IMP

Process View

Rattus norvegicus

2 genes annotated in rat

negative regulation of metanephros development

Any process that decreases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in rat Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of metanephros development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of metanephros development" (in gray)

Name	Description	Probability	Func Analog Organism
LOC100365106	rCG32755-like	0.742
Rnf213	ring finger protein 213	0.313
Parp14	poly (ADP-ribose) polymerase family, member 14	0.305
Stat1	signal transducer and activator of transcription 1	0.245
LOC100362108	poly (ADP-ribose) polymerase family, member 10	0.211
Eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2	0.161
Stat2	signal transducer and activator of transcription 2	0.123	Rat
Socs3	suppressor of cytokine signaling 3	0.112
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.107
Ifi35	interferon-induced protein 35	0.102
Sp110	SP110 nuclear body protein	0.096
Nek9	NIMA (never in mitosis gene a)- related kinase 9	0.093
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.089
Dtx3l	deltex 3-like (Drosophila)	0.084
Irf7	interferon regulatory factor 7	0.074
RT1-S3	RT1 class Ib, locus S3	0.072
Parp9	poly (ADP-ribose) polymerase family, member 9	0.070
Gata3	GATA binding protein 3	0.056
Clic4	chloride intracellular channel 4	0.049
Igtp	interferon gamma induced GTPase	0.048
Bcl2l1	Bcl2-like 1	0.047
Rara	retinoic acid receptor, alpha	0.045
Il6st	interleukin 6 signal transducer	0.041
Tfeb	transcription factor EB	0.039
Pim1	pim-1 oncogene	0.039
Smad1	SMAD family member 1	0.036
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.036
Lgals3bp	lectin, galactoside-binding, soluble, 3 binding protein	0.035
Hoxc4	homeo box C4	0.035
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.034
Myo1c	myosin IC	0.032
Rsad2	radical S-adenosyl methionine domain containing 2	0.032
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.031
Plxnb2	plexin B2	0.031
Limd1	LIM domains containing 1	0.031
Klf6	Kruppel-like factor 6	0.030
Tgfbr3	transforming growth factor, beta receptor III	0.030
Flt1	FMS-related tyrosine kinase 1	0.027
Skap1	src kinase associated phosphoprotein 1	0.027
Irf1	interferon regulatory factor 1	0.027
Irgm	immunity-related GTPase family, M	0.027
Pcsk7	proprotein convertase subtilisin/kexin type 7	0.026
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.026
Usp18	ubiquitin specific peptidase 18	0.025
Mef2d	myocyte enhancer factor 2D	0.025
RGD1305793	similar to hypothetical protein FLJ20154	0.025
A2m	alpha-2-macroglobulin	0.025
Stk38	serine/threonine kinase 38	0.024
Ifi27	interferon, alpha-inducible protein 27	0.024
Mylk2	myosin light chain kinase 2	0.023
Map3k3	mitogen activated protein kinase kinase kinase 3	0.023
Tgfbr2	transforming growth factor, beta receptor II	0.023
Hdac7	histone deacetylase 7	0.023
Ube2l6	ubiquitin-conjugating enzyme E2L 6	0.023
Irs1	insulin receptor substrate 1	0.023
Cish	cytokine inducible SH2-containing protein	0.022
Klf13	Kruppel-like factor 13	0.022
Nos3	nitric oxide synthase 3, endothelial cell	0.022
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.022
Bmp7	bone morphogenetic protein 7	0.022
Igf1r	insulin-like growth factor 1 receptor	0.022
Sbk1	SH3-binding domain kinase 1	0.021
Ddx58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.020
Flnb	filamin, beta	0.020
Fgg	fibrinogen gamma chain	0.020
Pdzk1ip1	PDZK1 interacting protein 1	0.020
Irs3	insulin receptor substrate 3	0.020
Gna12	guanine nucleotide binding protein (G protein) alpha 12	0.020
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.019
Acap1	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1	0.019
Actc1	actin, alpha, cardiac muscle 1	0.019
Rxra	retinoid X receptor alpha	0.018
Il1r1	interleukin 1 receptor, type I	0.018
Cd47	Cd47 molecule	0.018
Tcf3	transcription factor 3	0.018
Ppp1r15a	protein phosphatase 1, regulatory (inhibitor) subunit 15A	0.018
Kdm6b	lysine (K)-specific demethylase 6B	0.017
Ece1	endothelin converting enzyme 1	0.017
Epor	erythropoietin receptor	0.017
Fga	fibrinogen alpha chain	0.017
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.017
Ptpn1	protein tyrosine phosphatase, non-receptor type 1	0.017
Bcl2	B-cell CLL/lymphoma 2	0.016
Mx2	myxovirus (influenza virus) resistance 2	0.016
Akap13	A kinase (PRKA) anchor protein 13	0.016
Art2	ADP-ribosyltransferase 2	0.016
Hoxb7	homeo box B7	0.016
Cxcl10	chemokine (C-X-C motif) ligand 10	0.016
Irf9	interferon regulatory factor 9	0.015
Lhx1	LIM homeobox 1	0.015
Gja5	gap junction protein, alpha 5	0.015
Cytl1	cytokine like 1	0.015
Rps6ka1	ribosomal protein S6 kinase polypeptide 1	0.015
Ppp1r12a	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.015
Jun	Jun oncogene	0.015
Myh9	myosin, heavy chain 9, non-muscle	0.015
Zfp36	zinc finger protein 36	0.014
Lfng	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	0.014
Fat2	FAT tumor suppressor homolog 2 (Drosophila)	0.014
Pou2f2	POU class 2 homeobox 2	0.014
Tpsb2	tryptase beta 2	0.014
Il4ra	interleukin 4 receptor, alpha	0.014
LOC690000	similar to CG3740-PA	0.014
Arnt	aryl hydrocarbon receptor nuclear translocator	0.014
Clcnkb	chloride channel Kb	0.014
Slc39a14	solute carrier family 39 (zinc transporter), member 14	0.013
Tpsab1	tryptase alpha/beta 1	0.013
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.013
Testin	testin gene	0.013
Fgr	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.013
Amelx	amelogenin X chromosome	0.013
Hyal2	hyaluronoglucosaminidase 2	0.013
Gabrr2	gamma-aminobutyric acid (GABA) receptor, rho 2	0.013
Timp3	TIMP metallopeptidase inhibitor 3	0.013
Ddr1	discoidin domain receptor tyrosine kinase 1	0.013
Fut4	fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)	0.013
Scnn1b	sodium channel, nonvoltage-gated 1, beta	0.013
LOC619574	hypothetical protein LOC619574	0.013
Myog	myogenin	0.013
Egfl7	EGF-like-domain, multiple 7	0.012
Sh2d4a	SH2 domain containing 4A	0.012
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.012
Syde1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)	0.012
Myo1e	myosin IE	0.012
Dnah7	dynein, axonemal, heavy polypeptide 7	0.012
Cp	ceruloplasmin	0.012
Cad	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	0.012
Rarg	retinoic acid receptor, gamma	0.012
Kcnq1	potassium voltage-gated channel, KQT-like subfamily, member 1	0.012
Tln1	talin 1	0.012
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.012
Grin3a	glutamate receptor, ionotropic, N-methyl-D-aspartate 3A	0.012
Itgb4	integrin, beta 4	0.012
Adora2a	adenosine A2a receptor	0.012
Nab1	Ngfi-A binding protein 1	0.012
Eif2c2	eukaryotic translation initiation factor 2C, 2	0.011
Lgals9	lectin, galactoside-binding, soluble, 9	0.011
Lama5	laminin, alpha 5	0.011
Akap1	A kinase (PRKA) anchor protein 1	0.011
Ung	uracil-DNA glycosylase	0.011
Prkch	protein kinase C, eta	0.011
Stap2	signal transducing adaptor family member 2	0.011
Psen1	presenilin 1	0.011
Amh	anti-Mullerian hormone	0.011
Ltbp3	latent transforming growth factor beta binding protein 3	0.011
RGD735175	hypothetical protein MGC:72616	0.011
Ttn	titin	0.011
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.011
Mov10	Moloney leukemia virus 10	0.011
Steap2	six transmembrane epithelial antigen of the prostate 2	0.011
Tor1aip1	torsin A interacting protein 1	0.011
Gsk3b	glycogen synthase kinase 3 beta	0.011
Gns	glucosamine (N-acetyl)-6-sulfatase	0.011
Ager	advanced glycosylation end product-specific receptor	0.011
Irf2	interferon regulatory factor 2	0.011
Dcc	deleted in colorectal carcinoma	0.011
Bcl3	B-cell CLL/lymphoma 3	0.011
Creb3l1	cAMP responsive element binding protein 3-like 1	0.011
Eif4g1	eukaryotic translation initiation factor 4 gamma, 1	0.011
Agtr2	angiotensin II receptor, type 2	0.010
Nfic	nuclear factor I/C	0.010
Ccdc8	coiled-coil domain containing 8	0.010
Cryge	crystallin, gamma E	0.010
Sardh	sarcosine dehydrogenase	0.010
Cast	calpastatin	0.010
Aanat	arylalkylamine N-acetyltransferase	0.010
Ednra	endothelin receptor type A	0.010
Prl3d1	Prolactin family 3, subfamily d, member 1	0.010
Casp7	caspase 7	0.010
Cpne3	copine III	0.010
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.010
Ceacam11	carcinoembryonic antigen-related cell adhesion molecule 11	0.010