Rattus norvegicus

41 known processes

Aanat

arylalkylamine N-acetyltransferase

(Aliases: AA-NAT,Nat4)

Aanat biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to inorganic substance GO:0010035 377 0.358
cation transport GO:0006812 382 0.255
tissue development GO:0009888 252 0.150
protein complex assembly GO:0006461 263 0.135
macromolecular complex assembly GO:0065003 273 0.129
cellular component biogenesis GO:0044085 368 0.120
response to peptide hormone GO:0043434 278 0.102
transmembrane transport GO:0055085 412 0.091
regulation of rna metabolic process GO:0051252 391 0.087
rna biosynthetic process GO:0032774 380 0.077
protein complex biogenesis GO:0070271 263 0.075
positive regulation of signaling GO:0023056 270 0.074
protein oligomerization GO:0051259 191 0.074
neuron differentiation GO:0030182 368 0.067
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.065
response to corticosteroid GO:0031960 235 0.063
circulatory system process GO:0003013 183 0.063
protein homooligomerization GO:0051260 91 0.060
macromolecular complex subunit organization GO:0043933 339 0.058
brain development GO:0007420 247 0.058
cellular response to oxygen containing compound GO:1901701 386 0.057
Human
metal ion transport GO:0030001 289 0.056
positive regulation of gene expression GO:0010628 244 0.056
oxoacid metabolic process GO:0043436 290 0.056
rna metabolic process GO:0016070 406 0.055
regulation of nucleic acid templated transcription GO:1903506 380 0.055
positive regulation of cell communication GO:0010647 271 0.054
organophosphate metabolic process GO:0019637 370 0.054
response to oxygen levels GO:0070482 265 0.054
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.053
carboxylic acid transport GO:0046942 115 0.053
response to transition metal nanoparticle GO:1990267 122 0.052
monovalent inorganic cation transport GO:0015672 172 0.052
eye development GO:0001654 50 0.051
lens development in camera type eye GO:0002088 13 0.051
nucleic acid templated transcription GO:0097659 379 0.050
intracellular transport GO:0046907 185 0.050
protein complex subunit organization GO:0071822 302 0.048
regulation of phosphate metabolic process GO:0019220 349 0.048
ion transmembrane transport GO:0034220 365 0.048
secretion GO:0046903 307 0.048
organic acid metabolic process GO:0006082 292 0.047
nucleobase containing small molecule metabolic process GO:0055086 316 0.047
response to carbohydrate GO:0009743 183 0.046
response to metal ion GO:0010038 253 0.046
negative regulation of cellular metabolic process GO:0031324 281 0.046
anion transport GO:0006820 178 0.046
cell projection organization GO:0030030 302 0.045
regulation of cellular localization GO:0060341 263 0.045
second messenger mediated signaling GO:0019932 51 0.045
response to hexose GO:0009746 144 0.045
regulation of multicellular organismal development GO:2000026 376 0.044
sensory organ development GO:0007423 74 0.044
positive regulation of phosphate metabolic process GO:0045937 262 0.044
regulation of transcription dna templated GO:0006355 374 0.044
organelle organization GO:0006996 266 0.043
cellular component assembly GO:0022607 360 0.043
purine ribonucleotide metabolic process GO:0009150 227 0.043
carboxylic acid metabolic process GO:0019752 289 0.043
epithelium development GO:0060429 96 0.043
regulation of phosphorus metabolic process GO:0051174 349 0.041
positive regulation of cell proliferation GO:0008284 249 0.041
homeostatic process GO:0042592 331 0.040
negative regulation of cell communication GO:0010648 158 0.040
response to monosaccharide GO:0034284 159 0.040
neurological system process GO:0050877 219 0.040
eye morphogenesis GO:0048592 4 0.040
negative regulation of nucleic acid templated transcription GO:1903507 117 0.039
purine nucleotide metabolic process GO:0006163 229 0.038
positive regulation of biosynthetic process GO:0009891 319 0.038
cell cell signaling GO:0007267 335 0.038
cellular response to stress GO:0033554 269 0.037
striated muscle contraction GO:0006941 44 0.037
regulation of system process GO:0044057 208 0.037
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.037
olfactory learning GO:0008355 1 0.037
negative regulation of multicellular organismal process GO:0051241 203 0.037
negative regulation of metabolic process GO:0009892 331 0.036
positive regulation of nucleic acid templated transcription GO:1903508 197 0.036
positive regulation of rna biosynthetic process GO:1902680 197 0.036
cellular response to endogenous stimulus GO:0071495 377 0.036
Human
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.035
action potential GO:0001508 54 0.035
vesicle mediated transport GO:0016192 181 0.034
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.034
cellular chemical homeostasis GO:0055082 247 0.034
purine containing compound metabolic process GO:0072521 253 0.033
central nervous system development GO:0007417 311 0.033
potassium ion transport GO:0006813 97 0.033
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.033
cell type specific apoptotic process GO:0097285 134 0.033
organonitrogen compound biosynthetic process GO:1901566 167 0.032
Human
apoptotic process GO:0006915 381 0.032
regulation of rna biosynthetic process GO:2001141 381 0.032
nucleoside phosphate metabolic process GO:0006753 283 0.032
renal system development GO:0072001 67 0.032
neuronal action potential GO:0019228 35 0.032
transcription from rna polymerase ii promoter GO:0006366 252 0.032
nucleotide metabolic process GO:0009117 279 0.032
nitrogen compound transport GO:0071705 229 0.031
organic anion transport GO:0015711 132 0.031
camera type eye development GO:0043010 48 0.030
transcription dna templated GO:0006351 377 0.030
positive regulation of transcription dna templated GO:0045893 197 0.030
response to vitamin GO:0033273 131 0.029
cellular homeostasis GO:0019725 252 0.029
cellular response to nitrogen compound GO:1901699 210 0.029
Human
response to peptide GO:1901652 292 0.029
cellular ion homeostasis GO:0006873 184 0.029
ribose phosphate metabolic process GO:0019693 235 0.029
dorsal ventral axon guidance GO:0033563 1 0.028
response to acid chemical GO:0001101 222 0.028
secretion by cell GO:0032940 248 0.028
response to purine containing compound GO:0014074 126 0.027
carbohydrate derivative catabolic process GO:1901136 147 0.027
single organism biosynthetic process GO:0044711 342 0.027
negative regulation of macromolecule metabolic process GO:0010605 260 0.026
regulation of membrane potential GO:0042391 110 0.026
organ morphogenesis GO:0009887 75 0.025
positive regulation of cellular biosynthetic process GO:0031328 295 0.025
neuron development GO:0048666 286 0.025
leucine transport GO:0015820 2 0.025
reproductive process GO:0022414 372 0.025
multicellular organismal reproductive process GO:0048609 233 0.025
negative regulation of rna metabolic process GO:0051253 123 0.025
ribonucleotide metabolic process GO:0009259 231 0.024
epithelial cell differentiation GO:0030855 71 0.024
anatomical structure morphogenesis GO:0009653 298 0.024
regulation of signal transduction GO:0009966 318 0.024
positive regulation of molecular function GO:0044093 230 0.024
somatic stem cell maintenance GO:0035019 2 0.024
positive regulation of signal transduction GO:0009967 175 0.024
protein heterooligomerization GO:0051291 89 0.023
biological adhesion GO:0022610 110 0.023
developmental process involved in reproduction GO:0003006 159 0.023
programmed cell death GO:0012501 392 0.023
neuron projection development GO:0031175 273 0.023
positive regulation of phosphorus metabolic process GO:0010562 262 0.022
cellular calcium ion homeostasis GO:0006874 160 0.022
head development GO:0060322 247 0.022
amino acid transport GO:0006865 70 0.022
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.022
positive regulation of rna metabolic process GO:0051254 203 0.022
carbohydrate derivative metabolic process GO:1901135 346 0.022
negative regulation of rna biosynthetic process GO:1902679 118 0.022
cellular divalent inorganic cation homeostasis GO:0072503 162 0.022
kidney development GO:0001822 67 0.022
regulation of phosphorylation GO:0042325 248 0.022
cellular catabolic process GO:0044248 295 0.022
g protein coupled receptor signaling pathway GO:0007186 242 0.021
branched chain amino acid transport GO:0015803 2 0.021
single organism reproductive process GO:0044702 297 0.021
response to external biotic stimulus GO:0043207 221 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.021
response to estrogen GO:0043627 232 0.021
inorganic ion transmembrane transport GO:0098660 229 0.021
response to radiation GO:0009314 137 0.021
sexual reproduction GO:0019953 148 0.021
negative regulation of cell proliferation GO:0008285 119 0.021
divalent inorganic cation homeostasis GO:0072507 165 0.020
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.020
response to hypoxia GO:0001666 231 0.020
olfactory behavior GO:0042048 2 0.020
regulation of cellular component organization GO:0051128 368 0.020
cellular response to gonadotropin stimulus GO:0071371 17 0.020
response to glucose GO:0009749 136 0.020
regulation of ion transport GO:0043269 245 0.019
positive regulation of apoptotic process GO:0043065 154 0.019
negative regulation of cellular biosynthetic process GO:0031327 161 0.019
negative regulation of gene expression GO:0010629 199 0.019
reproductive system development GO:0061458 128 0.019
regulation of molecular function GO:0065009 398 0.019
forebrain development GO:0030900 98 0.019
regulation of blood pressure GO:0008217 83 0.019
embryonic neurocranium morphogenesis GO:0048702 2 0.019
regulation of mapk cascade GO:0043408 116 0.019
positive regulation of cell death GO:0010942 184 0.019
regulation of protein metabolic process GO:0051246 289 0.019
positive regulation of multicellular organismal process GO:0051240 387 0.018
muscle system process GO:0003012 115 0.018
response to cytokine GO:0034097 215 0.018
positive regulation of membrane potential GO:0045838 16 0.018
axon development GO:0061564 96 0.018
macromolecule localization GO:0033036 252 0.018
organic substance catabolic process GO:1901575 316 0.018
transmission of nerve impulse GO:0019226 42 0.018
morphogenesis of an epithelium GO:0002009 20 0.018
single organism catabolic process GO:0044712 283 0.018
sodium ion transport GO:0006814 82 0.018
response to estradiol GO:0032355 164 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
cell adhesion GO:0007155 110 0.017
positive regulation of secretion by cell GO:1903532 128 0.017
urogenital system development GO:0001655 78 0.017
response to calcium ion GO:0051592 59 0.017
blood circulation GO:0008015 183 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.017
cellular cation homeostasis GO:0030003 180 0.017
regulation of anatomical structure size GO:0090066 135 0.017
single organism intracellular transport GO:1902582 166 0.017
nucleoside phosphate biosynthetic process GO:1901293 102 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
protein localization GO:0008104 191 0.017
response to testosterone GO:0033574 55 0.016
cell cycle GO:0007049 101 0.016
cellular hormone metabolic process GO:0034754 49 0.016
Human
response to oxidative stress GO:0006979 186 0.016
regulation of neuron differentiation GO:0045664 208 0.016
cation transmembrane transport GO:0098655 263 0.016
positive regulation of programmed cell death GO:0043068 157 0.016
regulation of catalytic activity GO:0050790 304 0.016
heart morphogenesis GO:0003007 3 0.016
organophosphate biosynthetic process GO:0090407 143 0.016
camp metabolic process GO:0046058 63 0.016
regulation of nervous system development GO:0051960 264 0.016
regulation of hormone levels GO:0010817 187 0.016
Human
reproduction GO:0000003 245 0.015
negative regulation of signal transduction GO:0009968 83 0.015
multicellular organismal signaling GO:0035637 44 0.015
regulation of nucleotide metabolic process GO:0006140 117 0.015
neuron projection morphogenesis GO:0048812 122 0.015
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
multicellular organism reproduction GO:0032504 233 0.015
intracellular signal transduction GO:0035556 314 0.015
calcium ion homeostasis GO:0055074 162 0.015
negative regulation of phosphate metabolic process GO:0045936 80 0.015
chemosensory behavior GO:0007635 2 0.014
positive regulation of developmental process GO:0051094 283 0.014
negative regulation of cell development GO:0010721 82 0.014
regulation of secretion by cell GO:1903530 208 0.014
cell projection morphogenesis GO:0048858 123 0.014
positive regulation of phosphorylation GO:0042327 177 0.014
negative regulation of signaling GO:0023057 157 0.014
cellular response to hypoxia GO:0071456 51 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.014
regulation of neurogenesis GO:0050767 247 0.014
chemical homeostasis GO:0048878 292 0.014
camera type eye morphogenesis GO:0048593 2 0.014
cardiac muscle contraction GO:0060048 27 0.014
aging GO:0007568 241 0.013
insulin like growth factor receptor signaling pathway GO:0048009 3 0.013
anterior posterior pattern specification GO:0009952 1 0.013
organophosphate catabolic process GO:0046434 148 0.013
cytoskeleton organization GO:0007010 111 0.013
cellular response to acid chemical GO:0071229 75 0.013
cellular lipid metabolic process GO:0044255 208 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
gland development GO:0048732 155 0.013
regulation of muscle cell apoptotic process GO:0010660 26 0.013
regulation of blood circulation GO:1903522 110 0.013
embryonic pattern specification GO:0009880 1 0.013
regulation of vasoconstriction GO:0019229 44 0.013
hematopoietic progenitor cell differentiation GO:0002244 2 0.013
adult locomotory behavior GO:0008344 4 0.013
oxidation reduction process GO:0055114 304 0.013
amide transport GO:0042886 105 0.013
response to histamine GO:0034776 3 0.013
mesenchymal to epithelial transition GO:0060231 3 0.013
protein tetramerization GO:0051262 38 0.012
cellular response to inorganic substance GO:0071241 65 0.012
aromatic compound catabolic process GO:0019439 168 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
protein phosphorylation GO:0006468 345 0.012
lens fiber cell differentiation GO:0070306 3 0.012
axis specification GO:0009798 4 0.012
l glutamate import GO:0051938 2 0.012
morphogenesis of embryonic epithelium GO:0016331 3 0.012
cellular ketone metabolic process GO:0042180 51 0.012
response to amino acid GO:0043200 75 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
circulatory system development GO:0072359 134 0.012
rhythmic process GO:0048511 156 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
response to growth factor GO:0070848 189 0.012
tube formation GO:0035148 3 0.012
cellular response to lipid GO:0071396 201 0.012
nucleoside metabolic process GO:0009116 179 0.012
fear response GO:0042596 9 0.011
purine containing compound biosynthetic process GO:0072522 85 0.011
establishment of protein localization GO:0045184 141 0.011
regulation of tube size GO:0035150 89 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
thyroid gland development GO:0030878 1 0.011
negative regulation of developmental process GO:0051093 125 0.011
peptide transport GO:0015833 97 0.011
sensory perception GO:0007600 101 0.011
regulation of protein modification process GO:0031399 194 0.011
response to vitamin a GO:0033189 36 0.011
signal release GO:0023061 145 0.011
regulation of ion transmembrane transporter activity GO:0032412 48 0.011
purine containing compound catabolic process GO:0072523 138 0.011
defecation GO:0030421 1 0.011
cardiac ventricle development GO:0003231 1 0.011
metal ion homeostasis GO:0055065 186 0.011
mesoderm development GO:0007498 2 0.011
heart contraction GO:0060047 57 0.011
response to zinc ion GO:0010043 39 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
gastrulation GO:0007369 2 0.011
purine ribonucleotide catabolic process GO:0009154 136 0.011
synaptic transmission GO:0007268 235 0.011
cellular response to monosaccharide stimulus GO:0071326 67 0.011
catabolic process GO:0009056 351 0.011
positive regulation of nervous system development GO:0051962 178 0.011
vascular process in circulatory system GO:0003018 96 0.010
ribonucleotide catabolic process GO:0009261 136 0.010
gamete generation GO:0007276 124 0.010
anion transmembrane transport GO:0098656 77 0.010
regulation of blood vessel size GO:0050880 89 0.010
regulation of peptide hormone secretion GO:0090276 80 0.010
cellular response to abiotic stimulus GO:0071214 85 0.010
reproductive structure development GO:0048608 128 0.010
cellular response to external stimulus GO:0071496 118 0.010
positive regulation of long term synaptic potentiation GO:1900273 4 0.010
negative regulation of transcription dna templated GO:0045892 116 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
cellular glucose homeostasis GO:0001678 66 0.010
negative regulation of metanephros development GO:0072217 2 0.010
purine ribonucleoside metabolic process GO:0046128 168 0.010
negative regulation of cellular component organization GO:0051129 83 0.010
chromosome segregation GO:0007059 2 0.010
response to nutrient levels GO:0031667 370 0.010
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.010
regulation of purine nucleotide metabolic process GO:1900542 115 0.010
regulation of kinase activity GO:0043549 117 0.010
tongue morphogenesis GO:0043587 3 0.010

Aanat disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.062
disease of anatomical entity DOID:7 0 0.062
urinary system disease DOID:18 0 0.055
kidney disease DOID:557 0 0.055
sensory system disease DOID:0050155 0 0.055
eye and adnexa disease DOID:1492 0 0.055
eye disease DOID:5614 0 0.055
disease of metabolism DOID:0014667 0 0.017
acquired metabolic disease DOID:0060158 0 0.017
nutrition disease DOID:374 0 0.017
gastrointestinal system disease DOID:77 0 0.015
overnutrition DOID:654 0 0.012
obesity DOID:9970 0 0.012
endocrine system disease DOID:28 0 0.011
central nervous system disease DOID:331 0 0.011