helper 17 cell chemotaxis GO:0035705 1 0.049
regulation of phospholipase c activity GO:1900274 3 0.049
positive regulation of programmed cell death GO:0043068 218 0.049
regulation of lymphocyte apoptotic process GO:0070228 41 0.049
positive regulation of kinase activity GO:0033674 155 0.049
eosinophil activation involved in immune response GO:0002278 1 0.049
regulation of exocytosis GO:0017157 61 0.049
thymic t cell selection GO:0045061 22 0.049
regulation of t cell costimulation GO:2000523 2 0.049
leukocyte apoptotic process GO:0071887 71 0.049
protein secretion GO:0009306 111 0.048
eosinophil degranulation GO:0043308 1 0.048
regulation of monocyte extravasation GO:2000437 2 0.048
cellular divalent inorganic cation homeostasis GO:0072503 127 0.048
negative regulation of leukocyte apoptotic process GO:2000107 31 0.048
muscle tissue development GO:0060537 308 0.048
mature natural killer cell chemotaxis GO:0035782 1 0.048
response to acid chemical GO:0001101 111 0.048
lymphocyte costimulation GO:0031294 15 0.047
acute inflammatory response to antigenic stimulus GO:0002438 12 0.047
regulation of response to wounding GO:1903034 189 0.047
epithelial cell proliferation GO:0050673 174 0.047
nucleobase containing small molecule metabolic process GO:0055086 352 0.047
cellular modified amino acid metabolic process GO:0006575 63 0.047
cardiac muscle tissue development GO:0048738 130 0.046
cell fate commitment GO:0045165 210 0.046
cellular response to organonitrogen compound GO:0071417 145 0.045
cell chemotaxis GO:0060326 81 0.045
nucleotide metabolic process GO:0009117 332 0.045
cellular ion homeostasis GO:0006873 165 0.045
organonitrogen compound biosynthetic process GO:1901566 192 0.044
posttranscriptional regulation of gene expression GO:0010608 155 0.044
regulation of vesicle mediated transport GO:0060627 139 0.044
small molecule biosynthetic process GO:0044283 132 0.044
t cell extravasation GO:0072683 4 0.043
regulation of asymmetric cell division GO:0009786 4 0.043
negative regulation of immune system process GO:0002683 209 0.043
positive regulation of immune complex clearance by monocytes and macrophages GO:0090265 2 0.043
acute inflammatory response GO:0002526 41 0.043
regulation of interleukin 8 secretion GO:2000482 2 0.043
t cell differentiation GO:0030217 174 0.042
cell activation involved in immune response GO:0002263 126 0.042
organelle fission GO:0048285 170 0.042
monosaccharide metabolic process GO:0005996 106 0.042
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 45 0.042
response to peptide hormone GO:0043434 127 0.041
chemotaxis GO:0006935 247 0.041
hexose metabolic process GO:0019318 98 0.041
regulation of ion transport GO:0043269 215 0.041
regulation of protein localization GO:0032880 231 0.040
regulation of regulated secretory pathway GO:1903305 20 0.040
positive regulation of protein kinase activity GO:0045860 144 0.040
t cell proliferation GO:0042098 120 0.040
small gtpase mediated signal transduction GO:0007264 97 0.040
regulation of hydrolase activity GO:0051336 246 0.040
microglial cell activation involved in immune response GO:0002282 1 0.040
regulation of tumor necrosis factor biosynthetic process GO:0042534 10 0.039
macrophage activation GO:0042116 27 0.039
striated muscle cell development GO:0055002 125 0.039
regulation of lipid metabolic process GO:0019216 118 0.039
cerebral cortex development GO:0021987 86 0.039
extrinsic apoptotic signaling pathway GO:0097191 126 0.038
cellular lipid metabolic process GO:0044255 323 0.038
response to light stimulus GO:0009416 135 0.038
regulation of peptide transport GO:0090087 91 0.038
leukocyte migration GO:0050900 124 0.038
neural precursor cell proliferation GO:0061351 121 0.037
inflammatory response to antigenic stimulus GO:0002437 30 0.037
regulation of cell cycle GO:0051726 281 0.037
inorganic cation transmembrane transport GO:0098662 207 0.037
regulation of leukocyte degranulation GO:0043300 20 0.037
tumor necrosis factor production GO:0032640 50 0.037
divalent inorganic cation transport GO:0072511 178 0.036
regulation of lymphocyte activation GO:0051249 240 0.036
Human
regulation of t cell apoptotic process GO:0070232 28 0.036
myeloid leukocyte mediated immunity GO:0002444 42 0.036
peptidyl tyrosine phosphorylation GO:0018108 143 0.036
immune complex clearance by monocytes and macrophages GO:0002436 2 0.036
organic acid biosynthetic process GO:0016053 86 0.036
regulation of alpha beta t cell proliferation GO:0046640 18 0.035
detection of external stimulus GO:0009581 61 0.035
inner cell mass cell proliferation GO:0001833 15 0.035
plasma membrane organization GO:0007009 90 0.035
positive regulation of mapk cascade GO:0043410 170 0.034
single organismal cell cell adhesion GO:0016337 131 0.034
camera type eye development GO:0043010 266 0.034
jnk cascade GO:0007254 72 0.034
detection of stimulus involved in sensory perception GO:0050906 44 0.034
carbohydrate metabolic process GO:0005975 230 0.034
negative regulation of molecular function GO:0044092 258 0.034
mast cell activation involved in immune response GO:0002279 20 0.034
blood circulation GO:0008015 195 0.034
positive regulation of nervous system development GO:0051962 221 0.034
leukocyte activation involved in immune response GO:0002366 126 0.033
regulation of mitotic cell cycle GO:0007346 126 0.033
membrane organization GO:0061024 245 0.033
lymphocyte apoptotic process GO:0070227 54 0.033
positive regulation of granulocyte chemotaxis GO:0071624 12 0.033
microglial cell activation GO:0001774 3 0.033
male gamete generation GO:0048232 285 0.033
regulation of hematopoietic stem cell migration GO:2000471 1 0.033
regulation of mast cell activation GO:0033003 21 0.032
positive regulation of lymphocyte proliferation GO:0050671 70 0.032
negative regulation of lymphocyte apoptotic process GO:0070229 24 0.032
telencephalon cell migration GO:0022029 55 0.032
negative regulation of macrophage apoptotic process GO:2000110 3 0.032
gland development GO:0048732 330 0.032
regulation of peptide hormone secretion GO:0090276 75 0.032
regulation of epithelial cell proliferation GO:0050678 141 0.032
positive regulation of t cell proliferation GO:0042102 52 0.031
regulation of cytokine biosynthetic process GO:0042035 59 0.031
heart process GO:0003015 94 0.031
regulation of hypersensitivity GO:0002883 10 0.031
t cell selection GO:0045058 34 0.031
regulation of cellular response to stress GO:0080135 159 0.031
mast cell activation GO:0045576 27 0.031
ribonucleotide metabolic process GO:0009259 291 0.031
carboxylic acid biosynthetic process GO:0046394 86 0.031
peptide transport GO:0015833 133 0.031
fatty acid metabolic process GO:0006631 121 0.031
positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation GO:2000526 1 0.030
positive regulation of epithelial cell proliferation GO:0050679 68 0.030
cellular chemical homeostasis GO:0055082 215 0.030
t cell receptor signaling pathway GO:0050852 46 0.030
ion transmembrane transport GO:0034220 361 0.030
cyclic nucleotide metabolic process GO:0009187 59 0.030
negative regulation of leukocyte mediated immunity GO:0002704 29 0.030
sensory perception of mechanical stimulus GO:0050954 107 0.030
monocyte extravasation GO:0035696 2 0.029
neuron projection guidance GO:0097485 141 0.029
gliogenesis GO:0042063 141 0.029
pallium development GO:0021543 120 0.029
regulation of cytokine secretion GO:0050707 61 0.029
morphogenesis of a branching structure GO:0001763 203 0.029
regulation of interferon gamma production GO:0032649 57 0.029
regulation of alpha beta t cell activation GO:0046634 53 0.028
forebrain development GO:0030900 302 0.028
regulation of protein serine threonine kinase activity GO:0071900 157 0.028
alpha amino acid metabolic process GO:1901605 59 0.028
regulation of leukocyte differentiation GO:1902105 159 0.028
regulation of protein secretion GO:0050708 82 0.028
regulation of mast cell activation involved in immune response GO:0033006 17 0.028
regulation of extrinsic apoptotic signaling pathway GO:2001236 77 0.027
purine ribonucleotide metabolic process GO:0009150 290 0.027
regulation of interleukin 1 production GO:0032652 26 0.027
positive regulation of cytosolic calcium ion concentration GO:0007204 65 0.027
cellular protein complex assembly GO:0043623 116 0.027
peptide secretion GO:0002790 114 0.027
regulation of neuron death GO:1901214 134 0.027
ribose phosphate metabolic process GO:0019693 291 0.027
cation transmembrane transport GO:0098655 266 0.027
sensory organ morphogenesis GO:0090596 242 0.027
interleukin 1 beta secretion GO:0050702 16 0.027
detection of abiotic stimulus GO:0009582 60 0.026
t cell apoptotic process GO:0070231 39 0.026
tolerance induction GO:0002507 14 0.026
regulation of purine nucleotide metabolic process GO:1900542 169 0.026
purine containing compound metabolic process GO:0072521 311 0.026
peptidyl tyrosine modification GO:0018212 145 0.026
i kappab kinase nf kappab signaling GO:0007249 85 0.026
lymphocyte anergy GO:0002249 4 0.025
innate immune response GO:0045087 157 0.025
positive regulation of leukocyte proliferation GO:0070665 73 0.025
cytosolic calcium ion homeostasis GO:0051480 70 0.025
muscle cell development GO:0055001 133 0.025
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.025
calcium ion transport GO:0006816 159 0.025
positive regulation of interferon gamma production GO:0032729 39 0.025
learning GO:0007612 98 0.025
signal transduction in absence of ligand GO:0038034 55 0.025
locomotory behavior GO:0007626 195 0.024
organelle assembly GO:0070925 177 0.024
myeloid cell apoptotic process GO:0033028 22 0.024
response to radiation GO:0009314 165 0.024
cellular nitrogen compound catabolic process GO:0044270 280 0.024
regulation of neuron projection development GO:0010975 169 0.024
organelle localization GO:0051640 179 0.024
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 87 0.024
positive regulation of interleukin 2 production GO:0032743 19 0.024
cdc42 protein signal transduction GO:0032488 0 0.024
cytokine metabolic process GO:0042107 71 0.024
corticotropin releasing hormone secretion GO:0043396 2 0.024
regulation of establishment of protein localization GO:0070201 181 0.023
positive regulation of inflammatory response to antigenic stimulus GO:0002863 11 0.023
cytokine mediated signaling pathway GO:0019221 115 0.023
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 26 0.023
cell division GO:0051301 120 0.023
negative regulation of innate immune response GO:0045824 17 0.023
protein oligomerization GO:0051259 67 0.023
smoothened signaling pathway GO:0007224 105 0.023
positive regulation of secretion GO:0051047 130 0.023
glucose metabolic process GO:0006006 92 0.023
positive regulation of nucleotide metabolic process GO:0045981 114 0.023
regulation of organelle organization GO:0033043 289 0.023
regulation of immunoglobulin mediated immune response GO:0002889 37 0.023
nuclear division GO:0000280 158 0.022
neurohypophysis development GO:0021985 2 0.022
establishment of protein localization to organelle GO:0072594 118 0.022
positive regulation of t cell anergy GO:0002669 4 0.022
positive regulation of response to wounding GO:1903036 66 0.022
zymogen activation GO:0031638 41 0.022
regulation of angiogenesis GO:0045765 81 0.022
regulation of gliogenesis GO:0014013 50 0.022
interleukin 4 production GO:0032633 24 0.022
retina development in camera type eye GO:0060041 119 0.022
cellular response to peptide hormone stimulus GO:0071375 92 0.022
negative regulation of exocytosis GO:0045920 12 0.022
regulation of hormone levels GO:0010817 211 0.022
amide transport GO:0042886 138 0.022
cellular response to hormone stimulus GO:0032870 150 0.022
regulation of myeloid leukocyte mediated immunity GO:0002886 25 0.022
negative regulation of secretion by cell GO:1903531 54 0.022
positive regulation of hydrolase activity GO:0051345 148 0.022
humoral immune response GO:0006959 57 0.022
skeletal muscle organ development GO:0060538 163 0.022
positive regulation of lymphocyte anergy GO:0002913 4 0.022
regulation of homeostatic process GO:0032844 182 0.021
regulation of anatomical structure size GO:0090066 178 0.021
regulation of blood circulation GO:1903522 93 0.021
mast cell mediated immunity GO:0002448 20 0.021
cellularization GO:0007349 1 0.021
alpha beta t cell proliferation GO:0046633 21 0.021
hormone secretion GO:0046879 128 0.021
stress activated protein kinase signaling cascade GO:0031098 81 0.021
glial cell differentiation GO:0010001 131 0.021
telencephalon development GO:0021537 186 0.021
response to organonitrogen compound GO:0010243 246 0.021
spermatogenesis GO:0007283 284 0.021
phenol containing compound metabolic process GO:0018958 60 0.021
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.021
positive regulation of alpha beta t cell proliferation GO:0046641 12 0.021
notch signaling pathway GO:0007219 71 0.021
nucleoside phosphate metabolic process GO:0006753 338 0.021
negative regulation of cell activation GO:0050866 111 0.021
mitotic cell cycle process GO:1903047 159 0.020
b cell proliferation GO:0042100 53 0.020
regulation of antigen receptor mediated signaling pathway GO:0050854 29 0.020
b cell differentiation GO:0030183 78 0.020
cellular modified amino acid biosynthetic process GO:0042398 12 0.020
ventricular cardiac muscle tissue development GO:0003229 38 0.020
neuron migration GO:0001764 122 0.020
tumor necrosis factor biosynthetic process GO:0042533 10 0.020
regulation of cellular catabolic process GO:0031329 242 0.020
interferon gamma production GO:0032609 67 0.020
regulation of t cell proliferation GO:0042129 92 0.020
dendritic cell chemotaxis GO:0002407 7 0.020
mitotic cell cycle GO:0000278 195 0.020
nuclear transport GO:0051169 139 0.020
muscle cell differentiation GO:0042692 261 0.020
detection of stimulus GO:0051606 84 0.020
regulation of peptide secretion GO:0002791 77 0.020
positive regulation of exocytosis GO:0045921 20 0.020
carbohydrate transport GO:0008643 62 0.020
immune response activating signal transduction GO:0002757 116 0.020
cerebral cortex cell migration GO:0021795 44 0.020
positive regulation of cytokine production GO:0001819 174 0.020
asymmetric stem cell division GO:0098722 3 0.019
aromatic compound catabolic process GO:0019439 286 0.019
interleukin 1 beta production GO:0032611 30 0.019
defense response to bacterium GO:0042742 119 0.019
regulation of calcium mediated signaling GO:0050848 19 0.019
organic cyclic compound catabolic process GO:1901361 295 0.019
glycosyl compound catabolic process GO:1901658 206 0.019
negative regulation of secretion GO:0051048 61 0.019
negative regulation of t cell apoptotic process GO:0070233 18 0.019
positive regulation of immune effector process GO:0002699 107 0.019
carbohydrate homeostasis GO:0033500 128 0.019
defense response to gram positive bacterium GO:0050830 50 0.019
cellular response to acid chemical GO:0071229 68 0.019
calcium mediated signaling GO:0019722 46 0.018
t helper 1 type immune response GO:0042088 25 0.018
developmental maturation GO:0021700 193 0.018
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 55 0.018
regulation of t cell receptor signaling pathway GO:0050856 21 0.018
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 31 0.018
muscle system process GO:0003012 141 0.018
axonogenesis GO:0007409 274 0.018
cognition GO:0050890 149 0.018
blastocyst development GO:0001824 80 0.018
regulation of jun kinase activity GO:0043506 40 0.018
regulation of body fluid levels GO:0050878 162 0.018
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.018
release of sequestered calcium ion into cytosol GO:0051209 42 0.018
negative regulation of interleukin 8 secretion GO:2000483 1 0.018
response to peptide GO:1901652 136 0.018
regulation of protein transport GO:0051223 163 0.017
learning or memory GO:0007611 148 0.017
actin polymerization or depolymerization GO:0008154 54 0.017
monocarboxylic acid metabolic process GO:0032787 191 0.017
carbohydrate derivative biosynthetic process GO:1901137 183 0.017
protein localization to membrane GO:0072657 108 0.017
positive regulation of antigen receptor mediated signaling pathway GO:0050857 9 0.017
activation of mapk activity GO:0000187 59 0.017
positive regulation of growth GO:0045927 104 0.017
cellular response to peptide GO:1901653 92 0.017
positive regulation of phospholipase c activity GO:0010863 2 0.017
negative regulation of homeostatic process GO:0032845 71 0.017
asymmetric neuroblast division GO:0055059 1 0.017
negative regulation of cytokine production GO:0001818 84 0.017
regulation of purine nucleotide catabolic process GO:0033121 122 0.017
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 62 0.017
regulation of b cell proliferation GO:0030888 39 0.017
regulation of locomotion involved in locomotory behavior GO:0090325 1 0.017
regulation of oligodendrocyte differentiation GO:0048713 23 0.017
regulation of cell migration GO:0030334 219 0.017
spermatid differentiation GO:0048515 115 0.017
regulation of cd8 positive alpha beta t cell extravasation GO:2000449 3 0.017
regulation of glial cell differentiation GO:0045685 41 0.016
organonitrogen compound catabolic process GO:1901565 264 0.016
detection of molecule of bacterial origin GO:0032490 2 0.016
cardiac ventricle morphogenesis GO:0003208 50 0.016
regulation of carbohydrate metabolic process GO:0006109 75 0.016
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 51 0.016
antigen processing and presentation GO:0019882 47 0.016
glycoprotein metabolic process GO:0009100 116 0.016
regulation of chemotaxis GO:0050920 53 0.016
positive regulation of jnk cascade GO:0046330 46 0.016
glucose homeostasis GO:0042593 128 0.016
ribonucleoside metabolic process GO:0009119 245 0.016
regulation of leukocyte proliferation GO:0070663 121 0.016
natural killer cell inhibitory signaling pathway GO:0002769 2 0.016
regulation of endocytosis GO:0030100 69 0.016
regulation of t helper 2 cell cytokine production GO:2000551 3 0.016
acylglycerol biosynthetic process GO:0046463 18 0.016
response to extracellular stimulus GO:0009991 127 0.016
regulation of metal ion transport GO:0010959 106 0.016
muscle fiber development GO:0048747 76 0.016
epithalamus development GO:0021538 2 0.016
mrna transcription from rna polymerase ii promoter GO:0042789 4 0.016
cellular response to insulin stimulus GO:0032869 78 0.016
cardiac ventricle development GO:0003231 83 0.015
positive regulation of chemotaxis GO:0050921 38 0.015
positive regulation of phospholipase activity GO:0010518 3 0.015
striated muscle tissue development GO:0014706 293 0.015
response to organic cyclic compound GO:0014070 198 0.015
positive regulation of peptide secretion GO:0002793 33 0.015
ventricular compact myocardium morphogenesis GO:0003223 2 0.015
negative regulation of intracellular signal transduction GO:1902532 167 0.015
circulatory system process GO:0003013 197 0.015
g protein coupled receptor internalization GO:0002031 3 0.015
digestive tract development GO:0048565 190 0.015
transmembrane transport GO:0055085 412 0.015
positive regulation of organelle organization GO:0010638 128 0.015
positive regulation of camp mediated signaling GO:0043950 3 0.015
regulated secretory pathway GO:0045055 32 0.015
positive regulation of cell cycle GO:0045787 92 0.015
guanosine containing compound metabolic process GO:1901068 144 0.015
macula densa development GO:0072024 1 0.015
regulation of cell motility GO:2000145 236 0.015

Sit1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.026