Mus musculus

549 known processes

Wnt4

wingless-related MMTV integration site 4

(Aliases: MGC123964,Wnt-4)

Wnt4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
mesonephric epithelium development GO:0072163 94 0.995
renal tubule development GO:0061326 87 0.986
ureteric bud development GO:0001657 94 0.981
mesonephric tubule development GO:0072164 94 0.975
mesonephric duct morphogenesis GO:0072180 4 0.969
Mouse
regulation of testosterone biosynthetic process GO:2000224 2 0.968
type b pancreatic cell proliferation GO:0044342 10 0.968
polarity specification of proximal distal axis GO:0010085 2 0.967
Mouse
kidney epithelium development GO:0072073 121 0.960
establishment of organ orientation GO:0048561 1 0.958
Mouse
wnt signaling pathway GO:0016055 188 0.952
mesonephric duct formation GO:0072181 2 0.944
Mouse
nephron tubule morphogenesis GO:0072078 68 0.923
regulation of branching involved in ureteric bud morphogenesis GO:0090189 22 0.920
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 151 0.919
Zebrafish Mouse
embryonic organ morphogenesis GO:0048562 276 0.919
Mouse
canonical wnt signaling pathway involved in regulation of type b pancreatic cell proliferation GO:0044343 1 0.913
Mouse
amine metabolic process GO:0009308 45 0.909
neuron projection extension GO:1990138 64 0.904
Zebrafish Mouse
hair follicle development GO:0001942 85 0.904
Mouse
positive regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000081 1 0.901
Mouse
cervix development GO:0060067 2 0.899
Mouse
ureteric bud morphogenesis GO:0060675 62 0.897
negative regulation of bmp signaling pathway GO:0030514 35 0.896
Mouse
nephron morphogenesis GO:0072028 69 0.895
skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration GO:0014834 3 0.894
Mouse
nephron epithelium morphogenesis GO:0072088 68 0.892
mesonephric tubule morphogenesis GO:0072171 63 0.892
oviduct development GO:0060066 3 0.888
Mouse
planar cell polarity pathway involved in pericardium morphogenesis GO:0061354 2 0.887
Mouse
spemann organizer formation GO:0060061 2 0.887
Mouse
metanephric tubule development GO:0072170 18 0.886
nephron tubule development GO:0072080 84 0.885
establishment of planar polarity involved in neural tube closure GO:0090177 15 0.884
Mouse
developmental cell growth GO:0048588 84 0.880
Zebrafish Mouse
central nervous system vasculogenesis GO:0022009 3 0.880
Mouse
metanephric nephron morphogenesis GO:0072273 19 0.879
digestive tract development GO:0048565 190 0.879
Zebrafish Mouse
establishment of endothelial blood brain barrier GO:0014045 3 0.877
Mouse
negative regulation of axon guidance GO:1902668 8 0.876
Mouse
regulation of canonical wnt signaling pathway involved in controlling type b pancreatic cell proliferation GO:2000079 1 0.875
Mouse
androgen biosynthetic process GO:0006702 4 0.875
planar cell polarity pathway involved in cardiac right atrium morphogenesis GO:0061349 2 0.874
Mouse
spinal cord development GO:0021510 81 0.872
Mouse
regulation of asymmetric cell division GO:0009786 4 0.870
Mouse
renal inner medulla development GO:0072053 3 0.870
Mouse
positive regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045899 2 0.869
Mouse
nephric duct formation GO:0072179 4 0.868
Mouse
positive regulation of anagen GO:0051885 1 0.868
Mouse
morphogenesis of a branching structure GO:0001763 203 0.867
wnt signaling pathway involved in forebrain neuroblast division GO:0021874 2 0.864
Mouse
branching involved in ureteric bud morphogenesis GO:0001658 56 0.862
nephron epithelium development GO:0072009 92 0.860
lateral sprouting involved in mammary gland duct morphogenesis GO:0060599 2 0.859
Mouse
mesonephros development GO:0001823 97 0.858
epidermis development GO:0008544 187 0.856
Mouse
interleukin 8 secretion GO:0072606 3 0.852
Mouse
positive regulation of transforming growth factor beta2 production GO:0032915 2 0.848
Mouse
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 18 0.848
Mouse
paraxial mesodermal cell fate commitment GO:0048343 2 0.848
Mouse
cardiac right atrium morphogenesis GO:0003213 3 0.844
Mouse
mesonephric tubule formation GO:0072172 11 0.841
Mouse
positive regulation of interleukin 8 secretion GO:2000484 1 0.840
Mouse
regulation of cellular amine metabolic process GO:0033238 20 0.836
renal outer medulla development GO:0072054 2 0.836
Mouse
mesonephric duct development GO:0072177 5 0.836
Mouse
metanephric renal vesicle morphogenesis GO:0072283 12 0.836
Mouse
regulation of transforming growth factor beta2 production GO:0032909 2 0.835
Mouse
paraxial mesodermal cell differentiation GO:0048342 2 0.832
Mouse
cellular amino acid metabolic process GO:0006520 103 0.830
negative regulation of prostatic bud formation GO:0060686 4 0.828
Mouse
cardiac muscle tissue morphogenesis GO:0055008 44 0.824
Mouse
morphogenesis of a polarized epithelium GO:0001738 37 0.817
Mouse
axonogenesis GO:0007409 274 0.813
Zebrafish Mouse
establishment of anatomical structure orientation GO:0048560 1 0.807
Mouse
negative regulation of axon extension GO:0030517 19 0.807
Mouse
positive regulation of mesonephros development GO:0061213 20 0.806
Mouse
mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 9 0.805
Mouse
epithelial tube formation GO:0072175 130 0.800
lung field specification GO:0060424 3 0.797
Mouse
myoblast differentiation involved in skeletal muscle regeneration GO:0014835 3 0.797
Mouse
kidney morphogenesis GO:0060993 83 0.793
hypophysis morphogenesis GO:0048850 3 0.790
Mouse
inner medullary collecting duct development GO:0072061 2 0.786
Mouse
positive regulation of branching involved in lung morphogenesis GO:0061047 4 0.785
Mouse
nephron development GO:0072006 109 0.780
development of primary female sexual characteristics GO:0046545 73 0.779
sensory organ morphogenesis GO:0090596 242 0.779
Mouse
formation of primary germ layer GO:0001704 77 0.778
Mouse
alcohol metabolic process GO:0006066 116 0.776
metanephric epithelium development GO:0072207 21 0.773
uterus morphogenesis GO:0061038 2 0.770
Mouse
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 2 0.769
Mouse
regulation of interleukin 8 secretion GO:2000482 2 0.767
Mouse
regulation of cell growth GO:0001558 91 0.763
Zebrafish Mouse
appendage morphogenesis GO:0035107 149 0.763
Mouse
foregut regionalization GO:0060423 3 0.761
Mouse
cardiac muscle tissue development GO:0048738 130 0.758
Mouse
oxygen homeostasis GO:0032364 2 0.757
Mouse
regulation of organ morphogenesis GO:2000027 144 0.756
lung induction GO:0060492 3 0.748
Mouse
central nervous system morphogenesis GO:0021551 2 0.747
Mouse
neuron projection guidance GO:0097485 141 0.744
Zebrafish Mouse
regulation of bmp signaling pathway GO:0030510 60 0.741
Mouse
muscle tissue development GO:0060537 308 0.740
Mouse
small molecule biosynthetic process GO:0044283 132 0.740
kidney rudiment formation GO:0072003 3 0.734
Mouse
striated muscle tissue development GO:0014706 293 0.734
Mouse
organic hydroxy compound metabolic process GO:1901615 203 0.730
positive regulation of epithelial cell proliferation involved in lung morphogenesis GO:0060501 3 0.729
Mouse
regulation of hormone levels GO:0010817 211 0.728
skin morphogenesis GO:0043589 38 0.728
Mouse
metanephric loop of henle development GO:0072236 4 0.726
Mouse
planar cell polarity pathway involved in heart morphogenesis GO:0061346 3 0.723
Mouse
dopaminergic neuron differentiation GO:0071542 14 0.723
Mouse
mesodermal cell fate commitment GO:0001710 17 0.722
Mouse
transforming growth factor beta2 production GO:0032906 2 0.720
Mouse
chemotaxis GO:0006935 247 0.720
Zebrafish Mouse
establishment or maintenance of polarity of embryonic epithelium GO:0016332 1 0.720
Mouse
canonical wnt signaling pathway GO:0060070 130 0.718
positive regulation of cell growth GO:0030307 33 0.715
Mouse
telencephalon development GO:0021537 186 0.707
Mouse
cell cell signaling involved in cell fate commitment GO:0045168 35 0.703
paraxial mesoderm morphogenesis GO:0048340 10 0.700
Mouse
gas homeostasis GO:0033483 3 0.699
Mouse
planar cell polarity pathway involved in outflow tract morphogenesis GO:0061347 2 0.698
Mouse
renal vesicle induction GO:0072034 3 0.697
bmp signaling pathway GO:0030509 93 0.697
Mouse
regionalization GO:0003002 337 0.696
Mouse
metanephric tubule morphogenesis GO:0072173 9 0.693
trachea cartilage morphogenesis GO:0060535 4 0.691
Mouse
axon guidance GO:0007411 141 0.689
Zebrafish Mouse
regulation of cellular amino acid metabolic process GO:0006521 5 0.689
gonad development GO:0008406 141 0.689
renal vesicle development GO:0072087 17 0.688
female sex differentiation GO:0046660 84 0.687
metanephric nephron development GO:0072210 34 0.686
planar cell polarity pathway involved in cardiac muscle tissue morphogenesis GO:0061350 2 0.685
Mouse
cerebellar cortex formation GO:0021697 22 0.685
Mouse
positive regulation of cell cell adhesion mediated by cadherin GO:2000049 2 0.684
Mouse
positive regulation of hair follicle development GO:0051798 6 0.684
Mouse
regulation of chondrocyte differentiation GO:0032330 33 0.678
Mouse
neuron fate determination GO:0048664 9 0.678
Mouse
ossification GO:0001503 216 0.677
Mouse
regulation of wnt signaling pathway GO:0030111 123 0.677
Mouse
renal tubule morphogenesis GO:0061333 72 0.676
wnt signaling pathway planar cell polarity pathway GO:0060071 27 0.676
Mouse
metanephric nephron epithelium development GO:0072243 19 0.675
Mouse
regulation of kidney development GO:0090183 40 0.674
retinal ganglion cell axon guidance GO:0031290 18 0.670
non canonical wnt signaling pathway involved in heart development GO:0061341 3 0.669
Mouse
axon extension involved in axon guidance GO:0048846 14 0.666
Zebrafish Mouse
nephron tubule formation GO:0072079 20 0.663
Mouse
epithelial cell morphogenesis GO:0003382 41 0.662
epithelial tube morphogenesis GO:0060562 303 0.661
metanephros morphogenesis GO:0003338 24 0.658
hematopoietic stem cell proliferation GO:0071425 13 0.657
Mouse
negative regulation of androgen biosynthetic process GO:2000180 1 0.656
positive regulation of mesenchymal cell proliferation GO:0002053 33 0.656
Mouse
camera type eye development GO:0043010 266 0.653
male sex differentiation GO:0046661 109 0.650
cardiocyte differentiation GO:0035051 87 0.650
Mouse
muscle tissue morphogenesis GO:0060415 53 0.647
Mouse
nephric duct morphogenesis GO:0072178 7 0.637
Mouse
cardiac chamber development GO:0003205 108 0.636
Mouse
mesenchymal cell differentiation GO:0048762 107 0.633
Mouse
outflow tract morphogenesis GO:0003151 53 0.632
Mouse
cell fate determination GO:0001709 32 0.630
Mouse
regulation of axon extension GO:0030516 43 0.627
Zebrafish Mouse
bronchus development GO:0060433 10 0.627
Mouse
regulation of cellular ketone metabolic process GO:0010565 66 0.626
regulation of hair follicle development GO:0051797 9 0.625
Mouse
mesoderm formation GO:0001707 62 0.623
Mouse
branching morphogenesis of an epithelial tube GO:0048754 159 0.618
digestive tract morphogenesis GO:0048546 147 0.617
Zebrafish Mouse
embryonic limb morphogenesis GO:0030326 126 0.612
Mouse
molting cycle GO:0042303 90 0.612
Mouse
epithelial cell development GO:0002064 159 0.611
cardiac epithelial to mesenchymal transition GO:0060317 18 0.610
Mouse
embryonic epithelial tube formation GO:0001838 130 0.608
pallium development GO:0021543 120 0.607
Mouse
actin cytoskeleton organization GO:0030036 220 0.606
cell substrate adhesion GO:0031589 130 0.604
trachea development GO:0060438 18 0.603
Mouse
positive regulation of cell development GO:0010720 237 0.602
Mouse
positive regulation of protein modification process GO:0031401 299 0.587
Mouse
paramesonephric duct development GO:0061205 3 0.586
olfactory bulb interneuron development GO:0021891 7 0.583
Mouse
hindbrain formation GO:0021576 1 0.580
Mouse
negative regulation of canonical wnt signaling pathway GO:0090090 51 0.578
Mouse
neural precursor cell proliferation GO:0061351 121 0.578
Mouse
non canonical wnt signaling pathway GO:0035567 33 0.568
regulation of anagen GO:0051884 1 0.567
Mouse
regulation of canonical wnt signaling pathway GO:0060828 82 0.566
Mouse
regulation of extent of cell growth GO:0061387 52 0.565
Zebrafish Mouse
regulation of secretion GO:0051046 274 0.564
Mouse
renal system development GO:0072001 225 0.563
kidney development GO:0001822 213 0.558
somitogenesis GO:0001756 69 0.556
Mouse
skeletal muscle organ development GO:0060538 163 0.555
Mouse
planar cell polarity pathway involved in ventricular septum morphogenesis GO:0061348 2 0.551
Mouse
hormone secretion GO:0046879 128 0.550
planar cell polarity pathway involved in neural tube closure GO:0090179 14 0.550
Mouse
mesoderm development GO:0007498 100 0.549
Mouse
cell fate commitment GO:0045165 210 0.546
cardiac septum development GO:0003279 59 0.545
Mouse
cardiac muscle cell differentiation GO:0055007 69 0.545
Mouse
tertiary branching involved in mammary gland duct morphogenesis GO:0060748 3 0.544
regulation of osteoblast differentiation GO:0045667 67 0.541
Mouse
cell growth GO:0016049 130 0.539
Zebrafish Mouse
metanephros development GO:0001656 79 0.538
midbrain hindbrain boundary maturation GO:0021732 1 0.537
Mouse
regulation of cell adhesion GO:0030155 154 0.535
regulation of cell substrate adhesion GO:0010810 73 0.532
alcohol biosynthetic process GO:0046165 43 0.531
regulation of neuron differentiation GO:0045664 281 0.529
Zebrafish Mouse
positive regulation of kidney development GO:0090184 28 0.529
regulation of cell size GO:0008361 72 0.527
Zebrafish Mouse
lobar bronchus development GO:0060482 6 0.527
Mouse
forebrain development GO:0030900 302 0.526
embryonic skeletal system development GO:0048706 120 0.525
Mouse
negative regulation of wnt signaling pathway GO:0030178 73 0.525
Mouse
cardiac chamber morphogenesis GO:0003206 93 0.523
Mouse
cardiac septum morphogenesis GO:0060411 46 0.522
Mouse
cop9 signalosome assembly GO:0010387 2 0.520
Mouse
cochlea morphogenesis GO:0090103 22 0.519
Mouse
establishment of planar polarity GO:0001736 28 0.519
Mouse
regulation of metanephros development GO:0072215 15 0.517
Mouse
regulation of mesenchymal cell proliferation GO:0010464 37 0.517
Mouse
neural tube formation GO:0001841 108 0.513
Mouse
establishment of planar polarity involved in nephron morphogenesis GO:0072046 1 0.511
Mouse
cellular amine metabolic process GO:0044106 44 0.510
appendage development GO:0048736 166 0.510
Mouse
peptidyl serine modification GO:0018209 83 0.508
Mouse
central nervous system neuron differentiation GO:0021953 162 0.508
Mouse
blood coagulation GO:0007596 76 0.508
Mouse
cellular ketone metabolic process GO:0042180 84 0.504
single organism cell adhesion GO:0098602 156 0.501
digestive system development GO:0055123 200 0.499
Zebrafish Mouse
ubiquitin dependent smad protein catabolic process GO:0030579 2 0.496
Mouse
regulation of muscle tissue development GO:1901861 97 0.495
Mouse
muscle cell differentiation GO:0042692 261 0.495
negative regulation of alcohol biosynthetic process GO:1902931 4 0.493
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.489
anatomical structure regression GO:0060033 9 0.489
Mouse
gastrulation GO:0007369 116 0.488
Zebrafish Mouse
stem cell differentiation GO:0048863 268 0.488
Mouse
hair cycle phase GO:0044851 16 0.487
Mouse
negative regulation of cell proliferation GO:0008285 296 0.485
Mouse
labyrinthine layer blood vessel development GO:0060716 21 0.484
Mouse
cardiac ventricle development GO:0003231 83 0.484
Mouse
regulation of ketone biosynthetic process GO:0010566 2 0.484
metencephalon development GO:0022037 89 0.482
Mouse
regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003339 5 0.481
Mouse
negative regulation of molecular function GO:0044092 258 0.480
Mouse
positive regulation of kinase activity GO:0033674 155 0.479
Mouse
regulation of mesonephros development GO:0061217 24 0.477
Mouse
positive regulation of protein serine threonine kinase activity GO:0071902 106 0.477
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.473
establishment of tissue polarity GO:0007164 28 0.471
Mouse
cytokine production GO:0001816 319 0.471
Mouse
t cell proliferation GO:0042098 120 0.470
ear development GO:0043583 200 0.470
Mouse
adherens junction organization GO:0034332 28 0.468
skin development GO:0043588 220 0.467
Mouse
midbrain hindbrain boundary maturation during brain development GO:0022004 1 0.467
Mouse
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 26 0.467
Mouse
heart morphogenesis GO:0003007 178 0.467
Mouse
cellular response to organonitrogen compound GO:0071417 145 0.466
Mouse
hair cycle GO:0042633 90 0.466
Mouse
endocrine system development GO:0035270 98 0.462
maintenance of cell number GO:0098727 3 0.461
Mouse
inner ear morphogenesis GO:0042472 101 0.459
Mouse
oocyte differentiation GO:0009994 35 0.459
positive regulation of protein phosphorylation GO:0001934 242 0.458
Mouse
negative regulation of cytokine production GO:0001818 84 0.458
Mouse
apical junction assembly GO:0043297 15 0.458
Mouse
hindbrain morphogenesis GO:0021575 46 0.458
Mouse
lymphocyte differentiation GO:0030098 242 0.456
regulation of cytokine production GO:0001817 266 0.455
Mouse
negative regulation of mesenchymal cell proliferation GO:0072201 3 0.454
Mouse
cell type specific apoptotic process GO:0097285 268 0.454
Mouse
apoptotic process involved in patterning of blood vessels GO:1902262 6 0.453
Mouse
olfactory bulb development GO:0021772 30 0.453
Mouse
regulation of cell migration GO:0030334 219 0.446
cartilage morphogenesis GO:0060536 11 0.445
Mouse
lipid biosynthetic process GO:0008610 179 0.439
regulation of establishment of planar polarity GO:0090175 28 0.439
Mouse
mesenchyme morphogenesis GO:0072132 32 0.437
Mouse
regulation of stem cell proliferation GO:0072091 78 0.437
Mouse
metanephric nephron tubule development GO:0072234 16 0.435
Mouse
rho protein signal transduction GO:0007266 32 0.435
positive regulation of stem cell proliferation GO:2000648 59 0.430
Mouse
negative chemotaxis GO:0050919 14 0.429
Mouse
female gonad development GO:0008585 71 0.429
fibroblast growth factor production GO:0090269 4 0.427
Mouse
morphogenesis of a branching epithelium GO:0061138 193 0.426
regulation of cell cycle g2 m phase transition GO:1902749 10 0.426
Mouse
limb development GO:0060173 166 0.426
Mouse
cell surface receptor signaling pathway involved in heart development GO:0061311 15 0.425
Mouse
non canonical wnt signaling pathway via jnk cascade GO:0038031 3 0.424
Mouse
transforming growth factor beta receptor signaling pathway GO:0007179 71 0.423
Mouse
negative regulation of cartilage development GO:0061037 17 0.422
Mouse
regulation of establishment of planar polarity involved in neural tube closure GO:0090178 15 0.422
Mouse
regulation of embryonic development GO:0045995 71 0.419
Mouse
adherens junction assembly GO:0034333 22 0.419
regulation of transferase activity GO:0051338 263 0.417
Mouse
developmental growth involved in morphogenesis GO:0060560 138 0.417
Zebrafish Mouse
positive regulation of cellular amine metabolic process GO:0033240 5 0.412
regulation of cell cell adhesion mediated by cadherin GO:2000047 2 0.409
Mouse
cardiac muscle cell proliferation GO:0060038 31 0.408
Mouse
regulation of cell motility GO:2000145 236 0.408
gland development GO:0048732 330 0.407
apoptotic signaling pathway GO:0097190 306 0.405
muscle fiber development GO:0048747 76 0.404
Mouse
fibroblast growth factor receptor signaling pathway GO:0008543 46 0.402
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 3 0.399
Mouse
embryonic digit morphogenesis GO:0042733 56 0.396
Mouse
platelet activation GO:0030168 40 0.396
Mouse
cell matrix adhesion GO:0007160 68 0.396
thyroid stimulating hormone secreting cell differentiation GO:0060129 4 0.395
neural tube closure GO:0001843 90 0.393
Mouse
negative regulation of testosterone biosynthetic process GO:2000225 1 0.391
placenta blood vessel development GO:0060674 31 0.390
Mouse
stem cell proliferation GO:0072089 117 0.388
Mouse
axis elongation involved in somitogenesis GO:0090245 4 0.385
Mouse
urogenital system development GO:0001655 261 0.384
negative regulation of chondrocyte differentiation GO:0032331 13 0.383
Mouse
stem cell development GO:0048864 219 0.381
Mouse
peptide transport GO:0015833 133 0.379
regulation of apoptotic signaling pathway GO:2001233 197 0.378
somite development GO:0061053 81 0.378
Mouse
regulation of secretion by cell GO:1903530 249 0.377
Mouse
positive regulation of meiosis GO:0045836 14 0.377
atrial cardiac muscle tissue development GO:0003228 5 0.377
Mouse
regulation of steroid biosynthetic process GO:0050810 26 0.375
forebrain regionalization GO:0021871 25 0.374
Mouse
positive regulation of cell adhesion GO:0045785 80 0.374
cellular response to starvation GO:0009267 57 0.373
regulation of body fluid levels GO:0050878 162 0.373
Mouse
regulation of system process GO:0044057 200 0.371
positive regulation of cell projection organization GO:0031346 95 0.361
Mouse
protein secretion GO:0009306 111 0.352
Mouse
anterior posterior axis specification embryo GO:0008595 9 0.352
Mouse
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.352
Mouse
positive regulation of g2 m transition of mitotic cell cycle GO:0010971 5 0.352
Mouse
embryonic appendage morphogenesis GO:0035113 126 0.351
Mouse
olfactory bulb interneuron differentiation GO:0021889 12 0.351
Mouse
forebrain neuroblast division GO:0021873 9 0.346
Mouse
regulation of interleukin 6 production GO:0032675 55 0.343
Mouse
regulation of reproductive process GO:2000241 66 0.342
Mouse
angiogenesis GO:0001525 201 0.342
Mouse
negative regulation of hormone metabolic process GO:0032351 4 0.341
positive regulation of synapse assembly GO:0051965 18 0.338
Mouse
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 68 0.338
Mouse
negative regulation of apoptotic signaling pathway GO:2001234 104 0.338
forebrain anterior posterior pattern specification GO:0021797 5 0.335
Mouse
wnt signaling pathway calcium modulating pathway GO:0007223 2 0.333
Mouse
positive regulation of transcription initiation from rna polymerase ii promoter GO:0060261 5 0.333
Mouse
positive regulation of cell morphogenesis involved in differentiation GO:0010770 72 0.332
Mouse
insulin secretion GO:0030073 89 0.331
stem cell maintenance GO:0019827 130 0.331
Mouse
response to nutrient levels GO:0031667 109 0.330
regulation of protein serine threonine kinase activity GO:0071900 157 0.330
Mouse
regulation of hormone secretion GO:0046883 88 0.330
trachea cartilage development GO:0060534 8 0.329
Mouse
paraxial mesoderm development GO:0048339 18 0.329
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 106 0.328
Mouse
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 3 0.327
Mouse
positive regulation of mapk cascade GO:0043410 170 0.322
Mouse
hindbrain development GO:0030902 128 0.318
Mouse
guanosine containing compound catabolic process GO:1901069 144 0.316
morphogenesis of embryonic epithelium GO:0016331 159 0.315
cerebellum formation GO:0021588 1 0.315
Mouse
limb morphogenesis GO:0035108 149 0.315
Mouse
cochlea development GO:0090102 35 0.315
Mouse
negative regulation of protein metabolic process GO:0051248 282 0.314
Mouse
somatotropin secreting cell differentiation GO:0060126 4 0.314
endothelium development GO:0003158 45 0.314
Mouse
response to parathyroid hormone GO:0071107 3 0.313
Mouse
fungiform papilla development GO:0061196 6 0.313
Mouse
positive regulation of cellular component biogenesis GO:0044089 94 0.312
mesenchymal cell proliferation GO:0010463 44 0.310
Mouse
embryonic placenta development GO:0001892 98 0.310
Mouse
positive regulation of actin filament bundle assembly GO:0032233 11 0.309
neuroblast proliferation GO:0007405 49 0.308
Mouse
regulation of mitotic cell cycle GO:0007346 126 0.307
Mouse
coagulation GO:0050817 78 0.307
Mouse
mesenchymal cell development GO:0014031 93 0.307
Mouse
columnar cuboidal epithelial cell differentiation GO:0002065 82 0.306
myeloid cell differentiation GO:0030099 233 0.305
mammary gland epithelial cell proliferation GO:0033598 24 0.305
Mouse
neuron projection extension involved in neuron projection guidance GO:1902284 14 0.302
Zebrafish Mouse
positive regulation of stress activated mapk cascade GO:0032874 48 0.300
Mouse
regulation of cellular response to stress GO:0080135 159 0.297
Mouse
macromolecule catabolic process GO:0009057 281 0.296
Mouse
chondrocyte differentiation GO:0002062 72 0.296
Mouse
columnar cuboidal epithelial cell development GO:0002066 29 0.296
Mouse
epithelial mesenchymal cell signaling GO:0060684 7 0.295
Mouse
negative regulation of steroid metabolic process GO:0045939 8 0.294
endoderm development GO:0007492 45 0.294
Mouse
cellular response to molecule of bacterial origin GO:0071219 83 0.292
Mouse
response to organonitrogen compound GO:0010243 246 0.292
Mouse
pituitary gland development GO:0021983 38 0.291
positive regulation of cell cycle phase transition GO:1901989 17 0.290
Mouse
regulation of neuron projection development GO:0010975 169 0.287
Zebrafish Mouse
regulation of cellular response to growth factor stimulus GO:0090287 82 0.287
carbohydrate metabolic process GO:0005975 230 0.286
regulation of actin filament based process GO:0032970 99 0.286
cerebellar granular layer development GO:0021681 13 0.286
Mouse
placenta development GO:0001890 140 0.285
Mouse
regulation of protein tyrosine kinase activity GO:0061097 17 0.285
Mouse
response to growth factor GO:0070848 198 0.284
mitotic cell cycle GO:0000278 195 0.283
Mouse
lung development GO:0030324 164 0.282
Mouse
somatic stem cell maintenance GO:0035019 47 0.281
Mouse
hematopoietic progenitor cell differentiation GO:0002244 143 0.281
organic hydroxy compound biosynthetic process GO:1901617 77 0.280
positive regulation of striated muscle tissue development GO:0045844 31 0.279
Mouse
positive regulation of cell migration GO:0030335 109 0.278
Mouse
mesoderm morphogenesis GO:0048332 64 0.277
Mouse
development of primary male sexual characteristics GO:0046546 88 0.276
peptidyl threonine modification GO:0018210 31 0.276
Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 247 0.276
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 43 0.275
Mouse
regulation of morphogenesis of a branching structure GO:0060688 53 0.273
Mouse
collecting duct development GO:0072044 11 0.273
Mouse
regulation of cartilage development GO:0061035 44 0.273
Mouse
microtubule cytoskeleton organization GO:0000226 157 0.272
Mouse
peptide hormone secretion GO:0030072 109 0.272
positive regulation of cell substrate adhesion GO:0010811 47 0.272
neural tube patterning GO:0021532 43 0.269
Mouse
mesenchyme development GO:0060485 152 0.267
Mouse
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 61 0.266
Mouse
forebrain neuron differentiation GO:0021879 52 0.265
Mouse
establishment of planar polarity of embryonic epithelium GO:0042249 16 0.263
Mouse
lung morphogenesis GO:0060425 50 0.262
Mouse
respiratory tube development GO:0030323 167 0.262
Mouse
artery development GO:0060840 53 0.262
Mouse
regulation of synapse assembly GO:0051963 29 0.261
Mouse
positive regulation of secretion by cell GO:1903532 114 0.261
Mouse
regulation of epithelial cell migration GO:0010632 35 0.259
Mouse
regulation of cysteine type endopeptidase activity GO:2000116 65 0.259
Mouse
lymphocyte apoptotic process GO:0070227 54 0.258
Mouse
non canonical wnt signaling pathway via mapk cascade GO:0038030 3 0.258
Mouse
positive regulation of interleukin 1 beta production GO:0032731 16 0.257
Mouse
positive regulation of neuron differentiation GO:0045666 141 0.255
Mouse
embryonic heart tube morphogenesis GO:0003143 51 0.252
Mouse
vagina development GO:0060068 11 0.252
Mouse
regulation of protein kinase activity GO:0045859 232 0.251
Mouse
protein catabolic process GO:0030163 221 0.251
Mouse
positive regulation of cell cycle GO:0045787 92 0.251
response to extracellular stimulus GO:0009991 127 0.250
retina development in camera type eye GO:0060041 119 0.250
mesenchymal to epithelial transition GO:0060231 12 0.250
positive regulation of nervous system development GO:0051962 221 0.249
Mouse
mesenchymal stem cell maintenance involved in nephron morphogenesis GO:0072038 7 0.248
Mouse
organ induction GO:0001759 21 0.247
Mouse
negative regulation of epithelial cell proliferation GO:0050680 64 0.247
Mouse
positive regulation of neuroblast proliferation GO:0002052 19 0.246
peripheral nervous system neuron axonogenesis GO:0048936 3 0.245
cellular macromolecule catabolic process GO:0044265 206 0.244
Mouse
myoblast differentiation GO:0045445 52 0.243
Mouse
regulation of axon diameter GO:0031133 6 0.243
Mouse
spemann organizer formation at the anterior end of the primitive streak GO:0060064 1 0.242
Mouse
renal vesicle formation GO:0072033 8 0.241
neuroepithelial cell differentiation GO:0060563 37 0.239
skeletal muscle fiber development GO:0048741 58 0.239
Mouse
leukocyte differentiation GO:0002521 342 0.238
cardiac ventricle morphogenesis GO:0003208 50 0.236
muscle cell development GO:0055001 133 0.234
Mouse
forebrain generation of neurons GO:0021872 63 0.234
Mouse
negative regulation of synapse assembly GO:0051964 3 0.233
Mouse
wound healing GO:0042060 157 0.232
regulation of map kinase activity GO:0043405 120 0.232
Mouse
peptidyl amino acid modification GO:0018193 336 0.232
Mouse
developmental induction GO:0031128 34 0.231
asymmetric cell division GO:0008356 8 0.230
Mouse
cell junction assembly GO:0034329 52 0.229
cellular response to fibroblast growth factor stimulus GO:0044344 47 0.229
central nervous system neuron development GO:0021954 67 0.227
Mouse
positive regulation of endopeptidase activity GO:0010950 43 0.225
Mouse
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 40 0.225
Mouse
anagen GO:0042640 13 0.224
Mouse
nitrogen compound transport GO:0071705 271 0.224
positive regulation of ossification GO:0045778 47 0.223
Mouse
protein processing GO:0016485 163 0.222
Mouse
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 61 0.221
Mouse
striated muscle cell development GO:0055002 125 0.221
Mouse
proteolysis involved in cellular protein catabolic process GO:0051603 147 0.221
Mouse
hormone biosynthetic process GO:0042446 16 0.220
negative regulation of protein modification process GO:0031400 163 0.219
Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 93 0.218
Mouse
organ growth GO:0035265 117 0.218
Mouse
peptidyl tyrosine modification GO:0018212 145 0.217
Mouse
lateral inhibition GO:0046331 1 0.217
neurotransmitter secretion GO:0007269 62 0.216
Mouse
tube formation GO:0035148 140 0.215
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 112 0.215
Mouse
tube closure GO:0060606 91 0.214
Mouse

Wnt4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Disease DO term ID Size Probability Func Analog Org